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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3803064
log Bayes Factor = 0.498587
Chromosome 12   position 113,173,494  (GRCh37) Explore rs3803064 on Ensembl!
Variant rs3803064 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.493 0.507
I20.9 Angina pectoris, unspecified
0.000 0.643 0.357
I20 Angina pectoris
0.000 0.674 0.326
I20-I25 Ischaemic heart diseases
0.000 0.681 0.319
I21 Acute myocardial infarction
0.000 0.698 0.302
I25 Chronic ischaemic heart disease
0.000 0.724 0.276
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.728 0.272
I20.0 Unstable angina
0.000 0.734 0.266
I22 Subsequent myocardial infarction
0.000 0.739 0.261
I25.5 Ischaemic cardiomyopathy
0.000 0.742 0.258
I10 Essential (primary) hypertension
0.000 0.742 0.258
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.749 0.251
I21.4 Acute subendocardial myocardial infarction
0.000 0.750 0.250
I10-I15 Hypertensive diseases
0.000 0.750 0.250
I25.2 Old myocardial infarction
0.000 0.756 0.244
Chapter IX Diseases of the circulatory system
0.000 0.756 0.244
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.758 0.242
I21.9 Acute myocardial infarction, unspecified
0.000 0.763 0.237
I23 Certain current complications following acute myocardial infarction
0.000 0.767 0.233
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.768 0.232
I05-I09 Chronic rheumatic heart diseases
0.000 0.769 0.231
I27 Other pulmonary heart diseases
0.000 0.771 0.229
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.775 0.225
E03 Other hypothyroidism
0.000 0.775 0.225
I12 Hypertensive renal disease
0.000 0.777 0.223
I27.0 Primary pulmonary hypertension
0.000 0.779 0.221
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.783 0.217
I05 Rheumatic mitral valve diseases
0.000 0.784 0.216
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.794 0.206
I22.8 Subsequent myocardial infarction of other sites
0.000 0.794 0.206
I12.9 Hypertensive renal disease without renal failure
0.000 0.795 0.205
I05.0 Mitral stenosis
0.000 0.800 0.200
I25.3 Aneurysm of heart
0.000 0.800 0.199
I25.6 Silent myocardial ischaemia
0.000 0.802 0.198
I27.8 Other specified pulmonary heart diseases
0.000 0.803 0.197
I25.4 Coronary artery aneurysm
0.000 0.807 0.193
I05.1 Rheumatic mitral insufficiency
0.000 0.811 0.189
I27.2 Other secondary pulmonary hypertension
0.000 0.816 0.184
I06 Rheumatic aortic valve diseases
0.000 0.820 0.180
I24 Other acute ischaemic heart diseases
0.000 0.820 0.180
I20.8 Other forms of angina pectoris
0.000 0.822 0.178
I25.1 Atherosclerotic heart disease
0.000 0.824 0.176
I13 Hypertensive heart and renal disease
0.000 0.824 0.176
I08 Multiple valve diseases
0.000 0.825 0.175
I00-I02 Acute rheumatic fever
0.000 0.826 0.174
I23.8 Other current complications following acute myocardial infarction
0.000 0.828 0.172
I09 Other rheumatic heart diseases
0.000 0.831 0.169
I07 Rheumatic tricuspid valve diseases
0.000 0.832 0.168
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.833 0.167
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.833 0.167
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.833 0.167
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.833 0.167
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.833 0.167
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.833 0.167
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.833 0.167
E03.8 Other specified hypothyroidism
0.000 0.833 0.167
I05.2 Mitral stenosis with insufficiency
0.000 0.833 0.167
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.833 0.166
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.834 0.166
I27.1 Kyphoscoliotic heart disease
0.000 0.835 0.164
I28 Other diseases of pulmonary vessels
0.000 0.836 0.164
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.837 0.163
I11 Hypertensive heart disease
0.000 0.838 0.162
E03.5 Myxoedema coma
0.000 0.839 0.161
E03.4 Atrophy of thyroid (acquired)
0.000 0.839 0.161
E03.3 Postinfectious hypothyroidism
0.000 0.839 0.161
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.841 0.159
E03.1 Congenital hypothyroidism without goitre
0.000 0.843 0.157
I12.0 Hypertensive renal disease with renal failure
0.000 0.845 0.155
I05.8 Other mitral valve diseases
0.000 0.845 0.155
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.847 0.153
I27.9 Pulmonary heart disease, unspecified
0.000 0.847 0.153
I08.9 Multiple valve disease, unspecified
0.000 0.852 0.148
I08.0 Disorders of both mitral and aortic valves
0.000 0.855 0.145
I24.1 Dressler's syndrome
0.000 0.856 0.144
I24.8 Other forms of acute ischaemic heart disease
0.000 0.858 0.142
I06.0 Rheumatic aortic stenosis
0.000 0.860 0.140
I06.1 Rheumatic aortic insufficiency
0.000 0.863 0.137
I15 Secondary hypertension
0.000 0.870 0.130
I06.8 Other rheumatic aortic valve diseases
0.000 0.871 0.129
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.871 0.129
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.873 0.127
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.874 0.126
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.874 0.126
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.874 0.126
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.874 0.126
I09.9 Rheumatic heart disease, unspecified
0.000 0.875 0.125
I02 Rheumatic chorea
0.000 0.875 0.125
I01 Rheumatic fever with heart involvement
0.000 0.875 0.125
I00 Rheumatic fever without mention of heart involvement
0.000 0.876 0.124
I26 Pulmonary embolism
0.000 0.876 0.124
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.877 0.122
I07.1 Tricuspid insufficiency
0.000 0.878 0.122
I09.8 Other specified rheumatic heart diseases
0.000 0.878 0.122
I09.2 Chronic rheumatic pericarditis
0.000 0.878 0.122
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.878 0.122
I09.0 Rheumatic myocarditis
0.000 0.878 0.122
I07.9 Tricuspid valve disease, unspecified
0.000 0.880 0.120
I07.8 Other tricuspid valve diseases
0.000 0.880 0.120
I07.2 Tricuspid stenosis with insufficiency
0.000 0.880 0.120
I07.0 Tricuspid stenosis
0.000 0.880 0.120
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.882 0.118
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.882 0.117
I28.1 Aneurysm of pulmonary artery
0.000 0.882 0.117
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.882 0.117
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.882 0.117
I28.8 Other specified diseases of pulmonary vessels
0.000 0.886 0.114
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.888 0.112
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.896 0.104
I15.0 Renovascular hypertension
0.000 0.899 0.101
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.900 0.100
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.900 0.100
I20.1 Angina pectoris with documented spasm
0.000 0.902 0.097
I05.9 Mitral valve disease, unspecified
0.000 0.905 0.095
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.906 0.094
I15.8 Other secondary hypertension
0.000 0.907 0.093
I15.9 Seconday hypertension, unspecified
0.000 0.907 0.093
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.910 0.090
I01.8 Other acute rheumatic heart disease
0.000 0.910 0.090
I01.2 Acute rheumatic myocarditis
0.000 0.910 0.090
I01.1 Acute rheumatic endocarditis
0.000 0.910 0.090
I01.0 Acute rheumatic pericarditis
0.000 0.910 0.090
I02.9 Rheumatic chorea without heart involvement
0.000 0.910 0.090
I02.0 Rheumatic chorea with heart involvement
0.000 0.910 0.090
E00-E07 Disorders of thyroid gland
0.000 0.911 0.089
E06.3 Autoimmune thyroiditis
0.000 0.913 0.087
E06 Thyroiditis
0.000 0.913 0.087
I08.8 Other multiple valve diseases
0.000 0.915 0.085
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.919 0.081
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.920 0.080
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.924 0.076
E10.1 With ketoacidosis
0.000 0.924 0.076
E10 Insulin-dependent diabetes mellitus
0.000 0.925 0.075
I15.2 Hypertension secondary to endocrine disorders
0.000 0.925 0.075
E10.9 Without complications
0.000 0.931 0.069
E06.5 Other chronic thyroiditis
0.000 0.933 0.067
E10.5 With peripheral circulatory complications
0.000 0.934 0.066
E10.3 With ophthalmic complications
0.000 0.934 0.066
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.936 0.064
E00 Congenital iodine-deficiency syndrome
0.000 0.936 0.064
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.936 0.064
E06.4 Drug-induced thyroiditis
0.000 0.937 0.063
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.937 0.063
E06.1 Subacute thyroiditis
0.000 0.937 0.063
E06.0 Acute thyroiditis
0.000 0.937 0.063
E10.2 With renal complications
0.000 0.938 0.062
E10.4 With neurological complications
0.000 0.940 0.060
I15.1 Hypertension secondary to other renal disorders
0.000 0.940 0.059
E10.6 With other specified complications
0.000 0.941 0.059
E10.0 With coma
0.000 0.942 0.058
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.942 0.058
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.942 0.058
I97.0 Postcardiotomy syndrome
0.000 0.942 0.058
E06.9 Thyroiditis, unspecified
0.000 0.943 0.057
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.947 0.053
I99 Other and unspecified disorders of circulatory system
0.000 0.947 0.053
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.949 0.051
E10.7 With multiple complications
0.000 0.950 0.049
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.951 0.049
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.951 0.049
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.954 0.046
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.954 0.046
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.954 0.046
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.954 0.046
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.954 0.046
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.954 0.046
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.954 0.046
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.954 0.046
E10.8 With unspecified complications
0.000 0.957 0.043
E05.8 Other thyrotoxicosis
0.000 0.959 0.041
E07 Other disorders of thyroid
0.000 0.960 0.039
I97.1 Other functional disturbances following cardiac surgery
0.000 0.961 0.039
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.963 0.037
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.963 0.036
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.963 0.036
I98.0 Cardiovascular syphilis
0.000 0.963 0.036
E05.9 Thyrotoxicosis, unspecified
0.000 0.964 0.036
E05.5 Thyroid crisis or storm
0.000 0.965 0.035
E05.4 Thyrotoxicosis factitia
0.000 0.965 0.035
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.965 0.035
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.965 0.035
E10-E14 Diabetes mellitus
0.000 0.966 0.034
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.967 0.033
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.968 0.032
E07.1 Dyshormogenetic goitre
0.000 0.971 0.028
E07.0 Hypersecretion of calcitonin
0.000 0.971 0.028
E13 Other specified diabetes mellitus
0.000 0.975 0.025
E12 Malnutrition-related diabetes mellitus
0.000 0.975 0.024
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.976 0.024
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.976 0.024
E07.8 Other specified disorders of thyroid
0.000 0.977 0.023
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.977 0.023
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.978 0.022
M81.98 Osteoporosis, unspecified (Other)
0.022 0.978 0.000
C67.5 Bladder neck
0.000 0.979 0.021
Z82.3 Family history of stroke
0.000 0.980 0.020
C67 Malignant neoplasm of bladder
0.000 0.980 0.020
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.980 0.020
E13.3 With ophthalmic complications
0.000 0.980 0.020
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.980 0.020
C67.1 Dome of bladder
0.000 0.981 0.019
C67.4 Posterior wall of bladder
0.000 0.981 0.019
E13.8 With unspecified complications
0.000 0.982 0.018
E13.7 With multiple complications
0.000 0.982 0.018
E13.6 With other specified complications
0.000 0.982 0.018
E13.5 With peripheral circulatory complications
0.000 0.982 0.018
E13.4 With neurological complications
0.000 0.982 0.018
E13.2 With renal complications
0.000 0.982 0.018
E13.1 With ketoacidosis
0.000 0.982 0.018
E13.0 With coma
0.000 0.982 0.018
E12.9 Without complications
0.000 0.982 0.018
E12.8 With unspecified complications
0.000 0.982 0.018
E12.7 With multiple complications
0.000 0.982 0.018
E12.6 With other specified complications
0.000 0.982 0.018
E12.5 With peripheral circulatory complications
0.000 0.982 0.018
E12.4 With neurological complications
0.000 0.982 0.018
E12.3 With ophthalmic complications
0.000 0.982 0.018
E12.2 With renal complications
0.000 0.982 0.018
E12.1 With ketoacidosis
0.000 0.982 0.018
E12.0 With coma
0.000 0.982 0.018
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.982 0.018
Z82.2 Family history of deafness and hearing loss
0.000 0.982 0.018
E14 Unspecified diabetes mellitus
0.000 0.983 0.017
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.983 0.017
C67.6 Ureteric orifice
0.000 0.983 0.017
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.983 0.017
E40-E46 Malnutrition
0.000 0.984 0.016
E13.9 Without complications
0.000 0.984 0.016
C67.8 Overlapping lesion of bladder
0.000 0.984 0.016
C67.2 Lateral wall of bladder
0.000 0.984 0.016
C67.0 Trigone of bladder
0.000 0.984 0.016
E11 Non-insulin-dependent diabetes mellitus
0.000 0.984 0.016
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.985 0.015
E07.9 Disorder of thyroid, unspecified
0.000 0.985 0.015
D35.0 Adrenal gland
0.015 0.985 0.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.985 0.015
C67.7 Urachus
0.000 0.985 0.015
E11.4 With neurological complications
0.000 0.985 0.015
E14.8 With unspecified complications
0.000 0.986 0.014
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.986 0.014
Z82.1 Family history of blindness and visual loss
0.000 0.986 0.014
C44.1 Skin of eyelid, including canthus
0.000 0.986 0.014
E14.6 With other specified complications
0.000 0.986 0.014
E11.1 With ketoacidosis
0.000 0.986 0.014
C67.3 Anterior wall of bladder
0.000 0.987 0.013
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.987 0.013
I95 Hypotension
0.000 0.987 0.013
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.987 0.013
E14.4 With neurological complications
0.000 0.987 0.013
E14.2 Withrenal complications
0.000 0.987 0.013
E14.1 With ketoacidosis
0.000 0.987 0.013
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.987 0.013
E14.7 With multiple complications
0.000 0.987 0.013
E14.0 With coma
0.000 0.987 0.013
E11.3 With ophthalmic complications
0.000 0.987 0.013
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.987 0.013
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.988 0.012
E15 Nondiabetic hypoglycaemic coma
0.000 0.988 0.012
T81.4 Infection following a procedure, not elsewhere classified
0.000 0.988 0.012
D35.1 Parathyroid gland
0.012 0.988 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.988 0.012
E45 Retarded development following protein-energy malnutrition
0.000 0.988 0.012
E43 Unspecified severe protein-energy malnutrition
0.000 0.988 0.012
E42 Marasmic kwashiorkor
0.000 0.988 0.012
E41 Nutritional marasmus
0.000 0.988 0.012
E40 Kwashiorkor
0.000 0.988 0.012
D35 Benign neoplasm of other and unspecified endocrine glands
0.012 0.988 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.989 0.011
E11.2 With renal complications
0.000 0.989 0.011
I95.8 Other hypotension
0.000 0.989 0.011
D68.9 Coagulation defect, unspecified
0.000 0.989 0.011
E16 Other disorders of pancreatic internal secretion
0.000 0.989 0.011
E14.3 With ophthalmic complications
0.000 0.989 0.011
D68 Other coagulation defects
0.000 0.989 0.011
E11.7 With multiple complications
0.000 0.989 0.011
E14.5 With peripheral circulatory complications
0.000 0.989 0.011
D68.8 Other specified coagulation defects
0.000 0.989 0.011
D68.6 Other Thrombophilia
0.000 0.989 0.011
E11.6 With other specified complications
0.000 0.989 0.011
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.990 0.010
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.990 0.010
E46 Unspecified protein-energy malnutrition
0.000 0.990 0.010
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.990 0.010
D68.2 Hereditary deficiency of other clotting factors
0.000 0.990 0.010
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.990 0.010
E11.0 With coma
0.000 0.990 0.010
E11.8 With unspecified complications
0.000 0.990 0.009
C67.9 Bladder, unspecified
0.000 0.991 0.009
D35.9 Endocrine gland, unspecified
0.009 0.991 0.000
D35.8 Pluriglandular involvement
0.009 0.991 0.000
D35.7 Other specified endocrine glands
0.009 0.991 0.000
D35.6 Aortic body and other paraganglia
0.009 0.991 0.000
D35.5 Carotid body
0.009 0.991 0.000
D35.4 Pineal gland
0.009 0.991 0.000
D35.3 Craniopharyngeal duct
0.009 0.991 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.991 0.009
E44.0 Moderate protein-energy malnutrition
0.000 0.991 0.009
I95.0 Idiopathic hypotension
0.000 0.991 0.009
C64-C68 Malignant neoplasms of urinary tract
0.000 0.991 0.009
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.991 0.008
D35.2 Pituitary gland
0.009 0.991 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.992 0.008
M81.9 Osteoporosis, unspecified
0.008 0.992 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.992 0.008
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.992 0.008
E16.4 Abnormal secretion of gastrin
0.000 0.992 0.008
E16.3 Increased secretion of glucagon
0.000 0.992 0.008
D68.0 Von Willebrand's disease
0.000 0.992 0.008
C66 Malignant neoplasm of ureter
0.000 0.992 0.008
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.000 0.992 0.008
C65 Malignant neoplasm of renal pelvis
0.000 0.992 0.008
M81.96 Osteoporosis, unspecified (Lower leg)
0.008 0.992 0.000
H57.1 Ocular pain
0.000 0.992 0.008
D68.1 Hereditary factor XI deficiency
0.000 0.992 0.007
R22.4 Localised swelling, mass and lump, lower limb
0.007 0.993 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.007 0.993 0.000
D68.4 Acquired coagulation factor deficiency
0.000 0.993 0.007
E50-E64 Other nutritional deficiencies
0.000 0.993 0.007
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.993 0.007
E65-E68 Obesity and other hyperalimentation
0.000 0.993 0.007
H83.0 Labyrinthitis
0.007 0.993 0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified
0.000 0.993 0.007
R16.1 Splenomegaly, not elsewhere classified
0.000 0.993 0.007
M81.93 Osteoporosis, unspecified (Forearm)
0.007 0.993 0.000
D68.5 Primary Thrombophilia
0.000 0.993 0.007
M81.92 Osteoporosis, unspecified (Upper arm)
0.006 0.994 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.006 0.994 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.000 0.994 0.006
E04 Other non-toxic goitre
0.000 0.994 0.006
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.006 0.994 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.994 0.006
E16.1 Other hypoglycaemia
0.000 0.994 0.005
C68 Malignant neoplasm of other and unspecified urinary organs
0.000 0.994 0.006
M06 Other rheumatoid arthritis
0.000 0.994 0.006
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.000 0.994 0.006
T82.0 Mechanical complication of heart valve prosthesis
0.000 0.994 0.006
E61 Deficiency of other nutrient elements
0.000 0.994 0.005
R16.0 Hepatomegaly, not elsewhere classified
0.000 0.995 0.005
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.995 0.005
E50 Vitamin A deficiency
0.000 0.995 0.005
E60 Dietary zinc deficiency
0.000 0.995 0.005
E59 Dietary selenium deficiency
0.000 0.995 0.005
E52 Niacin deficiency [pellagra]
0.000 0.995 0.005
E67 Other hyperalimentation
0.000 0.995 0.005
E68 Sequelae of hyperalimentation
0.000 0.995 0.005
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.995 0.005
E51 Thiamine deficiency
0.000 0.995 0.005
I95.2 Hypotension due to drugs
0.000 0.995 0.005
E63 Other nutritional deficiencies
0.000 0.995 0.005
T82.3 Mechanical complication of other vascular grafts
0.000 0.995 0.005
E58 Dietary calcium deficiency
0.000 0.995 0.005
D22.5 Melanocytic naevi of trunk
0.000 0.995 0.005
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.000 0.995 0.005
K66.8 Other specified disorders of peritoneum
0.000 0.995 0.005
S02.80 Fractures of other skull and facial bones (closed)
0.005 0.995 0.000
E56 Other vitamin deficiencies
0.000 0.995 0.005
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.000 0.995 0.005
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.005 0.995 0.000
I77.6 Arteritis, unspecified
0.000 0.995 0.005
M81 Osteoporosis without pathological fracture
0.005 0.995 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.995 0.005
E04.8 Other specified non-toxic goitre
0.000 0.995 0.004
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.995 0.005
M06.3 Rheumatoid nodule
0.000 0.995 0.005
S02.40 Fracture of malar and maxillary bones (closed)
0.005 0.995 0.000
M06.8 Other specified rheumatoid arthritis
0.000 0.995 0.004
I72.3 Aneurysm of iliac artery
0.000 0.995 0.004
I85.0 Oesophageal varices with bleeding
0.000 0.995 0.004
E55 Vitamin D deficiency
0.000 0.996 0.004
C68.8 Overlapping lesion of urinary organs
0.000 0.996 0.004
C68.1 Paraurethral glands
0.000 0.996 0.004
E61.1 Iron deficiency
0.000 0.996 0.004
M06.2 Rheumatoid bursitis
0.000 0.996 0.004
N48.6 Balanitis xerotica obliterans
0.000 0.996 0.004
R81 Glycosuria
0.000 0.996 0.004
M06.4 Inflammatory polyarthropathy
0.000 0.996 0.004
I72 Other aneurysm
0.000 0.996 0.004
C68.9 Urinary organ, unspecified
0.000 0.996 0.004
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.000 0.996 0.004
I77 Other disorders of arteries and arterioles
0.000 0.996 0.004
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.996 0.004
M81.90 Osteoporosis, unspecified (Multiple sites)
0.004 0.996 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.996 0.004
E61.8 Deficiency of other specified nutrient elements
0.000 0.996 0.004
E61.7 Deficiency of multiple nutrient elements
0.000 0.996 0.004
E61.6 Vanadium deficiency
0.000 0.996 0.004
E61.5 Molybdenum deficiency
0.000 0.996 0.004
E61.4 Chromium deficiency
0.000 0.996 0.004
E61.3 Manganese deficiency
0.000 0.996 0.004
E61.0 Copper deficiency
0.000 0.996 0.004
S02.8 Fractures of other skull and facial bones
0.004 0.996 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.000 0.996 0.004
E11.5 With peripheral circulatory complications
0.000 0.996 0.004
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.000 0.996 0.004
E54 Ascorbic acid deficiency
0.000 0.996 0.004
M06.1 Adult-onset Still's disease
0.000 0.996 0.004
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.000 0.996 0.004
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.996 0.004
E50.9 Vitamin A deficiency, unspecified
0.000 0.996 0.004
E50.8 Other manifestations of vitamin A deficiency
0.000 0.996 0.004
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.996 0.004
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.996 0.004
E50.5 Vitamin A deficiency with night blindness
0.000 0.996 0.004
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.996 0.004
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.996 0.004
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.996 0.004
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.996 0.004
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.996 0.004
E61.2 Magnesium deficiency
0.000 0.996 0.004
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.996 0.004
E64.8 Sequelae of other nutritional deficiencies
0.000 0.996 0.004
E64.3 Sequelae of rickets
0.000 0.996 0.004
E64.2 Sequelae of vitamin C deficiency
0.000 0.996 0.004
E64.1 Sequelae of vitamin A deficiency
0.000 0.996 0.004
E64.0 Sequelae of protein-energy malnutrition
0.000 0.996 0.004
I79.1 Aortitis in diseases classified elsewhere
0.000 0.996 0.004
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.996 0.004
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.996 0.004
E67.8 Other specified hyperalimentation
0.000 0.996 0.004
E67.3 Hypervitaminosis D
0.000 0.996 0.004
E67.2 Megavitamin-B6 syndrome
0.000 0.996 0.004
E67.1 Hypercarotenaemia
0.000 0.996 0.004
E67.0 Hypervitaminosis A
0.000 0.996 0.004
E51.9 Thiamine deficiency, unspecified
0.000 0.996 0.004
E51.8 Other manifestations of thiamine deficiency
0.000 0.996 0.004
E51.1 Beriberi
0.000 0.996 0.004
L85.9 Epidermal thickening, unspecified
0.000 0.996 0.004
E51.2 Wernicke's encephalopathy
0.000 0.996 0.004
T82.1 Mechanical complication of cardiac electronic device
0.000 0.996 0.004
Y40.9 Systemic antibiotic, unspecified
0.000 0.996 0.004
R74.8 Abnormal levels of other serum enzymes
0.000 0.996 0.004
S12.20 Fracture of other specified cervical vertebra (closed)
0.000 0.996 0.004
E63.8 Other specified nutritional deficiencies
0.000 0.996 0.004
E63.1 Imbalance of constituents of food intake
0.000 0.996 0.004
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.996 0.004
S02.4 Fracture of malar and maxillary bones
0.004 0.996 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.996 0.004
M81.4 Drug-induced osteoporosis
0.004 0.996 0.000
S02.60 Fracture of mandible (closed)
0.004 0.996 0.000
S82.10 Fracture of upper end of tibia (closed)
0.004 0.996 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.996 0.004
E56.8 Deficiency of other vitamins
0.000 0.996 0.004
E56.0 Deficiency of vitamin E
0.000 0.996 0.004
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.000 0.996 0.004
I85 Oesophageal varices
0.000 0.996 0.004
E63.9 Nutritional deficiency, unspecified
0.000 0.996 0.003
C68.0 Urethra
0.000 0.996 0.003
M81.40 Drug-induced osteoporosis (Multiple sites)
0.004 0.996 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.004 0.996 0.000
S02.6 Fracture of mandible
0.004 0.996 0.000
M81.6 Localised osteoporosis [Lequesne]
0.004 0.996 0.000
M81.5 Idiopathic osteoporosis
0.004 0.996 0.000
M81.1 Postoophorectomy osteoporosis
0.004 0.996 0.000
I70 Atherosclerosis
0.000 0.996 0.004
M81.8 Other osteoporosis
0.004 0.996 0.000
F45.8 Other somatoform disorders
0.004 0.996 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.000 0.996 0.004
D17.9 Benign lipomatous neoplasm, unspecified
0.000 0.996 0.004
H18.9 Disorder of cornea, unspecified
0.000 0.996 0.004
S02 Fracture of skull and facial bones
0.004 0.996 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.996 0.003
I78 Diseases of capillaries
0.000 0.996 0.004
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.996 0.003
I72.9 Aneurysm of unspecified site
0.000 0.996 0.003
S93.1 Dislocation of toe(s)
0.004 0.996 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.996 0.003
M06.38 Rheumatoid nodule (Other)
0.000 0.996 0.003
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.996 0.003
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.996 0.003
M06.33 Rheumatoid nodule (Forearm)
0.000 0.996 0.003
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.996 0.003
M81.0 Postmenopausal osteoporosis
0.003 0.996 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.996 0.003
R82.8 Abnormal findings on cytological and histological examination of urine
0.000 0.996 0.004
G40.9 Epilepsy, unspecified
0.000 0.996 0.004
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.996 0.003
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.996 0.003
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.996 0.003
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.996 0.003
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.996 0.003
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.996 0.003
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.996 0.003
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.996 0.003
E56.1 Deficiency of vitamin K
0.000 0.996 0.003
M81.2 Osteoporosis of disuse
0.003 0.996 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.997 0.003
E55.0 Rickets, active
0.000 0.997 0.003
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.997 0.003
M06.28 Rheumatoid bursitis (Other)
0.000 0.997 0.003
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.997 0.003
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.997 0.003
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.997 0.003
M06.24 Rheumatoid bursitis (Hand)
0.000 0.997 0.003
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.997 0.003
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.997 0.003
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.997 0.003
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.997 0.003
M13.97 Arthritis, unspecified (Ankle and foot)
0.003 0.997 0.000
M06.0 Seronegative rheumatoid arthritis
0.000 0.997 0.003
I77.0 Arteriovenous fistula, acquired
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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