TreeWAS – Variant ID: rs41267086

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E10-E14 Diabetes mellitus	0.000	0.000	1.000
N40-N51 Diseases of male genital organs	1.000	0.000	0.000
Chapter XIV Diseases of the genitourinary system	1.000	0.000	0.000
E11 Non-insulin-dependent diabetes mellitus	0.000	0.000	1.000
N40 Hyperplasia of prostate	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.001	0.999
E03.9 Hypothyroidism, unspecified	0.000	0.001	0.999
E03 Other hypothyroidism	0.000	0.001	0.999
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
E11.3 With ophthalmic complications	0.000	0.002	0.998
N20-N23 Urolithiasis	0.998	0.002	0.000
K90.0 Coeliac disease	0.000	0.007	0.993
E10 Insulin-dependent diabetes mellitus	0.000	0.009	0.991
# Top node	0.990	0.010	0.000
Chapter IX Diseases of the circulatory system	0.984	0.016	0.000
E11.4 With neurological complications	0.000	0.016	0.984
N23 Unspecified renal colic	0.982	0.018	0.000
I30-I52 Other forms of heart disease	0.979	0.021	0.000
N42 Other disorders of prostate	0.979	0.021	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.978	0.022	0.000
Chapter XX External causes of morbidity and mortality	0.973	0.027	0.000
I46 Cardiac arrest	0.971	0.029	0.000
Chapter VIII Diseases of the ear and mastoid process	0.971	0.029	0.000
I47 Paroxysmal tachycardia	0.969	0.031	0.000
I10-I15 Hypertensive diseases	0.969	0.031	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.968	0.032	0.000
E10.3 With ophthalmic complications	0.000	0.042	0.958
I47.1 Supraventricular tachycardia	0.958	0.042	0.000
M70-M79 Other soft tissue disorders	0.958	0.042	0.000
I46.0 Cardiac arrest with successful resuscitation	0.954	0.046	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.952	0.048	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.950	0.050	0.000
N42.8 Other specified disorders of prostate	0.950	0.050	0.000
N30-N39 Other diseases of urinary system	0.950	0.050	0.000
I10 Essential (primary) hypertension	0.941	0.059	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.931	0.069	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.928	0.072	0.000
M79.6 Pain in limb	0.927	0.073	0.000
H65-H75 Diseases of middle ear and mastoid	0.926	0.074	0.000
J45.9 Asthma, unspecified	0.000	0.075	0.925
N41 Inflammatory diseases of prostate	0.923	0.077	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.920	0.080	0.000
M80-M85 Disorders of bone density and structure	0.920	0.080	0.000
N86 Erosion and ectropion of cervix uteri	0.917	0.083	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.915	0.085	0.000
I83 Varicose veins of lower extremities	0.914	0.086	0.000
N20 Calculus of kidney and ureter	0.914	0.086	0.000
H60-H62 Diseases of external ear	0.912	0.088	0.000
N10-N16 Renal tubulo-interstitial diseases	0.908	0.092	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.908	0.092	0.000
N21 Calculus of lower urinary tract	0.906	0.094	0.000
Y86 Sequelae of other accidents	0.905	0.095	0.000
N88 Other noninflammatory disorders of cervix uteri	0.904	0.096	0.000
E14 Unspecified diabetes mellitus	0.000	0.100	0.900
E11.9 Without complications	0.000	0.103	0.897
I49 Other cardiac arrhythmias	0.894	0.106	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.108	0.892
M79.7 Fibromyalgia	0.891	0.109	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.885	0.115	0.000
S20-S29 Injuries to the thorax	0.883	0.117	0.000
H73 Other disorders of tympanic membrane	0.878	0.122	0.000
N41.1 Chronic prostatitis	0.878	0.122	0.000
S32 Fracture of lumbar spine and pelvis	0.876	0.124	0.000
M50-M54 Other dorsopathies	0.876	0.124	0.000
M40-M43 Deforming dorsopathies	0.874	0.126	0.000
I46.9 Cardiac arrest, unspecified	0.873	0.127	0.000
S60-S69 Injuries to the wrist and hand	0.872	0.128	0.000
H61 Other disorders of external ear	0.871	0.129	0.000
N36 Other disorders of urethra	0.870	0.130	0.000
E50-E64 Other nutritional deficiencies	0.000	0.131	0.869
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.865	0.135	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.864	0.136	0.000
N81 Female genital prolapse	0.860	0.140	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.859	0.141	0.000
N39 Other disorders of urinary system	0.858	0.142	0.000
E20-E35 Disorders of other endocrine glands	0.000	0.142	0.858
I38 Endocarditis, valve unspecified	0.854	0.146	0.000
E10.9 Without complications	0.000	0.149	0.851
M79.79 Fibromyalgia (Site unspecified)	0.849	0.151	0.000
S90-S99 Injuries to the ankle and foot	0.847	0.153	0.000
H73.8 Other specified disorders of tympanic membrane	0.844	0.156	0.000
M79.66 Pain in limb (Lower leg)	0.843	0.157	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.842	0.158	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.159	0.841
N21.0 Calculus in bladder	0.840	0.160	0.000
Y84.8 Other medical procedures	0.828	0.172	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.180	0.820
S22 Fracture of rib(s), sternum and thoracic spine	0.819	0.181	0.000
N89 Other noninflammatory disorders of vagina	0.816	0.184	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.185	0.815
N83.0 Follicular cyst of ovary	0.811	0.189	0.000
E10.1 With ketoacidosis	0.000	0.190	0.810
N20.1 Calculus of ureter	0.805	0.195	0.000
N42.9 Disorder of prostate, unspecified	0.805	0.195	0.000
M79.62 Pain in limb (Upper arm)	0.804	0.196	0.000
E11.1 With ketoacidosis	0.000	0.198	0.802
S62 Fracture at wrist and hand level	0.802	0.198	0.000
N39.3 Stress incontinence	0.801	0.199	0.000
M54 Dorsalgia	0.801	0.199	0.000
E21.0 Primary hyperparathyroidism	0.000	0.201	0.799
M79.1 Myalgia	0.798	0.202	0.000
I49.5 Sick sinus syndrome	0.798	0.202	0.000
N81.6 Rectocele	0.796	0.204	0.000
V80-V89 Other land transport accidents	0.793	0.207	0.000
M84 Disorders of continuity of bone	0.793	0.207	0.000
N25-N29 Other disorders of kidney and ureter	0.792	0.207	0.000
S61 Open wound of wrist and hand	0.792	0.208	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.791	0.209	0.000
I49.8 Other specified cardiac arrhythmias	0.791	0.209	0.000
I15 Secondary hypertension	0.790	0.210	0.000
E06 Thyroiditis	0.000	0.211	0.789
Chapter XXII Codes for special purposes	0.786	0.213	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.786	0.214	0.000
M80 Osteoporosis with pathological fracture	0.785	0.215	0.000
E14.3 With ophthalmic complications	0.000	0.216	0.784
M86-M90 Other osteopathies	0.783	0.217	0.000
N13 Obstructive and reflux uropathy	0.783	0.217	0.000
S22.4 Multiple fractures of ribs	0.783	0.217	0.000
H72 Perforation of tympanic membrane	0.778	0.222	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.778	0.222	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.777	0.223	0.000
E10.4 With neurological complications	0.000	0.225	0.775
N20.0 Calculus of kidney	0.774	0.226	0.000
T90 Sequelae of injuries of head	0.772	0.228	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.228	0.772
T92 Sequelae of injuries of upper limb	0.771	0.229	0.000
H61.8 Other specified disorders of external ear	0.770	0.229	0.000
S62.6 Fracture of other finger	0.770	0.230	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.765	0.235	0.000
E10.5 With peripheral circulatory complications	0.000	0.236	0.764
I11 Hypertensive heart disease	0.763	0.237	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.763	0.237	0.000
N36.2 Urethral caruncle	0.762	0.238	0.000
V10-V19 Pedal cyclist injured in transport accident	0.762	0.238	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.762	0.238	0.000
T79-T79 Certain early complications of trauma	0.761	0.239	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.761	0.239	0.000
X50-X57 Overexertion, travel and privation	0.761	0.239	0.000
N81.9 Female genital prolapse, unspecified	0.760	0.240	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.240	0.760
I47.0 Reentry ventricular arrhythmia	0.759	0.241	0.000
S32.0 Fracture of lumbar vertebra	0.759	0.241	0.000
S22.40 Multiple fractures of ribs (closed)	0.757	0.243	0.000
M82 Osteoporosis in diseases classified elsewhere	0.756	0.244	0.000
N32 Other disorders of bladder	0.753	0.247	0.000
M79.64 Pain in limb (Hand)	0.753	0.247	0.000
M79.61 Pain in limb (Shoulder region)	0.753	0.247	0.000
E53 Deficiency of other B group vitamins	0.000	0.248	0.752
M79.2 Neuralgia and neuritis, unspecified	0.749	0.251	0.000
M76 Enthesopathies of lower limb, excluding foot	0.749	0.251	0.000
M43 Other deforming dorsopathies	0.749	0.251	0.000
H61.1 Non-infective disorders of pinna	0.749	0.251	0.000
I47.2 Ventricular tachycardia	0.748	0.252	0.000
M60-M63 Disorders of muscles	0.746	0.254	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.745	0.255	0.000
I88 Nonspecific lymphadenitis	0.745	0.255	0.000
M91-M94 Chondropathies	0.744	0.256	0.000
E14.9 Without complications	0.000	0.257	0.743
Y48 Anaesthetics and therapeutic gases	0.742	0.258	0.000
I12 Hypertensive renal disease	0.742	0.258	0.000
T00-T07 Injuries involving multiple body regions	0.741	0.259	0.000
S31 Open wound of abdomen, lower back and pelvis	0.740	0.259	0.000
N42.2 Atrophy of prostate	0.739	0.261	0.000
N34 Urethritis and urethral syndrome	0.736	0.264	0.000
S62.60 Fracture of other finger (closed)	0.734	0.266	0.000
E10.2 With renal complications	0.000	0.267	0.733
N13.3 Other and unspecified hydronephrosis	0.733	0.267	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.732	0.267	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.731	0.269	0.000
X10-X19 Contact with heat and hot substances	0.730	0.270	0.000
V40-V49 Car occupant injured in transport accident	0.730	0.270	0.000
N81.1 Cystocele	0.729	0.271	0.000
M41 Scoliosis	0.728	0.271	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.728	0.272	0.000
H74 Other disorders of middle ear and mastoid	0.727	0.273	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.726	0.274	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.725	0.275	0.000
S92 Fracture of foot, except ankle	0.724	0.276	0.000
I30 Acute pericarditis	0.722	0.278	0.000
I82 Other venous embolism and thrombosis	0.722	0.278	0.000
M79.67 Pain in limb (Ankle and foot)	0.722	0.278	0.000
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.717
N51 Disorders of male genital organs in diseases classified elsewhere	0.717	0.283	0.000
N46 Male infertility	0.717	0.283	0.000
N44 Torsion of testis	0.717	0.283	0.000
E11.8 With unspecified complications	0.000	0.283	0.717
E11.7 With multiple complications	0.000	0.283	0.717
E11.6 With other specified complications	0.000	0.283	0.717
M54.2 Cervicalgia	0.717	0.283	0.000
S32.3 Fracture of ilium	0.717	0.283	0.000
N83.2 Other and unspecified ovarian cysts	0.716	0.284	0.000
Y88 Sequelae of surgical and medical care as external cause	0.716	0.284	0.000
E03.8 Other specified hypothyroidism	0.000	0.284	0.716
E03.5 Myxoedema coma	0.000	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.000	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.000	0.284	0.716
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.284	0.716
E03.1 Congenital hypothyroidism without goitre	0.000	0.284	0.716
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.284	0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.284	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.284	0.716
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.284	0.716
I37 Pulmonary valve disorders	0.716	0.284	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.715	0.284	0.000
V20-V29 Motorcycle rider injured in transport accident	0.714	0.286	0.000
N20.9 Urinary calculus, unspecified	0.714	0.286	0.000
N42.0 Calculus of prostate	0.712	0.288	0.000
H61.2 Impacted cerumen	0.711	0.289	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.711	0.289	0.000
E10.8 With unspecified complications	0.000	0.289	0.711
E10.7 With multiple complications	0.000	0.289	0.711
E10.6 With other specified complications	0.000	0.289	0.711
E10.0 With coma	0.000	0.289	0.711
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.711	0.289	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.710	0.290	0.000
E11.2 With renal complications	0.000	0.291	0.709
I49.4 Other and unspecified premature depolarisation	0.708	0.291	0.000
M79.60 Pain in limb (Multiple sites)	0.708	0.292	0.000
I49.0 Ventricular fibrillation and flutter	0.708	0.292	0.000
M71 Other bursopathies	0.707	0.293	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.706	0.294	0.000
N41.0 Acute prostatitis	0.706	0.294	0.000
I00-I02 Acute rheumatic fever	0.706	0.294	0.000
S36 Injury of intra-abdominal organs	0.705	0.295	0.000
S10-S19 Injuries to the neck	0.703	0.297	0.000
I52 Other heart disorders in diseases classified elsewhere	0.702	0.298	0.000
I48 Atrial fibrillation and flutter	0.702	0.298	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.702	0.298	0.000
I41 Myocarditis in diseases classified elsewhere	0.702	0.298	0.000
I40 Acute myocarditis	0.702	0.298	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.702	0.298	0.000
I32 Pericarditis in diseases classified elsewhere	0.702	0.298	0.000
T93 Sequelae of injuries of lower limb	0.702	0.298	0.000
N42.3 Dysplasia of prostate	0.702	0.298	0.000
N39.8 Other specified disorders of urinary system	0.702	0.298	0.000
N42.1 Congestion and haemorrhage of prostate	0.701	0.299	0.000
N50 Other disorders of male genital organs	0.700	0.300	0.000
E11.0 With coma	0.000	0.300	0.700
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.700	0.300	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.700	0.300	0.000
I35 Nonrheumatic aortic valve disorders	0.698	0.302	0.000
S32.5 Fracture of pubis	0.698	0.302	0.000
Y35-Y36 Legal intervention and operations of war	0.697	0.302	0.000
Y10-Y34 Event of undetermined intent	0.697	0.302	0.000
Y00-Y09 Assault	0.697	0.302	0.000
X85-X99 Assault	0.697	0.302	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.697	0.302	0.000
X30-X39 Exposure to forces of nature	0.697	0.302	0.000
X20-X29 Contact with venomous animals and plants	0.697	0.302	0.000
X00-X09 Exposure to smoke, fire and flames	0.697	0.302	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.697	0.302	0.000
W75-W84 Other accidental threats to breathing	0.697	0.302	0.000
W65-W74 Accidental drowning and submersion	0.697	0.302	0.000
V98-V99 Other and unspecified transport accidents	0.697	0.302	0.000
V95-V97 Air and space transport accidents	0.697	0.302	0.000
V90-V94 Water transport accidents	0.697	0.302	0.000
V70-V79 Bus occupant injured in transport accident	0.697	0.302	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.697	0.302	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.697	0.302	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.697	0.302	0.000
V01-V09 Pedestrian injured in transport accident	0.697	0.302	0.000
N36.9 Urethral disorder, unspecified	0.697	0.303	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.697	0.303	0.000
I46.1 Sudden cardiac death, so described	0.696	0.304	0.000
I13 Hypertensive heart and renal disease	0.694	0.305	0.000
T33-T35 Frostbite	0.694	0.306	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.694	0.306	0.000
T66-T78 Other and unspecified effects of external causes	0.693	0.307	0.000
M54.4 Lumbago with sciatica	0.692	0.308	0.000
N81.3 Complete uterovaginal prolapse	0.691	0.309	0.000
M51 Other intervertebral disk disorders	0.691	0.309	0.000
M00-M03 Infectious arthropathies	0.690	0.310	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.688	0.312	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.688	0.312	0.000
M73 Soft tissue disorders in diseases classified elsewhere	0.687	0.313	0.000
Y84.4 Aspiration of fluid	0.685	0.315	0.000
T91 Sequelae of injuries of neck and trunk	0.685	0.315	0.000
Y52 Agents primarily affecting the cardiovascular system	0.685	0.315	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.684	0.316	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.684	0.316	0.000
W20-W49 Exposure to inanimate mechanical forces	0.683	0.316	0.000
N98 Complications associated with artificial fertilisation	0.682	0.317	0.000
N91 Absent, scanty and rare menstruation	0.682	0.317	0.000
N96 Habitual aborter	0.682	0.317	0.000
N39.9 Disorder of urinary system, unspecified	0.682	0.318	0.000
M79.9 Soft tissue disorder, unspecified	0.681	0.319	0.000
M79.3 Panniculitis, unspecified	0.681	0.319	0.000
N37 Urethral disorders in diseases classified elsewhere	0.681	0.319	0.000
N33 Bladder disorders in diseases classified elsewhere	0.681	0.319	0.000
N36.1 Urethral diverticulum	0.681	0.319	0.000
N39.4 Other specified urinary incontinence	0.681	0.319	0.000
H71 Cholesteatoma of middle ear	0.680	0.320	0.000
W50-W64 Exposure to animate mechanical forces	0.680	0.320	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.679	0.321	0.000
N85.0 Endometrial glandular hyperplasia	0.678	0.322	0.000
M79.10 Myalgia (Multiple sites)	0.677	0.323	0.000
E55 Vitamin D deficiency	0.000	0.324	0.676
S32.00 Fracture of lumbar vertebra (closed)	0.675	0.325	0.000
N90.7 Vulvar cyst	0.674	0.326	0.000
S91 Open wound of ankle and foot	0.672	0.328	0.000
H80-H83 Diseases of inner ear	0.672	0.328	0.000
S30.1 Contusion of abdominal wall	0.671	0.329	0.000
M79.69 Pain in limb (Site unspecified)	0.671	0.329	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.671	0.329	0.000
N36.8 Other specified disorders of urethra	0.670	0.330	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.669	0.331	0.000
M54.1 Radiculopathy	0.669	0.331	0.000
E53.8 Deficiency of other specified B group vitamins	0.000	0.331	0.669
M79.15 Myalgia (Pelvic region and thigh)	0.668	0.331	0.000
I34 Nonrheumatic mitral valve disorders	0.668	0.332	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.668	0.332	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.668	0.332	0.000
M79.63 Pain in limb (Forearm)	0.667	0.333	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.667	0.333	0.000
S61.8 Open wound of other parts of wrist and hand	0.667	0.333	0.000
M85 Other disorders of bone density and structure	0.667	0.333	0.000
M72 Fibroblastic disorders	0.667	0.333	0.000
S50-S59 Injuries to the elbow and forearm	0.666	0.334	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.665	0.335	0.000
S37 Injury of urinary and pelvic organs	0.665	0.335	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.665	0.335	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.665	0.335	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.665	0.335	0.000
Y89 Sequelae of other external causes	0.665	0.335	0.000
M79.68 Pain in limb (Other)	0.665	0.335	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.664	0.336	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.664	0.336	0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.664	0.336	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.664	0.336	0.000
H70 Mastoiditis and related conditions	0.664	0.336	0.000
H68 Eustachian salpingitis and obstruction	0.664	0.336	0.000
H67 Otitis media in diseases classified elsewhere	0.664	0.336	0.000
I15.9 Seconday hypertension, unspecified	0.663	0.337	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.662	0.337	0.000
C67 Malignant neoplasm of bladder	0.662	0.338	0.000
N41.8 Other inflammatory diseases of prostate	0.662	0.338	0.000
N41.3 Prostatocystitis	0.662	0.338	0.000
N41.2 Abscess of prostate	0.662	0.338	0.000
C64-C68 Malignant neoplasms of urinary tract	0.661	0.339	0.000
S61.1 Open wound of finger(s) with damage to nail	0.660	0.340	0.000
Chapter II Neoplasms	0.660	0.340	0.000
M83 Adult osteomalacia	0.659	0.340	0.000
N32.0 Bladder-neck obstruction	0.659	0.341	0.000
S61.0 Open wound of finger(s) without damage to nail	0.659	0.341	0.000
C67.9 Bladder, unspecified	0.658	0.342	0.000
Y44 Agents primarily affecting blood constituents	0.656	0.343	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.656	0.344	0.000
S27 Injury of other and unspecified intrathoracic organs	0.655	0.345	0.000
I49.1 Atrial premature depolarisation	0.655	0.345	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.654	0.346	0.000
H60 Otitis externa	0.653	0.346	0.000
I05-I09 Chronic rheumatic heart diseases	0.652	0.348	0.000
M81 Osteoporosis without pathological fracture	0.652	0.348	0.000
S92.3 Fracture of metatarsal bone	0.652	0.348	0.000
H61.3 Acquired stenosis of external ear canal	0.652	0.348	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.651	0.349	0.000
N15 Other renal tubulo-interstitial diseases	0.651	0.349	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.651	0.349	0.000
T95 Sequelae of burns, corrosions and frostbite	0.651	0.349	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.651	0.349	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.651	0.349	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.650	0.349	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.649	0.350	0.000
N21.8 Other lower urinary tract calculus	0.649	0.350	0.000
N21.1 Calculus in urethra	0.649	0.350	0.000
M54.22 Cervicalgia (Cervical region)	0.649	0.351	0.000
N88.4 Hypertrophic elongation of cervix uteri	0.648	0.352	0.000
N88.3 Incompetence of cervix uteri	0.648	0.352	0.000
N88.1 Old laceration of cervix uteri	0.648	0.352	0.000
N88.0 Leukoplakia of cervix uteri	0.648	0.352	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.352	0.648
N11 Chronic tubulo-interstitial nephritis	0.648	0.352	0.000
O60-O75 Complications of labour and delivery	0.648	0.352	0.000
E11.5 With peripheral circulatory complications	0.000	0.354	0.646
S29 Other and unspecified injuries of thorax	0.645	0.354	0.000
T90.9 Sequelae of unspecified injury of head	0.645	0.355	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.645	0.355	0.000
E14.8 With unspecified complications	0.000	0.355	0.645
E14.7 With multiple complications	0.000	0.355	0.645
E14.6 With other specified complications	0.000	0.355	0.645
E14.5 With peripheral circulatory complications	0.000	0.355	0.645
E14.4 With neurological complications	0.000	0.355	0.645
E14.2 Withrenal complications	0.000	0.355	0.645
E14.1 With ketoacidosis	0.000	0.355	0.645
E14.0 With coma	0.000	0.355	0.645
T98 Sequelae of other and unspecified effects of external causes	0.645	0.355	0.000
I36 Nonrheumatic tricuspid valve disorders	0.644	0.356	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.644	0.356	0.000
M77 Other enthesopathies	0.644	0.356	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.643	0.357	0.000
M79.0 Rheumatism, unspecified	0.643	0.357	0.000
N82 Fistulae involving female genital tract	0.642	0.358	0.000
I49.2 Junctional premature depolarisation	0.641	0.359	0.000
M79.70 Fibromyalgia (Multiple sites)	0.641	0.359	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.641	0.359	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.640	0.360	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.360	0.639
M79.78 Fibromyalgia (Other)	0.639	0.361	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.639	0.361	0.000
M79.76 Fibromyalgia (Lower leg)	0.639	0.361	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.639	0.361	0.000
M79.74 Fibromyalgia (Hand)	0.639	0.361	0.000
M79.73 Fibromyalgia (Forearm)	0.639	0.361	0.000
M79.72 Fibromyalgia (Upper arm)	0.639	0.361	0.000
M79.71 Fibromyalgia (Shoulder region)	0.639	0.361	0.000
H69 Other disorders of Eustachian tube	0.639	0.361	0.000
I42 Cardiomyopathy	0.639	0.361	0.000
S62.61 Fracture of other finger (open)	0.639	0.361	0.000
I87 Other disorders of veins	0.638	0.361	0.000
M82.1 Osteoporosis in endocrine disorders	0.638	0.362	0.000
E06.3 Autoimmune thyroiditis	0.000	0.362	0.638
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.635	0.365	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.635	0.365	0.000
S70-S79 Injuries to the hip and thigh	0.635	0.365	0.000
M79.5 Residual foreign body in soft tissue	0.634	0.366	0.000
T92.1 Sequelae of fracture of arm	0.633	0.366	0.000
E13 Other specified diabetes mellitus	0.000	0.367	0.633
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.633	0.367	0.000
S26 Injury of heart	0.633	0.367	0.000
S25 Injury of blood vessels of thorax	0.633	0.367	0.000
S24 Injury of nerves and spinal cord at thorax level	0.633	0.367	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.633	0.367	0.000
S21 Open wound of thorax	0.633	0.367	0.000
S32.4 Fracture of acetabulum	0.633	0.367	0.000
Y84.0 Cardiac catheterisation	0.632	0.368	0.000
M45-M49 Spondylopathies	0.631	0.369	0.000
H66 Suppurative and unspecified otitis media	0.631	0.369	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.630	0.370	0.000
H73.1 Chronic myringitis	0.630	0.370	0.000
H73.0 Acute myringitis	0.630	0.370	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.630	0.370	0.000
T90.1 Sequelae of open wound of head	0.629	0.371	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.371	0.629
I33 Acute and subacute endocarditis	0.628	0.372	0.000
S32.2 Fracture of coccyx	0.628	0.372	0.000
M90 Osteopathies in diseases classified elsewhere	0.627	0.373	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.627	0.373	0.000
M42 Spinal osteochondrosis	0.627	0.373	0.000
M40 Kyphosis and lordosis	0.627	0.373	0.000
N83.3 Acquired atrophy of ovary and Fallopian tube	0.626	0.373	0.000
T90.5 Sequelae of intracranial injury	0.626	0.374	0.000
S65 Injury of blood vessels at wrist and hand level	0.625	0.375	0.000
X60-X84 Intentional self-harm	0.625	0.375	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.625	0.375	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.625	0.375	0.000
H61.9 Disorder of external ear, unspecified	0.624	0.375	0.000
I12.9 Hypertensive renal disease without renal failure	0.624	0.376	0.000
M41.9 Scoliosis, unspecified	0.624	0.376	0.000
M50 Cervical disk disorders	0.623	0.376	0.000
M65-M68 Disorders of synovium and tendon	0.623	0.377	0.000
S67 Crushing injury of wrist and hand	0.623	0.377	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.623	0.377	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.377	0.623
E63 Other nutritional deficiencies	0.000	0.377	0.623
E56 Other vitamin deficiencies	0.000	0.377	0.623
E51 Thiamine deficiency	0.000	0.377	0.623
E50 Vitamin A deficiency	0.000	0.377	0.623
E60 Dietary zinc deficiency	0.000	0.377	0.623
E59 Dietary selenium deficiency	0.000	0.377	0.623
E58 Dietary calcium deficiency	0.000	0.377	0.623
E54 Ascorbic acid deficiency	0.000	0.377	0.623
E52 Niacin deficiency [pellagra]	0.000	0.377	0.623
M51.2 Other specified intervertebral disk displacement	0.623	0.377	0.000
N28.1 Cyst of kidney, acquired	0.623	0.377	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.622	0.378	0.000
N83.7 Haematoma of broad ligament	0.620	0.380	0.000
N83.6 Haematosalpinx	0.620	0.380	0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube	0.620	0.380	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.619	0.381	0.000
M89 Other disorders of bone	0.619	0.381	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.619	0.381	0.000
N85.1 Endometrial adenomatous hyperplasia	0.619	0.381	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.619	0.381	0.000
E61 Deficiency of other nutrient elements	0.000	0.382	0.617
N81.0 Female urethrocele	0.617	0.383	0.000
N10 Acute tubulo-interstitial nephritis	0.617	0.383	0.000
M43.1 Spondylolisthesis	0.617	0.383	0.000
Y59 Other and unspecified vaccines and biological substances	0.616	0.384	0.000
Y58 Bacterial vaccines	0.616	0.384	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.616	0.384	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.616	0.384	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.616	0.384	0.000
I81 Portal vein thrombosis	0.616	0.384	0.000
H61.0 Perichondritis of external ear	0.616	0.384	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.615	0.385	0.000
N39.2 Orthostatic proteinuria, unspecified	0.615	0.385	0.000
N39.1 Persistent proteinuria, unspecified	0.615	0.385	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.385	0.615
E34 Other endocrine disorders	0.000	0.385	0.615
E32 Diseases of thymus	0.000	0.385	0.615
E31 Polyglandular dysfunction	0.000	0.385	0.615
E30 Disorders of puberty, not elsewhere classified	0.000	0.385	0.615
E25 Adrenogenital disorders	0.000	0.385	0.615
E24 Cushing's syndrome	0.000	0.385	0.615
E20 Hypoparathyroidism	0.000	0.385	0.615
T90.8 Sequelae of other specified injuries of head	0.614	0.386	0.000
N45 Orchitis and epididymitis	0.614	0.386	0.000
I45 Other conduction disorders	0.614	0.386	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.614	0.386	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.614	0.386	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations