TreeWAS – Variant ID: rs3738443

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.040	0.960	0.000
O14.0 Moderate preeclampsia	0.040	0.960	0.000
O14.9 Preeclampsia, unspecified	0.037	0.963	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.037	0.963	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.033	0.967	0.000
O14.1 Severe preeclampsia	0.033	0.967	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.032	0.968	0.000
O16 Unspecified maternal hypertension	0.031	0.969	0.000
O14.2 HELLP syndrome	0.029	0.971	0.000
O12.1 Gestational proteinuria	0.028	0.972	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.028	0.972	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.028	0.972	0.000
O12.0 Gestational oedema	0.028	0.972	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.028	0.972	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.028	0.972	0.000
O15 Eclampsia	0.026	0.973	0.000
O12.2 Gestational oedema with proteinuria	0.024	0.976	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.023	0.977	0.000
O15.9 Eclampsia, unspecified as to time period	0.019	0.981	0.000
O15.2 Eclampsia in the puerperium	0.019	0.981	0.000
O15.1 Eclampsia in labour	0.019	0.981	0.000
O15.0 Eclampsia in pregnancy	0.019	0.981	0.000
S06 Intracranial injury	0.014	0.986	0.000
S06.5 Traumatic subdural haemorrhage	0.014	0.986	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.014	0.986	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.013	0.986	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.013	0.987	0.000
S06.8 Other intracranial injuries	0.013	0.987	0.000
S06.4 Epidural haemorrhage	0.012	0.988	0.000
S06.2 Diffuse brain injury	0.012	0.988	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.012	0.988	0.000
S06.9 Intracranial injury, unspecified	0.011	0.989	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.011	0.989	0.000
E05.9 Thyrotoxicosis, unspecified	0.011	0.989	0.000
S06.0 Concussion	0.011	0.989	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.011	0.989	0.000
S06.7 Intracranial injury with prolonged coma	0.010	0.989	0.000
S06.1 Traumatic cerebral oedema	0.010	0.989	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.010	0.990	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.010	0.990	0.000
S06.3 Focal brain injury	0.010	0.990	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.010	0.990	0.000
N30.9 Cystitis, unspecified	0.010	0.990	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.009	0.991	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.009	0.991	0.000
S02 Fracture of skull and facial bones	0.009	0.991	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.009	0.991	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.009	0.991	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.009	0.991	0.000
S00-S09 Injuries to the head	0.009	0.991	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.009	0.991	0.000
S02.0 Fracture of vault of skull	0.009	0.991	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.008	0.991	0.000
S02.00 Fracture of vault of skull (closed)	0.008	0.992	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.008	0.992	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.008	0.992	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.008	0.992	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.008	0.992	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.008	0.992	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.008	0.992	0.000
S02.2 Fracture of nasal bones	0.008	0.992	0.000
S02.3 Fracture of orbital floor	0.008	0.992	0.000
S06.00 Concussion (without open intracranial wound)	0.008	0.992	0.000
S06.01 Concussion (with open intracranial wound)	0.008	0.992	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.008	0.992	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.008	0.992	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.008	0.992	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.008	0.992	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.008	0.992	0.000
M67.8 Other specified disorders of synovium and tendon	0.008	0.992	0.000
S02.1 Fracture of base of skull	0.008	0.992	0.000
S02.30 Fracture of orbital floor (closed)	0.008	0.992	0.000
S05 Injury of eye and orbit	0.008	0.992	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.007	0.992	0.000
G56.0 Carpal tunnel syndrome	0.008	0.992	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.007	0.993	0.000
O20.0 Threatened abortion	0.000	0.993	0.007
S06.31 Focal brain injury (with open intracranial wound)	0.007	0.993	0.000
S02.21 Fracture of nasal bones (open)	0.007	0.993	0.000
S02.7 Multiple fractures involving skull and facial bones	0.007	0.993	0.000
S02.20 Fracture of nasal bones (closed)	0.007	0.993	0.000
S02.8 Fractures of other skull and facial bones	0.007	0.993	0.000
E05.5 Thyroid crisis or storm	0.007	0.993	0.000
E05.4 Thyrotoxicosis factitia	0.007	0.993	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.007	0.993	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.007	0.993	0.000
S02.10 Fracture of base of skull (closed)	0.007	0.993	0.000
S02.5 Fracture of tooth	0.007	0.993	0.000
E05.8 Other thyrotoxicosis	0.007	0.993	0.000
S08 Traumatic amputation of part of head	0.007	0.993	0.000
S07 Crushing injury of head	0.007	0.993	0.000
S04 Injury of cranial nerves	0.007	0.993	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.007	0.993	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.006	0.993	0.000
S02.01 Fracture of vault of skull (open)	0.006	0.993	0.000
E07.9 Disorder of thyroid, unspecified	0.006	0.994	0.000
S00 Superficial injury of head	0.006	0.994	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.006	0.994	0.000
S05.8 Other injuries of eye and orbit	0.006	0.994	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.006	0.994	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.006	0.994	0.000
S02.31 Fracture of orbital floor (open)	0.006	0.994	0.000
S00.1 Contusion of eyelid and periocular area	0.006	0.994	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.006	0.994	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.006	0.994	0.000
T78.2 Anaphylactic shock, unspecified	0.006	0.994	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.994	0.006
S02.11 Fracture of base of skull (open)	0.006	0.994	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.994	0.006
E07 Other disorders of thyroid	0.006	0.994	0.000
S05.7 Avulsion of eye	0.006	0.994	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.006	0.994	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.006	0.994	0.000
E00-E07 Disorders of thyroid gland	0.006	0.994	0.000
M67 Other disorders of synovium and tendon	0.006	0.994	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.994	0.006
S02.70 Multiple fractures involving skull and facial bones (closed)	0.005	0.994	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.006	0.994	0.000
S09 Other and unspecified injuries of head	0.006	0.994	0.000
C77.9 Lymph node, unspecified	0.000	0.995	0.005
C77.8 Lymph nodes of multiple regions	0.000	0.995	0.005
H34.8 Other retinal vascular occlusions	0.005	0.995	0.000
S02.6 Fracture of mandible	0.005	0.995	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.005	0.995	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.005	0.995	0.000
M46 Other inflammatory spondylopathies	0.005	0.995	0.000
S02.81 Fractures of other skull and facial bones (open)	0.005	0.995	0.000
M67.0 Short Achilles tendon (acquired)	0.005	0.995	0.000
S02.51 Fracture of tooth (open)	0.005	0.995	0.000
S05.9 Injury of eye and orbit, part unspecified	0.005	0.995	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.005	0.995	0.000
S03.4 Sprain and strain of jaw	0.005	0.995	0.000
S03.3 Dislocation of other and unspecified parts of head	0.005	0.995	0.000
S03.2 Dislocation of tooth	0.005	0.995	0.000
S03.1 Dislocation of septal cartilage of nose	0.005	0.995	0.000
S03.0 Dislocation of jaw	0.005	0.995	0.000
S04.9 Injury of unspecified cranial nerve	0.005	0.995	0.000
S04.8 Injury of other cranial nerves	0.005	0.995	0.000
S04.7 Injury of accessory nerve	0.005	0.995	0.000
S04.6 Injury of acoustic nerve	0.005	0.995	0.000
S04.5 Injury of facial nerve	0.005	0.995	0.000
S04.4 Injury of abducent nerve	0.005	0.995	0.000
S04.3 Injury of trigeminal nerve	0.005	0.995	0.000
S04.2 Injury of trochlear nerve	0.005	0.995	0.000
S04.1 Injury of oculomotor nerve	0.005	0.995	0.000
S04.0 Injury of optic nerve and pathways	0.005	0.995	0.000
S07.9 Crushing injury of head, part unspecified	0.005	0.995	0.000
S07.8 Crushing injury of other parts of head	0.005	0.995	0.000
S07.1 Crushing injury of skull	0.005	0.995	0.000
S07.0 Crushing injury of face	0.005	0.995	0.000
S08.9 Traumatic amputation of unspecified part of head	0.005	0.995	0.000
S08.8 Traumatic amputation of other parts of head	0.005	0.995	0.000
S08.1 Traumatic amputation of ear	0.005	0.995	0.000
S08.0 Avulsion of scalp	0.005	0.995	0.000
M67.1 Other contracture of tendon (sheath)	0.005	0.995	0.000
S05.1 Contusion of eyeball and orbital tissues	0.005	0.995	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.005	0.995	0.000
S02.50 Fracture of tooth (closed)	0.005	0.995	0.000
E04.0 Non-toxic diffuse goitre	0.005	0.995	0.000
S02.4 Fracture of malar and maxillary bones	0.005	0.995	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.995	0.005
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.004	0.995	0.000
M67.4 Ganglion	0.005	0.995	0.000
H34 Retinal vascular occlusions	0.005	0.995	0.000
T78 Adverse effects, not elsewhere classified	0.005	0.995	0.000
S09.2 Traumatic rupture of ear drum	0.004	0.995	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.004	0.996	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.004	0.996	0.000
E07.1 Dyshormogenetic goitre	0.004	0.996	0.000
E07.0 Hypersecretion of calcitonin	0.004	0.996	0.000
M46.0 Spinal enthesopathy	0.004	0.996	0.000
S00.0 Superficial injury of scalp	0.004	0.996	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.004	0.996	0.000
E00 Congenital iodine-deficiency syndrome	0.004	0.996	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.004	0.996	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.996	0.004
H34.2 Other retinal artery occlusions	0.004	0.996	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.004	0.996	0.000
M67.3 Transient synovitis	0.004	0.996	0.000
H34.1 Central retinal artery occlusion	0.004	0.996	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.996	0.004
S09.7 Multiple injuries of head	0.004	0.996	0.000
S09.1 Injury of muscle and tendon of head	0.004	0.996	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.996	0.004
E03.8 Other specified hypothyroidism	0.004	0.996	0.000
E03 Other hypothyroidism	0.004	0.996	0.000
S02.61 Fracture of mandible (open)	0.004	0.996	0.000
M46.8 Other specified inflammatory spondylopathies	0.004	0.996	0.000
M46.5 Other infective spondylopathies	0.004	0.996	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.004	0.996	0.000
M46.2 Osteomyelitis of vertebra	0.004	0.996	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.004	0.996	0.000
E04 Other non-toxic goitre	0.004	0.996	0.000
M67.43 Ganglion, wrist	0.004	0.996	0.000
E06 Thyroiditis	0.004	0.996	0.000
S00.5 Superficial injury of lip and oral cavity	0.004	0.996	0.000
S00.8 Superficial injury of other parts of head	0.004	0.996	0.000
S00.4 Superficial injury of ear	0.004	0.996	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.004	0.996	0.000
H34.9 Retinal vascular occlusion, unspecified	0.004	0.996	0.000
U80.0 Penicillin resistant agent	0.004	0.996	0.000
S00.7 Multiple superficial injuries of head	0.004	0.996	0.000
E07.8 Other specified disorders of thyroid	0.004	0.996	0.000
G95.1 Vascular myelopathies	0.004	0.996	0.000
M46.4 Discitis, unspecified	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.004	0.996	0.000
G95.9 Disease of spinal cord, unspecified	0.004	0.996	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.004	0.996	0.000
T78.8 Other adverse effects, not elsewhere classified	0.004	0.996	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.003	0.996	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
S00.3 Superficial injury of nose	0.004	0.996	0.000
T78.3 Angioneurotic oedema	0.004	0.996	0.000
S09.8 Other specified injuries of head	0.003	0.996	0.000
M67.49 Ganglion, multiple sites	0.003	0.996	0.000
M67.45 Ganglion, hip	0.003	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.004	0.996	0.000
H34.0 Transient retinal artery occlusion	0.003	0.996	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.996	0.004
T78.9 Adverse effect, unspecified	0.003	0.996	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.003	0.996	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.003	0.997	0.000
M46.09 Spinal enthesopathy (Site unspecified)	0.003	0.997	0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M46.07 Spinal enthesopathy (Lumbosacral region)	0.003	0.997	0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)	0.003	0.997	0.000
M46.04 Spinal enthesopathy (Thoracic region)	0.003	0.997	0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)	0.003	0.997	0.000
M46.02 Spinal enthesopathy (Cervical region)	0.003	0.997	0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)	0.003	0.997	0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)	0.003	0.997	0.000
H57.0 Anomalies of pupillary function	0.003	0.997	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.003	0.997	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.003	0.997	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.003	0.997	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.003	0.997	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.997	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.003	0.997	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.003	0.997	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.003	0.997	0.000
T66-T78 Other and unspecified effects of external causes	0.003	0.997	0.000
M67.47 Ganglion, ankle and foot	0.003	0.997	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.003	0.997	0.000
C77.2 Intra-abdominal lymph nodes	0.000	0.997	0.003
E06.3 Autoimmune thyroiditis	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
T68 Hypothermia	0.003	0.997	0.000
G95 Other diseases of spinal cord	0.003	0.997	0.000
M23.3 Other meniscus derangements	0.000	0.997	0.003
E03.5 Myxoedema coma	0.003	0.997	0.000
E03.4 Atrophy of thyroid (acquired)	0.003	0.997	0.000
E03.3 Postinfectious hypothyroidism	0.003	0.997	0.000
E03.1 Congenital hypothyroidism without goitre	0.003	0.997	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.003	0.997	0.000
G95.8 Other specified diseases of spinal cord	0.003	0.997	0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe	0.003	0.997	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.003	0.997	0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral	0.003	0.997	0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar	0.003	0.997	0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar	0.003	0.997	0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic	0.003	0.997	0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic	0.003	0.997	0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical	0.003	0.997	0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl	0.003	0.997	0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site	0.003	0.997	0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)	0.003	0.997	0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)	0.003	0.997	0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)	0.003	0.997	0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)	0.003	0.997	0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)	0.003	0.997	0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)	0.003	0.997	0.000
M46.22 Osteomyelitis of vertebra (Cervical region)	0.003	0.997	0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)	0.003	0.997	0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)	0.003	0.997	0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)	0.003	0.997	0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)	0.003	0.997	0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)	0.003	0.997	0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)	0.003	0.997	0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)	0.003	0.997	0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)	0.003	0.997	0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)	0.003	0.997	0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)	0.003	0.997	0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)	0.003	0.997	0.000
M46.59 Other infective spondylopathies (Site unspecified)	0.003	0.997	0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M46.57 Other infective spondylopathies (Lumbosacral region)	0.003	0.997	0.000
M46.56 Other infective spondylopathies (Lumbar region)	0.003	0.997	0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)	0.003	0.997	0.000
M46.54 Other infective spondylopathies (Thoracic region)	0.003	0.997	0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)	0.003	0.997	0.000
M46.52 Other infective spondylopathies (Cervical region)	0.003	0.997	0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)	0.003	0.997	0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)	0.003	0.997	0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)	0.003	0.997	0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)	0.003	0.997	0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)	0.003	0.997	0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)	0.003	0.997	0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)	0.003	0.997	0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)	0.003	0.997	0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)	0.003	0.997	0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)	0.003	0.997	0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)	0.003	0.997	0.000
E04.8 Other specified non-toxic goitre	0.003	0.997	0.000
E06.5 Other chronic thyroiditis	0.003	0.997	0.000
E06.4 Drug-induced thyroiditis	0.003	0.997	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.003	0.997	0.000
E06.1 Subacute thyroiditis	0.003	0.997	0.000
E06.0 Acute thyroiditis	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.997	0.003
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
M46.44 Discitis, unspecified (Thoracic region)	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
K14.8 Other diseases of tongue	0.000	0.997	0.003
M46.49 Discitis, unspecified (Site unspecified)	0.003	0.997	0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M46.47 Discitis, unspecified (Lumbosacral region)	0.003	0.997	0.000
M46.45 Discitis, unspecified (Thoracolumbar region)	0.003	0.997	0.000
M46.43 Discitis, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M46.42 Discitis, unspecified (Cervical region)	0.003	0.997	0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
M46.40 Discitis, unspecified (Multiple sites in spine)	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
R80 Isolated proteinuria	0.003	0.997	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
D89.3 Immune reconstitution syndrome	0.003	0.997	0.000
D89.1 Cryoglobulinaemia	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.003	0.997	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.003	0.997	0.000
T70 Effects of air pressure and water pressure	0.003	0.997	0.000
K83.1 Obstruction of bile duct	0.000	0.997	0.003
T75 Effects of other external causes	0.003	0.997	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.000	0.997	0.003
S09.9 Unspecified injury of head	0.003	0.997	0.000
U89.8 Agent resistant to other single specified antibiotic	0.003	0.997	0.000
S01 Open wound of head	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.003	0.997	0.000
T66 Unspecified effects of radiation	0.003	0.997	0.000
Q61 Cystic kidney disease	0.000	0.997	0.003
D86 Sarcoidosis	0.003	0.997	0.000
T74 Maltreatment syndromes	0.003	0.997	0.000
T73 Effects of other deprivation	0.003	0.997	0.000
T69 Other effects of reduced temperature	0.003	0.997	0.000
T67 Effects of heat and light	0.003	0.997	0.000
T71 Asphyxiation	0.003	0.997	0.000
G95.0 Syringomyelia and syringobulbia	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.003	0.997	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.003	0.997	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.003	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.003	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.003	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.003	0.997	0.000
S29.9 Unspecified injury of thorax	0.003	0.997	0.000
M23.37 Other meniscus derangements-Capsular lig	0.000	0.997	0.002
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.000	0.997	0.003
E04.1 Non-toxic single thyroid nodule	0.003	0.997	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.003	0.997	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
S02.60 Fracture of mandible (closed)	0.002	0.997	0.000
C22.0 Liver cell carcinoma	0.003	0.997	0.000
S01.1 Open wound of eyelid and periocular area	0.003	0.997	0.000
T70.3 Caisson disease [decompression sickness]	0.002	0.997	0.000
R87.6 Abnormal cytological findings	0.003	0.997	0.000
S01.4 Open wound of cheek and temporomandibular area	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
T75.4 Effects of electric current	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
R82 Other abnormal findings in urine	0.002	0.998	0.000
W19.2 School, other institution and public administrative area	0.002	0.998	0.000
U80 Agent resistant to penicillin and related antibiotics	0.002	0.998	0.000
S01.9 Open wound of head, part unspecified	0.002	0.998	0.000
C22.9 Liver, unspecified	0.002	0.998	0.000
Y40.0 Penicillins	0.000	0.998	0.002
T70.9 Effect of air pressure and water pressure, unspecified	0.002	0.998	0.000
T70.8 Other effects of air pressure and water pressure	0.002	0.998	0.000
T70.4 Effects of high-pressure fluids	0.002	0.998	0.000
T70.2 Other and unspecified effects of high altitude	0.002	0.998	0.000
T70.1 Sinus barotrauma	0.002	0.998	0.000
T70.0 Otitic barotrauma	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
T75.8 Other specified effects of external causes	0.002	0.998	0.000
T75.3 Motion sickness	0.002	0.998	0.000
T75.2 Effects of vibration	0.002	0.998	0.000
T75.1 Drowning and nonfatal submersion	0.002	0.998	0.000
T75.0 Effects of lightning	0.002	0.998	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.002	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.002	0.998	0.000
L81.9 Disorder of pigmentation, unspecified	0.002	0.998	0.000
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.4 Renal dysplasia	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
R82.8 Abnormal findings on cytological and histological examination of urine	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
T67.9 Effects of heat and light, unspecified	0.002	0.998	0.000
T67.8 Other effects of heat and light	0.002	0.998	0.000
T67.7 Heat oedema	0.002	0.998	0.000
T67.6 Heat fatigue, transient	0.002	0.998	0.000
T67.5 Heat exhaustion, unspecified	0.002	0.998	0.000
T67.4 Heat exhaustion due to salt depletion	0.002	0.998	0.000
T67.3 Heat exhaustion, anhydrotic	0.002	0.998	0.000
T67.2 Heat cramp	0.002	0.998	0.000
T67.1 Heat syncope	0.002	0.998	0.000
T67.0 Heatstroke and sunstroke	0.002	0.998	0.000
T69.9 Effect of reduced temperature, unspecified	0.002	0.998	0.000
T69.8 Other specified effects of reduced temperature	0.002	0.998	0.000
T69.1 Chilblains	0.002	0.998	0.000
T69.0 Immersion hand and foot	0.002	0.998	0.000
T73.9 Effect of deprivation, unspecified	0.002	0.998	0.000
T73.8 Other effects of deprivation	0.002	0.998	0.000
T73.3 Exhaustion due to excessive exertion	0.002	0.998	0.000
T73.2 Exhaustion due to exposure	0.002	0.998	0.000
T73.1 Effects of thirst	0.002	0.998	0.000
T73.0 Effects of hunger	0.002	0.998	0.000
T74.9 Maltreatment syndrome, unspecified	0.002	0.998	0.000
T74.8 Other maltreatment syndromes	0.002	0.998	0.000
T74.3 Psychological abuse	0.002	0.998	0.000
T74.2 Sexual abuse	0.002	0.998	0.000
T74.1 Physical abuse	0.002	0.998	0.000
T74.0 Neglect or abandonment	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
H52.0 Hypermetropia	0.000	0.998	0.002
S01.3 Open wound of ear	0.002	0.998	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
U89 Agent resistant to other and unspecified antibiotics	0.002	0.998	0.000
L43.9 Lichen planus, unspecified	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
L89.1 Stage II decubitus ulcer	0.000	0.998	0.002
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
F03 Unspecified dementia	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.002	0.998	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.002	0.998	0.000
R82.3 Haemoglobinuria	0.002	0.998	0.000
R82.2 Biliuria	0.002	0.998	0.000
R82.1 Myoglobinuria	0.002	0.998	0.000
R82.0 Chyluria	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
E04.9 Non-toxic goitre, unspecified	0.002	0.998	0.000
H53.2 Diplopia	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
S00.9 Superficial injury of head, part unspecified	0.002	0.998	0.000
R82.4 Acetonuria	0.002	0.998	0.000
S01.7 Multiple open wounds of head	0.002	0.998	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
S01.5 Open wound of lip and oral cavity	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.002	0.998	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.998	0.002
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.002	0.998	0.000
H57 Other disorders of eye and adnexa	0.002	0.998	0.000
R87.9 Unspecified abnormal finding	0.002	0.998	0.000
R87 Abnormal findings in specimens from female genital organs	0.002	0.998	0.000
U89.9 Agent resistant to unspecified antibiotic	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.998	0.000
S29 Other and unspecified injuries of thorax	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations