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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4746853
log Bayes Factor = 18.9277
Chromosome 10   position 64,181,219  (GRCh37) Explore rs4746853 on Ensembl!
Variant rs4746853 is part of Cluster X0044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.997 0.003 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.995 0.005 0.000
I30-I52 Other forms of heart disease
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
Chapter VII Diseases of the eye and adnexa
0.986 0.014 0.000
M20-M25 Other joint disorders
0.981 0.019 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.981 0.019 0.000
T81 Complications of procedures, not elsewhere classified
0.972 0.028 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.967 0.033 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.965 0.035 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.959 0.041 0.000
M80-M85 Disorders of bone density and structure
0.954 0.046 0.000
J09-J18 Influenza and pneumonia
0.953 0.047 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.949 0.051 0.000
Z50 Care involving use of rehabilitation procedures
0.941 0.059 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.939 0.061 0.000
M45-M49 Spondylopathies
0.939 0.061 0.000
Z51 Other medical care
0.938 0.062 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.938 0.062 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.937 0.063 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.927 0.073 0.000
Z93 Artificial opening status
0.924 0.076 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.923 0.077 0.000
J18 Pneumonia, organism unspecified
0.922 0.078 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.921 0.079 0.000
H01 Other inflammation of eyelid
0.921 0.079 0.000
J40-J47 Chronic lower respiratory diseases
0.916 0.084 0.000
E70-E90 Metabolic disorders
0.915 0.085 0.000
Z96 Presence of other functional implants
0.915 0.085 0.000
R50-R69 General symptoms and signs
0.914 0.086 0.000
Z53.0 Procedure not carried out because of contraindication
0.914 0.086 0.000
I50 Heart failure
0.914 0.086 0.000
Z47 Other orthopaedic follow-up care
0.913 0.087 0.000
G40-G47 Episodic and paroxysmal disorders
0.910 0.090 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.908 0.092 0.000
Z92 Personal history of medical treatment
0.905 0.095 0.000
R51 Headache
0.903 0.097 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.899 0.101 0.000
I34 Nonrheumatic mitral valve disorders
0.899 0.101 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.895 0.105 0.000
M31 Other necrotising vasculopathies
0.895 0.105 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.893 0.106 0.000
M05-M14 Inflammatory polyarthropathies
0.890 0.110 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.890 0.110 0.000
H01.0 Blepharitis
0.889 0.111 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.886 0.114 0.000
I42 Cardiomyopathy
0.884 0.116 0.000
Z50.0 Cardiac rehabilitation
0.884 0.116 0.000
H00 Hordeolum and chalazion
0.884 0.116 0.000
M47 Spondylosis
0.878 0.122 0.000
I20-I25 Ischaemic heart diseases
0.877 0.123 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.877 0.123 0.000
Chapter I Certain infectious and parasitic diseases
0.875 0.125 0.000
Z41 Procedures for purposes other than remedying health state
0.874 0.126 0.000
J45 Asthma
0.873 0.127 0.000
S00-S09 Injuries to the head
0.873 0.127 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.872 0.128 0.000
I44 Atrioventricular and left bundle-branch block
0.869 0.131 0.000
W00-W19 Falls
0.867 0.133 0.000
M25 Other joint disorders, not elsewhere classified
0.866 0.134 0.000
M81 Osteoporosis without pathological fracture
0.863 0.137 0.000
Chapter VIII Diseases of the ear and mastoid process
0.857 0.142 0.000
M70-M79 Other soft tissue disorders
0.856 0.144 0.000
G20-G26 Extrapyramidal and movement disorders
0.855 0.145 0.000
I51 Complications and ill-defined descriptions of heart disease
0.855 0.145 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.854 0.146 0.000
Y83.6 Removal of other organ (partial) (total)
0.852 0.148 0.000
G30-G32 Other degenerative diseases of the nervous system
0.852 0.148 0.000
J45.9 Asthma, unspecified
0.851 0.149 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.850 0.150 0.000
Z93.2 Ileostomy status
0.848 0.152 0.000
J18.9 Pneumonia, unspecified
0.848 0.152 0.000
M35 Other systemic involvement of connective tissue
0.847 0.153 0.000
R69 Unknown and unspecified causes of morbidity
0.846 0.154 0.000
S50-S59 Injuries to the elbow and forearm
0.842 0.158 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.839 0.160 0.000
I31 Other diseases of pericardium
0.839 0.161 0.000
M23 Internal derangement of knee
0.838 0.162 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.836 0.164 0.000
Z95.0 Presence of cardiac pacemaker
0.834 0.166 0.000
I95 Hypotension
0.832 0.167 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.830 0.170 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.828 0.172 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.826 0.174 0.000
H00.1 Chalazion
0.825 0.175 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.824 0.176 0.000
M13 Other arthritis
0.824 0.176 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.822 0.178 0.000
I25 Chronic ischaemic heart disease
0.821 0.179 0.000
M47.9 Spondylosis, unspecified
0.820 0.180 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.816 0.184 0.000
E83 Disorders of mineral metabolism
0.815 0.185 0.000
J18.1 Lobar pneumonia, unspecified
0.815 0.185 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.814 0.186 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.814 0.186 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.814 0.186 0.000
I50.0 Congestive heart failure
0.813 0.187 0.000
R40 Somnolence, stupor and coma
0.813 0.187 0.000
I33 Acute and subacute endocarditis
0.812 0.188 0.000
J00-J06 Acute upper respiratory infections
0.809 0.191 0.000
S40-S49 Injuries to the shoulder and upper arm
0.809 0.191 0.000
I05-I09 Chronic rheumatic heart diseases
0.809 0.191 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.808 0.192 0.000
Z51.1 Chemotherapy session for neoplasm
0.808 0.192 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.808 0.192 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.807 0.193 0.000
I25.2 Old myocardial infarction
0.805 0.195 0.000
I34.0 Mitral (valve) insufficiency
0.804 0.196 0.000
E50-E64 Other nutritional deficiencies
0.803 0.197 0.000
Z96.6 Presence of orthopaedic joint implants
0.802 0.198 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.801 0.199 0.000
Z43 Attention to artificial openings
0.801 0.199 0.000
M31.3 Wegener's granulomatosis
0.800 0.200 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.800 0.200 0.000
M50-M54 Other dorsopathies
0.799 0.201 0.000
Z53.9 Procedure not carried out, unspecified reason
0.799 0.201 0.000
M81.9 Osteoporosis, unspecified
0.798 0.202 0.000
Z51.8 Other specified medical care
0.797 0.203 0.000
J90-J94 Other diseases of pleura
0.795 0.205 0.000
M80 Osteoporosis with pathological fracture
0.793 0.207 0.000
Z50.8 Care involving use of rehabilitation procedures
0.793 0.207 0.000
V80-V89 Other land transport accidents
0.793 0.207 0.000
Z91.5 Personal history of self-harm
0.792 0.208 0.000
G35 Multiple sclerosis
0.791 0.209 0.000
Z96.1 Presence of intraocular lens
0.791 0.209 0.000
Z92.3 Personal history of irradiation
0.788 0.212 0.000
Chapter V Mental and behavioural disorders
0.787 0.213 0.000
S09 Other and unspecified injuries of head
0.786 0.214 0.000
Z46 Fitting and adjustment of other devices
0.785 0.215 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.783 0.217 0.000
J30-J39 Other diseases of upper respiratory tract
0.782 0.218 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.781 0.219 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.779 0.221 0.000
J84 Other interstitial pulmonary diseases
0.776 0.224 0.000
M13.9 Arthritis, unspecified
0.776 0.224 0.000
Z45 Adjustment and management of implanted device
0.776 0.224 0.000
Z51.2 Other chemotherapy
0.776 0.224 0.000
M60-M63 Disorders of muscles
0.775 0.225 0.000
W19 Unspecified fall
0.775 0.225 0.000
E86 Volume depletion
0.774 0.226 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.774 0.226 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.774 0.226 0.000
M25.7 Osteophyte
0.771 0.229 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.770 0.230 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.770 0.230 0.000
A00-A09 Intestinal infectious diseases
0.768 0.232 0.000
Z54 Convalescence
0.765 0.235 0.000
G40 Epilepsy
0.764 0.236 0.000
S80-S89 Injuries to the knee and lower leg
0.764 0.236 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.764 0.236 0.000
I44.7 Left bundle-branch block, unspecified
0.763 0.237 0.000
M21 Other acquired deformities of limbs
0.763 0.237 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.762 0.238 0.000
H05 Disorders of orbit
0.761 0.239 0.000
H10-H13 Disorders of conjunctiva
0.760 0.240 0.000
Z49 Care involving dialysis
0.758 0.242 0.000
M40-M43 Deforming dorsopathies
0.757 0.243 0.000
M84 Disorders of continuity of bone
0.757 0.243 0.000
M15-M19 Arthrosis
0.756 0.243 0.000
S90-S99 Injuries to the ankle and foot
0.756 0.244 0.000
Z94 Transplanted organ and tissue status
0.756 0.244 0.000
E65-E68 Obesity and other hyperalimentation
0.755 0.245 0.000
S20-S29 Injuries to the thorax
0.755 0.245 0.000
M86-M90 Other osteopathies
0.755 0.245 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.754 0.245 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.753 0.246 0.000
J43 Emphysema
0.752 0.248 0.000
I51.8 Other ill-defined heart diseases
0.751 0.249 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.751 0.249 0.000
M35.3 Polymyalgia rheumatica
0.750 0.250 0.000
R42 Dizziness and giddiness
0.749 0.251 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.749 0.251 0.000
S00 Superficial injury of head
0.748 0.252 0.000
H30-H36 Disorders of choroid and retina
0.748 0.252 0.000
Z93.1 Gastrostomy status
0.748 0.252 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.747 0.253 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.746 0.254 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.746 0.254 0.000
H40-H42 Glaucoma
0.746 0.254 0.000
M65-M68 Disorders of synovium and tendon
0.745 0.255 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.744 0.256 0.000
M50 Cervical disk disorders
0.743 0.256 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.742 0.258 0.000
I42.0 Dilated cardiomyopathy
0.741 0.259 0.000
Z51.5 Palliative care
0.740 0.260 0.000
Chapter XXII Codes for special purposes
0.740 0.260 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.740 0.260 0.000
I26 Pulmonary embolism
0.739 0.261 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.738 0.262 0.000
H55-H59 Other disorders of eye and adnexa
0.738 0.262 0.000
Z52 Donors of organs and tissues
0.738 0.262 0.000
Y40 Systemic antibiotics
0.737 0.263 0.000
I35 Nonrheumatic aortic valve disorders
0.736 0.263 0.000
E20-E35 Disorders of other endocrine glands
0.734 0.266 0.000
I95.9 Hypotension, unspecified
0.734 0.266 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.734 0.266 0.000
Y83.8 Other surgical procedures
0.734 0.266 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.733 0.267 0.000
R50 Fever of unknown origin
0.733 0.267 0.000
X60-X84 Intentional self-harm
0.731 0.269 0.000
M31.6 Other giant cell arteritis
0.731 0.269 0.000
R61 Hyperhidrosis
0.729 0.270 0.000
I50.1 Left ventricular failure
0.729 0.271 0.000
S52 Fracture of forearm
0.728 0.272 0.000
J18.0 Bronchopneumonia, unspecified
0.727 0.273 0.000
W19.9 Unspecified place
0.726 0.274 0.000
M85 Other disorders of bone density and structure
0.726 0.274 0.000
R52 Pain, not elsewhere classified
0.726 0.274 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.726 0.274 0.000
Z96.8 Presence of other specified functional implants
0.726 0.274 0.000
E00-E07 Disorders of thyroid gland
0.725 0.275 0.000
J95-J99 Other diseases of the respiratory system
0.725 0.275 0.000
E83.5 Disorders of calcium metabolism
0.725 0.275 0.000
S09.9 Unspecified injury of head
0.724 0.276 0.000
I42.2 Other hypertrophic cardiomyopathy
0.724 0.276 0.000
Z96.7 Presence of other bone and tendon implants
0.723 0.277 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.722 0.278 0.000
M24 Other specific joint derangements
0.720 0.280 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.720 0.280 0.000
G37 Other demyelinating diseases of central nervous system
0.720 0.280 0.000
G20 Parkinson's disease
0.720 0.280 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.719 0.281 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.719 0.281 0.000
Y86 Sequelae of other accidents
0.719 0.281 0.000
G90-G99 Other disorders of the nervous system
0.718 0.281 0.000
J60-J70 Lung diseases due to external agents
0.718 0.282 0.000
I95.1 Orthostatic hypotension
0.718 0.282 0.000
Z90.3 Acquired absence of part of stomach
0.718 0.282 0.000
Z98 Other postsurgical states
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.283 0.000
T86 Failure and rejection of transplanted organs and tissues
0.716 0.283 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.283 0.000
S70-S79 Injuries to the hip and thigh
0.716 0.283 0.000
I34.1 Mitral (valve) prolapse
0.716 0.284 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
Y00-Y09 Assault
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X20-X29 Contact with venomous animals and plants
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
W50-W64 Exposure to animate mechanical forces
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V40-V49 Car occupant injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V20-V29 Motorcycle rider injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
Z97 Presence of other devices
0.713 0.287 0.000
Z89 Acquired absence of limb
0.713 0.287 0.000
Z84 Family history of other conditions
0.713 0.287 0.000
Z81 Family history of mental and behavioural disorders
0.713 0.287 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I37 Pulmonary valve disorders
0.713 0.287 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
I30 Acute pericarditis
0.713 0.287 0.000
R40.2 Coma, unspecified
0.712 0.288 0.000
M48 Other spondylopathies
0.712 0.288 0.000
Z91.6 Personal history of other physical trauma
0.711 0.289 0.000
G70-G73 Diseases of myoneural junction and muscle
0.711 0.289 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.711 0.289 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.711 0.289 0.000
E87.6 Hypokalaemia
0.711 0.289 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.711 0.289 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.710 0.290 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.710 0.290 0.000
T66-T78 Other and unspecified effects of external causes
0.710 0.290 0.000
Z93.0 Tracheostomy status
0.709 0.291 0.000
G43 Migraine
0.708 0.292 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.708 0.292 0.000
E87.7 Fluid overload
0.707 0.293 0.000
I50.9 Heart failure, unspecified
0.706 0.294 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.704 0.296 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.703 0.296 0.000
M34 Systemic sclerosis
0.703 0.296 0.000
M33 Dermatopolymyositis
0.703 0.296 0.000
M32 Systemic lupus erythematosus
0.703 0.296 0.000
M30 Polyarteritis nodosa and related conditions
0.703 0.296 0.000
Z42 Follow-up care involving plastic surgery
0.703 0.297 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.703 0.297 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.703 0.297 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.703 0.297 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.703 0.297 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.703 0.297 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.701 0.299 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.701 0.299 0.000
R57 Shock, not elsewhere classified
0.700 0.300 0.000
Z90.1 Acquired absence of breast(s)
0.700 0.300 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.700 0.300 0.000
M23.4 Loose body in knee
0.698 0.302 0.000
Z48 Other surgical follow-up care
0.698 0.302 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.697 0.303 0.000
T81.9 Unspecified complication of procedure
0.697 0.303 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.697 0.303 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.697 0.303 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.697 0.303 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.697 0.303 0.000
T39.1 4-Aminophenol derivatives
0.696 0.304 0.000
M45 Ankylosing spondylitis
0.696 0.304 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.694 0.306 0.000
H90-H95 Other disorders of ear
0.694 0.306 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.694 0.306 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.693 0.307 0.000
M46 Other inflammatory spondylopathies
0.693 0.307 0.000
Z95.4 Presence of other heart-valve replacement
0.692 0.307 0.000
H25-H28 Disorders of lens
0.692 0.308 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.692 0.308 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.692 0.308 0.000
Y45.0 Opioids and related analgesics
0.692 0.308 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.692 0.308 0.000
E65 Localised adiposity
0.691 0.309 0.000
I38 Endocarditis, valve unspecified
0.691 0.309 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.691 0.309 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.690 0.310 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.690 0.310 0.000
E87.5 Hyperkalaemia
0.689 0.310 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.689 0.311 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.688 0.312 0.000
H65-H75 Diseases of middle ear and mastoid
0.688 0.312 0.000
Z92.0 Personal history of contraception
0.688 0.312 0.000
E40-E46 Malnutrition
0.687 0.312 0.000
W20-W49 Exposure to inanimate mechanical forces
0.687 0.313 0.000
R40.0 Somnolence
0.687 0.313 0.000
V10-V19 Pedal cyclist injured in transport accident
0.686 0.313 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.686 0.314 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.685 0.315 0.000
Z95.3 Presence of xenogenic heart valve
0.685 0.315 0.000
J20-J22 Other acute lower respiratory infections
0.685 0.315 0.000
I31.9 Disease of pericardium, unspecified
0.685 0.315 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.685 0.315 0.000
G47 Sleep disorders
0.685 0.315 0.000
Y44 Agents primarily affecting blood constituents
0.684 0.316 0.000
M83 Adult osteomalacia
0.684 0.316 0.000
M82 Osteoporosis in diseases classified elsewhere
0.684 0.316 0.000
J17 Pneumonia in diseases classified elsewhere
0.683 0.317 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.683 0.317 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.683 0.317 0.000
J12 Viral pneumonia, not elsewhere classified
0.683 0.317 0.000
J11 Influenza, virus not identified
0.683 0.317 0.000
J10 Influenza due to identified influenza virus
0.683 0.317 0.000
J14 Pneumonia due to Haemophilus influenzae
0.683 0.317 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.683 0.317 0.000
J09 Influenza due to certain identified influenza virus
0.683 0.317 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.683 0.317 0.000
I33.0 Acute and subacute infective endocarditis
0.682 0.318 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.682 0.318 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.682 0.318 0.000
G30 Alzheimer's disease
0.681 0.319 0.000
G25 Other extrapyramidal and movement disorders
0.681 0.319 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.680 0.320 0.000
I46 Cardiac arrest
0.680 0.320 0.000
H60-H62 Diseases of external ear
0.680 0.320 0.000
R60 Oedema, not elsewhere classified
0.680 0.320 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.679 0.321 0.000
M77 Other enthesopathies
0.678 0.322 0.000
H53-H54 Visual disturbances and blindness
0.677 0.323 0.000
G40.9 Epilepsy, unspecified
0.676 0.324 0.000
Y83.3 Surgical operation with formation of external stoma
0.676 0.324 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.676 0.324 0.000
A30-A49 Other bacterial diseases
0.675 0.325 0.000
J93 Pneumothorax
0.675 0.325 0.000
M22 Disorders of patella
0.675 0.325 0.000
M50.2 Other cervical disk displacement
0.675 0.325 0.000
Z50.6 Orthoptic training
0.674 0.325 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.674 0.325 0.000
Z50.3 Drug rehabilitation
0.674 0.325 0.000
I08 Multiple valve diseases
0.674 0.326 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.673 0.327 0.000
Z91.7 Personal history of female genital mutilation
0.673 0.327 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.673 0.327 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.673 0.327 0.000
Z91.2 Personal history of poor personal hygiene
0.673 0.327 0.000
M79.0 Rheumatism, unspecified
0.673 0.327 0.000
M49 Spondylopathies in diseases classified elsewhere
0.673 0.327 0.000
Z51.9 Medical care, unspecified
0.673 0.327 0.000
Z51.6 Desensitisation to allergens
0.673 0.327 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.672 0.328 0.000
Z50.2 Alcohol rehabilitation
0.672 0.328 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.672 0.328 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.672 0.328 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.672 0.328 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.672 0.328 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.672 0.328 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.672 0.328 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.672 0.328 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.672 0.328 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.672 0.328 0.000
T36 Poisoning by systemic antibiotics
0.672 0.328 0.000
M47.2 Other spondylosis with radiculopathy
0.671 0.329 0.000
Y83.9 Surgical procedure, unspecified
0.671 0.329 0.000
I24 Other acute ischaemic heart diseases
0.671 0.329 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.670 0.330 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.670 0.330 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.670 0.330 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.670 0.330 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.670 0.330 0.000
H04 Disorders of lachrymal system
0.669 0.330 0.000
Z22 Carrier of infectious disease
0.669 0.331 0.000
R56 Convulsions, not elsewhere classified
0.669 0.331 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.669 0.331 0.000
I42.9 Cardiomyopathy, unspecified
0.669 0.331 0.000
S00.8 Superficial injury of other parts of head
0.669 0.331 0.000
L60-L75 Disorders of skin appendages
0.669 0.331 0.000
I31.3 Pericardial effusion (noninflammatory)
0.668 0.332 0.000
J34 Other disorders of nose and nasal sinuses
0.667 0.332 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.667 0.333 0.000
Z93.6 Other artificial openings of urinary tract status
0.666 0.334 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.665 0.334 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.665 0.335 0.000
Z87 Personal history of other diseases and conditions
0.664 0.336 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.663 0.337 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.663 0.337 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.662 0.338 0.000
J47 Bronchiectasis
0.662 0.338 0.000
Z93.9 Artificial opening status, unspecified
0.662 0.338 0.000
Z93.8 Other artificial opening status
0.662 0.338 0.000
Z93.5 Cystostomy status
0.662 0.338 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.662 0.338 0.000
R68 Other general symptoms and signs
0.662 0.338 0.000
Y83.5 Amputation of limb(s)
0.662 0.338 0.000
Y83.0 Surgical operation with transplant of whole organ
0.662 0.338 0.000
J18.8 Other pneumonia, organism unspecified
0.661 0.339 0.000
J18.2 Hypostatic pneumonia, unspecified
0.661 0.339 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.661 0.339 0.000
H01.9 Inflammation of eyelid, unspecified
0.660 0.340 0.000
H01.8 Other specified inflammation of eyelid
0.660 0.340 0.000
H01.1 Non-infectious dermatoses of eyelid
0.660 0.340 0.000
E88 Other metabolic disorders
0.659 0.341 0.000
E87.0 Hyperosmolality and hypernatraemia
0.658 0.342 0.000
I44.0 Atrioventricular block, first degree
0.657 0.343 0.000
M13.98 Arthritis, unspecified (Other)
0.657 0.343 0.000
J41 Simple and mucopurulent chronic bronchitis
0.657 0.343 0.000
J42 Unspecified chronic bronchitis
0.657 0.343 0.000
M25.4 Effusion of joint
0.657 0.343 0.000
E85 Amyloidosis
0.656 0.344 0.000
E84 Cystic fibrosis
0.656 0.344 0.000
E79 Disorders of purine and pyrimidine metabolism
0.656 0.344 0.000
E77 Disorders of glycoprotein metabolism
0.656 0.344 0.000
E76 Disorders of glycosaminoglycan metabolism
0.656 0.344 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.656 0.344 0.000
E74 Other disorders of carbohydrate metabolism
0.656 0.344 0.000
E73 Lactose intolerance
0.656 0.344 0.000
E72 Other disorders of amino-acid metabolism
0.656 0.344 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.656 0.344 0.000
E70 Disorders of aromatic amino-acid metabolism
0.656 0.344 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.656 0.344 0.000
Z96.9 Presence of functional implant, unspecified
0.656 0.344 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.656 0.344 0.000
Z96.4 Presence of endocrine implants
0.656 0.344 0.000
Z96.3 Presence of artificial larynx
0.656 0.344 0.000
Z96.2 Presence of otological and audiological implants
0.656 0.344 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.655 0.344 0.000
R62 Lack of expected normal physiological development
0.655 0.344 0.000
R64 Cachexia
0.655 0.344 0.000
R58 Haemorrhage, not elsewhere classified
0.655 0.344 0.000
Z47.8 Other specified orthopaedic follow-up care
0.655 0.344 0.000
M47.8 Other spondylosis
0.655 0.345 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.655 0.345 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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