TreeWAS – Variant ID: rs35988099

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000
Chapter X Diseases of the respiratory system	0.997	0.003
C64-C68 Malignant neoplasms of urinary tract	0.997	0.003
Chapter XIV Diseases of the genitourinary system	0.996	0.004
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.989	0.011
M05-M14 Inflammatory polyarthropathies	0.988	0.012
N40-N51 Diseases of male genital organs	0.987	0.013
D70-D77 Other diseases of blood and blood-forming organs	0.984	0.016
J95-J99 Other diseases of the respiratory system	0.983	0.017
C64 Malignant neoplasm of kidney, except renal pelvis	0.982	0.018
Chapter VI Diseases of the nervous system	0.980	0.020
G40-G47 Episodic and paroxysmal disorders	0.976	0.024
N10-N16 Renal tubulo-interstitial diseases	0.963	0.037
D37-D48 Neoplasms of uncertain or unknown behaviour	0.962	0.038
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.961	0.039
J98 Other respiratory disorders	0.961	0.039
D80-D89 Certain disorders involving the immune mechanism	0.961	0.039
N42 Other disorders of prostate	0.959	0.041
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.954	0.046
M06 Other rheumatoid arthritis	0.953	0.047
M07 Psoriatic and enteropathic arthropathies	0.950	0.050
D50-D53 Nutritional anaemias	0.950	0.050
C67 Malignant neoplasm of bladder	0.947	0.053
N13 Obstructive and reflux uropathy	0.943	0.057
G40 Epilepsy	0.941	0.059
C43-C44 Melanoma and other malignant neoplasms of skin	0.938	0.062
C67.9 Bladder, unspecified	0.931	0.069
N20-N23 Urolithiasis	0.929	0.071
J98.1 Pulmonary collapse	0.929	0.071
M07.3 Other psoriatic arthropathies	0.923	0.077
C43 Malignant melanoma of skin	0.922	0.078
N45 Orchitis and epididymitis	0.922	0.078
N42.8 Other specified disorders of prostate	0.920	0.080
M06.9 Rheumatoid arthritis, unspecified	0.920	0.080
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.918	0.082
D00-D09 In situ neoplasms	0.912	0.088
D73 Diseases of spleen	0.911	0.089
D50 Iron deficiency anaemia	0.908	0.092
N41 Inflammatory diseases of prostate	0.907	0.093
D50.8 Other iron deficiency anaemias	0.905	0.095
G43 Migraine	0.904	0.096
C43.6 Malignant melanoma of upper limb, including shoulder	0.903	0.097
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.899	0.101
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.897	0.103
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.896	0.104
Chapter XII Diseases of the skin and subcutaneous tissue	0.892	0.108
N60-N64 Disorders of breast	0.890	0.110
M86-M90 Other osteopathies	0.888	0.112
Q60-Q64 Congenital malformations of the urinary system	0.886	0.114
J09-J18 Influenza and pneumonia	0.886	0.114
Chapter XX External causes of morbidity and mortality	0.883	0.117
N60 Benign mammary dysplasia	0.879	0.121
C83 Diffuse non-Hodgkin's lymphoma	0.879	0.121
J30-J39 Other diseases of upper respiratory tract	0.877	0.123
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.875	0.125
N20 Calculus of kidney and ureter	0.871	0.129
J33 Nasal polyp	0.871	0.129
C51-C58 Malignant neoplasms of female genital organs	0.869	0.131
D86 Sarcoidosis	0.868	0.132
M10 Gout	0.868	0.132
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.865	0.135
L40-L45 Papulosquamous disorders	0.859	0.141
G43.9 Migraine, unspecified	0.859	0.141
M05 Seropositive rheumatoid arthritis	0.858	0.142
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.858	0.142
J33.8 Other polyp of sinus	0.856	0.144
M07.39 Other psoriatic arthropathies (Site unspecified)	0.852	0.148
G62 Other polyneuropathies	0.849	0.151
C43.5 Malignant melanoma of trunk	0.845	0.155
D72 Other disorders of white blood cells	0.844	0.156
G47 Sleep disorders	0.843	0.157
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.842	0.158
L40 Psoriasis	0.841	0.159
J95 Postprocedural respiratory disorders, not elsewhere classified	0.840	0.160
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.839	0.161
D75 Other diseases of blood and blood-forming organs	0.838	0.162
L80-L99 Other disorders of the skin and subcutaneous tissue	0.837	0.163
N41.1 Chronic prostatitis	0.837	0.163
G44 Other headache syndromes	0.835	0.164
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.834	0.166
Q80-Q89 Other congenital malformations	0.832	0.168
C91 Lymphoid leukaemia	0.829	0.171
M60-M63 Disorders of muscles	0.826	0.173
D68 Other coagulation defects	0.826	0.174
D70 Agranulocytosis	0.826	0.174
Chapter V Mental and behavioural disorders	0.824	0.176
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.824	0.176
N60.1 Diffuse cystic mastopathy	0.823	0.177
C83.3 Large cell (diffuse)	0.820	0.180
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.820	0.180
M07.30 Other psoriatic arthropathies (Multiple sites)	0.819	0.181
M89 Other disorders of bone	0.818	0.182
J90-J94 Other diseases of pleura	0.817	0.183
N20.1 Calculus of ureter	0.815	0.185
N42.1 Congestion and haemorrhage of prostate	0.814	0.186
N99-N99 Other disorders of the genitourinary system	0.814	0.186
N13.5 Kinking and stricture of ureter without hydronephrosis	0.813	0.187
D07 Carcinoma in situ of other and unspecified genital organs	0.813	0.187
X60-X84 Intentional self-harm	0.813	0.187
Q61 Cystic kidney disease	0.812	0.188
N60.0 Solitary cyst of breast	0.812	0.188
J15 Bacterial pneumonia, not elsewhere classified	0.810	0.190
N41.0 Acute prostatitis	0.809	0.191
D84 Other immunodeficiencies	0.809	0.191
L40.5 Arthropathic psoriasis	0.809	0.191
J60-J70 Lung diseases due to external agents	0.807	0.193
L90 Atrophic disorders of skin	0.806	0.194
D03 Melanoma in situ	0.804	0.196
D55-D59 Haemolytic anaemias	0.802	0.198
D37.2 Small intestine	0.801	0.199
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.800	0.200
J80-J84 Other respiratory diseases principally affecting the interstitium	0.798	0.202
D73.0 Hyposplenism	0.796	0.204
D73.5 Infarction of spleen	0.795	0.205
N60.8 Other benign mammary dysplasias	0.792	0.207
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.792	0.208
N13.3 Other and unspecified hydronephrosis	0.790	0.210
D09 Carcinoma in situ of other and unspecified sites	0.790	0.210
G40.5 Special epileptic syndromes	0.786	0.214
M10.9 Gout, unspecified	0.783	0.217
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.782	0.218
N47 Redundant prepuce, phimosis and paraphimosis	0.782	0.218
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.780	0.220
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.776	0.224
M06.0 Seronegative rheumatoid arthritis	0.775	0.225
J33.0 Polyp of nasal cavity	0.768	0.232
J98.4 Other disorders of lung	0.768	0.232
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.768	0.232
R79 Other abnormal findings of blood chemistry	0.767	0.233
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.767	0.233
R79.8 Other specified abnormal findings of blood chemistry	0.766	0.234
M05.9 Seropositive rheumatoid arthritis, unspecified	0.766	0.234
C84 Peripheral and cutaneous T-cell lymphomas	0.764	0.236
M80-M85 Disorders of bone density and structure	0.763	0.237
J98.5 Diseases of mediastinum, not elsewhere classified	0.762	0.238
N46 Male infertility	0.761	0.239
D10-D36 Benign neoplasms	0.761	0.239
M91-M94 Chondropathies	0.761	0.239
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.759	0.241
G62.9 Polyneuropathy, unspecified	0.759	0.241
L90.5 Scar conditions and fibrosis of skin	0.758	0.242
C67.0 Trigone of bladder	0.757	0.243
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.756	0.244
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.754	0.246
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.751	0.249
J98.9 Respiratory disorder, unspecified	0.750	0.250
N10 Acute tubulo-interstitial nephritis	0.749	0.251
Chapter XXII Codes for special purposes	0.748	0.252
G61 Inflammatory polyneuropathy	0.747	0.253
G40.9 Epilepsy, unspecified	0.747	0.253
C49 Malignant neoplasm of other connective and soft tissue	0.746	0.254
L81 Other disorders of pigmentation	0.745	0.255
C66 Malignant neoplasm of ureter	0.745	0.255
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.743	0.257
M07.36 Other psoriatic arthropathies (Lower leg)	0.742	0.258
N15 Other renal tubulo-interstitial diseases	0.742	0.258
N42.0 Calculus of prostate	0.741	0.259
J00-J06 Acute upper respiratory infections	0.738	0.261
N23 Unspecified renal colic	0.737	0.263
G00-G09 Inflammatory diseases of the central nervous system	0.735	0.265
X62.9 Unspecified place	0.734	0.266
D86.0 Sarcoidosis of lung	0.732	0.268
J99 Respiratory disorders in diseases classified elsewhere	0.731	0.269
D37.6 Liver, gallbladder and bile ducts	0.730	0.270
L40.9 Psoriasis, unspecified	0.730	0.270
C01 Malignant neoplasm of base of tongue	0.730	0.270
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.729	0.270
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.729	0.271
J39 Other diseases of upper respiratory tract	0.729	0.271
J15.2 Pneumonia due to staphylococcus	0.729	0.271
J95.8 Other postprocedural respiratory disorders	0.729	0.271
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.728	0.272
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.728	0.272
D68.9 Coagulation defect, unspecified	0.727	0.272
N42.2 Atrophy of prostate	0.727	0.273
M20-M25 Other joint disorders	0.726	0.274
Q38-Q45 Other congenital malformations of the digestive system	0.726	0.274
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.725	0.275
D80 Immunodeficiency with predominantly antibody defects	0.725	0.275
Q20-Q28 Congenital malformations of the circulatory system	0.725	0.275
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.724	0.276
D37.1 Stomach	0.724	0.276
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.723	0.277
N13.9 Obstructive and reflux uropathy, unspecified	0.723	0.277
Y60-Y69 Misadventures to patients during surgical and medical care	0.723	0.277
J90 Pleural effusion, not elsewhere classified	0.723	0.277
J84 Other interstitial pulmonary diseases	0.722	0.278
M89.0 Algoneurodystrophy	0.720	0.280
G60 Hereditary and idiopathic neuropathy	0.720	0.280
N13.8 Other obstructive and reflux uropathy	0.720	0.280
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.719	0.281
J98.0 Diseases of bronchus, not elsewhere classified	0.718	0.281
C88 Malignant immunoproliferative diseases	0.717	0.283
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.717	0.283
D22 Melanocytic naevi	0.715	0.285
C68 Malignant neoplasm of other and unspecified urinary organs	0.715	0.285
C65 Malignant neoplasm of renal pelvis	0.715	0.285
G62.8 Other specified polyneuropathies	0.713	0.287
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.711	0.289
J98.6 Disorders of diaphragm	0.710	0.290
J14 Pneumonia due to Haemophilus influenzae	0.709	0.291
D72.1 Eosinophilia	0.708	0.291
M14 Arthropathies in other diseases classified elsewhere	0.708	0.292
M12 Other specific arthropathies	0.708	0.292
M09 Juvenile arthritis in diseases classified elsewhere	0.708	0.292
M08 Juvenile arthritis	0.708	0.292
N50 Other disorders of male genital organs	0.708	0.292
G47.1 Disorders of excessive somnolence [hypersomnias]	0.708	0.292
N51 Disorders of male genital organs in diseases classified elsewhere	0.708	0.292
N44 Torsion of testis	0.708	0.292
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.708	0.292
D52 Folate deficiency anaemia	0.706	0.294
D74 Methaemoglobinaemia	0.706	0.294
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.706	0.294
D71 Functional disorders of polymorphonuclear neutrophils	0.706	0.294
G44.2 Tension-type headache	0.705	0.295
C02 Malignant neoplasm of other and unspecified parts of tongue	0.705	0.295
J96 Respiratory failure, not elsewhere classified	0.705	0.295
D09.0 Bladder	0.702	0.298
N11 Chronic tubulo-interstitial nephritis	0.701	0.299
D86.1 Sarcoidosis of lymph nodes	0.701	0.299
C51 Malignant neoplasm of vulva	0.700	0.300
C56 Malignant neoplasm of ovary	0.700	0.300
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.700	0.300
D84.9 Immunodeficiency, unspecified	0.700	0.300
L90.0 Lichen sclerosus et atrophicus	0.700	0.300
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.700	0.300
G46 Vascular syndromes of brain in cerebrovascular diseases	0.699	0.300
R47-R49 Symptoms and signs involving speech and voice	0.699	0.301
Q61.2 Polycystic kidney, adult type	0.699	0.301
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.697	0.303
D60-D64 Aplastic and other anaemias	0.697	0.303
M40-M43 Deforming dorsopathies	0.696	0.304
D37.7 Other digestive organs	0.695	0.304
F17 Mental and behavioural disorders due to use of tobacco	0.695	0.305
M35 Other systemic involvement of connective tissue	0.695	0.305
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.694	0.306
C43.4 Malignant melanoma of scalp and neck	0.693	0.306
D51 Vitamin B12 deficiency anaemia	0.693	0.307
D86.9 Sarcoidosis, unspecified	0.692	0.308
J30 Vasomotor and allergic rhinitis	0.692	0.308
N20.9 Urinary calculus, unspecified	0.692	0.308
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.690	0.310
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.690	0.310
Q60 Renal agenesis and other reduction defects of kidney	0.690	0.310
J10 Influenza due to identified influenza virus	0.690	0.310
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.689	0.310
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.689	0.310
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.689	0.311
Q35-Q37 Cleft lip and cleft palate	0.689	0.311
Q30-Q34 Congenital malformations of the respiratory system	0.689	0.311
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.689	0.311
J98.3 Compensatory emphysema	0.689	0.311
J98.2 Interstitial emphysema	0.689	0.311
R74 Abnormal serum enzyme levels	0.689	0.311
D83 Common variable immunodeficiency	0.689	0.311
D82 Immunodeficiency associated with other major defects	0.689	0.311
D81 Combined immunodeficiencies	0.689	0.311
C67.3 Anterior wall of bladder	0.688	0.312
R04 Haemorrhage from respiratory passages	0.687	0.312
N42.3 Dysplasia of prostate	0.687	0.313
V80-V89 Other land transport accidents	0.687	0.313
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.686	0.314
N60.3 Fibrosclerosis of breast	0.685	0.315
J85 Abscess of lung and mediastinum	0.685	0.315
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.684	0.316
C95 Leukaemia of unspecified cell type	0.684	0.316
C94 Other leukaemias of specified cell type	0.684	0.316
C93 Monocytic leukaemia	0.684	0.316
C86 Other specified types of T/NK-cell lymphoma	0.684	0.316
D39.1 Ovary	0.684	0.316
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.684	0.316
N00-N08 Glomerular diseases	0.684	0.316
M06.8 Other specified rheumatoid arthritis	0.684	0.316
M06.4 Inflammatory polyarthropathy	0.684	0.316
M06.2 Rheumatoid bursitis	0.684	0.316
M06.1 Adult-onset Still's disease	0.684	0.316
Q61.3 Polycystic kidney, unspecified	0.683	0.317
G47.3 Sleep apnoea	0.683	0.317
D22.6 Melanocytic naevi of upper limb, including shoulder	0.683	0.317
R04.0 Epistaxis	0.682	0.318
M07.6 Other enteropathic arthropathies	0.681	0.319
M07.5 Arthropathy in ulcerative colitis	0.681	0.319
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.681	0.319
M07.2 Psoriatic spondylitis	0.681	0.319
M07.1 Arthritis mutilans	0.681	0.319
M07.0 Distal interphalangeal psoriatic arthropathy	0.681	0.319
D53 Other nutritional anaemias	0.681	0.319
M89.8 Other specified disorders of bone	0.681	0.319
D37.4 Colon	0.680	0.320
D47.1 Chronic myeloproliferative disease	0.680	0.320
D75.8 Other specified diseases of blood and blood-forming organs	0.680	0.320
Q83 Congenital malformations of breast	0.679	0.321
C67.8 Overlapping lesion of bladder	0.679	0.321
C67.7 Urachus	0.679	0.321
C54 Malignant neoplasm of corpus uteri	0.677	0.323
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.677	0.323
N13.7 Vesicoureteral-reflux-associated uropathy	0.676	0.324
N13.6 Pyonephrosis	0.676	0.324
D17 Benign lipomatous neoplasm	0.676	0.324
J94 Other pleural conditions	0.676	0.324
M35.3 Polymyalgia rheumatica	0.676	0.324
D03.7 Melanoma in situ of lower limb, including hip	0.676	0.324
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.676	0.324
D68.8 Other specified coagulation defects	0.675	0.324
C91.9 Lymphoid leukaemia, unspecified	0.675	0.325
G40.8 Other epilepsy	0.674	0.326
G40.7 Petit mal, unspecified, without grand mal seizures	0.674	0.326
G40.4 Other generalised epilepsy and epileptic syndromes	0.674	0.326
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.674	0.326
C91.1 Chronic lymphocytic leukaemia	0.674	0.326
G12 Spinal muscular atrophy and related syndromes	0.674	0.326
C81 Hodgkin's disease	0.674	0.326
N20.2 Calculus of kidney with calculus of ureter	0.673	0.327
D75.2 Essential thrombocytosis	0.673	0.327
J15.1 Pneumonia due to Pseudomonas	0.672	0.328
V40-V49 Car occupant injured in transport accident	0.672	0.328
D89.2 Hypergammaglobulinaemia, unspecified	0.671	0.329
J17 Pneumonia in diseases classified elsewhere	0.670	0.329
G41 Status epilepticus	0.670	0.330
J33.9 Nasal polyp, unspecified	0.670	0.330
M13 Other arthritis	0.669	0.330
D07.5 Prostate	0.669	0.331
L83 Acanthosis nigricans	0.669	0.331
D72.8 Other specified disorders of white blood cells	0.668	0.332
M00-M03 Infectious arthropathies	0.667	0.333
D07.1 Vulva	0.667	0.333
J69 Pneumonitis due to solids and liquids	0.667	0.333
M87 Osteonecrosis	0.667	0.333
N22 Calculus of urinary tract in diseases classified elsewhere	0.666	0.334
M60 Myositis	0.666	0.334
Q50-Q56 Congenital malformations of genital organs	0.666	0.334
M10.97 Gout, unspecified (Ankle and foot)	0.665	0.335
J86 Pyothorax	0.664	0.336
G47.9 Sleep disorder, unspecified	0.663	0.337
W50-W64 Exposure to animate mechanical forces	0.663	0.337
M07.38 Other psoriatic arthropathies (Other)	0.661	0.338
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.661	0.338
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.661	0.338
M07.34 Other psoriatic arthropathies (Hand)	0.661	0.338
M07.33 Other psoriatic arthropathies (Forearm)	0.661	0.338
M07.32 Other psoriatic arthropathies (Upper arm)	0.661	0.338
M07.31 Other psoriatic arthropathies (Shoulder region)	0.661	0.338
C43.8 Overlapping malignant melanoma of skin	0.661	0.339
C43.2 Malignant melanoma of ear and external auricular canal	0.661	0.339
C43.1 Malignant melanoma of eyelid, including canthus	0.661	0.339
C43.0 Malignant melanoma of lip	0.661	0.339
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.661	0.339
X50-X57 Overexertion, travel and privation	0.661	0.339
D47.4 Osteomyelofibrosis	0.661	0.339
D69 Purpura and other haemorrhagic conditions	0.661	0.339
G44.0 Cluster headache syndrome	0.660	0.340
M06.98 Rheumatoid arthritis, unspecified (Other)	0.659	0.341
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.659	0.341
M06.3 Rheumatoid nodule	0.658	0.342
G64 Other disorders of peripheral nervous system	0.658	0.342
F17.1 Harmful use	0.657	0.343
R47 Speech disturbances, not elsewhere classified	0.656	0.344
M62 Other disorders of muscle	0.656	0.344
D03.5 Melanoma in situ of trunk	0.656	0.344
M10.99 Gout, unspecified (Site unspecified)	0.655	0.345
M80 Osteoporosis with pathological fracture	0.654	0.346
C10 Malignant neoplasm of oropharynx	0.654	0.346
D02 Carcinoma in situ of middle ear and respiratory system	0.654	0.346
D01 Carcinoma in situ of other and unspecified digestive organs	0.654	0.346
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.654	0.346
N50.9 Disorder of male genital organs, unspecified	0.654	0.346
C49.3 Connective and soft tissue of thorax	0.654	0.346
D73.9 Disease of spleen, unspecified	0.653	0.347
D73.8 Other diseases of spleen	0.653	0.347
D73.4 Cyst of spleen	0.653	0.347
D73.3 Abscess of spleen	0.653	0.347
D73.2 Chronic congestive splenomegaly	0.653	0.347
D73.1 Hypersplenism	0.653	0.347
C43.9 Malignant melanoma of skin, unspecified	0.653	0.347
R73 Elevated blood glucose level	0.652	0.348
G11 Hereditary ataxia	0.651	0.349
C83.1 Small cleaved cell (diffuse)	0.651	0.349
Q63 Other congenital malformations of kidney	0.651	0.349
D50.1 Sideropenic dysphagia	0.651	0.349
N41.8 Other inflammatory diseases of prostate	0.650	0.349
N41.3 Prostatocystitis	0.650	0.349
N41.2 Abscess of prostate	0.650	0.349
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.651	0.349
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.650	0.350
C55 Malignant neoplasm of uterus, part unspecified	0.648	0.352
G43.8 Other migraine	0.648	0.352
G43.3 Complicated migraine	0.648	0.352
G43.2 Status migrainosus	0.648	0.352
G43.0 Migraine without aura [common migraine]	0.648	0.352
D45 Polycythaemia vera	0.648	0.352
C67.6 Ureteric orifice	0.647	0.353
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.646	0.353
G70-G73 Diseases of myoneural junction and muscle	0.646	0.354
X10-X19 Contact with heat and hot substances	0.646	0.354
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.645	0.355
J92 Pleural plaque	0.645	0.355
D67 Hereditary factor IX deficiency	0.644	0.355
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.644	0.355
Y00-Y09 Assault	0.644	0.356
C83.0 Small cell (diffuse)	0.643	0.356
J02 Acute pharyngitis	0.643	0.357
L81.4 Other melanin hyperpigmentation	0.642	0.358
C90 Multiple myeloma and malignant plasma cell neoplasms	0.642	0.358
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.642	0.358
D37.9 Digestive organ, unspecified	0.642	0.358
D37.3 Appendix	0.642	0.358
Q00-Q07 Congenital malformations of the nervous system	0.641	0.359
L94 Other localised connective tissue disorders	0.640	0.359
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.640	0.359
G30-G32 Other degenerative diseases of the nervous system	0.640	0.360
R03 Abnormal blood-pressure reading, without diagnosis	0.640	0.360
L10-L14 Bullous disorders	0.639	0.361
J84.1 Other interstitial pulmonary diseases with fibrosis	0.639	0.361
X58-X59 Accidental exposure to other and unspecified factors	0.638	0.362
X40-X49 Accidental poisoning by and exposure to noxious substances	0.638	0.362
D68.5 Primary Thrombophilia	0.637	0.363
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.636	0.363
L40.0 Psoriasis vulgaris	0.636	0.364
M11 Other crystal arthropathies	0.636	0.364
M86 Osteomyelitis	0.636	0.364
D47.2 Monoclonal gammopathy	0.636	0.364
L80 Vitiligo	0.636	0.364
D07.4 Penis	0.636	0.364
Q64 Other congenital malformations of urinary system	0.635	0.365
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.635	0.365
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.635	0.365
J37 Chronic laryngitis and laryngotracheitis	0.635	0.365
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.635	0.365
J12 Viral pneumonia, not elsewhere classified	0.635	0.365
J09 Influenza due to certain identified influenza virus	0.635	0.365
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.634	0.366
Y35-Y36 Legal intervention and operations of war	0.633	0.367
Y10-Y34 Event of undetermined intent	0.633	0.367
X85-X99 Assault	0.633	0.367
X30-X39 Exposure to forces of nature	0.633	0.367
X00-X09 Exposure to smoke, fire and flames	0.633	0.367
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.633	0.367
W75-W84 Other accidental threats to breathing	0.633	0.367
W65-W74 Accidental drowning and submersion	0.633	0.367
V98-V99 Other and unspecified transport accidents	0.633	0.367
V95-V97 Air and space transport accidents	0.633	0.367
V90-V94 Water transport accidents	0.633	0.367
V70-V79 Bus occupant injured in transport accident	0.633	0.367
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.633	0.367
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.633	0.367
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.633	0.367
V01-V09 Pedestrian injured in transport accident	0.633	0.367
Q85 Phakomatoses, not elsewhere classified	0.632	0.368
R02 Gangrene, not elsewhere classified	0.632	0.368
N21 Calculus of lower urinary tract	0.632	0.368
D58 Other hereditary haemolytic anaemias	0.631	0.369
V20-V29 Motorcycle rider injured in transport accident	0.631	0.369
F99-F99 Unspecified mental disorder	0.631	0.369
N60.9 Benign mammary dysplasia, unspecified	0.631	0.369
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.630	0.370
C83.7 Burkitt's tumour	0.630	0.370
C83.6 Undifferentiated (diffuse)	0.630	0.370
C83.5 Lymphoblastic (diffuse)	0.630	0.370
C83.4 Immunoblastic (diffuse)	0.630	0.370
C83.2 Mixed small and large cell (diffuse)	0.630	0.370
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.629	0.371
J15.0 Pneumonia due to Klebsiella pneumoniae	0.629	0.371
D66 Hereditary factor VIII deficiency	0.628	0.371
J11 Influenza, virus not identified	0.627	0.372
W00-W19 Falls	0.626	0.374
M24 Other specific joint derangements	0.626	0.374
L93 Lupus erythematosus	0.625	0.374
D16 Benign neoplasm of bone and articular cartilage	0.625	0.375
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.625	0.375
R77 Other abnormalities of plasma proteins	0.625	0.375
M90 Osteopathies in diseases classified elsewhere	0.624	0.375
J33.1 Polypoid sinus degeneration	0.624	0.376
R74.8 Abnormal levels of other serum enzymes	0.624	0.376
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.624	0.376
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.623	0.377
D03.4 Melanoma in situ of scalp and neck	0.623	0.377
C67.1 Dome of bladder	0.623	0.377
C57 Malignant neoplasm of other and unspecified female genital organs	0.623	0.377
C58 Malignant neoplasm of placenta	0.623	0.377
C52 Malignant neoplasm of vagina	0.623	0.377
G61.0 Guillain-Barre syndrome	0.623	0.377
J95.0 Tracheostomy malfunction	0.623	0.377
D86.8 Sarcoidosis of other and combined sites	0.622	0.377
D86.3 Sarcoidosis of skin	0.622	0.377
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.622	0.377
M10.4 Other secondary gout	0.622	0.377
M10.3 Gout due to impairment of renal function	0.622	0.377
M10.2 Drug-induced gout	0.622	0.377
M10.1 Lead-induced gout	0.622	0.377
M10.0 Idiopathic gout	0.622	0.377
G45 Transient cerebral ischaemic attacks and related syndromes	0.622	0.378
Y57 Other and unspecified drugs and medicaments	0.622	0.378
R47.8 Other and unspecified speech disturbances	0.621	0.379
Q61.0 Congenital single renal cyst	0.621	0.379

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations