TreeWAS – Variant ID: rs4452638

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
E05.9 Thyrotoxicosis, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	1.000	0.000	0.000
E10 Insulin-dependent diabetes mellitus	1.000	0.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	1.000	0.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
E83.1 Disorders of iron metabolism	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	1.000	0.000	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	1.000	0.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000	0.000
E03 Other hypothyroidism	1.000	0.000	0.000
D64.9 Anaemia, unspecified	1.000	0.000	0.000
E10.9 Without complications	1.000	0.000	0.000
N40 Hyperplasia of prostate	0.000	0.000	1.000
R31 Unspecified haematuria	0.000	0.000	1.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	1.000	0.000	0.000
E16.2 Hypoglycaemia, unspecified	1.000	0.000	0.000
E16 Other disorders of pancreatic internal secretion	1.000	0.000	0.000
M20-M25 Other joint disorders	1.000	0.000	0.000
D64 Other anaemias	1.000	0.000	0.000
D60-D64 Aplastic and other anaemias	1.000	0.000	0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.001	0.999
H30-H36 Disorders of choroid and retina	0.997	0.003	0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene	0.000	0.005	0.995
K40 Inguinal hernia	0.000	0.005	0.995
K44 Diaphragmatic hernia	0.001	0.005	0.994
K90 Intestinal malabsorption	0.994	0.006	0.000
K40-K46 Hernia	0.003	0.007	0.990
M35 Other systemic involvement of connective tissue	0.992	0.008	0.000
E14 Unspecified diabetes mellitus	0.991	0.009	0.000
M05-M14 Inflammatory polyarthropathies	0.990	0.010	0.000
M35.0 Sicca syndrome [Sjogren]	0.988	0.012	0.000
E11 Non-insulin-dependent diabetes mellitus	0.987	0.013	0.000
M31 Other necrotising vasculopathies	0.976	0.024	0.000
E20-E35 Disorders of other endocrine glands	0.975	0.025	0.000
H43-H45 Disorders of vitreous body and globe	0.974	0.026	0.000
E27 Other disorders of adrenal gland	0.968	0.032	0.000
Chapter XI Diseases of the digestive system	0.957	0.033	0.010
E05.0 Thyrotoxicosis with diffuse goitre	0.966	0.034	0.000
H34 Retinal vascular occlusions	0.966	0.034	0.000
N30-N39 Other diseases of urinary system	0.000	0.034	0.966
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.965	0.035	0.000
K90-K93 Other diseases of the digestive system	0.959	0.036	0.005
H36 Retinal disorders in diseases classified elsewhere	0.964	0.036	0.000
E11.5 With peripheral circulatory complications	0.964	0.036	0.000
D50-D53 Nutritional anaemias	0.963	0.037	0.000
C43 Malignant melanoma of skin	0.962	0.038	0.000
N32.0 Bladder-neck obstruction	0.000	0.038	0.962
N39 Other disorders of urinary system	0.000	0.038	0.962
E27.1 Primary adrenocortical insufficiency	0.961	0.039	0.000
N32 Other disorders of bladder	0.000	0.039	0.961
H46-H48 Disorders of optic nerve and visual pathways	0.960	0.040	0.000
Chapter II Neoplasms	0.960	0.040	0.000
H43 Disorders of vitreous body	0.960	0.040	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.000	0.042	0.958
C43-C44 Melanoma and other malignant neoplasms of skin	0.958	0.042	0.000
S40-S49 Injuries to the shoulder and upper arm	0.957	0.043	0.000
M31.6 Other giant cell arteritis	0.955	0.045	0.000
D80-D89 Certain disorders involving the immune mechanism	0.949	0.051	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.948	0.052	0.000
N39.8 Other specified disorders of urinary system	0.000	0.052	0.948
S46 Injury of muscle and tendon at shoulder and upper arm level	0.948	0.052	0.000
E10.3 With ophthalmic complications	0.948	0.052	0.000
M34 Systemic sclerosis	0.947	0.053	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.946	0.054	0.000
H43.1 Vitreous haemorrhage	0.946	0.054	0.000
S90-S99 Injuries to the ankle and foot	0.945	0.055	0.000
D50 Iron deficiency anaemia	0.945	0.055	0.000
E10.2 With renal complications	0.943	0.057	0.000
H36.0 Diabetic retinopathy	0.940	0.060	0.000
E14.3 With ophthalmic complications	0.940	0.060	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.936	0.064	0.000
E11.3 With ophthalmic complications	0.934	0.066	0.000
M07 Psoriatic and enteropathic arthropathies	0.931	0.068	0.000
K70-K77 Diseases of liver	0.929	0.070	0.001
Chapter XX External causes of morbidity and mortality	0.929	0.071	0.000
E10.1 With ketoacidosis	0.925	0.075	0.000
E14.9 Without complications	0.924	0.076	0.000
K75 Other inflammatory liver diseases	0.924	0.076	0.000
N39.0 Urinary tract infection, site not specified	0.000	0.076	0.924
K75.4 Autoimmune hepatitis	0.918	0.082	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.918	0.082	0.000
D50.8 Other iron deficiency anaemias	0.916	0.084	0.000
M60-M63 Disorders of muscles	0.916	0.084	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.916	0.084	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.913	0.087	0.000
E11.9 Without complications	0.913	0.087	0.000
D86 Sarcoidosis	0.908	0.092	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.901	0.099	0.000
M24 Other specific joint derangements	0.901	0.099	0.000
N36 Other disorders of urethra	0.000	0.101	0.899
M10 Gout	0.898	0.102	0.000
H34.2 Other retinal artery occlusions	0.896	0.104	0.000
M11 Other crystal arthropathies	0.896	0.104	0.000
K90.9 Intestinal malabsorption, unspecified	0.895	0.105	0.000
D00-D09 In situ neoplasms	0.895	0.105	0.000
C43.5 Malignant melanoma of trunk	0.894	0.106	0.000
S20-S29 Injuries to the thorax	0.893	0.107	0.000
S80-S89 Injuries to the knee and lower leg	0.892	0.108	0.000
M07.3 Other psoriatic arthropathies	0.889	0.111	0.000
D04 Carcinoma in situ of skin	0.889	0.111	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.886	0.114	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.885	0.115	0.000
N39.9 Disorder of urinary system, unspecified	0.000	0.115	0.885
D50.9 Iron deficiency anaemia, unspecified	0.885	0.115	0.000
C43.4 Malignant melanoma of scalp and neck	0.885	0.115	0.000
W20-W49 Exposure to inanimate mechanical forces	0.882	0.118	0.000
L20-L30 Dermatitis and eczema	0.882	0.118	0.000
L50-L54 Urticaria and erythema	0.881	0.119	0.000
N40-N51 Diseases of male genital organs	0.000	0.122	0.878
H35 Other retinal disorders	0.878	0.122	0.000
S80 Superficial injury of lower leg	0.876	0.124	0.000
K35-K38 Diseases of appendix	0.874	0.124	0.002
E50-E64 Other nutritional deficiencies	0.875	0.125	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.875	0.125	0.000
N34 Urethritis and urethral syndrome	0.000	0.126	0.874
H34.8 Other retinal vascular occlusions	0.872	0.128	0.000
D86.9 Sarcoidosis, unspecified	0.870	0.130	0.000
Chapter IX Diseases of the circulatory system	0.866	0.134	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.865	0.135	0.000
I73 Other peripheral vascular diseases	0.865	0.135	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.864	0.136	0.000
M15-M19 Arthrosis	0.863	0.137	0.000
L40-L45 Papulosquamous disorders	0.860	0.140	0.000
W22 Striking against or struck by other objects	0.859	0.141	0.000
M70-M79 Other soft tissue disorders	0.858	0.142	0.000
I73.9 Peripheral vascular disease, unspecified	0.856	0.144	0.000
S92 Fracture of foot, except ankle	0.855	0.145	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.851	0.149	0.000
M72 Fibroblastic disorders	0.851	0.149	0.000
M17 Gonarthrosis [arthrosis of knee]	0.850	0.150	0.000
S80.0 Contusion of knee	0.847	0.153	0.000
K35 Acute appendicitis	0.847	0.153	0.000
M62 Other disorders of muscle	0.846	0.154	0.000
H35.8 Other specified retinal disorders	0.845	0.155	0.000
K72 Hepatic failure, not elsewhere classified	0.843	0.156	0.000
M34.1 CR(E)ST syndrome	0.842	0.158	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.841	0.159	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.840	0.160	0.000
E10.7 With multiple complications	0.839	0.161	0.000
S21 Open wound of thorax	0.837	0.163	0.000
Chapter XIV Diseases of the genitourinary system	0.000	0.164	0.836
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.836	0.164	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.835	0.165	0.000
S93.1 Dislocation of toe(s)	0.835	0.165	0.000
E10.4 With neurological complications	0.835	0.165	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.834	0.166	0.000
C43.9 Malignant melanoma of skin, unspecified	0.834	0.166	0.000
L30 Other dermatitis	0.834	0.166	0.000
H25-H28 Disorders of lens	0.833	0.167	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.832	0.168	0.000
M11.2 Other chondrocalcinosis	0.828	0.172	0.000
N30 Cystitis	0.000	0.172	0.828
E10.8 With unspecified complications	0.827	0.172	0.000
S80.8 Other superficial injuries of lower leg	0.825	0.175	0.000
D04.5 Skin of trunk	0.825	0.175	0.000
L43 Lichen planus	0.818	0.182	0.000
H53-H54 Visual disturbances and blindness	0.818	0.182	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.816	0.184	0.000
L52 Erythema nodosum	0.815	0.185	0.000
K75.9 Inflammatory liver disease, unspecified	0.814	0.185	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.814	0.186	0.000
I77 Other disorders of arteries and arterioles	0.811	0.189	0.000
E10.5 With peripheral circulatory complications	0.811	0.189	0.000
M34.9 Systemic sclerosis, unspecified	0.809	0.191	0.000
K73 Chronic hepatitis, not elsewhere classified	0.808	0.192	0.001
D55-D59 Haemolytic anaemias	0.807	0.193	0.000
D04.7 Skin of lower limb, including hip	0.807	0.193	0.000
M22 Disorders of patella	0.806	0.194	0.000
C07 Malignant neoplasm of parotid gland	0.805	0.195	0.000
C81 Hodgkin's disease	0.805	0.195	0.000
K35.9 Acute appendicitis, unspecified	0.805	0.195	0.000
E23 Hypofunction and other disorders of pituitary gland	0.804	0.196	0.000
M17.0 Primary gonarthrosis, bilateral	0.802	0.198	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.801	0.199	0.000
E14.6 With other specified complications	0.801	0.199	0.000
N42 Other disorders of prostate	0.000	0.200	0.800
C04 Malignant neoplasm of floor of mouth	0.797	0.202	0.000
M17.1 Other primary gonarthrosis	0.797	0.203	0.000
N34.2 Other urethritis	0.000	0.203	0.797
S49.9 Unspecified injury of shoulder and upper arm	0.797	0.203	0.000
V10-V19 Pedal cyclist injured in transport accident	0.797	0.203	0.000
H46 Optic neuritis	0.796	0.204	0.000
S92.3 Fracture of metatarsal bone	0.796	0.204	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.795	0.205	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.795	0.205	0.000
W22.9 Unspecified place	0.795	0.205	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.794	0.206	0.000
X20-X29 Contact with venomous animals and plants	0.793	0.207	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.788	0.212	0.000
N36.2 Urethral caruncle	0.000	0.212	0.788
N36.0 Urethral fistula	0.000	0.213	0.787
H47.3 Other disorders of optic disk	0.787	0.213	0.000
S20 Superficial injury of thorax	0.785	0.215	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.785	0.215	0.000
L10-L14 Bullous disorders	0.785	0.215	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.785	0.215	0.000
M06 Other rheumatoid arthritis	0.782	0.218	0.000
D04.2 Skin of ear and external auricular canal	0.781	0.219	0.000
L43.9 Lichen planus, unspecified	0.781	0.219	0.000
H35.4 Peripheral retinal degeneration	0.780	0.220	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.779	0.221	0.000
C02.1 Border of tongue	0.778	0.222	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.777	0.223	0.000
N30.2 Other chronic cystitis	0.000	0.223	0.777
T20-T25 Burns and corrosions of external body surface, specified by site	0.777	0.223	0.000
E14.2 Withrenal complications	0.776	0.224	0.000
M10.0 Idiopathic gout	0.775	0.225	0.000
C13 Malignant neoplasm of hypopharynx	0.774	0.226	0.000
H43.9 Disorder of vitreous body, unspecified	0.773	0.227	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.772	0.228	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.772	0.228	0.000
V20-V29 Motorcycle rider injured in transport accident	0.771	0.229	0.000
H47.2 Optic atrophy	0.771	0.229	0.000
D61 Other aplastic anaemias	0.771	0.229	0.000
M33 Dermatopolymyositis	0.770	0.229	0.000
L27 Dermatitis due to substances taken internally	0.770	0.230	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.770	0.230	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.768	0.232	0.000
T79-T79 Certain early complications of trauma	0.767	0.233	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.000	0.235	0.765
X58-X59 Accidental exposure to other and unspecified factors	0.765	0.235	0.000
S46.3 Injury of muscle and tendon of triceps	0.764	0.236	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.764	0.236	0.000
M65-M68 Disorders of synovium and tendon	0.763	0.237	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.762	0.238	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.762	0.238	0.000
C02.9 Tongue, unspecified	0.762	0.238	0.000
M10.9 Gout, unspecified	0.762	0.238	0.000
V01-V09 Pedestrian injured in transport accident	0.761	0.239	0.000
S93.0 Dislocation of ankle joint	0.758	0.242	0.000
E11.6 With other specified complications	0.758	0.242	0.000
M34.8 Other forms of systemic sclerosis	0.758	0.242	0.000
E40-E46 Malnutrition	0.758	0.242	0.000
N32.8 Other specified disorders of bladder	0.000	0.242	0.758
M62.8 Other specified disorders of muscle	0.757	0.243	0.000
M35.2 Behcet's disease	0.756	0.244	0.000
E10.0 With coma	0.756	0.244	0.000
E14.8 With unspecified complications	0.755	0.245	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.754	0.246	0.000
S92.30 Fracture of metatarsal bone (closed)	0.754	0.246	0.000
E53 Deficiency of other B group vitamins	0.753	0.247	0.000
H30 Chorioretinal inflammation	0.752	0.248	0.000
M14 Arthropathies in other diseases classified elsewhere	0.751	0.249	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.749	0.251	0.000
W50-W64 Exposure to animate mechanical forces	0.748	0.252	0.000
E16.1 Other hypoglycaemia	0.746	0.254	0.000
I77.1 Stricture of artery	0.746	0.254	0.000
I74 Arterial embolism and thrombosis	0.746	0.254	0.000
K75.8 Other specified inflammatory liver diseases	0.745	0.255	0.000
D84 Other immunodeficiencies	0.744	0.255	0.000
L30.9 Dermatitis, unspecified	0.744	0.256	0.000
N36.3 Prolapsed urethral mucosa	0.000	0.256	0.744
E10.6 With other specified complications	0.743	0.257	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.743	0.257	0.000
X00-X09 Exposure to smoke, fire and flames	0.743	0.257	0.000
K72.0 Acute and subacute hepatic failure	0.742	0.258	0.000
M00-M03 Infectious arthropathies	0.742	0.258	0.000
L30.8 Other specified dermatitis	0.742	0.258	0.000
H31 Other disorders of choroid	0.741	0.259	0.000
W75-W84 Other accidental threats to breathing	0.741	0.259	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.259	0.741
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.262	0.738
Q38-Q45 Other congenital malformations of the digestive system	0.737	0.263	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.736	0.264	0.000
C05 Malignant neoplasm of palate	0.736	0.264	0.000
C03 Malignant neoplasm of gum	0.735	0.265	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.734	0.266	0.000
W22.5 Trade and service area	0.733	0.267	0.000
S21.9 Open wound of thorax, part unspecified	0.733	0.267	0.000
L50 Urticaria	0.733	0.267	0.000
I60-I69 Cerebrovascular diseases	0.731	0.269	0.000
X10-X19 Contact with heat and hot substances	0.731	0.269	0.000
N48 Other disorders of penis	0.000	0.269	0.731
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.001	0.270	0.730
S21.1 Open wound of front wall of thorax	0.728	0.272	0.000
M12 Other specific arthropathies	0.728	0.272	0.000
C01 Malignant neoplasm of base of tongue	0.726	0.274	0.000
E13 Other specified diabetes mellitus	0.725	0.275	0.000
M17.9 Gonarthrosis, unspecified	0.723	0.277	0.000
M80-M85 Disorders of bone density and structure	0.722	0.278	0.000
D86.3 Sarcoidosis of skin	0.722	0.278	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.722	0.278	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.721	0.279	0.000
W22.3 Sports and athletics area	0.721	0.279	0.000
M06.9 Rheumatoid arthritis, unspecified	0.721	0.279	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.720	0.279	0.000
M32 Systemic lupus erythematosus	0.720	0.280	0.000
C11 Malignant neoplasm of nasopharynx	0.719	0.280	0.000
H26 Other cataract	0.720	0.280	0.000
H43.2 Crystalline deposits in vitreous body	0.719	0.281	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.718	0.282	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.717	0.283	0.000
E00 Congenital iodine-deficiency syndrome	0.717	0.283	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.717	0.283	0.000
E12 Malnutrition-related diabetes mellitus	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
E05.5 Thyroid crisis or storm	0.717	0.283	0.000
E05.4 Thyrotoxicosis factitia	0.717	0.283	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.717	0.283	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.717	0.283	0.000
E03.5 Myxoedema coma	0.717	0.283	0.000
E03.4 Atrophy of thyroid (acquired)	0.717	0.283	0.000
E03.3 Postinfectious hypothyroidism	0.717	0.283	0.000
E03.1 Congenital hypothyroidism without goitre	0.717	0.283	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283	0.000
E15 Nondiabetic hypoglycaemic coma	0.717	0.283	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.717	0.283	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.717	0.283	0.000
E16.4 Abnormal secretion of gastrin	0.717	0.283	0.000
E16.3 Increased secretion of glucagon	0.717	0.283	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283	0.000
D64.4 Congenital dyserythropoietic anaemia	0.717	0.283	0.000
D64.3 Other sideroblastic anaemias	0.717	0.283	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.717	0.283	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.717	0.283	0.000
D64.0 Hereditary sideroblastic anaemia	0.717	0.283	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.717	0.283	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.716	0.284	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.714	0.285	0.000
E20 Hypoparathyroidism	0.714	0.286	0.000
H34.1 Central retinal artery occlusion	0.714	0.286	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.286	0.714
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.286	0.714
K44.1 Diaphragmatic hernia with gangrene	0.001	0.287	0.713
M72.2 Plantar fascial fibromatosis	0.713	0.287	0.000
D04.1 Skin of eyelid, including canthus	0.713	0.287	0.000
K90.3 Pancreatic steatorrhoea	0.712	0.287	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.712	0.287	0.000
K90.1 Tropical sprue	0.712	0.287	0.000
N32.1 Vesicointestinal fistula	0.000	0.288	0.712
M62.6 Muscle strain	0.712	0.288	0.000
M23 Internal derangement of knee	0.712	0.288	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.712	0.288	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.711	0.289	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.711	0.289	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.711	0.289	0.000
M35.8 Other specified systemic involvement of connective tissue	0.711	0.289	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.711	0.289	0.000
M35.5 Multifocal fibrosclerosis	0.711	0.289	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.711	0.289	0.000
E14.7 With multiple complications	0.711	0.289	0.000
E14.5 With peripheral circulatory complications	0.711	0.289	0.000
E14.0 With coma	0.711	0.289	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.710	0.290	0.000
M08 Juvenile arthritis	0.710	0.290	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.000	0.290	0.710
T00-T07 Injuries involving multiple body regions	0.710	0.290	0.000
S91 Open wound of ankle and foot	0.709	0.291	0.000
H27 Other disorders of lens	0.709	0.291	0.000
E11.7 With multiple complications	0.708	0.292	0.000
M22.3 Other derangements of patella	0.708	0.292	0.000
I77.6 Arteritis, unspecified	0.708	0.292	0.000
E14.1 With ketoacidosis	0.706	0.294	0.000
E27.2 Addisonian crisis	0.705	0.295	0.000
H26.9 Cataract, unspecified	0.705	0.295	0.000
C95 Leukaemia of unspecified cell type	0.704	0.296	0.000
N42.8 Other specified disorders of prostate	0.000	0.296	0.704
H10-H13 Disorders of conjunctiva	0.703	0.297	0.000
M31.9 Necrotising vasculopathy, unspecified	0.699	0.300	0.000
M31.8 Other specified necrotising vasculopathies	0.699	0.300	0.000
M31.7 Microscopic polyangiitis	0.699	0.300	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.699	0.300	0.000
M31.2 Lethal midline granuloma	0.699	0.300	0.000
M31.1 Thrombotic microangiopathy	0.699	0.300	0.000
M31.0 Hypersensitivity angiitis	0.699	0.300	0.000
E03.8 Other specified hypothyroidism	0.699	0.301	0.000
H34.9 Retinal vascular occlusion, unspecified	0.699	0.301	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.699	0.301	0.000
E32 Diseases of thymus	0.699	0.301	0.000
E31 Polyglandular dysfunction	0.699	0.301	0.000
E30 Disorders of puberty, not elsewhere classified	0.699	0.301	0.000
E25 Adrenogenital disorders	0.699	0.301	0.000
K72.9 Hepatic failure, unspecified	0.699	0.301	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.698	0.302	0.000
M80 Osteoporosis with pathological fracture	0.697	0.303	0.000
E07 Other disorders of thyroid	0.697	0.303	0.000
S92.4 Fracture of great toe	0.696	0.304	0.000
X23 Contact with hornets, wasps and bees	0.695	0.305	0.000
N30.3 Trigonitis	0.000	0.305	0.695
N36.9 Urethral disorder, unspecified	0.000	0.305	0.695
L23 Allergic contact dermatitis	0.694	0.306	0.000
E27.5 Adrenomedullary hyperfunction	0.694	0.306	0.000
E27.0 Other adrenocortical overactivity	0.694	0.306	0.000
M35.7 Hypermobility syndrome	0.693	0.307	0.000
D83 Common variable immunodeficiency	0.693	0.307	0.000
H34.0 Transient retinal artery occlusion	0.693	0.307	0.000
L28 Lichen simplex chronicus and prurigo	0.693	0.307	0.000
D80 Immunodeficiency with predominantly antibody defects	0.692	0.307	0.000
N37 Urethral disorders in diseases classified elsewhere	0.000	0.308	0.692
N33 Bladder disorders in diseases classified elsewhere	0.000	0.308	0.692
T33-T35 Frostbite	0.692	0.308	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.692	0.308	0.000
Y00-Y09 Assault	0.692	0.308	0.000
C81.0 Lymphocytic predominance	0.692	0.308	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.688	0.309	0.004
H36.8 Other retinal disorders in diseases classified elsewhere	0.691	0.309	0.000
M60 Myositis	0.691	0.309	0.000
C43.8 Overlapping malignant melanoma of skin	0.690	0.310	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.690	0.310	0.000
C43.0 Malignant melanoma of lip	0.690	0.310	0.000
M76 Enthesopathies of lower limb, excluding foot	0.690	0.310	0.000
T16 Foreign body in ear	0.690	0.310	0.000
E23.2 Diabetes insipidus	0.689	0.310	0.000
N39.2 Orthostatic proteinuria, unspecified	0.000	0.311	0.689
N32.4 Rupture of bladder, nontraumatic	0.000	0.311	0.689
W45 Foreign body or object entering through skin	0.689	0.311	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.688	0.311	0.000
D51 Vitamin B12 deficiency anaemia	0.688	0.312	0.000
H43.0 Vitreous prolapse	0.688	0.312	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.688	0.312	0.000
M15 Polyarthrosis	0.688	0.312	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.688	0.312	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.687	0.313	0.000
K36 Other appendicitis	0.685	0.313	0.001
S48 Traumatic amputation of shoulder and upper arm	0.686	0.314	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.686	0.314	0.000
S44 Injury of nerves at shoulder and upper arm level	0.686	0.314	0.000
S47 Crushing injury of shoulder and upper arm	0.686	0.314	0.000
I62 Other nontraumatic intracranial haemorrhage	0.686	0.314	0.000
N39.3 Stress incontinence	0.000	0.315	0.685
M67 Other disorders of synovium and tendon	0.685	0.315	0.000
N41 Inflammatory diseases of prostate	0.000	0.315	0.685
N32.2 Vesical fistula, not elsewhere classified	0.000	0.315	0.684
H16 Keratitis	0.684	0.316	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.683	0.317	0.000
E11.0 With coma	0.682	0.318	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.681	0.318	0.000
D82 Immunodeficiency associated with other major defects	0.681	0.319	0.000
D81 Combined immunodeficiencies	0.681	0.319	0.000
H35.0 Background retinopathy and retinal vascular changes	0.680	0.319	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.680	0.320	0.000
H43.8 Other disorders of vitreous body	0.680	0.320	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.680	0.320	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.680	0.320	0.000
C00 Malignant neoplasm of lip	0.680	0.320	0.000
E61 Deficiency of other nutrient elements	0.680	0.320	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.680	0.320	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.680	0.320	0.000
S20.2 Contusion of thorax	0.680	0.320	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.679	0.321	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.679	0.321	0.000
M34.0 Progressive systemic sclerosis	0.679	0.321	0.000
S42 Fracture of shoulder and upper arm	0.679	0.321	0.000
H54 Blindness and low vision	0.678	0.322	0.000
S98 Traumatic amputation of ankle and foot	0.678	0.322	0.000
S97 Crushing injury of ankle and foot	0.678	0.322	0.000
S95 Injury of blood vessels at ankle and foot level	0.678	0.322	0.000
S94 Injury of nerves at ankle and foot level	0.678	0.322	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.678	0.322	0.000
D50.1 Sideropenic dysphagia	0.677	0.323	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.677	0.323	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.677	0.323	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.676	0.324	0.000
M24.7 Protrusio acetabuli	0.676	0.324	0.000
N30.0 Acute cystitis	0.000	0.324	0.676
I73.1 Thromboangiitis obliterans [Buerger]	0.675	0.325	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.675	0.325	0.000
C02.2 Ventral surface of tongue	0.675	0.325	0.000
T20 Burn and corrosion of head and neck	0.674	0.326	0.000
N46 Male infertility	0.000	0.326	0.674
N99-N99 Other disorders of the genitourinary system	0.000	0.326	0.674
E05.8 Other thyrotoxicosis	0.674	0.326	0.000
M13 Other arthritis	0.673	0.327	0.000
S43.1 Dislocation of acromioclavicular joint	0.673	0.327	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.672	0.328	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.672	0.328	0.000
Y10-Y34 Event of undetermined intent	0.672	0.328	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.671	0.329	0.000
N48.4 Impotence of organic origin	0.000	0.329	0.671
D09 Carcinoma in situ of other and unspecified sites	0.670	0.330	0.000
D06 Carcinoma in situ of cervix uteri	0.670	0.330	0.000
N36.1 Urethral diverticulum	0.000	0.331	0.669
W28 Contact with powered lawn mower	0.668	0.332	0.000
M07.6 Other enteropathic arthropathies	0.668	0.332	0.000
M07.5 Arthropathy in ulcerative colitis	0.668	0.332	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.668	0.332	0.000
M07.2 Psoriatic spondylitis	0.668	0.332	0.000
M07.1 Arthritis mutilans	0.668	0.332	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.668	0.332	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.668	0.332	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.668	0.332	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.668	0.332	0.000
K77 Liver disorders in diseases classified elsewhere	0.666	0.333	0.001
K71 Toxic liver disease	0.666	0.333	0.001
E53.8 Deficiency of other specified B group vitamins	0.667	0.333	0.000
Y35-Y36 Legal intervention and operations of war	0.666	0.334	0.000
X85-X99 Assault	0.666	0.334	0.000
X30-X39 Exposure to forces of nature	0.666	0.334	0.000
W65-W74 Accidental drowning and submersion	0.666	0.334	0.000
V98-V99 Other and unspecified transport accidents	0.666	0.334	0.000
V95-V97 Air and space transport accidents	0.666	0.334	0.000
V90-V94 Water transport accidents	0.666	0.334	0.000
V70-V79 Bus occupant injured in transport accident	0.666	0.334	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.666	0.334	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.666	0.334	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.666	0.334	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations