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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs35487354
log Bayes Factor = 14.9055
Chromosome 11   position 65,366,882  (GRCh37) Explore rs35487354 on Ensembl!
Variant rs35487354 is part of Cluster X0320

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
B95-B98 Bacterial, viral and other infectious agents
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.998 0.002 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.997 0.003 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.995 0.005 0.000
E03 Other hypothyroidism
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.992 0.008 0.000
E03.9 Hypothyroidism, unspecified
0.992 0.008 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.989 0.011 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.988 0.012 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.986 0.014 0.000
N40-N51 Diseases of male genital organs
0.985 0.015 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.973 0.027 0.000
N17-N19 Renal failure
0.970 0.030 0.000
Chapter II Neoplasms
0.969 0.031 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.957 0.043 0.000
M15-M19 Arthrosis
0.954 0.046 0.000
E86 Volume depletion
0.949 0.051 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.945 0.055 0.000
Chapter IX Diseases of the circulatory system
0.943 0.057 0.000
N18 Chronic renal failure
0.943 0.057 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.937 0.063 0.000
E10-E14 Diabetes mellitus
0.934 0.066 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.933 0.067 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.931 0.069 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.928 0.072 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.927 0.073 0.000
M16 Coxarthrosis [arthrosis of hip]
0.926 0.074 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.926 0.074 0.000
Chapter VI Diseases of the nervous system
0.925 0.075 0.000
C64-C68 Malignant neoplasms of urinary tract
0.920 0.080 0.000
E83 Disorders of mineral metabolism
0.919 0.081 0.000
Chapter XX External causes of morbidity and mortality
0.918 0.082 0.000
M16.9 Coxarthrosis, unspecified
0.905 0.095 0.000
M86-M90 Other osteopathies
0.902 0.098 0.000
N18.9 Chronic renal failure, unspecified
0.901 0.099 0.000
M80-M85 Disorders of bone density and structure
0.898 0.102 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.897 0.103 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.891 0.109 0.000
N72 Inflammatory disease of cervix uteri
0.890 0.110 0.000
O00-O08 Pregnancy with abortive outcome
0.890 0.110 0.000
N76 Other inflammation of vagina and vulva
0.890 0.110 0.000
S60-S69 Injuries to the wrist and hand
0.884 0.116 0.000
M20-M25 Other joint disorders
0.883 0.117 0.000
N42 Other disorders of prostate
0.882 0.118 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.879 0.121 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.878 0.122 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.878 0.122 0.000
N48 Other disorders of penis
0.871 0.129 0.000
I30-I52 Other forms of heart disease
0.868 0.132 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.868 0.132 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.868 0.132 0.000
S20-S29 Injuries to the thorax
0.865 0.135 0.000
D60-D64 Aplastic and other anaemias
0.865 0.135 0.000
E11 Non-insulin-dependent diabetes mellitus
0.865 0.135 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.863 0.137 0.000
E83.5 Disorders of calcium metabolism
0.851 0.149 0.000
I49 Other cardiac arrhythmias
0.847 0.153 0.000
M84 Disorders of continuity of bone
0.846 0.154 0.000
S40-S49 Injuries to the shoulder and upper arm
0.845 0.155 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.840 0.160 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.839 0.161 0.000
G40-G47 Episodic and paroxysmal disorders
0.837 0.163 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.835 0.165 0.000
N75 Diseases of Bartholin's gland
0.831 0.169 0.000
M18 Arthrosis of first carpometacarpal joint
0.829 0.171 0.000
N48.6 Balanitis xerotica obliterans
0.829 0.171 0.000
E87.6 Hypokalaemia
0.828 0.172 0.000
A00-A09 Intestinal infectious diseases
0.828 0.172 0.000
M91-M94 Chondropathies
0.828 0.172 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.821 0.179 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.821 0.179 0.000
D64 Other anaemias
0.820 0.180 0.000
I71 Aortic aneurysm and dissection
0.820 0.180 0.000
M20 Acquired deformities of fingers and toes
0.817 0.183 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.817 0.183 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.816 0.184 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.816 0.184 0.000
E85 Amyloidosis
0.813 0.186 0.000
N00-N08 Glomerular diseases
0.812 0.188 0.000
O80-O84 Delivery
0.810 0.190 0.000
E10 Insulin-dependent diabetes mellitus
0.810 0.190 0.000
O04 Medical abortion
0.810 0.190 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.807 0.193 0.000
E20-E35 Disorders of other endocrine glands
0.807 0.193 0.000
E11.4 With neurological complications
0.806 0.194 0.000
M65-M68 Disorders of synovium and tendon
0.806 0.194 0.000
N42.8 Other specified disorders of prostate
0.805 0.195 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.805 0.195 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.804 0.196 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.803 0.197 0.000
N73 Other female pelvic inflammatory diseases
0.803 0.197 0.000
E87.5 Hyperkalaemia
0.802 0.198 0.000
C67 Malignant neoplasm of bladder
0.802 0.198 0.000
I49.3 Ventricular premature depolarisation
0.801 0.199 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.801 0.199 0.000
N76.0 Acute vaginitis
0.800 0.200 0.000
N18.0 End-stage renal disease
0.798 0.202 0.000
N19 Unspecified renal failure
0.796 0.204 0.000
N50 Other disorders of male genital organs
0.796 0.204 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.796 0.204 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.794 0.206 0.000
S90-S99 Injuries to the ankle and foot
0.793 0.207 0.000
M86 Osteomyelitis
0.793 0.207 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.792 0.208 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.791 0.209 0.000
E89.0 Postprocedural hypothyroidism
0.791 0.209 0.000
D64.9 Anaemia, unspecified
0.788 0.212 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.788 0.212 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.787 0.213 0.000
D10-D36 Benign neoplasms
0.784 0.216 0.000
T66-T78 Other and unspecified effects of external causes
0.781 0.218 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.780 0.220 0.000
E40-E46 Malnutrition
0.780 0.220 0.000
C92 Myeloid leukaemia
0.779 0.221 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.778 0.222 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.776 0.224 0.000
E73 Lactose intolerance
0.776 0.224 0.000
E88 Other metabolic disorders
0.774 0.226 0.000
B65-B83 Helminthiases
0.773 0.227 0.000
E87.7 Fluid overload
0.773 0.227 0.000
N18.5 Chronic kidney disease, stage 5
0.770 0.230 0.000
E11.5 With peripheral circulatory complications
0.768 0.232 0.000
N99-N99 Other disorders of the genitourinary system
0.767 0.233 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.767 0.233 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.766 0.234 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.764 0.236 0.000
I72 Other aneurysm
0.764 0.236 0.000
I73 Other peripheral vascular diseases
0.764 0.236 0.000
W20-W49 Exposure to inanimate mechanical forces
0.763 0.237 0.000
D41.4 Bladder
0.763 0.237 0.000
S62 Fracture at wrist and hand level
0.760 0.240 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.759 0.241 0.000
C91 Lymphoid leukaemia
0.758 0.242 0.000
D80-D89 Certain disorders involving the immune mechanism
0.758 0.242 0.000
M20.5 Other deformities of toe(s) (acquired)
0.758 0.242 0.000
E87.3 Alkalosis
0.757 0.243 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.757 0.243 0.000
S61 Open wound of wrist and hand
0.753 0.247 0.000
O04.9 Complete or unspecified, without complication
0.752 0.248 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.751 0.249 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.749 0.251 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.749 0.251 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.748 0.252 0.000
G70-G73 Diseases of myoneural junction and muscle
0.748 0.252 0.000
G40 Epilepsy
0.746 0.254 0.000
O85-O92 Complications predominantly related to the puerperium
0.745 0.255 0.000
N71 Inflammatory disease of uterus, except cervix
0.744 0.256 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.743 0.257 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.743 0.257 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.742 0.258 0.000
T79-T79 Certain early complications of trauma
0.740 0.259 0.000
M05-M14 Inflammatory polyarthropathies
0.740 0.259 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.740 0.260 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.740 0.260 0.000
I38 Endocarditis, valve unspecified
0.739 0.261 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.737 0.263 0.000
I70 Atherosclerosis
0.736 0.264 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.736 0.264 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.734 0.266 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.733 0.267 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.731 0.269 0.000
G43 Migraine
0.731 0.269 0.000
N18.4 Chronic kidney disease, stage 4
0.730 0.270 0.000
E87.0 Hyperosmolality and hypernatraemia
0.729 0.270 0.000
E10.5 With peripheral circulatory complications
0.729 0.271 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.729 0.271 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.729 0.271 0.000
C66 Malignant neoplasm of ureter
0.727 0.272 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.727 0.273 0.000
M25 Other joint disorders, not elsewhere classified
0.725 0.275 0.000
M19 Other arthrosis
0.723 0.277 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.722 0.278 0.000
X60-X84 Intentional self-harm
0.722 0.278 0.000
N20-N23 Urolithiasis
0.722 0.278 0.000
E11.3 With ophthalmic complications
0.721 0.279 0.000
M31 Other necrotising vasculopathies
0.721 0.279 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.720 0.279 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.720 0.280 0.000
S42 Fracture of shoulder and upper arm
0.719 0.281 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.718 0.282 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A80-A89 Viral infections of the central nervous system
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
E05.9 Thyrotoxicosis, unspecified
0.716 0.284 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.716 0.284 0.000
E06 Thyroiditis
0.715 0.285 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.715 0.285 0.000
E00 Congenital iodine-deficiency syndrome
0.715 0.285 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.715 0.285 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.715 0.285 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.715 0.285 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.715 0.285 0.000
M89 Other disorders of bone
0.714 0.285 0.000
E87.4 Mixed disorder of acid-base balance
0.714 0.286 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.714 0.286 0.000
M86.9 Osteomyelitis, unspecified
0.714 0.286 0.000
T87 Complications peculiar to reattachment and amputation
0.713 0.286 0.000
T86 Failure and rejection of transplanted organs and tissues
0.713 0.286 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.713 0.286 0.000
E83.3 Disorders of phosphorus metabolism
0.713 0.287 0.000
E03.8 Other specified hypothyroidism
0.713 0.287 0.000
E03.5 Myxoedema coma
0.713 0.287 0.000
E03.4 Atrophy of thyroid (acquired)
0.713 0.287 0.000
E03.3 Postinfectious hypothyroidism
0.713 0.287 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.713 0.287 0.000
E03.1 Congenital hypothyroidism without goitre
0.713 0.287 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.713 0.287 0.000
E07 Other disorders of thyroid
0.713 0.287 0.000
A30-A49 Other bacterial diseases
0.713 0.287 0.000
M60-M63 Disorders of muscles
0.712 0.287 0.000
M00-M03 Infectious arthropathies
0.712 0.287 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.711 0.288 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.711 0.288 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.711 0.288 0.000
I49.9 Cardiac arrhythmia, unspecified
0.711 0.289 0.000
I05-I09 Chronic rheumatic heart diseases
0.710 0.290 0.000
I42 Cardiomyopathy
0.710 0.290 0.000
S36 Injury of intra-abdominal organs
0.708 0.292 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.708 0.292 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.707 0.293 0.000
M40-M43 Deforming dorsopathies
0.707 0.293 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.706 0.294 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.706 0.294 0.000
N46 Male infertility
0.706 0.294 0.000
N44 Torsion of testis
0.706 0.294 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.706 0.294 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.705 0.295 0.000
N75.1 Abscess of Bartholin's gland
0.705 0.295 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.704 0.296 0.000
I10-I15 Hypertensive diseases
0.700 0.300 0.000
W00-W19 Falls
0.700 0.300 0.000
I78 Diseases of capillaries
0.699 0.301 0.000
B07 Viral warts
0.699 0.301 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.699 0.301 0.000
N42.2 Atrophy of prostate
0.698 0.302 0.000
N70 Salpingitis and oophoritis
0.697 0.303 0.000
N50.1 Vascular disorders of male genital organs
0.696 0.304 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.695 0.305 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.695 0.305 0.000
N73.9 Female pelvic inflammatory disease, unspecified
0.695 0.305 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.693 0.307 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.693 0.307 0.000
M94 Other disorders of cartilage
0.692 0.308 0.000
E13 Other specified diabetes mellitus
0.691 0.309 0.000
Chapter XXII Codes for special purposes
0.691 0.309 0.000
B15-B19 Viral hepatitis
0.691 0.309 0.000
O16 Unspecified maternal hypertension
0.690 0.310 0.000
O80 Single spontaneous delivery
0.690 0.310 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.687 0.313 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.687 0.313 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.685 0.314 0.000
S32 Fracture of lumbar spine and pelvis
0.685 0.315 0.000
C15-C26 Malignant neoplasms of digestive organs
0.685 0.315 0.000
M21 Other acquired deformities of limbs
0.685 0.315 0.000
E83.4 Disorders of magnesium metabolism
0.684 0.316 0.000
M15 Polyarthrosis
0.684 0.316 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.683 0.317 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.682 0.317 0.000
I73.0 Raynaud's syndrome
0.682 0.318 0.000
M87 Osteonecrosis
0.681 0.319 0.000
B35-B49 Mycoses
0.681 0.319 0.000
M16.0 Primary coxarthrosis, bilateral
0.681 0.319 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.680 0.319 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.680 0.320 0.000
E85.4 Organ-limited amyloidosis
0.680 0.320 0.000
I74 Arterial embolism and thrombosis
0.680 0.320 0.000
S29 Other and unspecified injuries of thorax
0.680 0.320 0.000
I49.8 Other specified cardiac arrhythmias
0.680 0.320 0.000
D50-D53 Nutritional anaemias
0.678 0.322 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.677 0.323 0.000
I00-I02 Acute rheumatic fever
0.676 0.323 0.000
N18.8 Other chronic renal failure
0.676 0.324 0.000
N18.1 Chronic kidney disease, stage 1
0.676 0.324 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.676 0.324 0.000
C90.0 Multiple myeloma
0.675 0.325 0.000
I35 Nonrheumatic aortic valve disorders
0.673 0.327 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.673 0.327 0.000
G41 Status epilepticus
0.672 0.327 0.000
S70-S79 Injuries to the hip and thigh
0.672 0.328 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.672 0.328 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.672 0.328 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.672 0.328 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.672 0.328 0.000
I77 Other disorders of arteries and arterioles
0.672 0.328 0.000
N76.8 Other specified inflammation of vagina and vulva
0.671 0.329 0.000
E12 Malnutrition-related diabetes mellitus
0.670 0.330 0.000
M24 Other specific joint derangements
0.669 0.331 0.000
M16.1 Other primary coxarthrosis
0.669 0.331 0.000
D55-D59 Haemolytic anaemias
0.669 0.331 0.000
D00-D09 In situ neoplasms
0.668 0.332 0.000
N76.4 Abscess of vulva
0.667 0.333 0.000
S61.8 Open wound of other parts of wrist and hand
0.666 0.333 0.000
O03 Spontaneous abortion
0.666 0.334 0.000
A08 Viral and other specified intestinal infections
0.666 0.334 0.000
V20-V29 Motorcycle rider injured in transport accident
0.665 0.334 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.665 0.335 0.000
C95 Leukaemia of unspecified cell type
0.665 0.335 0.000
C94 Other leukaemias of specified cell type
0.665 0.335 0.000
C93 Monocytic leukaemia
0.665 0.335 0.000
C88 Malignant immunoproliferative diseases
0.665 0.335 0.000
C86 Other specified types of T/NK-cell lymphoma
0.665 0.335 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.665 0.335 0.000
W25 Contact with sharp glass
0.665 0.335 0.000
M16.7 Other secondary coxarthrosis
0.664 0.336 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.664 0.336 0.000
M16.5 Other posttraumatic coxarthrosis
0.664 0.336 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.664 0.336 0.000
M16.3 Other dysplastic coxarthrosis
0.664 0.336 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.664 0.336 0.000
M88 Paget's disease of bone [osteitis deformans]
0.663 0.336 0.000
