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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs41278851
log Bayes Factor = 11.6082
Chromosome 22   position 30,094,366  (GRCh37) Explore rs41278851 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.997 0.003 0.000
I20 Angina pectoris
0.996 0.004 0.000
Chapter II Neoplasms
0.993 0.007 0.000
Z86 Personal history of certain other diseases
0.992 0.008 0.000
I21 Acute myocardial infarction
0.992 0.008 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.990 0.010 0.000
Z86.4 Personal history of psychoactive substance abuse
0.989 0.011 0.000
I21.9 Acute myocardial infarction, unspecified
0.989 0.011 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.987 0.013 0.000
Chapter XXI Factors influencing health status and contact with health services
0.981 0.019 0.000
I25 Chronic ischaemic heart disease
0.981 0.019 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.977 0.023 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.976 0.024 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.974 0.026 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.973 0.027 0.000
M50-M54 Other dorsopathies
0.970 0.030 0.000
G90-G99 Other disorders of the nervous system
0.970 0.030 0.000
Chapter VII Diseases of the eye and adnexa
0.969 0.031 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.969 0.031 0.000
Z95.1 Presence of aortocoronary bypass graft
0.965 0.035 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.964 0.036 0.000
M54 Dorsalgia
0.964 0.036 0.000
I20.9 Angina pectoris, unspecified
0.963 0.037 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.962 0.038 0.000
I10-I15 Hypertensive diseases
0.956 0.044 0.000
Chapter I Certain infectious and parasitic diseases
0.951 0.049 0.000
C79 Secondary malignant neoplasm of other sites
0.951 0.049 0.000
I25.1 Atherosclerotic heart disease
0.949 0.051 0.000
C64-C68 Malignant neoplasms of urinary tract
0.948 0.052 0.000
I20.0 Unstable angina
0.946 0.054 0.000
M54.5 Low back pain
0.946 0.054 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.944 0.056 0.000
G40-G47 Episodic and paroxysmal disorders
0.940 0.060 0.000
I67 Other cerebrovascular diseases
0.940 0.060 0.000
M54.59 Low back pain (Site unspecified)
0.933 0.067 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.930 0.070 0.000
I24 Other acute ischaemic heart diseases
0.930 0.070 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.926 0.074 0.000
G81 Hemiplegia
0.922 0.078 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.918 0.082 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.916 0.084 0.000
I10 Essential (primary) hypertension
0.916 0.084 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.912 0.088 0.000
G47 Sleep disorders
0.906 0.094 0.000
C78.2 Secondary malignant neoplasm of pleura
0.905 0.095 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.899 0.101 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.893 0.107 0.000
G47.9 Sleep disorder, unspecified
0.889 0.111 0.000
C78.0 Secondary malignant neoplasm of lung
0.879 0.121 0.000
D00-D09 In situ neoplasms
0.876 0.124 0.000
G81.9 Hemiplegia, unspecified
0.874 0.126 0.000
M54.9 Dorsalgia, unspecified
0.871 0.128 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.871 0.129 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.867 0.133 0.000
I69 Sequelae of cerebrovascular disease
0.864 0.136 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.863 0.137 0.000
I67.8 Other specified cerebrovascular diseases
0.855 0.145 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.852 0.148 0.000
M54.3 Sciatica
0.851 0.149 0.000
I20.8 Other forms of angina pectoris
0.848 0.152 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.848 0.152 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.840 0.160 0.000
H04 Disorders of lachrymal system
0.834 0.166 0.000
A30-A49 Other bacterial diseases
0.832 0.168 0.000
Chapter XXII Codes for special purposes
0.832 0.168 0.000
B35-B49 Mycoses
0.830 0.170 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.829 0.171 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.828 0.172 0.000
Chapter X Diseases of the respiratory system
0.825 0.175 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.822 0.178 0.000
C67 Malignant neoplasm of bladder
0.821 0.179 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.820 0.180 0.000
G30-G32 Other degenerative diseases of the nervous system
0.819 0.181 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.816 0.184 0.000
Z80 Family history of malignant neoplasm
0.816 0.184 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.813 0.187 0.000
B07 Viral warts
0.812 0.188 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.811 0.189 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.807 0.192 0.000
I15 Secondary hypertension
0.803 0.197 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.799 0.201 0.000
Z81 Family history of mental and behavioural disorders
0.798 0.202 0.000
M53 Other dorsopathies, not elsewhere classified
0.797 0.203 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.797 0.203 0.000
C80 Malignant neoplasm without specification of site
0.796 0.204 0.000
H30-H36 Disorders of choroid and retina
0.792 0.208 0.000
I63 Cerebral infarction
0.789 0.211 0.000
C66 Malignant neoplasm of ureter
0.788 0.212 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.788 0.212 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.786 0.214 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.785 0.215 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.784 0.216 0.000
M50 Cervical disk disorders
0.783 0.216 0.000
I24.8 Other forms of acute ischaemic heart disease
0.782 0.218 0.000
D50-D53 Nutritional anaemias
0.782 0.218 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.782 0.218 0.000
I67.9 Cerebrovascular disease, unspecified
0.778 0.222 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.776 0.224 0.000
I25.5 Ischaemic cardiomyopathy
0.775 0.225 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.775 0.225 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.775 0.225 0.000
H46 Optic neuritis
0.773 0.227 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.773 0.227 0.000
G83 Other paralytic syndromes
0.772 0.228 0.000
I11 Hypertensive heart disease
0.772 0.228 0.000
G81.1 Spastic hemiplegia
0.772 0.228 0.000
J90-J94 Other diseases of pleura
0.772 0.228 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.769 0.231 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.766 0.234 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.765 0.235 0.000
G80 Infantile cerebral palsy
0.764 0.236 0.000
D50 Iron deficiency anaemia
0.764 0.236 0.000
G41 Status epilepticus
0.762 0.238 0.000
M91-M94 Chondropathies
0.762 0.238 0.000
M40-M43 Deforming dorsopathies
0.760 0.240 0.000
M54.50 Low back pain (Multiple sites in spine)
0.758 0.242 0.000
G91 Hydrocephalus
0.758 0.242 0.000
M60-M63 Disorders of muscles
0.758 0.242 0.000
I61 Intracerebral haemorrhage
0.756 0.243 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.756 0.244 0.000
G93 Other disorders of brain
0.752 0.248 0.000
M05-M14 Inflammatory polyarthropathies
0.752 0.248 0.000
C79.2 Secondary malignant neoplasm of skin
0.750 0.250 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.750 0.250 0.000
Q50-Q56 Congenital malformations of genital organs
0.749 0.251 0.000
C78.7 Secondary malignant neoplasm of liver
0.749 0.251 0.000
Q00-Q07 Congenital malformations of the nervous system
0.747 0.253 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.747 0.253 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.745 0.255 0.000
Q66 Congenital deformities of feet
0.744 0.256 0.000
D10-D36 Benign neoplasms
0.743 0.257 0.000
I67.2 Cerebral atherosclerosis
0.743 0.257 0.000
I21.4 Acute subendocardial myocardial infarction
0.743 0.257 0.000
H10-H13 Disorders of conjunctiva
0.741 0.259 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.741 0.259 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.740 0.260 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.738 0.262 0.000
I22 Subsequent myocardial infarction
0.738 0.262 0.000
B95-B98 Bacterial, viral and other infectious agents
0.737 0.263 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.737 0.263 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.735 0.265 0.000
G70-G73 Diseases of myoneural junction and muscle
0.735 0.265 0.000
M54.36 Sciatica (Lumbar region)
0.734 0.266 0.000
Z84 Family history of other conditions
0.734 0.266 0.000
C67.5 Bladder neck
0.734 0.266 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.733 0.267 0.000
D50.8 Other iron deficiency anaemias
0.732 0.268 0.000
I60 Subarachnoid haemorrhage
0.730 0.270 0.000
M80-M85 Disorders of bone density and structure
0.730 0.270 0.000
H04.1 Other disorders of lachrymal gland
0.730 0.270 0.000
O36 Maternal care for other known or suspected foetal problems
0.726 0.274 0.000
D09 Carcinoma in situ of other and unspecified sites
0.724 0.276 0.000
G43 Migraine
0.723 0.277 0.000
A41 Other septicaemia
0.723 0.277 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.722 0.278 0.000
O20 Haemorrhage in early pregnancy
0.722 0.278 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.722 0.278 0.000
H04.4 Chronic inflammation of lachrymal passages
0.721 0.279 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.719 0.281 0.000
H01 Other inflammation of eyelid
0.719 0.281 0.000
G90 Disorders of autonomic nervous system
0.718 0.282 0.000
C67.9 Bladder, unspecified
0.718 0.282 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I20.1 Angina pectoris with documented spasm
0.716 0.283 0.000
E00-E07 Disorders of thyroid gland
0.716 0.284 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.715 0.285 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.715 0.285 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.715 0.285 0.000
H05 Disorders of orbit
0.714 0.285 0.000
I62 Other nontraumatic intracranial haemorrhage
0.714 0.286 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.712 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.712 0.288 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.712 0.288 0.000
M54.57 Low back pain (Lumbosacral region)
0.712 0.288 0.000
Z12 Special screening examination for neoplasms
0.712 0.288 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.711 0.289 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.711 0.289 0.000
J93 Pneumothorax
0.711 0.289 0.000
H47.3 Other disorders of optic disk
0.711 0.289 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.710 0.290 0.000
H47.1 Papilloedema, unspecified
0.708 0.292 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.707 0.293 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.707 0.293 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.706 0.294 0.000
C65 Malignant neoplasm of renal pelvis
0.706 0.294 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.706 0.294 0.000
I25.6 Silent myocardial ischaemia
0.703 0.296 0.000
I25.4 Coronary artery aneurysm
0.703 0.296 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.703 0.296 0.000
B44 Aspergillosis
0.703 0.297 0.000
I63.9 Cerebral infarction, unspecified
0.702 0.298 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.701 0.299 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.700 0.300 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.700 0.300 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.700 0.300 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.699 0.301 0.000
H55-H59 Other disorders of eye and adnexa
0.698 0.302 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.698 0.302 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.698 0.302 0.000
H06.2 Dysthyroid exophthalmos
0.697 0.303 0.000
Z56 Problems related to employment and unemployment
0.696 0.304 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.695 0.305 0.000
G92 Toxic encephalopathy
0.695 0.305 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.693 0.307 0.000
B65-B83 Helminthiases
0.692 0.307 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.692 0.308 0.000
D12.6 Colon, unspecified
0.692 0.308 0.000
M54.8 Other dorsalgia
0.691 0.308 0.000
M54.0 Panniculitis affecting regions of neck and back
0.691 0.308 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.691 0.309 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.691 0.309 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.691 0.309 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.690 0.310 0.000
I15.9 Seconday hypertension, unspecified
0.690 0.310 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.688 0.312 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.687 0.313 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.687 0.313 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.686 0.314 0.000
M50.1 Cervical disk disorder with radiculopathy
0.686 0.314 0.000
D27 Benign neoplasm of ovary
0.686 0.314 0.000
I13 Hypertensive heart and renal disease
0.685 0.315 0.000
M54.4 Lumbago with sciatica
0.685 0.315 0.000
G96 Other disorders of central nervous system
0.685 0.315 0.000
B15-B19 Viral hepatitis
0.685 0.315 0.000
J95-J99 Other diseases of the respiratory system
0.684 0.316 0.000
M54.1 Radiculopathy
0.684 0.316 0.000
E03 Other hypothyroidism
0.683 0.317 0.000
Chapter XIV Diseases of the genitourinary system
0.682 0.318 0.000
B99-B99 Other infectious diseases
0.682 0.318 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.682 0.318 0.000
B50-B64 Protozoal diseases
0.682 0.318 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.682 0.318 0.000
A75-A79 Rickettsioses
0.682 0.318 0.000
A70-A74 Other diseases caused by chlamydiae
0.682 0.318 0.000
A65-A69 Other spirochaetal diseases
0.682 0.318 0.000
A20-A28 Certain zoonotic bacterial diseases
0.682 0.318 0.000
A15-A19 Tuberculosis
0.682 0.318 0.000
Z94 Transplanted organ and tissue status
0.682 0.318 0.000
C79.6 Secondary malignant neoplasm of ovary
0.682 0.318 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.682 0.318 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.682 0.318 0.000
M20-M25 Other joint disorders
0.681 0.319 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.680 0.320 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.680 0.320 0.000
M54.55 Low back pain (Thoracolumbar region)
0.678 0.321 0.000
M54.54 Low back pain-Thoracic
0.678 0.321 0.000
M54.53 Low back pain-Cervicothoracic
0.678 0.321 0.000
M54.52 Low back pain-Cervical
0.678 0.321 0.000
M54.51 Low back pain-Occipit-atl-axl
0.678 0.321 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.677 0.323 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.676 0.323 0.000
M06 Other rheumatoid arthritis
0.674 0.325 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.674 0.326 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.674 0.326 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.674 0.326 0.000
I67.5 Moyamoya disease
0.674 0.326 0.000
I67.4 Hypertensive encephalopathy
0.674 0.326 0.000
I67.3 Progressive vascular leukoencephalopathy
0.674 0.326 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.674 0.326 0.000
H34 Retinal vascular occlusions
0.673 0.327 0.000
M00-M03 Infectious arthropathies
0.672 0.328 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.671 0.329 0.000
H04.9 Disorder of lachrymal system, unspecified
0.669 0.331 0.000
B00 Herpesviral [herpes simplex] infections
0.669 0.331 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.669 0.331 0.000
Z81.8 Family history of other mental and behavioural disorders
0.669 0.331 0.000
Z89 Acquired absence of limb
0.668 0.332 0.000
A40 Streptococcal septicaemia
0.668 0.332 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.667 0.333 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.667 0.333 0.000
H35 Other retinal disorders
0.667 0.333 0.000
I24.1 Dressler's syndrome
0.667 0.333 0.000
C51-C58 Malignant neoplasms of female genital organs
0.666 0.333 0.000
B35 Dermatophytosis
0.666 0.334 0.000
O24 Diabetes mellitus in pregnancy
0.665 0.334 0.000
I25.3 Aneurysm of heart
0.664 0.335 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.664 0.336 0.000
Q35-Q37 Cleft lip and cleft palate
0.664 0.336 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.664 0.336 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.664 0.336 0.000
H25-H28 Disorders of lens
0.663 0.337 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.663 0.337 0.000
G81.0 Flaccid hemiplegia
0.661 0.339 0.000
H43-H45 Disorders of vitreous body and globe
0.660 0.340 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.659 0.341 0.000
Z95.3 Presence of xenogenic heart valve
0.659 0.341 0.000
N10-N16 Renal tubulo-interstitial diseases
0.659 0.341 0.000
G20-G26 Extrapyramidal and movement disorders
0.658 0.342 0.000
O36.5 Maternal care for poor foetal growth
0.658 0.342 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.657 0.343 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.655 0.345 0.000
A41.8 Other specified septicaemia
0.655 0.345 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.654 0.346 0.000
I67.1 Cerebral aneurysm, nonruptured
0.653 0.346 0.000
E03.9 Hypothyroidism, unspecified
0.653 0.347 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.652 0.348 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.651 0.349 0.000
D34 Benign neoplasm of thyroid gland
0.651 0.349 0.000
D55-D59 Haemolytic anaemias
0.650 0.350 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.650 0.350 0.000
D07.5 Prostate
0.650 0.350 0.000
G47.8 Other sleep disorders
0.649 0.351 0.000
G47.4 Narcolepsy and cataplexy
0.649 0.351 0.000
G47.2 Disorders of the sleep-wake schedule
0.649 0.351 0.000
Z93 Artificial opening status
0.649 0.351 0.000
M53.9 Dorsopathy, unspecified
0.648 0.352 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.648 0.352 0.000
M86-M90 Other osteopathies
0.648 0.352 0.000
Q66.8 Other congenital deformities of feet
0.648 0.352 0.000
Q80-Q89 Other congenital malformations
0.647 0.353 0.000
J93.9 Pneumothorax, unspecified
0.647 0.353 0.000
D60-D64 Aplastic and other anaemias
0.646 0.354 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.645 0.355 0.000
G93.8 Other specified disorders of brain
0.644 0.356 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.644 0.356 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.644 0.356 0.000
Chapter XX External causes of morbidity and mortality
0.643 0.357 0.000
D32 Benign neoplasm of meninges
0.642 0.358 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.642 0.358 0.000
D12.3 Transverse colon
0.641 0.359 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.640 0.360 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.639 0.361 0.000
A80-A89 Viral infections of the central nervous system
0.638 0.362 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.638 0.362 0.000
O23 Infections of genito-urinary tract in pregnancy
0.638 0.362 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.637 0.363 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.637 0.363 0.000
M54.6 Pain in thoracic spine
0.637 0.363 0.000
G83.4 Cauda equina syndrome
0.636 0.363 0.000
Q60-Q64 Congenital malformations of the urinary system
0.636 0.364 0.000
N20-N23 Urolithiasis
0.635 0.365 0.000
E20-E35 Disorders of other endocrine glands
0.635 0.365 0.000
O21 Excessive vomiting in pregnancy
0.634 0.366 0.000
A49 Bacterial infection of unspecified site
0.634 0.366 0.000
G41.9 Status epilepticus, unspecified
0.634 0.366 0.000
Z02 Examination and encounter for administrative purposes
0.633 0.366 0.000
J94 Other pleural conditions
0.633 0.367 0.000
O47 False labour
0.633 0.367 0.000
S50-S59 Injuries to the elbow and forearm
0.633 0.367 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.632 0.368 0.000
Q76 Congenital malformations of spine and bony thorax
0.631 0.369 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.629 0.370 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.629 0.371 0.000
G95 Other diseases of spinal cord
0.629 0.371 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.629 0.371 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.628 0.372 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.628 0.372 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.628 0.372 0.000
O28 Abnormal findings on antenatal screening of mother
0.626 0.373 0.000
M54.37 Sciatica (Lumbosacral region)
0.626 0.374 0.000
S90-S99 Injuries to the ankle and foot
0.626 0.374 0.000
M50.0 Cervical disk disorder with myelopathy
0.625 0.375 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.625 0.375 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.625 0.375 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.625 0.375 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.625 0.375 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.625 0.375 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.625 0.375 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.625 0.375 0.000
D03 Melanoma in situ
0.625 0.375 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.625 0.375 0.000
B06 Rubella [German measles]
0.625 0.375 0.000
B05 Measles
0.625 0.375 0.000
B01 Varicella [chickenpox]
0.625 0.375 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.625 0.375 0.000
B04 Monkeypox
0.625 0.375 0.000
B03 Smallpox
0.625 0.375 0.000
G80.9 Infantile cerebral palsy, unspecified
0.623 0.377 0.000
D05 Carcinoma in situ of breast
0.622 0.378 0.000
O85-O92 Complications predominantly related to the puerperium
0.621 0.379 0.000
H04.2 Epiphora
0.621 0.379 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.621 0.379 0.000
N13 Obstructive and reflux uropathy
0.621 0.379 0.000
J92 Pleural plaque
0.620 0.379 0.000
G94.1 Hydrocephalus in neoplastic disease
0.620 0.380 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.620 0.380 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.619 0.380 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.619 0.380 0.000
I78 Diseases of capillaries
0.620 0.380 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.619 0.381 0.000
C46 Kaposi's sarcoma
0.619 0.381 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.619 0.381 0.000
Z58 Problems related to physical environment
0.618 0.382 0.000
C80.9 Malignant neoplasm, unspecified
0.618 0.382 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.618 0.382 0.000
M54.2 Cervicalgia
0.618 0.382 0.000
O00-O08 Pregnancy with abortive outcome
0.616 0.384 0.000
G40 Epilepsy
0.616 0.384 0.000
M06.9 Rheumatoid arthritis, unspecified
0.616 0.384 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.615 0.385 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.614 0.385 0.000
D04 Carcinoma in situ of skin
0.614 0.386 0.000
D09.0 Bladder
0.614 0.386 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.614 0.386 0.000
N20 Calculus of kidney and ureter
0.614 0.386 0.000
H00 Hordeolum and chalazion
0.613 0.387 0.000
B44.1 Other pulmonary aspergillosis
0.612 0.388 0.000
Q66.3 Other congenital varus deformities of feet
0.611 0.389 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.611 0.389 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.610 0.389 0.000
M54.35 Sciatica (Thoracolumbar region)
0.610 0.390 0.000
M54.34 Sciatica-Thoracic
0.610 0.390 0.000
M54.33 Sciatica-Cervicothoracic
0.610 0.390 0.000
M54.32 Sciatica-Cervical
0.610 0.390 0.000
M54.31 Sciatica-Occipit-atl-axl
0.610 0.390 0.000
M54.30 Sciatica (Multiple sites in spine)
0.610 0.390 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.610 0.390 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.609 0.391 0.000
O80-O84 Delivery
0.608 0.392 0.000
C15-C26 Malignant neoplasms of digestive organs
0.608 0.392 0.000
H47.7 Disorder of visual pathways, unspecified
0.608 0.392 0.000
H47.6 Disorders of visual cortex
0.608 0.392 0.000
H47.5 Disorders of other visual pathways
0.608 0.392 0.000
H47.4 Disorders of optic chiasm
0.608 0.392 0.000
H47.2 Optic atrophy
0.608 0.392 0.000
G43.9 Migraine, unspecified
0.608 0.392 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.607 0.393 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.606 0.393 0.000
B37 Candidiasis
0.606 0.394 0.000
I74 Arterial embolism and thrombosis
0.606 0.394 0.000
G30 Alzheimer's disease
0.606 0.394 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.605 0.395 0.000
M41 Scoliosis
0.604 0.396 0.000
M62 Other disorders of muscle
0.602 0.398 0.000
I99 Other and unspecified disorders of circulatory system
0.601 0.399 0.000
K29 Gastritis and duodenitis
0.601 0.399 0.000
M54.56 Low back pain (Lumbar region)
0.601 0.399 0.000
Z60 Problems related to social environment
0.600 0.400 0.000
J81 Pulmonary oedema
0.600 0.400 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.599 0.401 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.599 0.401 0.000
H04.8 Other disorders of lachrymal system
0.598 0.402 0.000
H04.6 Other changes in lachrymal passages
0.598 0.402 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.598 0.402 0.000
H04.0 Dacryoadenitis
0.598 0.402 0.000
G82 Paraplegia and tetraplegia
0.598 0.402 0.000
M51 Other intervertebral disk disorders
0.597 0.402 0.000
A48 Other bacterial diseases, not elsewhere classified
0.597 0.403 0.000
A44 Bartonellosis
0.597 0.403 0.000
A43 Nocardiosis
0.597 0.403 0.000
A42 Actinomycosis
0.597 0.403 0.000
A39 Meningococcal infection
0.597 0.403 0.000
A37 Whooping cough
0.597 0.403 0.000
A36 Diphtheria
0.597 0.403 0.000
A32 Listeriosis
0.597 0.403 0.000
A31 Infection due to other mycobacteria
0.597 0.403 0.000
A30 Leprosy [Hansen's disease]
0.597 0.403 0.000
A38 Scarlet fever
0.597 0.403 0.000
A35 Other tetanus
0.597 0.403 0.000
A34 Obstetrical tetanus
0.597 0.403 0.000
A33 Tetanus neonatorum
0.597 0.403 0.000
K29.8 Duodenitis
0.596 0.404 0.000
M92 Other juvenile osteochondrosis
0.595 0.405 0.000
B48 Other mycoses, not elsewhere classified
0.595 0.405 0.000
B47 Mycetoma
0.595 0.405 0.000
B46 Zygomycosis
0.595 0.405 0.000
B45 Cryptococcosis
0.595 0.405 0.000
B43 Chromomycosis and phaeomycotic abscess
0.595 0.405 0.000
B42 Sporotrichosis
0.595 0.405 0.000
B41 Paracoccidioidomycosis
0.595 0.405 0.000
B40 Blastomycosis
0.595 0.405 0.000
B39 Histoplasmosis
0.595 0.405 0.000
B38 Coccidioidomycosis
0.595 0.405 0.000
B36 Other superficial mycoses
0.595 0.405 0.000
Chapter XI Diseases of the digestive system
0.595 0.405 0.000
J40-J47 Chronic lower respiratory diseases
0.594 0.406 0.000
H11 Other disorders of conjunctiva
0.594 0.406 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.593 0.406 0.000
Q78 Other osteochondrodysplasias
0.593 0.406 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.593 0.406 0.000
Q75 Other congenital malformations of skull and face bones
0.593 0.406 0.000
Q74 Other congenital malformations of limb(s)
0.593 0.406 0.000
Q73 Reduction defects of unspecified limb
0.593 0.406 0.000
Q72 Reduction defects of lower limb
0.593 0.406 0.000
Q71 Reduction defects of upper limb
0.593 0.406 0.000
Q70 Syndactyly
0.593 0.406 0.000
Q69 Polydactyly
0.593 0.406 0.000
Q68 Other congenital musculoskeletal deformities
0.593 0.406 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.593 0.406 0.000
Q65 Congenital deformities of hip
0.593 0.406 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.593 0.407 0.000
D06 Carcinoma in situ of cervix uteri
0.593 0.407 0.000
M85 Other disorders of bone density and structure
0.593 0.407 0.000
E50-E64 Other nutritional deficiencies
0.592 0.407 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.592 0.408 0.000
K29.5 Chronic gastritis, unspecified
0.591 0.409 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.591 0.409 0.000
M65-M68 Disorders of synovium and tendon
0.590 0.409 0.000
M24 Other specific joint derangements
0.590 0.409 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.590 0.410 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.589 0.411 0.000
B49 Unspecified mycosis
0.589 0.411 0.000
C67.8 Overlapping lesion of bladder
0.588 0.411 0.000
C67.7 Urachus
0.588 0.411 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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