TreeWAS – Variant ID: rs4149433

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter II Neoplasms	1.000	0.000
# Top node	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
D10-D36 Benign neoplasms	0.997	0.003
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.995	0.005
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.992	0.008
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.992	0.008
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.990	0.010
Z40-Z54 Persons encountering health services for specific procedures and health care	0.988	0.012
Z85 Personal history of malignant neoplasm	0.985	0.015
Chapter XV Pregnancy, childbirth and the puerperium	0.983	0.017
C50-C50 Malignant neoplasm of breast	0.977	0.023
Z85.3 Personal history of malignant neoplasm of breast	0.976	0.024
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.970	0.030
Chapter XII Diseases of the skin and subcutaneous tissue	0.970	0.030
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.969	0.031
C50 Malignant neoplasm of breast	0.961	0.039
Chapter IV Endocrine, nutritional and metabolic diseases	0.949	0.051
Z51 Other medical care	0.947	0.053
C50.9 Breast, unspecified	0.944	0.056
Z37 Outcome of delivery	0.943	0.057
Chapter XIV Diseases of the genitourinary system	0.933	0.067
S00-S09 Injuries to the head	0.931	0.069
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.927	0.073
Z37.0 Single live birth	0.923	0.077
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.914	0.086
C79 Secondary malignant neoplasm of other sites	0.908	0.092
E70-E90 Metabolic disorders	0.907	0.093
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.906	0.094
C78.7 Secondary malignant neoplasm of liver	0.900	0.100
Z90 Acquired absence of organs, not elsewhere classified	0.895	0.105
L60-L75 Disorders of skin appendages	0.892	0.108
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.891	0.109
D12.4 Descending colon	0.890	0.110
N80-N98 Noninflammatory disorders of female genital tract	0.882	0.118
D12.0 Caecum	0.878	0.122
C78.0 Secondary malignant neoplasm of lung	0.873	0.127
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.866	0.134
Z51.1 Chemotherapy session for neoplasm	0.863	0.137
Z51.5 Palliative care	0.861	0.139
Chapter XX External causes of morbidity and mortality	0.857	0.143
L80-L99 Other disorders of the skin and subcutaneous tissue	0.852	0.148
D12.5 Sigmoid colon	0.848	0.152
E87 Other disorders of fluid, electrolyte and acid-base balance	0.847	0.153
O20-O29 Other maternal disorders predominantly related to pregnancy	0.847	0.153
Z42 Follow-up care involving plastic surgery	0.844	0.156
L72 Follicular cysts of skin and subcutaneous tissue	0.836	0.164
D25 Leiomyoma of uterus	0.835	0.165
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.833	0.167
Z88.6 Personal history of allergy to analgesic agent	0.831	0.169
D23 Other benign neoplasms of skin	0.829	0.171
O60-O75 Complications of labour and delivery	0.828	0.172
D12.6 Colon, unspecified	0.827	0.173
Z51.0 Radiotherapy session	0.827	0.173
Z45 Adjustment and management of implanted device	0.824	0.176
M45-M49 Spondylopathies	0.822	0.178
Z90.1 Acquired absence of breast(s)	0.820	0.180
Chapter X Diseases of the respiratory system	0.820	0.180
T81 Complications of procedures, not elsewhere classified	0.818	0.182
N60-N64 Disorders of breast	0.814	0.186
D12.2 Ascending colon	0.812	0.188
Z80 Family history of malignant neoplasm	0.812	0.188
E86 Volume depletion	0.808	0.192
S60-S69 Injuries to the wrist and hand	0.808	0.192
Chapter V Mental and behavioural disorders	0.808	0.192
O36 Maternal care for other known or suspected foetal problems	0.806	0.194
D17 Benign lipomatous neoplasm	0.806	0.194
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.804	0.196
L00-L08 Infections of the skin and subcutaneous tissue	0.804	0.196
S01 Open wound of head	0.802	0.198
