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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs45599947
log Bayes Factor = 10.213
Chromosome 14   position 75,230,953  (GRCh37) Explore rs45599947 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
S00-S09 Injuries to the head
0.998 0.002 0.000
H40-H42 Glaucoma
0.997 0.003 0.000
H40 Glaucoma
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.991 0.009 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.991 0.009 0.000
Chapter VIII Diseases of the ear and mastoid process
0.989 0.011 0.000
H40.1 Primary open-angle glaucoma
0.982 0.018 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.977 0.023 0.000
S02 Fracture of skull and facial bones
0.974 0.026 0.000
T39.1 4-Aminophenol derivatives
0.970 0.030 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.967 0.033 0.000
H65-H75 Diseases of middle ear and mastoid
0.958 0.042 0.000
H55-H59 Other disorders of eye and adnexa
0.955 0.045 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.953 0.047 0.000
Chapter VI Diseases of the nervous system
0.952 0.048 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.952 0.048 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.951 0.049 0.000
M86-M90 Other osteopathies
0.942 0.058 0.000
G40-G47 Episodic and paroxysmal disorders
0.940 0.060 0.000
M20-M25 Other joint disorders
0.940 0.060 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.939 0.061 0.000
S00 Superficial injury of head
0.939 0.061 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.938 0.062 0.000
M05-M14 Inflammatory polyarthropathies
0.938 0.062 0.000
T43.2 Other and unspecified antidepressants
0.935 0.065 0.000
S50-S59 Injuries to the elbow and forearm
0.934 0.066 0.000
Y40 Systemic antibiotics
0.931 0.069 0.000
H40.9 Glaucoma, unspecified
0.925 0.075 0.000
Y44 Agents primarily affecting blood constituents
0.924 0.076 0.000
M80-M85 Disorders of bone density and structure
0.924 0.076 0.000
G43 Migraine
0.916 0.084 0.000
Chapter V Mental and behavioural disorders
0.916 0.084 0.000
H53-H54 Visual disturbances and blindness
0.916 0.084 0.000
Y45.0 Opioids and related analgesics
0.915 0.085 0.000
S80-S89 Injuries to the knee and lower leg
0.912 0.088 0.000
Chapter I Certain infectious and parasitic diseases
0.909 0.091 0.000
M07 Psoriatic and enteropathic arthropathies
0.902 0.097 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.902 0.098 0.000
H40.5 Glaucoma secondary to other eye disorders
0.902 0.098 0.000
M65-M68 Disorders of synovium and tendon
0.899 0.101 0.000
G43.9 Migraine, unspecified
0.898 0.102 0.000
S06 Intracranial injury
0.896 0.104 0.000
H54 Blindness and low vision
0.894 0.106 0.000
E10-E14 Diabetes mellitus
0.891 0.109 0.000
H73 Other disorders of tympanic membrane
0.881 0.119 0.000
S02.4 Fracture of malar and maxillary bones
0.880 0.120 0.000
S02.1 Fracture of base of skull
0.879 0.121 0.000
H40.8 Other glaucoma
0.879 0.121 0.000
M07.3 Other psoriatic arthropathies
0.878 0.122 0.000
Q60-Q64 Congenital malformations of the urinary system
0.876 0.124 0.000
Y44.2 Anticoagulants
0.876 0.124 0.000
E10 Insulin-dependent diabetes mellitus
0.875 0.125 0.000
T39.0 Salicylates
0.874 0.126 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.874 0.126 0.000
S40-S49 Injuries to the shoulder and upper arm
0.865 0.135 0.000
T17 Foreign body in respiratory tract
0.865 0.135 0.000
S00.8 Superficial injury of other parts of head
0.865 0.135 0.000
H57 Other disorders of eye and adnexa
0.863 0.137 0.000
Y40.9 Systemic antibiotic, unspecified
0.857 0.143 0.000
S80 Superficial injury of lower leg
0.854 0.146 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.852 0.148 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.852 0.148 0.000
T21 Burn and corrosion of trunk
0.848 0.152 0.000
H80-H83 Diseases of inner ear
0.842 0.158 0.000
G47 Sleep disorders
0.842 0.158 0.000
M89 Other disorders of bone
0.842 0.158 0.000
H54.0 Blindness, both eyes
0.842 0.158 0.000
S70-S79 Injuries to the hip and thigh
0.840 0.160 0.000
M81 Osteoporosis without pathological fracture
0.839 0.161 0.000
M67 Other disorders of synovium and tendon
0.833 0.167 0.000
M06 Other rheumatoid arthritis
0.833 0.167 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.833 0.167 0.000
G83 Other paralytic syndromes
0.831 0.169 0.000
F30-F39 Mood [affective] disorders
0.830 0.170 0.000
E20-E35 Disorders of other endocrine glands
0.830 0.170 0.000
M31 Other necrotising vasculopathies
0.829 0.171 0.000
S51 Open wound of forearm
0.828 0.172 0.000
M23 Internal derangement of knee
0.826 0.174 0.000
H73.8 Other specified disorders of tympanic membrane
0.826 0.174 0.000
S56 Injury of muscle and tendon at forearm level
0.824 0.176 0.000
E10.3 With ophthalmic complications
0.822 0.178 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.821 0.179 0.000
S80.9 Superficial injury of lower leg, unspecified
0.821 0.179 0.000
S01 Open wound of head
0.821 0.179 0.000
M25 Other joint disorders, not elsewhere classified
0.820 0.180 0.000
T17.2 Foreign body in pharynx
0.818 0.182 0.000
T93 Sequelae of injuries of lower limb
0.817 0.183 0.000
W00-W19 Falls
0.816 0.184 0.000
H55 Nystagmus and other irregular eye movements
0.814 0.186 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.813 0.187 0.000
Y40.0 Penicillins
0.812 0.188 0.000
S02.10 Fracture of base of skull (closed)
0.811 0.189 0.000
H72 Perforation of tympanic membrane
0.811 0.189 0.000
Q61 Cystic kidney disease
0.810 0.190 0.000
H65 Nonsuppurative otitis media
0.808 0.192 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.808 0.192 0.000
T91 Sequelae of injuries of neck and trunk
0.807 0.193 0.000
S20-S29 Injuries to the thorax
0.807 0.193 0.000
T23 Burn and corrosion of wrist and hand
0.806 0.194 0.000
H54.7 Unspecified visual loss
0.804 0.196 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.803 0.197 0.000
M24 Other specific joint derangements
0.802 0.198 0.000
M21 Other acquired deformities of limbs
0.802 0.198 0.000
M87 Osteonecrosis
0.801 0.198 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.800 0.200 0.000
H60-H62 Diseases of external ear
0.800 0.200 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.800 0.200 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.799 0.201 0.000
S00.4 Superficial injury of ear
0.796 0.204 0.000
W50-W64 Exposure to animate mechanical forces
0.794 0.206 0.000
M86 Osteomyelitis
0.793 0.207 0.000
E00-E07 Disorders of thyroid gland
0.792 0.208 0.000
S00.7 Multiple superficial injuries of head
0.791 0.209 0.000
H90-H95 Other disorders of ear
0.790 0.210 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.789 0.210 0.000
V80-V89 Other land transport accidents
0.788 0.212 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.786 0.214 0.000
F31 Bipolar affective disorder
0.783 0.217 0.000
G41 Status epilepticus
0.783 0.217 0.000
Y52 Agents primarily affecting the cardiovascular system
0.783 0.217 0.000
M40-M43 Deforming dorsopathies
0.782 0.218 0.000
S02.0 Fracture of vault of skull
0.782 0.218 0.000
G47.9 Sleep disorder, unspecified
0.781 0.219 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.780 0.220 0.000
M25.5 Pain in joint
0.779 0.221 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.778 0.222 0.000
M80 Osteoporosis with pathological fracture
0.778 0.222 0.000
S70 Superficial injury of hip and thigh
0.778 0.222 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.777 0.223 0.000
M67.8 Other specified disorders of synovium and tendon
0.777 0.223 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.775 0.225 0.000
E10.0 With coma
0.775 0.225 0.000
G82 Paraplegia and tetraplegia
0.774 0.226 0.000
G40 Epilepsy
0.774 0.226 0.000
T00-T07 Injuries involving multiple body regions
0.773 0.227 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.772 0.228 0.000
Q50-Q56 Congenital malformations of genital organs
0.769 0.231 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.769 0.231 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.766 0.234 0.000
S02.8 Fractures of other skull and facial bones
0.766 0.234 0.000
S81 Open wound of lower leg
0.766 0.234 0.000
V01-V09 Pedestrian injured in transport accident
0.765 0.235 0.000
Y45.5 4-Aminophenol derivatives
0.765 0.235 0.000
S00.1 Contusion of eyelid and periocular area
0.765 0.235 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.764 0.236 0.000
G30-G32 Other degenerative diseases of the nervous system
0.763 0.237 0.000
G83.4 Cauda equina syndrome
0.762 0.238 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.761 0.239 0.000
E28 Ovarian dysfunction
0.761 0.239 0.000
H40.2 Primary angle-closure glaucoma
0.761 0.239 0.000
M06.9 Rheumatoid arthritis, unspecified
0.760 0.240 0.000
B07 Viral warts
0.759 0.241 0.000
V10-V19 Pedal cyclist injured in transport accident
0.758 0.242 0.000
M89.8 Other specified disorders of bone
0.758 0.242 0.000
T19 Foreign body in genito-urinary tract
0.757 0.243 0.000
S02.6 Fracture of mandible
0.757 0.243 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.755 0.245 0.000
S05 Injury of eye and orbit
0.755 0.245 0.000
T40.2 Other opioids
0.752 0.247 0.000
M21.0 Valgus deformity, not elsewhere classified
0.751 0.249 0.000
H83 Other diseases of inner ear
0.751 0.249 0.000
F99-F99 Unspecified mental disorder
0.750 0.250 0.000
S51.9 Open wound of forearm, part unspecified
0.750 0.250 0.000
S06.3 Focal brain injury
0.750 0.250 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.748 0.252 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.748 0.252 0.000
M81.4 Drug-induced osteoporosis
0.747 0.253 0.000
E10.4 With neurological complications
0.746 0.254 0.000
Y48 Anaesthetics and therapeutic gases
0.745 0.255 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.745 0.255 0.000
M25.8 Other specified joint disorders
0.744 0.256 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.744 0.256 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.744 0.256 0.000
M25.51 Pain in joint (Shoulder region)
0.741 0.259 0.000
T90 Sequelae of injuries of head
0.740 0.260 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.740 0.260 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.740 0.260 0.000
H71 Cholesteatoma of middle ear
0.739 0.261 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.739 0.261 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.735 0.265 0.000
H74 Other disorders of middle ear and mastoid
0.735 0.265 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.734 0.266 0.000
T92 Sequelae of injuries of upper limb
0.733 0.266 0.000
Q61.3 Polycystic kidney, unspecified
0.733 0.267 0.000
Q80-Q89 Other congenital malformations
0.733 0.267 0.000
S40 Superficial injury of shoulder and upper arm
0.732 0.268 0.000
H57.8 Other specified disorders of eye and adnexa
0.732 0.268 0.000
M12 Other specific arthropathies
0.731 0.269 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.730 0.270 0.000
S10-S19 Injuries to the neck
0.728 0.272 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.728 0.272 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.727 0.272 0.000
M33 Dermatopolymyositis
0.727 0.273 0.000
A80-A89 Viral infections of the central nervous system
0.726 0.274 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.726 0.274 0.000
M23.3 Other meniscus derangements
0.726 0.274 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.725 0.275 0.000
G47.3 Sleep apnoea
0.724 0.276 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.724 0.276 0.000
S59 Other and unspecified injuries of forearm
0.724 0.276 0.000
S02.7 Multiple fractures involving skull and facial bones
0.724 0.276 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.724 0.276 0.000
T21.0 Burn of unspecified degree of trunk
0.724 0.276 0.000
H46 Optic neuritis
0.722 0.278 0.000
T91.3 Sequelae of injury of spinal cord
0.722 0.278 0.000
S06.2 Diffuse brain injury
0.720 0.280 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.720 0.280 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.720 0.280 0.000
E10.2 With renal complications
0.719 0.281 0.000
X50-X57 Overexertion, travel and privation
0.719 0.281 0.000
M66 Spontaneous rupture of synovium and tendon
0.718 0.282 0.000
Chapter XXII Codes for special purposes
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
A00-A09 Intestinal infectious diseases
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.283 0.000
T36 Poisoning by systemic antibiotics
0.716 0.283 0.000
S08 Traumatic amputation of part of head
0.716 0.284 0.000
S07 Crushing injury of head
0.716 0.284 0.000
S04 Injury of cranial nerves
0.716 0.284 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.716 0.284 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.716 0.284 0.000
H42 Glaucoma in diseases classified elsewhere
0.715 0.285 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.715 0.285 0.000
H40.6 Glaucoma secondary to drugs
0.714 0.286 0.000
H40.4 Glaucoma secondary to eye inflammation
0.714 0.286 0.000
H40.3 Glaucoma secondary to eye trauma
0.714 0.286 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.712 0.287 0.000
E28.2 Polycystic ovarian syndrome
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
H57.1 Ocular pain
0.712 0.288 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.711 0.289 0.000
T39.4 Antirheumatics, not elsewhere classified
0.711 0.289 0.000
T39.2 Pyrazolone derivatives
0.711 0.289 0.000
Y59 Other and unspecified vaccines and biological substances
0.711 0.289 0.000
Y58 Bacterial vaccines
0.711 0.289 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.711 0.289 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.711 0.289 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.710 0.290 0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level
0.709 0.291 0.000
S02.5 Fracture of tooth
0.708 0.291 0.000
T20 Burn and corrosion of head and neck
0.708 0.292 0.000
M84 Disorders of continuity of bone
0.708 0.292 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.708 0.292 0.000
E21.0 Primary hyperparathyroidism
0.708 0.292 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.708 0.292 0.000
G43.8 Other migraine
0.707 0.293 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.707 0.293 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
S29 Other and unspecified injuries of thorax
0.705 0.295 0.000
T21.2 Burn of second degree of trunk
0.704 0.296 0.000
M60-M63 Disorders of muscles
0.703 0.296 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.703 0.296 0.000
S01.3 Open wound of ear
0.702 0.298 0.000
M14 Arthropathies in other diseases classified elsewhere
0.702 0.298 0.000
Y45.2 Propionic acid derivatives
0.701 0.299 0.000
T43.9 Psychotropic drug, unspecified
0.700 0.300 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.700 0.300 0.000
T43.6 Psychostimulants with abuse potential
0.700 0.300 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.700 0.300 0.000
G80 Infantile cerebral palsy
0.700 0.300 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.700 0.300 0.000
S54 Injury of nerves at forearm level
0.699 0.301 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.698 0.302 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.698 0.302 0.000
G43.0 Migraine without aura [common migraine]
0.697 0.303 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.697 0.303 0.000
B35-B49 Mycoses
0.697 0.303 0.000
Y00-Y09 Assault
0.697 0.303 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.696 0.304 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.696 0.304 0.000
W13 Fall from, out of or through building or structure
0.695 0.305 0.000
H61 Other disorders of external ear
0.695 0.305 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.694 0.306 0.000
B91 Sequelae of poliomyelitis
0.694 0.306 0.000
Y57 Other and unspecified drugs and medicaments
0.694 0.306 0.000
T18 Foreign body in alimentary tract
0.694 0.306 0.000
Q63 Other congenital malformations of kidney
0.694 0.306 0.000
H70 Mastoiditis and related conditions
0.694 0.306 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.694 0.306 0.000
Q35-Q37 Cleft lip and cleft palate
0.694 0.306 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.694 0.306 0.000
T16 Foreign body in ear
0.691 0.309 0.000
S50 Superficial injury of forearm
0.691 0.309 0.000
W20-W49 Exposure to inanimate mechanical forces
0.690 0.309 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.690 0.310 0.000
M25.56 Pain in joint (Lower leg)
0.689 0.311 0.000
M88 Paget's disease of bone [osteitis deformans]
0.688 0.312 0.000
H54.9 Unspecified visual impairment (binocular)
0.688 0.312 0.000
M31.3 Wegener's granulomatosis
0.688 0.312 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.688 0.312 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.687 0.313 0.000
H68 Eustachian salpingitis and obstruction
0.687 0.313 0.000
H67 Otitis media in diseases classified elsewhere
0.687 0.313 0.000
M86.9 Osteomyelitis, unspecified
0.686 0.314 0.000
Y45.1 Salicylates
0.685 0.314 0.000
M89.87 Other specified disorders of bone (Ankle and foot)
0.686 0.314 0.000
S00.9 Superficial injury of head, part unspecified
0.685 0.314 0.000
M81.49 Drug-induced osteoporosis (Site unspecified)
0.684 0.316 0.000
T25 Burn and corrosion of ankle and foot
0.683 0.317 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.683 0.317 0.000
M00-M03 Infectious arthropathies
0.683 0.317 0.000
V40-V49 Car occupant injured in transport accident
0.683 0.317 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.682 0.318 0.000
Y45.4 Antirheumatics
0.682 0.318 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.682 0.318 0.000
Y45.8 Other analgesics and antipyretics
0.680 0.320 0.000
T93.1 Sequelae of fracture of femur
0.679 0.321 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.679 0.321 0.000
M87.2 Osteonecrosis due to previous trauma
0.678 0.322 0.000
S01.8 Open wound of other parts of head
0.677 0.323 0.000
M25.3 Other instability of joint
0.677 0.323 0.000
E25 Adrenogenital disorders
0.676 0.324 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.676 0.324 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.676 0.324 0.000
M22 Disorders of patella
0.676 0.324 0.000
S09 Other and unspecified injuries of head
0.675 0.325 0.000
F30 Manic episode
0.675 0.325 0.000
Q00-Q07 Congenital malformations of the nervous system
0.674 0.326 0.000
H30-H36 Disorders of choroid and retina
0.674 0.326 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.674 0.326 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.674 0.326 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.674 0.326 0.000
M32 Systemic lupus erythematosus
0.674 0.326 0.000
H65.4 Other chronic nonsuppurative otitis media
0.673 0.327 0.000
T15 Foreign body on external eye
0.673 0.327 0.000
S00.5 Superficial injury of lip and oral cavity
0.673 0.327 0.000
T95 Sequelae of burns, corrosions and frostbite
0.673 0.327 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.673 0.327 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.673 0.327 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.672 0.328 0.000
M08 Juvenile arthritis
0.672 0.328 0.000
S06.5 Traumatic subdural haemorrhage
0.672 0.328 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.671 0.329 0.000
B95-B98 Bacterial, viral and other infectious agents
0.671 0.329 0.000
M81.2 Osteoporosis of disuse
0.671 0.329 0.000
M25.59 Pain in joint (Site unspecified)
0.670 0.330 0.000
M31.6 Other giant cell arteritis
0.670 0.330 0.000
S58 Traumatic amputation of forearm
0.670 0.330 0.000
S57 Crushing injury of forearm
0.670 0.330 0.000
S55 Injury of blood vessels at forearm level
0.670 0.330 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.670 0.330 0.000
G47.4 Narcolepsy and cataplexy
0.670 0.330 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.668 0.332 0.000
E65-E68 Obesity and other hyperalimentation
0.668 0.332 0.000
Y40.7 Antifungal antibiotics, systemically used
0.667 0.333 0.000
Y40.6 Rifamycins
0.667 0.333 0.000
Y40.5 Aminoglycosides
0.667 0.333 0.000
Y40.4 Tetracyclines
0.667 0.333 0.000
Y40.2 Chloramphenicol group
0.667 0.333 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.667 0.333 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.667 0.333 0.000
T98 Sequelae of other and unspecified effects of external causes
0.666 0.334 0.000
F00 Dementia in Alzheimer's disease
0.666 0.334 0.000
G40.9 Epilepsy, unspecified
0.665 0.335 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.665 0.335 0.000
H80 Otosclerosis
0.665 0.335 0.000
T40.4 Other synthetic narcotics
0.664 0.335 0.000
V20-V29 Motorcycle rider injured in transport accident
0.664 0.336 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.664 0.336 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.664 0.336 0.000
E40-E46 Malnutrition
0.663 0.337 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.663 0.337 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.663 0.337 0.000
Y44.7 Plasma substitutes
0.663 0.337 0.000
Y44.6 Natural blood and blood products
0.663 0.337 0.000
Y44.5 Thrombolytic drugs
0.663 0.337 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.663 0.337 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.663 0.337 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.663 0.337 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.663 0.337 0.000
H83.0 Labyrinthitis
0.662 0.338 0.000
G44 Other headache syndromes
0.662 0.338 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.662 0.338 0.000
M83 Adult osteomalacia
0.662 0.338 0.000
A04 Other bacterial intestinal infections
0.662 0.338 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.661 0.339 0.000
S02.3 Fracture of orbital floor
0.660 0.340 0.000
X20-X29 Contact with venomous animals and plants
0.660 0.340 0.000
G83.1 Monoplegia of lower limb
0.659 0.341 0.000
Q76 Congenital malformations of spine and bony thorax
0.659 0.341 0.000
E50-E64 Other nutritional deficiencies
0.658 0.342 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.658 0.342 0.000
Y40.8 Other systemic antibiotics
0.657 0.343 0.000
S01.9 Open wound of head, part unspecified
0.657 0.343 0.000
G43.3 Complicated migraine
0.657 0.343 0.000
G43.2 Status migrainosus
0.657 0.343 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.657 0.343 0.000
F70-F79 Mental retardation
0.657 0.343 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.657 0.343 0.000
T40.6 Other and unspecified narcotics
0.656 0.344 0.000
F60-F69 Disorders of adult personality and behaviour
0.656 0.344 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.655 0.345 0.000
S88 Traumatic amputation of lower leg
0.654 0.346 0.000
S87 Crushing injury of lower leg
0.654 0.346 0.000
S85 Injury of blood vessels at lower leg level
0.654 0.346 0.000
S84 Injury of nerves at lower leg level
0.654 0.346 0.000
M34 Systemic sclerosis
0.653 0.346 0.000
Q61.2 Polycystic kidney, adult type
0.653 0.347 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.652 0.348 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.652 0.348 0.000
A75-A79 Rickettsioses
0.652 0.348 0.000
A70-A74 Other diseases caused by chlamydiae
0.652 0.348 0.000
A65-A69 Other spirochaetal diseases
0.652 0.348 0.000
A20-A28 Certain zoonotic bacterial diseases
0.652 0.348 0.000
A15-A19 Tuberculosis
0.652 0.348 0.000
S70.1 Contusion of thigh
0.652 0.348 0.000
B50-B64 Protozoal diseases
0.651 0.349 0.000
S01.2 Open wound of nose
0.651 0.349 0.000
M30 Polyarteritis nodosa and related conditions
0.650 0.350 0.000
H92 Otalgia and effusion of ear
0.650 0.350 0.000
T23.3 Burn of third degree of wrist and hand
0.650 0.350 0.000
Q18 Other congenital malformations of face and neck
0.649 0.351 0.000
T51 Toxic effect of alcohol
0.648 0.352 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.648 0.352 0.000
M24.1 Other articular cartilage disorders
0.647 0.353 0.000
M07.6 Other enteropathic arthropathies
0.647 0.353 0.000
M07.5 Arthropathy in ulcerative colitis
0.647 0.353 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.647 0.353 0.000
M07.2 Psoriatic spondylitis
0.647 0.353 0.000
M07.1 Arthritis mutilans
0.647 0.353 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.647 0.353 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.647 0.353 0.000
E13 Other specified diabetes mellitus
0.646 0.354 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.646 0.354 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.646 0.354 0.000
H69 Other disorders of Eustachian tube
0.645 0.354 0.000
S01.5 Open wound of lip and oral cavity
0.645 0.355 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.645 0.355 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.644 0.355 0.000
S02.00 Fracture of vault of skull (closed)
0.644 0.356 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.644 0.356 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.643 0.356 0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level
0.643 0.356 0.000
H65.0 Acute serous otitis media
0.643 0.357 0.000
W11 Fall on and from ladder
0.642 0.358 0.000
S06.9 Intracranial injury, unspecified
0.642 0.358 0.000
S06.7 Intracranial injury with prolonged coma
0.642 0.358 0.000
S06.1 Traumatic cerebral oedema
0.642 0.358 0.000
H54.6 Unqualified visual loss, one eye
0.641 0.359 0.000
H54.5 Low vision, one eye
0.641 0.359 0.000
H54.3 Unqualified visual loss, both eyes
0.641 0.359 0.000
H54.2 Low vision, both eyes
0.641 0.359 0.000
H54.1 Blindness, one eye, low vision, other eye
0.641 0.359 0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level
0.641 0.359 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.640 0.359 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.640 0.359 0.000
M06.3 Rheumatoid nodule
0.640 0.360 0.000
E12 Malnutrition-related diabetes mellitus
0.639 0.361 0.000
H65.2 Chronic serous otitis media
0.638 0.362 0.000
W10 Fall on and from stairs and steps
0.638 0.362 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.638 0.362 0.000
G41.0 Grand mal status epilepticus
0.637 0.363 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.635 0.365 0.000
Q24 Other congenital malformations of heart
0.635 0.365 0.000
M82 Osteoporosis in diseases classified elsewhere
0.634 0.366 0.000
M25.84 Other specified joint disorders (Hand)
0.634 0.366 0.000
G82.1 Spastic paraplegia
0.633 0.367 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.633 0.367 0.000
B94 Sequelae of other and unspecified infectious and parasitic diseases
0.632 0.367 0.000
W08 Fall involving other furniture
0.632 0.368 0.000
F99 Mental disorder, not otherwise specified
0.632 0.368 0.000
H73.9 Disorder of tympanic membrane, unspecified
0.632 0.368 0.000
H73.1 Chronic myringitis
0.632 0.368 0.000
H73.0 Acute myringitis
0.632 0.368 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.631 0.368 0.000
S29.9 Unspecified injury of thorax
0.631 0.369 0.000
S02.41 Fracture of malar and maxillary bones (open)
0.631 0.369 0.000
S06.8 Other intracranial injuries
0.631 0.369 0.000
G70-G73 Diseases of myoneural junction and muscle
0.630 0.370 0.000
S02.11 Fracture of base of skull (open)
0.630 0.370 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.630 0.370 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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