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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4468302
log Bayes Factor = 31.0559
Chromosome 10   position 60,164,572  (GRCh37) Explore rs4468302 on Ensembl!
Variant rs4468302 is part of Cluster X0189

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
N18 Chronic renal failure
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
Z92 Personal history of medical treatment
0.997 0.003 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
N18.9 Chronic renal failure, unspecified
0.993 0.007 0.000
Chapter IX Diseases of the circulatory system
0.993 0.007 0.000
N92 Excessive, frequent and irregular menstruation
0.993 0.007 0.000
M05-M14 Inflammatory polyarthropathies
0.991 0.009 0.000
Chapter VI Diseases of the nervous system
0.990 0.010 0.000
N17 Acute renal failure
0.989 0.011 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.989 0.011 0.000
I30-I52 Other forms of heart disease
0.987 0.013 0.000
N17.9 Acute renal failure, unspecified
0.982 0.018 0.000
Chapter X Diseases of the respiratory system
0.980 0.020 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.980 0.020 0.000
A00-A09 Intestinal infectious diseases
0.978 0.022 0.000
I50 Heart failure
0.976 0.024 0.000
D00-D09 In situ neoplasms
0.974 0.026 0.000
M50-M54 Other dorsopathies
0.971 0.029 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.969 0.031 0.000
E86 Volume depletion
0.968 0.032 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.967 0.033 0.000
E10-E14 Diabetes mellitus
0.966 0.034 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.964 0.036 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.963 0.037 0.000
Chapter VII Diseases of the eye and adnexa
0.962 0.038 0.000
D60-D64 Aplastic and other anaemias
0.961 0.039 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.960 0.040 0.000
I50.0 Congestive heart failure
0.958 0.042 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.956 0.044 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.954 0.046 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.952 0.048 0.000
A04 Other bacterial intestinal infections
0.952 0.048 0.000
N92.3 Ovulation bleeding
0.951 0.049 0.000
M06 Other rheumatoid arthritis
0.951 0.049 0.000
N10-N16 Renal tubulo-interstitial diseases
0.949 0.051 0.000
Chapter XX External causes of morbidity and mortality
0.947 0.053 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.945 0.055 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.944 0.056 0.000
M20-M25 Other joint disorders
0.944 0.056 0.000
D05 Carcinoma in situ of breast
0.943 0.057 0.000
N80 Endometriosis
0.939 0.061 0.000
E78.5 Hyperlipidaemia, unspecified
0.938 0.062 0.000
D64 Other anaemias
0.936 0.064 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.929 0.071 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.926 0.074 0.000
Z50 Care involving use of rehabilitation procedures
0.926 0.074 0.000
O60-O75 Complications of labour and delivery
0.925 0.075 0.000
B95-B98 Bacterial, viral and other infectious agents
0.925 0.075 0.000
J95-J99 Other diseases of the respiratory system
0.924 0.076 0.000
M13 Other arthritis
0.923 0.077 0.000
N92.6 Irregular menstruation, unspecified
0.922 0.078 0.000
M50 Cervical disk disorders
0.920 0.080 0.000
D64.9 Anaemia, unspecified
0.919 0.081 0.000
H30-H36 Disorders of choroid and retina
0.918 0.082 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.918 0.082 0.000
A04.8 Other specified bacterial intestinal infections
0.915 0.085 0.000
L40-L45 Papulosquamous disorders
0.913 0.087 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.913 0.087 0.000
C50-C50 Malignant neoplasm of breast
0.910 0.090 0.000
E10 Insulin-dependent diabetes mellitus
0.909 0.091 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.904 0.096 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.903 0.097 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.903 0.097 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.900 0.100 0.000
J30-J39 Other diseases of upper respiratory tract
0.898 0.102 0.000
I42 Cardiomyopathy
0.898 0.102 0.000
G40-G47 Episodic and paroxysmal disorders
0.897 0.103 0.000
C51-C58 Malignant neoplasms of female genital organs
0.897 0.103 0.000
N13 Obstructive and reflux uropathy
0.896 0.104 0.000
Z99.3 Dependence on wheelchair
0.893 0.107 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.892 0.108 0.000
D05.1 Intraductal carcinoma in situ
0.891 0.109 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.890 0.110 0.000
J98 Other respiratory disorders
0.888 0.112 0.000
M45-M49 Spondylopathies
0.886 0.114 0.000
M06.9 Rheumatoid arthritis, unspecified
0.885 0.115 0.000
N94.6 Dysmenorrhoea, unspecified
0.881 0.119 0.000
E11 Non-insulin-dependent diabetes mellitus
0.880 0.120 0.000
N76 Other inflammation of vagina and vulva
0.878 0.122 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.877 0.123 0.000
I05-I09 Chronic rheumatic heart diseases
0.875 0.125 0.000
J90-J94 Other diseases of pleura
0.874 0.126 0.000
M13.9 Arthritis, unspecified
0.874 0.126 0.000
Z96 Presence of other functional implants
0.873 0.127 0.000
N18.3 Chronic kidney disease, stage 3
0.873 0.127 0.000
G20-G26 Extrapyramidal and movement disorders
0.872 0.128 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.871 0.129 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.871 0.129 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.868 0.132 0.000
I50.1 Left ventricular failure
0.867 0.133 0.000
H33 Retinal detachments and breaks
0.867 0.133 0.000
M70-M79 Other soft tissue disorders
0.866 0.134 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.865 0.135 0.000
Z83 Family history of other specific disorders
0.865 0.135 0.000
L20-L30 Dermatitis and eczema
0.864 0.136 0.000
Z50.1 Other physical therapy
0.862 0.138 0.000
G90-G99 Other disorders of the nervous system
0.862 0.138 0.000
N87 Dysplasia of cervix uteri
0.862 0.138 0.000
N88 Other noninflammatory disorders of cervix uteri
0.861 0.139 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.859 0.141 0.000
O63 Long labour
0.858 0.142 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.858 0.142 0.000
M54 Dorsalgia
0.857 0.143 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.857 0.143 0.000
N18.5 Chronic kidney disease, stage 5
0.857 0.143 0.000
N25-N29 Other disorders of kidney and ureter
0.853 0.147 0.000
R87 Abnormal findings in specimens from female genital organs
0.851 0.149 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.850 0.150 0.000
N80.3 Endometriosis of pelvic peritoneum
0.849 0.151 0.000
E50-E64 Other nutritional deficiencies
0.847 0.153 0.000
C50 Malignant neoplasm of breast
0.847 0.153 0.000
L40 Psoriasis
0.845 0.155 0.000
R11 Nausea and vomiting
0.841 0.159 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.840 0.160 0.000
L08 Other local infections of skin and subcutaneous tissue
0.840 0.160 0.000
J09-J18 Influenza and pneumonia
0.838 0.161 0.000
Z51 Other medical care
0.834 0.166 0.000
J98.1 Pulmonary collapse
0.833 0.167 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.832 0.168 0.000
N18.2 Chronic kidney disease, stage 2
0.832 0.168 0.000
Z97 Presence of other devices
0.830 0.170 0.000
E10.9 Without complications
0.830 0.170 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.829 0.171 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.829 0.171 0.000
J90 Pleural effusion, not elsewhere classified
0.827 0.173 0.000
J34 Other disorders of nose and nasal sinuses
0.826 0.174 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.825 0.175 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.824 0.176 0.000
R87.6 Abnormal cytological findings
0.822 0.178 0.000
M31 Other necrotising vasculopathies
0.821 0.179 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.820 0.180 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.820 0.180 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.819 0.181 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.817 0.183 0.000
C64-C68 Malignant neoplasms of urinary tract
0.815 0.185 0.000
N85.0 Endometrial glandular hyperplasia
0.814 0.186 0.000
S00-S09 Injuries to the head
0.813 0.187 0.000
O63.1 Prolonged second stage (of labour)
0.811 0.189 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.810 0.190 0.000
C15-C26 Malignant neoplasms of digestive organs
0.810 0.190 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.809 0.191 0.000
S60-S69 Injuries to the wrist and hand
0.808 0.192 0.000
J60-J70 Lung diseases due to external agents
0.806 0.194 0.000
N86 Erosion and ectropion of cervix uteri
0.805 0.195 0.000
S70-S79 Injuries to the hip and thigh
0.804 0.196 0.000
N00-N08 Glomerular diseases
0.803 0.197 0.000
I73 Other peripheral vascular diseases
0.802 0.198 0.000
Z96.0 Presence of urogenital implants
0.802 0.198 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.800 0.200 0.000
D61 Other aplastic anaemias
0.800 0.200 0.000
N92.5 Other specified irregular menstruation
0.799 0.201 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.799 0.201 0.000
I35 Nonrheumatic aortic valve disorders
0.796 0.204 0.000
H33.2 Serous retinal detachment
0.795 0.205 0.000
E87.5 Hyperkalaemia
0.795 0.205 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.794 0.206 0.000
M05 Seropositive rheumatoid arthritis
0.794 0.206 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.794 0.206 0.000
E83 Disorders of mineral metabolism
0.793 0.207 0.000
E78.0 Pure hypercholesterolaemia
0.793 0.207 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.793 0.207 0.000
H43-H45 Disorders of vitreous body and globe
0.793 0.207 0.000
N85.2 Hypertrophy of uterus
0.793 0.207 0.000
Z92.8 Personal history of other medical treatment
0.792 0.208 0.000
M25 Other joint disorders, not elsewhere classified
0.792 0.208 0.000
M50.0 Cervical disk disorder with myelopathy
0.791 0.209 0.000
N80.0 Endometriosis of uterus
0.790 0.210 0.000
Z99.2 Dependence on renal dialysis
0.788 0.212 0.000
M50.1 Cervical disk disorder with radiculopathy
0.788 0.212 0.000
Z93 Artificial opening status
0.787 0.213 0.000
Chapter XXII Codes for special purposes
0.787 0.213 0.000
N99-N99 Other disorders of the genitourinary system
0.785 0.215 0.000
M06.4 Inflammatory polyarthropathy
0.784 0.216 0.000
G20 Parkinson's disease
0.783 0.217 0.000
Z51.5 Palliative care
0.783 0.217 0.000
C56 Malignant neoplasm of ovary
0.783 0.217 0.000
E20-E35 Disorders of other endocrine glands
0.782 0.218 0.000
L30 Other dermatitis
0.782 0.218 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.781 0.219 0.000
R30-R39 Symptoms and signs involving the urinary system
0.780 0.220 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.778 0.222 0.000
I08 Multiple valve diseases
0.778 0.222 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.778 0.222 0.000
M07 Psoriatic and enteropathic arthropathies
0.778 0.222 0.000
J98.8 Other specified respiratory disorders
0.777 0.223 0.000
Z85 Personal history of malignant neoplasm
0.777 0.223 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.776 0.224 0.000
T66-T78 Other and unspecified effects of external causes
0.775 0.225 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.775 0.225 0.000
I47 Paroxysmal tachycardia
0.775 0.225 0.000
N60-N64 Disorders of breast
0.774 0.226 0.000
I44 Atrioventricular and left bundle-branch block
0.773 0.227 0.000
Z99.1 Dependence on respirator
0.773 0.227 0.000
I42.0 Dilated cardiomyopathy
0.773 0.227 0.000
N83.2 Other and unspecified ovarian cysts
0.773 0.227 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.771 0.229 0.000
D06 Carcinoma in situ of cervix uteri
0.771 0.229 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.771 0.229 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.769 0.231 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.768 0.232 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.768 0.232 0.000
M86-M90 Other osteopathies
0.767 0.233 0.000
M23 Internal derangement of knee
0.766 0.234 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.766 0.234 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.765 0.235 0.000
M40-M43 Deforming dorsopathies
0.765 0.235 0.000
E11.2 With renal complications
0.765 0.235 0.000
M80-M85 Disorders of bone density and structure
0.764 0.236 0.000
N84 Polyp of female genital tract
0.764 0.236 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.763 0.237 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.763 0.237 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.763 0.237 0.000
N87.1 Moderate cervical dysplasia
0.763 0.237 0.000
S20-S29 Injuries to the thorax
0.762 0.237 0.000
M47 Spondylosis
0.762 0.238 0.000
H10-H13 Disorders of conjunctiva
0.762 0.238 0.000
N71 Inflammatory disease of uterus, except cervix
0.761 0.239 0.000
L40.9 Psoriasis, unspecified
0.761 0.239 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.761 0.239 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.760 0.239 0.000
M06.0 Seronegative rheumatoid arthritis
0.760 0.240 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.759 0.241 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.759 0.241 0.000
A04.5 Campylobacter enteritis
0.759 0.241 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.758 0.242 0.000
Z40 Prophylactic surgery
0.758 0.242 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.757 0.243 0.000
N80.1 Endometriosis of ovary
0.756 0.244 0.000
H36 Retinal disorders in diseases classified elsewhere
0.756 0.244 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.755 0.245 0.000
R18 Ascites
0.755 0.245 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.755 0.245 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.753 0.247 0.000
G44 Other headache syndromes
0.753 0.247 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.753 0.247 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.753 0.247 0.000
V20-V29 Motorcycle rider injured in transport accident
0.753 0.247 0.000
M22 Disorders of patella
0.751 0.249 0.000
E11.4 With neurological complications
0.751 0.249 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.750 0.250 0.000
Z03.4 Observation for suspected myocardial infarction
0.750 0.250 0.000
I42.9 Cardiomyopathy, unspecified
0.750 0.250 0.000
N76.2 Acute vulvitis
0.749 0.251 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.749 0.251 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.748 0.251 0.000
H34 Retinal vascular occlusions
0.748 0.252 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.748 0.252 0.000
N89 Other noninflammatory disorders of vagina
0.748 0.252 0.000
M79.6 Pain in limb
0.746 0.254 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.746 0.254 0.000
W20-W49 Exposure to inanimate mechanical forces
0.745 0.255 0.000
N94.1 Dyspareunia
0.745 0.255 0.000
N73 Other female pelvic inflammatory diseases
0.745 0.255 0.000
N75 Diseases of Bartholin's gland
0.745 0.255 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.745 0.255 0.000
D50-D53 Nutritional anaemias
0.745 0.255 0.000
I45 Other conduction disorders
0.744 0.256 0.000
Z99.8 Dependence on other enabling machines and devices
0.744 0.256 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.744 0.256 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.744 0.256 0.000
Z13 Special screening examination for other diseases and disorders
0.743 0.257 0.000
D46 Myelodysplastic syndromes
0.742 0.258 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.742 0.258 0.000
O62 Abnormalities of forces of labour
0.741 0.258 0.000
N70 Salpingitis and oophoritis
0.741 0.259 0.000
I51 Complications and ill-defined descriptions of heart disease
0.741 0.259 0.000
M50.2 Other cervical disk displacement
0.741 0.259 0.000
Chapter VIII Diseases of the ear and mastoid process
0.740 0.260 0.000
Z83.3 Family history of diabetes mellitus
0.740 0.260 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.739 0.261 0.000
B15-B19 Viral hepatitis
0.738 0.262 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.737 0.263 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.736 0.264 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.736 0.264 0.000
S06 Intracranial injury
0.736 0.264 0.000
J30 Vasomotor and allergic rhinitis
0.735 0.265 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.735 0.265 0.000
Z52 Donors of organs and tissues
0.734 0.266 0.000
H40-H42 Glaucoma
0.734 0.266 0.000
M31.6 Other giant cell arteritis
0.733 0.267 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.733 0.267 0.000
L90 Atrophic disorders of skin
0.733 0.267 0.000
E10.4 With neurological complications
0.733 0.267 0.000
Z04 Examination and observation for other reasons
0.733 0.267 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.732 0.267 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.732 0.268 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.732 0.268 0.000
I73.0 Raynaud's syndrome
0.732 0.268 0.000
C53 Malignant neoplasm of cervix uteri
0.731 0.269 0.000
S10-S19 Injuries to the neck
0.731 0.269 0.000
J18 Pneumonia, organism unspecified
0.731 0.269 0.000
E10.3 With ophthalmic complications
0.731 0.269 0.000
G47 Sleep disorders
0.730 0.270 0.000
G35 Multiple sclerosis
0.729 0.271 0.000
L89 Decubitus ulcer
0.728 0.272 0.000
Z41 Procedures for purposes other than remedying health state
0.728 0.272 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.728 0.272 0.000
Z83.7 Family history of diseases of the digestive system
0.728 0.272 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.728 0.272 0.000
N76.4 Abscess of vulva
0.727 0.273 0.000
E87.2 Acidosis
0.727 0.273 0.000
L50-L54 Urticaria and erythema
0.727 0.273 0.000
M35 Other systemic involvement of connective tissue
0.727 0.273 0.000
C34 Malignant neoplasm of bronchus and lung
0.727 0.273 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.727 0.273 0.000
H33.0 Retinal detachment with retinal break
0.727 0.273 0.000
I77 Other disorders of arteries and arterioles
0.726 0.274 0.000
E53 Deficiency of other B group vitamins
0.726 0.274 0.000
Z50.0 Cardiac rehabilitation
0.726 0.274 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.726 0.274 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.725 0.275 0.000
Z51.3 Blood transfusion without reported diagnosis
0.725 0.275 0.000
N18.4 Chronic kidney disease, stage 4
0.724 0.276 0.000
C50.9 Breast, unspecified
0.724 0.276 0.000
Z96.1 Presence of intraocular lens
0.722 0.278 0.000
L30.9 Dermatitis, unspecified
0.722 0.278 0.000
Z80 Family history of malignant neoplasm
0.720 0.280 0.000
S90-S99 Injuries to the ankle and foot
0.719 0.281 0.000
O36 Maternal care for other known or suspected foetal problems
0.719 0.281 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.719 0.281 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.719 0.281 0.000
Z90.5 Acquired absence of kidney
0.719 0.281 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.718 0.282 0.000
E83.1 Disorders of iron metabolism
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N82 Fistulae involving female genital tract
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
N18.8 Other chronic renal failure
0.716 0.284 0.000
N18.1 Chronic kidney disease, stage 1
0.716 0.284 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.716 0.284 0.000
I46 Cardiac arrest
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
L05 Pilonidal cyst
0.716 0.284 0.000
E85 Amyloidosis
0.715 0.284 0.000
E84 Cystic fibrosis
0.715 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.284 0.000
E73 Lactose intolerance
0.715 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.284 0.000
M11 Other crystal arthropathies
0.715 0.285 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.715 0.285 0.000
Z92.9 Personal history of medical treatment, unspecified
0.715 0.285 0.000
Z92.5 Personal history of rehabilitation measures
0.715 0.285 0.000
Z92.0 Personal history of contraception
0.715 0.285 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.715 0.285 0.000
L10-L14 Bullous disorders
0.714 0.285 0.000
J39 Other diseases of upper respiratory tract
0.714 0.286 0.000
N76.8 Other specified inflammation of vagina and vulva
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.713 0.287 0.000
R31 Unspecified haematuria
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.712 0.288 0.000
N92.4 Excessive bleeding in the premenopausal period
0.712 0.288 0.000
N92.2 Excessive menstruation at puberty
0.712 0.288 0.000
N93 Other abnormal uterine and vaginal bleeding
0.711 0.289 0.000
M14 Arthropathies in other diseases classified elsewhere
0.711 0.289 0.000
M12 Other specific arthropathies
0.711 0.289 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.711 0.289 0.000
M08 Juvenile arthritis
0.711 0.289 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.710 0.290 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.710 0.290 0.000
M48 Other spondylopathies
0.710 0.290 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
C50.4 Upper-outer quadrant of breast
0.710 0.290 0.000
N17.8 Other acute renal failure
0.709 0.291 0.000
N17.2 Acute renal failure with medullary necrosis
0.709 0.291 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.709 0.291 0.000
N17.0 Acute renal failure with tubular necrosis
0.709 0.291 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.709 0.291 0.000
G40 Epilepsy
0.709 0.291 0.000
J37 Chronic laryngitis and laryngotracheitis
0.708 0.292 0.000
Z48 Other surgical follow-up care
0.708 0.292 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.708 0.292 0.000
I52 Other heart disorders in diseases classified elsewhere
0.708 0.292 0.000
I48 Atrial fibrillation and flutter
0.708 0.292 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.708 0.292 0.000
I41 Myocarditis in diseases classified elsewhere
0.708 0.292 0.000
I40 Acute myocarditis
0.708 0.292 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.708 0.292 0.000
I37 Pulmonary valve disorders
0.708 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.708 0.292 0.000
I33 Acute and subacute endocarditis
0.708 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.708 0.292 0.000
I30 Acute pericarditis
0.708 0.292 0.000
M13.94 Arthritis, unspecified (Hand)
0.707 0.293 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.707 0.293 0.000
M24 Other specific joint derangements
0.707 0.293 0.000
M50.3 Other cervical disk degeneration
0.707 0.293 0.000
A30-A49 Other bacterial diseases
0.706 0.293 0.000
L40.5 Arthropathic psoriasis
0.706 0.294 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.706 0.294 0.000
M51 Other intervertebral disk disorders
0.705 0.295 0.000
Y40 Systemic antibiotics
0.704 0.296 0.000
I78 Diseases of capillaries
0.704 0.296 0.000
M72 Fibroblastic disorders
0.703 0.297 0.000
M21 Other acquired deformities of limbs
0.703 0.297 0.000
G41 Status epilepticus
0.703 0.297 0.000
Z45 Adjustment and management of implanted device
0.703 0.297 0.000
D55-D59 Haemolytic anaemias
0.702 0.298 0.000
B07 Viral warts
0.701 0.298 0.000
A07 Other protozoal intestinal diseases
0.701 0.299 0.000
A06 Amoebiasis
0.701 0.299 0.000
A05 Other bacterial foodborne intoxications
0.701 0.299 0.000
A03 Shigellosis
0.701 0.299 0.000
A02 Other Salmonella infections
0.701 0.299 0.000
A01 Typhoid and paratyphoid fevers
0.701 0.299 0.000
A00 Cholera
0.701 0.299 0.000
I71 Aortic aneurysm and dissection
0.700 0.300 0.000
G30-G32 Other degenerative diseases of the nervous system
0.699 0.300 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.700 0.300 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.699 0.301 0.000
D80-D89 Certain disorders involving the immune mechanism
0.699 0.301 0.000
E88 Other metabolic disorders
0.699 0.301 0.000
D09 Carcinoma in situ of other and unspecified sites
0.698 0.301 0.000
D04 Carcinoma in situ of skin
0.698 0.301 0.000
D03 Melanoma in situ
0.698 0.301 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.698 0.301 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.698 0.301 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.698 0.301 0.000
Z49 Care involving dialysis
0.698 0.302 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.698 0.302 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.698 0.302 0.000
J36 Peritonsillar abscess
0.698 0.302 0.000
R19.5 Other fecal abnormalities
0.698 0.302 0.000
S72 Fracture of femur
0.697 0.303 0.000
Z90.3 Acquired absence of part of stomach
0.697 0.303 0.000
M53 Other dorsopathies, not elsewhere classified
0.696 0.304 0.000
T79-T79 Certain early complications of trauma
0.696 0.304 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.695 0.305 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.695 0.305 0.000
E78.8 Other disorders of lipoprotein metabolism
0.695 0.305 0.000
E78.6 Lipoprotein deficiency
0.695 0.305 0.000
E78.4 Other hyperlipidaemia
0.695 0.305 0.000
E78.3 Hyperchylomicronaemia
0.695 0.305 0.000
E78.2 Mixed hyperlipidaemia
0.695 0.305 0.000
E78.1 Pure hyperglyceridaemia
0.695 0.305 0.000
M54.5 Low back pain
0.695 0.305 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.694 0.306 0.000
C50.5 Lower-outer quadrant of breast
0.694 0.306 0.000
O66 Other obstructed labour
0.694 0.306 0.000
B25-B34 Other viral diseases
0.694 0.306 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.693 0.307 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.693 0.307 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.693 0.307 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.693 0.307 0.000
Z82.2 Family history of deafness and hearing loss
0.693 0.307 0.000
Z82.1 Family history of blindness and visual loss
0.693 0.307 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.693 0.307 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.693 0.307 0.000
R07 Pain in throat and chest
0.693 0.307 0.000
E13 Other specified diabetes mellitus
0.693 0.307 0.000
E12 Malnutrition-related diabetes mellitus
0.693 0.307 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.691 0.309 0.000
Z99.4 Dependence on artificial heart
0.691 0.309 0.000
Z99.0 Dependence on aspirator
0.691 0.309 0.000
N94.5 Secondary dysmenorrhoea
0.690 0.310 0.000
N94.4 Primary dysmenorrhoea
0.690 0.310 0.000
N94.3 Premenstrual tension syndrome
0.690 0.310 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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