T36-T50 Poisoning by drugs, medicaments and biological substances	0.798	0.202
C15-C26 Malignant neoplasms of digestive organs	0.797	0.203
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.789	0.211
Z98 Other postsurgical states	0.785	0.215
D24 Benign neoplasm of breast	0.784	0.216
S09 Other and unspecified injuries of head	0.783	0.217
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.778	0.221
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.777	0.223
Z46 Fitting and adjustment of other devices	0.775	0.225
C50.4 Upper-outer quadrant of breast	0.774	0.226
S00 Superficial injury of head	0.773	0.227
O00-O08 Pregnancy with abortive outcome	0.773	0.227
L72.1 Trichilemmal cyst	0.773	0.227
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.772	0.228
N89 Other noninflammatory disorders of vagina	0.769	0.231
S40-S49 Injuries to the shoulder and upper arm	0.768	0.232
D12.3 Transverse colon	0.766	0.234
O94-O99 Other obstetric conditions, not elsewhere classified	0.765	0.235
L97 Ulcer of lower limb, not elsewhere classified	0.760	0.240
Z94 Transplanted organ and tissue status	0.759	0.241
N10-N16 Renal tubulo-interstitial diseases	0.758	0.242
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.756	0.244
M70-M79 Other soft tissue disorders	0.755	0.245
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.755	0.245
Z35 Supervision of high-risk pregnancy	0.753	0.247
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.752	0.248
M47 Spondylosis	0.751	0.249
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.750	0.250
Z47 Other orthopaedic follow-up care	0.749	0.251
E10-E14 Diabetes mellitus	0.747	0.253
Chapter VI Diseases of the nervous system	0.746	0.254
D36 Benign neoplasm of other and unspecified sites	0.745	0.255
C51-C58 Malignant neoplasms of female genital organs	0.744	0.256
Z42.1 Follow-up care involving plastic surgery of breast	0.742	0.258
D00-D09 In situ neoplasms	0.742	0.258
S20-S29 Injuries to the thorax	0.742	0.258
Z34 Supervision of normal pregnancy	0.740	0.260
Z83 Family history of other specific disorders	0.737	0.263
Z53 Persons encountering health services for specifie procedures, not carried out	0.734	0.266
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.733	0.267
Z41 Procedures for purposes other than remedying health state	0.733	0.267
Z93 Artificial opening status	0.732	0.268
S80-S89 Injuries to the knee and lower leg	0.730	0.270
N17-N19 Renal failure	0.730	0.270
O36.8 Maternal care for other specified foetal problems	0.730	0.270
E87.6 Hypokalaemia	0.729	0.271
Z36 Antenatal screening	0.729	0.271
T85 Complications of other internal prosthetic devices, implants and grafts	0.728	0.272
L72.0 Epidermal cyst	0.728	0.272
N85 Other noninflammatory disorders of uterus, except cervix	0.724	0.276
M05-M14 Inflammatory polyarthropathies	0.724	0.276
J09-J18 Influenza and pneumonia	0.723	0.277
D12.8 Rectum	0.722	0.278
O48 Prolonged pregnancy	0.721	0.279
Z40 Prophylactic surgery	0.719	0.281
Z85.4 Personal history of malignant neoplasm of genital organs	0.719	0.281
O34 Maternal care for known or suspected abnormality of pelvic organs	0.718	0.282
D37-D48 Neoplasms of uncertain or unknown behaviour	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.717	0.283
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.717	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.717	0.283
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.717	0.283
S70-S79 Injuries to the hip and thigh	0.716	0.283
L20-L30 Dermatitis and eczema	0.716	0.284
D35 Benign neoplasm of other and unspecified endocrine glands	0.715	0.285
D33 Benign neoplasm of brain and other parts of central nervous system	0.715	0.285
D32 Benign neoplasm of meninges	0.715	0.285
D31 Benign neoplasm of eye and adnexa	0.715	0.285
D30 Benign neoplasm of urinary organs	0.715	0.285
D29 Benign neoplasm of male genital organs	0.715	0.285
D28 Benign neoplasm of other and unspecified female genital organs	0.715	0.285
D26 Other benign neoplasms of uterus	0.715	0.285
D21 Other benign neoplasms of connective and other soft tissue	0.715	0.285
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.715	0.285
D19 Benign neoplasm of mesothelial tissue	0.715	0.285
D16 Benign neoplasm of bone and articular cartilage	0.715	0.285
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.715	0.285
D14 Benign neoplasm of middle ear and respiratory system	0.715	0.285
D11 Benign neoplasm of major salivary glands	0.715	0.285
D10 Benign neoplasm of mouth and pharynx	0.715	0.285
D34 Benign neoplasm of thyroid gland	0.715	0.285
O26 Maternal care for other conditions predominantly related to pregnancy	0.715	0.285
C80 Malignant neoplasm without specification of site	0.713	0.287
C76 Malignant neoplasm of other and ill-defined sites	0.713	0.287
Z90.3 Acquired absence of part of stomach	0.713	0.287
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.713	0.287
Z51.3 Blood transfusion without reported diagnosis	0.712	0.288
E87.2 Acidosis	0.712	0.288
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.711	0.289
T79-T79 Certain early complications of trauma	0.711	0.289
T66-T78 Other and unspecified effects of external causes	0.711	0.289
T33-T35 Frostbite	0.711	0.289
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.711	0.289
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289
T20-T25 Burns and corrosions of external body surface, specified by site	0.711	0.289
T15-T19 Effects of foreign body entering through natural orifice	0.711	0.289
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.711	0.289
T00-T07 Injuries involving multiple body regions	0.711	0.289
S90-S99 Injuries to the ankle and foot	0.711	0.289
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.711	0.289
S10-S19 Injuries to the neck	0.711	0.289
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.711	0.289
Z97 Presence of other devices	0.711	0.289
Z89 Acquired absence of limb	0.711	0.289
Z84 Family history of other conditions	0.711	0.289
Z81 Family history of mental and behavioural disorders	0.711	0.289
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.710	0.289
J00-J06 Acute upper respiratory infections	0.710	0.290
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.710	0.290
D12.9 Anus and anal canal	0.709	0.290
D12.7 Rectosigmoid junction	0.709	0.290
D12.1 Appendix	0.709	0.290
D27 Benign neoplasm of ovary	0.709	0.290
Chapter I Certain infectious and parasitic diseases	0.709	0.291
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.708	0.292
Z54 Convalescence	0.708	0.292
Z52 Donors of organs and tissues	0.708	0.292
Z49 Care involving dialysis	0.708	0.292
Z48 Other surgical follow-up care	0.708	0.292
Z44 Fitting and adjustment of external prosthetic device	0.708	0.292
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.707	0.293
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.707	0.293
Z85.0 Personal history of malignant neoplasm of digestive organs	0.706	0.294
Z85.9 Personal history of malignant neoplasm, unspecified	0.706	0.294
Z85.6 Personal history of leukaemia	0.706	0.294
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.706	0.294
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.706	0.294
S50-S59 Injuries to the elbow and forearm	0.706	0.294
O85-O92 Complications predominantly related to the puerperium	0.705	0.295
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.705	0.295
O42 Premature rupture of membranes	0.704	0.296
Z88.1 Personal history of allergy to other antibiotic agents	0.703	0.297
M47.8 Other spondylosis	0.701	0.299
N90 Other noninflammatory disorders of vulva and perineum	0.700	0.300
N60 Benign mammary dysplasia	0.697	0.303
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.696	0.304
N84 Polyp of female genital tract	0.696	0.304
Z39 Postpartum care and examination	0.696	0.304
Z38 Liveborn infants according to place of birth	0.696	0.304
Z32 Pregnancy examination and test	0.696	0.304
Z31 Procreative management	0.696	0.304
Z33 Pregnant state, incidental	0.696	0.304
L50-L54 Urticaria and erythema	0.695	0.305
L10-L14 Bullous disorders	0.695	0.305
O72 Postpartum haemorrhage	0.695	0.305
Chapter VIII Diseases of the ear and mastoid process	0.694	0.305
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.694	0.305
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.694	0.305
C78.4 Secondary malignant neoplasm of small intestine	0.694	0.305
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.694	0.305
C78.2 Secondary malignant neoplasm of pleura	0.694	0.305
C78.1 Secondary malignant neoplasm of mediastinum	0.694	0.305
Z45.0 Adjustment and management of cardiac pacemaker	0.693	0.307
N70-N77 Inflammatory diseases of female pelvic organs	0.691	0.309
Z53.0 Procedure not carried out because of contraindication	0.691	0.309
D25.0 Submucous leiomyoma of uterus	0.690	0.310
Z88.2 Personal history of allergy to sulphonamides	0.689	0.310
E83 Disorders of mineral metabolism	0.689	0.311
C50.8 Overlapping lesion of breast	0.689	0.311
C50.6 Axillary tail of breast	0.689	0.311
C50.5 Lower-outer quadrant of breast	0.689	0.311
C50.3 Lower-inner quadrant of breast	0.689	0.311
C50.2 Upper-inner quadrant of breast	0.689	0.311
C50.1 Central portion of breast	0.689	0.311
C50.0 Nipple and areola	0.689	0.311
C18 Malignant neoplasm of colon	0.689	0.311
N89.8 Other specified noninflammatory disorders of vagina	0.687	0.312
O80-O84 Delivery	0.687	0.313
C77.5 Intrapelvic lymph nodes	0.687	0.313
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.686	0.314
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.685	0.315
C77.1 Intrathoracic lymph nodes	0.683	0.317
E50-E64 Other nutritional deficiencies	0.683	0.317
E40-E46 Malnutrition	0.681	0.319
E20-E35 Disorders of other endocrine glands	0.681	0.319
E14 Unspecified diabetes mellitus	0.679	0.321
L40-L45 Papulosquamous disorders	0.679	0.321
S01.1 Open wound of eyelid and periocular area	0.679	0.321
Z51.9 Medical care, unspecified	0.679	0.321
Z51.8 Other specified medical care	0.679	0.321
Z51.6 Desensitisation to allergens	0.679	0.321
Z43 Attention to artificial openings	0.679	0.321
M40-M43 Deforming dorsopathies	0.678	0.322
S09.9 Unspecified injury of head	0.677	0.323
D18 Haemangioma and lymphangioma, any site	0.676	0.324
Z37.9 Outcome of delivery unspecified	0.676	0.324
Z37.7 Other multiple births, all stillborn	0.676	0.324
Z37.6 Other multiple births, some liveborn	0.676	0.324
Z37.5 Other multiple births, all liveborn	0.676	0.324
Z37.4 Twins, both stillborn	0.676	0.324
Z37.3 Twins, one liveborn and one stillborn	0.676	0.324
Z37.2 Twins, both liveborn	0.676	0.324
Z37.1 Single stillbirth	0.676	0.324
C64-C68 Malignant neoplasms of urinary tract	0.674	0.326
Z98.8 Other specified postsurgical states	0.672	0.328
O20 Haemorrhage in early pregnancy	0.670	0.330
O68 Labour and delivery complicated by foetal stress [distress]	0.669	0.331
Z90.5 Acquired absence of kidney	0.669	0.331
N99-N99 Other disorders of the genitourinary system	0.669	0.331
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.668	0.332
S08 Traumatic amputation of part of head	0.668	0.332
S07 Crushing injury of head	0.668	0.332
S06 Intracranial injury	0.668	0.332
S05 Injury of eye and orbit	0.668	0.332
S04 Injury of cranial nerves	0.668	0.332
S03 Dislocation, sprain and strain of joints and ligaments of head	0.668	0.332
S02 Fracture of skull and facial bones	0.668	0.332
C77.3 Axillary and upper limb lymph nodes	0.667	0.333
E87.1 Hypo-osmolality and hyponatraemia	0.666	0.334
N95 Menopausal and other perimenopausal disorders	0.665	0.335
Z88.7 Personal history of allergy to serum and vaccine	0.665	0.335
Z88.4 Personal history of allergy to anaesthetic agent	0.665	0.335
Z88.3 Personal history of allergy to other anti-infective agents	0.665	0.335
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.665	0.335
N87 Dysplasia of cervix uteri	0.664	0.336
L02 Cutaneous abscess, furuncle and carbuncle	0.663	0.337
Z96 Presence of other functional implants	0.663	0.337
Z80.3 Family history of malignant neoplasm of breast	0.662	0.338
C79.8 Secondary malignant neoplasm of other specified sites	0.661	0.339
Z80.4 Family history of malignant neoplasm of genital organs	0.659	0.341
M79 Other soft tissue disorders, not elsewhere classified	0.659	0.341
M48 Other spondylopathies	0.658	0.342
Z00-Z13 Persons encountering health services for examination and investigation	0.657	0.343
C43-C44 Melanoma and other malignant neoplasms of skin	0.656	0.343
C77.2 Intra-abdominal lymph nodes	0.655	0.344
O47 False labour	0.655	0.345
O46 Antepartum haemorrhage, not elsewhere classified	0.655	0.345
O45 Premature separation of placenta [abruptio placentae]	0.655	0.345
O44 Placenta praevia	0.655	0.345
O43 Placental disorders	0.655	0.345
O41 Other disorders of amniotic fluid and membranes	0.655	0.345
O35 Maternal care for known or suspected foetal abnormality and damage	0.655	0.345
O33 Maternal care for known or suspected disproportion	0.655	0.345
O31 Complications specific to multiple gestation	0.655	0.345
O30 Multiple gestation	0.655	0.345
O40 Polyhydramnios	0.655	0.345
Z85.5 Personal history of malignant neoplasm of urinary tract	0.654	0.346
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.654	0.346
J18 Pneumonia, organism unspecified	0.653	0.347
O32 Maternal care for known or suspected malpresentation of foetus	0.653	0.347
E65-E68 Obesity and other hyperalimentation	0.653	0.347
N61 Inflammatory disorders of breast	0.653	0.347
Z88.5 Personal history of allergy to narcotic agent	0.652	0.348
N00-N08 Glomerular diseases	0.651	0.349
N30-N39 Other diseases of urinary system	0.651	0.349
C60-C63 Malignant neoplasms of male genital organs	0.651	0.349
D25.1 Intramural leiomyoma of uterus	0.651	0.349
C79.9 Secondary malignant neoplasm, unspecified site	0.651	0.349
C79.7 Secondary malignant neoplasm of adrenal gland	0.651	0.349
C79.6 Secondary malignant neoplasm of ovary	0.651	0.349
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.651	0.349
C79.2 Secondary malignant neoplasm of skin	0.651	0.349
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.651	0.349
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.651	0.349
E88 Other metabolic disorders	0.650	0.350
E85 Amyloidosis	0.650	0.350
E84 Cystic fibrosis	0.650	0.350
E80 Disorders of porphyrin and bilirubin metabolism	0.650	0.350
E79 Disorders of purine and pyrimidine metabolism	0.650	0.350
E77 Disorders of glycoprotein metabolism	0.650	0.350
E76 Disorders of glycosaminoglycan metabolism	0.650	0.350
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.650	0.350
E74 Other disorders of carbohydrate metabolism	0.650	0.350
E73 Lactose intolerance	0.650	0.350
E72 Other disorders of amino-acid metabolism	0.650	0.350
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.650	0.350
E70 Disorders of aromatic amino-acid metabolism	0.650	0.350
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.650	0.350
T88 Other complications of surgical and medical care, not elsewhere classified	0.649	0.351
T87 Complications peculiar to reattachment and amputation	0.649	0.351
T86 Failure and rejection of transplanted organs and tissues	0.649	0.351
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.649	0.351
T80 Complications following infusion, transfusion and therapeutic injection	0.649	0.351
Z45.8 Adjustment and management of other implanted devices	0.648	0.352
L82 Seborrhoeic keratosis	0.647	0.353
D22 Melanocytic naevi	0.644	0.356
E87.5 Hyperkalaemia	0.644	0.356
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.642	0.358
S62 Fracture at wrist and hand level	0.642	0.358
Z90.8 Acquired absence of other organs	0.642	0.358
Z90.6 Acquired absence of other parts of urinary tract	0.642	0.358
Z90.2 Acquired absence of lung [part of]	0.642	0.358
Z90.0 Acquired absence of part of head and neck	0.642	0.358
T81.8 Other complications of procedures, not elsewhere classified	0.641	0.359
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.641	0.359
N13 Obstructive and reflux uropathy	0.641	0.359
D23.5 Skin of trunk	0.639	0.360
L75 Apocrine sweat disorders	0.639	0.361
L74 Eccrine sweat disorders	0.639	0.361
L73 Other follicular disorders	0.639	0.361
L71 Rosacea	0.639	0.361
L70 Acne	0.639	0.361
L68 Hypertrichosis	0.639	0.361
L67 Hair colour and hair shaft abnormalities	0.639	0.361
L66 Cicatricial alopecia [scarring hair loss]	0.639	0.361
L65 Other nonscarring hair loss	0.639	0.361
L64 Androgenic alopecia	0.639	0.361
L63 Alopecia areata	0.639	0.361
L62 Nail disorders in diseases classified elsewhere	0.639	0.361
L60 Nail disorders	0.639	0.361
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.639	0.361
M91-M94 Chondropathies	0.639	0.361
M86-M90 Other osteopathies	0.639	0.361
M60-M63 Disorders of muscles	0.639	0.361
M00-M03 Infectious arthropathies	0.639	0.361
N97 Female infertility	0.637	0.363
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.636	0.363
D25.2 Subserosal leiomyoma of uterus	0.636	0.364
Z90.7 Acquired absence of genital organ(s)	0.635	0.364
D23.3 Skin of other and unspecified parts of face	0.635	0.365
S00.8 Superficial injury of other parts of head	0.633	0.367
Z95 Presence of cardiac and vascular implants and grafts	0.633	0.367
N98 Complications associated with artificial fertilisation	0.632	0.368
N91 Absent, scanty and rare menstruation	0.632	0.368
N88 Other noninflammatory disorders of cervix uteri	0.632	0.368
N82 Fistulae involving female genital tract	0.632	0.368
N96 Habitual aborter	0.632	0.368
E14.9 Without complications	0.631	0.369
S01.0 Open wound of scalp	0.630	0.370
Z50 Care involving use of rehabilitation procedures	0.629	0.370
Chapter VII Diseases of the eye and adnexa	0.629	0.371
N86 Erosion and ectropion of cervix uteri	0.628	0.372
D23.6 Skin of upper limb, including shoulder	0.627	0.373
N85.8 Other specified noninflammatory disorders of uterus	0.627	0.373
O04 Medical abortion	0.627	0.373
S61 Open wound of wrist and hand	0.626	0.374
M13 Other arthritis	0.625	0.375
M65-M68 Disorders of synovium and tendon	0.624	0.376
N25-N29 Other disorders of kidney and ureter	0.622	0.377
Z46.6 Fitting and adjustment of urinary device	0.622	0.377
N93 Other abnormal uterine and vaginal bleeding	0.622	0.378
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.621	0.379
C77.9 Lymph node, unspecified	0.621	0.379
C77.8 Lymph nodes of multiple regions	0.621	0.379
C77.4 Inguinal and lower limb lymph nodes	0.621	0.379
C77.0 Lymph nodes of head, face and neck	0.621	0.379
O26.8 Other specified pregnancy-related conditions	0.620	0.380
C34 Malignant neoplasm of bronchus and lung	0.620	0.380
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.619	0.381
L90 Atrophic disorders of skin	0.618	0.382
D23.1 Skin of eyelid, including canthus	0.616	0.383
J20-J22 Other acute lower respiratory infections	0.616	0.384
F00-F09 Organic, including symptomatic, mental disorders	0.616	0.384
M50-M54 Other dorsopathies	0.616	0.384
C18.7 Sigmoid colon	0.616	0.384
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.614	0.386
Y60-Y69 Misadventures to patients during surgical and medical care	0.614	0.386
Y35-Y36 Legal intervention and operations of war	0.614	0.386
Y10-Y34 Event of undetermined intent	0.614	0.386
Y00-Y09 Assault	0.614	0.386
X85-X99 Assault	0.614	0.386
X60-X84 Intentional self-harm	0.614	0.386
X58-X59 Accidental exposure to other and unspecified factors	0.614	0.386
X50-X57 Overexertion, travel and privation	0.614	0.386
X40-X49 Accidental poisoning by and exposure to noxious substances	0.614	0.386
X30-X39 Exposure to forces of nature	0.614	0.386
X20-X29 Contact with venomous animals and plants	0.614	0.386
X10-X19 Contact with heat and hot substances	0.614	0.386
X00-X09 Exposure to smoke, fire and flames	0.614	0.386
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.614	0.386
W75-W84 Other accidental threats to breathing	0.614	0.386
W65-W74 Accidental drowning and submersion	0.614	0.386
W50-W64 Exposure to animate mechanical forces	0.614	0.386
W20-W49 Exposure to inanimate mechanical forces	0.614	0.386
V98-V99 Other and unspecified transport accidents	0.614	0.386
V95-V97 Air and space transport accidents	0.614	0.386
V90-V94 Water transport accidents	0.614	0.386
V80-V89 Other land transport accidents	0.614	0.386
V70-V79 Bus occupant injured in transport accident	0.614	0.386
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.614	0.386
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.614	0.386
V40-V49 Car occupant injured in transport accident	0.614	0.386
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.614	0.386
V20-V29 Motorcycle rider injured in transport accident	0.614	0.386
V10-V19 Pedal cyclist injured in transport accident	0.614	0.386
V01-V09 Pedestrian injured in transport accident	0.614	0.386
L03 Cellulitis	0.613	0.387
N60.2 Fibroadenosis of breast	0.613	0.387
E16 Other disorders of pancreatic internal secretion	0.611	0.389
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.611	0.389
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.611	0.389
L95 Vasculitis limited to skin, not elsewhere classified	0.611	0.389
L94 Other localised connective tissue disorders	0.611	0.389
L93 Lupus erythematosus	0.611	0.389
L92 Granulomatous disorders of skin and subcutaneous tissue	0.611	0.389
L89 Decubitus ulcer	0.611	0.389
L87 Transepidermal elimination disorders	0.611	0.389
L85 Other epidermal thickening	0.611	0.389
L81 Other disorders of pigmentation	0.611	0.389
L88 Pyoderma gangrenosum	0.611	0.389
L86 Keratoderma in diseases classified elsewhere	0.611	0.389
L84 Corns and callosities	0.611	0.389
L83 Acanthosis nigricans	0.611	0.389
L80 Vitiligo	0.611	0.389
Z87 Personal history of other diseases and conditions	0.610	0.390
O70 Perineal laceration during delivery	0.610	0.390
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.609	0.391
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.609	0.391
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.607	0.392
E87.7 Fluid overload	0.607	0.392
E87.4 Mixed disorder of acid-base balance	0.607	0.392
E87.3 Alkalosis	0.607	0.392
E87.0 Hyperosmolality and hypernatraemia	0.607	0.392
O29 Complications of anaesthesia during pregnancy	0.607	0.393
O28 Abnormal findings on antenatal screening of mother	0.607	0.393
O24 Diabetes mellitus in pregnancy	0.607	0.393
O23 Infections of genito-urinary tract in pregnancy	0.607	0.393
O22 Venous complications in pregnancy	0.607	0.393
O21 Excessive vomiting in pregnancy	0.607	0.393
O25 Malnutrition in pregnancy	0.607	0.393
Z51.4 Preparatory care for treatment, not elsewhere classified	0.606	0.394
Z30 Contraceptive management	0.606	0.394
Z42.9 Follow-up care involving plastic surgery, unspecified	0.605	0.394
Z42.8 Follow-up care involving plastic surgery of other body part	0.605	0.394
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.605	0.394
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.605	0.394
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.605	0.394
Z42.0 Follow-up care involving plastic surgery of head and neck	0.605	0.394
L91 Hypertrophic disorders of skin	0.604	0.396
M47.82 Other spondylosis (Cervical region)	0.602	0.398
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.601	0.399
T81.3 Disruption of operation wound, not elsewhere classified	0.600	0.399
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.599	0.401
L72.2 Steatocystoma multiplex	0.599	0.401

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations