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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs41264825
log Bayes Factor = 16.4549
Chromosome 1   position 159,810,939  (GRCh37) Explore rs41264825 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.997 0.003 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.996 0.004 0.000
S60-S69 Injuries to the wrist and hand
0.996 0.004 0.000
J90-J94 Other diseases of pleura
0.996 0.004 0.000
Z50 Care involving use of rehabilitation procedures
0.992 0.008 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.991 0.009 0.000
S61 Open wound of wrist and hand
0.990 0.010 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.987 0.013 0.000
Z50.1 Other physical therapy
0.987 0.013 0.000
M05-M14 Inflammatory polyarthropathies
0.986 0.014 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.985 0.015 0.000
Z04 Examination and observation for other reasons
0.984 0.016 0.000
S61.8 Open wound of other parts of wrist and hand
0.979 0.021 0.000
H30-H36 Disorders of choroid and retina
0.979 0.021 0.000
J92 Pleural plaque
0.978 0.022 0.000
C25 Malignant neoplasm of pancreas
0.977 0.023 0.000
C18 Malignant neoplasm of colon
0.968 0.032 0.000
E10 Insulin-dependent diabetes mellitus
0.966 0.034 0.000
E11.9 Without complications
0.965 0.035 0.000
M06 Other rheumatoid arthritis
0.963 0.037 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.960 0.040 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.959 0.041 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.947 0.053 0.000
M06.9 Rheumatoid arthritis, unspecified
0.946 0.054 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.942 0.058 0.000
S40-S49 Injuries to the shoulder and upper arm
0.942 0.058 0.000
H35 Other retinal disorders
0.937 0.063 0.000
J92.9 Pleural plaque without asbestos
0.936 0.064 0.000
S00-S09 Injuries to the head
0.936 0.064 0.000
Z04.3 Examination and observation following other accident
0.932 0.068 0.000
H36 Retinal disorders in diseases classified elsewhere
0.930 0.070 0.000
M10 Gout
0.929 0.071 0.000
Z12 Special screening examination for neoplasms
0.922 0.078 0.000
H25-H28 Disorders of lens
0.917 0.083 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.916 0.084 0.000
J09-J18 Influenza and pneumonia
0.914 0.086 0.000
C25.9 Pancreas, unspecified
0.914 0.086 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.912 0.088 0.000
J40-J47 Chronic lower respiratory diseases
0.911 0.089 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.908 0.092 0.000
Z04.9 Examination and observation for unspecified reason
0.906 0.094 0.000
C21 Malignant neoplasm of anus and anal canal
0.898 0.102 0.000
E11.3 With ophthalmic complications
0.898 0.102 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.896 0.104 0.000
H36.0 Diabetic retinopathy
0.894 0.106 0.000
S70-S79 Injuries to the hip and thigh
0.894 0.106 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.893 0.107 0.000
H40-H42 Glaucoma
0.893 0.107 0.000
J92.0 Pleural plaque with presence of asbestos
0.892 0.108 0.000
E11.4 With neurological complications
0.892 0.108 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.890 0.110 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.889 0.111 0.000
M10.9 Gout, unspecified
0.888 0.112 0.000
J95-J99 Other diseases of the respiratory system
0.888 0.112 0.000
J94 Other pleural conditions
0.887 0.113 0.000
J91 Pleural effusion in conditions classified elsewhere
0.884 0.116 0.000
M45-M49 Spondylopathies
0.882 0.118 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.876 0.124 0.000
T81 Complications of procedures, not elsewhere classified
0.875 0.125 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.873 0.127 0.000
S06 Intracranial injury
0.871 0.129 0.000
Z50.5 Speech therapy
0.869 0.131 0.000
C18.2 Ascending colon
0.866 0.134 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.864 0.136 0.000
S42 Fracture of shoulder and upper arm
0.862 0.138 0.000
S20-S29 Injuries to the thorax
0.860 0.140 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.859 0.141 0.000
E11.2 With renal complications
0.859 0.141 0.000
Z85 Personal history of malignant neoplasm
0.858 0.142 0.000
Chapter XX External causes of morbidity and mortality
0.857 0.143 0.000
E10.4 With neurological complications
0.856 0.143 0.000
D68 Other coagulation defects
0.856 0.144 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.855 0.145 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.854 0.146 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.849 0.151 0.000
C25.0 Head of pancreas
0.845 0.155 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.843 0.157 0.000
H43-H45 Disorders of vitreous body and globe
0.843 0.157 0.000
Chapter IX Diseases of the circulatory system
0.842 0.158 0.000
S61.7 Multiple open wounds of wrist and hand
0.841 0.159 0.000
J18 Pneumonia, organism unspecified
0.839 0.161 0.000
C18.9 Colon, unspecified
0.838 0.162 0.000
M10.99 Gout, unspecified (Site unspecified)
0.838 0.162 0.000
J44 Other chronic obstructive pulmonary disease
0.834 0.166 0.000
C50-C50 Malignant neoplasm of breast
0.834 0.166 0.000
E70-E90 Metabolic disorders
0.830 0.170 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.829 0.171 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.826 0.174 0.000
S90-S99 Injuries to the ankle and foot
0.826 0.174 0.000
C18.0 Caecum
0.824 0.176 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.821 0.179 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.820 0.180 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.820 0.180 0.000
D50-D53 Nutritional anaemias
0.820 0.180 0.000
H35.3 Degeneration of macula and posterior pole
0.819 0.181 0.000
H40 Glaucoma
0.819 0.181 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.817 0.183 0.000
M91-M94 Chondropathies
0.815 0.185 0.000
H25 Senile cataract
0.815 0.185 0.000
E10.5 With peripheral circulatory complications
0.813 0.187 0.000
E11.0 With coma
0.813 0.187 0.000
T86 Failure and rejection of transplanted organs and tissues
0.813 0.187 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.812 0.188 0.000
E65-E68 Obesity and other hyperalimentation
0.812 0.188 0.000
Z95.4 Presence of other heart-valve replacement
0.809 0.191 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.805 0.195 0.000
Z04.1 Examination and observation following transport accident
0.804 0.195 0.000
Z95.2 Presence of prosthetic heart valve
0.803 0.197 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.801 0.199 0.000
S67 Crushing injury of wrist and hand
0.800 0.200 0.000
S61.0 Open wound of finger(s) without damage to nail
0.796 0.204 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.794 0.206 0.000
S64 Injury of nerves at wrist and hand level
0.792 0.208 0.000
C17 Malignant neoplasm of small intestine
0.792 0.208 0.000
Chapter XXII Codes for special purposes
0.792 0.208 0.000
S80-S89 Injuries to the knee and lower leg
0.792 0.208 0.000
J60-J70 Lung diseases due to external agents
0.790 0.210 0.000
H35.6 Retinal haemorrhage
0.790 0.210 0.000
C25.1 Body of pancreas
0.787 0.213 0.000
Z98 Other postsurgical states
0.785 0.215 0.000
S10-S19 Injuries to the neck
0.785 0.215 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.784 0.216 0.000
E10.1 With ketoacidosis
0.783 0.217 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.781 0.219 0.000
M60-M63 Disorders of muscles
0.781 0.219 0.000
M07 Psoriatic and enteropathic arthropathies
0.780 0.220 0.000
S50-S59 Injuries to the elbow and forearm
0.779 0.221 0.000
C25.2 Tail of pancreas
0.779 0.221 0.000
M05 Seropositive rheumatoid arthritis
0.779 0.221 0.000
C21.0 Anus, unspecified
0.778 0.222 0.000
Z89 Acquired absence of limb
0.777 0.223 0.000
Z50.0 Cardiac rehabilitation
0.776 0.223 0.000
J18.9 Pneumonia, unspecified
0.775 0.225 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.775 0.225 0.000
H44 Disorders of globe
0.775 0.225 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.773 0.227 0.000
Z95.1 Presence of aortocoronary bypass graft
0.771 0.229 0.000
J40 Bronchitis, not specified as acute or chronic
0.771 0.229 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.771 0.229 0.000
H26 Other cataract
0.771 0.229 0.000
D60-D64 Aplastic and other anaemias
0.770 0.230 0.000
D51 Vitamin B12 deficiency anaemia
0.769 0.230 0.000
Z12.8 Special screening examination for neoplasm of other sites
0.769 0.231 0.000
E10.3 With ophthalmic complications
0.769 0.231 0.000
S02 Fracture of skull and facial bones
0.769 0.231 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.768 0.232 0.000
E83 Disorders of mineral metabolism
0.767 0.233 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.766 0.234 0.000
E11.1 With ketoacidosis
0.765 0.235 0.000
I60-I69 Cerebrovascular diseases
0.765 0.235 0.000
H25.1 Senile nuclear cataract
0.765 0.235 0.000
Z90.5 Acquired absence of kidney
0.764 0.236 0.000
C18.7 Sigmoid colon
0.764 0.236 0.000
E20-E35 Disorders of other endocrine glands
0.763 0.237 0.000
D00-D09 In situ neoplasms
0.763 0.237 0.000
C51-C58 Malignant neoplasms of female genital organs
0.763 0.237 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.762 0.238 0.000
S42.2 Fracture of upper end of humerus
0.761 0.239 0.000
H31 Other disorders of choroid
0.761 0.239 0.000
Q50-Q56 Congenital malformations of genital organs
0.761 0.239 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.760 0.240 0.000
Q60-Q64 Congenital malformations of the urinary system
0.760 0.240 0.000
H40.2 Primary angle-closure glaucoma
0.759 0.241 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.759 0.241 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.758 0.242 0.000
J47 Bronchiectasis
0.758 0.242 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.757 0.243 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.756 0.244 0.000
Z90.1 Acquired absence of breast(s)
0.755 0.245 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.755 0.245 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.755 0.245 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.755 0.245 0.000
M45 Ankylosing spondylitis
0.755 0.245 0.000
E10.2 With renal complications
0.754 0.246 0.000
J94.8 Other specified pleural conditions
0.753 0.247 0.000
Chapter VI Diseases of the nervous system
0.753 0.247 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.753 0.247 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.753 0.247 0.000
J86 Pyothorax
0.751 0.249 0.000
Z86 Personal history of certain other diseases
0.751 0.249 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.750 0.250 0.000
Z49 Care involving dialysis
0.749 0.250 0.000
S41 Open wound of shoulder and upper arm
0.749 0.251 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.749 0.251 0.000
M70-M79 Other soft tissue disorders
0.748 0.252 0.000
C21.1 Anal canal
0.747 0.253 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.747 0.253 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.746 0.254 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.746 0.254 0.000
E83.5 Disorders of calcium metabolism
0.742 0.258 0.000
J94.2 Haemothorax
0.741 0.259 0.000
D68.0 Von Willebrand's disease
0.741 0.259 0.000
Chapter XIV Diseases of the genitourinary system
0.741 0.259 0.000
H26.4 After-cataract
0.738 0.262 0.000
S05 Injury of eye and orbit
0.738 0.262 0.000
S79 Other and unspecified injuries of hip and thigh
0.737 0.263 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.737 0.263 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.736 0.263 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.736 0.264 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.736 0.264 0.000
S61.1 Open wound of finger(s) with damage to nail
0.736 0.264 0.000
H35.4 Peripheral retinal degeneration
0.736 0.264 0.000
M46 Other inflammatory spondylopathies
0.735 0.265 0.000
M65-M68 Disorders of synovium and tendon
0.735 0.265 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.735 0.265 0.000
I69 Sequelae of cerebrovascular disease
0.734 0.266 0.000
Z98.0 Intestinal bypass and anastomosis status
0.734 0.266 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.734 0.266 0.000
S42.0 Fracture of clavicle
0.733 0.267 0.000
M00-M03 Infectious arthropathies
0.733 0.267 0.000
Z50.2 Alcohol rehabilitation
0.733 0.267 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.731 0.269 0.000
M40-M43 Deforming dorsopathies
0.730 0.270 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.730 0.270 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.728 0.271 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.728 0.272 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.728 0.272 0.000
W20-W49 Exposure to inanimate mechanical forces
0.728 0.272 0.000
S69 Other and unspecified injuries of wrist and hand
0.726 0.274 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.726 0.274 0.000
Z90.0 Acquired absence of part of head and neck
0.726 0.274 0.000
H44.2 Degenerative myopia
0.726 0.274 0.000
J90 Pleural effusion, not elsewhere classified
0.725 0.275 0.000
H35.5 Hereditary retinal dystrophy
0.725 0.275 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.724 0.276 0.000
H25.8 Other senile cataract
0.724 0.276 0.000
J95.8 Other postprocedural respiratory disorders
0.723 0.277 0.000
E14 Unspecified diabetes mellitus
0.722 0.277 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.722 0.278 0.000
H35.9 Retinal disorder, unspecified
0.721 0.279 0.000
S70 Superficial injury of hip and thigh
0.721 0.279 0.000
S06.0 Concussion
0.721 0.279 0.000
S06.5 Traumatic subdural haemorrhage
0.720 0.279 0.000
Z04.8 Examination and observation for other specified reasons
0.719 0.281 0.000
D46 Myelodysplastic syndromes
0.719 0.281 0.000
M86-M90 Other osteopathies
0.718 0.282 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C20 Malignant neoplasm of rectum
0.716 0.284 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.716 0.284 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.716 0.284 0.000
C23 Malignant neoplasm of gallbladder
0.716 0.284 0.000
C50 Malignant neoplasm of breast
0.716 0.284 0.000
J93 Pneumothorax
0.715 0.285 0.000
E11.8 With unspecified complications
0.715 0.285 0.000
E11.7 With multiple complications
0.715 0.285 0.000
E11.6 With other specified complications
0.715 0.285 0.000
S72 Fracture of femur
0.715 0.285 0.000
X60-X84 Intentional self-harm
0.714 0.286 0.000
Z10 Routine general health check-up of defined subpopulation
0.714 0.286 0.000
S65 Injury of blood vessels at wrist and hand level
0.714 0.286 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.712 0.288 0.000
Z50.6 Orthoptic training
0.711 0.289 0.000
Z50.3 Drug rehabilitation
0.711 0.289 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.711 0.289 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.711 0.289 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.710 0.289 0.000
J95.0 Tracheostomy malfunction
0.710 0.290 0.000
Z44 Fitting and adjustment of external prosthetic device
0.707 0.292 0.000
M14 Arthropathies in other diseases classified elsewhere
0.707 0.293 0.000
M12 Other specific arthropathies
0.707 0.293 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.707 0.293 0.000
M08 Juvenile arthritis
0.707 0.293 0.000
C15 Malignant neoplasm of oesophagus
0.707 0.293 0.000
D63.0 Anaemia in neoplastic disease
0.706 0.294 0.000
H34 Retinal vascular occlusions
0.706 0.294 0.000
T51 Toxic effect of alcohol
0.706 0.294 0.000
T66-T78 Other and unspecified effects of external causes
0.706 0.294 0.000
Z04.6 General psychiatric examination, requested by authority
0.705 0.295 0.000
Z04.5 Examination and observation following other inflicted injury
0.705 0.295 0.000
Z04.4 Examination and observation following alleged rape and seduction
0.705 0.295 0.000
Z04.2 Examination and observation following work accident
0.705 0.295 0.000
Z04.0 Blood-alcohol and blood-drug test
0.705 0.295 0.000
H52 Disorders of refraction and accommodation
0.705 0.295 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.705 0.295 0.000
S09 Other and unspecified injuries of head
0.705 0.295 0.000
T86.1 Kidney transplant failure and rejection
0.704 0.296 0.000
M06.0 Seronegative rheumatoid arthritis
0.703 0.296 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.702 0.298 0.000
H30 Chorioretinal inflammation
0.702 0.298 0.000
Z43 Attention to artificial openings
0.702 0.298 0.000
H35.7 Separation of retinal layers
0.702 0.298 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.702 0.298 0.000
C25.8 Overlapping lesion of pancreas
0.701 0.299 0.000
C25.7 Other parts of pancreas
0.701 0.299 0.000
C25.4 Endocrine pancreas
0.701 0.299 0.000
C25.3 Pancreatic duct
0.701 0.299 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.700 0.300 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.700 0.300 0.000
Z50.8 Care involving use of rehabilitation procedures
0.699 0.301 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.698 0.301 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.697 0.303 0.000
M10.96 Gout, unspecified (Lower leg)
0.696 0.304 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.696 0.304 0.000
E13 Other specified diabetes mellitus
0.695 0.305 0.000
J18.1 Lobar pneumonia, unspecified
0.695 0.305 0.000
C18.3 Hepatic flexure
0.694 0.306 0.000
C18.8 Overlapping lesion of colon
0.694 0.306 0.000
C18.5 Splenic flexure
0.694 0.306 0.000
C18.1 Appendix
0.694 0.306 0.000
C16 Malignant neoplasm of stomach
0.693 0.307 0.000
D68.5 Primary Thrombophilia
0.693 0.307 0.000
E10.8 With unspecified complications
0.692 0.307 0.000
E10.7 With multiple complications
0.692 0.307 0.000
E10.6 With other specified complications
0.692 0.307 0.000
E10.0 With coma
0.692 0.307 0.000
C77.1 Intrathoracic lymph nodes
0.691 0.309 0.000
D68.6 Other Thrombophilia
0.691 0.309 0.000
M06.8 Other specified rheumatoid arthritis
0.690 0.310 0.000
M06.4 Inflammatory polyarthropathy
0.690 0.310 0.000
M06.3 Rheumatoid nodule
0.690 0.310 0.000
M06.2 Rheumatoid bursitis
0.690 0.310 0.000
M06.1 Adult-onset Still's disease
0.690 0.310 0.000
H35.0 Background retinopathy and retinal vascular changes
0.690 0.310 0.000
Z45 Adjustment and management of implanted device
0.689 0.311 0.000
T79-T79 Certain early complications of trauma
0.689 0.311 0.000
H10-H13 Disorders of conjunctiva
0.689 0.311 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.689 0.311 0.000
S42.20 Fracture of upper end of humerus (closed)
0.689 0.311 0.000
T87 Complications peculiar to reattachment and amputation
0.688 0.312 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.688 0.312 0.000
M94 Other disorders of cartilage
0.688 0.312 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.687 0.313 0.000
H55-H59 Other disorders of eye and adnexa
0.686 0.314 0.000
S29 Other and unspecified injuries of thorax
0.686 0.314 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.685 0.315 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.685 0.315 0.000
Z52 Donors of organs and tissues
0.685 0.315 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.684 0.316 0.000
S82 Fracture of lower leg, including ankle
0.683 0.317 0.000
J42 Unspecified chronic bronchitis
0.683 0.317 0.000
D68.8 Other specified coagulation defects
0.683 0.317 0.000
C18.6 Descending colon
0.683 0.317 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.682 0.317 0.000
H53-H54 Visual disturbances and blindness
0.682 0.318 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.681 0.319 0.000
T85.2 Mechanical complication of intraocular lens
0.679 0.321 0.000
N30-N39 Other diseases of urinary system
0.679 0.321 0.000
D55-D59 Haemolytic anaemias
0.679 0.321 0.000
E10.9 Without complications
0.679 0.321 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.679 0.321 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.678 0.322 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.678 0.322 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.678 0.322 0.000
E66 Obesity
0.678 0.322 0.000
S60 Superficial injury of wrist and hand
0.677 0.322 0.000
E11.5 With peripheral circulatory complications
0.676 0.324 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.676 0.324 0.000
Z84 Family history of other conditions
0.676 0.324 0.000
Z81 Family history of mental and behavioural disorders
0.676 0.324 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.675 0.324 0.000
H40.1 Primary open-angle glaucoma
0.675 0.325 0.000
S48 Traumatic amputation of shoulder and upper arm
0.675 0.325 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.675 0.325 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.675 0.325 0.000
S44 Injury of nerves at shoulder and upper arm level
0.675 0.325 0.000
S47 Crushing injury of shoulder and upper arm
0.675 0.325 0.000
M48 Other spondylopathies
0.674 0.326 0.000
J46 Status asthmaticus
0.674 0.326 0.000
I61 Intracerebral haemorrhage
0.674 0.326 0.000
S68 Traumatic amputation of wrist and hand
0.674 0.326 0.000
Z99.1 Dependence on respirator
0.673 0.327 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.672 0.327 0.000
H35.2 Other proliferative retinopathy
0.672 0.328 0.000
H35.1 Retinopathy of prematurity
0.672 0.328 0.000
Q80-Q89 Other congenital malformations
0.671 0.329 0.000
S08 Traumatic amputation of part of head
0.671 0.329 0.000
S07 Crushing injury of head
0.671 0.329 0.000
S04 Injury of cranial nerves
0.671 0.329 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.671 0.329 0.000
Z86.7 Personal history of diseases of the circulatory system
0.671 0.329 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.670 0.329 0.000
Z90.3 Acquired absence of part of stomach
0.670 0.330 0.000
Z40 Prophylactic surgery
0.670 0.330 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.669 0.331 0.000
H49 Paralytic strabismus
0.668 0.332 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.666 0.333 0.000
D45 Polycythaemia vera
0.666 0.334 0.000
S51 Open wound of forearm
0.666 0.334 0.000
M10.4 Other secondary gout
0.666 0.334 0.000
M10.3 Gout due to impairment of renal function
0.666 0.334 0.000
M10.2 Drug-induced gout
0.666 0.334 0.000
M10.1 Lead-induced gout
0.666 0.334 0.000
M10.0 Idiopathic gout
0.666 0.334 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.666 0.334 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.666 0.334 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.666 0.334 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.665 0.335 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.664 0.336 0.000
J11 Influenza, virus not identified
0.664 0.336 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.663 0.337 0.000
N17-N19 Renal failure
0.663 0.337 0.000
M13 Other arthritis
0.662 0.338 0.000
S42.3 Fracture of shaft of humerus
0.661 0.339 0.000
Z12.9 Special screening examination for neoplasm, unspecified
0.661 0.339 0.000
Z12.6 Special screening examination for neoplasm of bladder
0.661 0.339 0.000
Z12.4 Special screening examination for neoplasm of cervix
0.661 0.339 0.000
Z12.3 Special screening examination for neoplasm of breast
0.661 0.339 0.000
Z12.2 Special screening examination for neoplasm of respiratory organs
0.661 0.339 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.661 0.339 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.660 0.340 0.000
Z89.4 Acquired absence of foot and ankle
0.659 0.341 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.658 0.341 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.658 0.342 0.000
Z54 Convalescence
0.658 0.342 0.000
W00-W19 Falls
0.658 0.342 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.657 0.342 0.000
H27 Other disorders of lens
0.657 0.342 0.000
C80 Malignant neoplasm without specification of site
0.657 0.343 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.657 0.343 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.657 0.343 0.000
C50.4 Upper-outer quadrant of breast
0.657 0.343 0.000
D68.9 Coagulation defect, unspecified
0.656 0.344 0.000
C18.4 Transverse colon
0.656 0.344 0.000
J17 Pneumonia in diseases classified elsewhere
0.655 0.345 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.655 0.345 0.000
J12 Viral pneumonia, not elsewhere classified
0.655 0.345 0.000
J14 Pneumonia due to Haemophilus influenzae
0.655 0.345 0.000
J09 Influenza due to certain identified influenza virus
0.655 0.345 0.000
Z90.8 Acquired absence of other organs
0.655 0.345 0.000
I10-I15 Hypertensive diseases
0.655 0.345 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.654 0.346 0.000
S02.1 Fracture of base of skull
0.654 0.346 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.654 0.346 0.000
Q35-Q37 Cleft lip and cleft palate
0.654 0.346 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.654 0.346 0.000
Q00-Q07 Congenital malformations of the nervous system
0.654 0.346 0.000
S06.2 Diffuse brain injury
0.654 0.346 0.000
J10 Influenza due to identified influenza virus
0.654 0.346 0.000
J41 Simple and mucopurulent chronic bronchitis
0.653 0.347 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.653 0.347 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.651 0.348 0.000
Z90.7 Acquired absence of genital organ(s)
0.651 0.349 0.000
Z99.3 Dependence on wheelchair
0.651 0.349 0.000
S92 Fracture of foot, except ankle
0.650 0.350 0.000
Z83 Family history of other specific disorders
0.648 0.351 0.000
S06.3 Focal brain injury
0.648 0.352 0.000
Z90.2 Acquired absence of lung [part of]
0.648 0.352 0.000
T88.4 Failed or difficult intubation
0.648 0.352 0.000
E87.5 Hyperkalaemia
0.648 0.352 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.647 0.353 0.000
S06.8 Other intracranial injuries
0.647 0.353 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.647 0.353 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.645 0.355 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.645 0.355 0.000
S50 Superficial injury of forearm
0.644 0.355 0.000
V80-V89 Other land transport accidents
0.644 0.355 0.000
C21.8 Overlapping lesion of rectum, anus and anal canal
0.644 0.356 0.000
C21.2 Cloacogenic zone
0.644 0.356 0.000
C17.0 Duodenum
0.644 0.356 0.000
S40 Superficial injury of shoulder and upper arm
0.643 0.357 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.642 0.357 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.642 0.358 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.642 0.358 0.000
I67 Other cerebrovascular diseases
0.642 0.358 0.000
T81.9 Unspecified complication of procedure
0.641 0.358 0.000
S42.00 Fracture of clavicle (closed)
0.641 0.359 0.000
S78 Traumatic amputation of hip and thigh
0.641 0.359 0.000
S77 Crushing injury of hip and thigh
0.641 0.359 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.641 0.359 0.000
S75 Injury of blood vessels at hip and thigh level
0.641 0.359 0.000
S74 Injury of nerves at hip and thigh level
0.641 0.359 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.641 0.359 0.000
S71 Open wound of hip and thigh
0.641 0.359 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.641 0.359 0.000
D67 Hereditary factor IX deficiency
0.641 0.359 0.000
D66 Hereditary factor VIII deficiency
0.641 0.359 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.641 0.359 0.000
H42 Glaucoma in diseases classified elsewhere
0.640 0.359 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.639 0.361 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.639 0.361 0.000
D69 Purpura and other haemorrhagic conditions
0.638 0.362 0.000
M77 Other enthesopathies
0.637 0.362 0.000
M10.98 Gout, unspecified (Other)
0.637 0.363 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.637 0.363 0.000
M10.94 Gout, unspecified (Hand)
0.637 0.363 0.000
M10.93 Gout, unspecified (Forearm)
0.637 0.363 0.000
M10.92 Gout, unspecified (Upper arm)
0.637 0.363 0.000
M10.91 Gout, unspecified (Shoulder region)
0.637 0.363 0.000
M10.90 Gout, unspecified (Multiple sites)
0.637 0.363 0.000
I20-I25 Ischaemic heart diseases
0.637 0.363 0.000
J96 Respiratory failure, not elsewhere classified
0.636 0.364 0.000
J94.9 Pleural condition, unspecified
0.636 0.364 0.000
J94.1 Fibrothorax
0.636 0.364 0.000
J94.0 Chylous effusion
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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