TreeWAS – Variant ID: rs35638776

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
I25 Chronic ischaemic heart disease	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
E70-E90 Metabolic disorders	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.999	0.001
I25.9 Chronic ischaemic heart disease, unspecified	0.999	0.001
E78.0 Pure hypercholesterolaemia	0.999	0.001
I25.2 Old myocardial infarction	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
Chapter V Mental and behavioural disorders	0.999	0.001
I30-I52 Other forms of heart disease	0.998	0.002
Chapter XIV Diseases of the genitourinary system	0.997	0.003
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.995	0.005
Chapter XI Diseases of the digestive system	0.991	0.009
K20-K31 Diseases of oesophagus, stomach and duodenum	0.990	0.010
I21 Acute myocardial infarction	0.989	0.011
E10-E14 Diabetes mellitus	0.987	0.013
I20 Angina pectoris	0.987	0.013
N17-N19 Renal failure	0.986	0.014
K22 Other diseases of oesophagus	0.985	0.015
I21.9 Acute myocardial infarction, unspecified	0.985	0.015
O60-O75 Complications of labour and delivery	0.983	0.017
I95-I99 Other and unspecified disorders of the circulatory system	0.982	0.018
N20-N23 Urolithiasis	0.981	0.019
N10-N16 Renal tubulo-interstitial diseases	0.976	0.024
F30-F39 Mood [affective] disorders	0.974	0.026
N20 Calculus of kidney and ureter	0.973	0.027
E83 Disorders of mineral metabolism	0.973	0.027
I20.9 Angina pectoris, unspecified	0.973	0.027
N20.1 Calculus of ureter	0.970	0.030
Z40-Z54 Persons encountering health services for specific procedures and health care	0.970	0.030
I25.8 Other forms of chronic ischaemic heart disease	0.968	0.032
I95 Hypotension	0.968	0.032
K31 Other diseases of stomach and duodenum	0.967	0.033
I49 Other cardiac arrhythmias	0.966	0.034
M20-M25 Other joint disorders	0.965	0.035
Z00-Z13 Persons encountering health services for examination and investigation	0.965	0.035
N18 Chronic renal failure	0.964	0.036
E11 Non-insulin-dependent diabetes mellitus	0.959	0.041
Z50 Care involving use of rehabilitation procedures	0.955	0.045
N13 Obstructive and reflux uropathy	0.951	0.049
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.949	0.051
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.943	0.057
E83.5 Disorders of calcium metabolism	0.942	0.058
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.940	0.060
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.938	0.062
I49.9 Cardiac arrhythmia, unspecified	0.937	0.063
Z45 Adjustment and management of implanted device	0.937	0.063
I95.9 Hypotension, unspecified	0.937	0.063
Z03 Medical observation and evaluation for suspected diseases and conditions	0.935	0.065
K22.7 Barrett's oesophagus	0.935	0.065
I60-I69 Cerebrovascular diseases	0.933	0.067
E10 Insulin-dependent diabetes mellitus	0.932	0.068
Z08 Follow-up examination after treatment for malignant neoplasm	0.932	0.068
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.932	0.068
S60-S69 Injuries to the wrist and hand	0.931	0.069
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.928	0.072
I70-I79 Diseases of arteries, arterioles and capillaries	0.926	0.074
E11.9 Without complications	0.926	0.074
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.924	0.076
Chapter I Certain infectious and parasitic diseases	0.923	0.077
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.922	0.078
M80-M85 Disorders of bone density and structure	0.920	0.080
N18.9 Chronic renal failure, unspecified	0.918	0.082
K22.9 Disease of oesophagus, unspecified	0.918	0.082
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.916	0.084
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.915	0.085
F31 Bipolar affective disorder	0.913	0.087
M20 Acquired deformities of fingers and toes	0.909	0.091
O94-O99 Other obstetric conditions, not elsewhere classified	0.907	0.093
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.907	0.093
K22.2 Oesophageal obstruction	0.901	0.099
Z03.4 Observation for suspected myocardial infarction	0.899	0.101
I25.1 Atherosclerotic heart disease	0.898	0.102
Z36 Antenatal screening	0.897	0.103
I47 Paroxysmal tachycardia	0.896	0.104
Z95 Presence of cardiac and vascular implants and grafts	0.896	0.104
Z60 Problems related to social environment	0.893	0.107
Chapter VI Diseases of the nervous system	0.892	0.108
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.888	0.112
O72 Postpartum haemorrhage	0.883	0.117
F33 Recurrent depressive disorder	0.882	0.118
K31.8 Other specified diseases of stomach and duodenum	0.881	0.119
I26 Pulmonary embolism	0.880	0.120
Z91 Personal history of risk-factors, not elsewhere classified	0.879	0.121
I67 Other cerebrovascular diseases	0.878	0.122
A30-A49 Other bacterial diseases	0.876	0.124
I80 Phlebitis and thrombophlebitis	0.872	0.128
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.871	0.129
N18.4 Chronic kidney disease, stage 4	0.871	0.129
K31.7 Polyp of stomach and duodenum	0.871	0.129
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.868	0.132
Z95.1 Presence of aortocoronary bypass graft	0.868	0.132
Chapter XII Diseases of the skin and subcutaneous tissue	0.867	0.133
M23 Internal derangement of knee	0.867	0.133
I50 Heart failure	0.866	0.134
I45 Other conduction disorders	0.865	0.135
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.865	0.135
F10 Mental and behavioural disorders due to use of alcohol	0.863	0.137
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.860	0.140
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.859	0.141
R07 Pain in throat and chest	0.859	0.141
I73 Other peripheral vascular diseases	0.858	0.142
O00-O08 Pregnancy with abortive outcome	0.858	0.142
Z50.1 Other physical therapy	0.858	0.142
R07.4 Chest pain, unspecified	0.858	0.142
M50-M54 Other dorsopathies	0.857	0.143
M20.5 Other deformities of toe(s) (acquired)	0.857	0.143
K50-K52 Noninfective enteritis and colitis	0.857	0.143
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.855	0.145
T36-T50 Poisoning by drugs, medicaments and biological substances	0.855	0.145
Z60.2 Living alone	0.854	0.146
N13.9 Obstructive and reflux uropathy, unspecified	0.853	0.147
M05-M14 Inflammatory polyarthropathies	0.852	0.148
M23.3 Other meniscus derangements	0.849	0.151
S80-S89 Injuries to the knee and lower leg	0.848	0.152
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.847	0.153
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.843	0.157
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.843	0.157
I22 Subsequent myocardial infarction	0.843	0.157
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.841	0.159
Z36.8 Other antenatal screening	0.841	0.159
I20.1 Angina pectoris with documented spasm	0.841	0.159
I44 Atrioventricular and left bundle-branch block	0.840	0.160
Z45.0 Adjustment and management of cardiac pacemaker	0.840	0.160
E83.4 Disorders of magnesium metabolism	0.839	0.161
I95.1 Orthostatic hypotension	0.834	0.166
A41 Other septicaemia	0.831	0.169
F00-F09 Organic, including symptomatic, mental disorders	0.830	0.170
F40-F48 Neurotic, stress-related and somatoform disorders	0.830	0.170
Z95.5 Presence of coronary angioplasty implant and graft	0.830	0.170
K11 Diseases of salivary glands	0.827	0.173
N19 Unspecified renal failure	0.827	0.173
K26 Duodenal ulcer	0.826	0.174
F10.2 Dependence syndrome	0.825	0.175
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.823	0.176
O68 Labour and delivery complicated by foetal stress [distress]	0.823	0.177
I67.9 Cerebrovascular disease, unspecified	0.823	0.177
E11.3 With ophthalmic complications	0.822	0.178
O16 Unspecified maternal hypertension	0.821	0.179
M80 Osteoporosis with pathological fracture	0.821	0.179
Z45.2 Adjustment and management of vascular access device	0.819	0.181
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.819	0.181
F31.9 Bipolar affective disorder, unspecified	0.818	0.182
Z39 Postpartum care and examination	0.817	0.183
N00-N08 Glomerular diseases	0.816	0.184
N17 Acute renal failure	0.815	0.185
I47.1 Supraventricular tachycardia	0.814	0.186
S66 Injury of muscle and tendon at wrist and hand level	0.814	0.186
S20-S29 Injuries to the thorax	0.807	0.193
E50-E64 Other nutritional deficiencies	0.806	0.194
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.806	0.194
K30 Dyspepsia	0.805	0.195
S40-S49 Injuries to the shoulder and upper arm	0.804	0.196
I25.5 Ischaemic cardiomyopathy	0.804	0.196
I35 Nonrheumatic aortic valve disorders	0.803	0.197
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.800	0.200
I38 Endocarditis, valve unspecified	0.800	0.200
O64 Obstructed labour due to malposition and malpresentation of foetus	0.798	0.202
I21.2 Acute transmural myocardial infarction of other sites	0.797	0.203
Z45.8 Adjustment and management of other implanted devices	0.797	0.203
F99-F99 Unspecified mental disorder	0.795	0.205
F31.0 Bipolar affective disorder, current episode hypomanic	0.795	0.205
T84.0 Mechanical complication of internal joint prosthesis	0.795	0.205
E20-E35 Disorders of other endocrine glands	0.792	0.208
O72.1 Other immediate postpartum haemorrhage	0.792	0.208
I73.9 Peripheral vascular disease, unspecified	0.790	0.210
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.789	0.210
T66-T78 Other and unspecified effects of external causes	0.789	0.211
Z96 Presence of other functional implants	0.787	0.213
F60-F69 Disorders of adult personality and behaviour	0.785	0.215
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.784	0.216
Z13 Special screening examination for other diseases and disorders	0.782	0.218
I95.2 Hypotension due to drugs	0.782	0.218
I45.1 Other and unspecified right bundle-branch block	0.782	0.218
O04 Medical abortion	0.782	0.218
E78.2 Mixed hyperlipidaemia	0.780	0.220
R01 Cardiac murmurs and other cardiac sounds	0.779	0.221
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.779	0.221
Z91.5 Personal history of self-harm	0.777	0.223
E10.1 With ketoacidosis	0.777	0.223
I81 Portal vein thrombosis	0.776	0.224
E10.9 Without complications	0.776	0.224
S00-S09 Injuries to the head	0.776	0.224
O32 Maternal care for known or suspected malpresentation of foetus	0.775	0.225
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.775	0.225
I50.9 Heart failure, unspecified	0.775	0.225
I49.3 Ventricular premature depolarisation	0.774	0.226
Chapter XX External causes of morbidity and mortality	0.774	0.226
S10-S19 Injuries to the neck	0.774	0.226
O69 Labour and delivery complicated by umbilical cord complications	0.773	0.227
T85 Complications of other internal prosthetic devices, implants and grafts	0.772	0.228
O34 Maternal care for known or suspected abnormality of pelvic organs	0.772	0.228
K25 Gastric ulcer	0.771	0.228
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.771	0.229
K31.9 Disease of stomach and duodenum, unspecified	0.771	0.229
Z57 Occupational exposure to risk-factors	0.771	0.229
O63 Long labour	0.771	0.229
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.771	0.229
N70-N77 Inflammatory diseases of female pelvic organs	0.771	0.229
M06 Other rheumatoid arthritis	0.770	0.230
M21 Other acquired deformities of limbs	0.770	0.230
Z52 Donors of organs and tissues	0.768	0.232
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.767	0.232
F33.9 Recurrent depressive disorder, unspecified	0.765	0.235
O42 Premature rupture of membranes	0.764	0.236
E10.4 With neurological complications	0.763	0.237
I20.0 Unstable angina	0.763	0.237
Z92 Personal history of medical treatment	0.762	0.238
Z34 Supervision of normal pregnancy	0.762	0.238
K11.5 Sialolithiasis	0.761	0.239
S70-S79 Injuries to the hip and thigh	0.761	0.239
O43 Placental disorders	0.759	0.241
M86-M90 Other osteopathies	0.759	0.241
K31.5 Obstruction of duodenum	0.759	0.241
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.759	0.241
Z54 Convalescence	0.758	0.242
M45-M49 Spondylopathies	0.758	0.242
G90-G99 Other disorders of the nervous system	0.757	0.243
Z03.1 Observation for suspected malignant neoplasm	0.757	0.243
N20.2 Calculus of kidney with calculus of ureter	0.757	0.243
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.756	0.244
O70 Perineal laceration during delivery	0.755	0.245
E10.3 With ophthalmic complications	0.754	0.246
Z50.8 Care involving use of rehabilitation procedures	0.754	0.246
K05 Gingivitis and periodontal diseases	0.754	0.246
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.753	0.247
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.752	0.248
I49.1 Atrial premature depolarisation	0.751	0.249
Z02 Examination and encounter for administrative purposes	0.751	0.249
M84 Disorders of continuity of bone	0.751	0.249
K52 Other non-infective gastro-enteritis and colitis	0.751	0.249
E78.5 Hyperlipidaemia, unspecified	0.750	0.250
I86 Varicose veins of other sites	0.750	0.250
M20.2 Hallux rigidus	0.750	0.250
N13.4 Hydroureter	0.748	0.252
Z89 Acquired absence of limb	0.746	0.254
Chapter XXII Codes for special purposes	0.746	0.254
S62 Fracture at wrist and hand level	0.746	0.254
L00-L08 Infections of the skin and subcutaneous tissue	0.745	0.255
O47 False labour	0.744	0.256
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.743	0.257
O66 Other obstructed labour	0.742	0.257
I33 Acute and subacute endocarditis	0.742	0.258
T88 Other complications of surgical and medical care, not elsewhere classified	0.742	0.258
R07.3 Other chest pain	0.741	0.259
Z82.3 Family history of stroke	0.740	0.260
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.740	0.260
O62 Abnormalities of forces of labour	0.738	0.262
I10-I15 Hypertensive diseases	0.737	0.263
I77 Other disorders of arteries and arterioles	0.737	0.263
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.736	0.264
M22 Disorders of patella	0.736	0.264
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.736	0.264
Z03.3 Observation for suspected nervous system disorder	0.736	0.264
T80 Complications following infusion, transfusion and therapeutic injection	0.735	0.265
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.734	0.266
A41.9 Septicaemia, unspecified	0.734	0.266
M20.1 Hallux valgus (acquired)	0.733	0.267
M65-M68 Disorders of synovium and tendon	0.732	0.268
I46 Cardiac arrest	0.732	0.268
O75 Other complications of labour and delivery, not elsewhere classified	0.731	0.269
Z91.6 Personal history of other physical trauma	0.731	0.269
E89.0 Postprocedural hypothyroidism	0.731	0.269
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.730	0.270
L50-L54 Urticaria and erythema	0.729	0.271
I51 Complications and ill-defined descriptions of heart disease	0.729	0.271
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.729	0.271
K70-K77 Diseases of liver	0.728	0.272
F32 Depressive episode	0.728	0.272
Z96.6 Presence of orthopaedic joint implants	0.727	0.273
S90-S99 Injuries to the ankle and foot	0.727	0.273
O04.9 Complete or unspecified, without complication	0.727	0.273
Z70-Z76 Persons encountering health services in other circumstances	0.727	0.273
M54 Dorsalgia	0.725	0.275
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.725	0.275
K26.3 Acute without haemorrhage or perforation	0.724	0.276
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.724	0.276
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.724	0.276
Z32 Pregnancy examination and test	0.724	0.276
I98 Other disorders of circulatory system in diseases classified elsewhere	0.723	0.277
M80.9 Unspecified osteoporosis with pathological fracture	0.723	0.277
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.723	0.277
K27 Peptic ulcer, site unspecified	0.722	0.278
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.722	0.278
A00-A09 Intestinal infectious diseases	0.722	0.278
M50 Cervical disk disorders	0.722	0.278
R01.1 Cardiac murmur, unspecified	0.722	0.278
T84.1 Mechanical complication of internal fixation device of bones of limb	0.722	0.278
F17 Mental and behavioural disorders due to use of tobacco	0.721	0.279
I62 Other nontraumatic intracranial haemorrhage	0.721	0.279
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.720	0.280
K22.4 Dyskinesia of oesophagus	0.720	0.280
I85 Oesophageal varices	0.717	0.282
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
I25.3 Aneurysm of heart	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
E88 Other metabolic disorders	0.717	0.283
E85 Amyloidosis	0.717	0.283
E84 Cystic fibrosis	0.717	0.283
E79 Disorders of purine and pyrimidine metabolism	0.717	0.283
E77 Disorders of glycoprotein metabolism	0.717	0.283
E76 Disorders of glycosaminoglycan metabolism	0.717	0.283
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.717	0.283
E74 Other disorders of carbohydrate metabolism	0.717	0.283
E73 Lactose intolerance	0.717	0.283
E72 Other disorders of amino-acid metabolism	0.717	0.283
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.717	0.283
E70 Disorders of aromatic amino-acid metabolism	0.717	0.283
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.717	0.283
O85-O92 Complications predominantly related to the puerperium	0.717	0.283
E78.9 Disorder of lipoprotein metabolism, unspecified	0.717	0.283
E78.8 Other disorders of lipoprotein metabolism	0.717	0.283
E78.6 Lipoprotein deficiency	0.717	0.283
E78.4 Other hyperlipidaemia	0.717	0.283
E78.3 Hyperchylomicronaemia	0.717	0.283
E78.1 Pure hyperglyceridaemia	0.717	0.283
O30 Multiple gestation	0.716	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.284
F80-F89 Disorders of psychological development	0.716	0.284
F70-F79 Mental retardation	0.716	0.284
T79-T79 Certain early complications of trauma	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
I52 Other heart disorders in diseases classified elsewhere	0.716	0.284
I48 Atrial fibrillation and flutter	0.716	0.284
I43 Cardiomyopathy in diseases classified elsewhere	0.716	0.284
I41 Myocarditis in diseases classified elsewhere	0.716	0.284
I40 Acute myocarditis	0.716	0.284
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.716	0.284
I37 Pulmonary valve disorders	0.716	0.284
I36 Nonrheumatic tricuspid valve disorders	0.716	0.284
I32 Pericarditis in diseases classified elsewhere	0.716	0.284
I30 Acute pericarditis	0.716	0.284
S61 Open wound of wrist and hand	0.714	0.286
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.714	0.286
Z50.0 Cardiac rehabilitation	0.714	0.286
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.714	0.286
M91-M94 Chondropathies	0.714	0.286
M60-M63 Disorders of muscles	0.714	0.286
M00-M03 Infectious arthropathies	0.714	0.286
I89.0 Lymphoedema, not elsewhere classified	0.713	0.287
O48 Prolonged pregnancy	0.713	0.287
K51 Ulcerative colitis	0.712	0.288
M06.9 Rheumatoid arthritis, unspecified	0.711	0.289
K22.1 Ulcer of oesophagus	0.711	0.289
Z50.2 Alcohol rehabilitation	0.710	0.290
K28 Gastrojejunal ulcer	0.710	0.290
K23 Disorders of oesophagus in diseases classified elsewhere	0.710	0.290
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.710	0.290
N03 Chronic nephritic syndrome	0.710	0.290
A80-A89 Viral infections of the central nervous system	0.709	0.291
I21.X Presumed acute myicardial infaction (unconfirmed)	0.709	0.291
I21.3 Acute transmural myocardial infarction of unspecified site	0.709	0.291
E13 Other specified diabetes mellitus	0.708	0.292
E12 Malnutrition-related diabetes mellitus	0.708	0.292
N18.5 Chronic kidney disease, stage 5	0.707	0.293
M25 Other joint disorders, not elsewhere classified	0.707	0.293
S69 Other and unspecified injuries of wrist and hand	0.707	0.293
K22.5 Diverticulum of oesophagus, acquired	0.706	0.294
K22.3 Perforation of oesophagus	0.706	0.294
K22.0 Achalasia of cardia	0.706	0.294
K01 Embedded and impacted teeth	0.706	0.294
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.706	0.294
I21.0 Acute transmural myocardial infarction of anterior wall	0.706	0.294
M15-M19 Arthrosis	0.706	0.294
I60 Subarachnoid haemorrhage	0.705	0.295
Z43 Attention to artificial openings	0.705	0.295
O74 Complications of anaesthesia during labour and delivery	0.704	0.295
O73 Retained placenta and membranes, without haemorrhage	0.704	0.295
O71 Other obstetric trauma	0.704	0.295
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.704	0.295
O65 Obstructed labour due to maternal pelvic abnormality	0.704	0.295
O61 Failed induction of labour	0.704	0.295
O60 Preterm delivery	0.704	0.295
I61 Intracerebral haemorrhage	0.704	0.296
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.704	0.296
I99 Other and unspecified disorders of circulatory system	0.704	0.296
N22 Calculus of urinary tract in diseases classified elsewhere	0.704	0.296
T15-T19 Effects of foreign body entering through natural orifice	0.703	0.296
Z03.5 Observation for other suspected cardiovascular diseases	0.703	0.297
I22.1 Subsequent myocardial infarction of inferior wall	0.703	0.297
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.703	0.297
Z95.0 Presence of cardiac pacemaker	0.703	0.297
Z39.0 Care and examination immediately after delivery	0.702	0.298
F41 Other anxiety disorders	0.702	0.298
K21 Gastro-oesophageal reflux disease	0.701	0.299
I44.7 Left bundle-branch block, unspecified	0.700	0.300
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.700	0.300
N15 Other renal tubulo-interstitial diseases	0.700	0.300
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.700	0.300
N11 Chronic tubulo-interstitial nephritis	0.700	0.300
N10 Acute tubulo-interstitial nephritis	0.700	0.300
G35-G37 Demyelinating diseases of the central nervous system	0.700	0.300
T46 Poisoning by agents primarily affecting the cardiovascular system	0.700	0.300
I31 Other diseases of pericardium	0.700	0.300
I49.0 Ventricular fibrillation and flutter	0.700	0.300
E80 Disorders of porphyrin and bilirubin metabolism	0.700	0.300
I78 Diseases of capillaries	0.699	0.301
Z94 Transplanted organ and tissue status	0.699	0.301
F38 Other mood [affective] disorders	0.698	0.302
F34 Persistent mood [affective] disorders	0.698	0.302
F30 Manic episode	0.698	0.302
F39 Unspecified mood [affective] disorder	0.698	0.302
I69 Sequelae of cerebrovascular disease	0.698	0.302
N20.9 Urinary calculus, unspecified	0.698	0.302
A41.5 Septicaemia due to other Gram-negative organisms	0.698	0.302
E83.9 Disorder of mineral metabolism, unspecified	0.698	0.302
E83.8 Other disorders of mineral metabolism	0.698	0.302
E83.3 Disorders of phosphorus metabolism	0.698	0.302
E83.2 Disorders of zinc metabolism	0.698	0.302
E83.0 Disorders of copper metabolism	0.698	0.302
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.697	0.303
Z22 Carrier of infectious disease	0.697	0.303
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.697	0.303
G80-G83 Cerebral palsy and other paralytic syndromes	0.697	0.303
Z36.0 Antenatal screening for chromosomal anomalies	0.696	0.304
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.696	0.304
Z49 Care involving dialysis	0.695	0.305
Z44 Fitting and adjustment of external prosthetic device	0.695	0.305
E29 Testicular dysfunction	0.694	0.306
A49 Bacterial infection of unspecified site	0.694	0.306
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.694	0.306
I95.8 Other hypotension	0.694	0.306
I95.0 Idiopathic hypotension	0.694	0.306
K31.6 Fistula of stomach and duodenum	0.693	0.306
K31.4 Gastric diverticulum	0.693	0.306
K31.3 Pylorospasm, not elsewhere classified	0.693	0.306
K31.2 Hourglass stricture and stenosis of stomach	0.693	0.306
K31.1 Adult hypertrophic pyloric stenosis	0.693	0.306
K31.0 Acute dilatation of stomach	0.693	0.306
I49.2 Junctional premature depolarisation	0.693	0.307
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.693	0.307
N17.9 Acute renal failure, unspecified	0.693	0.307
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.693	0.307
O72.2 Delayed and secondary postpartum haemorrhage	0.692	0.308
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.692	0.308
M34 Systemic sclerosis	0.692	0.308
M33 Dermatopolymyositis	0.692	0.308
M32 Systemic lupus erythematosus	0.692	0.308
M30 Polyarteritis nodosa and related conditions	0.692	0.308
Z10 Routine general health check-up of defined subpopulation	0.692	0.308
I49.4 Other and unspecified premature depolarisation	0.692	0.308
N18.8 Other chronic renal failure	0.691	0.309
N18.1 Chronic kidney disease, stage 1	0.691	0.309
N18.0 End-stage renal disease	0.691	0.309
F05 Delirium, not induced by alcohol and other psychoactive substances	0.691	0.309
R26 Abnormalities of gait and mobility	0.689	0.311
Z04 Examination and observation for other reasons	0.689	0.311
I49.8 Other specified cardiac arrhythmias	0.689	0.311
G30-G32 Other degenerative diseases of the nervous system	0.689	0.311
E11.8 With unspecified complications	0.688	0.312
E11.7 With multiple complications	0.688	0.312
E11.6 With other specified complications	0.688	0.312
E11.1 With ketoacidosis	0.688	0.312
E11.0 With coma	0.688	0.312
Z46 Fitting and adjustment of other devices	0.687	0.313
K11.2 Sialoadenitis	0.686	0.314
M31 Other necrotising vasculopathies	0.686	0.314
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.686	0.314
I73.0 Raynaud's syndrome	0.686	0.314
N18.2 Chronic kidney disease, stage 2	0.686	0.314
Chapter VIII Diseases of the ear and mastoid process	0.685	0.315
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.685	0.315
Z50.6 Orthoptic training	0.685	0.315
Z50.4 Psychotherapy, not elsewhere classified	0.685	0.315
Z50.3 Drug rehabilitation	0.685	0.315
O80-O84 Delivery	0.684	0.316
M81 Osteoporosis without pathological fracture	0.683	0.317
K35-K38 Diseases of appendix	0.683	0.317
A41.1 Septicaemia due to other specified staphylococcus	0.683	0.317
S42 Fracture of shoulder and upper arm	0.682	0.318
F43 Reaction to severe stress, and adjustment disorders	0.682	0.318
N13.8 Other obstructive and reflux uropathy	0.681	0.318
N13.7 Vesicoureteral-reflux-associated uropathy	0.681	0.318
N13.6 Pyonephrosis	0.681	0.318
M85 Other disorders of bone density and structure	0.681	0.319
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.681	0.319
O14.9 Preeclampsia, unspecified	0.681	0.319
Z65 Problems related to other psychosocial circumstances	0.680	0.320
Z64 Problems related to certain psychosocial circumstances	0.680	0.320
Z63 Other problems related to primary support group, including family circumstances	0.680	0.320
Z62 Other problems related to upbringing	0.680	0.320
Z61 Problems related to negative life events in childhood	0.680	0.320
Z59 Problems related to housing and economic circumstances	0.680	0.320
Z58 Problems related to physical environment	0.680	0.320
Z56 Problems related to employment and unemployment	0.680	0.320
Z55 Problems related to education and literacy	0.680	0.320
Z36.9 Antenatal screening, unspecified	0.679	0.321

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations