TreeWAS – Variant ID: rs4821318

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
E70-E90 Metabolic disorders	1.000	0.000
Chapter I Certain infectious and parasitic diseases	0.999	0.001
E87 Other disorders of fluid, electrolyte and acid-base balance	0.998	0.002
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.996	0.004
E87.5 Hyperkalaemia	0.992	0.008
B95-B98 Bacterial, viral and other infectious agents	0.990	0.010
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.988	0.012
Chapter VII Diseases of the eye and adnexa	0.982	0.018
Chapter VIII Diseases of the ear and mastoid process	0.977	0.023
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.977	0.023
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.976	0.024
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.974	0.026
D10-D36 Benign neoplasms	0.971	0.029
Chapter XX External causes of morbidity and mortality	0.971	0.029
C64-C68 Malignant neoplasms of urinary tract	0.971	0.029
E89.0 Postprocedural hypothyroidism	0.961	0.039
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.956	0.044
E10-E14 Diabetes mellitus	0.954	0.046
H80-H83 Diseases of inner ear	0.954	0.046
E86 Volume depletion	0.954	0.046
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.952	0.048
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.950	0.050
A30-A49 Other bacterial diseases	0.947	0.053
Chapter XV Pregnancy, childbirth and the puerperium	0.947	0.053
C85.1 B-cell lymphoma, unspecified	0.933	0.067
C60-C63 Malignant neoplasms of male genital organs	0.924	0.076
E11 Non-insulin-dependent diabetes mellitus	0.924	0.076
H18 Other disorders of cornea	0.921	0.079
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.921	0.079
H65-H75 Diseases of middle ear and mastoid	0.920	0.080
E87.0 Hyperosmolality and hypernatraemia	0.919	0.081
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.918	0.082
H81 Disorders of vestibular function	0.917	0.083
C67 Malignant neoplasm of bladder	0.916	0.084
A41 Other septicaemia	0.914	0.086
B25-B34 Other viral diseases	0.913	0.087
E87.2 Acidosis	0.911	0.089
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.902	0.098
D22 Melanocytic naevi	0.897	0.103
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.894	0.106
A41.9 Septicaemia, unspecified	0.889	0.111
H21 Other disorders of iris and ciliary body	0.888	0.112
D14 Benign neoplasm of middle ear and respiratory system	0.886	0.114
C81 Hodgkin's disease	0.882	0.118
D37-D48 Neoplasms of uncertain or unknown behaviour	0.882	0.118
D70-D77 Other diseases of blood and blood-forming organs	0.882	0.118
H81.0 Meniere's disease	0.881	0.119
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.876	0.124
C62 Malignant neoplasm of testis	0.874	0.126
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.872	0.128
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.872	0.128
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.870	0.130
H65 Nonsuppurative otitis media	0.866	0.134
W00-W19 Falls	0.864	0.136
D34 Benign neoplasm of thyroid gland	0.863	0.137
B34 Viral infection of unspecified site	0.861	0.139
E88 Other metabolic disorders	0.859	0.141
O00-O08 Pregnancy with abortive outcome	0.857	0.143
D22.5 Melanocytic naevi of trunk	0.853	0.147
H46-H48 Disorders of optic nerve and visual pathways	0.851	0.148
B07 Viral warts	0.851	0.149
E11.4 With neurological complications	0.851	0.149
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.850	0.150
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.848	0.152
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.844	0.156
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.843	0.157
C62.9 Testis, unspecified	0.838	0.162
C67.9 Bladder, unspecified	0.837	0.163
O60-O75 Complications of labour and delivery	0.837	0.163
C64 Malignant neoplasm of kidney, except renal pelvis	0.836	0.164
C73 Malignant neoplasm of thyroid gland	0.832	0.168
Chapter VI Diseases of the nervous system	0.829	0.171
D27 Benign neoplasm of ovary	0.826	0.174
D17 Benign lipomatous neoplasm	0.824	0.176
D70 Agranulocytosis	0.823	0.177
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.819	0.181
Chapter XXII Codes for special purposes	0.814	0.186
C92 Myeloid leukaemia	0.813	0.187
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.811	0.189
B34.9 Viral infection, unspecified	0.809	0.191
E11.9 Without complications	0.803	0.197
C81.9 Hodgkin's disease, unspecified	0.801	0.199
H20 Iridocyclitis	0.800	0.199
D13.1 Stomach	0.800	0.200
H40-H42 Glaucoma	0.799	0.201
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.798	0.202
D14.0 Middle ear, nasal cavity and accessory sinuses	0.797	0.203
Y44 Agents primarily affecting blood constituents	0.797	0.203
D60-D64 Aplastic and other anaemias	0.796	0.204
O85-O92 Complications predominantly related to the puerperium	0.795	0.205
E87.3 Alkalosis	0.793	0.207
C91 Lymphoid leukaemia	0.787	0.213
H80 Otosclerosis	0.787	0.213
Y52 Agents primarily affecting the cardiovascular system	0.786	0.214
D12.8 Rectum	0.786	0.214
E13 Other specified diabetes mellitus	0.782	0.218
O68 Labour and delivery complicated by foetal stress [distress]	0.782	0.218
H18.2 Other corneal oedema	0.779	0.221
H16 Keratitis	0.779	0.221
Chapter X Diseases of the respiratory system	0.776	0.224
A41.5 Septicaemia due to other Gram-negative organisms	0.776	0.224
H65.2 Chronic serous otitis media	0.776	0.224
H71 Cholesteatoma of middle ear	0.774	0.226
H65.4 Other chronic nonsuppurative otitis media	0.772	0.228
G20-G26 Extrapyramidal and movement disorders	0.771	0.229
D35 Benign neoplasm of other and unspecified endocrine glands	0.770	0.230
H18.4 Corneal degeneration	0.769	0.231
H18.6 Keratoconus	0.766	0.234
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.766	0.234
E11.5 With peripheral circulatory complications	0.765	0.235
H21.2 Degeneration of iris and ciliary body	0.761	0.239
D22.9 Melanocytic naevi, unspecified	0.760	0.240
E20-E35 Disorders of other endocrine glands	0.760	0.240
W18 Other fall on same level	0.759	0.241
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.758	0.242
C66 Malignant neoplasm of ureter	0.756	0.244
B97 Viral agents as the cause of diseases classified to other chapters	0.756	0.244
H83 Other diseases of inner ear	0.755	0.245
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.755	0.245
C51-C58 Malignant neoplasms of female genital organs	0.752	0.247
H81.9 Disorder of vestibular function, unspecified	0.750	0.250
H17 Corneal scars and opacities	0.749	0.251
O69 Labour and delivery complicated by umbilical cord complications	0.748	0.252
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.748	0.252
B00 Herpesviral [herpes simplex] infections	0.747	0.253
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.747	0.253
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.747	0.253
V10-V19 Pedal cyclist injured in transport accident	0.746	0.254
H46 Optic neuritis	0.746	0.254
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.745	0.255
V40-V49 Car occupant injured in transport accident	0.745	0.255
D22.1 Melanocytic naevi of eyelid, including canthus	0.742	0.258
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.738	0.262
Y51 Drugs primarily affecting the autonomic nervous system	0.738	0.262
H00 Hordeolum and chalazion	0.737	0.263
Y42.7 Androgens and anabolic congeners	0.737	0.263
E11.6 With other specified complications	0.734	0.266
D16 Benign neoplasm of bone and articular cartilage	0.733	0.267
Y42.5 Other oestrogens and progestogens	0.731	0.269
D28 Benign neoplasm of other and unspecified female genital organs	0.731	0.269
O03 Spontaneous abortion	0.730	0.270
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.730	0.270
B20-B24 Human immunodeficiency virus [HIV] disease	0.730	0.270
D30 Benign neoplasm of urinary organs	0.730	0.270
W07 Fall involving chair	0.729	0.271
Y43 Primarily systemic agents	0.729	0.271
H21.8 Other specified disorders of iris and ciliary body	0.728	0.272
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.728	0.272
Y40 Systemic antibiotics	0.726	0.274
E73 Lactose intolerance	0.725	0.274
D69 Purpura and other haemorrhagic conditions	0.725	0.275
D10 Benign neoplasm of mouth and pharynx	0.724	0.275
D12.2 Ascending colon	0.724	0.276
C67.4 Posterior wall of bladder	0.722	0.278
H81.2 Vestibular neuronitis	0.722	0.278
Y41 Other systemic anti-infectives and antiparasitics	0.721	0.279
Y49 Psychotropic drugs, not elsewhere classified	0.721	0.279
B65-B83 Helminthiases	0.720	0.279
H18.9 Disorder of cornea, unspecified	0.720	0.280
O32 Maternal care for known or suspected malpresentation of foetus	0.719	0.281
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
E85 Amyloidosis	0.717	0.283
E84 Cystic fibrosis	0.717	0.283
E79 Disorders of purine and pyrimidine metabolism	0.717	0.283
E77 Disorders of glycoprotein metabolism	0.717	0.283
E76 Disorders of glycosaminoglycan metabolism	0.717	0.283
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.717	0.283
E74 Other disorders of carbohydrate metabolism	0.717	0.283
E72 Other disorders of amino-acid metabolism	0.717	0.283
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.717	0.283
E70 Disorders of aromatic amino-acid metabolism	0.717	0.283
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.717	0.283
Y00-Y09 Assault	0.717	0.283
B99-B99 Other infectious diseases	0.716	0.284
B85-B89 Pediculosis, acariasis and other infestations	0.716	0.284
B50-B64 Protozoal diseases	0.716	0.284
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.716	0.284
A75-A79 Rickettsioses	0.716	0.284
A70-A74 Other diseases caused by chlamydiae	0.716	0.284
A65-A69 Other spirochaetal diseases	0.716	0.284
A20-A28 Certain zoonotic bacterial diseases	0.716	0.284
A15-A19 Tuberculosis	0.716	0.284
H73 Other disorders of tympanic membrane	0.716	0.284
E87.4 Mixed disorder of acid-base balance	0.716	0.284
D14.3 Bronchus and lung	0.715	0.285
E87.7 Fluid overload	0.715	0.285
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.715	0.285
W50-W64 Exposure to animate mechanical forces	0.715	0.285
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.714	0.286
C95 Leukaemia of unspecified cell type	0.714	0.286
C94 Other leukaemias of specified cell type	0.714	0.286
C93 Monocytic leukaemia	0.714	0.286
C88 Malignant immunoproliferative diseases	0.714	0.286
C86 Other specified types of T/NK-cell lymphoma	0.714	0.286
C84 Peripheral and cutaneous T-cell lymphomas	0.714	0.286
A48 Other bacterial diseases, not elsewhere classified	0.712	0.288
D61 Other aplastic anaemias	0.712	0.288
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.710	0.290
X58-X59 Accidental exposure to other and unspecified factors	0.710	0.290
C67.6 Ureteric orifice	0.709	0.291
C85.7 Other specified types of non-Hodgkin's lymphoma	0.708	0.292
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.708	0.292
C85.0 Lymphosarcoma	0.708	0.292
Q00-Q07 Congenital malformations of the nervous system	0.707	0.293
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.707	0.293
E10 Insulin-dependent diabetes mellitus	0.707	0.293
B35-B49 Mycoses	0.703	0.297
O61 Failed induction of labour	0.703	0.297
C83 Diffuse non-Hodgkin's lymphoma	0.702	0.298
C49 Malignant neoplasm of other connective and soft tissue	0.702	0.298
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.702	0.298
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.701	0.299
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.700	0.299
E89.8 Other postprocedural endocrine and metabolic disorders	0.700	0.299
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.700	0.299
E89.5 Postprocedural testicular hypofunction	0.700	0.299
E89.4 Postprocedural ovarian failure	0.700	0.299
E89.3 Postprocedural hypopituitarism	0.700	0.299
E89.2 Postprocedural hypoparathyroidism	0.700	0.299
E89.1 Postprocedural hypoinsulinaemia	0.700	0.299
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.700	0.300
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.700	0.300
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.700	0.300
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.700	0.300
H18.8 Other specified disorders of cornea	0.700	0.300
X60-X84 Intentional self-harm	0.699	0.301
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.698	0.301
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.698	0.301
H15 Disorders of sclera	0.698	0.301
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.698	0.302
H55-H59 Other disorders of eye and adnexa	0.697	0.302
B01 Varicella [chickenpox]	0.697	0.303
H21.5 Other adhesions and disruptions of iris and ciliary body	0.697	0.303
D31 Benign neoplasm of eye and adnexa	0.696	0.303
D29 Benign neoplasm of male genital organs	0.696	0.303
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.696	0.303
D19 Benign neoplasm of mesothelial tissue	0.696	0.303
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.696	0.303
Y35-Y36 Legal intervention and operations of war	0.696	0.304
Y10-Y34 Event of undetermined intent	0.696	0.304
X85-X99 Assault	0.696	0.304
X50-X57 Overexertion, travel and privation	0.696	0.304
X30-X39 Exposure to forces of nature	0.696	0.304
X10-X19 Contact with heat and hot substances	0.696	0.304
X00-X09 Exposure to smoke, fire and flames	0.696	0.304
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.696	0.304
W75-W84 Other accidental threats to breathing	0.696	0.304
W65-W74 Accidental drowning and submersion	0.696	0.304
V98-V99 Other and unspecified transport accidents	0.696	0.304
V95-V97 Air and space transport accidents	0.696	0.304
V90-V94 Water transport accidents	0.696	0.304
V70-V79 Bus occupant injured in transport accident	0.696	0.304
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.696	0.304
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.696	0.304
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.696	0.304
V01-V09 Pedestrian injured in transport accident	0.696	0.304
C68 Malignant neoplasm of other and unspecified urinary organs	0.696	0.304
C65 Malignant neoplasm of renal pelvis	0.696	0.304
E00-E07 Disorders of thyroid gland	0.695	0.305
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.694	0.306
O48 Prolonged pregnancy	0.693	0.307
D72 Other disorders of white blood cells	0.693	0.307
C67.2 Lateral wall of bladder	0.692	0.308
G40-G47 Episodic and paroxysmal disorders	0.692	0.308
E83 Disorders of mineral metabolism	0.691	0.309
D25 Leiomyoma of uterus	0.691	0.309
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.691	0.309
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.690	0.310
O02 Other abnormal products of conception	0.689	0.311
O73 Retained placenta and membranes, without haemorrhage	0.687	0.313
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.687	0.313
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.686	0.314
W19 Unspecified fall	0.686	0.314
B34.8 Other viral infections of unspecified site	0.685	0.315
Y44.2 Anticoagulants	0.685	0.315
E12 Malnutrition-related diabetes mellitus	0.684	0.316
W18.3 Sports and athletics area	0.684	0.316
H82 Vertiginous syndromes in diseases classified elsewhere	0.684	0.316
H01 Other inflammation of eyelid	0.683	0.317
Y59 Other and unspecified vaccines and biological substances	0.683	0.317
Y58 Bacterial vaccines	0.683	0.317
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.683	0.317
Y53 Agents primarily affecting the gastro-intestinal system	0.683	0.317
Y50 Central nervous system stimulants, not elsewhere classified	0.683	0.317
Y48 Anaesthetics and therapeutic gases	0.683	0.317
Y47 Sedatives, hypnotics and antianxiety drugs	0.683	0.317
Y46 Antiepileptics and anti-Parkinsonism drugs	0.683	0.317
C92.0 Acute myeloid leukaemia	0.682	0.318
O90 Complications of the puerperium, not elsewhere classified	0.682	0.318
D55-D59 Haemolytic anaemias	0.681	0.319
O04 Medical abortion	0.681	0.319
G24 Dystonia	0.681	0.319
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.680	0.319
X20-X29 Contact with venomous animals and plants	0.680	0.320
E11.1 With ketoacidosis	0.680	0.320
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.679	0.321
A44 Bartonellosis	0.679	0.321
A43 Nocardiosis	0.679	0.321
A42 Actinomycosis	0.679	0.321
A40 Streptococcal septicaemia	0.679	0.321
A39 Meningococcal infection	0.679	0.321
A37 Whooping cough	0.679	0.321
A36 Diphtheria	0.679	0.321
A32 Listeriosis	0.679	0.321
A31 Infection due to other mycobacteria	0.679	0.321
A30 Leprosy [Hansen's disease]	0.679	0.321
A46 Erysipelas	0.679	0.321
A38 Scarlet fever	0.679	0.321
A35 Other tetanus	0.679	0.321
A34 Obstetrical tetanus	0.679	0.321
A33 Tetanus neonatorum	0.679	0.321
Q60-Q64 Congenital malformations of the urinary system	0.678	0.322
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.677	0.323
Y42.0 Glucocorticoids and synthetic analogs	0.677	0.323
Chapter IX Diseases of the circulatory system	0.676	0.324
H20.9 Iridocyclitis, unspecified	0.676	0.324
C56 Malignant neoplasm of ovary	0.672	0.328
D68 Other coagulation defects	0.672	0.328
E11.0 With coma	0.672	0.328
O03.4 Incomplete, without complication	0.671	0.329
Y60-Y69 Misadventures to patients during surgical and medical care	0.670	0.330
O20-O29 Other maternal disorders predominantly related to pregnancy	0.669	0.331
D12.3 Transverse colon	0.669	0.331
D73 Diseases of spleen	0.668	0.331
V80-V89 Other land transport accidents	0.667	0.333
C91.4 Hairy-cell leukaemia	0.667	0.333
H80.9 Otosclerosis, unspecified	0.667	0.333
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.667	0.333
H40 Glaucoma	0.667	0.333
G70-G73 Diseases of myoneural junction and muscle	0.666	0.334
H02 Other disorders of eyelid	0.666	0.334
A41.1 Septicaemia due to other specified staphylococcus	0.666	0.334
A80-A89 Viral infections of the central nervous system	0.665	0.334
D80-D89 Certain disorders involving the immune mechanism	0.665	0.335
D69.6 Thrombocytopenia, unspecified	0.665	0.335
H65.3 Chronic mucoid otitis media	0.664	0.336
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.664	0.336
H05 Disorders of orbit	0.664	0.336
J40-J47 Chronic lower respiratory diseases	0.664	0.336
X40-X49 Accidental poisoning by and exposure to noxious substances	0.664	0.336
C63 Malignant neoplasm of other and unspecified male genital organs	0.663	0.337
C60 Malignant neoplasm of penis	0.663	0.337
E11.8 With unspecified complications	0.663	0.337
E11.7 With multiple complications	0.663	0.337
E80 Disorders of porphyrin and bilirubin metabolism	0.661	0.338
C67.1 Dome of bladder	0.661	0.339
O69.1 Labour and delivery complicated by cord around neck, with compression	0.661	0.339
H18.7 Other corneal deformities	0.660	0.339
H18.3 Changes in corneal membranes	0.660	0.339
H18.1 Bullous keratopathy	0.660	0.339
H18.0 Corneal pigmentations and deposits	0.660	0.339
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.659	0.341
H70 Mastoiditis and related conditions	0.659	0.341
H68 Eustachian salpingitis and obstruction	0.659	0.341
H67 Otitis media in diseases classified elsewhere	0.659	0.341
E13.9 Without complications	0.659	0.341
O41 Other disorders of amniotic fluid and membranes	0.658	0.342
Y52.3 Coronary vasodilators, not elsewhere classified	0.658	0.342
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.658	0.342
B06 Rubella [German measles]	0.658	0.342
B05 Measles	0.658	0.342
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.658	0.342
B04 Monkeypox	0.658	0.342
B03 Smallpox	0.658	0.342
H81.8 Other disorders of vestibular function	0.657	0.343
H81.4 Vertigo of central origin	0.657	0.343
H81.3 Other peripheral vertigo	0.657	0.343
D13.0 Oesophagus	0.657	0.343
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.657	0.343
C67.8 Overlapping lesion of bladder	0.656	0.343
C67.7 Urachus	0.656	0.343
C67.5 Bladder neck	0.656	0.343
C67.3 Anterior wall of bladder	0.656	0.343
C67.0 Trigone of bladder	0.656	0.343
A41.4 Septicaemia due to anaerobes	0.655	0.345
A41.3 Septicaemia due to Haemophilus influenzae	0.655	0.345
A41.2 Septicaemia due to unspecified staphylococcus	0.655	0.345
B33 Other viral diseases, not elsewhere classified	0.655	0.345
B30 Viral conjunctivitis	0.655	0.345
B27 Infectious mononucleosis	0.655	0.345
B26 Mumps	0.655	0.345
D66 Hereditary factor VIII deficiency	0.655	0.345
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.654	0.346
D25.1 Intramural leiomyoma of uterus	0.653	0.347
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.653	0.347
D61.9 Aplastic anaemia, unspecified	0.652	0.348
J90-J94 Other diseases of pleura	0.652	0.348
D22.4 Melanocytic naevi of scalp and neck	0.651	0.349
H04 Disorders of lachrymal system	0.651	0.349
B90-B94 Sequelae of infectious and parasitic diseases	0.651	0.349
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.651	0.349
H10-H13 Disorders of conjunctiva	0.651	0.349
B15-B19 Viral hepatitis	0.649	0.351
H69 Other disorders of Eustachian tube	0.648	0.352
C75 Malignant neoplasm of other endocrine glands and related structures	0.647	0.353
C74 Malignant neoplasm of adrenal gland	0.647	0.353
C61 Malignant neoplasm of prostate	0.645	0.355
D26 Other benign neoplasms of uterus	0.645	0.355
A50-A64 Infections with a predominantly sexual mode of transmission	0.644	0.356
O36 Maternal care for other known or suspected foetal problems	0.643	0.357
D22.2 Melanocytic naevi of ear and external auricular canal	0.643	0.357
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.643	0.357
A41.0 Septicaemia due to Staphylococcus aureus	0.642	0.358
D62 Acute posthaemorrhagic anaemia	0.640	0.360
J95-J99 Other diseases of the respiratory system	0.640	0.360
J44 Other chronic obstructive pulmonary disease	0.640	0.360
H74 Other disorders of middle ear and mastoid	0.639	0.361
H47 Other disorders of optic [2nd] nerve and visual pathways	0.638	0.362
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.638	0.362
D37.7 Other digestive organs	0.637	0.362
H21.9 Disorder of iris and ciliary body, unspecified	0.637	0.363
H21.4 Pupillary membranes	0.637	0.363
H21.3 Cyst of iris, ciliary body and anterior chamber	0.637	0.363
H21.1 Other vascular disorders of iris and ciliary body	0.637	0.363
H21.0 Hyphaema	0.637	0.363
J44.9 Chronic obstructive pulmonary disease, unspecified	0.636	0.364
D14.4 Respiratory system, unspecified	0.635	0.364
D14.2 Trachea	0.635	0.364
D14.1 Larynx	0.635	0.364
E04 Other non-toxic goitre	0.634	0.366
D17.7 Benign lipomatous neoplasm of other sites	0.634	0.366
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.633	0.367
W07.0 Home	0.633	0.367
C81.7 Other Hodgkin's disease	0.633	0.367
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.633	0.367
C81.3 Lymphocytic depletion	0.633	0.367
C81.2 Mixed cellularity	0.633	0.367
C81.1 Nodular sclerosis	0.633	0.367
C81.0 Lymphocytic predominance	0.633	0.367
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.632	0.367
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.632	0.367
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.632	0.367
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.632	0.368
D74 Methaemoglobinaemia	0.632	0.368
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.632	0.368
D71 Functional disorders of polymorphonuclear neutrophils	0.632	0.368
O40 Polyhydramnios	0.631	0.369
G90-G99 Other disorders of the nervous system	0.631	0.369
O80-O84 Delivery	0.631	0.369
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.630	0.370
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.630	0.370
Y57 Other and unspecified drugs and medicaments	0.630	0.370
D33 Benign neoplasm of brain and other parts of central nervous system	0.628	0.371
Q80-Q89 Other congenital malformations	0.629	0.371
D46 Myelodysplastic syndromes	0.628	0.372
Y42.9 Other and unspecified hormone antagonists	0.628	0.372
Y42.4 Oral contraceptives	0.628	0.372
Y42.2 Antithyroid drugs	0.628	0.372
Y42.1 Thyroid hormones and substitutes	0.628	0.372
C62.1 Descended testis	0.626	0.373
C62.0 Undescended testis	0.626	0.373
G20 Parkinson's disease	0.626	0.374
D13.9 Ill-defined sites within the digestive system	0.625	0.375
D13.7 Endocrine pancreas	0.625	0.375
D13.6 Pancreas	0.625	0.375
D13.5 Extrahepatic bile ducts	0.625	0.375
D13.4 Liver	0.625	0.375
D13.3 Other and unspecified parts of small intestine	0.625	0.375
H03 Disorders of eyelid in diseases classified elsewhere	0.625	0.375
V20-V29 Motorcycle rider injured in transport accident	0.625	0.375
Q38-Q45 Other congenital malformations of the digestive system	0.625	0.375
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.624	0.376
H72 Perforation of tympanic membrane	0.622	0.377
E40-E46 Malnutrition	0.622	0.378
H16.9 Keratitis, unspecified	0.621	0.379
H65.1 Other acute nonsuppurative otitis media	0.621	0.379
H65.0 Acute serous otitis media	0.621	0.379
W17 Other fall from one level to another	0.620	0.380
W16 Diving or jumping into water causing injury other than drowning or submersion	0.620	0.380
W15 Fall from cliff	0.620	0.380
W14 Fall from tree	0.620	0.380
W12 Fall on and from scaffolding	0.620	0.380
W11 Fall on and from ladder	0.620	0.380
W09 Fall involving playground equipment	0.620	0.380
W05 Fall involving wheelchair	0.620	0.380
W04 Fall while being carried or supported by other persons	0.620	0.380
W03 Other fall on same level due to collision with, or pushing by, another person	0.620	0.380
W01 Fall on same level from slipping, tripping and stumbling	0.620	0.380
W00 Fall on same level involving ice and snow	0.620	0.380
W08 Fall involving other furniture	0.619	0.381
D12.9 Anus and anal canal	0.619	0.381
H50 Other strabismus	0.618	0.381
G25 Other extrapyramidal and movement disorders	0.618	0.382
B34.4 Papovirus infection, unspecified	0.617	0.383
B34.3 Parvovirus infection, unspecified	0.617	0.383
B34.2 Coronavirus infection, unspecified	0.617	0.383
B34.1 Enterovirus infection, unspecified	0.617	0.383
B34.0 Adenovirus infection, unspecified	0.617	0.383
E88.9 Metabolic disorder, unspecified	0.616	0.384
E88.8 Other specified metabolic disorders	0.616	0.384
E88.3 Tumour lysis syndrome	0.616	0.384
E88.2 Lipomatosis, not elsewhere classified	0.616	0.384
E88.1 Lipodystrophy, not elsewhere classified	0.616	0.384
C02 Malignant neoplasm of other and unspecified parts of tongue	0.615	0.385
O64 Obstructed labour due to malposition and malpresentation of foetus	0.615	0.385
O08 Complications following abortion and ectopic and molar pregnancy	0.615	0.385

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations