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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3753573
log Bayes Factor = 2.28353
Chromosome 1   position 185,014,002  (GRCh37) Explore rs3753573 on Ensembl!
Variant rs3753573 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.995 0.005 0.000
Chapter XIV Diseases of the genitourinary system
0.988 0.012 0.000
N40-N51 Diseases of male genital organs
0.984 0.016 0.000
N40 Hyperplasia of prostate
0.980 0.020 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.972 0.028 0.000
Chapter X Diseases of the respiratory system
0.944 0.056 0.000
Chapter VI Diseases of the nervous system
0.921 0.079 0.000
Chapter II Neoplasms
0.890 0.110 0.000
J30-J39 Other diseases of upper respiratory tract
0.882 0.118 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.861 0.139 0.000
Chapter V Mental and behavioural disorders
0.861 0.139 0.000
Chapter VII Diseases of the eye and adnexa
0.855 0.145 0.000
R30-R39 Symptoms and signs involving the urinary system
0.843 0.157 0.000
G40-G47 Episodic and paroxysmal disorders
0.833 0.167 0.000
J34 Other disorders of nose and nasal sinuses
0.817 0.183 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.813 0.187 0.000
N30-N39 Other diseases of urinary system
0.808 0.192 0.000
R50-R69 General symptoms and signs
0.807 0.193 0.000
Chapter IX Diseases of the circulatory system
0.804 0.196 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.804 0.196 0.000
Chapter XI Diseases of the digestive system
0.804 0.196 0.000
N20-N23 Urolithiasis
0.793 0.207 0.000
N41 Inflammatory diseases of prostate
0.793 0.207 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.793 0.207 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.780 0.220 0.000
C60-C63 Malignant neoplasms of male genital organs
0.767 0.233 0.000
Chapter I Certain infectious and parasitic diseases
0.764 0.236 0.000
J90-J94 Other diseases of pleura
0.751 0.249 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.750 0.250 0.000
D10-D36 Benign neoplasms
0.750 0.250 0.000
R32 Unspecified urinary incontinence
0.749 0.251 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.746 0.254 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.737 0.263 0.000
J20-J22 Other acute lower respiratory infections
0.729 0.271 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.727 0.273 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.725 0.275 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.724 0.275 0.000
R51 Headache
0.722 0.278 0.000
J34.2 Deviated nasal septum
0.718 0.282 0.000
N50 Other disorders of male genital organs
0.717 0.283 0.000
J33 Nasal polyp
0.713 0.286 0.000
Chapter XXII Codes for special purposes
0.713 0.287 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.713 0.287 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.713 0.287 0.000
Chapter VIII Diseases of the ear and mastoid process
0.713 0.287 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.713 0.287 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.712 0.288 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.712 0.288 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.710 0.290 0.000
F30-F39 Mood [affective] disorders
0.709 0.291 0.000
N99-N99 Other disorders of the genitourinary system
0.708 0.292 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.708 0.292 0.000
N60-N64 Disorders of breast
0.708 0.292 0.000
N25-N29 Other disorders of kidney and ureter
0.708 0.292 0.000
N10-N16 Renal tubulo-interstitial diseases
0.708 0.292 0.000
N00-N08 Glomerular diseases
0.708 0.292 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.706 0.293 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.705 0.295 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.705 0.295 0.000
N48 Other disorders of penis
0.705 0.295 0.000
N45 Orchitis and epididymitis
0.705 0.295 0.000
N43 Hydrocele and spermatocele
0.705 0.295 0.000
N42 Other disorders of prostate
0.705 0.295 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.705 0.295 0.000
N46 Male infertility
0.705 0.295 0.000
N44 Torsion of testis
0.705 0.295 0.000
H30-H36 Disorders of choroid and retina
0.703 0.297 0.000
I30-I52 Other forms of heart disease
0.700 0.300 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.697 0.303 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.697 0.303 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.697 0.303 0.000
R47-R49 Symptoms and signs involving speech and voice
0.697 0.303 0.000
R33 Retention of urine
0.691 0.309 0.000
R35 Polyuria
0.689 0.311 0.000
K50-K52 Noninfective enteritis and colitis
0.688 0.312 0.000
J95-J99 Other diseases of the respiratory system
0.688 0.312 0.000
M20-M25 Other joint disorders
0.686 0.314 0.000
C61 Malignant neoplasm of prostate
0.679 0.321 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.679 0.321 0.000
N32 Other disorders of bladder
0.678 0.322 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.677 0.323 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.677 0.323 0.000
J60-J70 Lung diseases due to external agents
0.677 0.323 0.000
J00-J06 Acute upper respiratory infections
0.677 0.323 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.675 0.325 0.000
J40-J47 Chronic lower respiratory diseases
0.673 0.327 0.000
J09-J18 Influenza and pneumonia
0.671 0.329 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.669 0.331 0.000
I60-I69 Cerebrovascular diseases
0.668 0.332 0.000
S00-S09 Injuries to the head
0.667 0.333 0.000
Chapter XX External causes of morbidity and mortality
0.661 0.339 0.000
G90-G99 Other disorders of the nervous system
0.661 0.339 0.000
G70-G73 Diseases of myoneural junction and muscle
0.661 0.339 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.661 0.339 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.661 0.339 0.000
G30-G32 Other degenerative diseases of the nervous system
0.661 0.339 0.000
G20-G26 Extrapyramidal and movement disorders
0.661 0.339 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.661 0.339 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.661 0.339 0.000
N17-N19 Renal failure
0.659 0.341 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.658 0.342 0.000
N41.1 Chronic prostatitis
0.656 0.344 0.000
R26 Abnormalities of gait and mobility
0.655 0.345 0.000
G47 Sleep disorders
0.655 0.345 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.655 0.345 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.653 0.347 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.652 0.348 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.652 0.348 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.650 0.349 0.000
N20 Calculus of kidney and ureter
0.650 0.350 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.648 0.352 0.000
H25-H28 Disorders of lens
0.648 0.352 0.000
R04 Haemorrhage from respiratory passages
0.644 0.356 0.000
G40 Epilepsy
0.644 0.356 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.643 0.357 0.000
R05 Cough
0.640 0.360 0.000
S50-S59 Injuries to the elbow and forearm
0.640 0.360 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.638 0.362 0.000
D00-D09 In situ neoplasms
0.638 0.362 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.638 0.362 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.638 0.362 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.638 0.362 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.638 0.362 0.000
C64-C68 Malignant neoplasms of urinary tract
0.638 0.362 0.000
C51-C58 Malignant neoplasms of female genital organs
0.638 0.362 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.638 0.362 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.638 0.362 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.638 0.362 0.000
C15-C26 Malignant neoplasms of digestive organs
0.638 0.362 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.638 0.362 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.636 0.364 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.634 0.366 0.000
J39 Other diseases of upper respiratory tract
0.633 0.367 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.633 0.367 0.000
J37 Chronic laryngitis and laryngotracheitis
0.633 0.367 0.000
J35 Chronic diseases of tonsils and adenoids
0.633 0.367 0.000
J32 Chronic sinusitis
0.633 0.367 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.633 0.367 0.000
J30 Vasomotor and allergic rhinitis
0.633 0.367 0.000
J36 Peritonsillar abscess
0.633 0.367 0.000
R15 Faecal incontinence
0.629 0.371 0.000
G43 Migraine
0.629 0.371 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.625 0.375 0.000
I20-I25 Ischaemic heart diseases
0.623 0.377 0.000
K35-K38 Diseases of appendix
0.619 0.380 0.000
S80-S89 Injuries to the knee and lower leg
0.618 0.381 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.617 0.383 0.000
T79-T79 Certain early complications of trauma
0.617 0.383 0.000
T66-T78 Other and unspecified effects of external causes
0.617 0.383 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.617 0.383 0.000
T33-T35 Frostbite
0.617 0.383 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.617 0.383 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.617 0.383 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.617 0.383 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.617 0.383 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.617 0.383 0.000
T00-T07 Injuries involving multiple body regions
0.617 0.383 0.000
S90-S99 Injuries to the ankle and foot
0.617 0.383 0.000
S70-S79 Injuries to the hip and thigh
0.617 0.383 0.000
S60-S69 Injuries to the wrist and hand
0.617 0.383 0.000
S40-S49 Injuries to the shoulder and upper arm
0.617 0.383 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.617 0.383 0.000
S20-S29 Injuries to the thorax
0.617 0.383 0.000
S10-S19 Injuries to the neck
0.617 0.383 0.000
F99-F99 Unspecified mental disorder
0.617 0.383 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.617 0.383 0.000
F80-F89 Disorders of psychological development
0.617 0.383 0.000
F70-F79 Mental retardation
0.617 0.383 0.000
F60-F69 Disorders of adult personality and behaviour
0.617 0.383 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.617 0.383 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.617 0.383 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.617 0.383 0.000
M70-M79 Other soft tissue disorders
0.616 0.384 0.000
M50-M54 Other dorsopathies
0.614 0.385 0.000
R06 Abnormalities of breathing
0.614 0.386 0.000
N35 Urethral stricture
0.613 0.387 0.000
H55-H59 Other disorders of eye and adnexa
0.613 0.387 0.000
H53-H54 Visual disturbances and blindness
0.613 0.387 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.613 0.387 0.000
H43-H45 Disorders of vitreous body and globe
0.613 0.387 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.613 0.387 0.000
H10-H13 Disorders of conjunctiva
0.613 0.387 0.000
J90 Pleural effusion, not elsewhere classified
0.612 0.388 0.000
R00 Abnormalities of heart beat
0.607 0.393 0.000
K52 Other non-infective gastro-enteritis and colitis
0.605 0.395 0.000
R30 Pain associated with micturition
0.604 0.396 0.000
R36 Urethral discharge
0.604 0.396 0.000
R34 Anuria and oliguria
0.604 0.396 0.000
F32 Depressive episode
0.600 0.400 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.597 0.403 0.000
G44 Other headache syndromes
0.597 0.403 0.000
G41 Status epilepticus
0.597 0.403 0.000
C50-C50 Malignant neoplasm of breast
0.595 0.405 0.000
H35 Other retinal disorders
0.594 0.406 0.000
J33.9 Nasal polyp, unspecified
0.593 0.407 0.000
R79 Other abnormal findings of blood chemistry
0.591 0.409 0.000
H40-H42 Glaucoma
0.590 0.410 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.589 0.411 0.000
G81 Hemiplegia
0.588 0.412 0.000
R39 Other symptoms and signs involving the urinary system
0.587 0.413 0.000
R50 Fever of unknown origin
0.586 0.413 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.586 0.414 0.000
J34.3 Hypertrophy of nasal turbinates
0.586 0.414 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.586 0.414 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.586 0.414 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.584 0.416 0.000
N32.8 Other specified disorders of bladder
0.584 0.416 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.584 0.416 0.000
B25-B34 Other viral diseases
0.583 0.416 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.583 0.417 0.000
M91-M94 Chondropathies
0.583 0.417 0.000
M86-M90 Other osteopathies
0.583 0.417 0.000
M65-M68 Disorders of synovium and tendon
0.583 0.417 0.000
M60-M63 Disorders of muscles
0.583 0.417 0.000
M40-M43 Deforming dorsopathies
0.583 0.417 0.000
M00-M03 Infectious arthropathies
0.583 0.417 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.583 0.417 0.000
K08 Other disorders of teeth and supporting structures
0.582 0.418 0.000
K90-K93 Other diseases of the digestive system
0.580 0.420 0.000
N37 Urethral disorders in diseases classified elsewhere
0.579 0.421 0.000
N36 Other disorders of urethra
0.579 0.421 0.000
N34 Urethritis and urethral syndrome
0.579 0.421 0.000
N33 Bladder disorders in diseases classified elsewhere
0.579 0.421 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.579 0.421 0.000
N30 Cystitis
0.579 0.421 0.000
I34 Nonrheumatic mitral valve disorders
0.579 0.421 0.000
R53 Malaise and fatigue
0.579 0.421 0.000
R56 Convulsions, not elsewhere classified
0.579 0.421 0.000
R68 Other general symptoms and signs
0.578 0.422 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.578 0.422 0.000
R62 Lack of expected normal physiological development
0.578 0.422 0.000
R61 Hyperhidrosis
0.578 0.422 0.000
R60 Oedema, not elsewhere classified
0.578 0.422 0.000
R59 Enlarged lymph nodes
0.578 0.422 0.000
R57 Shock, not elsewhere classified
0.578 0.422 0.000
R52 Pain, not elsewhere classified
0.578 0.422 0.000
R64 Cachexia
0.578 0.422 0.000
R58 Haemorrhage, not elsewhere classified
0.578 0.422 0.000
R54 Senility
0.578 0.422 0.000
M80-M85 Disorders of bone density and structure
0.577 0.423 0.000
I05-I09 Chronic rheumatic heart diseases
0.577 0.423 0.000
I00-I02 Acute rheumatic fever
0.577 0.423 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.577 0.423 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.577 0.423 0.000
R01 Cardiac murmurs and other cardiac sounds
0.577 0.423 0.000
R02 Gangrene, not elsewhere classified
0.577 0.423 0.000
K70-K77 Diseases of liver
0.576 0.423 0.000
M45-M49 Spondylopathies
0.576 0.424 0.000
N23 Unspecified renal colic
0.575 0.425 0.000
J22 Unspecified acute lower respiratory infection
0.575 0.425 0.000
K55-K64 Other diseases of intestines
0.572 0.428 0.000
B95-B98 Bacterial, viral and other infectious agents
0.571 0.429 0.000
M25 Other joint disorders, not elsewhere classified
0.570 0.430 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.569 0.431 0.000
N21 Calculus of lower urinary tract
0.569 0.431 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.569 0.431 0.000
N41.8 Other inflammatory diseases of prostate
0.569 0.431 0.000
N41.3 Prostatocystitis
0.569 0.431 0.000
N41.2 Abscess of prostate
0.569 0.431 0.000
N41.0 Acute prostatitis
0.569 0.431 0.000
R27 Other lack of coordination
0.568 0.431 0.000
R25 Abnormal involuntary movements
0.568 0.431 0.000
R55 Syncope and collapse
0.567 0.432 0.000
A30-A49 Other bacterial diseases
0.561 0.439 0.000
D17 Benign lipomatous neoplasm
0.560 0.440 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.559 0.441 0.000
O85-O92 Complications predominantly related to the puerperium
0.559 0.441 0.000
O80-O84 Delivery
0.559 0.441 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.559 0.441 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.559 0.441 0.000
O00-O08 Pregnancy with abortive outcome
0.559 0.441 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.559 0.441 0.000
G56 Mononeuropathies of upper limb
0.558 0.442 0.000
R18 Ascites
0.558 0.442 0.000
M05-M14 Inflammatory polyarthropathies
0.557 0.443 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.557 0.443 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.557 0.443 0.000
H25 Senile cataract
0.556 0.444 0.000
R63 Symptoms and signs concerning food and fluid intake
0.555 0.445 0.000
I50 Heart failure
0.554 0.446 0.000
K65-K67 Diseases of peritoneum
0.552 0.448 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.550 0.450 0.000
C62 Malignant neoplasm of testis
0.550 0.450 0.000
C60 Malignant neoplasm of penis
0.550 0.450 0.000
B99-B99 Other infectious diseases
0.548 0.452 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.548 0.452 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.548 0.452 0.000
B65-B83 Helminthiases
0.548 0.452 0.000
B50-B64 Protozoal diseases
0.548 0.452 0.000
B35-B49 Mycoses
0.548 0.452 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.548 0.452 0.000
B15-B19 Viral hepatitis
0.548 0.452 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.548 0.452 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.548 0.452 0.000
A80-A89 Viral infections of the central nervous system
0.548 0.452 0.000
A75-A79 Rickettsioses
0.548 0.452 0.000
A70-A74 Other diseases caused by chlamydiae
0.548 0.452 0.000
A65-A69 Other spirochaetal diseases
0.548 0.452 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.548 0.452 0.000
A20-A28 Certain zoonotic bacterial diseases
0.548 0.452 0.000
A15-A19 Tuberculosis
0.548 0.452 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.548 0.452 0.000
R21 Rash and other nonspecific skin eruption
0.548 0.452 0.000
R19.4 Change in bowel habit
0.546 0.454 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.545 0.455 0.000
M20 Acquired deformities of fingers and toes
0.544 0.456 0.000
M15-M19 Arthrosis
0.544 0.456 0.000
O60-O75 Complications of labour and delivery
0.543 0.457 0.000
N39 Other disorders of urinary system
0.542 0.458 0.000
F41 Other anxiety disorders
0.542 0.458 0.000
D12.5 Sigmoid colon
0.541 0.459 0.000
I63 Cerebral infarction
0.539 0.461 0.000
J94 Other pleural conditions
0.538 0.461 0.000
J93 Pneumothorax
0.538 0.461 0.000
J92 Pleural plaque
0.538 0.461 0.000
J91 Pleural effusion in conditions classified elsewhere
0.538 0.461 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.538 0.462 0.000
R77 Other abnormalities of plasma proteins
0.538 0.462 0.000
R76 Other abnormal immunological findings in serum
0.538 0.462 0.000
R74 Abnormal serum enzyme levels
0.538 0.462 0.000
R73 Elevated blood glucose level
0.538 0.462 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.538 0.462 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.538 0.462 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.538 0.462 0.000
R71 Abnormality of red blood cells
0.538 0.462 0.000
D36 Benign neoplasm of other and unspecified sites
0.537 0.462 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.537 0.462 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.537 0.462 0.000
D32 Benign neoplasm of meninges
0.537 0.462 0.000
D31 Benign neoplasm of eye and adnexa
0.537 0.462 0.000
D30 Benign neoplasm of urinary organs
0.537 0.462 0.000
D29 Benign neoplasm of male genital organs
0.537 0.462 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.537 0.462 0.000
D26 Other benign neoplasms of uterus
0.537 0.462 0.000
D23 Other benign neoplasms of skin
0.537 0.462 0.000
D22 Melanocytic naevi
0.537 0.462 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.537 0.462 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.537 0.462 0.000
D19 Benign neoplasm of mesothelial tissue
0.537 0.462 0.000
D18 Haemangioma and lymphangioma, any site
0.537 0.462 0.000
D16 Benign neoplasm of bone and articular cartilage
0.537 0.462 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.537 0.462 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.537 0.462 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.537 0.462 0.000
D11 Benign neoplasm of major salivary glands
0.537 0.462 0.000
D10 Benign neoplasm of mouth and pharynx
0.537 0.462 0.000
D34 Benign neoplasm of thyroid gland
0.537 0.462 0.000
D27 Benign neoplasm of ovary
0.537 0.462 0.000
D24 Benign neoplasm of breast
0.537 0.462 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.535 0.465 0.000
R17 Unspecified jaundice
0.535 0.465 0.000
R14 Flatulence and related conditions
0.535 0.465 0.000
R12 Heartburn
0.535 0.465 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.534 0.466 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.533 0.467 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.531 0.469 0.000
D80-D89 Certain disorders involving the immune mechanism
0.529 0.471 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.529 0.471 0.000
D55-D59 Haemolytic anaemias
0.529 0.471 0.000
A00-A09 Intestinal infectious diseases
0.528 0.472 0.000
G47.3 Sleep apnoea
0.528 0.472 0.000
S01 Open wound of head
0.527 0.472 0.000
R13 Dysphagia
0.526 0.474 0.000
N50.8 Other specified disorders of male genital organs
0.525 0.474 0.000
I25 Chronic ischaemic heart disease
0.525 0.475 0.000
I67 Other cerebrovascular diseases
0.523 0.477 0.000
J21 Acute bronchiolitis
0.523 0.477 0.000
J20 Acute bronchitis
0.523 0.477 0.000
F32.9 Depressive episode, unspecified
0.522 0.478 0.000
G83 Other paralytic syndromes
0.521 0.478 0.000
G82 Paraplegia and tetraplegia
0.521 0.478 0.000
G80 Infantile cerebral palsy
0.521 0.478 0.000
R42 Dizziness and giddiness
0.521 0.479 0.000
R23 Other skin changes
0.520 0.480 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.520 0.480 0.000
R20 Disturbances of skin sensation
0.520 0.480 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.519 0.480 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.519 0.480 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.519 0.480 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.518 0.482 0.000
H35.8 Other specified retinal disorders
0.517 0.483 0.000
N20.1 Calculus of ureter
0.517 0.483 0.000
R69 Unknown and unspecified causes of morbidity
0.517 0.483 0.000
I51 Complications and ill-defined descriptions of heart disease
0.517 0.483 0.000
K40-K46 Hernia
0.515 0.485 0.000
N50.9 Disorder of male genital organs, unspecified
0.514 0.486 0.000
N50.1 Vascular disorders of male genital organs
0.514 0.486 0.000
N50.0 Atrophy of testis
0.514 0.486 0.000
J33.8 Other polyp of sinus
0.512 0.488 0.000
J33.1 Polypoid sinus degeneration
0.512 0.488 0.000
J33.0 Polyp of nasal cavity
0.512 0.488 0.000
H90-H95 Other disorders of ear
0.511 0.489 0.000
H80-H83 Diseases of inner ear
0.511 0.489 0.000
H65-H75 Diseases of middle ear and mastoid
0.511 0.489 0.000
H60-H62 Diseases of external ear
0.511 0.489 0.000
P90-P96 Other disorders originating in the perinatal period
0.511 0.489 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.511 0.489 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.511 0.489 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.511 0.489 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.511 0.489 0.000
P35-P39 Infections specific to the perinatal period
0.511 0.489 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.511 0.489 0.000
P10-P15 Birth trauma
0.511 0.489 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.511 0.489 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.511 0.489 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.511 0.489 0.000
Q80-Q89 Other congenital malformations
0.511 0.489 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.511 0.489 0.000
Q60-Q64 Congenital malformations of the urinary system
0.511 0.489 0.000
Q50-Q56 Congenital malformations of genital organs
0.511 0.489 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.511 0.489 0.000
Q35-Q37 Cleft lip and cleft palate
0.511 0.489 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.511 0.489 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.511 0.489 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.511 0.489 0.000
Q00-Q07 Congenital malformations of the nervous system
0.511 0.489 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.511 0.489 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.511 0.489 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.511 0.489 0.000
G58 Other mononeuropathies
0.511 0.489 0.000
G57 Mononeuropathies of lower limb
0.511 0.489 0.000
G54 Nerve root and plexus disorders
0.511 0.489 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.511 0.489 0.000
G52 Disorders of other cranial nerves
0.511 0.489 0.000
G51 Facial nerve disorders
0.511 0.489 0.000
G50 Disorders of trigeminal nerve
0.511 0.489 0.000
R04.2 Haemoptysis
0.511 0.489 0.000
I35 Nonrheumatic aortic valve disorders
0.511 0.489 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.510 0.489 0.000
T87 Complications peculiar to reattachment and amputation
0.510 0.489 0.000
T86 Failure and rejection of transplanted organs and tissues
0.510 0.489 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.510 0.489 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.510 0.489 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.510 0.489 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.510 0.489 0.000
G45.4 Transient global amnesia
0.510 0.489 0.000
G45.3 Amaurosis fugax
0.510 0.489 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.510 0.489 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.510 0.489 0.000
G45.0 Vertebro-basilar artery syndrome
0.510 0.489 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.510 0.490 0.000
D50-D53 Nutritional anaemias
0.510 0.490 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.510 0.490 0.000
R46 Symptoms and signs involving appearance and behaviour
0.509 0.491 0.000
R45 Symptoms and signs involving emotional state
0.509 0.491 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.509 0.491 0.000
R43 Disturbances of smell and taste
0.509 0.491 0.000
R40 Somnolence, stupor and coma
0.509 0.491 0.000
I47 Paroxysmal tachycardia
0.509 0.491 0.000
G40.9 Epilepsy, unspecified
0.509 0.491 0.000
D12.8 Rectum
0.509 0.491 0.000
J44 Other chronic obstructive pulmonary disease
0.509 0.491 0.000
F38 Other mood [affective] disorders
0.508 0.492 0.000
F34 Persistent mood [affective] disorders
0.508 0.492 0.000
F33 Recurrent depressive disorder
0.508 0.492 0.000
F31 Bipolar affective disorder
0.508 0.492 0.000
F30 Manic episode
0.508 0.492 0.000
F39 Unspecified mood [affective] disorder
0.508 0.492 0.000
N20.0 Calculus of kidney
0.508 0.492 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.508 0.492 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.508 0.492 0.000
N06 Isolated proteinuria with specified morphological lesion
0.508 0.492 0.000
N05 Unspecified nephritic syndrome
0.508 0.492 0.000
N04 Nephrotic syndrome
0.508 0.492 0.000
N03 Chronic nephritic syndrome
0.508 0.492 0.000
N02 Recurrent and persistent haematuria
0.508 0.492 0.000
N01 Rapidly progressive nephritic syndrome
0.508 0.492 0.000
N00 Acute nephritic syndrome
0.508 0.492 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.508 0.492 0.000
N15 Other renal tubulo-interstitial diseases
0.508 0.492 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.508 0.492 0.000
N13 Obstructive and reflux uropathy
0.508 0.492 0.000
N11 Chronic tubulo-interstitial nephritis
0.508 0.492 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.508 0.492 0.000
N10 Acute tubulo-interstitial nephritis
0.508 0.492 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.508 0.492 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.508 0.492 0.000
N27 Small kidney of unknown cause
0.508 0.492 0.000
N25 Disorders resulting from impaired renal tubular function
0.508 0.492 0.000
N26 Unspecified contracted kidney
0.508 0.492 0.000
N64 Other disorders of breast
0.508 0.492 0.000
N60 Benign mammary dysplasia
0.508 0.492 0.000
N63 Unspecified lump in breast
0.508 0.492 0.000
N62 Hypertrophy of breast
0.508 0.492 0.000
N61 Inflammatory disorders of breast
0.508 0.492 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.508 0.492 0.000
N76 Other inflammation of vagina and vulva
0.508 0.492 0.000
N75 Diseases of Bartholin's gland
0.508 0.492 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.508 0.492 0.000
N73 Other female pelvic inflammatory diseases
0.508 0.492 0.000
N71 Inflammatory disease of uterus, except cervix
0.508 0.492 0.000
N70 Salpingitis and oophoritis
0.508 0.492 0.000
N72 Inflammatory disease of cervix uteri
0.508 0.492 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.508 0.492 0.000
H52 Disorders of refraction and accommodation
0.507 0.493 0.000
N42.9 Disorder of prostate, unspecified
0.506 0.494 0.000
N42.8 Other specified disorders of prostate
0.506 0.494 0.000
N42.3 Dysplasia of prostate
0.506 0.494 0.000
N42.2 Atrophy of prostate
0.506 0.494 0.000
N42.1 Congestion and haemorrhage of prostate
0.506 0.494 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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