S61.1 Open wound of finger(s) with damage to nail
0.663 0.337 0.000
E27 Other disorders of adrenal gland
0.663 0.337 0.000
C51-C58 Malignant neoplasms of female genital organs
0.662 0.338 0.000
E04 Other non-toxic goitre
0.661 0.338 0.000
M80 Osteoporosis with pathological fracture
0.660 0.340 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.660 0.340 0.000
C65 Malignant neoplasm of renal pelvis
0.660 0.340 0.000
N43 Hydrocele and spermatocele
0.660 0.340 0.000
M20.2 Hallux rigidus
0.659 0.341 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.659 0.341 0.000
E83.8 Other disorders of mineral metabolism
0.659 0.341 0.000
E83.2 Disorders of zinc metabolism
0.659 0.341 0.000
E83.0 Disorders of copper metabolism
0.659 0.341 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.658 0.341 0.000
Y35-Y36 Legal intervention and operations of war
0.658 0.341 0.000
Y10-Y34 Event of undetermined intent
0.658 0.341 0.000
Y00-Y09 Assault
0.658 0.341 0.000
X85-X99 Assault
0.658 0.341 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.658 0.341 0.000
X50-X57 Overexertion, travel and privation
0.658 0.341 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.658 0.341 0.000
X30-X39 Exposure to forces of nature
0.658 0.341 0.000
X20-X29 Contact with venomous animals and plants
0.658 0.341 0.000
X10-X19 Contact with heat and hot substances
0.658 0.341 0.000
X00-X09 Exposure to smoke, fire and flames
0.658 0.341 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.658 0.341 0.000
W75-W84 Other accidental threats to breathing
0.658 0.341 0.000
W65-W74 Accidental drowning and submersion
0.658 0.341 0.000
W50-W64 Exposure to animate mechanical forces
0.658 0.341 0.000
V98-V99 Other and unspecified transport accidents
0.658 0.341 0.000
V95-V97 Air and space transport accidents
0.658 0.341 0.000
V90-V94 Water transport accidents
0.658 0.341 0.000
V80-V89 Other land transport accidents
0.658 0.341 0.000
V70-V79 Bus occupant injured in transport accident
0.658 0.341 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.658 0.341 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.658 0.341 0.000
V40-V49 Car occupant injured in transport accident
0.658 0.341 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.658 0.341 0.000
V01-V09 Pedestrian injured in transport accident
0.658 0.341 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.658 0.342 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.658 0.342 0.000
C92.1 Chronic myeloid leukaemia
0.658 0.342 0.000
S91 Open wound of ankle and foot
0.658 0.342 0.000
S00-S09 Injuries to the head
0.658 0.342 0.000
D45 Polycythaemia vera
0.657 0.343 0.000
M65 Synovitis and tenosynovitis
0.657 0.343 0.000
C67.4 Posterior wall of bladder
0.657 0.343 0.000
G30-G32 Other degenerative diseases of the nervous system
0.657 0.343 0.000
I33 Acute and subacute endocarditis
0.655 0.345 0.000
I49.5 Sick sinus syndrome
0.655 0.345 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.655 0.345 0.000
G43.9 Migraine, unspecified
0.654 0.346 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.653 0.346 0.000
O47 False labour
0.653 0.347 0.000
C67.3 Anterior wall of bladder
0.652 0.348 0.000
D30 Benign neoplasm of urinary organs
0.652 0.348 0.000
S64 Injury of nerves at wrist and hand level
0.651 0.349 0.000
I99 Other and unspecified disorders of circulatory system
0.651 0.349 0.000
S62.3 Fracture of other metacarpal bone
0.650 0.350 0.000
N02 Recurrent and persistent haematuria
0.649 0.351 0.000
D61 Other aplastic anaemias
0.647 0.353 0.000
M90 Osteopathies in diseases classified elsewhere
0.647 0.353 0.000
C85.1 B-cell lymphoma, unspecified
0.646 0.354 0.000
C81 Hodgkin's disease
0.645 0.355 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.645 0.355 0.000
O02 Other abnormal products of conception
0.644 0.356 0.000
M83 Adult osteomalacia
0.644 0.356 0.000
M82 Osteoporosis in diseases classified elsewhere
0.644 0.356 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.643 0.356 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.643 0.356 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.643 0.356 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.643 0.356 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.643 0.356 0.000
G20-G26 Extrapyramidal and movement disorders
0.643 0.357 0.000
N45 Orchitis and epididymitis
0.643 0.357 0.000
C67.6 Ureteric orifice
0.643 0.357 0.000
G40.9 Epilepsy, unspecified
0.642 0.358 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.641 0.359 0.000
A02 Other Salmonella infections
0.641 0.359 0.000
I49.4 Other and unspecified premature depolarisation
0.640 0.360 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.638 0.362 0.000
O07 Failed attempted abortion
0.638 0.362 0.000
O06 Unspecified abortion
0.638 0.362 0.000
O05 Other abortion
0.638 0.362 0.000
O01 Hydatidiform mole
0.638 0.362 0.000
O00 Ectopic pregnancy
0.638 0.362 0.000
N76.6 Ulceration of vulva
0.638 0.362 0.000
N76.5 Ulceration of vagina
0.638 0.362 0.000
N76.3 Subacute and chronic vulvitis
0.638 0.362 0.000
N76.2 Acute vulvitis
0.638 0.362 0.000
N76.1 Subacute and chronic vaginitis
0.638 0.362 0.000
N18.2 Chronic kidney disease, stage 2
0.637 0.362 0.000
C91.1 Chronic lymphocytic leukaemia
0.636 0.364 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.636 0.364 0.000
D11 Benign neoplasm of major salivary glands
0.635 0.365 0.000
S60 Superficial injury of wrist and hand
0.635 0.365 0.000
S27 Injury of other and unspecified intrathoracic organs
0.634 0.366 0.000
S69 Other and unspecified injuries of wrist and hand
0.634 0.366 0.000
S67 Crushing injury of wrist and hand
0.634 0.366 0.000
S65 Injury of blood vessels at wrist and hand level
0.634 0.366 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.633 0.367 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.633 0.367 0.000
M34 Systemic sclerosis
0.633 0.367 0.000
M33 Dermatopolymyositis
0.633 0.367 0.000
M32 Systemic lupus erythematosus
0.633 0.367 0.000
M30 Polyarteritis nodosa and related conditions
0.633 0.367 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.632 0.368 0.000
N42.3 Dysplasia of prostate
0.632 0.368 0.000
N42.1 Congestion and haemorrhage of prostate
0.632 0.368 0.000
N42.0 Calculus of prostate
0.632 0.368 0.000
D26 Other benign neoplasms of uterus
0.632 0.368 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.631 0.369 0.000
E10.3 With ophthalmic complications
0.631 0.369 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.631 0.369 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.630 0.370 0.000
O97 Death from sequelae of direct obstetric causes
0.630 0.370 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.630 0.370 0.000
O95 Obstetric death of unspecified cause
0.630 0.370 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.630 0.370 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.630 0.370 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.630 0.370 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.630 0.370 0.000
E89.5 Postprocedural testicular hypofunction
0.630 0.370 0.000
E89.4 Postprocedural ovarian failure
0.630 0.370 0.000
E89.3 Postprocedural hypopituitarism
0.630 0.370 0.000
E89.2 Postprocedural hypoparathyroidism
0.630 0.370 0.000
E89.1 Postprocedural hypoinsulinaemia
0.630 0.370 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.629 0.371 0.000
S37 Injury of urinary and pelvic organs
0.629 0.371 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.629 0.371 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.629 0.371 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.629 0.371 0.000
S31 Open wound of abdomen, lower back and pelvis
0.629 0.371 0.000
N17 Acute renal failure
0.629 0.371 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.629 0.371 0.000
I46 Cardiac arrest
0.629 0.371 0.000
M85 Other disorders of bone density and structure
0.629 0.371 0.000
B02 Zoster [herpes zoster]
0.628 0.372 0.000
O81 Single delivery by forceps and vacuum extractor
0.627 0.373 0.000
Y95 Nosocomial condition
0.626 0.373 0.000
T18 Foreign body in alimentary tract
0.626 0.374 0.000
S20 Superficial injury of thorax
0.625 0.375 0.000
T78 Adverse effects, not elsewhere classified
0.625 0.375 0.000
E50-E64 Other nutritional deficiencies
0.624 0.375 0.000
N48.9 Disorder of penis, unspecified
0.624 0.376 0.000
N48.5 Ulcer of penis
0.624 0.376 0.000
N48.4 Impotence of organic origin
0.624 0.376 0.000
N48.3 Priapism
0.624 0.376 0.000
N48.2 Other inflammatory disorders of penis
0.624 0.376 0.000
N48.0 Leukoplakia of penis
0.624 0.376 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.624 0.376 0.000
N75.0 Cyst of Bartholin's gland
0.623 0.377 0.000
I52 Other heart disorders in diseases classified elsewhere
0.623 0.377 0.000
I48 Atrial fibrillation and flutter
0.623 0.377 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.623 0.377 0.000
I41 Myocarditis in diseases classified elsewhere
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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