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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3969860
log Bayes Factor = 18.4227
Chromosome 19   position 11,447,886  (GRCh37) Explore rs3969860 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
R50-R69 General symptoms and signs
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.999 0.001 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.999 0.001 0.000
I95 Hypotension
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.993 0.007 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.990 0.010 0.000
Chapter XI Diseases of the digestive system
0.989 0.011 0.000
G40-G47 Episodic and paroxysmal disorders
0.987 0.013 0.000
R53 Malaise and fatigue
0.987 0.013 0.000
I95.9 Hypotension, unspecified
0.984 0.016 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.980 0.020 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.980 0.020 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.976 0.024 0.000
G90-G99 Other disorders of the nervous system
0.975 0.025 0.000
I60-I69 Cerebrovascular diseases
0.971 0.029 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.970 0.030 0.000
R55 Syncope and collapse
0.969 0.031 0.000
S00-S09 Injuries to the head
0.968 0.032 0.000
K02 Dental caries
0.966 0.034 0.000
K01 Embedded and impacted teeth
0.964 0.036 0.000
Z01.8 Other specified special examinations
0.963 0.037 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.962 0.038 0.000
G62 Other polyneuropathies
0.960 0.040 0.000
K50-K52 Noninfective enteritis and colitis
0.951 0.049 0.000
K02.9 Dental caries, unspecified
0.950 0.050 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.947 0.053 0.000
Chapter XX External causes of morbidity and mortality
0.947 0.053 0.000
Z03.4 Observation for suspected myocardial infarction
0.945 0.055 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.944 0.056 0.000
G62.9 Polyneuropathy, unspecified
0.944 0.056 0.000
I95.1 Orthostatic hypotension
0.944 0.056 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.942 0.058 0.000
K01.1 Impacted teeth
0.938 0.062 0.000
R50 Fever of unknown origin
0.938 0.062 0.000
G43 Migraine
0.935 0.065 0.000
R60 Oedema, not elsewhere classified
0.930 0.070 0.000
K52 Other non-infective gastro-enteritis and colitis
0.929 0.071 0.000
I35 Nonrheumatic aortic valve disorders
0.928 0.072 0.000
Chapter XXII Codes for special purposes
0.927 0.073 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.923 0.077 0.000
R41.0 Disorientation, unspecified
0.923 0.077 0.000
G40 Epilepsy
0.922 0.078 0.000
K04 Diseases of pulp and periapical tissues
0.921 0.079 0.000
S40-S49 Injuries to the shoulder and upper arm
0.919 0.081 0.000
R50.9 Fever, unspecified
0.919 0.081 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.916 0.084 0.000
S00 Superficial injury of head
0.914 0.086 0.000
Chapter V Mental and behavioural disorders
0.912 0.088 0.000
I51 Complications and ill-defined descriptions of heart disease
0.912 0.088 0.000
Q21 Congenital malformations of cardiac septa
0.910 0.090 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.909 0.091 0.000
R56 Convulsions, not elsewhere classified
0.908 0.092 0.000
I33 Acute and subacute endocarditis
0.907 0.093 0.000
I10-I15 Hypertensive diseases
0.905 0.095 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.903 0.097 0.000
S20-S29 Injuries to the thorax
0.902 0.098 0.000
W00-W19 Falls
0.902 0.098 0.000
G91 Hydrocephalus
0.901 0.099 0.000
S06 Intracranial injury
0.900 0.100 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.899 0.101 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.898 0.102 0.000
G43.9 Migraine, unspecified
0.893 0.107 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.893 0.107 0.000
I51.7 Cardiomegaly
0.892 0.108 0.000
R45 Symptoms and signs involving emotional state
0.891 0.109 0.000
R60.0 Localised oedema
0.887 0.113 0.000
I12 Hypertensive renal disease
0.887 0.113 0.000
I35.1 Aortic (valve) insufficiency
0.887 0.113 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.885 0.115 0.000
Z42 Follow-up care involving plastic surgery
0.883 0.117 0.000
S10-S19 Injuries to the neck
0.882 0.118 0.000
Z01.9 Special examination, unspecified
0.881 0.119 0.000
Q21.1 Atrial septal defect
0.880 0.120 0.000
I31 Other diseases of pericardium
0.879 0.121 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.876 0.124 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.875 0.125 0.000
S80-S89 Injuries to the knee and lower leg
0.872 0.128 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.872 0.128 0.000
R59 Enlarged lymph nodes
0.868 0.132 0.000
F30-F39 Mood [affective] disorders
0.867 0.133 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.866 0.134 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.865 0.135 0.000
K04.7 Periapical abscess without sinus
0.863 0.137 0.000
I38 Endocarditis, valve unspecified
0.861 0.139 0.000
L57.0 Actinic keratosis
0.860 0.140 0.000
S00.0 Superficial injury of scalp
0.859 0.141 0.000
I12.0 Hypertensive renal disease with renal failure
0.859 0.141 0.000
G20-G26 Extrapyramidal and movement disorders
0.858 0.142 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.857 0.143 0.000
R47-R49 Symptoms and signs involving speech and voice
0.852 0.148 0.000
K11 Diseases of salivary glands
0.848 0.152 0.000
Z03.1 Observation for suspected malignant neoplasm
0.846 0.154 0.000
R69 Unknown and unspecified causes of morbidity
0.845 0.155 0.000
I95.0 Idiopathic hypotension
0.845 0.155 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.844 0.156 0.000
G91.9 Hydrocephalus, unspecified
0.843 0.157 0.000
I33.0 Acute and subacute infective endocarditis
0.843 0.157 0.000
R56.8 Other and unspecified convulsions
0.842 0.158 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.839 0.161 0.000
K09 Cysts of oral region, not elsewhere classified
0.838 0.162 0.000
Z01.4 Gynaecological examination (general)(routine)
0.838 0.162 0.000
K07 Dentofacial anomalies [including malocclusion]
0.833 0.167 0.000
Z12 Special screening examination for neoplasms
0.833 0.167 0.000
S32 Fracture of lumbar spine and pelvis
0.831 0.169 0.000
R63 Symptoms and signs concerning food and fluid intake
0.830 0.170 0.000
K65-K67 Diseases of peritoneum
0.830 0.170 0.000
I46 Cardiac arrest
0.829 0.171 0.000
F33 Recurrent depressive disorder
0.829 0.171 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.827 0.173 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.824 0.176 0.000
T79-T79 Certain early complications of trauma
0.822 0.178 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.822 0.178 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.821 0.179 0.000
L50-L54 Urticaria and erythema
0.821 0.179 0.000
I67 Other cerebrovascular diseases
0.820 0.180 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.817 0.183 0.000
G40.9 Epilepsy, unspecified
0.816 0.184 0.000
Z47 Other orthopaedic follow-up care
0.816 0.184 0.000
G61 Inflammatory polyneuropathy
0.816 0.184 0.000
K05 Gingivitis and periodontal diseases
0.812 0.188 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.810 0.190 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.809 0.191 0.000
R68 Other general symptoms and signs
0.807 0.193 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.806 0.194 0.000
Z29 Need for other prophylactic measures
0.806 0.194 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.804 0.196 0.000
I95.2 Hypotension due to drugs
0.803 0.197 0.000
Q23 Congenital malformations of aortic and mitral valves
0.800 0.200 0.000
R45.1 Restlessness and agitation
0.799 0.201 0.000
Z49 Care involving dialysis
0.798 0.202 0.000
I95.8 Other hypotension
0.796 0.204 0.000
R40 Somnolence, stupor and coma
0.796 0.204 0.000
T66-T78 Other and unspecified effects of external causes
0.796 0.204 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.795 0.205 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.795 0.205 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.794 0.206 0.000
