TreeWAS – Variant ID: rs400547

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
E10.9 Without complications	1.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000
E10-E14 Diabetes mellitus	0.991	0.009
L40.9 Psoriasis, unspecified	0.984	0.016
L40 Psoriasis	0.979	0.021
L40-L45 Papulosquamous disorders	0.970	0.030
Chapter IV Endocrine, nutritional and metabolic diseases	0.969	0.031
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.969	0.031
E10.3 With ophthalmic complications	0.967	0.033
# Top node	0.965	0.035
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.961	0.039
Chapter XII Diseases of the skin and subcutaneous tissue	0.958	0.042
M70-M79 Other soft tissue disorders	0.958	0.042
M79 Other soft tissue disorders, not elsewhere classified	0.952	0.048
M79.7 Fibromyalgia	0.944	0.056
T66-T78 Other and unspecified effects of external causes	0.939	0.061
E10.4 With neurological complications	0.924	0.076
M79.79 Fibromyalgia (Site unspecified)	0.923	0.077
Chapter IX Diseases of the circulatory system	0.917	0.083
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.908	0.092
T78 Adverse effects, not elsewhere classified	0.900	0.100
S90-S99 Injuries to the ankle and foot	0.895	0.105
I20-I25 Ischaemic heart diseases	0.892	0.108
M86-M90 Other osteopathies	0.889	0.111
E10.1 With ketoacidosis	0.881	0.119
E14 Unspecified diabetes mellitus	0.881	0.119
Chapter XX External causes of morbidity and mortality	0.878	0.122
M50-M54 Other dorsopathies	0.871	0.129
T78.4 Allergy, unspecified	0.870	0.130
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.868	0.132
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.865	0.135
T20-T25 Burns and corrosions of external body surface, specified by site	0.860	0.140
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.860	0.140
T93 Sequelae of injuries of lower limb	0.858	0.142
M79.70 Fibromyalgia (Multiple sites)	0.858	0.142
I21 Acute myocardial infarction	0.856	0.144
M54 Dorsalgia	0.855	0.145
M79.2 Neuralgia and neuritis, unspecified	0.847	0.153
L40.5 Arthropathic psoriasis	0.844	0.156
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.840	0.160
E65-E68 Obesity and other hyperalimentation	0.838	0.162
E10.5 With peripheral circulatory complications	0.835	0.165
I10-I15 Hypertensive diseases	0.834	0.166
M80-M85 Disorders of bone density and structure	0.834	0.166
M72 Fibroblastic disorders	0.830	0.170
T88 Other complications of surgical and medical care, not elsewhere classified	0.828	0.172
M71 Other bursopathies	0.826	0.174
M89 Other disorders of bone	0.826	0.174
M79.6 Pain in limb	0.824	0.176
I21.9 Acute myocardial infarction, unspecified	0.823	0.177
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.822	0.178
E14.9 Without complications	0.822	0.178
L43 Lichen planus	0.819	0.181
T79-T79 Certain early complications of trauma	0.817	0.183
I70-I79 Diseases of arteries, arterioles and capillaries	0.814	0.186
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.812	0.188
I26 Pulmonary embolism	0.812	0.188
I12 Hypertensive renal disease	0.803	0.197
M65-M68 Disorders of synovium and tendon	0.800	0.200
M54.4 Lumbago with sciatica	0.798	0.202
T36-T50 Poisoning by drugs, medicaments and biological substances	0.796	0.204
T92 Sequelae of injuries of upper limb	0.793	0.207
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.792	0.208
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.789	0.211
M54.9 Dorsalgia, unspecified	0.789	0.211
T88.7 Unspecified adverse effect of drug or medicament	0.787	0.213
S32 Fracture of lumbar spine and pelvis	0.787	0.213
E10.0 With coma	0.786	0.214
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.784	0.216
E16 Other disorders of pancreatic internal secretion	0.781	0.219
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.779	0.221
M54.5 Low back pain	0.779	0.221
E13 Other specified diabetes mellitus	0.779	0.221
M76 Enthesopathies of lower limb, excluding foot	0.777	0.223
S90 Superficial injury of ankle and foot	0.772	0.228
T93.2 Sequelae of other fractures of lower limb	0.769	0.231
E40-E46 Malnutrition	0.768	0.232
M77 Other enthesopathies	0.768	0.232
I21.1 Acute transmural myocardial infarction of inferior wall	0.764	0.236
E66 Obesity	0.763	0.237
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.763	0.237
I20 Angina pectoris	0.762	0.238
T83.0 Mechanical complication of urinary (indwelling) catheter	0.761	0.239
T00-T07 Injuries involving multiple body regions	0.758	0.242
L50-L54 Urticaria and erythema	0.755	0.244
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.753	0.247
M79.67 Pain in limb (Ankle and foot)	0.753	0.247
I12.0 Hypertensive renal disease with renal failure	0.753	0.247
S20-S29 Injuries to the thorax	0.751	0.249
L40.0 Psoriasis vulgaris	0.750	0.250
I05-I09 Chronic rheumatic heart diseases	0.750	0.250
M54.96 Dorsalgia, unspecified (Lumbar region)	0.749	0.251
M54.56 Low back pain (Lumbar region)	0.749	0.251
M65 Synovitis and tenosynovitis	0.747	0.253
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.746	0.253
T21 Burn and corrosion of trunk	0.745	0.255
T66 Unspecified effects of radiation	0.743	0.257
T68 Hypothermia	0.742	0.258
S91 Open wound of ankle and foot	0.739	0.261
E11 Non-insulin-dependent diabetes mellitus	0.737	0.263
M89.0 Algoneurodystrophy	0.736	0.264
Y60-Y69 Misadventures to patients during surgical and medical care	0.734	0.266
E10.2 With renal complications	0.733	0.267
S50-S59 Injuries to the elbow and forearm	0.733	0.267
I77 Other disorders of arteries and arterioles	0.732	0.268
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.731	0.269
I24 Other acute ischaemic heart diseases	0.731	0.269
Y84.6 Urinary catheterisation	0.730	0.270
M54.46 Lumbago with sciatica (Lumbar region)	0.725	0.275
M71.2 Synovial cyst of popliteal space [Baker]	0.724	0.276
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.720	0.280
I20.9 Angina pectoris, unspecified	0.720	0.280
Chapter XIV Diseases of the genitourinary system	0.718	0.282
E10.8 With unspecified complications	0.717	0.283
E10.7 With multiple complications	0.717	0.283
E10.6 With other specified complications	0.717	0.283
S92 Fracture of foot, except ankle	0.714	0.286
E12 Malnutrition-related diabetes mellitus	0.711	0.289
M80 Osteoporosis with pathological fracture	0.709	0.291
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.709	0.291
T78.3 Angioneurotic oedema	0.708	0.292
I71 Aortic aneurysm and dissection	0.708	0.292
T79 Certain early complications of trauma, not elsewhere classified	0.707	0.293
N20-N23 Urolithiasis	0.705	0.295
T92.2 Sequelae of fracture at wrist and hand level	0.705	0.295
M91-M94 Chondropathies	0.703	0.297
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.703	0.297
N21 Calculus of lower urinary tract	0.703	0.297
L40.8 Other psoriasis	0.702	0.298
L40.4 Guttate psoriasis	0.702	0.298
L40.3 Pustulosis palmaris et plantaris	0.702	0.298
L40.2 Acrodermatitis continua	0.702	0.298
L40.1 Generalised pustular psoriasis	0.702	0.298
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.702	0.298
M86 Osteomyelitis	0.702	0.298
N21.0 Calculus in bladder	0.701	0.299
I12.9 Hypertensive renal disease without renal failure	0.699	0.301
L44 Other papulosquamous disorders	0.696	0.304
L41 Parapsoriasis	0.696	0.304
L45 Papulosquamous disorders in diseases classified elsewhere	0.696	0.304
L42 Pityriasis rosea	0.696	0.304
T33-T35 Frostbite	0.695	0.305
T26-T28 Burns and corrosions confined to eye and internal organs	0.695	0.305
M89.9 Disorder of bone, unspecified	0.693	0.307
Chapter XVI Certain conditions originating in the perinatal period	0.692	0.308
L43.9 Lichen planus, unspecified	0.691	0.309
T93.1 Sequelae of fracture of femur	0.691	0.309
M60-M63 Disorders of muscles	0.688	0.311
L10-L14 Bullous disorders	0.687	0.313
M73 Soft tissue disorders in diseases classified elsewhere	0.687	0.313
M65.3 Trigger finger	0.687	0.313
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.687	0.313
E16.2 Hypoglycaemia, unspecified	0.687	0.313
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.686	0.314
S99 Other and unspecified injuries of ankle and foot	0.684	0.316
M79.9 Soft tissue disorder, unspecified	0.683	0.317
M79.4 Hypertrophy of (infrapatellar) fat pad	0.683	0.317
M79.3 Panniculitis, unspecified	0.683	0.317
M79.65 Pain in limb (Pelvic region and thigh)	0.679	0.321
S36 Injury of intra-abdominal organs	0.679	0.321
M54.94 Dorsalgia, unspecified (Thoracic region)	0.679	0.321
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.678	0.322
M79.61 Pain in limb (Shoulder region)	0.678	0.322
Chapter XXII Codes for special purposes	0.678	0.322
X60-X84 Intentional self-harm	0.677	0.323
M54.47 Lumbago with sciatica (Lumbosacral region)	0.677	0.323
M79.78 Fibromyalgia (Other)	0.676	0.323
M79.77 Fibromyalgia (Ankle and foot)	0.676	0.323
M79.76 Fibromyalgia (Lower leg)	0.676	0.323
M79.75 Fibromyalgia (Pelvic region and thigh)	0.676	0.323
M79.74 Fibromyalgia (Hand)	0.676	0.323
M79.73 Fibromyalgia (Forearm)	0.676	0.323
M79.72 Fibromyalgia (Upper arm)	0.676	0.323
M79.71 Fibromyalgia (Shoulder region)	0.676	0.323
T78.0 Anaphylactic shock due to adverse food reaction	0.675	0.325
T98 Sequelae of other and unspecified effects of external causes	0.674	0.326
S32.0 Fracture of lumbar vertebra	0.674	0.326
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.674	0.326
Y84.2 Radiological procedure and radiotherapy	0.674	0.326
I72 Other aneurysm	0.673	0.327
T75 Effects of other external causes	0.673	0.327
T74 Maltreatment syndromes	0.673	0.327
T73 Effects of other deprivation	0.673	0.327
T70 Effects of air pressure and water pressure	0.673	0.327
T69 Other effects of reduced temperature	0.673	0.327
T67 Effects of heat and light	0.673	0.327
T71 Asphyxiation	0.673	0.327
M89.04 Algoneurodystrophy (Hand)	0.671	0.329
T58 Toxic effect of carbon monoxide	0.671	0.329
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.670	0.330
N10-N16 Renal tubulo-interstitial diseases	0.670	0.330
I77.1 Stricture of artery	0.669	0.331
M70 Soft tissue disorders related to use, overuse and pressure	0.669	0.331
M79.1 Myalgia	0.667	0.333
I23 Certain current complications following acute myocardial infarction	0.667	0.333
S70-S79 Injuries to the hip and thigh	0.665	0.335
I11 Hypertensive heart disease	0.665	0.335
M79.64 Pain in limb (Hand)	0.664	0.336
X10-X19 Contact with heat and hot substances	0.664	0.336
T21.2 Burn of second degree of trunk	0.663	0.337
N25-N29 Other disorders of kidney and ureter	0.663	0.337
I21.3 Acute transmural myocardial infarction of unspecified site	0.663	0.337
M72.2 Plantar fascial fibromatosis	0.662	0.338
M87 Osteonecrosis	0.662	0.338
T59 Toxic effect of other gases, fumes and vapours	0.660	0.340
W50-W64 Exposure to animate mechanical forces	0.659	0.341
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.658	0.342
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.658	0.342
I00-I02 Acute rheumatic fever	0.657	0.343
I22 Subsequent myocardial infarction	0.654	0.346
M79.0 Rheumatism, unspecified	0.654	0.346
E66.9 Obesity, unspecified	0.654	0.346
X20-X29 Contact with venomous animals and plants	0.654	0.346
M45-M49 Spondylopathies	0.653	0.347
I24.9 Acute ischaemic heart disease, unspecified	0.653	0.347
X58-X59 Accidental exposure to other and unspecified factors	0.652	0.348
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.652	0.348
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.652	0.348
T95 Sequelae of burns, corrosions and frostbite	0.651	0.349
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.651	0.349
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.651	0.349
E66.8 Other obesity	0.650	0.350
E11.6 With other specified complications	0.649	0.351
T94 Sequelae of injuries involving multiple and unspecified body regions	0.648	0.352
T20 Burn and corrosion of head and neck	0.648	0.352
X50-X57 Overexertion, travel and privation	0.647	0.353
M84 Disorders of continuity of bone	0.647	0.353
N17-N19 Renal failure	0.647	0.353
T88.5 Other complications of anaesthesia	0.646	0.354
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.646	0.354
T78.9 Adverse effect, unspecified	0.645	0.355
T78.8 Other adverse effects, not elsewhere classified	0.645	0.355
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.645	0.355
M65.34 Trigger finger-Hand	0.644	0.356
W20-W49 Exposure to inanimate mechanical forces	0.644	0.356
E50-E64 Other nutritional deficiencies	0.643	0.357
S98 Traumatic amputation of ankle and foot	0.642	0.358
S97 Crushing injury of ankle and foot	0.642	0.358
S96 Injury of muscle and tendon at ankle and foot level	0.642	0.358
S95 Injury of blood vessels at ankle and foot level	0.642	0.358
S94 Injury of nerves at ankle and foot level	0.642	0.358
Y84.0 Cardiac catheterisation	0.641	0.359
I07 Rheumatic tricuspid valve diseases	0.641	0.359
T88.4 Failed or difficult intubation	0.640	0.360
L53 Other erythematous conditions	0.640	0.360
I15 Secondary hypertension	0.638	0.362
Q20-Q28 Congenital malformations of the circulatory system	0.637	0.363
L20-L30 Dermatitis and eczema	0.637	0.363
S90.8 Other superficial injuries of ankle and foot	0.636	0.364
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.635	0.365
N18 Chronic renal failure	0.635	0.365
S32.5 Fracture of pubis	0.635	0.365
I77.9 Disorder of arteries and arterioles, unspecified	0.634	0.366
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.634	0.366
M00-M03 Infectious arthropathies	0.633	0.367
T78.1 Other adverse food reactions, not elsewhere classified	0.632	0.368
E14.8 With unspecified complications	0.631	0.368
E14.7 With multiple complications	0.631	0.368
E14.6 With other specified complications	0.631	0.368
E14.5 With peripheral circulatory complications	0.631	0.368
E14.4 With neurological complications	0.631	0.368
E14.2 Withrenal complications	0.631	0.368
E14.1 With ketoacidosis	0.631	0.368
E14.0 With coma	0.631	0.368
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.631	0.369
M77.9 Enthesopathy, unspecified	0.631	0.369
S90.3 Contusion of other and unspecified parts of foot	0.630	0.369
Y35-Y36 Legal intervention and operations of war	0.630	0.370
Y10-Y34 Event of undetermined intent	0.630	0.370
Y00-Y09 Assault	0.630	0.370
X85-X99 Assault	0.630	0.370
X30-X39 Exposure to forces of nature	0.630	0.370
X00-X09 Exposure to smoke, fire and flames	0.630	0.370
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.630	0.370
W75-W84 Other accidental threats to breathing	0.630	0.370
W65-W74 Accidental drowning and submersion	0.630	0.370
V98-V99 Other and unspecified transport accidents	0.630	0.370
V95-V97 Air and space transport accidents	0.630	0.370
V90-V94 Water transport accidents	0.630	0.370
V70-V79 Bus occupant injured in transport accident	0.630	0.370
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.630	0.370
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.630	0.370
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.630	0.370
V01-V09 Pedestrian injured in transport accident	0.630	0.370
M65.4 Radial styloid tenosynovitis [de Quervain]	0.629	0.371
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.629	0.371
M79.28 Neuralgia and neuritis, unspecified (Other)	0.628	0.372
T79.3 Post-traumatic wound infection, not elsewhere classified	0.628	0.372
T93.0 Sequelae of open wound of lower limb	0.627	0.373
M65.1 Other infective (teno)synovitis	0.627	0.373
E13.9 Without complications	0.627	0.373
S91.3 Open wound of other parts of foot	0.627	0.373
M81 Osteoporosis without pathological fracture	0.627	0.373
Y86 Sequelae of other accidents	0.626	0.374
M88 Paget's disease of bone [osteitis deformans]	0.626	0.374
S32.7 Multiple fractures of lumbar spine and pelvis	0.626	0.374
T63 Toxic effect of contact with venomous animals	0.625	0.375
M53 Other dorsopathies, not elsewhere classified	0.625	0.375
E46 Unspecified protein-energy malnutrition	0.625	0.375
V80-V89 Other land transport accidents	0.624	0.376
E16.0 Drug-induced hypoglycaemia without coma	0.623	0.377
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.622	0.377
S37 Injury of urinary and pelvic organs	0.622	0.377
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.622	0.377
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.622	0.377
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.622	0.377
S31 Open wound of abdomen, lower back and pelvis	0.622	0.377
L43.8 Other lichen planus	0.621	0.379
M82 Osteoporosis in diseases classified elsewhere	0.620	0.379
M89.8 Other specified disorders of bone	0.619	0.380
I21.0 Acute transmural myocardial infarction of anterior wall	0.619	0.381
T86 Failure and rejection of transplanted organs and tissues	0.618	0.382
T25 Burn and corrosion of ankle and foot	0.617	0.383
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.617	0.383
E15 Nondiabetic hypoglycaemic coma	0.616	0.384
Y89 Sequelae of other external causes	0.616	0.384
S40-S49 Injuries to the shoulder and upper arm	0.615	0.385
T93.8 Sequelae of other specified injuries of lower limb	0.615	0.385
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.615	0.385
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.615	0.385
T93.4 Sequelae of injury of nerve of lower limb	0.615	0.385
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.615	0.385
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.615	0.385
I21.X Presumed acute myicardial infaction (unconfirmed)	0.614	0.386
T11 Other injuries of upper limb, level unspecified	0.614	0.386
N28 Other disorders of kidney and ureter, not elsewhere classified	0.614	0.386
M54.8 Other dorsalgia	0.613	0.387
M54.0 Panniculitis affecting regions of neck and back	0.613	0.387
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.613	0.387
T87 Complications peculiar to reattachment and amputation	0.613	0.387
T93.9 Sequelae of unspecified injury of lower limb	0.613	0.387
S32.3 Fracture of ilium	0.613	0.387
E11.5 With peripheral circulatory complications	0.611	0.389
S10-S19 Injuries to the neck	0.611	0.389
M76.6 Achilles tendinitis	0.611	0.389
M79.69 Pain in limb (Site unspecified)	0.610	0.389
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.610	0.390
Q80-Q89 Other congenital malformations	0.610	0.390
T02 Fractures involving multiple body regions	0.608	0.392
M40-M43 Deforming dorsopathies	0.607	0.393
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.607	0.393
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.607	0.393
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.607	0.393
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.607	0.393
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.607	0.393
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.607	0.393
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.607	0.393
M71.3 Other bursal cyst	0.607	0.393
M76.8 Other enthesopathies of lower limb, excluding foot	0.606	0.394
T15-T19 Effects of foreign body entering through natural orifice	0.605	0.395
M79.5 Residual foreign body in soft tissue	0.604	0.395
S22 Fracture of rib(s), sternum and thoracic spine	0.603	0.396
T13 Other injuries of lower limb, level unspecified	0.603	0.397
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.603	0.397
I28 Other diseases of pulmonary vessels	0.602	0.398
T82.1 Mechanical complication of cardiac electronic device	0.601	0.399
E67 Other hyperalimentation	0.601	0.399
E68 Sequelae of hyperalimentation	0.601	0.399
S54 Injury of nerves at forearm level	0.601	0.399
T83.1 Mechanical complication of other urinary devices and implants	0.600	0.399
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.600	0.400
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.599	0.401
E16.1 Other hypoglycaemia	0.599	0.401
I13 Hypertensive heart and renal disease	0.598	0.402
M83 Adult osteomalacia	0.598	0.402
M72.9 Fibroblastic disorder, unspecified	0.595	0.405
M72.8 Other fibroblastic disorders	0.595	0.405
M72.6 Necrotizing fasciitis	0.595	0.405
M72.5 Fasciitis, not elsewhere classified	0.595	0.405
M72.4 Pseudosarcomatous fibromatosis	0.595	0.405
M72.3 Nodular fasciitis	0.595	0.405
M72.1 Knuckle pads	0.595	0.405
M90 Osteopathies in diseases classified elsewhere	0.594	0.406
T50.9 Other and unspecified drugs, medicaments and biological substances	0.594	0.406
T88.9 Complication of surgical and medical care, unspecified	0.594	0.406
T88.3 Malignant hyperthermia due to anaesthesis	0.594	0.406
T88.2 Shock due to anaesthesia	0.594	0.406
T88.1 Other complications following immunisation, not elsewhere classified	0.594	0.406
T88.0 Infection following immunisation	0.594	0.406
M80.0 Postmenopausal osteoporosis with pathological fracture	0.593	0.407
T23 Burn and corrosion of wrist and hand	0.593	0.407
S30 Superficial injury of abdomen, lower back and pelvis	0.593	0.407
T14 Injury of unspecified body region	0.593	0.407
S32.00 Fracture of lumbar vertebra (closed)	0.593	0.407
V10-V19 Pedal cyclist injured in transport accident	0.592	0.408
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.592	0.408
M71.9 Bursopathy, unspecified	0.592	0.408
M71.8 Other specified bursopathies	0.592	0.408
M71.5 Other bursitis, not elsewhere classified	0.592	0.408
M71.4 Calcium deposit in bursa	0.592	0.408
M71.1 Other infective bursitis	0.592	0.408
M71.0 Abscess of bursa	0.592	0.408
M89.6 Osteopathy after poliomyelitis	0.592	0.408
M89.5 Osteolysis	0.592	0.408
M89.4 Other hypertrophic osteo-arthropathy	0.592	0.408
M89.3 Hypertrophy of bone	0.592	0.408
M89.2 Other disorders of bone development and growth	0.592	0.408
M89.1 Epiphyseal arrest	0.592	0.408
Y52 Agents primarily affecting the cardiovascular system	0.592	0.408
S29 Other and unspecified injuries of thorax	0.591	0.409
M79.68 Pain in limb (Other)	0.591	0.409
E11.0 With coma	0.590	0.410
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.589	0.410
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.589	0.410
T83.2 Mechanical complication of graft of urinary organ	0.589	0.410
T31 Burns classified according to extent of body surface involved	0.587	0.413
L43.3 Subacute (active) lichen planus	0.587	0.413
L43.2 Lichenoid drug reaction	0.587	0.413
L43.1 Bullous lichen planus	0.587	0.413
L43.0 Hypertrophic lichen planus	0.587	0.413
N28.1 Cyst of kidney, acquired	0.585	0.415
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.584	0.416
M54.3 Sciatica	0.584	0.416
T36 Poisoning by systemic antibiotics	0.584	0.416
M77.5 Other enthesopathy of foot	0.583	0.417
T65 Toxic effect of other and unspecified substances	0.582	0.417
T62 Toxic effect of other noxious substances eaten as food	0.582	0.417
T61 Toxic effect of noxious substances eaten as seafood	0.582	0.417
T60 Toxic effect of pesticides	0.582	0.417
T57 Toxic effect of other inorganic substances	0.582	0.417
T56 Toxic effect of metals	0.582	0.417
T54 Toxic effect of corrosive substances	0.582	0.417
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.582	0.417
T52 Toxic effect of organic solvents	0.582	0.417
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.582	0.417
T55 Toxic effect of soaps and detergents	0.582	0.417
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.582	0.418
N18.2 Chronic kidney disease, stage 2	0.581	0.419
N18.3 Chronic kidney disease, stage 3	0.576	0.424
Y88 Sequelae of surgical and medical care as external cause	0.575	0.424
S59 Other and unspecified injuries of forearm	0.575	0.425
V40-V49 Car occupant injured in transport accident	0.575	0.425
N18.9 Chronic renal failure, unspecified	0.575	0.425
Q38-Q45 Other congenital malformations of the digestive system	0.574	0.426
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.573	0.427
Q60-Q64 Congenital malformations of the urinary system	0.572	0.428
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.572	0.428
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.572	0.428
M54.44 Lumbago with sciatica-Thoracic	0.572	0.428
M54.43 Lumbago with sciatica-Cervicothoracic	0.572	0.428
M54.42 Lumbago with sciatica-Cervical	0.572	0.428
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.572	0.428
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.572	0.428
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.570	0.429
T41 Poisoning by anaesthetics and therapeutic gases	0.570	0.429
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.570	0.429
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.570	0.430
I72.9 Aneurysm of unspecified site	0.569	0.431
M66 Spontaneous rupture of synovium and tendon	0.569	0.431
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.568	0.431
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.568	0.431
T92.4 Sequelae of injury of nerve of upper limb	0.568	0.431
I74 Arterial embolism and thrombosis	0.568	0.432
M86.9 Osteomyelitis, unspecified	0.568	0.432
I05 Rheumatic mitral valve diseases	0.568	0.432
M79.63 Pain in limb (Forearm)	0.566	0.434
T09 Other injuries of spine and trunk, level unspecified	0.566	0.434
T12.X1 Fracture of lower limb, level unspecified (open)	0.566	0.434
T12.X0 Fracture of lower limb, level unspecified (closed)	0.566	0.434
T12 Fracture of lower limb, level unspecified	0.566	0.434
T10.X1 Fracture of upper limb, level unspecified (open)	0.566	0.434
T10.X0 Fracture of upper limb, level unspecified (closed)	0.566	0.434
T10 Fracture of upper limb, level unspecified	0.566	0.434
T08.X1 Fracture of spine, level unspecified (open)	0.566	0.434
T08.X0 Fracture of spine, level unspecified (closed)	0.566	0.434
T08 Fracture of spine, level unspecified	0.566	0.434
T90 Sequelae of injuries of head	0.566	0.434
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.566	0.434
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.566	0.434
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.566	0.434
M54.92 Dorsalgia, unspecified (Cervical region)	0.566	0.434
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.566	0.434
T79.7 Traumatic subcutaneous emphysema	0.565	0.435
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.564	0.435
S32.2 Fracture of coccyx	0.564	0.435
M54.6 Pain in thoracic spine	0.563	0.437
L28 Lichen simplex chronicus and prurigo	0.563	0.437
V20-V29 Motorcycle rider injured in transport accident	0.563	0.437
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.563	0.437
I07.1 Tricuspid insufficiency	0.563	0.437
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.562	0.438
S92.0 Fracture of calcaneus	0.562	0.438
M85 Other disorders of bone density and structure	0.562	0.438
T78.2 Anaphylactic shock, unspecified	0.562	0.438
M89.98 Disorder of bone, unspecified (Other)	0.562	0.438
I09 Other rheumatic heart diseases	0.561	0.439
E16.9 Disorder of pancreatic internal secretion, unspecified	0.560	0.440
E16.8 Other specified disorders of pancreatic internal secretion	0.560	0.440
E16.4 Abnormal secretion of gastrin	0.560	0.440
E16.3 Increased secretion of glucagon	0.560	0.440
T92.8 Sequelae of other specified injuries of upper limb	0.560	0.440
I21.4 Acute subendocardial myocardial infarction	0.560	0.440
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.559	0.441
Q35-Q37 Cleft lip and cleft palate	0.559	0.441
Q30-Q34 Congenital malformations of the respiratory system	0.559	0.441
M54.55 Low back pain (Thoracolumbar region)	0.559	0.441
M54.54 Low back pain-Thoracic	0.559	0.441
M54.53 Low back pain-Cervicothoracic	0.559	0.441
M54.52 Low back pain-Cervical	0.559	0.441
M54.51 Low back pain-Occipit-atl-axl	0.559	0.441

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations