TreeWAS – Variant ID: rs35531140

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
M20-M25 Other joint disorders	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
M23 Internal derangement of knee	1.000	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.999	0.001
Chapter V Mental and behavioural disorders	0.999	0.001
Chapter XX External causes of morbidity and mortality	0.997	0.003
F30-F39 Mood [affective] disorders	0.994	0.006
M45-M49 Spondylopathies	0.985	0.015
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.984	0.016
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.981	0.019
F32 Depressive episode	0.980	0.020
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.977	0.023
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.975	0.025
F32.9 Depressive episode, unspecified	0.974	0.026
R06 Abnormalities of breathing	0.965	0.035
Chapter X Diseases of the respiratory system	0.963	0.037
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.955	0.045
J95-J99 Other diseases of the respiratory system	0.948	0.052
S80-S89 Injuries to the knee and lower leg	0.943	0.057
M47 Spondylosis	0.935	0.065
R06.5 Mouth breathing	0.935	0.065
M05-M14 Inflammatory polyarthropathies	0.932	0.068
S40-S49 Injuries to the shoulder and upper arm	0.929	0.071
J98 Other respiratory disorders	0.928	0.072
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.928	0.072
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.925	0.075
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.920	0.080
J98.1 Pulmonary collapse	0.918	0.082
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.915	0.085
R06.0 Dyspnoea	0.911	0.089
M15-M19 Arthrosis	0.910	0.090
Chapter VI Diseases of the nervous system	0.909	0.091
M50-M54 Other dorsopathies	0.902	0.098
R03 Abnormal blood-pressure reading, without diagnosis	0.901	0.099
S60-S69 Injuries to the wrist and hand	0.901	0.099
M48 Other spondylopathies	0.901	0.099
Chapter VIII Diseases of the ear and mastoid process	0.900	0.100
M25 Other joint disorders, not elsewhere classified	0.898	0.102
M17 Gonarthrosis [arthrosis of knee]	0.896	0.104
M23.3 Other meniscus derangements	0.888	0.112
T36-T50 Poisoning by drugs, medicaments and biological substances	0.886	0.114
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.885	0.115
M80-M85 Disorders of bone density and structure	0.884	0.116
M17.1 Other primary gonarthrosis	0.884	0.116
F10 Mental and behavioural disorders due to use of alcohol	0.882	0.118
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.881	0.119
M22 Disorders of patella	0.879	0.121
F33 Recurrent depressive disorder	0.877	0.123
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.872	0.128
M47.8 Other spondylosis	0.872	0.128
R01 Cardiac murmurs and other cardiac sounds	0.870	0.130
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.865	0.135
R03.1 Nonspecific low blood-pressure reading	0.861	0.139
F39 Unspecified mood [affective] disorder	0.859	0.141
F40-F48 Neurotic, stress-related and somatoform disorders	0.859	0.141
M13 Other arthritis	0.855	0.145
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.850	0.150
Chapter I Certain infectious and parasitic diseases	0.846	0.154
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.845	0.155
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.842	0.158
M48.0 Spinal stenosis	0.840	0.160
Chapter XXII Codes for special purposes	0.837	0.163
R21 Rash and other nonspecific skin eruption	0.835	0.165
F10.0 Acute intoxication	0.835	0.165
H65-H75 Diseases of middle ear and mastoid	0.825	0.175
S10-S19 Injuries to the neck	0.825	0.175
T85 Complications of other internal prosthetic devices, implants and grafts	0.825	0.175
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.824	0.176
M21 Other acquired deformities of limbs	0.824	0.176
S42 Fracture of shoulder and upper arm	0.822	0.178
M54 Dorsalgia	0.820	0.180
Y83.1 Surgical operation with implant of artificial internal device	0.817	0.183
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.815	0.185
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.812	0.188
W00-W19 Falls	0.812	0.188
J60-J70 Lung diseases due to external agents	0.812	0.188
R00 Abnormalities of heart beat	0.811	0.189
X60-X84 Intentional self-harm	0.809	0.191
S81 Open wound of lower leg	0.808	0.192
M25.7 Osteophyte	0.802	0.198
M13.9 Arthritis, unspecified	0.800	0.200
J95 Postprocedural respiratory disorders, not elsewhere classified	0.797	0.203
S70-S79 Injuries to the hip and thigh	0.796	0.204
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.796	0.204
R01.1 Cardiac murmur, unspecified	0.794	0.206
M23.8 Other internal derangements of knee	0.792	0.208
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.792	0.208
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.789	0.211
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.786	0.214
M47.86 Other spondylosis (Lumbar region)	0.784	0.216
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.783	0.217
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.783	0.217
S62 Fracture at wrist and hand level	0.777	0.223
G90-G99 Other disorders of the nervous system	0.775	0.225
M22.2 Patellofemoral disorders	0.775	0.225
M45 Ankylosing spondylitis	0.773	0.226
M91-M94 Chondropathies	0.773	0.227
R00.2 Palpitations	0.773	0.227
M48.06 Spinal stenosis (Lumbar region)	0.772	0.228
M17.3 Other posttraumatic gonarthrosis	0.772	0.228
M13.97 Arthritis, unspecified (Ankle and foot)	0.771	0.229
M65-M68 Disorders of synovium and tendon	0.769	0.231
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.769	0.231
S00-S09 Injuries to the head	0.769	0.231
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.767	0.233
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.766	0.234
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.766	0.234
S82 Fracture of lower leg, including ankle	0.764	0.236
G40-G47 Episodic and paroxysmal disorders	0.764	0.236
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.760	0.240
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.760	0.240
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.758	0.242
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.755	0.245
R07 Pain in throat and chest	0.754	0.246
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.752	0.248
R06.2 Wheezing	0.752	0.248
V20-V29 Motorcycle rider injured in transport accident	0.751	0.249
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.750	0.249
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.749	0.251
S90-S99 Injuries to the ankle and foot	0.749	0.251
T93 Sequelae of injuries of lower limb	0.749	0.251
M07 Psoriatic and enteropathic arthropathies	0.748	0.252
Y40 Systemic antibiotics	0.748	0.252
M23.6 Other spontaneous disruption of ligament(s) of knee	0.747	0.253
S49 Other and unspecified injuries of shoulder and upper arm	0.747	0.253
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.743	0.257
M25.6 Stiffness of joint, not elsewhere classified	0.743	0.257
J09-J18 Influenza and pneumonia	0.743	0.257
D50-D53 Nutritional anaemias	0.743	0.257
M24 Other specific joint derangements	0.742	0.258
F10.1 Harmful use	0.741	0.259
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.740	0.260
T86 Failure and rejection of transplanted organs and tissues	0.739	0.261
G70-G73 Diseases of myoneural junction and muscle	0.739	0.261
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.738	0.262
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.738	0.262
M47.87 Other spondylosis (Lumbosacral region)	0.738	0.262
M80 Osteoporosis with pathological fracture	0.737	0.263
M54.9 Dorsalgia, unspecified	0.737	0.263
T46 Poisoning by agents primarily affecting the cardiovascular system	0.736	0.264
Chapter XXI Factors influencing health status and contact with health services	0.735	0.265
S80 Superficial injury of lower leg	0.734	0.266
R80 Isolated proteinuria	0.733	0.267
T66-T78 Other and unspecified effects of external causes	0.733	0.267
M22.8 Other disorders of patella	0.733	0.267
M20 Acquired deformities of fingers and toes	0.732	0.268
V10-V19 Pedal cyclist injured in transport accident	0.732	0.268
Y51 Drugs primarily affecting the autonomic nervous system	0.732	0.268
M84 Disorders of continuity of bone	0.732	0.268
R44 Other symptoms and signs involving general sensations and perceptions	0.731	0.268
G50-G59 Nerve, nerve root and plexus disorders	0.731	0.269
M47.1 Other spondylosis with myelopathy	0.730	0.270
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.730	0.270
F33.9 Recurrent depressive disorder, unspecified	0.728	0.271
J98.9 Respiratory disorder, unspecified	0.728	0.272
W20-W49 Exposure to inanimate mechanical forces	0.727	0.273
M23.5 Chronic instability of knee	0.726	0.274
T79-T79 Certain early complications of trauma	0.725	0.275
M31 Other necrotising vasculopathies	0.725	0.275
S69 Other and unspecified injuries of wrist and hand	0.725	0.275
H66 Suppurative and unspecified otitis media	0.724	0.276
H80-H83 Diseases of inner ear	0.723	0.277
F60-F69 Disorders of adult personality and behaviour	0.723	0.277
F32.0 Mild depressive episode	0.723	0.277
Y84.6 Urinary catheterisation	0.723	0.277
S64 Injury of nerves at wrist and hand level	0.721	0.279
M46 Other inflammatory spondylopathies	0.720	0.280
T80 Complications following infusion, transfusion and therapeutic injection	0.718	0.282
M25.76 Osteophyte (Lower leg)	0.717	0.282
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M34 Systemic sclerosis	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
M30 Polyarteritis nodosa and related conditions	0.717	0.283
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
M23.9 Internal derangement of knee, unspecified	0.717	0.283
M23.4 Loose body in knee	0.717	0.283
M23.1 Discoid meniscus (congenital)	0.717	0.283
M23.0 Cystic meniscus	0.717	0.283
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.716	0.283
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.716	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.284
F70-F79 Mental retardation	0.716	0.284
F80-F89 Disorders of psychological development	0.716	0.284
T15-T19 Effects of foreign body entering through natural orifice	0.715	0.285
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.714	0.285
Y35-Y36 Legal intervention and operations of war	0.714	0.285
Y10-Y34 Event of undetermined intent	0.714	0.285
Y00-Y09 Assault	0.714	0.285
X85-X99 Assault	0.714	0.285
X58-X59 Accidental exposure to other and unspecified factors	0.714	0.285
X50-X57 Overexertion, travel and privation	0.714	0.285
X40-X49 Accidental poisoning by and exposure to noxious substances	0.714	0.285
X30-X39 Exposure to forces of nature	0.714	0.285
X20-X29 Contact with venomous animals and plants	0.714	0.285
X10-X19 Contact with heat and hot substances	0.714	0.285
X00-X09 Exposure to smoke, fire and flames	0.714	0.285
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.714	0.285
W75-W84 Other accidental threats to breathing	0.714	0.285
W65-W74 Accidental drowning and submersion	0.714	0.285
W50-W64 Exposure to animate mechanical forces	0.714	0.285
V98-V99 Other and unspecified transport accidents	0.714	0.285
V95-V97 Air and space transport accidents	0.714	0.285
V90-V94 Water transport accidents	0.714	0.285
V80-V89 Other land transport accidents	0.714	0.285
V70-V79 Bus occupant injured in transport accident	0.714	0.285
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.714	0.285
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.714	0.285
V40-V49 Car occupant injured in transport accident	0.714	0.285
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.714	0.285
V01-V09 Pedestrian injured in transport accident	0.714	0.285
M47.9 Spondylosis, unspecified	0.714	0.286
F38 Other mood [affective] disorders	0.713	0.287
F34 Persistent mood [affective] disorders	0.713	0.287
F30 Manic episode	0.713	0.287
B15-B19 Viral hepatitis	0.711	0.289
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.711	0.289
G40 Epilepsy	0.710	0.290
R02 Gangrene, not elsewhere classified	0.709	0.291
Y83.4 Other reconstructive surgery	0.709	0.291
M47.2 Other spondylosis with radiculopathy	0.708	0.292
F40 Phobic anxiety disorders	0.706	0.294
M49 Spondylopathies in diseases classified elsewhere	0.706	0.294
F99-F99 Unspecified mental disorder	0.706	0.294
B07 Viral warts	0.706	0.294
M25.8 Other specified joint disorders	0.706	0.294
Y52 Agents primarily affecting the cardiovascular system	0.705	0.295
S20-S29 Injuries to the thorax	0.704	0.296
F32.8 Other depressive episodes	0.703	0.297
M48.07 Spinal stenosis (Lumbosacral region)	0.701	0.299
R07.2 Precordial pain	0.701	0.299
R95-R99 Ill-defined and unknown causes of mortality	0.700	0.300
G30-G32 Other degenerative diseases of the nervous system	0.700	0.300
Y60-Y69 Misadventures to patients during surgical and medical care	0.699	0.301
M13.96 Arthritis, unspecified (Lower leg)	0.697	0.303
J40-J47 Chronic lower respiratory diseases	0.696	0.304
S62.6 Fracture of other finger	0.696	0.304
D80-D89 Certain disorders involving the immune mechanism	0.694	0.305
D68 Other coagulation defects	0.694	0.306
Y41 Other systemic anti-infectives and antiparasitics	0.694	0.306
Y84.0 Cardiac catheterisation	0.693	0.307
M86-M90 Other osteopathies	0.692	0.308
M85 Other disorders of bone density and structure	0.692	0.308
R06.7 Sneezing	0.691	0.308
R06.6 Hiccough	0.691	0.308
R06.3 Periodic breathing	0.691	0.308
R06.1 Stridor	0.691	0.308
M06 Other rheumatoid arthritis	0.691	0.309
S68 Traumatic amputation of wrist and hand	0.690	0.310
S42.3 Fracture of shaft of humerus	0.689	0.311
M11 Other crystal arthropathies	0.687	0.313
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.685	0.315
M10 Gout	0.685	0.315
H71 Cholesteatoma of middle ear	0.683	0.316
Y83.2 Surgical operation with anastomosis, bypass or graft	0.683	0.317
Y84.4 Aspiration of fluid	0.683	0.317
Y83.5 Amputation of limb(s)	0.682	0.318
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.681	0.318
M50 Cervical disk disorders	0.680	0.320
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.680	0.320
Y95 Nosocomial condition	0.680	0.320
J99 Respiratory disorders in diseases classified elsewhere	0.679	0.320
J96 Respiratory failure, not elsewhere classified	0.679	0.320
T92 Sequelae of injuries of upper limb	0.679	0.321
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.677	0.323
S89 Other and unspecified injuries of lower leg	0.676	0.324
S88 Traumatic amputation of lower leg	0.676	0.324
S87 Crushing injury of lower leg	0.676	0.324
S86 Injury of muscle and tendon at lower leg level	0.676	0.324
S85 Injury of blood vessels at lower leg level	0.676	0.324
S84 Injury of nerves at lower leg level	0.676	0.324
S81.0 Open wound of knee	0.675	0.325
T88 Other complications of surgical and medical care, not elsewhere classified	0.675	0.325
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.673	0.327
H60-H62 Diseases of external ear	0.673	0.327
Y57 Other and unspecified drugs and medicaments	0.673	0.327
Y83.9 Surgical procedure, unspecified	0.672	0.328
M47.0 Anterior spinal and vertebral artery compression syndromes	0.671	0.329
M14 Arthropathies in other diseases classified elsewhere	0.668	0.332
M12 Other specific arthropathies	0.668	0.332
M09 Juvenile arthritis in diseases classified elsewhere	0.668	0.332
M08 Juvenile arthritis	0.668	0.332
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.667	0.332
J90-J94 Other diseases of pleura	0.667	0.333
S48 Traumatic amputation of shoulder and upper arm	0.666	0.334
S46 Injury of muscle and tendon at shoulder and upper arm level	0.666	0.334
S45 Injury of blood vessels at shoulder and upper arm level	0.666	0.334
S44 Injury of nerves at shoulder and upper arm level	0.666	0.334
S41 Open wound of shoulder and upper arm	0.666	0.334
S47 Crushing injury of shoulder and upper arm	0.666	0.334
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.666	0.334
J98.6 Disorders of diaphragm	0.665	0.335
J98.5 Diseases of mediastinum, not elsewhere classified	0.665	0.335
J98.3 Compensatory emphysema	0.665	0.335
J98.2 Interstitial emphysema	0.665	0.335
S42.9 Fracture of shoulder girdle, part unspecified	0.664	0.335
F32.3 Severe depressive episode with psychotic symptoms	0.664	0.336
T87 Complications peculiar to reattachment and amputation	0.663	0.337
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.663	0.337
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.663	0.337
A30-A49 Other bacterial diseases	0.663	0.337
G35-G37 Demyelinating diseases of the central nervous system	0.662	0.338
M21.0 Valgus deformity, not elsewhere classified	0.662	0.338
R81 Glycosuria	0.661	0.339
R06.4 Hyperventilation	0.660	0.339
J69 Pneumonitis due to solids and liquids	0.660	0.340
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.660	0.340
F18 Mental and behavioural disorders due to use of volatile solvents	0.660	0.340
F16 Mental and behavioural disorders due to use of hallucinogens	0.660	0.340
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.660	0.340
F14 Mental and behavioural disorders due to use of cocaine	0.660	0.340
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.660	0.340
F12 Mental and behavioural disorders due to use of cannabinoids	0.660	0.340
F11 Mental and behavioural disorders due to use of opioids	0.660	0.340
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.658	0.342
Z00-Z13 Persons encountering health services for examination and investigation	0.658	0.342
Y45.0 Opioids and related analgesics	0.657	0.343
F32.1 Moderate depressive episode	0.656	0.344
Y59 Other and unspecified vaccines and biological substances	0.656	0.344
Y58 Bacterial vaccines	0.656	0.344
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.656	0.344
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.656	0.344
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.656	0.344
Y53 Agents primarily affecting the gastro-intestinal system	0.656	0.344
Y50 Central nervous system stimulants, not elsewhere classified	0.656	0.344
Y49 Psychotropic drugs, not elsewhere classified	0.656	0.344
Y48 Anaesthetics and therapeutic gases	0.656	0.344
Y47 Sedatives, hypnotics and antianxiety drugs	0.656	0.344
Y46 Antiepileptics and anti-Parkinsonism drugs	0.656	0.344
M23.30 Other meniscus derangements (Multiple sites)	0.656	0.344
F20 Schizophrenia	0.655	0.345
S10 Superficial injury of neck	0.655	0.345
T43.2 Other and unspecified antidepressants	0.655	0.345
F43 Reaction to severe stress, and adjustment disorders	0.655	0.345
M21.2 Flexion deformity	0.655	0.345
S19 Other and unspecified injuries of neck	0.654	0.346
M51 Other intervertebral disk disorders	0.654	0.346
M15 Polyarthrosis	0.652	0.347
D70-D77 Other diseases of blood and blood-forming organs	0.652	0.348
G00-G09 Inflammatory diseases of the central nervous system	0.652	0.348
Q80-Q89 Other congenital malformations	0.651	0.348
W06 Fall involving bed	0.651	0.348
H74 Other disorders of middle ear and mastoid	0.650	0.350
M40-M43 Deforming dorsopathies	0.650	0.350
J98.0 Diseases of bronchus, not elsewhere classified	0.649	0.350
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.649	0.351
F41 Other anxiety disorders	0.649	0.351
H73 Other disorders of tympanic membrane	0.648	0.352
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.648	0.352
M53 Other dorsopathies, not elsewhere classified	0.647	0.353
Chapter IV Endocrine, nutritional and metabolic diseases	0.647	0.353
Y83.0 Surgical operation with transplant of whole organ	0.646	0.353
J98.8 Other specified respiratory disorders	0.646	0.353
S40 Superficial injury of shoulder and upper arm	0.646	0.354
S67 Crushing injury of wrist and hand	0.646	0.354
S65 Injury of blood vessels at wrist and hand level	0.646	0.354
M48.9 Spondylopathy, unspecified	0.646	0.354
M48.8 Other specified spondylopathies	0.646	0.354
M48.5 Collapsed vertebra, not elsewhere classified	0.646	0.354
M48.4 Fatigue fracture of vertebra	0.646	0.354
M48.3 Traumatic spondylopathy	0.646	0.354
M48.2 Kissing spine	0.646	0.354
M48.1 Ankylosing hyperostosis [Forestier]	0.646	0.354
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.645	0.355
W10 Fall on and from stairs and steps	0.645	0.355
S62.61 Fracture of other finger (open)	0.645	0.355
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.644	0.356
J15 Bacterial pneumonia, not elsewhere classified	0.644	0.356
M47.80 Other spondylosis (Multiple sites in spine)	0.644	0.356
M25.9 Joint disorder, unspecified	0.644	0.356
M25.3 Other instability of joint	0.644	0.356
M25.2 Flail joint	0.644	0.356
M25.1 Fistula of joint	0.644	0.356
M25.0 Haemarthrosis	0.644	0.356
F10.2 Dependence syndrome	0.643	0.357
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.643	0.357
M17.5 Other secondary gonarthrosis	0.642	0.358
M17.4 Other secondary gonarthrosis, bilateral	0.642	0.358
M17.2 Posttraumatic gonarthrosis, bilateral	0.642	0.358
J95.0 Tracheostomy malfunction	0.642	0.358
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.642	0.358
D50 Iron deficiency anaemia	0.640	0.360
M70-M79 Other soft tissue disorders	0.639	0.360
J95.8 Other postprocedural respiratory disorders	0.639	0.361
F31 Bipolar affective disorder	0.639	0.361
S43.0 Dislocation of shoulder joint	0.639	0.361
J30-J39 Other diseases of upper respiratory tract	0.638	0.362
T90 Sequelae of injuries of head	0.638	0.362
S61 Open wound of wrist and hand	0.638	0.362
M13.91 Arthritis, unspecified (Shoulder region)	0.637	0.363
F42 Obsessive-compulsive disorder	0.637	0.363
M23.37 Other meniscus derangements-Capsular lig	0.636	0.364
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.636	0.364
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.636	0.364
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.636	0.364
W18 Other fall on same level	0.636	0.364
B35-B49 Mycoses	0.635	0.365
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.635	0.365
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.635	0.365
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.635	0.365
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.635	0.365
T41 Poisoning by anaesthetics and therapeutic gases	0.635	0.365
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.635	0.365
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.635	0.365
T36 Poisoning by systemic antibiotics	0.635	0.365
Y43 Primarily systemic agents	0.635	0.365
D55-D59 Haemolytic anaemias	0.634	0.366
M05 Seropositive rheumatoid arthritis	0.634	0.366
M83 Adult osteomalacia	0.634	0.366
M82 Osteoporosis in diseases classified elsewhere	0.634	0.366
S42.2 Fracture of upper end of humerus	0.633	0.367
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.633	0.367
F10.9 Unspecified mental and behavioural disorder	0.632	0.368
F10.8 Other mental and behavioural disorders	0.632	0.368
F10.7 Residual and late-onset psychotic disorder	0.632	0.368
F10.6 Amnesic syndrome	0.632	0.368
F10.5 Psychotic disorder	0.632	0.368
F10.4 Withdrawal state with delirium	0.632	0.368
M54.99 Dorsalgia, unspecified (Site unspecified)	0.632	0.368
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.632	0.368
S82.3 Fracture of lower end of tibia	0.632	0.368
M54.2 Cervicalgia	0.632	0.368
M54.5 Low back pain	0.632	0.368
M80.9 Unspecified osteoporosis with pathological fracture	0.632	0.368
S72 Fracture of femur	0.631	0.369
M22.1 Recurrent subluxation of patella	0.630	0.369
M22.9 Disorder of patella, unspecified	0.630	0.369
M22.3 Other derangements of patella	0.630	0.369
M22.0 Recurrent dislocation of patella	0.630	0.369
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.630	0.370
S42.4 Fracture of lower end of humerus	0.629	0.371
F33.8 Other recurrent depressive disorders	0.629	0.371
F33.4 Recurrent depressive disorder, currently in remission	0.629	0.371
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.629	0.371
F33.0 Recurrent depressive disorder, current episode mild	0.629	0.371
M47.82 Other spondylosis (Cervical region)	0.628	0.372
T46.4 Angiotensin-converting-enzyme inhibitors	0.628	0.372
M20.5 Other deformities of toe(s) (acquired)	0.626	0.374
F33.1 Recurrent depressive disorder, current episode moderate	0.626	0.374
S81.8 Open wound of other parts of lower leg	0.626	0.374
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.626	0.374
T98 Sequelae of other and unspecified effects of external causes	0.625	0.375
T95 Sequelae of burns, corrosions and frostbite	0.625	0.375
T94 Sequelae of injuries involving multiple and unspecified body regions	0.625	0.375
T91 Sequelae of injuries of neck and trunk	0.625	0.375
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.625	0.375
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.625	0.375
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.625	0.375
M47.85 Other spondylosis (Thoracolumbar region)	0.625	0.375
M47.84 Other spondylosis (Thoracic region)	0.625	0.375
M47.83 Other spondylosis (Cervicothoracic region)	0.625	0.375
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.625	0.375
Z09.8 Follow-up examination after other treatment for other conditions	0.625	0.375
G40.9 Epilepsy, unspecified	0.624	0.376
Y83.3 Surgical operation with formation of external stoma	0.624	0.376
R01.2 Other cardiac sounds	0.624	0.376
R01.0 Benign and innocent cardiac murmurs	0.624	0.376
F25 Schizoaffective disorders	0.623	0.376
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.623	0.377
R42 Dizziness and giddiness	0.622	0.378
M45.X9 Ankylosing spondylitis (Site unspecified)	0.622	0.378
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.622	0.378
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.621	0.379
S02 Fracture of skull and facial bones	0.617	0.383
G70 Myasthenia gravis and other myoneural disorders	0.617	0.383
M66 Spontaneous rupture of synovium and tendon	0.616	0.383
S49.9 Unspecified injury of shoulder and upper arm	0.617	0.383
M07.3 Other psoriatic arthropathies	0.616	0.384
T43.0 Tricyclic and tetracyclic antidepressants	0.616	0.384
F48 Other neurotic disorders	0.616	0.384
F45 Somatoform disorders	0.616	0.384
F44 Dissociative [conversion] disorders	0.616	0.384
S60 Superficial injury of wrist and hand	0.615	0.385
W07 Fall involving chair	0.615	0.385
J44 Other chronic obstructive pulmonary disease	0.615	0.385
D69 Purpura and other haemorrhagic conditions	0.614	0.386
B18 Chronic viral hepatitis	0.614	0.386
Y44 Agents primarily affecting blood constituents	0.614	0.386
Y40.8 Other systemic antibiotics	0.614	0.386
M84.1 Nonunion of fracture [pseudarthrosis]	0.614	0.386
T43.3 Phenothiazine antipsychotics and neuroleptics	0.614	0.386
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.614	0.386
S83.6 Sprain and strain of other and unspecified parts of knee	0.613	0.387
S82.2 Fracture of shaft of tibia	0.613	0.387
M13.8 Other specified arthritis	0.613	0.387
M13.1 Monoarthritis, not elsewhere classified	0.613	0.387
M13.0 Polyarthritis, unspecified	0.613	0.387
M48.02 Spinal stenosis (Cervical region)	0.613	0.387
M47.89 Other spondylosis (Site unspecified)	0.612	0.388
D52 Folate deficiency anaemia	0.611	0.389

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations