TreeWAS – Variant ID: rs4333127

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I64 Stroke, not specified as haemorrhage or infarction	0.350	0.650	0.000
I60-I69 Cerebrovascular diseases	0.349	0.651	0.000
I63 Cerebral infarction	0.348	0.652	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.340	0.660	0.000
I65.2 Occlusion and stenosis of carotid artery	0.325	0.675	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.318	0.682	0.000
I63.9 Cerebral infarction, unspecified	0.317	0.683	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.307	0.693	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.300	0.700	0.000
I69 Sequelae of cerebrovascular disease	0.299	0.701	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.277	0.723	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.271	0.729	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.264	0.736	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.262	0.737	0.000
I62 Other nontraumatic intracranial haemorrhage	0.262	0.738	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.261	0.739	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.256	0.744	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.255	0.744	0.000
I65.1 Occlusion and stenosis of basilar artery	0.255	0.745	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.253	0.747	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.250	0.750	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.244	0.756	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.242	0.758	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.238	0.762	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.226	0.774	0.000
I61 Intracerebral haemorrhage	0.221	0.779	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.215	0.785	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.215	0.785	0.000
I68.0 Cerebral amyloid angiopathy	0.215	0.785	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.209	0.791	0.000
I63.8 Other cerebral infarction	0.203	0.797	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.197	0.803	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.194	0.806	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.194	0.806	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.194	0.806	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.192	0.808	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.185	0.815	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.184	0.815	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.183	0.817	0.000
I62.1 Nontraumatic extradural haemorrhage	0.177	0.822	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.177	0.823	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.175	0.825	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.174	0.826	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.173	0.827	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.168	0.831	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.166	0.834	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.164	0.836	0.000
I61.8 Other intracerebral haemorrhage	0.161	0.839	0.000
I60 Subarachnoid haemorrhage	0.153	0.847	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.146	0.854	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.141	0.859	0.000
I69.3 Sequelae of cerebral infarction	0.136	0.864	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.133	0.867	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.131	0.869	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.122	0.878	0.000
I60.8 Other subarachnoid haemorrhage	0.116	0.884	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.112	0.888	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.110	0.890	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.107	0.892	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.107	0.893	0.000
I67 Other cerebrovascular diseases	0.105	0.895	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.102	0.898	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.098	0.902	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.089	0.911	0.000
I67.2 Cerebral atherosclerosis	0.083	0.917	0.000
I67.8 Other specified cerebrovascular diseases	0.078	0.922	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.075	0.924	0.000
I67.5 Moyamoya disease	0.075	0.924	0.000
I67.3 Progressive vascular leukoencephalopathy	0.075	0.924	0.000
I67.4 Hypertensive encephalopathy	0.073	0.927	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.072	0.928	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.070	0.929	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.054	0.946	0.000
I67.1 Cerebral aneurysm, nonruptured	0.046	0.954	0.000
C15.9 Oesophagus, unspecified	0.027	0.973	0.000
C15 Malignant neoplasm of oesophagus	0.025	0.975	0.000
C15.4 Middle third of oesophagus	0.022	0.977	0.000
C16.9 Stomach, unspecified	0.021	0.979	0.000
C16 Malignant neoplasm of stomach	0.020	0.980	0.000
C15.3 Upper third of oesophagus	0.019	0.981	0.000
C15.1 Thoracic part of oesophagus	0.019	0.981	0.000
C16.0 Cardia	0.018	0.981	0.000
C15.0 Cervical part of oesophagus	0.018	0.982	0.000
C15.5 Lower third of oesophagus	0.018	0.982	0.000
C15.8 Overlapping lesion of oesophagus	0.018	0.982	0.000
C15.2 Abdominal part of oesophagus	0.018	0.982	0.000
C16.4 Pylorus	0.016	0.984	0.000
C16.5 Lesser curvature of stomach, unspecified	0.015	0.985	0.000
C15-C26 Malignant neoplasms of digestive organs	0.015	0.985	0.000
C16.2 Body of stomach	0.015	0.985	0.000
C16.8 Overlapping lesion of stomach	0.014	0.985	0.000
C16.3 Pyloric antrum	0.014	0.986	0.000
C16.1 Fundus of stomach	0.014	0.986	0.000
I67.9 Cerebrovascular disease, unspecified	0.013	0.987	0.000
C16.6 Greater curvature of stomach, unspecified	0.013	0.987	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.013	0.987	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.013	0.987	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.013	0.987	0.000
C23 Malignant neoplasm of gallbladder	0.012	0.988	0.000
C24.1 Ampulla of Vater	0.012	0.988	0.000
C09.9 Tonsil, unspecified	0.000	0.988	0.012
C26.0 Intestinal tract, part unspecified	0.011	0.989	0.000
C21 Malignant neoplasm of anus and anal canal	0.011	0.989	0.000
C22.9 Liver, unspecified	0.011	0.989	0.000
C24.9 Biliary tract, unspecified	0.010	0.990	0.000
C17 Malignant neoplasm of small intestine	0.010	0.990	0.000
C22.1 Intrahepatic bile duct carcinoma	0.010	0.990	0.000
C24.8 Overlapping lesion of biliary tract	0.010	0.990	0.000
C21.1 Anal canal	0.010	0.990	0.000
C24.0 Extrahepatic bile duct	0.009	0.990	0.000
C22.7 Other specified carcinomas of liver	0.009	0.991	0.000
C22.4 Other sarcomas of liver	0.009	0.991	0.000
C22.3 Angiosarcoma of liver	0.009	0.991	0.000
C22.2 Hepatoblastoma	0.009	0.991	0.000
C26.8 Overlapping lesion of digestive system	0.009	0.991	0.000
C26.1 Spleen	0.009	0.991	0.000
C22.0 Liver cell carcinoma	0.009	0.991	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.991	0.009
C26.9 Ill-defined sites within the digestive system	0.009	0.991	0.000
C09 Malignant neoplasm of tonsil	0.000	0.991	0.009
C21.2 Cloacogenic zone	0.008	0.992	0.000
D13.1 Stomach	0.000	0.992	0.008
C17.0 Duodenum	0.008	0.992	0.000
C17.9 Small intestine, unspecified	0.007	0.992	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.007	0.992	0.000
C17.8 Overlapping lesion of small intestine	0.007	0.992	0.000
C17.3 Meckel's diverticulum	0.007	0.992	0.000
L60.0 Ingrowing nail	0.000	0.993	0.007
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.993	0.007
C25 Malignant neoplasm of pancreas	0.007	0.993	0.000
C17.1 Jejunum	0.007	0.993	0.000
C01 Malignant neoplasm of base of tongue	0.000	0.993	0.007
C07 Malignant neoplasm of parotid gland	0.000	0.993	0.007
C17.2 Ileum	0.006	0.993	0.000
C09.8 Overlapping lesion of tonsil	0.000	0.993	0.006
C21.0 Anus, unspecified	0.006	0.994	0.000
C09.0 Tonsillar fossa	0.000	0.994	0.006
C11 Malignant neoplasm of nasopharynx	0.000	0.994	0.006
I27.0 Primary pulmonary hypertension	0.006	0.994	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.000	0.994	0.006
H81.0 Meniere's disease	0.006	0.994	0.000
C10 Malignant neoplasm of oropharynx	0.000	0.994	0.006
C06 Malignant neoplasm of other and unspecified parts of mouth	0.000	0.994	0.006
C25.4 Endocrine pancreas	0.006	0.994	0.000
C04 Malignant neoplasm of floor of mouth	0.000	0.994	0.006
C25.7 Other parts of pancreas	0.005	0.994	0.000
C03 Malignant neoplasm of gum	0.000	0.994	0.005
I27 Other pulmonary heart diseases	0.006	0.994	0.000
C05 Malignant neoplasm of palate	0.000	0.994	0.005
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.995	0.005
C12 Malignant neoplasm of pyriform sinus	0.000	0.995	0.005
C25.8 Overlapping lesion of pancreas	0.005	0.995	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.995	0.005
C25.3 Pancreatic duct	0.005	0.995	0.000
C25.2 Tail of pancreas	0.005	0.995	0.000
C11.9 Nasopharynx, unspecified	0.000	0.995	0.005
C11.1 Posterior wall of nasopharynx	0.000	0.995	0.005
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.995	0.005
C00 Malignant neoplasm of lip	0.000	0.995	0.005
I27.8 Other specified pulmonary heart diseases	0.005	0.995	0.000
I27.9 Pulmonary heart disease, unspecified	0.005	0.995	0.000
O47.0 False labour before 37 completed weeks of gestation	0.005	0.995	0.000
H81 Disorders of vestibular function	0.005	0.995	0.000
C13 Malignant neoplasm of hypopharynx	0.000	0.995	0.005
C25.1 Body of pancreas	0.005	0.995	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.005	0.995	0.000
C11.8 Overlapping lesion of nasopharynx	0.000	0.995	0.005
C11.3 Anterior wall of nasopharynx	0.000	0.995	0.005
C11.2 Lateral wall of nasopharynx	0.000	0.995	0.005
C11.0 Superior wall of nasopharynx	0.000	0.995	0.005
O43.8 Other placental disorders	0.005	0.995	0.000
O43 Placental disorders	0.005	0.995	0.000
C10.9 Oropharynx, unspecified	0.000	0.995	0.005
C06.2 Retromolar area	0.000	0.995	0.004
R04.2 Haemoptysis	0.005	0.995	0.000
C05.0 Hard palate	0.000	0.995	0.004
C03.9 Gum, unspecified	0.000	0.995	0.004
C03.0 Upper gum	0.000	0.995	0.004
C06.0 Cheek mucosa	0.000	0.995	0.004
C04.9 Floor of mouth, unspecified	0.000	0.996	0.004
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.004	0.996	0.000
O47 False labour	0.004	0.996	0.000
C02.2 Ventral surface of tongue	0.000	0.996	0.004
O48 Prolonged pregnancy	0.004	0.996	0.000
C10.8 Overlapping lesion of oropharynx	0.000	0.996	0.004
C10.4 Branchial cleft	0.000	0.996	0.004
C10.3 Posterior wall of oropharynx	0.000	0.996	0.004
C10.2 Lateral wall of oropharynx	0.000	0.996	0.004
C10.1 Anterior surface of epiglottis	0.000	0.996	0.004
C10.0 Vallecula	0.000	0.996	0.004
C14.0 Pharynx, unspecified	0.000	0.996	0.004
C04.0 Anterior floor of mouth	0.000	0.996	0.004
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.000	0.996	0.004
C06.1 Vestibule of mouth	0.000	0.996	0.004
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.000	0.996	0.004
C04.8 Overlapping lesion of floor of mouth	0.000	0.996	0.004
C04.1 Lateral floor of mouth	0.000	0.996	0.004
C05.1 Soft palate	0.000	0.996	0.004
I27.1 Kyphoscoliotic heart disease	0.004	0.996	0.000
C25.0 Head of pancreas	0.004	0.996	0.000
C05.8 Overlapping lesion of palate	0.000	0.996	0.004
C05.2 Uvula	0.000	0.996	0.004
H81.2 Vestibular neuronitis	0.004	0.996	0.000
H81.3 Other peripheral vertigo	0.004	0.996	0.000
C14.2 Waldeyer's ring	0.000	0.996	0.004
H81.1 Benign paroxysmal vertigo	0.004	0.996	0.000
C06.9 Mouth, unspecified	0.000	0.996	0.004
I27.2 Other secondary pulmonary hypertension	0.004	0.996	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.000	0.996	0.004
C02.8 Overlapping lesion of tongue	0.000	0.996	0.004
C02.0 Dorsal surface of tongue	0.000	0.996	0.004
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.000	0.996	0.004
H81.4 Vertigo of central origin	0.004	0.996	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.996	0.004
C03.1 Lower gum	0.000	0.996	0.004
C08.8 Overlapping lesion of major salivary glands	0.000	0.996	0.004
C08.1 Sublingual gland	0.000	0.996	0.004
O32 Maternal care for known or suspected malpresentation of foetus	0.004	0.996	0.000
C00.8 Overlapping lesion of lip	0.000	0.996	0.004
C00.6 Commissure of lip	0.000	0.996	0.004
C00.5 Lip, unspecified, inner aspect	0.000	0.996	0.004
C00.4 Lower lip, inner aspect	0.000	0.996	0.004
C00.3 Upper lip, inner aspect	0.000	0.996	0.004
C00.2 External lip, unspecified	0.000	0.996	0.004
C02.1 Border of tongue	0.000	0.996	0.004
O33 Maternal care for known or suspected disproportion	0.004	0.996	0.000
C00.0 External upper lip	0.000	0.996	0.004
D13.0 Oesophagus	0.000	0.996	0.004
H80.9 Otosclerosis, unspecified	0.004	0.996	0.000
O43.0 Placental transfusion syndromes	0.004	0.996	0.000
O31 Complications specific to multiple gestation	0.004	0.996	0.000
C05.9 Palate, unspecified	0.000	0.996	0.004
H25.0 Senile incipient cataract	0.000	0.996	0.004
O43.1 Malformation of placenta	0.004	0.996	0.000
C00.1 External lower lip	0.000	0.996	0.004
O40 Polyhydramnios	0.004	0.996	0.000
C02.9 Tongue, unspecified	0.000	0.996	0.004
C02.4 Lingual tonsil	0.000	0.996	0.004
O41 Other disorders of amniotic fluid and membranes	0.004	0.996	0.000
C13.8 Overlapping lesion of hypopharynx	0.000	0.996	0.003
C13.2 Posterior wall of hypopharynx	0.000	0.996	0.003
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.000	0.996	0.003
N85.0 Endometrial glandular hyperplasia	0.004	0.996	0.000
C08.9 Major salivary gland, unspecified	0.000	0.996	0.003
C08.0 Submandibular gland	0.000	0.996	0.003
S81.0 Open wound of knee	0.004	0.996	0.000
D48.6 Breast	0.000	0.996	0.004
O32.2 Maternal care for transverse and oblique lie	0.004	0.996	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.996	0.004
C00.9 Lip, unspecified	0.000	0.996	0.003
C13.0 Postcricoid region	0.000	0.996	0.003
C25.9 Pancreas, unspecified	0.004	0.996	0.000
O43.9 Placental disorder, unspecified	0.004	0.996	0.000
O43.2 Morbidly adherent placenta	0.003	0.996	0.000
O42.9 Premature rupture of membranes, unspecified	0.004	0.996	0.000
H81.9 Disorder of vestibular function, unspecified	0.003	0.996	0.000
O44 Placenta praevia	0.003	0.996	0.000
O45 Premature separation of placenta [abruptio placentae]	0.003	0.996	0.000
L60 Nail disorders	0.000	0.996	0.003
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.004	0.996	0.000
D13.9 Ill-defined sites within the digestive system	0.000	0.997	0.003
D13.4 Liver	0.000	0.997	0.003
L60.9 Nail disorder, unspecified	0.000	0.997	0.003
O30 Multiple gestation	0.003	0.997	0.000
D13.3 Other and unspecified parts of small intestine	0.000	0.997	0.003
O42 Premature rupture of membranes	0.003	0.997	0.000
O33.9 Maternal care for disproportion, unspecified	0.003	0.997	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.003	0.997	0.000
H81.8 Other disorders of vestibular function	0.003	0.997	0.000
C13.9 Hypopharynx, unspecified	0.000	0.997	0.003
O31.8 Other complications specific to multiple gestation	0.003	0.997	0.000
O32.0 Maternal care for unstable lie	0.003	0.997	0.000
H80 Otosclerosis	0.003	0.997	0.000
O47.9 False labour, unspecified	0.003	0.997	0.000
I34.1 Mitral (valve) prolapse	0.003	0.997	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.003	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.003	0.997	0.000
D13.7 Endocrine pancreas	0.000	0.997	0.003
O32.8 Maternal care for other malpresentation of foetus	0.003	0.997	0.000
O32.1 Maternal care for breech presentation	0.003	0.997	0.000
O41.0 Oligohydramnios	0.003	0.997	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.003	0.997	0.000
O32.3 Maternal care for face, brow and chin presentation	0.003	0.997	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.003	0.997	0.000
O32.6 Maternal care for compound presentation	0.003	0.997	0.000
O33.8 Maternal care for disproportion of other origin	0.003	0.997	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.003	0.997	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.003	0.997	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.003	0.997	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.003	0.997	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.003	0.997	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.003	0.997	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.003	0.997	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.003	0.997	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.003	0.997	0.000
O31.0 Papyraceous foetus	0.003	0.997	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.003	0.997	0.000
D13.6 Pancreas	0.000	0.997	0.003
L60.3 Nail dystrophy	0.000	0.997	0.003
O30.1 Triplet pregnancy	0.003	0.997	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.003	0.997	0.000
O41.1 Infection of amniotic sac and membranes	0.003	0.997	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.003	0.997	0.000
H80-H83 Diseases of inner ear	0.003	0.997	0.000
D13.5 Extrahepatic bile ducts	0.000	0.997	0.003
D48.0 Bone and articular cartilage	0.000	0.997	0.003
I28 Other diseases of pulmonary vessels	0.003	0.997	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.003	0.997	0.000
O45.9 Premature separation of placenta, unspecified	0.003	0.997	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.997	0.003
Chapter IX Diseases of the circulatory system	0.003	0.997	0.000
O45.8 Other premature separation of placenta	0.003	0.997	0.000
O45.0 Premature separation of placenta with coagulation defect	0.003	0.997	0.000
L60.5 Yellow nail syndrome	0.000	0.997	0.003
L60.4 Beau's lines	0.000	0.997	0.003
L60.1 Onycholysis	0.000	0.997	0.003
O30.9 Multiple gestation, unspecified	0.003	0.997	0.000
O30.8 Other multiple gestation	0.003	0.997	0.000
O30.2 Quadruplet pregnancy	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.003	0.997	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.003	0.997	0.000
H80.2 Cochlear otosclerosis	0.002	0.997	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.002	0.997	0.000
M79.67 Pain in limb (Ankle and foot)	0.000	0.997	0.003
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
O32.4 Maternal care for high head at term	0.002	0.997	0.000
O46.8 Other antepartum haemorrhage	0.003	0.997	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.002	0.997	0.000
D48.7 Other specified sites	0.000	0.997	0.003
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.997	0.003
H80.8 Other otosclerosis	0.002	0.997	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.002	0.997	0.000
I05-I09 Chronic rheumatic heart diseases	0.003	0.997	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.002	0.997	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.002	0.997	0.000
D48.5 Skin	0.000	0.998	0.002
L60.2 Onychogryphosis	0.000	0.998	0.002
I28.9 Disease of pulmonary vessels, unspecified	0.002	0.998	0.000
I08 Multiple valve diseases	0.002	0.998	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.002	0.998	0.000
S81 Open wound of lower leg	0.002	0.998	0.000
D13.2 Duodenum	0.000	0.998	0.002
G93.3 Postviral fatigue syndrome	0.002	0.998	0.000
H16.0 Corneal ulcer	0.000	0.998	0.002
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.002	0.998	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.002	0.998	0.000
O34.4 Maternal care for other abnormalities of cervix	0.002	0.998	0.000
I28.1 Aneurysm of pulmonary artery	0.002	0.998	0.000
N41.1 Chronic prostatitis	0.002	0.998	0.000
O30.0 Twin pregnancy	0.002	0.998	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.002	0.998	0.000
D48.4 Peritoneum	0.000	0.998	0.002
O34.3 Maternal care for cervical incompetence	0.002	0.998	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.998	0.002
I28.8 Other specified diseases of pulmonary vessels	0.002	0.998	0.000
D48.3 Retroperitoneum	0.000	0.998	0.002
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
I00-I02 Acute rheumatic fever	0.002	0.998	0.000
I09 Other rheumatic heart diseases	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
I08.9 Multiple valve disease, unspecified	0.002	0.998	0.000
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
O34.6 Maternal care for abnormality of vagina	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
O34.0 Maternal care for congenital malformation of uterus	0.002	0.998	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.000	0.998	0.002
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.998	0.002
I89.0 Lymphoedema, not elsewhere classified	0.000	0.998	0.002
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
O80.0 Spontaneous vertex delivery	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
O34.1 Maternal care for tumour of corpus uteri	0.002	0.998	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.002	0.998	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.002	0.998	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.002	0.998	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.002	0.998	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.002	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.002	0.998	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.002	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.002	0.998	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.002	0.998	0.000
O36 Maternal care for other known or suspected foetal problems	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
I09.9 Rheumatic heart disease, unspecified	0.002	0.998	0.000
I06 Rheumatic aortic valve diseases	0.002	0.998	0.000
J31.0 Chronic rhinitis	0.002	0.998	0.000
I34 Nonrheumatic mitral valve disorders	0.002	0.998	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
L60.8 Other nail disorders	0.000	0.998	0.002
A49.9 Bacterial infection, unspecified	0.000	0.998	0.002
I08.8 Other multiple valve diseases	0.002	0.998	0.000
S81.7 Multiple open wounds of lower leg	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
O36.3 Maternal care for signs of foetal hypoxia	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
I09.8 Other specified rheumatic heart diseases	0.002	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.002	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.002	0.998	0.000
I09.0 Rheumatic myocarditis	0.002	0.998	0.000
R04.8 Haemorrhage from other sites in respiratory passages	0.002	0.998	0.000
I02 Rheumatic chorea	0.002	0.998	0.000
I01 Rheumatic fever with heart involvement	0.002	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.002	0.998	0.000
I07.8 Other tricuspid valve diseases	0.002	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.002	0.998	0.000
I07.0 Tricuspid stenosis	0.002	0.998	0.000
T93.2 Sequelae of other fractures of lower limb	0.002	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.002	0.998	0.000
I00 Rheumatic fever without mention of heart involvement	0.002	0.998	0.000
O36.6 Maternal care for excessive foetal growth	0.002	0.998	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.002	0.998	0.000
K86.2 Cyst of pancreas	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
O36.4 Maternal care for intra-uterine death	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.002	0.998	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.998	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.002	0.998	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.998	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.002	0.998	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.998	0.000
I34.0 Mitral (valve) insufficiency	0.002	0.998	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.002	0.998	0.000
R04 Haemorrhage from respiratory passages	0.002	0.998	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.002	0.998	0.000
L03.0 Cellulitis of finger and toe	0.002	0.998	0.000
O36.2 Maternal care for hydrops foetalis	0.002	0.998	0.000
H16 Keratitis	0.000	0.998	0.002
T93 Sequelae of injuries of lower limb	0.002	0.998	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.001	0.998	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
D04.7 Skin of lower limb, including hip	0.000	0.998	0.002
H16.9 Keratitis, unspecified	0.000	0.998	0.002
I06.8 Other rheumatic aortic valve diseases	0.001	0.998	0.000
O36.1 Maternal care for other isoimmunisation	0.002	0.998	0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.998	0.002
A49.8 Other bacterial infections of unspecified site	0.000	0.998	0.002
H16.2 Keratoconjunctivitis	0.000	0.998	0.002
J06.9 Acute upper respiratory infection, unspecified	0.002	0.998	0.000
C20 Malignant neoplasm of rectum	0.002	0.998	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.001	0.998	0.000
I01.8 Other acute rheumatic heart disease	0.001	0.998	0.000
I01.2 Acute rheumatic myocarditis	0.001	0.998	0.000
I01.1 Acute rheumatic endocarditis	0.001	0.998	0.000
I01.0 Acute rheumatic pericarditis	0.001	0.998	0.000
I02.9 Rheumatic chorea without heart involvement	0.001	0.998	0.000
I02.0 Rheumatic chorea with heart involvement	0.001	0.998	0.000
I06.1 Rheumatic aortic insufficiency	0.001	0.998	0.000
T51.9 Alcohol, unspecified	0.000	0.998	0.002
G24.9 Dystonia, unspecified	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.000	0.998	0.001
N85.1 Endometrial adenomatous hyperplasia	0.000	0.998	0.002
K86.8 Other specified diseases of pancreas	0.002	0.998	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.001	0.998	0.000
H83 Other diseases of inner ear	0.001	0.998	0.000
K86.3 Pseudocyst of pancreas	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.002	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.001	0.998	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.002	0.998	0.000
R04.9 Haemorrhage from respiratory passages, unspecified	0.001	0.998	0.000
H16.8 Other keratitis	0.000	0.998	0.001
I05.2 Mitral stenosis with insufficiency	0.001	0.998	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.001	0.998	0.000
I26 Pulmonary embolism	0.001	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.001	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.001	0.998	0.000
O46.9 Antepartum haemorrhage, unspecified	0.001	0.998	0.000
R04.1 Haemorrhage from throat	0.001	0.998	0.000
T91.1 Sequelae of fracture of spine	0.001	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.001	0.998	0.000
A49 Bacterial infection of unspecified site	0.000	0.998	0.001
T91 Sequelae of injuries of neck and trunk	0.001	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.001	0.999	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.001	0.999	0.000
Z93.6 Other artificial openings of urinary tract status	0.000	0.999	0.001
D39.1 Ovary	0.000	0.999	0.001
H16.3 Interstitial and deep keratitis	0.000	0.999	0.001
I05.8 Other mitral valve diseases	0.001	0.999	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.001	0.999	0.000
H49.2 Sixth [abducent] nerve palsy	0.000	0.999	0.001
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.001	0.999	0.000
T93.1 Sequelae of fracture of femur	0.001	0.999	0.000
H16.4 Corneal neovascularisation	0.000	0.999	0.001
N28.1 Cyst of kidney, acquired	0.001	0.999	0.000
H83.8 Other specified diseases of inner ear	0.001	0.999	0.000
H83.2 Labyrinthine dysfunction	0.001	0.999	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.001	0.999	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.001	0.999	0.000
I78 Diseases of capillaries	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations