TreeWAS – Variant ID: rs4253399

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I26.9 Pulmonary embolism without mention of acute cor pulmonale	1.000	0.000	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	1.000	0.000	0.000
Z86.7 Personal history of diseases of the circulatory system	1.000	0.000	0.000
Z92.1 Personal history of long-term (current) use of anticoagulants	0.998	0.002	0.000
I80 Phlebitis and thrombophlebitis	0.870	0.130	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.865	0.135	0.000
I26 Pulmonary embolism	0.782	0.218	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.659	0.341	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.646	0.354	0.000
I27 Other pulmonary heart diseases	0.632	0.368	0.000
I27.0 Primary pulmonary hypertension	0.578	0.422	0.000
I27.9 Pulmonary heart disease, unspecified	0.573	0.427	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.519	0.481	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.502	0.498	0.000
I27.2 Other secondary pulmonary hypertension	0.456	0.544	0.000
I27.1 Kyphoscoliotic heart disease	0.453	0.547	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.434	0.566	0.000
I27.8 Other specified pulmonary heart diseases	0.433	0.567	0.000
I28 Other diseases of pulmonary vessels	0.411	0.589	0.000
I44.2 Atrioventricular block, complete	0.306	0.694	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.298	0.702	0.000
I44.0 Atrioventricular block, first degree	0.298	0.702	0.000
I28.1 Aneurysm of pulmonary artery	0.294	0.705	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.294	0.705	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.293	0.706	0.000
I44 Atrioventricular and left bundle-branch block	0.292	0.708	0.000
I44.3 Other and unspecified atrioventricular block	0.228	0.772	0.000
I28.8 Other specified diseases of pulmonary vessels	0.227	0.773	0.000
I30 Acute pericarditis	0.215	0.785	0.000
I44.6 Other and unspecified fascicular block	0.215	0.785	0.000
I30-I52 Other forms of heart disease	0.213	0.787	0.000
I30.9 Acute pericarditis, unspecified	0.213	0.787	0.000
Chapter IX Diseases of the circulatory system	0.211	0.789	0.000
I44.5 Left posterior fascicular block	0.210	0.790	0.000
E10.3 With ophthalmic complications	0.205	0.795	0.000
I34 Nonrheumatic mitral valve disorders	0.203	0.797	0.000
I34.0 Mitral (valve) insufficiency	0.198	0.802	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.198	0.802	0.000
I30.1 Infective pericarditis	0.191	0.809	0.000
I31 Other diseases of pericardium	0.182	0.818	0.000
I42 Cardiomyopathy	0.170	0.830	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.167	0.833	0.000
E10 Insulin-dependent diabetes mellitus	0.165	0.835	0.000
I00-I02 Acute rheumatic fever	0.165	0.835	0.000
I30.8 Other forms of acute pericarditis	0.162	0.838	0.000
I42.0 Dilated cardiomyopathy	0.162	0.838	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.160	0.840	0.000
I44.4 Left anterior fascicular block	0.158	0.842	0.000
I31.9 Disease of pericardium, unspecified	0.157	0.843	0.000
I31.0 Chronic adhesive pericarditis	0.157	0.843	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.154	0.845	0.000
I52 Other heart disorders in diseases classified elsewhere	0.153	0.847	0.000
I48 Atrial fibrillation and flutter	0.153	0.847	0.000
I41 Myocarditis in diseases classified elsewhere	0.153	0.847	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.153	0.847	0.000
I32 Pericarditis in diseases classified elsewhere	0.153	0.847	0.000
E10.0 With coma	0.149	0.851	0.000
I88 Nonspecific lymphadenitis	0.147	0.853	0.000
I34.1 Mitral (valve) prolapse	0.147	0.853	0.000
E10.8 With unspecified complications	0.145	0.855	0.000
E10.4 With neurological complications	0.144	0.856	0.000
I40 Acute myocarditis	0.141	0.859	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.136	0.864	0.000
I00 Rheumatic fever without mention of heart involvement	0.132	0.868	0.000
I44.7 Left bundle-branch block, unspecified	0.131	0.869	0.000
I42.2 Other hypertrophic cardiomyopathy	0.131	0.869	0.000
I31.8 Other specified diseases of pericardium	0.131	0.869	0.000
I31.2 Haemopericardium, not elsewhere classified	0.131	0.869	0.000
I45 Other conduction disorders	0.126	0.874	0.000
I37 Pulmonary valve disorders	0.125	0.875	0.000
E10.2 With renal complications	0.125	0.875	0.000
E10.1 With ketoacidosis	0.125	0.875	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.122	0.877	0.000
I42.5 Other restrictive cardiomyopathy	0.122	0.878	0.000
I42.4 Endocardial fibroelastosis	0.122	0.878	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.122	0.878	0.000
I45.3 Trifascicular block	0.122	0.878	0.000
E10.7 With multiple complications	0.119	0.881	0.000
I33 Acute and subacute endocarditis	0.119	0.881	0.000
I02 Rheumatic chorea	0.118	0.882	0.000
I01 Rheumatic fever with heart involvement	0.118	0.882	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.117	0.883	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.117	0.883	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.116	0.884	0.000
I42.6 Alcoholic cardiomyopathy	0.116	0.884	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.115	0.885	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.115	0.885	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.115	0.885	0.000
I31.1 Chronic constrictive pericarditis	0.114	0.886	0.000
I31.3 Pericardial effusion (noninflammatory)	0.113	0.887	0.000
I10-I15 Hypertensive diseases	0.112	0.888	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.110	0.890	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.110	0.890	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.110	0.890	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.110	0.890	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.110	0.890	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.110	0.890	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.110	0.890	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.110	0.890	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.110	0.890	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.110	0.890	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.110	0.890	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.110	0.890	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.110	0.890	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.110	0.890	0.000
I48.4 Atypical atrial flutter	0.110	0.890	0.000
I48.3 Typical atrial flutter	0.110	0.890	0.000
I48.2 Chronic atrial fibrillation	0.110	0.890	0.000
I48.1 Persistent atrial fibrillation	0.110	0.890	0.000
I48.0 Paroxysmal atrial fibrillation	0.110	0.890	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.110	0.890	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.110	0.890	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.110	0.890	0.000
I45.9 Conduction disorder, unspecified	0.109	0.891	0.000
I36 Nonrheumatic tricuspid valve disorders	0.107	0.893	0.000
I40.9 Acute myocarditis, unspecified	0.106	0.894	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.106	0.894	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.106	0.894	0.000
I81 Portal vein thrombosis	0.104	0.896	0.000
I88.8 Other nonspecific lymphadenitis	0.102	0.897	0.000
I05-I09 Chronic rheumatic heart diseases	0.103	0.897	0.000
E10.6 With other specified complications	0.101	0.898	0.000
I40.8 Other acute myocarditis	0.101	0.899	0.000
I40.1 Isolated myocarditis	0.101	0.899	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.100	0.900	0.000
I45.5 Other specified heart block	0.100	0.900	0.000
E10.9 Without complications	0.095	0.905	0.000
I85 Oesophageal varices	0.094	0.906	0.000
I86 Varicose veins of other sites	0.093	0.907	0.000
I37.9 Pulmonary valve disorder, unspecified	0.090	0.910	0.000
I37.8 Other pulmonary valve disorders	0.090	0.910	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.090	0.910	0.000
I45.0 Right fascicular block	0.089	0.910	0.000
I46 Cardiac arrest	0.089	0.911	0.000
I45.4 Nonspecific intraventricular block	0.089	0.911	0.000
I15 Secondary hypertension	0.088	0.912	0.000
I51 Complications and ill-defined descriptions of heart disease	0.088	0.912	0.000
I42.9 Cardiomyopathy, unspecified	0.088	0.912	0.000
I37.0 Pulmonary valve stenosis	0.087	0.913	0.000
I06 Rheumatic aortic valve diseases	0.086	0.914	0.000
E10.5 With peripheral circulatory complications	0.086	0.914	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.085	0.915	0.000
I01.8 Other acute rheumatic heart disease	0.085	0.915	0.000
I01.2 Acute rheumatic myocarditis	0.085	0.915	0.000
I01.1 Acute rheumatic endocarditis	0.085	0.915	0.000
I01.0 Acute rheumatic pericarditis	0.085	0.915	0.000
I02.9 Rheumatic chorea without heart involvement	0.085	0.915	0.000
I02.0 Rheumatic chorea with heart involvement	0.085	0.915	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.085	0.915	0.000
I13 Hypertensive heart and renal disease	0.085	0.915	0.000
I12 Hypertensive renal disease	0.082	0.918	0.000
I40.0 Infective myocarditis	0.081	0.918	0.000
I11 Hypertensive heart disease	0.081	0.919	0.000
I45.8 Other specified conduction disorders	0.081	0.919	0.000
I09 Other rheumatic heart diseases	0.080	0.920	0.000
I42.8 Other cardiomyopathies	0.079	0.921	0.000
I33.9 Acute endocarditis, unspecified	0.079	0.921	0.000
I82 Other venous embolism and thrombosis	0.079	0.921	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.077	0.923	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.077	0.923	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.077	0.923	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.077	0.923	0.000
I86.1 Scrotal varices	0.076	0.924	0.000
I06.0 Rheumatic aortic stenosis	0.075	0.925	0.000
I51.0 Cardiac septal defect, acquired	0.072	0.928	0.000
I07 Rheumatic tricuspid valve diseases	0.072	0.928	0.000
I51.4 Myocarditis, unspecified	0.071	0.929	0.000
I51.9 Heart disease, unspecified	0.068	0.932	0.000
I15.9 Seconday hypertension, unspecified	0.068	0.932	0.000
I15.2 Hypertension secondary to endocrine disorders	0.067	0.933	0.000
I86.0 Sublingual varices	0.067	0.933	0.000
I37.1 Pulmonary valve insufficiency	0.067	0.933	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.066	0.934	0.000
I15.0 Renovascular hypertension	0.065	0.935	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.065	0.935	0.000
I12.9 Hypertensive renal disease without renal failure	0.064	0.936	0.000
I46.1 Sudden cardiac death, so described	0.064	0.936	0.000
I09.9 Rheumatic heart disease, unspecified	0.064	0.936	0.000
I50 Heart failure	0.064	0.936	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.064	0.936	0.000
I86.3 Vulval varices	0.064	0.936	0.000
I15.8 Other secondary hypertension	0.063	0.936	0.000
I51.5 Myocardial degeneration	0.063	0.937	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.063	0.937	0.000
I06.1 Rheumatic aortic insufficiency	0.063	0.937	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.062	0.938	0.000
I06.8 Other rheumatic aortic valve diseases	0.062	0.938	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.062	0.938	0.000
I15.1 Hypertension secondary to other renal disorders	0.062	0.938	0.000
I82.0 Budd-Chiari syndrome	0.062	0.938	0.000
I33.0 Acute and subacute infective endocarditis	0.061	0.939	0.000
I86.2 Pelvic varices	0.061	0.939	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.061	0.939	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.061	0.939	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.061	0.939	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.059	0.941	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.058	0.942	0.000
I09.8 Other specified rheumatic heart diseases	0.058	0.942	0.000
I09.2 Chronic rheumatic pericarditis	0.058	0.942	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.058	0.942	0.000
I09.0 Rheumatic myocarditis	0.058	0.942	0.000
I85.0 Oesophageal varices with bleeding	0.057	0.943	0.000
I82.1 Thrombophlebitis migrans	0.057	0.943	0.000
I83 Varicose veins of lower extremities	0.055	0.945	0.000
I87 Other disorders of veins	0.054	0.946	0.000
I50.9 Heart failure, unspecified	0.054	0.946	0.000
I38 Endocarditis, valve unspecified	0.053	0.946	0.000
I12.0 Hypertensive renal disease with renal failure	0.053	0.947	0.000
I82.3 Embolism and thrombosis of renal vein	0.052	0.947	0.000
I07.9 Tricuspid valve disease, unspecified	0.052	0.948	0.000
I07.8 Other tricuspid valve diseases	0.052	0.948	0.000
I07.2 Tricuspid stenosis with insufficiency	0.052	0.948	0.000
I07.0 Tricuspid stenosis	0.052	0.948	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.052	0.948	0.000
I95 Hypotension	0.051	0.949	0.000
I51.6 Cardiovascular disease, unspecified	0.051	0.949	0.000
I44.1 Atrioventricular block, second degree	0.051	0.949	0.000
I07.1 Tricuspid insufficiency	0.050	0.950	0.000
I82.2 Embolism and thrombosis of vena cava	0.050	0.950	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.049	0.951	0.000
I86.4 Gastric varices	0.048	0.951	0.000
F52.2 Failure of genital response	0.048	0.952	0.000
I05 Rheumatic mitral valve diseases	0.048	0.952	0.000
I97.1 Other functional disturbances following cardiac surgery	0.048	0.952	0.000
I51.8 Other ill-defined heart diseases	0.048	0.952	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.047	0.953	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.047	0.953	0.000
I86.8 Varicose veins of other specified sites	0.046	0.953	0.000
I46.0 Cardiac arrest with successful resuscitation	0.046	0.954	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.046	0.954	0.000
I97.0 Postcardiotomy syndrome	0.046	0.954	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.043	0.957	0.000
I95.0 Idiopathic hypotension	0.042	0.958	0.000
I05.0 Mitral stenosis	0.041	0.959	0.000
I95.8 Other hypotension	0.041	0.959	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.959	0.041
I85.9 Oesophageal varices without bleeding	0.040	0.960	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.040	0.960	0.000
I87.0 Postphlebitic syndrome	0.039	0.961	0.000
I99 Other and unspecified disorders of circulatory system	0.039	0.961	0.000
I87.9 Disorder of vein, unspecified	0.038	0.961	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.038	0.962	0.000
I45.2 Bifascicular block	0.037	0.962	0.001
I46.9 Cardiac arrest, unspecified	0.037	0.963	0.000
I47 Paroxysmal tachycardia	0.037	0.963	0.000
I05.8 Other mitral valve diseases	0.035	0.965	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.034	0.966	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.034	0.966	0.000
I98.0 Cardiovascular syphilis	0.034	0.966	0.000
R82.9 Other and unspecified abnormal finding in urine	0.033	0.967	0.000
I95.1 Orthostatic hypotension	0.033	0.967	0.000
I87.8 Other specified disorders of veins	0.032	0.968	0.000
I45.6 Preexcitation syndrome	0.032	0.968	0.000
I82.8 Embolism and thrombosis of other specified veins	0.031	0.969	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.030	0.969	0.001
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.030	0.970	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.029	0.971	0.000
I95.2 Hypotension due to drugs	0.029	0.971	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.028	0.972	0.000
I47.0 Reentry ventricular arrhythmia	0.028	0.972	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.028	0.972	0.000
I95.9 Hypotension, unspecified	0.027	0.973	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.026	0.973	0.000
I05.2 Mitral stenosis with insufficiency	0.025	0.975	0.000
I05.9 Mitral valve disease, unspecified	0.025	0.975	0.000
E10-E14 Diabetes mellitus	0.024	0.976	0.000
I05.1 Rheumatic mitral insufficiency	0.024	0.976	0.000
E13 Other specified diabetes mellitus	0.022	0.978	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.022	0.978	0.000
I87.1 Compression of vein	0.022	0.978	0.000
F52.0 Lack or loss of sexual desire	0.022	0.978	0.000
R82 Other abnormal findings in urine	0.022	0.978	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.979	0.021
H73 Other disorders of tympanic membrane	0.000	0.979	0.021
H02.6 Xanthelasma of eyelid	0.000	0.979	0.021
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.020	0.979	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.021	0.979	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.021	0.979	0.000
F52.7 Excessive sexual drive	0.021	0.979	0.000
F52.6 Nonorganic dyspareunia	0.021	0.979	0.000
F52.5 Nonorganic vaginismus	0.021	0.979	0.000
F52.4 Premature ejaculation	0.021	0.979	0.000
F52.3 Orgasmic dysfunction	0.021	0.979	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.021	0.979	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.979	0.021
D47.4 Osteomyelofibrosis	0.000	0.980	0.020
I49 Other cardiac arrhythmias	0.020	0.980	0.000
E13.9 Without complications	0.020	0.980	0.000
I35 Nonrheumatic aortic valve disorders	0.020	0.980	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.019	0.981	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.019	0.981	0.000
I51.7 Cardiomegaly	0.018	0.982	0.000
R82.4 Acetonuria	0.018	0.982	0.000
E12 Malnutrition-related diabetes mellitus	0.018	0.982	0.000
E13.3 With ophthalmic complications	0.017	0.982	0.000
I89.1 Lymphangitis	0.017	0.983	0.000
I45.1 Other and unspecified right bundle-branch block	0.017	0.983	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.983	0.017
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.984	0.016
I49.5 Sick sinus syndrome	0.016	0.984	0.000
H73.1 Chronic myringitis	0.000	0.984	0.016
E13.8 With unspecified complications	0.016	0.984	0.000
E13.7 With multiple complications	0.016	0.984	0.000
E13.6 With other specified complications	0.016	0.984	0.000
E13.5 With peripheral circulatory complications	0.016	0.984	0.000
E13.4 With neurological complications	0.016	0.984	0.000
E13.2 With renal complications	0.016	0.984	0.000
E13.1 With ketoacidosis	0.016	0.984	0.000
E13.0 With coma	0.016	0.984	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.984	0.016
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.016	0.984	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.016	0.984	0.000
R82.3 Haemoglobinuria	0.016	0.984	0.000
R82.2 Biliuria	0.016	0.984	0.000
R82.0 Chyluria	0.016	0.984	0.000
R82.1 Myoglobinuria	0.016	0.984	0.000
H73.0 Acute myringitis	0.000	0.984	0.015
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.985	0.015
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.985	0.015
I49.2 Junctional premature depolarisation	0.015	0.985	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.985	0.015
D47.2 Monoclonal gammopathy	0.000	0.985	0.015
I49.1 Atrial premature depolarisation	0.014	0.986	0.000
I35.8 Other aortic valve disorders	0.014	0.986	0.000
I08 Multiple valve diseases	0.013	0.987	0.000
E12.9 Without complications	0.013	0.987	0.000
E12.8 With unspecified complications	0.013	0.987	0.000
E12.7 With multiple complications	0.013	0.987	0.000
E12.6 With other specified complications	0.013	0.987	0.000
E12.5 With peripheral circulatory complications	0.013	0.987	0.000
E12.4 With neurological complications	0.013	0.987	0.000
E12.3 With ophthalmic complications	0.013	0.987	0.000
E12.2 With renal complications	0.013	0.987	0.000
E12.1 With ketoacidosis	0.013	0.987	0.000
E12.0 With coma	0.013	0.987	0.000
D41.0 Kidney	0.000	0.987	0.013
I49.0 Ventricular fibrillation and flutter	0.013	0.987	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.012	0.988	0.000
I83.1 Varicose veins of lower extremities with inflammation	0.011	0.989	0.000
I49.8 Other specified cardiac arrhythmias	0.011	0.989	0.000
Z92 Personal history of medical treatment	0.011	0.989	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.011	0.989	0.000
I35.9 Aortic valve disorder, unspecified	0.011	0.989	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.989	0.011
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.011	0.989	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.010	0.990	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.990	0.010
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.990	0.010
I74 Arterial embolism and thrombosis	0.010	0.990	0.000
D43.2 Brain, unspecified	0.000	0.990	0.010
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.010	0.990	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.010	0.990	0.000
I47.2 Ventricular tachycardia	0.010	0.990	0.000
Z92.5 Personal history of rehabilitation measures	0.009	0.991	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.991	0.009
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.991	0.009
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.009	0.991	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.009	0.991	0.000
F51 Nonorganic sleep disorders	0.009	0.991	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.009	0.991	0.000
I08.9 Multiple valve disease, unspecified	0.009	0.991	0.000
D48.7 Other specified sites	0.000	0.991	0.009
D44.3 Pituitary gland	0.000	0.991	0.009
I74.9 Embolism and thrombosis of unspecified artery	0.009	0.991	0.000
I50.0 Congestive heart failure	0.009	0.991	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.009	0.991	0.000
D48.1 Connective and other soft tissue	0.000	0.991	0.008
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.008	0.991	0.000
Z92.9 Personal history of medical treatment, unspecified	0.008	0.992	0.000
D43.0 Brain, supratentorial	0.000	0.992	0.008
I35.2 Aortic (valve) stenosis with insufficiency	0.008	0.992	0.000
D48.0 Bone and articular cartilage	0.000	0.992	0.008
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.992	0.008
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.008	0.992	0.000
F55 Abuse of non-dependence-producing substances	0.008	0.992	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.008	0.992	0.000
I49.4 Other and unspecified premature depolarisation	0.008	0.992	0.000
Z92.8 Personal history of other medical treatment	0.008	0.992	0.000
D46 Myelodysplastic syndromes	0.000	0.992	0.008
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.992	0.008
I78 Diseases of capillaries	0.008	0.992	0.000
D43.1 Brain, infratentorial	0.000	0.992	0.008
I35.1 Aortic (valve) insufficiency	0.008	0.992	0.000
I70 Atherosclerosis	0.008	0.992	0.000
D43.9 Central nervous system, unspecified	0.000	0.992	0.008
D43.7 Other parts of central nervous system	0.000	0.992	0.008
D43.3 Cranial nerves	0.000	0.992	0.008
D41.9 Urinary organ, unspecified	0.000	0.992	0.007
D41.7 Other urinary organs	0.000	0.992	0.007
D41.3 Urethra	0.000	0.992	0.007
I08.2 Disorders of both aortic and tricuspid valves	0.007	0.992	0.000
I74.8 Embolism and thrombosis of other arteries	0.008	0.992	0.000
D44.4 Craniopharyngeal duct	0.000	0.993	0.007
I89.0 Lymphoedema, not elsewhere classified	0.007	0.993	0.000
D41.2 Ureter	0.000	0.993	0.007
I74.5 Embolism and thrombosis of iliac artery	0.007	0.993	0.000
D48.4 Peritoneum	0.000	0.993	0.007
I08.1 Disorders of both mitral and tricuspid valves	0.007	0.993	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.993	0.007
D44.8 Pluriglandular involvement	0.000	0.993	0.007
I78.0 Hereditary haemorrhagic telangiectasia	0.007	0.993	0.000
F53.0 Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.007	0.993	0.000
D43.4 Spinal cord	0.000	0.993	0.007
F51.4 Sleep terrors [night terrors]	0.007	0.993	0.000
D41.1 Renal pelvis	0.000	0.993	0.007
F51.0 Nonorganic insomnia	0.007	0.993	0.000
D48.3 Retroperitoneum	0.000	0.993	0.007
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.993	0.007
D46.4 Refractory anaemia, unspecified	0.000	0.993	0.007
I63.8 Other cerebral infarction	0.007	0.993	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.007	0.993	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.007	0.993	0.000
D44.9 Endocrine gland, unspecified	0.000	0.993	0.007
D44.5 Pineal gland	0.000	0.993	0.007
D44.2 Parathyroid gland	0.000	0.993	0.007
D44.7 Aortic body and other paraganglia	0.000	0.993	0.007
I63 Cerebral infarction	0.007	0.993	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.007	0.993	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.993	0.007
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.993	0.007
F53.9 Puerperal mental disorder, unspecified	0.006	0.993	0.000
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.006	0.993	0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.006	0.993	0.000
D46.1 Refractory anaemia with sideroblasts	0.000	0.993	0.007
D44.0 Thyroid gland	0.000	0.993	0.006
F51.9 Nonorganic sleep disorder, unspecified	0.006	0.993	0.000
F51.8 Other nonorganic sleep disorders	0.006	0.993	0.000
F51.2 Nonorganic disorder of the sleep-wake schedule	0.006	0.993	0.000
F51.1 Nonorganic hypersomnia	0.006	0.993	0.000
I79.1 Aortitis in diseases classified elsewhere	0.006	0.993	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.006	0.993	0.000
F51.3 Sleepwalking [somnambulism]	0.006	0.993	0.000
D46.2 Refractory anaemia with excess of blasts	0.000	0.993	0.006
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.994	0.006
D44.6 Carotid body	0.000	0.994	0.006
F50 Eating disorders	0.006	0.994	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.006	0.994	0.000
I78.8 Other diseases of capillaries	0.006	0.994	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.000	0.994	0.006
D46.5 Refractory anaemia with multi-lineage dysplasia	0.000	0.994	0.006
D46.3 Refractory anaemia with excess of blasts with transformation	0.000	0.994	0.006
D46.0 Refractory anaemia without sideroblasts, so stated	0.000	0.994	0.006
I70.8 Atherosclerosis of other arteries	0.006	0.994	0.000
I70.1 Atherosclerosis of renal artery	0.006	0.994	0.000
D42.9 Meninges, unspecified	0.000	0.994	0.006
D42.1 Spinal meninges	0.000	0.994	0.006
D42.0 Cerebral meninges	0.000	0.994	0.006
I78.9 Disease of capillaries, unspecified	0.006	0.994	0.000
F51.5 Nightmares	0.006	0.994	0.000
R81 Glycosuria	0.006	0.994	0.000
I70.9 Generalised and unspecified atherosclerosis	0.006	0.994	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.006	0.994	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.006	0.994	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.006	0.994	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.994	0.006
D38.1 Trachea, bronchus and lung	0.000	0.994	0.006
D40.9 Male genital organ, unspecified	0.000	0.994	0.005
D40.7 Other male genital organs	0.000	0.994	0.005
I60-I69 Cerebrovascular diseases	0.005	0.994	0.000
D44.1 Adrenal gland	0.000	0.995	0.005
I08.8 Other multiple valve diseases	0.005	0.995	0.000
D46.7 Other myelodysplastic syndromes	0.000	0.995	0.005
D38.6 Respiratory organ, unspecified	0.000	0.995	0.005
D38.4 Thymus	0.000	0.995	0.005
D38.2 Pleura	0.000	0.995	0.005
D40.0 Prostate	0.000	0.995	0.005
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.005	0.995	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.005	0.995	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.005	0.995	0.000
D40.1 Testis	0.000	0.995	0.005
E83.4 Disorders of magnesium metabolism	0.000	0.995	0.005
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.005	0.995	0.000
I70.0 Atherosclerosis of aorta	0.005	0.995	0.000
D38.5 Other respiratory organs	0.000	0.995	0.005
F50.0 Anorexia nervosa	0.005	0.995	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.005	0.995	0.000
S81.9 Open wound of lower leg, part unspecified	0.005	0.995	0.000
F50.8 Other eating disorders	0.005	0.995	0.000
F50.5 Vomiting associated with other psychological disturbances	0.005	0.995	0.000
F50.4 Overeating associated with other psychological disturbances	0.005	0.995	0.000
F50.3 Atypical bulimia nervosa	0.005	0.995	0.000
F50.1 Atypical anorexia nervosa	0.005	0.995	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.005	0.995	0.000
I72 Other aneurysm	0.005	0.995	0.000
E83 Disorders of mineral metabolism	0.000	0.995	0.005
I70.2 Atherosclerosis of arteries of the extremities	0.005	0.995	0.000
I49.9 Cardiac arrhythmia, unspecified	0.005	0.995	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.004	0.995	0.000
D38.0 Larynx	0.000	0.995	0.004
D38.3 Mediastinum	0.000	0.995	0.004
I70.11 Atherosclerosis of renal artery (with gangrene)	0.004	0.995	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.004	0.995	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.004	0.996	0.000
I49.3 Ventricular premature depolarisation	0.004	0.996	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.996	0.004
D39.9 Female genital organ, unspecified	0.000	0.996	0.004
D39.2 Placenta	0.000	0.996	0.004
S81.7 Multiple open wounds of lower leg	0.004	0.996	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.004	0.996	0.000
F50.2 Bulimia nervosa	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations