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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs36225840
log Bayes Factor = 7.99473
Chromosome 4   position 146,076,413  (GRCh37) Explore rs36225840 on Ensembl!
Variant rs36225840 is part of Cluster X0283

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
A30-A49 Other bacterial diseases
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
S80-S89 Injuries to the knee and lower leg
0.997 0.003 0.000
S82 Fracture of lower leg, including ankle
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.985 0.015 0.000
A41 Other septicaemia
0.982 0.018 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.982 0.018 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.982 0.018 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.980 0.020 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.980 0.020 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.977 0.023 0.000
Chapter VI Diseases of the nervous system
0.976 0.024 0.000
Chapter II Neoplasms
0.971 0.029 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.971 0.029 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.967 0.033 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.965 0.035 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.963 0.037 0.000
S82.6 Fracture of lateral malleolus
0.957 0.043 0.000
A40 Streptococcal septicaemia
0.955 0.045 0.000
A41.9 Septicaemia, unspecified
0.950 0.050 0.000
T81 Complications of procedures, not elsewhere classified
0.948 0.052 0.000
T51 Toxic effect of alcohol
0.947 0.053 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.945 0.055 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.942 0.058 0.000
F10.2 Dependence syndrome
0.942 0.058 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.941 0.059 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.933 0.067 0.000
D70 Agranulocytosis
0.932 0.068 0.000
S82.60 Fracture of lateral malleolus (closed)
0.930 0.070 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.929 0.071 0.000
A00-A09 Intestinal infectious diseases
0.929 0.071 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.928 0.072 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.926 0.074 0.000
S81 Open wound of lower leg
0.922 0.078 0.000
L03 Cellulitis
0.921 0.079 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.920 0.080 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.915 0.085 0.000
C79 Secondary malignant neoplasm of other sites
0.914 0.086 0.000
F05.9 Delirium, unspecified
0.913 0.087 0.000
A49 Bacterial infection of unspecified site
0.908 0.092 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.908 0.092 0.000
D60-D64 Aplastic and other anaemias
0.900 0.100 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.900 0.100 0.000
G90-G99 Other disorders of the nervous system
0.899 0.101 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.898 0.102 0.000
T51.0 Ethanol
0.889 0.111 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.889 0.111 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.887 0.113 0.000
S81.8 Open wound of other parts of lower leg
0.883 0.117 0.000
F10.1 Harmful use
0.882 0.118 0.000
S82.3 Fracture of lower end of tibia
0.882 0.118 0.000
S82.1 Fracture of upper end of tibia
0.881 0.119 0.000
S50-S59 Injuries to the elbow and forearm
0.878 0.122 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.877 0.123 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.876 0.124 0.000
F03 Unspecified dementia
0.874 0.126 0.000
M05-M14 Inflammatory polyarthropathies
0.872 0.128 0.000
D75 Other diseases of blood and blood-forming organs
0.872 0.128 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.866 0.134 0.000
D48.1 Connective and other soft tissue
0.860 0.140 0.000
Chapter XXII Codes for special purposes
0.855 0.145 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.852 0.148 0.000
M10 Gout
0.850 0.150 0.000
F10.3 Withdrawal state
0.849 0.151 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.847 0.153 0.000
C79.6 Secondary malignant neoplasm of ovary
0.847 0.153 0.000
L40-L45 Papulosquamous disorders
0.847 0.153 0.000
Chapter XX External causes of morbidity and mortality
0.846 0.154 0.000
M20-M25 Other joint disorders
0.846 0.154 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.841 0.159 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.839 0.161 0.000
L03.1 Cellulitis of other parts of limb
0.837 0.163 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.836 0.164 0.000
M10.9 Gout, unspecified
0.834 0.166 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.831 0.169 0.000
S82.2 Fracture of shaft of tibia
0.830 0.170 0.000
T51.9 Alcohol, unspecified
0.830 0.170 0.000
F30-F39 Mood [affective] disorders
0.829 0.171 0.000
C77.9 Lymph node, unspecified
0.825 0.175 0.000
D61 Other aplastic anaemias
0.822 0.177 0.000
M10.99 Gout, unspecified (Site unspecified)
0.818 0.182 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.816 0.184 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.816 0.184 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.813 0.187 0.000
A40.9 Streptococcal septicaemia, unspecified
0.812 0.188 0.000
T58 Toxic effect of carbon monoxide
0.811 0.189 0.000
G62 Other polyneuropathies
0.811 0.189 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.811 0.189 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.808 0.192 0.000
L05 Pilonidal cyst
0.807 0.193 0.000
L03.3 Cellulitis of trunk
0.807 0.193 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.807 0.193 0.000
S32 Fracture of lumbar spine and pelvis
0.806 0.194 0.000
A40.8 Other streptococcal septicaemia
0.802 0.198 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.802 0.198 0.000
S82.10 Fracture of upper end of tibia (closed)
0.799 0.201 0.000
G61 Inflammatory polyneuropathy
0.798 0.202 0.000
D00-D09 In situ neoplasms
0.798 0.202 0.000
L03.8 Cellulitis of other sites
0.798 0.202 0.000
A40.0 Septicaemia due to streptococcus, group A
0.798 0.202 0.000
A49.8 Other bacterial infections of unspecified site
0.798 0.202 0.000
S82.30 Fracture of lower end of tibia (closed)
0.797 0.203 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.793 0.207 0.000
G91 Hydrocephalus
0.792 0.208 0.000
S90-S99 Injuries to the ankle and foot
0.790 0.210 0.000
M86-M90 Other osteopathies
0.788 0.212 0.000
G40-G47 Episodic and paroxysmal disorders
0.788 0.212 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.788 0.212 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.788 0.212 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.785 0.215 0.000
F00 Dementia in Alzheimer's disease
0.781 0.219 0.000
M25 Other joint disorders, not elsewhere classified
0.780 0.220 0.000
B25-B34 Other viral diseases
0.779 0.221 0.000
G95 Other diseases of spinal cord
0.778 0.222 0.000
A39 Meningococcal infection
0.777 0.223 0.000
L08 Other local infections of skin and subcutaneous tissue
0.777 0.223 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.776 0.223 0.000
A40.1 Septicaemia due to streptococcus, group B
0.775 0.225 0.000
T39.0 Salicylates
0.775 0.225 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.774 0.225 0.000
S82.8 Fractures of other parts of lower leg
0.774 0.226 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.773 0.227 0.000
L04 Acute lymphadenitis
0.772 0.228 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.769 0.231 0.000
A04 Other bacterial intestinal infections
0.768 0.232 0.000
D61.9 Aplastic anaemia, unspecified
0.767 0.233 0.000
A49.1 Streptococcal infection, unspecified
0.763 0.237 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.762 0.238 0.000
T56 Toxic effect of metals
0.760 0.240 0.000
M21 Other acquired deformities of limbs
0.759 0.241 0.000
G70-G73 Diseases of myoneural junction and muscle
0.759 0.241 0.000
S50 Superficial injury of forearm
0.759 0.241 0.000
X60-X84 Intentional self-harm
0.759 0.241 0.000
D75.1 Secondary polycythaemia
0.758 0.242 0.000
B65-B83 Helminthiases
0.757 0.243 0.000
F60-F69 Disorders of adult personality and behaviour
0.757 0.243 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.756 0.244 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.756 0.244 0.000
T59 Toxic effect of other gases, fumes and vapours
0.754 0.246 0.000
S20-S29 Injuries to the thorax
0.754 0.246 0.000
D64 Other anaemias
0.753 0.247 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.753 0.247 0.000
S82.5 Fracture of medial malleolus
0.752 0.248 0.000
T00-T07 Injuries involving multiple body regions
0.751 0.249 0.000
D55-D59 Haemolytic anaemias
0.751 0.249 0.000
C79.2 Secondary malignant neoplasm of skin
0.749 0.251 0.000
C77.0 Lymph nodes of head, face and neck
0.749 0.251 0.000
C88 Malignant immunoproliferative diseases
0.749 0.251 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.748 0.252 0.000
B50-B64 Protozoal diseases
0.747 0.253 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.747 0.253 0.000
L03.9 Cellulitis, unspecified
0.746 0.253 0.000
F10.0 Acute intoxication
0.746 0.254 0.000
D45 Polycythaemia vera
0.745 0.255 0.000
G30-G32 Other degenerative diseases of the nervous system
0.743 0.257 0.000
S82.20 Fracture of shaft of tibia (closed)
0.741 0.259 0.000
F02 Dementia in other diseases classified elsewhere
0.740 0.260 0.000
S37 Injury of urinary and pelvic organs
0.740 0.260 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.740 0.260 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.740 0.260 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.739 0.261 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.738 0.262 0.000
M65-M68 Disorders of synovium and tendon
0.738 0.262 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.738 0.262 0.000
M31 Other necrotising vasculopathies
0.736 0.264 0.000
B15-B19 Viral hepatitis
0.735 0.264 0.000
S70-S79 Injuries to the hip and thigh
0.735 0.265 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.734 0.266 0.000
S82.0 Fracture of patella
0.734 0.266 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.734 0.266 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.734 0.266 0.000
A41.8 Other specified septicaemia
0.734 0.266 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.734 0.266 0.000
T63 Toxic effect of contact with venomous animals
0.733 0.267 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.729 0.271 0.000
M91-M94 Chondropathies
0.729 0.271 0.000
S10-S19 Injuries to the neck
0.728 0.271 0.000
G40 Epilepsy
0.728 0.272 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.726 0.274 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.725 0.274 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.725 0.275 0.000
B35-B49 Mycoses
0.724 0.276 0.000
A46 Erysipelas
0.724 0.276 0.000
L40 Psoriasis
0.724 0.276 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.722 0.278 0.000
S56 Injury of muscle and tendon at forearm level
0.722 0.278 0.000
G60 Hereditary and idiopathic neuropathy
0.722 0.278 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.721 0.279 0.000
M25.5 Pain in joint
0.721 0.279 0.000
Q00-Q07 Congenital malformations of the nervous system
0.720 0.280 0.000
C81 Hodgkin's disease
0.719 0.280 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.719 0.281 0.000
F22 Persistent delusional disorders
0.718 0.282 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.718 0.282 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.718 0.282 0.000
M89 Other disorders of bone
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D48.6 Breast
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A65-A69 Other spirochaetal diseases
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
S36 Injury of intra-abdominal organs
0.717 0.283 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.716 0.284 0.000
A48 Other bacterial diseases, not elsewhere classified
0.716 0.284 0.000
A44 Bartonellosis
0.716 0.284 0.000
A43 Nocardiosis
0.716 0.284 0.000
A42 Actinomycosis
0.716 0.284 0.000
A37 Whooping cough
0.716 0.284 0.000
A36 Diphtheria
0.716 0.284 0.000
A32 Listeriosis
0.716 0.284 0.000
A31 Infection due to other mycobacteria
0.716 0.284 0.000
A30 Leprosy [Hansen's disease]
0.716 0.284 0.000
A38 Scarlet fever
0.716 0.284 0.000
A35 Other tetanus
0.716 0.284 0.000
A34 Obstetrical tetanus
0.716 0.284 0.000
A33 Tetanus neonatorum
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
S88 Traumatic amputation of lower leg
0.715 0.285 0.000
S87 Crushing injury of lower leg
0.715 0.285 0.000
S86 Injury of muscle and tendon at lower leg level
0.715 0.285 0.000
S85 Injury of blood vessels at lower leg level
0.715 0.285 0.000
S84 Injury of nerves at lower leg level
0.715 0.285 0.000
A49.0 Staphylococcal infection, unspecified
0.713 0.287 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.713 0.287 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.713 0.287 0.000
S82.9 Fracture of lower leg, part unspecified
0.712 0.287 0.000
S82.7 Multiple fractures of lower leg
0.712 0.287 0.000
G61.0 Guillain-Barre syndrome
0.711 0.289 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.711 0.289 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.711 0.289 0.000
M35 Other systemic involvement of connective tissue
0.710 0.290 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.709 0.291 0.000
W20-W49 Exposure to inanimate mechanical forces
0.709 0.291 0.000
C77.4 Inguinal and lower limb lymph nodes
0.709 0.291 0.000
T92 Sequelae of injuries of upper limb
0.707 0.293 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.706 0.294 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.706 0.294 0.000
A41.4 Septicaemia due to anaerobes
0.704 0.296 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.704 0.296 0.000
T65 Toxic effect of other and unspecified substances
0.704 0.296 0.000
T62 Toxic effect of other noxious substances eaten as food
0.704 0.296 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.704 0.296 0.000
T60 Toxic effect of pesticides
0.704 0.296 0.000
T57 Toxic effect of other inorganic substances
0.704 0.296 0.000
T54 Toxic effect of corrosive substances
0.704 0.296 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.704 0.296 0.000
T52 Toxic effect of organic solvents
0.704 0.296 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.704 0.296 0.000
T55 Toxic effect of soaps and detergents
0.704 0.296 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.704 0.296 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.296 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.704 0.296 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.704 0.296 0.000
T36 Poisoning by systemic antibiotics
0.704 0.296 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.703 0.297 0.000
D73 Diseases of spleen
0.703 0.297 0.000
M25.4 Effusion of joint
0.703 0.297 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.702 0.297 0.000
F09 Unspecified organic or symptomatic mental disorder
0.702 0.297 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.702 0.297 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.701 0.299 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.701 0.299 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.700 0.299 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.700 0.299 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.700 0.299 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.700 0.299 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.700 0.299 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.700 0.299 0.000
F11 Mental and behavioural disorders due to use of opioids
0.700 0.299 0.000
C50-C50 Malignant neoplasm of breast
0.700 0.300 0.000
G62.8 Other specified polyneuropathies
0.700 0.300 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.699 0.301 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.696 0.304 0.000
F10.9 Unspecified mental and behavioural disorder
0.696 0.304 0.000
F10.8 Other mental and behavioural disorders
0.696 0.304 0.000
F10.7 Residual and late-onset psychotic disorder
0.696 0.304 0.000
F10.6 Amnesic syndrome
0.696 0.304 0.000
F10.5 Psychotic disorder
0.696 0.304 0.000
C83.3 Large cell (diffuse)
0.695 0.304 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.695 0.305 0.000
F25 Schizoaffective disorders
0.694 0.305 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.694 0.306 0.000
L10-L14 Bullous disorders
0.693 0.307 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.693 0.307 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.693 0.307 0.000
T39.1 4-Aminophenol derivatives
0.692 0.308 0.000
L01 Impetigo
0.692 0.308 0.000
L00 Staphylococcal scalded skin syndrome
0.692 0.308 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.691 0.309 0.000
A80-A89 Viral infections of the central nervous system
0.691 0.309 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.690 0.310 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.690 0.310 0.000
D74 Methaemoglobinaemia
0.690 0.310 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.690 0.310 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.690 0.310 0.000
C73 Malignant neoplasm of thyroid gland
0.689 0.311 0.000
D04 Carcinoma in situ of skin
0.689 0.311 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.688 0.312 0.000
M40-M43 Deforming dorsopathies
0.686 0.313 0.000
M07 Psoriatic and enteropathic arthropathies
0.686 0.314 0.000
S82.61 Fracture of lateral malleolus (open)
0.686 0.314 0.000
C80 Malignant neoplasm without specification of site
0.686 0.314 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.685 0.315 0.000
A40.2 Septicaemia due to streptococcus, group D
0.685 0.315 0.000
D03 Melanoma in situ
0.683 0.317 0.000
F32 Depressive episode
0.682 0.318 0.000
Q60-Q64 Congenital malformations of the urinary system
0.680 0.320 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.679 0.320 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.679 0.320 0.000
S52 Fracture of forearm
0.679 0.321 0.000
L43 Lichen planus
0.679 0.321 0.000
A08 Viral and other specified intestinal infections
0.679 0.321 0.000
T51.8 Other alcohols
0.679 0.321 0.000
T51.3 Fusel oil
0.679 0.321 0.000
T51.2 2-Propanol
0.679 0.321 0.000
T51.1 Methanol
0.679 0.321 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.678 0.322 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.677 0.323 0.000
C64-C68 Malignant neoplasms of urinary tract
0.676 0.324 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.676 0.324 0.000
S81.0 Open wound of knee
0.675 0.324 0.000
M10.94 Gout, unspecified (Hand)
0.675 0.324 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.675 0.325 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.675 0.325 0.000
G95.2 Cord compression, unspecified
0.675 0.325 0.000
F05.8 Other delirium
0.674 0.326 0.000
F05.1 Delirium superimposed on dementia
0.674 0.326 0.000
F05.0 Delirium not superimposed on dementia, so described
0.674 0.326 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.673 0.327 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.672 0.328 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.672 0.328 0.000
F80-F89 Disorders of psychological development
0.670 0.330 0.000
T93 Sequelae of injuries of lower limb
0.670 0.330 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.669 0.331 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.669 0.331 0.000
T83.2 Mechanical complication of graft of urinary organ
0.669 0.331 0.000
L40.5 Arthropathic psoriasis
0.669 0.331 0.000
D48.7 Other specified sites
0.669 0.331 0.000
G44 Other headache syndromes
0.668 0.331 0.000
T86 Failure and rejection of transplanted organs and tissues
0.667 0.333 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.667 0.333 0.000
F31 Bipolar affective disorder
0.667 0.333 0.000
A07 Other protozoal intestinal diseases
0.666 0.334 0.000
A06 Amoebiasis
0.666 0.334 0.000
A05 Other bacterial foodborne intoxications
0.666 0.334 0.000
A03 Shigellosis
0.666 0.334 0.000
A02 Other Salmonella infections
0.666 0.334 0.000
A01 Typhoid and paratyphoid fevers
0.666 0.334 0.000
A00 Cholera
0.666 0.334 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.665 0.335 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.664 0.336 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.664 0.336 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.664 0.336 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.664 0.336 0.000
S31 Open wound of abdomen, lower back and pelvis
0.664 0.336 0.000
M25.50 Pain in joint (Multiple sites)
0.664 0.336 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.663 0.336 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.662 0.338 0.000
X00-X09 Exposure to smoke, fire and flames
0.662 0.338 0.000
M25.53 Pain in joint (Forearm)
0.662 0.338 0.000
S81.7 Multiple open wounds of lower leg
0.661 0.339 0.000
F29 Unspecified nonorganic psychosis
0.660 0.340 0.000
A04.8 Other specified bacterial intestinal infections
0.660 0.340 0.000
G64 Other disorders of peripheral nervous system
0.660 0.340 0.000
V80-V89 Other land transport accidents
0.659 0.341 0.000
S89 Other and unspecified injuries of lower leg
0.658 0.342 0.000
M22 Disorders of patella
0.658 0.342 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.657 0.343 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.656 0.344 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.656 0.344 0.000
T39.4 Antirheumatics, not elsewhere classified
0.656 0.344 0.000
T39.2 Pyrazolone derivatives
0.656 0.344 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.655 0.344 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.655 0.344 0.000
L05.0 Pilonidal cyst with abscess
0.655 0.345 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.655 0.345 0.000
M34 Systemic sclerosis
0.654 0.346 0.000
T87 Complications peculiar to reattachment and amputation
0.653 0.347 0.000
M60-M63 Disorders of muscles
0.652 0.348 0.000
G93 Other disorders of brain
0.652 0.348 0.000
A49.3 Mycoplasma infection, unspecified
0.651 0.349 0.000
A49.2 Haemophilus influenzae infection, unspecified
0.651 0.349 0.000
D62 Acute posthaemorrhagic anaemia
0.651 0.349 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.650 0.349 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.650 0.350 0.000
M25.46 Effusion of joint (Lower leg)
0.648 0.352 0.000
G91.1 Obstructive hydrocephalus
0.648 0.352 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.648 0.352 0.000
D64.9 Anaemia, unspecified
0.648 0.352 0.000
S82.31 Fracture of lower end of tibia (open)
0.647 0.353 0.000
S82.4 Fracture of fibula alone
0.646 0.353 0.000
Y00-Y09 Assault
0.646 0.354 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.646 0.354 0.000
S32.0 Fracture of lumbar vertebra
0.645 0.355 0.000
C01 Malignant neoplasm of base of tongue
0.645 0.355 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.644 0.356 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.644 0.356 0.000
G92 Toxic encephalopathy
0.644 0.356 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.644 0.356 0.000
D48.4 Peritoneum
0.644 0.356 0.000
D48.3 Retroperitoneum
0.644 0.356 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.644 0.356 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.643 0.357 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.642 0.358 0.000
B34 Viral infection of unspecified site
0.641 0.359 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.641 0.359 0.000
G62.0 Drug-induced polyneuropathy
0.640 0.360 0.000
S50.0 Contusion of elbow
0.640 0.360 0.000
M14 Arthropathies in other diseases classified elsewhere
0.639 0.361 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.639 0.361 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.639 0.361 0.000
L05.9 Pilonidal cyst without abscess
0.638 0.362 0.000
M10.90 Gout, unspecified (Multiple sites)
0.638 0.362 0.000
S32.5 Fracture of pubis
0.638 0.362 0.000
M06 Other rheumatoid arthritis
0.638 0.362 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.637 0.362 0.000
T43.9 Psychotropic drug, unspecified
0.637 0.363 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.637 0.363 0.000
T43.6 Psychostimulants with abuse potential
0.637 0.363 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.637 0.363 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.637 0.363 0.000
G91.2 Normal-pressure hydrocephalus
0.637 0.363 0.000
D37.0 Lip, oral cavity and pharynx
0.637 0.363 0.000
S29 Other and unspecified injuries of thorax
0.637 0.363 0.000
M89.9 Disorder of bone, unspecified
0.636 0.363 0.000
T81.9 Unspecified complication of procedure
0.636 0.364 0.000
M24 Other specific joint derangements
0.636 0.364 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.636 0.364 0.000
Q35-Q37 Cleft lip and cleft palate
0.636 0.364 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.636 0.364 0.000
M21.0 Valgus deformity, not elsewhere classified
0.635 0.365 0.000
D48.5 Skin
0.635 0.365 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.635 0.365 0.000
L04.9 Acute lymphadenitis, unspecified
0.634 0.366 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.633 0.367 0.000
G95.9 Disease of spinal cord, unspecified
0.632 0.368 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.632 0.368 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.632 0.368 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.631 0.368 0.000
S82.11 Fracture of upper end of tibia (open)
0.631 0.369 0.000
D80-D89 Certain disorders involving the immune mechanism
0.631 0.369 0.000
A04.9 Bacterial intestinal infection, unspecified
0.630 0.370 0.000
S59 Other and unspecified injuries of forearm
0.629 0.371 0.000
S58 Traumatic amputation of forearm
0.629 0.371 0.000
S57 Crushing injury of forearm
0.629 0.371 0.000
S55 Injury of blood vessels at forearm level
0.629 0.371 0.000
S54 Injury of nerves at forearm level
0.629 0.371 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.629 0.371 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.629 0.371 0.000
C95 Leukaemia of unspecified cell type
0.629 0.371 0.000
C94 Other leukaemias of specified cell type
0.629 0.371 0.000
C93 Monocytic leukaemia
0.629 0.371 0.000
C86 Other specified types of T/NK-cell lymphoma
0.629 0.371 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.629 0.371 0.000
M87 Osteonecrosis
0.628 0.372 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.627 0.372 0.000
T82.3 Mechanical complication of other vascular grafts
0.627 0.373 0.000
S27 Injury of other and unspecified intrathoracic organs
0.627 0.373 0.000
D50-D53 Nutritional anaemias
0.627 0.373 0.000
F22.0 Delusional disorder
0.626 0.374 0.000
M12 Other specific arthropathies
0.625 0.375 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.625 0.375 0.000
M08 Juvenile arthritis
0.625 0.375 0.000
D75.2 Essential thrombocytosis
0.625 0.375 0.000
D75.0 Familial erythrocytosis
0.625 0.375 0.000
M31.6 Other giant cell arteritis
0.625 0.375 0.000
C90.2 Plasmacytoma, extramedullary
0.625 0.375 0.000
M11 Other crystal arthropathies
0.625 0.375 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.624 0.375 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.624 0.376 0.000
T79-T79 Certain early complications of trauma
0.624 0.376 0.000
Q80-Q89 Other congenital malformations
0.624 0.376 0.000
S40-S49 Injuries to the shoulder and upper arm
0.624 0.376 0.000
M05 Seropositive rheumatoid arthritis
0.623 0.377 0.000
G00 Bacterial meningitis, not elsewhere classified
0.623 0.377 0.000
D44.3 Pituitary gland
0.623 0.377 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.622 0.378 0.000
C76.2 Abdomen
0.620 0.380 0.000
G91.9 Hydrocephalus, unspecified
0.620 0.380 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.619 0.381 0.000
M00-M03 Infectious arthropathies
0.619 0.381 0.000
C91 Lymphoid leukaemia
0.619 0.381 0.000
G90 Disorders of autonomic nervous system
0.618 0.381 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.618 0.382 0.000
M66 Spontaneous rupture of synovium and tendon
0.618 0.382 0.000
A39.0 Meningococcal meningitis
0.618 0.382 0.000
L03.0 Cellulitis of finger and toe
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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