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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35404844
log Bayes Factor = 99.3549
Chromosome 6   position 33,269,881  (GRCh37) Explore rs35404844 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
K90 Intestinal malabsorption
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
K90-K93 Other diseases of the digestive system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
H30-H36 Disorders of choroid and retina
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
H36 Retinal disorders in diseases classified elsewhere
0.996 0.004 0.000
H36.0 Diabetic retinopathy
0.995 0.005 0.000
K70-K77 Diseases of liver
0.994 0.006 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.993 0.007 0.000
E10.3 With ophthalmic complications
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
I63 Cerebral infarction
0.991 0.009 0.000
M20-M25 Other joint disorders
0.991 0.009 0.000
Chapter VIII Diseases of the ear and mastoid process
0.988 0.012 0.000
K29.8 Duodenitis
0.985 0.015 0.000
K25 Gastric ulcer
0.983 0.017 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.982 0.018 0.000
Chapter XX External causes of morbidity and mortality
0.982 0.018 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.982 0.018 0.000
K75 Other inflammatory liver diseases
0.980 0.020 0.000
K29 Gastritis and duodenitis
0.980 0.020 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.979 0.021 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.974 0.026 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.971 0.029 0.000
O36 Maternal care for other known or suspected foetal problems
0.967 0.033 0.000
M35 Other systemic involvement of connective tissue
0.965 0.035 0.000
I65.2 Occlusion and stenosis of carotid artery
0.964 0.036 0.000
M21 Other acquired deformities of limbs
0.952 0.048 0.000
M35.0 Sicca syndrome [Sjogren]
0.951 0.049 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.946 0.054 0.000
O36.8 Maternal care for other specified foetal problems
0.946 0.054 0.000
E10.1 With ketoacidosis
0.942 0.058 0.000
H60-H62 Diseases of external ear
0.939 0.061 0.000
I30-I52 Other forms of heart disease
0.937 0.063 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.933 0.067 0.000
I34 Nonrheumatic mitral valve disorders
0.925 0.075 0.000
K75.4 Autoimmune hepatitis
0.923 0.077 0.000
H35 Other retinal disorders
0.914 0.086 0.000
I34.0 Mitral (valve) insufficiency
0.914 0.086 0.000
I45 Other conduction disorders
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.912 0.088 0.000
H61 Other disorders of external ear
0.911 0.089 0.000
I63.8 Other cerebral infarction
0.907 0.093 0.000
Y86 Sequelae of other accidents
0.905 0.095 0.000
K22 Other diseases of oesophagus
0.904 0.096 0.000
E20-E35 Disorders of other endocrine glands
0.903 0.097 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.900 0.100 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.897 0.103 0.000
K73 Chronic hepatitis, not elsewhere classified
0.894 0.106 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.892 0.108 0.000
H65-H75 Diseases of middle ear and mastoid
0.891 0.109 0.000
K75.8 Other specified inflammatory liver diseases
0.889 0.111 0.000
H33 Retinal detachments and breaks
0.886 0.114 0.000
M34 Systemic sclerosis
0.881 0.119 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.881 0.119 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.876 0.124 0.000
W00-W19 Falls
0.876 0.124 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.868 0.132 0.000
M23 Internal derangement of knee
0.865 0.135 0.000
I47 Paroxysmal tachycardia
0.864 0.136 0.000
I60 Subarachnoid haemorrhage
0.863 0.137 0.000
O36.9 Maternal care for foetal problem, unspecified
0.862 0.138 0.000
K90.9 Intestinal malabsorption, unspecified
0.858 0.142 0.000
M21.0 Valgus deformity, not elsewhere classified
0.855 0.145 0.000
M24 Other specific joint derangements
0.853 0.147 0.000
H61.0 Perichondritis of external ear
0.851 0.149 0.000
K22.7 Barrett's oesophagus
0.847 0.153 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.846 0.154 0.000
H80-H83 Diseases of inner ear
0.846 0.154 0.000
K74 Fibrosis and cirrhosis of liver
0.836 0.164 0.000
E11 Non-insulin-dependent diabetes mellitus
0.835 0.165 0.000
E27 Other disorders of adrenal gland
0.834 0.166 0.000
O44 Placenta praevia
0.832 0.168 0.000
O47 False labour
0.828 0.172 0.000
K22.8 Other specified diseases of oesophagus
0.827 0.173 0.000
E11.3 With ophthalmic complications
0.824 0.176 0.000
K22.9 Disease of oesophagus, unspecified
0.822 0.178 0.000
I49 Other cardiac arrhythmias
0.822 0.178 0.000
H35.8 Other specified retinal disorders
0.818 0.182 0.000
E10.2 With renal complications
0.816 0.184 0.000
M65-M68 Disorders of synovium and tendon
0.815 0.185 0.000
E14 Unspecified diabetes mellitus
0.815 0.185 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.814 0.186 0.000
K25.3 Acute without haemorrhage or perforation
0.813 0.187 0.000
E10.4 With neurological complications
0.812 0.187 0.000
I45.9 Conduction disorder, unspecified
0.811 0.189 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.806 0.194 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.806 0.194 0.000
O36.4 Maternal care for intra-uterine death
0.805 0.195 0.000
E27.1 Primary adrenocortical insufficiency
0.803 0.197 0.000
I45.1 Other and unspecified right bundle-branch block
0.798 0.202 0.000
V40-V49 Car occupant injured in transport accident
0.797 0.203 0.000
H61.2 Impacted cerumen
0.795 0.205 0.000
H33.2 Serous retinal detachment
0.795 0.205 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.795 0.205 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.795 0.205 0.000
I62 Other nontraumatic intracranial haemorrhage
0.793 0.207 0.000
K75.9 Inflammatory liver disease, unspecified
0.793 0.207 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.793 0.207 0.000
D60-D64 Aplastic and other anaemias
0.792 0.208 0.000
M80-M85 Disorders of bone density and structure
0.791 0.208 0.000
I73 Other peripheral vascular diseases
0.790 0.210 0.000
M33 Dermatopolymyositis
0.790 0.210 0.000
O41 Other disorders of amniotic fluid and membranes
0.789 0.210 0.000
I47.2 Ventricular tachycardia
0.786 0.214 0.000
H72 Perforation of tympanic membrane
0.785 0.215 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.780 0.220 0.000
K73.9 Chronic hepatitis, unspecified
0.779 0.221 0.000
M32 Systemic lupus erythematosus
0.779 0.221 0.000
O16 Unspecified maternal hypertension
0.777 0.223 0.000
E40-E46 Malnutrition
0.776 0.223 0.000
M70-M79 Other soft tissue disorders
0.776 0.224 0.000
E16 Other disorders of pancreatic internal secretion
0.773 0.227 0.000
M21.1 Varus deformity, not elsewhere classified
0.772 0.228 0.000
I74 Arterial embolism and thrombosis
0.772 0.228 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.771 0.229 0.000
H69 Other disorders of Eustachian tube
0.769 0.231 0.000
Q50-Q56 Congenital malformations of genital organs
0.769 0.231 0.000
M21.4 Flat foot [pes planus] (acquired)
0.765 0.235 0.000
M60-M63 Disorders of muscles
0.765 0.235 0.000
O36.6 Maternal care for excessive foetal growth
0.764 0.236 0.000
O85-O92 Complications predominantly related to the puerperium
0.763 0.237 0.000
Chapter I Certain infectious and parasitic diseases
0.762 0.238 0.000
H25-H28 Disorders of lens
0.762 0.238 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.762 0.238 0.000
M00-M03 Infectious arthropathies
0.761 0.239 0.000
I45.2 Bifascicular block
0.761 0.239 0.000
Chapter V Mental and behavioural disorders
0.760 0.240 0.000
I69 Sequelae of cerebrovascular disease
0.759 0.241 0.000
E10.5 With peripheral circulatory complications
0.757 0.243 0.000
H74 Other disorders of middle ear and mastoid
0.755 0.245 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.754 0.246 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.753 0.247 0.000
M34.9 Systemic sclerosis, unspecified
0.753 0.247 0.000
V20-V29 Motorcycle rider injured in transport accident
0.750 0.249 0.000
K75.0 Abscess of liver
0.750 0.250 0.000
W19 Unspecified fall
0.750 0.250 0.000
I45.6 Preexcitation syndrome
0.750 0.250 0.000
W50-W64 Exposure to animate mechanical forces
0.748 0.252 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.747 0.253 0.000
M21.2 Flexion deformity
0.747 0.253 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.744 0.256 0.000
E22 Hyperfunction of pituitary gland
0.743 0.257 0.000
H35.4 Peripheral retinal degeneration
0.743 0.257 0.000
F05.9 Delirium, unspecified
0.743 0.257 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.743 0.257 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.741 0.259 0.000
H55-H59 Other disorders of eye and adnexa
0.739 0.261 0.000
M23.8 Other internal derangements of knee
0.738 0.262 0.000
K70 Alcoholic liver disease
0.737 0.263 0.000
H33.1 Retinoschisis and retinal cysts
0.737 0.263 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.736 0.264 0.000
H35.0 Background retinopathy and retinal vascular changes
0.736 0.264 0.000
O43 Placental disorders
0.735 0.264 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.735 0.265 0.000
M24.1 Other articular cartilage disorders
0.734 0.265 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.734 0.266 0.000
M35.7 Hypermobility syndrome
0.734 0.266 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.734 0.266 0.000
M91-M94 Chondropathies
0.734 0.266 0.000
X20-X29 Contact with venomous animals and plants
0.733 0.267 0.000
O36.5 Maternal care for poor foetal growth
0.732 0.268 0.000
M23.4 Loose body in knee
0.731 0.268 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.730 0.270 0.000
D50-D53 Nutritional anaemias
0.730 0.270 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.730 0.270 0.000
E13 Other specified diabetes mellitus
0.730 0.270 0.000
K25.4 Chronic or unspecified with haemorrhage
0.727 0.273 0.000
X10-X19 Contact with heat and hot substances
0.727 0.273 0.000
M34.8 Other forms of systemic sclerosis
0.727 0.273 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.726 0.274 0.000
H80 Otosclerosis
0.725 0.275 0.000
K22.3 Perforation of oesophagus
0.725 0.275 0.000
M67 Other disorders of synovium and tendon
0.723 0.277 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.723 0.277 0.000
W18 Other fall on same level
0.721 0.279 0.000
H73 Other disorders of tympanic membrane
0.720 0.280 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.720 0.280 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E10.0 With coma
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E05.8 Other thyrotoxicosis
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
K90.8 Other intestinal malabsorption
0.717 0.283 0.000
K90.3 Pancreatic steatorrhoea
0.717 0.283 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.717 0.283 0.000
K90.1 Tropical sprue
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.715 0.285 0.000
H31 Other disorders of choroid
0.715 0.285 0.000
H30 Chorioretinal inflammation
0.715 0.285 0.000
M86-M90 Other osteopathies
0.715 0.285 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.714 0.286 0.000
K77 Liver disorders in diseases classified elsewhere
0.713 0.287 0.000
K71 Toxic liver disease
0.713 0.287 0.000
K28 Gastrojejunal ulcer
0.712 0.288 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.712 0.288 0.000
O44.1 Placenta praevia with haemorrhage
0.712 0.288 0.000
I34.1 Mitral (valve) prolapse
0.712 0.288 0.000
X60-X84 Intentional self-harm
0.711 0.288 0.000
D64 Other anaemias
0.711 0.288 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.711 0.289 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.711 0.289 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.711 0.289 0.000
E34 Other endocrine disorders
0.711 0.289 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.710 0.289 0.000
M30 Polyarteritis nodosa and related conditions
0.710 0.289 0.000
H72.8 Other perforations of tympanic membrane
0.710 0.290 0.000
I47.1 Supraventricular tachycardia
0.709 0.291 0.000
M23.5 Chronic instability of knee
0.707 0.293 0.000
K29.0 Acute haemorrhagic gastritis
0.706 0.294 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.706 0.294 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.705 0.295 0.000
K22.0 Achalasia of cardia
0.705 0.295 0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.705 0.295 0.000
K25.5 Chronic or unspecified with perforation
0.705 0.295 0.000
K25.2 Acute with both haemorrhage and perforation
0.705 0.295 0.000
K25.1 Acute with perforation
0.705 0.295 0.000
K25.0 Acute with haemorrhage
0.705 0.295 0.000
E16.2 Hypoglycaemia, unspecified
0.705 0.295 0.000
D80-D89 Certain disorders involving the immune mechanism
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.704 0.296 0.000
Y10-Y34 Event of undetermined intent
0.704 0.296 0.000
Y00-Y09 Assault
0.704 0.296 0.000
X85-X99 Assault
0.704 0.296 0.000
X50-X57 Overexertion, travel and privation
0.704 0.296 0.000
X30-X39 Exposure to forces of nature
0.704 0.296 0.000
X00-X09 Exposure to smoke, fire and flames
0.704 0.296 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.704 0.296 0.000
W75-W84 Other accidental threats to breathing
0.704 0.296 0.000
W65-W74 Accidental drowning and submersion
0.704 0.296 0.000
V98-V99 Other and unspecified transport accidents
0.704 0.296 0.000
V95-V97 Air and space transport accidents
0.704 0.296 0.000
V90-V94 Water transport accidents
0.704 0.296 0.000
V70-V79 Bus occupant injured in transport accident
0.704 0.296 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.704 0.296 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.704 0.296 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.704 0.296 0.000
V01-V09 Pedestrian injured in transport accident
0.704 0.296 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.704 0.296 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.704 0.296 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.704 0.296 0.000
I65.1 Occlusion and stenosis of basilar artery
0.704 0.296 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.702 0.298 0.000
K75.2 Nonspecific reactive hepatitis
0.702 0.298 0.000
K75.1 Phlebitis of portal vein
0.702 0.298 0.000
K29.9 Gastroduodenitis, unspecified
0.702 0.298 0.000
K11 Diseases of salivary glands
0.701 0.299 0.000
I37 Pulmonary valve disorders
0.700 0.300 0.000
H90-H95 Other disorders of ear
0.699 0.301 0.000
K74.6 Other and unspecified cirrhosis of liver
0.699 0.301 0.000
I49.5 Sick sinus syndrome
0.699 0.301 0.000
O45 Premature separation of placenta [abruptio placentae]
0.699 0.301 0.000
O33 Maternal care for known or suspected disproportion
0.699 0.301 0.000
O31 Complications specific to multiple gestation
0.699 0.301 0.000
O40 Polyhydramnios
0.699 0.301 0.000
H61.3 Acquired stenosis of external ear canal
0.698 0.302 0.000
D61 Other aplastic anaemias
0.698 0.302 0.000
M77 Other enthesopathies
0.698 0.302 0.000
I73.0 Raynaud's syndrome
0.698 0.302 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.697 0.303 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.695 0.305 0.000
H26 Other cataract
0.695 0.305 0.000
H35.7 Separation of retinal layers
0.693 0.307 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.693 0.307 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.693 0.307 0.000
O36.2 Maternal care for hydrops foetalis
0.693 0.307 0.000
O36.1 Maternal care for other isoimmunisation
0.693 0.307 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.693 0.307 0.000
Y88 Sequelae of surgical and medical care as external cause
0.693 0.307 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.693 0.307 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.692 0.308 0.000
M35.8 Other specified systemic involvement of connective tissue
0.692 0.308 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.692 0.308 0.000
M35.5 Multifocal fibrosclerosis
0.692 0.308 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.692 0.308 0.000
M35.2 Behcet's disease
0.692 0.308 0.000
M35.1 Other overlap syndromes
0.692 0.308 0.000
W19.9 Unspecified place
0.691 0.309 0.000
E06 Thyroiditis
0.688 0.312 0.000
H34 Retinal vascular occlusions
0.688 0.312 0.000
I49.8 Other specified cardiac arrhythmias
0.687 0.313 0.000
M21.6 Other acquired deformities of ankle and foot
0.687 0.313 0.000
W05 Fall involving wheelchair
0.686 0.314 0.000
H61.8 Other specified disorders of external ear
0.684 0.315 0.000
Q00-Q07 Congenital malformations of the nervous system
0.684 0.316 0.000
K72 Hepatic failure, not elsewhere classified
0.683 0.317 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.683 0.317 0.000
M21.9 Acquired deformity of limb, unspecified
0.683 0.317 0.000
M21.8 Other specified acquired deformities of limbs
0.683 0.317 0.000
M21.7 Unequal limb length (acquired)
0.683 0.317 0.000
H35.6 Retinal haemorrhage
0.680 0.320 0.000
Q60-Q64 Congenital malformations of the urinary system
0.680 0.320 0.000
Q80-Q89 Other congenital malformations
0.678 0.321 0.000
H43-H45 Disorders of vitreous body and globe
0.677 0.323 0.000
W15 Fall from cliff
0.676 0.324 0.000
M23.0 Cystic meniscus
0.675 0.325 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.675 0.325 0.000
W20-W49 Exposure to inanimate mechanical forces
0.674 0.326 0.000
H33.0 Retinal detachment with retinal break
0.673 0.327 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.673 0.327 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.672 0.327 0.000
M21.3 Wrist or foot drop (acquired)
0.672 0.328 0.000
I52 Other heart disorders in diseases classified elsewhere
0.672 0.328 0.000
I48 Atrial fibrillation and flutter
0.672 0.328 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.672 0.328 0.000
I41 Myocarditis in diseases classified elsewhere
0.672 0.328 0.000
I40 Acute myocarditis
0.672 0.328 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.672 0.328 0.000
I32 Pericarditis in diseases classified elsewhere
0.672 0.328 0.000
H50 Other strabismus
0.670 0.330 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.670 0.330 0.000
Y89 Sequelae of other external causes
0.669 0.331 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.669 0.331 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.669 0.331 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.669 0.331 0.000
E14.9 Without complications
0.667 0.333 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.667 0.333 0.000
M77.1 Lateral epicondylitis
0.667 0.333 0.000
K25.7 Chronic without haemorrhage or perforation
0.667 0.333 0.000
M70.6 Trochanteric bursitis
0.667 0.333 0.000
M23.9 Internal derangement of knee, unspecified
0.666 0.333 0.000
D55-D59 Haemolytic anaemias
0.666 0.334 0.000
E04 Other non-toxic goitre
0.666 0.334 0.000
V80-V89 Other land transport accidents
0.665 0.334 0.000
I45.8 Other specified conduction disorders
0.665 0.335 0.000
H70 Mastoiditis and related conditions
0.665 0.335 0.000
B15-B19 Viral hepatitis
0.665 0.335 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.663 0.337 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.663 0.337 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.663 0.337 0.000
K27 Peptic ulcer, site unspecified
0.663 0.337 0.000
M80 Osteoporosis with pathological fracture
0.663 0.337 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.661 0.338 0.000
I49.0 Ventricular fibrillation and flutter
0.660 0.340 0.000
H81 Disorders of vestibular function
0.660 0.340 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.659 0.341 0.000
I36 Nonrheumatic tricuspid valve disorders
0.656 0.344 0.000
K30 Dyspepsia
0.656 0.344 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.656 0.344 0.000
H35.5 Hereditary retinal dystrophy
0.655 0.344 0.000
H35.2 Other proliferative retinopathy
0.655 0.344 0.000
H35.1 Retinopathy of prematurity
0.655 0.344 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.655 0.345 0.000
I45.4 Nonspecific intraventricular block
0.654 0.346 0.000
I45.0 Right fascicular block
0.654 0.346 0.000
D64.9 Anaemia, unspecified
0.654 0.346 0.000
W08 Fall involving other furniture
0.654 0.346 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.654 0.346 0.000
Q35-Q37 Cleft lip and cleft palate
0.654 0.346 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.654 0.346 0.000
H61.9 Disorder of external ear, unspecified
0.653 0.347 0.000
E28 Ovarian dysfunction
0.653 0.347 0.000
O46.9 Antepartum haemorrhage, unspecified
0.652 0.348 0.000
M82 Osteoporosis in diseases classified elsewhere
0.651 0.349 0.000
O46.8 Other antepartum haemorrhage
0.651 0.349 0.000
M31 Other necrotising vasculopathies
0.650 0.349 0.000
K29.4 Chronic atrophic gastritis
0.650 0.350 0.000
M66 Spontaneous rupture of synovium and tendon
0.650 0.350 0.000
I47.0 Reentry ventricular arrhythmia
0.649 0.351 0.000
K74.5 Biliary cirrhosis, unspecified
0.649 0.351 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.648 0.352 0.000
E32 Diseases of thymus
0.648 0.352 0.000
E31 Polyglandular dysfunction
0.648 0.352 0.000
E30 Disorders of puberty, not elsewhere classified
0.648 0.352 0.000
E26 Hyperaldosteronism
0.648 0.352 0.000
E25 Adrenogenital disorders
0.648 0.352 0.000
E24 Cushing's syndrome
0.648 0.352 0.000
E20 Hypoparathyroidism
0.648 0.352 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.647 0.352 0.000
O48 Prolonged pregnancy
0.648 0.352 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.647 0.353 0.000
E29 Testicular dysfunction
0.647 0.353 0.000
H72.0 Central perforation of tympanic membrane
0.646 0.354 0.000
M33.1 Other dermatomyositis
0.646 0.354 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.646 0.354 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.645 0.355 0.000
K29.3 Chronic superficial gastritis
0.645 0.355 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.645 0.355 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.643 0.357 0.000
O15 Eclampsia
0.643 0.357 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.643 0.357 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.643 0.357 0.000
I45.5 Other specified heart block
0.643 0.357 0.000
W10 Fall on and from stairs and steps
0.643 0.357 0.000
K05 Gingivitis and periodontal diseases
0.643 0.357 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.641 0.359 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.641 0.359 0.000
I45.3 Trifascicular block
0.641 0.359 0.000
I73.9 Peripheral vascular disease, unspecified
0.641 0.359 0.000
K73.8 Other chronic hepatitis, not elsewhere classified
0.641 0.359 0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.641 0.359 0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.641 0.359 0.000
K29.1 Other acute gastritis
0.640 0.360 0.000
O47.9 False labour, unspecified
0.639 0.360 0.000
H80.9 Otosclerosis, unspecified
0.639 0.361 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.639 0.361 0.000
H26.4 After-cataract
0.639 0.361 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.639 0.361 0.000
H68 Eustachian salpingitis and obstruction
0.639 0.361 0.000
H67 Otitis media in diseases classified elsewhere
0.639 0.361 0.000
M70.65 Trochanteric bursitis-Pelvic/Thigh
0.639 0.361 0.000
H61.1 Non-infective disorders of pinna
0.638 0.362 0.000
M22 Disorders of patella
0.637 0.363 0.000
E07 Other disorders of thyroid
0.637 0.363 0.000
K08 Other disorders of teeth and supporting structures
0.637 0.363 0.000
E65-E68 Obesity and other hyperalimentation
0.636 0.364 0.000
M23.49 Loose body in knee-Unspec lig/men
0.636 0.364 0.000
H69.8 Other specified disorders of Eustachian tube
0.636 0.364 0.000
H33.4 Traction detachment of retina
0.635 0.365 0.000
M15-M19 Arthrosis
0.634 0.366 0.000
K74.0 Hepatic fibrosis
0.633 0.367 0.000
I49.3 Ventricular premature depolarisation
0.633 0.367 0.000
I63.9 Cerebral infarction, unspecified
0.633 0.367 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.633 0.367 0.000
I70 Atherosclerosis
0.632 0.368 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.632 0.368 0.000
W18.5 Trade and service area
0.632 0.368 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.631 0.368 0.000
M34.1 CR(E)ST syndrome
0.631 0.368 0.000
M34.0 Progressive systemic sclerosis
0.631 0.368 0.000
D61.9 Aplastic anaemia, unspecified
0.631 0.369 0.000
V10-V19 Pedal cyclist injured in transport accident
0.631 0.369 0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.631 0.369 0.000
I74.5 Embolism and thrombosis of iliac artery
0.631 0.369 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.630 0.370 0.000
O41.0 Oligohydramnios
0.629 0.371 0.000
W17 Other fall from one level to another
0.628 0.372 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.628 0.372 0.000
W14 Fall from tree
0.628 0.372 0.000
W12 Fall on and from scaffolding
0.628 0.372 0.000
W11 Fall on and from ladder
0.628 0.372 0.000
W09 Fall involving playground equipment
0.628 0.372 0.000
W04 Fall while being carried or supported by other persons
0.628 0.372 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.628 0.372 0.000
W00 Fall on same level involving ice and snow
0.628 0.372 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.627 0.373 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.627 0.373 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.626 0.373 0.000
H69.9 Eustachian tube disorder, unspecified
0.626 0.374 0.000
D50 Iron deficiency anaemia
0.625 0.375 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.624 0.376 0.000
K11.1 Hypertrophy of salivary gland
0.624 0.376 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.623 0.376 0.000
I30 Acute pericarditis
0.623 0.377 0.000
E15 Nondiabetic hypoglycaemic coma
0.622 0.378 0.000
M18 Arthrosis of first carpometacarpal joint
0.622 0.378 0.000
M23.1 Discoid meniscus (congenital)
0.620 0.380 0.000
Y95 Nosocomial condition
0.620 0.380 0.000
O86 Other puerperal infections
0.619 0.381 0.000
I31 Other diseases of pericardium
0.619 0.381 0.000
I60.8 Other subarachnoid haemorrhage
0.619 0.381 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.619 0.381 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.619 0.381 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.619 0.381 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.619 0.381 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.619 0.381 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.619 0.381 0.000
V48 Car occupant injured in noncollision transport accident
0.617 0.382 0.000
M24.5 Contracture of joint
0.617 0.383 0.000
E46 Unspecified protein-energy malnutrition
0.616 0.384 0.000
H90 Conductive and sensorineural hearing loss
0.615 0.384 0.000
E11.8 With unspecified complications
0.615 0.385 0.000
O42 Premature rupture of membranes
0.614 0.386 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.613 0.387 0.000
M21.08 Valgus deformity, not elsewhere classified (Other)
0.613 0.387 0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.613 0.387 0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.613 0.387 0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.613 0.387 0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.613 0.387 0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.613 0.387 0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.613 0.387 0.000
H35.9 Retinal disorder, unspecified
0.612 0.388 0.000
M24.9 Joint derangement, unspecified
0.611 0.389 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.611 0.389 0.000
M24.7 Protrusio acetabuli
0.611 0.389 0.000
M24.6 Ankylosis of joint
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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