I63 Cerebral infarction
0.793 0.207 0.000
T91 Sequelae of injuries of neck and trunk
0.792 0.208 0.000
I62 Other nontraumatic intracranial haemorrhage
0.791 0.209 0.000
G41 Status epilepticus
0.791 0.209 0.000
G95 Other diseases of spinal cord
0.791 0.209 0.000
S05 Injury of eye and orbit
0.788 0.212 0.000
F33.9 Recurrent depressive disorder, unspecified
0.788 0.212 0.000
I30 Acute pericarditis
0.788 0.212 0.000
I31.3 Pericardial effusion (noninflammatory)
0.786 0.214 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.786 0.214 0.000
U89 Agent resistant to other and unspecified antibiotics
0.786 0.214 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.783 0.217 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.782 0.218 0.000
G90 Disorders of autonomic nervous system
0.782 0.218 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.781 0.219 0.000
R49 Voice disturbances
0.779 0.221 0.000
I45 Other conduction disorders
0.776 0.224 0.000
I60 Subarachnoid haemorrhage
0.775 0.225 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.773 0.227 0.000
I12.9 Hypertensive renal disease without renal failure
0.772 0.228 0.000
R52 Pain, not elsewhere classified
0.771 0.229 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.769 0.231 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.769 0.231 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.767 0.233 0.000
R41.3 Other amnesia
0.767 0.233 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.766 0.234 0.000
L90 Atrophic disorders of skin
0.765 0.235 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.765 0.235 0.000
R25 Abnormal involuntary movements
0.765 0.235 0.000
S20 Superficial injury of thorax
0.764 0.236 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.764 0.236 0.000
K55-K64 Other diseases of intestines
0.764 0.236 0.000
K01.0 Embedded teeth
0.763 0.237 0.000
S06.8 Other intracranial injuries
0.763 0.237 0.000
I47 Paroxysmal tachycardia
0.762 0.238 0.000
S50-S59 Injuries to the elbow and forearm
0.761 0.239 0.000
R79 Other abnormal findings of blood chemistry
0.761 0.239 0.000
S00.1 Contusion of eyelid and periocular area
0.761 0.239 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.760 0.240 0.000
K50 Crohn's disease [regional enteritis]
0.760 0.240 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.760 0.240 0.000
R20 Disturbances of skin sensation
0.759 0.241 0.000
W18 Other fall on same level
0.759 0.241 0.000
R61 Hyperhidrosis
0.755 0.245 0.000
I36 Nonrheumatic tricuspid valve disorders
0.754 0.246 0.000
S81 Open wound of lower leg
0.752 0.248 0.000
K07.3 Anomalies of tooth position
0.752 0.248 0.000
G30-G32 Other degenerative diseases of the nervous system
0.751 0.249 0.000
G96 Other disorders of central nervous system
0.751 0.249 0.000
R59.0 Localised enlarged lymph nodes
0.751 0.249 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.750 0.250 0.000
W19 Unspecified fall
0.749 0.251 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.749 0.251 0.000
I67.8 Other specified cerebrovascular diseases
0.747 0.253 0.000
Z03.3 Observation for suspected nervous system disorder
0.746 0.254 0.000
Y84.8 Other medical procedures
0.745 0.255 0.000
L20-L30 Dermatitis and eczema
0.745 0.255 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.744 0.256 0.000
Z40 Prophylactic surgery
0.742 0.258 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.741 0.259 0.000
S90-S99 Injuries to the ankle and foot
0.741 0.259 0.000
I99 Other and unspecified disorders of circulatory system
0.740 0.259 0.000
S40 Superficial injury of shoulder and upper arm
0.740 0.259 0.000
Q80-Q89 Other congenital malformations
0.739 0.260 0.000
Z54 Convalescence
0.739 0.260 0.000
S42 Fracture of shoulder and upper arm
0.739 0.261 0.000
G93 Other disorders of brain
0.736 0.264 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.735 0.265 0.000
I61 Intracerebral haemorrhage
0.734 0.265 0.000
S80 Superficial injury of lower leg
0.735 0.265 0.000
G25 Other extrapyramidal and movement disorders
0.734 0.266 0.000
K00 Disorders of tooth development and eruption
0.733 0.267 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.732 0.267 0.000
L90.5 Scar conditions and fibrosis of skin
0.732 0.268 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.732 0.268 0.000
I46.9 Cardiac arrest, unspecified
0.731 0.269 0.000
K62 Other diseases of anus and rectum
0.730 0.270 0.000
K09.0 Developmental odontogenic cysts
0.729 0.270 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.729 0.270 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.729 0.270 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.729 0.271 0.000
U89.8 Agent resistant to other single specified antibiotic
0.729 0.271 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.729 0.271 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.728 0.272 0.000
U88 Agent resistant to multiple antibiotics
0.728 0.272 0.000
S06.2 Diffuse brain injury
0.727 0.273 0.000
S32.0 Fracture of lumbar vertebra
0.726 0.274 0.000
G70-G73 Diseases of myoneural junction and muscle
0.726 0.274 0.000
Z29.2 Other prophylactic chemotherapy
0.726 0.274 0.000
S70-S79 Injuries to the hip and thigh
0.724 0.276 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.724 0.276 0.000
R49.0 Dysphonia
0.723 0.277 0.000
Z22 Carrier of infectious disease
0.721 0.279 0.000
W05 Fall involving wheelchair
0.721 0.279 0.000
I37 Pulmonary valve disorders
0.720 0.280 0.000
R20.2 Paraesthesia of skin
0.719 0.281 0.000
X20-X29 Contact with venomous animals and plants
0.719 0.281 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.718 0.281 0.000
K62.0 Anal polyp
0.718 0.282 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.717 0.283 0.000
R62 Lack of expected normal physiological development
0.717 0.283 0.000
R64 Cachexia
0.717 0.283 0.000
R58 Haemorrhage, not elsewhere classified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.716 0.284 0.000
Z10 Routine general health check-up of defined subpopulation
0.716 0.284 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.716 0.284 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.716 0.284 0.000
I51.0 Cardiac septal defect, acquired
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
S00.3 Superficial injury of nose
0.713 0.287 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.712 0.288 0.000
Z01.7 Laboratory examination
0.712 0.288 0.000
Z01.3 Examination of blood pressure
0.712 0.288 0.000
Z01.2 Dental examination
0.712 0.288 0.000
Z01.1 Examination of ears and hearing
0.712 0.288 0.000
Z01.0 Examination of eyes and vision
0.712 0.288 0.000
S27 Injury of other and unspecified intrathoracic organs
0.712 0.288 0.000
R57 Shock, not elsewhere classified
0.712 0.288 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.711 0.289 0.000
Z49.1 Extracorporeal dialysis
0.711 0.289 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.710 0.290 0.000
K03 Other diseases of hard tissues of teeth
0.709 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.708 0.292 0.000
K11.6 Mucocele of salivary gland
0.706 0.294 0.000
I35.0 Aortic (valve) stenosis
0.706 0.294 0.000
S00.5 Superficial injury of lip and oral cavity
0.705 0.294 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.705 0.295 0.000
S82 Fracture of lower leg, including ankle
0.704 0.296 0.000
K66 Other disorders of peritoneum
0.704 0.296 0.000
Z04 Examination and observation for other reasons
0.704 0.296 0.000
Z74 Problems related to care-provider dependency
0.703 0.297 0.000
G64 Other disorders of peripheral nervous system
0.703 0.297 0.000
R46 Symptoms and signs involving appearance and behaviour
0.702 0.297 0.000
R43 Disturbances of smell and taste
0.702 0.297 0.000
V40-V49 Car occupant injured in transport accident
0.702 0.297 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.702 0.298 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.702 0.298 0.000
K12 Stomatitis and related lesions
0.702 0.298 0.000
T93 Sequelae of injuries of lower limb
0.701 0.299 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.700 0.300 0.000
S19 Other and unspecified injuries of neck
0.700 0.300 0.000
W06 Fall involving bed
0.700 0.300 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.700 0.300 0.000
Q35-Q37 Cleft lip and cleft palate
0.700 0.300 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.700 0.300 0.000
G62.8 Other specified polyneuropathies
0.700 0.300 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.699 0.301 0.000
W10 Fall on and from stairs and steps
0.699 0.301 0.000
S11 Open wound of neck
0.699 0.301 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.699 0.301 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.699 0.301 0.000
G92 Toxic encephalopathy
0.699 0.301 0.000
X50-X57 Overexertion, travel and privation
0.699 0.301 0.000
K04.5 Chronic apical periodontitis
0.699 0.301 0.000
F99-F99 Unspecified mental disorder
0.696 0.304 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.696 0.304 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.696 0.304 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.696 0.304 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.696 0.304 0.000
Z03.0 Observation for suspected tuberculosis
0.696 0.304 0.000
Q23.1 Congenital insufficiency of aortic valve
0.695 0.305 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.695 0.305 0.000
Z63 Other problems related to primary support group, including family circumstances
0.695 0.305 0.000
S08 Traumatic amputation of part of head
0.694 0.306 0.000
S07 Crushing injury of head
0.694 0.306 0.000
S04 Injury of cranial nerves
0.694 0.306 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.694 0.306 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.694 0.306 0.000
G60 Hereditary and idiopathic neuropathy
0.694 0.306 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.693 0.306 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.693 0.307 0.000
K02.8 Other dental caries
0.693 0.307 0.000
K02.5 Caries with pulp exposure
0.693 0.307 0.000
K02.4 Odontoclasia
0.693 0.307 0.000
K02.3 Arrested dental caries
0.693 0.307 0.000
K02.2 Caries of cementum
0.693 0.307 0.000
K02.1 Caries of dentin
0.693 0.307 0.000
K02.0 Caries limited to enamel
0.693 0.307 0.000
G43.1 Migraine with aura [classical migraine]
0.692 0.308 0.000
R54 Senility
0.691 0.308 0.000
Z43 Attention to artificial openings
0.691 0.309 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.691 0.309 0.000
Z01.6 Radiological examination, not elsewhere classified
0.690 0.310 0.000
L10-L14 Bullous disorders
0.690 0.310 0.000
G62.2 Polyneuropathy due to other toxic agents
0.688 0.312 0.000
G62.1 Alcoholic polyneuropathy
0.688 0.312 0.000
G62.0 Drug-induced polyneuropathy
0.688 0.312 0.000
R45.2 Unhappiness
0.688 0.312 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.688 0.312 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.688 0.312 0.000
S06.3 Focal brain injury
0.687 0.313 0.000
K04.8 Radicular cyst
0.687 0.313 0.000
I49 Other cardiac arrhythmias
0.686 0.314 0.000
K05.3 Chronic periodontitis
0.685 0.315 0.000
Z53.0 Procedure not carried out because of contraindication
0.685 0.315 0.000
K11.7 Disturbances of salivary secretion
0.684 0.316 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.684 0.316 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.683 0.316 0.000
Z76 Persons encountering health services in other circumstances
0.682 0.318 0.000
W19.4 Street and highway
0.682 0.318 0.000
K11.2 Sialoadenitis
0.682 0.318 0.000
K52.3 Indeterminate colitis
0.681 0.319 0.000
S01 Open wound of head
0.681 0.319 0.000
R71 Abnormality of red blood cells
0.681 0.319 0.000
Z60 Problems related to social environment
0.681 0.319 0.000
S12 Fracture of neck
0.681 0.319 0.000
Q21.0 Ventricular septal defect
0.680 0.320 0.000
R23 Other skin changes
0.679 0.321 0.000
Q27 Other congenital malformations of peripheral vascular system
0.679 0.321 0.000
Q26 Congenital malformations of great veins
0.679 0.321 0.000
Q25 Congenital malformations of great arteries
0.679 0.321 0.000
Q24 Other congenital malformations of heart
0.679 0.321 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.679 0.321 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.679 0.321 0.000
Y35-Y36 Legal intervention and operations of war
0.679 0.321 0.000
Y10-Y34 Event of undetermined intent
0.679 0.321 0.000
Y00-Y09 Assault
0.679 0.321 0.000
X85-X99 Assault
0.679 0.321 0.000
X30-X39 Exposure to forces of nature
0.679 0.321 0.000
X10-X19 Contact with heat and hot substances
0.679 0.321 0.000
X00-X09 Exposure to smoke, fire and flames
0.679 0.321 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.679 0.321 0.000
W75-W84 Other accidental threats to breathing
0.679 0.321 0.000
W65-W74 Accidental drowning and submersion
0.679 0.321 0.000
W50-W64 Exposure to animate mechanical forces
0.679 0.321 0.000
V98-V99 Other and unspecified transport accidents
0.679 0.321 0.000
V95-V97 Air and space transport accidents
0.679 0.321 0.000
V90-V94 Water transport accidents
0.679 0.321 0.000
V70-V79 Bus occupant injured in transport accident
0.679 0.321 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.679 0.321 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.679 0.321 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.679 0.321 0.000
V20-V29 Motorcycle rider injured in transport accident
0.679 0.321 0.000
V01-V09 Pedestrian injured in transport accident
0.679 0.321 0.000
G20 Parkinson's disease
0.678 0.322 0.000
I51.4 Myocarditis, unspecified
0.677 0.322 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.677 0.322 0.000
R41.2 Retrograde amnesia
0.677 0.323 0.000
R41.1 Anterograde amnesia
0.677 0.323 0.000
S14 Injury of nerves and spinal cord at neck level
0.677 0.323 0.000
K10 Other diseases of jaws
0.676 0.324 0.000
I69 Sequelae of cerebrovascular disease
0.675 0.325 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.675 0.325 0.000
S37 Injury of urinary and pelvic organs
0.675 0.325 0.000
S36 Injury of intra-abdominal organs
0.675 0.325 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.675 0.325 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.675 0.325 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.675 0.325 0.000
S31 Open wound of abdomen, lower back and pelvis
0.675 0.325 0.000
Q28 Other congenital malformations of circulatory system
0.675 0.325 0.000
Q00-Q07 Congenital malformations of the nervous system
0.675 0.325 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.675 0.325 0.000
R45.8 Other symptoms and signs involving emotional state
0.674 0.326 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.674 0.326 0.000
S06.5 Traumatic subdural haemorrhage
0.674 0.326 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.674 0.326 0.000
R52.1 Chronic intractable pain
0.673 0.327 0.000
Z00.0 General medical examination
0.673 0.327 0.000
Z75 Problems related to medical facilities and other health care
0.673 0.327 0.000
T91.1 Sequelae of fracture of spine
0.673 0.327 0.000
R50.2 Drug-induced fever
0.672 0.327 0.000
R50.1 Persistent fever
0.672 0.327 0.000
G43.8 Other migraine
0.670 0.330 0.000
G43.3 Complicated migraine
0.670 0.330 0.000
G43.2 Status migrainosus
0.670 0.330 0.000
G43.0 Migraine without aura [common migraine]
0.670 0.330 0.000
L85 Other epidermal thickening
0.670 0.330 0.000
L51 Erythema multiforme
0.670 0.330 0.000
Q60-Q64 Congenital malformations of the urinary system
0.670 0.330 0.000
R40.0 Somnolence
0.670 0.330 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.669 0.331 0.000
R68.8 Other specified general symptoms and signs
0.668 0.332 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.668 0.332 0.000
R25.1 Tremor, unspecified
0.668 0.332 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.668 0.332 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.667 0.332 0.000
G91.1 Obstructive hydrocephalus
0.667 0.332 0.000
T51 Toxic effect of alcohol
0.667 0.333 0.000
R60.1 Generalised oedema
0.667 0.333 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.666 0.334 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.666 0.334 0.000
Q50-Q56 Congenital malformations of genital organs
0.666 0.334 0.000
I35.9 Aortic valve disorder, unspecified
0.666 0.334 0.000
W07 Fall involving chair
0.665 0.335 0.000
S06.80 Other intracranial injuries (without open intracranial wound)
0.665 0.335 0.000
F03 Unspecified dementia
0.663 0.337 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.663 0.337 0.000
I34 Nonrheumatic mitral valve disorders
0.663 0.337 0.000
W08 Fall involving other furniture
0.663 0.337 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.662 0.338 0.000
L58 Radiodermatitis
0.662 0.338 0.000
L55 Sunburn
0.662 0.338 0.000
Z71.8 Other specified counselling
0.662 0.338 0.000
S30.1 Contusion of abdominal wall
0.661 0.339 0.000
G40.8 Other epilepsy
0.661 0.339 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.661 0.339 0.000
G40.5 Special epileptic syndromes
0.661 0.339 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.661 0.339 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.661 0.339 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.660 0.339 0.000
K04.3 Abnormal hard tissue formation in pulp
0.660 0.339 0.000
K04.2 Pulp degeneration
0.660 0.339 0.000
K04.1 Necrosis of pulp
0.660 0.339 0.000
K04.0 Pulpitis
0.660 0.339 0.000
F31 Bipolar affective disorder
0.660 0.340 0.000
S30.0 Contusion of lower back and pelvis
0.660 0.340 0.000
S48 Traumatic amputation of shoulder and upper arm
0.659 0.341 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.659 0.341 0.000
S44 Injury of nerves at shoulder and upper arm level
0.659 0.341 0.000
S41 Open wound of shoulder and upper arm
0.659 0.341 0.000
S47 Crushing injury of shoulder and upper arm
0.659 0.341 0.000
I67.1 Cerebral aneurysm, nonruptured
0.659 0.341 0.000
L53 Other erythematous conditions
0.658 0.342 0.000
Z44 Fitting and adjustment of external prosthetic device
0.656 0.343 0.000
S00.7 Multiple superficial injuries of head
0.655 0.344 0.000
S00.4 Superficial injury of ear
0.655 0.344 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.654 0.346 0.000
F70-F79 Mental retardation
0.654 0.346 0.000
G61.0 Guillain-Barre syndrome
0.654 0.346 0.000
I51.6 Cardiovascular disease, unspecified
0.654 0.346 0.000
I51.5 Myocardial degeneration
0.654 0.346 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.654 0.346 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.654 0.346 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.654 0.346 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.653 0.347 0.000
V80-V89 Other land transport accidents
0.653 0.347 0.000
K52.1 Toxic gastro-enteritis and colitis
0.652 0.348 0.000
Q21.9 Congenital malformation of cardiac septum, unspecified
0.652 0.348 0.000
Q21.8 Other congenital malformations of cardiac septa
0.652 0.348 0.000
Q21.4 Aortopulmonary septal defect
0.652 0.348 0.000
Q21.3 Tetralogy of Fallot
0.652 0.348 0.000
Q21.2 Atrioventricular septal defect
0.652 0.348 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.652 0.348 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.652 0.348 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.651 0.349 0.000
R56.0 Febrile convulsions
0.651 0.349 0.000
T91.3 Sequelae of injury of spinal cord
0.651 0.349 0.000
I31.9 Disease of pericardium, unspecified
0.651 0.349 0.000
I33.9 Acute endocarditis, unspecified
0.650 0.350 0.000
G41.9 Status epilepticus, unspecified
0.650 0.350 0.000
R59.1 Generalised enlarged lymph nodes
0.650 0.350 0.000
K62.8 Other specified diseases of anus and rectum
0.649 0.351 0.000
I15 Secondary hypertension
0.649 0.351 0.000
I13 Hypertensive heart and renal disease
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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