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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs45531831
log Bayes Factor = 17.5762
Chromosome 6   position 31,938,120  (GRCh37) Explore rs45531831 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
M06.9 Rheumatoid arthritis, unspecified
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.997 0.003 0.000
J45 Asthma
0.996 0.004 0.000
J45.9 Asthma, unspecified
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.992 0.008 0.000
E10.1 With ketoacidosis
0.985 0.015 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.973 0.027 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.972 0.028 0.000
J30-J39 Other diseases of upper respiratory tract
0.972 0.028 0.000
E10.4 With neurological complications
0.964 0.036 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.958 0.042 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.955 0.045 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.954 0.046 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.950 0.050 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.950 0.050 0.000
E14 Unspecified diabetes mellitus
0.950 0.050 0.000
O80-O84 Delivery
0.945 0.055 0.000
E11 Non-insulin-dependent diabetes mellitus
0.943 0.057 0.000
J09-J18 Influenza and pneumonia
0.943 0.057 0.000
Chapter VIII Diseases of the ear and mastoid process
0.936 0.064 0.000
M50-M54 Other dorsopathies
0.935 0.065 0.000
Chapter XX External causes of morbidity and mortality
0.931 0.069 0.000
O80 Single spontaneous delivery
0.930 0.070 0.000
Chapter VII Diseases of the eye and adnexa
0.930 0.070 0.000
Chapter I Certain infectious and parasitic diseases
0.930 0.070 0.000
H30-H36 Disorders of choroid and retina
0.919 0.081 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.918 0.082 0.000
O80.0 Spontaneous vertex delivery
0.918 0.082 0.000
H36.0 Diabetic retinopathy
0.918 0.082 0.000
H36 Retinal disorders in diseases classified elsewhere
0.917 0.083 0.000
M54 Dorsalgia
0.914 0.086 0.000
J34 Other disorders of nose and nasal sinuses
0.912 0.088 0.000
E10.5 With peripheral circulatory complications
0.910 0.090 0.000
E10.2 With renal complications
0.904 0.096 0.000
J33 Nasal polyp
0.903 0.097 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.896 0.104 0.000
L08 Other local infections of skin and subcutaneous tissue
0.886 0.114 0.000
B95-B98 Bacterial, viral and other infectious agents
0.885 0.115 0.000
E11.4 With neurological complications
0.882 0.118 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.882 0.118 0.000
T43.2 Other and unspecified antidepressants
0.878 0.122 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.875 0.125 0.000
M54.3 Sciatica
0.868 0.132 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.865 0.135 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.864 0.136 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.864 0.136 0.000
O60-O75 Complications of labour and delivery
0.860 0.140 0.000
E10.0 With coma
0.859 0.141 0.000
S50-S59 Injuries to the elbow and forearm
0.858 0.142 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.857 0.143 0.000
Chapter XXII Codes for special purposes
0.857 0.143 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.856 0.144 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.855 0.145 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.852 0.148 0.000
H53-H54 Visual disturbances and blindness
0.851 0.149 0.000
M86-M90 Other osteopathies
0.844 0.156 0.000
H65-H75 Diseases of middle ear and mastoid
0.844 0.156 0.000
E11.5 With peripheral circulatory complications
0.839 0.161 0.000
M65-M68 Disorders of synovium and tendon
0.838 0.162 0.000
M13 Other arthritis
0.838 0.162 0.000
E10.8 With unspecified complications
0.834 0.166 0.000
E14.9 Without complications
0.832 0.168 0.000
A30-A49 Other bacterial diseases
0.832 0.168 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.832 0.168 0.000
H54 Blindness and low vision
0.831 0.169 0.000
J44 Other chronic obstructive pulmonary disease
0.830 0.170 0.000
J42 Unspecified chronic bronchitis
0.827 0.173 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.823 0.177 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.821 0.179 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.818 0.182 0.000
J33.0 Polyp of nasal cavity
0.817 0.183 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.816 0.184 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.815 0.185 0.000
M54.4 Lumbago with sciatica
0.812 0.188 0.000
L05 Pilonidal cyst
0.808 0.192 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.808 0.192 0.000
H90-H95 Other disorders of ear
0.804 0.196 0.000
E14.3 With ophthalmic complications
0.803 0.197 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.802 0.198 0.000
J60-J70 Lung diseases due to external agents
0.801 0.199 0.000
M15-M19 Arthrosis
0.800 0.200 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.799 0.201 0.000
E14.6 With other specified complications
0.798 0.202 0.000
L03 Cellulitis
0.794 0.206 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.792 0.208 0.000
M54.36 Sciatica (Lumbar region)
0.789 0.211 0.000
M10 Gout
0.785 0.215 0.000
H60-H62 Diseases of external ear
0.782 0.218 0.000
H54.7 Unspecified visual loss
0.781 0.219 0.000
L20-L30 Dermatitis and eczema
0.781 0.219 0.000
M40-M43 Deforming dorsopathies
0.779 0.221 0.000
H55-H59 Other disorders of eye and adnexa
0.779 0.221 0.000
J33.9 Nasal polyp, unspecified
0.777 0.223 0.000
E20-E35 Disorders of other endocrine glands
0.776 0.224 0.000
T79-T79 Certain early complications of trauma
0.774 0.226 0.000
M14 Arthropathies in other diseases classified elsewhere
0.774 0.226 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.773 0.227 0.000
S10-S19 Injuries to the neck
0.772 0.228 0.000
S52 Fracture of forearm
0.770 0.230 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.768 0.232 0.000
J34.3 Hypertrophy of nasal turbinates
0.766 0.233 0.000
E11.0 With coma
0.766 0.234 0.000
M54.39 Sciatica (Site unspecified)
0.766 0.234 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.765 0.235 0.000
X60-X84 Intentional self-harm
0.763 0.237 0.000
J18 Pneumonia, organism unspecified
0.762 0.238 0.000
S40-S49 Injuries to the shoulder and upper arm
0.760 0.240 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.760 0.240 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.759 0.241 0.000
M60-M63 Disorders of muscles
0.757 0.243 0.000
H66 Suppurative and unspecified otitis media
0.757 0.243 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.755 0.244 0.000
J86 Pyothorax
0.755 0.245 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.753 0.247 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.750 0.250 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.750 0.250 0.000
H43-H45 Disorders of vitreous body and globe
0.749 0.251 0.000
M80-M85 Disorders of bone density and structure
0.749 0.251 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.749 0.251 0.000
M91-M94 Chondropathies
0.749 0.251 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.748 0.252 0.000
V10-V19 Pedal cyclist injured in transport accident
0.745 0.255 0.000
M18 Arthrosis of first carpometacarpal joint
0.743 0.257 0.000
E11.1 With ketoacidosis
0.742 0.258 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.741 0.259 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.741 0.259 0.000
T42.4 Benzodiazepines
0.739 0.261 0.000
M54.5 Low back pain
0.737 0.263 0.000
O72 Postpartum haemorrhage
0.737 0.263 0.000
A49 Bacterial infection of unspecified site
0.737 0.263 0.000
J10 Influenza due to identified influenza virus
0.733 0.267 0.000
H54.9 Unspecified visual impairment (binocular)
0.730 0.270 0.000
J34.2 Deviated nasal septum
0.728 0.272 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.727 0.273 0.000
J46 Status asthmaticus
0.727 0.273 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.727 0.273 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.725 0.275 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.724 0.276 0.000
J45.0 Predominantly allergic asthma
0.723 0.276 0.000
L03.0 Cellulitis of finger and toe
0.723 0.277 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.719 0.280 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.719 0.281 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.719 0.281 0.000
M07 Psoriatic and enteropathic arthropathies
0.718 0.282 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
J38.7 Other diseases of larynx
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.4 Inflammatory polyarthropathy
0.716 0.284 0.000
M06.3 Rheumatoid nodule
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.716 0.284 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.716 0.284 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.716 0.284 0.000
J41 Simple and mucopurulent chronic bronchitis
0.715 0.285 0.000
J45.8 Mixed asthma
0.714 0.286 0.000
J45.1 Nonallergic asthma
0.714 0.286 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
H54.0 Blindness, both eyes
0.711 0.289 0.000
M11 Other crystal arthropathies
0.710 0.290 0.000
H93 Other disorders of ear, not elsewhere classified
0.708 0.292 0.000
Chapter V Mental and behavioural disorders
0.708 0.292 0.000
T42.1 Iminostilbenes
0.708 0.292 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.707 0.293 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.707 0.293 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.706 0.294 0.000
J30 Vasomotor and allergic rhinitis
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
H65 Nonsuppurative otitis media
0.704 0.296 0.000
O80.9 Single spontaneous delivery, unspecified
0.704 0.296 0.000
J15.0 Pneumonia due to Klebsiella pneumoniae
0.704 0.296 0.000
T66-T78 Other and unspecified effects of external causes
0.703 0.296 0.000
J90-J94 Other diseases of pleura
0.703 0.297 0.000
M67 Other disorders of synovium and tendon
0.703 0.297 0.000
Y40 Systemic antibiotics
0.701 0.299 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.700 0.300 0.000
T43.9 Psychotropic drug, unspecified
0.698 0.302 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.698 0.302 0.000
T43.6 Psychostimulants with abuse potential
0.698 0.302 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.698 0.302 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.698 0.302 0.000
H60 Otitis externa
0.698 0.302 0.000
O85-O92 Complications predominantly related to the puerperium
0.697 0.303 0.000
J37 Chronic laryngitis and laryngotracheitis
0.697 0.303 0.000
Chapter VI Diseases of the nervous system
0.697 0.303 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.696 0.304 0.000
M89 Other disorders of bone
0.695 0.305 0.000
M53 Other dorsopathies, not elsewhere classified
0.693 0.307 0.000
T39.1 4-Aminophenol derivatives
0.693 0.307 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.693 0.307 0.000
J15.2 Pneumonia due to staphylococcus
0.692 0.308 0.000
A80-A89 Viral infections of the central nervous system
0.692 0.308 0.000
E13 Other specified diabetes mellitus
0.691 0.309 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.690 0.310 0.000
E40-E46 Malnutrition
0.690 0.310 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.690 0.310 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.689 0.311 0.000
E11.6 With other specified complications
0.688 0.312 0.000
M13.0 Polyarthritis, unspecified
0.688 0.312 0.000
S90-S99 Injuries to the ankle and foot
0.687 0.312 0.000
Y52 Agents primarily affecting the cardiovascular system
0.687 0.313 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.687 0.313 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.686 0.314 0.000
W50-W64 Exposure to animate mechanical forces
0.685 0.314 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.685 0.315 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.685 0.315 0.000
L10-L14 Bullous disorders
0.685 0.315 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.683 0.317 0.000
J86.9 Pyothorax without fistula
0.682 0.318 0.000
L04 Acute lymphadenitis
0.681 0.319 0.000
L01 Impetigo
0.681 0.319 0.000
L00 Staphylococcal scalded skin syndrome
0.681 0.319 0.000
E14.8 With unspecified complications
0.681 0.319 0.000
E14.7 With multiple complications
0.681 0.319 0.000
E14.5 With peripheral circulatory complications
0.681 0.319 0.000
E14.4 With neurological complications
0.681 0.319 0.000
E14.2 Withrenal complications
0.681 0.319 0.000
E14.1 With ketoacidosis
0.681 0.319 0.000
E14.0 With coma
0.681 0.319 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.681 0.319 0.000
J11 Influenza, virus not identified
0.680 0.319 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.680 0.320 0.000
H74 Other disorders of middle ear and mastoid
0.678 0.322 0.000
O84 Multiple delivery
0.677 0.323 0.000
O83 Other assisted single delivery
0.677 0.323 0.000
O81 Single delivery by forceps and vacuum extractor
0.677 0.323 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.677 0.323 0.000
E11.8 With unspecified complications
0.676 0.324 0.000
E11.7 With multiple complications
0.676 0.324 0.000
O62 Abnormalities of forces of labour
0.676 0.324 0.000
J17 Pneumonia in diseases classified elsewhere
0.676 0.324 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.676 0.324 0.000
J12 Viral pneumonia, not elsewhere classified
0.676 0.324 0.000
J14 Pneumonia due to Haemophilus influenzae
0.676 0.324 0.000
J09 Influenza due to certain identified influenza virus
0.676 0.324 0.000
H34 Retinal vascular occlusions
0.676 0.324 0.000
U80 Agent resistant to penicillin and related antibiotics
0.676 0.324 0.000
M06.0 Seronegative rheumatoid arthritis
0.675 0.324 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.675 0.325 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.673 0.327 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.671 0.329 0.000
J18.9 Pneumonia, unspecified
0.668 0.332 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.668 0.332 0.000
Y35-Y36 Legal intervention and operations of war
0.668 0.332 0.000
Y10-Y34 Event of undetermined intent
0.668 0.332 0.000
Y00-Y09 Assault
0.668 0.332 0.000
X85-X99 Assault
0.668 0.332 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.668 0.332 0.000
X50-X57 Overexertion, travel and privation
0.668 0.332 0.000
X30-X39 Exposure to forces of nature
0.668 0.332 0.000
X20-X29 Contact with venomous animals and plants
0.668 0.332 0.000
X10-X19 Contact with heat and hot substances
0.668 0.332 0.000
X00-X09 Exposure to smoke, fire and flames
0.668 0.332 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.668 0.332 0.000
W75-W84 Other accidental threats to breathing
0.668 0.332 0.000
W65-W74 Accidental drowning and submersion
0.668 0.332 0.000
V98-V99 Other and unspecified transport accidents
0.668 0.332 0.000
V95-V97 Air and space transport accidents
0.668 0.332 0.000
V90-V94 Water transport accidents
0.668 0.332 0.000
V80-V89 Other land transport accidents
0.668 0.332 0.000
V70-V79 Bus occupant injured in transport accident
0.668 0.332 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.668 0.332 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.668 0.332 0.000
V40-V49 Car occupant injured in transport accident
0.668 0.332 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.668 0.332 0.000
V01-V09 Pedestrian injured in transport accident
0.668 0.332 0.000
S20-S29 Injuries to the thorax
0.667 0.332 0.000
O80.8 Other single spontaneous delivery
0.667 0.333 0.000
O80.1 Spontaneous breech delivery
0.667 0.333 0.000
B99-B99 Other infectious diseases
0.667 0.333 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.667 0.333 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.667 0.333 0.000
B65-B83 Helminthiases
0.667 0.333 0.000
B50-B64 Protozoal diseases
0.667 0.333 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.667 0.333 0.000
A75-A79 Rickettsioses
0.667 0.333 0.000
A70-A74 Other diseases caused by chlamydiae
0.667 0.333 0.000
A65-A69 Other spirochaetal diseases
0.667 0.333 0.000
A20-A28 Certain zoonotic bacterial diseases
0.667 0.333 0.000
A15-A19 Tuberculosis
0.667 0.333 0.000
H66.9 Otitis media, unspecified
0.664 0.336 0.000
O36 Maternal care for other known or suspected foetal problems
0.664 0.336 0.000
M19 Other arthrosis
0.662 0.338 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.662 0.338 0.000
M54.9 Dorsalgia, unspecified
0.662 0.338 0.000
M05 Seropositive rheumatoid arthritis
0.660 0.340 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.660 0.340 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.660 0.340 0.000
J38.4 Oedema of larynx
0.660 0.340 0.000
Y44 Agents primarily affecting blood constituents
0.659 0.341 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.659 0.341 0.000
H31 Other disorders of choroid
0.659 0.341 0.000
H30 Chorioretinal inflammation
0.659 0.341 0.000
T50.8 Diagnostic agents
0.658 0.342 0.000
T50.7 Analeptics and opioid receptor antagonists
0.658 0.342 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.658 0.342 0.000
T50.5 Appetite depressants
0.658 0.342 0.000
T50.4 Drugs affecting uric acid metabolism
0.658 0.342 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.658 0.342 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.658 0.342 0.000
T50.1 Loop [high-ceiling] diuretics
0.658 0.342 0.000
T50.0 Mineralocorticoids and their antagonists
0.658 0.342 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.658 0.342 0.000
H43 Disorders of vitreous body
0.658 0.342 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.657 0.343 0.000
E11.3 With ophthalmic complications
0.657 0.343 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.656 0.344 0.000
L05.0 Pilonidal cyst with abscess
0.656 0.344 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.656 0.344 0.000
M54.8 Other dorsalgia
0.655 0.345 0.000
M54.6 Pain in thoracic spine
0.655 0.345 0.000
M54.0 Panniculitis affecting regions of neck and back
0.655 0.345 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.655 0.345 0.000
L05.9 Pilonidal cyst without abscess
0.655 0.345 0.000
M13.9 Arthritis, unspecified
0.655 0.345 0.000
L03.3 Cellulitis of trunk
0.655 0.345 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.654 0.346 0.000
Y57 Other and unspecified drugs and medicaments
0.654 0.346 0.000
M80 Osteoporosis with pathological fracture
0.653 0.347 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.652 0.348 0.000
A40 Streptococcal septicaemia
0.651 0.348 0.000
J47 Bronchiectasis
0.651 0.349 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.650 0.350 0.000
E50-E64 Other nutritional deficiencies
0.649 0.350 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.649 0.351 0.000
L29 Pruritus
0.649 0.351 0.000
S52.1 Fracture of upper end of radius
0.648 0.352 0.000
J33.1 Polypoid sinus degeneration
0.647 0.353 0.000
Q50-Q56 Congenital malformations of genital organs
0.647 0.353 0.000
J15.1 Pneumonia due to Pseudomonas
0.647 0.353 0.000
L50-L54 Urticaria and erythema
0.646 0.354 0.000
A49.8 Other bacterial infections of unspecified site
0.645 0.355 0.000
H90 Conductive and sensorineural hearing loss
0.645 0.355 0.000
Q60-Q64 Congenital malformations of the urinary system
0.644 0.356 0.000
H70 Mastoiditis and related conditions
0.644 0.356 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.644 0.356 0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.642 0.358 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.642 0.358 0.000
B15-B19 Viral hepatitis
0.642 0.358 0.000
H92 Otalgia and effusion of ear
0.641 0.359 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.641 0.359 0.000
M86 Osteomyelitis
0.640 0.359 0.000
H93.1 Tinnitus
0.639 0.361 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.638 0.362 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.638 0.362 0.000
S00-S09 Injuries to the head
0.637 0.363 0.000
E11.2 With renal complications
0.637 0.363 0.000
M88 Paget's disease of bone [osteitis deformans]
0.637 0.363 0.000
O47 False labour
0.635 0.365 0.000
L08.1 Erythrasma
0.635 0.365 0.000
L08.0 Pyoderma
0.635 0.365 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.634 0.365 0.000
O72.1 Other immediate postpartum haemorrhage
0.633 0.367 0.000
W20-W49 Exposure to inanimate mechanical forces
0.633 0.367 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.632 0.368 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.632 0.368 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.632 0.368 0.000
T42.3 Barbiturates
0.632 0.368 0.000
T42.2 Succinimides and oxazolidinediones
0.632 0.368 0.000
T42.0 Hydantoin derivatives
0.632 0.368 0.000
H57 Other disorders of eye and adnexa
0.631 0.369 0.000
M10.9 Gout, unspecified
0.631 0.369 0.000
J35 Chronic diseases of tonsils and adenoids
0.631 0.369 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.631 0.369 0.000
M54.2 Cervicalgia
0.631 0.369 0.000
M41 Scoliosis
0.627 0.373 0.000
Y59 Other and unspecified vaccines and biological substances
0.627 0.373 0.000
Y58 Bacterial vaccines
0.627 0.373 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.627 0.373 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.627 0.373 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.627 0.373 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.627 0.373 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.627 0.373 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.627 0.373 0.000
Y48 Anaesthetics and therapeutic gases
0.627 0.373 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.627 0.373 0.000
O66 Other obstructed labour
0.627 0.373 0.000
W00-W19 Falls
0.627 0.373 0.000
S70-S79 Injuries to the hip and thigh
0.626 0.374 0.000
L03.8 Cellulitis of other sites
0.626 0.374 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.625 0.375 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.624 0.376 0.000
S52.5 Fracture of lower end of radius
0.624 0.376 0.000
V20-V29 Motorcycle rider injured in transport accident
0.624 0.376 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.622 0.377 0.000
M54.37 Sciatica (Lumbosacral region)
0.622 0.377 0.000
M54.35 Sciatica (Thoracolumbar region)
0.622 0.377 0.000
M54.34 Sciatica-Thoracic
0.622 0.377 0.000
M54.33 Sciatica-Cervicothoracic
0.622 0.377 0.000
M54.32 Sciatica-Cervical
0.622 0.377 0.000
M54.31 Sciatica-Occipit-atl-axl
0.622 0.377 0.000
M54.30 Sciatica (Multiple sites in spine)
0.622 0.377 0.000
M90 Osteopathies in diseases classified elsewhere
0.622 0.377 0.000
X78 Intentional self-harm by sharp object
0.621 0.379 0.000
M54.1 Radiculopathy
0.621 0.379 0.000
Q80-Q89 Other congenital malformations
0.620 0.380 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.619 0.381 0.000
Q35-Q37 Cleft lip and cleft palate
0.619 0.381 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.619 0.381 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.619 0.381 0.000
Y43 Primarily systemic agents
0.619 0.381 0.000
Y42.5 Other oestrogens and progestogens
0.618 0.382 0.000
M65 Synovitis and tenosynovitis
0.618 0.382 0.000
M66 Spontaneous rupture of synovium and tendon
0.618 0.382 0.000
J38.1 Polyp of vocal cord and larynx
0.617 0.383 0.000
O74 Complications of anaesthesia during labour and delivery
0.617 0.383 0.000
O71 Other obstetric trauma
0.617 0.383 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.617 0.383 0.000
O61 Failed induction of labour
0.617 0.383 0.000
O60 Preterm delivery
0.617 0.383 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.616 0.384 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.616 0.384 0.000
S59 Other and unspecified injuries of forearm
0.615 0.385 0.000
S58 Traumatic amputation of forearm
0.615 0.385 0.000
S57 Crushing injury of forearm
0.615 0.385 0.000
S56 Injury of muscle and tendon at forearm level
0.615 0.385 0.000
S55 Injury of blood vessels at forearm level
0.615 0.385 0.000
S54 Injury of nerves at forearm level
0.615 0.385 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.615 0.385 0.000
S50 Superficial injury of forearm
0.615 0.385 0.000
J85 Abscess of lung and mediastinum
0.614 0.385 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.614 0.386 0.000
J15.9 Bacterial pneumonia, unspecified
0.614 0.386 0.000
J15.8 Other bacterial pneumonia
0.614 0.386 0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria
0.614 0.386 0.000
J15.5 Pneumonia due to Escherichia coli
0.614 0.386 0.000
J15.4 Pneumonia due to other streptococci
0.614 0.386 0.000
J15.3 Pneumonia due to streptococcus, group B
0.614 0.386 0.000
M67.1 Other contracture of tendon (sheath)
0.613 0.387 0.000
H66.3 Other chronic suppurative otitis media
0.613 0.387 0.000
S12 Fracture of neck
0.613 0.387 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.612 0.388 0.000
M14.6 Neuropathic arthropathy
0.612 0.388 0.000
J39 Other diseases of upper respiratory tract
0.612 0.388 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.612 0.388 0.000
Q00-Q07 Congenital malformations of the nervous system
0.612 0.388 0.000
S31 Open wound of abdomen, lower back and pelvis
0.611 0.389 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.610 0.390 0.000
M54.59 Low back pain (Site unspecified)
0.610 0.390 0.000
J95-J99 Other diseases of the respiratory system
0.609 0.391 0.000
S52.8 Fracture of other parts of forearm
0.608 0.392 0.000
E23 Hypofunction and other disorders of pituitary gland
0.608 0.392 0.000
L28 Lichen simplex chronicus and prurigo
0.607 0.393 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.607 0.393 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.607 0.393 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.606 0.394 0.000
J94 Other pleural conditions
0.606 0.394 0.000
A41 Other septicaemia
0.606 0.394 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.605 0.395 0.000
H68 Eustachian salpingitis and obstruction
0.605 0.395 0.000
H67 Otitis media in diseases classified elsewhere
0.605 0.395 0.000
J00-J06 Acute upper respiratory infections
0.605 0.395 0.000
H60.1 Cellulitis of external ear
0.604 0.396 0.000
J33.8 Other polyp of sinus
0.603 0.396 0.000
S40 Superficial injury of shoulder and upper arm
0.603 0.397 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.603 0.397 0.000
J18.0 Bronchopneumonia, unspecified
0.603 0.397 0.000
M40 Kyphosis and lordosis
0.603 0.397 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.602 0.398 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.601 0.399 0.000
M13.8 Other specified arthritis
0.601 0.399 0.000
M13.1 Monoarthritis, not elsewhere classified
0.601 0.399 0.000
T23 Burn and corrosion of wrist and hand
0.601 0.399 0.000
T91 Sequelae of injuries of neck and trunk
0.600 0.400 0.000
Y40.0 Penicillins
0.599 0.401 0.000
H69 Other disorders of Eustachian tube
0.599 0.401 0.000
J36 Peritonsillar abscess
0.598 0.402 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.598 0.402 0.000
O48 Prolonged pregnancy
0.598 0.402 0.000
A48 Other bacterial diseases, not elsewhere classified
0.596 0.403 0.000
A44 Bartonellosis
0.596 0.403 0.000
A43 Nocardiosis
0.596 0.403 0.000
A42 Actinomycosis
0.596 0.403 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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