TreeWAS – Variant ID: rs4319543

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M10.99 Gout, unspecified (Site unspecified)	0.000	0.846	0.154
M10.9 Gout, unspecified	0.000	0.938	0.062
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.945	0.055
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.951	0.049
M10.94 Gout, unspecified (Hand)	0.000	0.954	0.046
M10.98 Gout, unspecified (Other)	0.000	0.955	0.045
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.955	0.045
M10.91 Gout, unspecified (Shoulder region)	0.000	0.955	0.045
M10.93 Gout, unspecified (Forearm)	0.000	0.958	0.042
M10.92 Gout, unspecified (Upper arm)	0.000	0.960	0.040
M10 Gout	0.000	0.960	0.040
M10.90 Gout, unspecified (Multiple sites)	0.000	0.961	0.039
M10.0 Idiopathic gout	0.000	0.964	0.036
M10.06 Idiopathic gout (Lower leg)	0.000	0.971	0.029
M10.4 Other secondary gout	0.000	0.971	0.029
M10.2 Drug-induced gout	0.000	0.971	0.029
M10.1 Lead-induced gout	0.000	0.971	0.029
M10.04 Idiopathic gout (Hand)	0.000	0.972	0.028
M10.07 Idiopathic gout (Ankle and foot)	0.000	0.972	0.028
M10.09 Idiopathic gout (Site unspecified)	0.000	0.972	0.028
M10.3 Gout due to impairment of renal function	0.000	0.972	0.027
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.973	0.027
M10.02 Idiopathic gout (Upper arm)	0.000	0.973	0.026
M10.00 Idiopathic gout (Multiple sites)	0.000	0.974	0.026
M10.08 Idiopathic gout (Other)	0.000	0.974	0.026
M10.05 Idiopathic gout (Pelvic region and thigh)	0.000	0.974	0.026
M10.03 Idiopathic gout (Forearm)	0.000	0.974	0.026
M10.01 Idiopathic gout (Shoulder region)	0.000	0.974	0.026
M10.96 Gout, unspecified (Lower leg)	0.000	0.975	0.025
M10.19 Lead-induced gout (Site unspecified)	0.000	0.979	0.021
M10.18 Lead-induced gout (Other)	0.000	0.979	0.021
M10.17 Lead-induced gout (Ankle and foot)	0.000	0.979	0.021
M10.16 Lead-induced gout (Lower leg)	0.000	0.979	0.021
M10.15 Lead-induced gout (Pelvic region and thigh)	0.000	0.979	0.021
M10.14 Lead-induced gout (Hand)	0.000	0.979	0.021
M10.13 Lead-induced gout (Forearm)	0.000	0.979	0.021
M10.12 Lead-induced gout (Upper arm)	0.000	0.979	0.021
M10.11 Lead-induced gout (Shoulder region)	0.000	0.979	0.021
M10.10 Lead-induced gout (Multiple sites)	0.000	0.979	0.021
M10.29 Drug-induced gout (Site unspecified)	0.000	0.979	0.021
M10.28 Drug-induced gout (Other)	0.000	0.979	0.021
M10.27 Drug-induced gout (Ankle and foot)	0.000	0.979	0.021
M10.26 Drug-induced gout (Lower leg)	0.000	0.979	0.021
M10.25 Drug-induced gout (Pelvic region and thigh)	0.000	0.979	0.021
M10.24 Drug-induced gout (Hand)	0.000	0.979	0.021
M10.23 Drug-induced gout (Forearm)	0.000	0.979	0.021
M10.22 Drug-induced gout (Upper arm)	0.000	0.979	0.021
M10.21 Drug-induced gout (Shoulder region)	0.000	0.979	0.021
M10.20 Drug-induced gout (Multiple sites)	0.000	0.979	0.021
M10.49 Other secondary gout (Site unspecified)	0.000	0.979	0.021
M10.48 Other secondary gout (Other)	0.000	0.979	0.021
M10.47 Other secondary gout (Ankle and foot)	0.000	0.979	0.021
M10.46 Other secondary gout (Lower leg)	0.000	0.979	0.021
M10.45 Other secondary gout (Pelvic region and thigh)	0.000	0.979	0.021
M10.44 Other secondary gout (Hand)	0.000	0.979	0.021
M10.43 Other secondary gout (Forearm)	0.000	0.979	0.021
M10.42 Other secondary gout (Upper arm)	0.000	0.979	0.021
M10.41 Other secondary gout (Shoulder region)	0.000	0.979	0.021
M10.40 Other secondary gout (Multiple sites)	0.000	0.979	0.021
M10.38 Gout due to impairment of renal function (Other)	0.000	0.980	0.020
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.000	0.980	0.020
M10.36 Gout due to impairment of renal function (Lower leg)	0.000	0.980	0.020
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.000	0.980	0.020
M10.34 Gout due to impairment of renal function (Hand)	0.000	0.980	0.020
M10.33 Gout due to impairment of renal function (Forearm)	0.000	0.980	0.020
M10.32 Gout due to impairment of renal function (Upper arm)	0.000	0.980	0.020
M10.31 Gout due to impairment of renal function (Shoulder region)	0.000	0.980	0.020
M10.30 Gout due to impairment of renal function (Multiple sites)	0.000	0.980	0.020
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.980	0.019
M10.39 Gout due to impairment of renal function (Site unspecified)	0.000	0.981	0.019
S82.00 Fracture of patella (closed)	0.000	0.988	0.012
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.989	0.011
H71 Cholesteatoma of middle ear	0.000	0.989	0.011
I84.6 Residual haemorrhoidal skin tags	0.010	0.990	0.000
H92.0 Otalgia	0.000	0.991	0.009
G95.9 Disease of spinal cord, unspecified	0.008	0.992	0.000
I49.8 Other specified cardiac arrhythmias	0.008	0.992	0.000
H92.1 Otorrhoea	0.000	0.993	0.007
H92 Otalgia and effusion of ear	0.000	0.993	0.007
H65.2 Chronic serous otitis media	0.000	0.993	0.007
B97 Viral agents as the cause of diseases classified to other chapters	0.000	0.993	0.007
H65-H75 Diseases of middle ear and mastoid	0.000	0.993	0.007
H73 Other disorders of tympanic membrane	0.000	0.993	0.007
H65 Nonsuppurative otitis media	0.000	0.993	0.007
B95-B98 Bacterial, viral and other infectious agents	0.000	0.993	0.007
H73.8 Other specified disorders of tympanic membrane	0.000	0.993	0.007
H66 Suppurative and unspecified otitis media	0.000	0.994	0.006
H65.3 Chronic mucoid otitis media	0.000	0.994	0.006
I50.1 Left ventricular failure	0.006	0.994	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.994	0.006
H66.9 Otitis media, unspecified	0.000	0.994	0.006
H69 Other disorders of Eustachian tube	0.000	0.994	0.006
H68 Eustachian salpingitis and obstruction	0.000	0.994	0.005
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.000	0.995	0.005
B97.5 Reovirus as the cause of diseases classified to other chapters	0.000	0.995	0.005
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.000	0.995	0.005
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.000	0.995	0.005
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.000	0.995	0.005
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.995	0.005
H67 Otitis media in diseases classified elsewhere	0.000	0.995	0.005
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.000	0.995	0.005
H65.0 Acute serous otitis media	0.000	0.995	0.005
H66.3 Other chronic suppurative otitis media	0.000	0.995	0.005
H73.0 Acute myringitis	0.000	0.995	0.005
H69.8 Other specified disorders of Eustachian tube	0.000	0.995	0.005
S82.0 Fracture of patella	0.000	0.995	0.005
R10.0 Acute abdomen	0.000	0.995	0.005
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.000	0.995	0.005
H65.4 Other chronic nonsuppurative otitis media	0.000	0.995	0.005
F40.2 Specific (isolated) phobias	0.005	0.995	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.995	0.005
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.995	0.005
H70 Mastoiditis and related conditions	0.000	0.995	0.005
H73.1 Chronic myringitis	0.000	0.995	0.004
H66.0 Acute suppurative otitis media	0.000	0.996	0.004
H68.1 Obstruction of Eustachian tube	0.000	0.996	0.004
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.996	0.004
H65.1 Other acute nonsuppurative otitis media	0.000	0.996	0.004
H69.0 Patulous Eustachian tube	0.000	0.996	0.004
H68.0 Eustachian salpingitis	0.000	0.996	0.004
H92.2 Otorrhagia	0.000	0.996	0.004
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.996	0.004
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.996	0.004
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.996	0.004
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.996	0.004
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
H66.4 Suppurative otitis media, unspecified	0.000	0.996	0.004
H70.8 Other mastoiditis and related conditions	0.000	0.996	0.004
G95 Other diseases of spinal cord	0.004	0.996	0.000
H90-H95 Other disorders of ear	0.000	0.996	0.004
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.996	0.004
H70.2 Petrositis	0.000	0.996	0.003
H70.0 Acute mastoiditis	0.000	0.996	0.003
H70.1 Chronic mastoiditis	0.000	0.996	0.003
S82.01 Fracture of patella (open)	0.000	0.997	0.003
G95.0 Syringomyelia and syringobulbia	0.003	0.997	0.000
H69.9 Eustachian tube disorder, unspecified	0.000	0.997	0.003
Chapter VIII Diseases of the ear and mastoid process	0.000	0.997	0.003
G90.0 Idiopathic peripheral autonomic neuropathy	0.003	0.997	0.000
K74.0 Hepatic fibrosis	0.000	0.997	0.003
B99 Other and unspecified infectious diseases	0.000	0.997	0.003
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.997	0.003
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.997	0.003
Q44.6 Cystic disease of liver	0.000	0.997	0.003
H94 Other disorders of ear in diseases classified elsewhere	0.000	0.997	0.003
G71.0 Muscular dystrophy	0.000	0.997	0.003
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.997	0.003
G96.0 Cerebrospinal fluid leak	0.003	0.997	0.000
G70.0 Myasthenia gravis	0.000	0.997	0.003
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.003	0.997	0.000
G72.9 Myopathy, unspecified	0.000	0.997	0.003
K26.3 Acute without haemorrhage or perforation	0.000	0.997	0.003
G90 Disorders of autonomic nervous system	0.003	0.997	0.000
G95.2 Cord compression, unspecified	0.003	0.997	0.000
G72 Other myopathies	0.000	0.997	0.003
Z52.8 Donor of other organs and tissues	0.003	0.997	0.000
G95.1 Vascular myelopathies	0.003	0.997	0.000
T87.6 Other and unspecified complications of amputation stump	0.003	0.997	0.000
D48.6 Breast	0.000	0.997	0.003
Y40.9 Systemic antibiotic, unspecified	0.000	0.997	0.003
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.997	0.002
N36.0 Urethral fistula	0.000	0.997	0.002
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
H70.9 Mastoiditis, unspecified	0.000	0.998	0.002
G71 Primary disorders of muscles	0.000	0.998	0.002
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.000	0.998	0.002
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.998	0.002
G96 Other disorders of central nervous system	0.002	0.998	0.000
H90 Conductive and sensorineural hearing loss	0.000	0.998	0.002
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.002	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.998	0.002
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.000	0.998	0.002
H93 Other disorders of ear, not elsewhere classified	0.000	0.998	0.002
G72.8 Other specified myopathies	0.000	0.998	0.002
G72.1 Alcoholic myopathy	0.000	0.998	0.002
J43.2 Centrilobular emphysema	0.002	0.998	0.000
G70 Myasthenia gravis and other myoneural disorders	0.000	0.998	0.002
G90.3 Multisystem degeneration	0.002	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.002	0.998	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.998	0.002
G90.2 Horner's syndrome	0.002	0.998	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.002	0.998	0.000
G90.4 Autonomic dysreflexia	0.002	0.998	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.002	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
G70-G73 Diseases of myoneural junction and muscle	0.000	0.998	0.002
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.998	0.000
G72.3 Periodic paralysis	0.000	0.998	0.002
G72.2 Myopathy due to other toxic agents	0.000	0.998	0.002
G72.0 Drug-induced myopathy	0.000	0.998	0.002
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.000	0.998	0.002
G90-G99 Other disorders of the nervous system	0.002	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.002	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.998	0.002
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.998	0.000
T87.4 Infection of amputation stump	0.002	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.998	0.002
G71.1 Myotonic disorders	0.000	0.998	0.002
G98 Other disorders of nervous system, not elsewhere classified	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.998	0.002
Z74.0 Reduced mobility	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.998	0.002
G71.9 Primary disorder of muscle, unspecified	0.000	0.998	0.002
G71.8 Other primary disorders of muscles	0.000	0.998	0.002
G71.2 Congenital myopathies	0.000	0.998	0.002
G90.8 Other disorders of autonomic nervous system	0.002	0.998	0.000
G96.8 Other specified disorders of central nervous system	0.002	0.998	0.000
G96.9 Disorder of central nervous system, unspecified	0.002	0.998	0.000
H93.2 Other abnormal auditory perceptions	0.000	0.998	0.002
S42.10 Fracture of scapula (closed)	0.000	0.998	0.002
Q44.5 Other congenital malformations of bile ducts	0.000	0.998	0.002
M67.2 Synovial hypertrophy, not elsewhere classified	0.002	0.998	0.000
G92 Toxic encephalopathy	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.000	0.998	0.002
H93.0 Degenerative and vascular disorders of ear	0.000	0.998	0.002
S67 Crushing injury of wrist and hand	0.000	0.998	0.002
M25.87 Other specified joint disorders (Ankle and foot)	0.002	0.998	0.000
G70.8 Other specified myoneural disorders	0.000	0.998	0.002
G70.2 Congenital and developmental myasthenia	0.000	0.998	0.002
G70.1 Toxic myoneural disorders	0.000	0.998	0.002
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.998	0.002
H93.3 Disorders of acoustic nerve	0.000	0.998	0.002
R09.3 Abnormal sputum	0.000	0.998	0.002
G95.8 Other specified diseases of spinal cord	0.002	0.998	0.000
Q38.7 Pharyngeal pouch	0.000	0.998	0.002
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.002	0.998	0.000
G43.1 Migraine with aura [classical migraine]	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.998	0.002
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.002
Q44.3 Congenital stenosis and stricture of bile ducts	0.000	0.998	0.002
Q44.2 Atresia of bile ducts	0.000	0.998	0.002
Q44.1 Other congenital malformations of gallbladder	0.000	0.998	0.002
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.000	0.998	0.002
T87 Complications peculiar to reattachment and amputation	0.002	0.998	0.000
M25.86 Other specified joint disorders (Lower leg)	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.998	0.002
D47.2 Monoclonal gammopathy	0.000	0.998	0.002
Q44.4 Choledochal cyst	0.000	0.998	0.002
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.998	0.002
Q44.7 Other congenital malformations of liver	0.000	0.998	0.002
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
H93.8 Other specified disorders of ear	0.000	0.998	0.002
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.002
G96.1 Disorders of meninges, not elsewhere classified	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.998	0.002
S82.70 Multiple fractures of lower leg (closed)	0.000	0.998	0.002
D22.1 Melanocytic naevi of eyelid, including canthus	0.002	0.998	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
H91 Other hearing loss	0.000	0.998	0.002
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.998	0.002
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.998	0.002
H93.9 Disorder of ear, unspecified	0.000	0.998	0.002
Z64.0 Problems related to unwanted pregnancy	0.002	0.998	0.000
C32.0 Glottis	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.000	0.998	0.002
D47.4 Osteomyelofibrosis	0.000	0.998	0.002
H80-H83 Diseases of inner ear	0.000	0.998	0.002
C32.1 Supraglottis	0.002	0.998	0.000
Q43.8 Other specified congenital malformations of intestine	0.000	0.998	0.002
T87.5 Necrosis of amputation stump	0.002	0.998	0.000
Q28 Other congenital malformations of circulatory system	0.002	0.998	0.000
Z52 Donors of organs and tissues	0.002	0.998	0.000
H33.3 Retinal breaks without detachment	0.000	0.998	0.002
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.000	0.998	0.002
S82.6 Fracture of lateral malleolus	0.001	0.998	0.000
Z73.3 Stress, not elsewhere classified	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
Z52.3 Bone marrow donor	0.002	0.998	0.000
M25.8 Other specified joint disorders	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.998	0.002
G97.9 Postprocedural disorder of nervous system, unspecified	0.001	0.998	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.001	0.998	0.000
H74.0 Tympanosclerosis	0.000	0.998	0.002
H90.0 Conductive hearing loss, bilateral	0.000	0.998	0.002
H91.1 Presbycusis	0.000	0.998	0.002
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.002	0.998	0.000
O72.1 Other immediate postpartum haemorrhage	0.000	0.998	0.002
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.002	0.998	0.000
T87.2 Complications of other reattached body part	0.001	0.998	0.000
T87.1 Complications of reattached (part of) lower extremity	0.001	0.998	0.000
T87.0 Complications of reattached (part of) upper extremity	0.001	0.998	0.000
G91 Hydrocephalus	0.002	0.998	0.000
S72.41 Fracture of lower end of femur (open)	0.000	0.998	0.002
G70.9 Myoneural disorder, unspecified	0.000	0.998	0.001
H81.2 Vestibular neuronitis	0.000	0.998	0.002
M92.6 Juvenile osteochondrosis of tarsus	0.000	0.998	0.002
Z52.4 Kidney donor	0.002	0.998	0.000
Z73.6 Limitation of activities due to disability	0.002	0.998	0.000
H60-H62 Diseases of external ear	0.000	0.998	0.002
M25.77 Osteophyte (Ankle and foot)	0.002	0.998	0.000
S82.61 Fracture of lateral malleolus (open)	0.001	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.001	0.998	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.998	0.002
Q38 Other congenital malformations of tongue, mouth and pharynx	0.000	0.998	0.001
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.998	0.001
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.998	0.001
G73.7 Myopathy other diseases classified elsewhere	0.000	0.998	0.001
G73.6 Myopathy in metabolic diseases	0.000	0.998	0.001
G73.5 Myopathy in endocrine diseases	0.000	0.998	0.001
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.000	0.998	0.001
G73.2 Other myasthenic syndromes in neoplastic disease	0.000	0.998	0.001
G73.1 Eaton-Lambert syndrome	0.000	0.998	0.001
H91.0 Ototoxic hearing loss	0.000	0.998	0.001
I61.5 Intracerebral haemorrhage, intraventricular	0.002	0.998	0.000
S82.7 Multiple fractures of lower leg	0.000	0.998	0.001
T87.3 Neuroma of amputation stump	0.001	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
G91.3 Posttraumatic hydrocephalus, unspecified	0.001	0.998	0.000
H91.8 Other specified hearing loss	0.000	0.998	0.001
S52.70 Multiple fractures of forearm (closed)	0.000	0.998	0.001
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.001
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.002	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.001	0.998	0.000
S82.3 Fracture of lower end of tibia	0.000	0.998	0.002
Q40 Other congenital malformations of upper alimentary tract	0.000	0.998	0.001
B99-B99 Other infectious diseases	0.000	0.998	0.001
L08.8 Other specified local infections of skin and subcutaneous tissue	0.001	0.998	0.000
Z52.2 Bone donor	0.001	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.000	0.998	0.001
K70.3 Alcoholic cirrhosis of liver	0.000	0.999	0.001
L23.1 Allergic contact dermatitis due to adhesives	0.000	0.999	0.001
L73.8 Other specified follicular disorders	0.000	0.999	0.001
Q21.9 Congenital malformation of cardiac septum, unspecified	0.001	0.999	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.001	0.999	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.001	0.999	0.000
Q28.1 Other malformations of precerebral vessels	0.001	0.999	0.000
Q38.6 Other congenital malformations of mouth	0.000	0.999	0.001
S93.4 Sprain and strain of ankle	0.001	0.999	0.000
S93.5 Sprain and strain of toe(s)	0.001	0.999	0.000
T50.4 Drugs affecting uric acid metabolism	0.001	0.999	0.000
Z52.9 Donor of unspecified organ or tissue	0.001	0.999	0.000
Z52.7 Heart donor	0.001	0.999	0.000
Z52.6 Liver donor	0.001	0.999	0.000
Z52.5 Cornea donor	0.001	0.999	0.000
Z52.1 Skin donor	0.001	0.999	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.001	0.999	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.001	0.999	0.000
G91.2 Normal-pressure hydrocephalus	0.001	0.999	0.000
G91.0 Communicating hydrocephalus	0.001	0.999	0.000
H17.9 Corneal scar and opacity, unspecified	0.000	0.999	0.001
H74.1 Adhesive middle ear disease	0.000	0.999	0.001
I61.4 Intracerebral haemorrhage in cerebellum	0.001	0.999	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.001	0.999	0.000
F40 Phobic anxiety disorders	0.001	0.999	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.001	0.999	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.001	0.999	0.000
G73.0 Myasthenic syndromes in endocrine diseases	0.000	0.999	0.001
H91.3 Deaf mutism, not elsewhere classified	0.000	0.999	0.001
O71.4 Obstetric high vaginal laceration alone	0.001	0.999	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.000	0.999	0.001
Q40.1 Congenital hiatus hernia	0.000	0.999	0.001
S72.4 Fracture of lower end of femur	0.000	0.999	0.001
S93.6 Sprain and strain of other and unspecified parts of foot	0.001	0.999	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.001	0.999	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.999	0.001
Q21 Congenital malformations of cardiac septa	0.001	0.999	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.000	0.999	0.001
C74.9 Adrenal gland, unspecified	0.000	0.999	0.001
F01.9 Vascular dementia, unspecified	0.000	0.999	0.001
G91.8 Other hydrocephalus	0.001	0.999	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.999	0.001
H83.8 Other specified diseases of inner ear	0.000	0.999	0.001
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.001	0.999	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.001	0.999	0.000
D30.3 Bladder	0.000	0.999	0.001
H93.1 Tinnitus	0.000	0.999	0.001
M05.9 Seropositive rheumatoid arthritis, unspecified	0.001	0.999	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.999	0.001
Y40.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
L12.1 Cicatricial pemphigoid	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000
Q38.8 Other congenital malformations of pharynx	0.000	0.999	0.001
T40.2 Other opioids	0.000	0.999	0.001
S82.71 Multiple fractures of lower leg (open)	0.000	0.999	0.001
H11.3 Conjunctival haemorrhage	0.000	0.999	0.001
H90.2 Conductive hearing loss, unspecified	0.000	0.999	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.000	0.999	0.001
Q38.3 Other congenital malformations of tongue	0.000	0.999	0.001
Q38.2 Macroglossia	0.000	0.999	0.001
Q38.0 Congenital malformations of lips, not elsewhere classified	0.000	0.999	0.001
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.999	0.001
O61.0 Failed medical induction of labour	0.000	0.999	0.001
Q21.3 Tetralogy of Fallot	0.001	0.999	0.000
S82.11 Fracture of upper end of tibia (open)	0.000	0.999	0.001
D82.1 Di George's syndrome	0.001	0.999	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.001	0.999	0.000
H91.2 Sudden idiopathic hearing loss	0.000	0.999	0.001
I61.3 Intracerebral haemorrhage in brain stem	0.001	0.999	0.000
M21.1 Varus deformity, not elsewhere classified	0.000	0.999	0.001
Q27.3 Peripheral arteriovenous malformation	0.001	0.999	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.001	0.999	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.000	0.999	0.001
Q40.8 Other specified congenital malformations of upper alimentary tract	0.000	0.999	0.001
Q40.2 Other specified congenital malformations of stomach	0.000	0.999	0.001
Q40.0 Congenital hypertrophic pyloric stenosis	0.000	0.999	0.001
Z74.1 Need for assistance with personal care	0.001	0.999	0.000
S82 Fracture of lower leg, including ankle	0.000	0.999	0.001
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.001	0.999	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.999	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.001	0.999	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.999	0.001
M06.0 Seronegative rheumatoid arthritis	0.001	0.999	0.000
Q24.8 Other specified congenital malformations of heart	0.000	0.999	0.001
Z52.0 Blood donor	0.001	0.999	0.000
M25.82 Other specified joint disorders (Upper arm)	0.001	0.999	0.000
F40.9 Phobic anxiety disorder, unspecified	0.001	0.999	0.000
F40.8 Other phobic anxiety disorders	0.001	0.999	0.000
F40.1 Social phobias	0.001	0.999	0.000
G91.9 Hydrocephalus, unspecified	0.001	0.999	0.000
Q45 Other congenital malformations of digestive system	0.000	0.999	0.001
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.001	0.999	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.001	0.999	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.001	0.999	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.999	0.001
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.999	0.001
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.999	0.001
H62.2 Otitis externa in mycoses	0.000	0.999	0.001
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.999	0.001
H83.9 Disease of inner ear, unspecified	0.000	0.999	0.001
M11.2 Other chondrocalcinosis	0.000	0.999	0.001
Q21.4 Aortopulmonary septal defect	0.001	0.999	0.000
Q21.2 Atrioventricular septal defect	0.001	0.999	0.000
Z01.4 Gynaecological examination (general)(routine)	0.001	0.999	0.000
I61 Intracerebral haemorrhage	0.001	0.999	0.000
Q27 Other congenital malformations of peripheral vascular system	0.001	0.999	0.000
Q43 Other congenital malformations of intestine	0.000	0.999	0.001
Q42 Congenital absence, atresia and stenosis of large intestine	0.000	0.999	0.001
Q41 Congenital absence, atresia and stenosis of small intestine	0.000	0.999	0.001
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.001	0.999	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.001	0.999	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.001	0.999	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.999	0.001
G82.1 Spastic paraplegia	0.001	0.999	0.000
H74.4 Polyp of middle ear	0.000	0.999	0.001
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.999	0.000
H72 Perforation of tympanic membrane	0.000	0.999	0.001
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.001	0.999	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.999	0.001
Q25.1 Coarctation of aorta	0.001	0.999	0.000
Q45.8 Other specified congenital malformations of digestive system	0.000	0.999	0.001
S82.9 Fracture of lower leg, part unspecified	0.000	0.999	0.001
Q20-Q28 Congenital malformations of the circulatory system	0.001	0.999	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.001	0.999	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.000	0.999	0.001
Q23.1 Congenital insufficiency of aortic valve	0.001	0.999	0.000
Q25.3 Stenosis of aorta	0.001	0.999	0.000
Q38.1 Ankyloglossia	0.000	0.999	0.001
C32 Malignant neoplasm of larynx	0.001	0.999	0.000
H80 Otosclerosis	0.000	0.999	0.001
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.999	0.001
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.999	0.001
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.999	0.001
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.999	0.001
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.999	0.001
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.999	0.001
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.999	0.001
M06.08 Seronegative rheumatoid arthritis (Other)	0.001	0.999	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.001	0.999	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.001	0.999	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.999	0.001
Q38.5 Congenital malformations of palate, not elsewhere classified	0.000	0.999	0.001
Q43.3 Congenital malformations of intestinal fixation	0.000	0.999	0.001
Q45.9 Congenital malformation of digestive system, unspecified	0.000	0.999	0.001
Q45.2 Congenital pancreatic cyst	0.000	0.999	0.001
Q45.1 Annular pancreas	0.000	0.999	0.001
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.000	0.999	0.001
Q25 Congenital malformations of great arteries	0.001	0.999	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.000	0.999	0.001
M11.28 Other chondrocalcinosis (Other)	0.000	0.999	0.001
M11.27 Other chondrocalcinosis (Ankle and foot)	0.000	0.999	0.001
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.000	0.999	0.001
M11.24 Other chondrocalcinosis (Hand)	0.000	0.999	0.001
M11.23 Other chondrocalcinosis (Forearm)	0.000	0.999	0.001
M11.22 Other chondrocalcinosis (Upper arm)	0.000	0.999	0.001
M11.20 Other chondrocalcinosis (Multiple sites)	0.000	0.999	0.001
H80.0 Otosclerosis involving oval window, nonobliterative	0.000	0.999	0.001
Q27.4 Congenital phlebectasia	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations