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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4977754
log Bayes Factor = 7.24733
Chromosome 9   position 22,062,012  (GRCh37) Explore rs4977754 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.001 0.999
I25.2 Old myocardial infarction
0.000 0.002 0.998
I20.9 Angina pectoris, unspecified
0.000 0.002 0.998
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.010 0.990
I25.1 Atherosclerotic heart disease
0.000 0.015 0.985
I21 Acute myocardial infarction
0.000 0.021 0.979
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.967 0.033 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.041 0.959
Chapter IX Diseases of the circulatory system
0.000 0.043 0.956
S70-S79 Injuries to the hip and thigh
0.951 0.049 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.050 0.950
S50-S59 Injuries to the elbow and forearm
0.947 0.053 0.000
S52 Fracture of forearm
0.931 0.069 0.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.069 0.931
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.071 0.929
I77 Other disorders of arteries and arterioles
0.000 0.077 0.923
I73 Other peripheral vascular diseases
0.000 0.085 0.915
S72 Fracture of femur
0.915 0.085 0.000
Chapter XX External causes of morbidity and mortality
0.910 0.090 0.000
# Top node
0.909 0.091 0.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.096 0.904
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.904 0.096 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.901 0.099 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.899 0.101 0.000
I71 Aortic aneurysm and dissection
0.000 0.102 0.898
Chapter X Diseases of the respiratory system
0.891 0.109 0.000
J30-J39 Other diseases of upper respiratory tract
0.889 0.111 0.000
J33 Nasal polyp
0.880 0.120 0.000
S52.6 Fracture of lower end of both ulna and radius
0.879 0.121 0.000
J33.9 Nasal polyp, unspecified
0.877 0.123 0.000
I77.1 Stricture of artery
0.000 0.124 0.876
J34 Other disorders of nose and nasal sinuses
0.865 0.135 0.000
I05-I09 Chronic rheumatic heart diseases
0.000 0.140 0.860
T36-T50 Poisoning by drugs, medicaments and biological substances
0.849 0.151 0.000
S70 Superficial injury of hip and thigh
0.848 0.151 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.842 0.158 0.000
S80-S89 Injuries to the knee and lower leg
0.839 0.161 0.000
Q50-Q56 Congenital malformations of genital organs
0.838 0.162 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.835 0.165 0.000
S72.0 Fracture of neck of femur
0.833 0.167 0.000
Chapter VIII Diseases of the ear and mastoid process
0.831 0.169 0.000
T92 Sequelae of injuries of upper limb
0.829 0.171 0.000
S52.0 Fracture of upper end of ulna
0.827 0.173 0.000
I70 Atherosclerosis
0.000 0.177 0.823
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.178 0.822
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.183 0.817
S00-S09 Injuries to the head
0.811 0.189 0.000
T66-T78 Other and unspecified effects of external causes
0.809 0.191 0.000
I20.1 Angina pectoris with documented spasm
0.000 0.192 0.808
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.805 0.195 0.000
Y40 Systemic antibiotics
0.804 0.196 0.000
J20-J22 Other acute lower respiratory infections
0.803 0.197 0.000
J34.3 Hypertrophy of nasal turbinates
0.803 0.197 0.000
H65-H75 Diseases of middle ear and mastoid
0.803 0.197 0.000
I08 Multiple valve diseases
0.000 0.199 0.801
T20-T25 Burns and corrosions of external body surface, specified by site
0.800 0.200 0.000
Y57 Other and unspecified drugs and medicaments
0.794 0.206 0.000
Chapter VII Diseases of the eye and adnexa
0.790 0.210 0.000
S72.1 Pertrochanteric fracture
0.788 0.212 0.000
S00 Superficial injury of head
0.785 0.215 0.000
I77.6 Arteritis, unspecified
0.000 0.217 0.783
I20.0 Unstable angina
0.000 0.217 0.783
Y52 Agents primarily affecting the cardiovascular system
0.782 0.218 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.781 0.219 0.000
Y44 Agents primarily affecting blood constituents
0.779 0.221 0.000
H66 Suppurative and unspecified otitis media
0.777 0.223 0.000
J09-J18 Influenza and pneumonia
0.777 0.223 0.000
H33 Retinal detachments and breaks
0.775 0.225 0.000
T92.1 Sequelae of fracture of arm
0.774 0.226 0.000
T79-T79 Certain early complications of trauma
0.774 0.226 0.000
S72.00 Fracture of neck of femur (closed)
0.774 0.226 0.000
I74 Arterial embolism and thrombosis
0.000 0.227 0.773
Q38-Q45 Other congenital malformations of the digestive system
0.773 0.227 0.000
H30-H36 Disorders of choroid and retina
0.771 0.228 0.000
Q51 Congenital malformations of uterus and cervix
0.771 0.229 0.000
D80-D89 Certain disorders involving the immune mechanism
0.771 0.229 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.771 0.229 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.767 0.233 0.000
H33.0 Retinal detachment with retinal break
0.766 0.234 0.000
T91 Sequelae of injuries of neck and trunk
0.759 0.241 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.241 0.759
S00.1 Contusion of eyelid and periocular area
0.754 0.246 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.754 0.246 0.000
S52.5 Fracture of lower end of radius
0.753 0.247 0.000
S20-S29 Injuries to the thorax
0.752 0.248 0.000
H66.9 Otitis media, unspecified
0.750 0.250 0.000
S52.1 Fracture of upper end of radius
0.748 0.252 0.000
S72.3 Fracture of shaft of femur
0.742 0.258 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.741 0.259 0.000
Y40.8 Other systemic antibiotics
0.741 0.259 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.740 0.260 0.000
J22 Unspecified acute lower respiratory infection
0.740 0.260 0.000
H33.3 Retinal breaks without detachment
0.739 0.261 0.000
S10-S19 Injuries to the neck
0.739 0.261 0.000
S59 Other and unspecified injuries of forearm
0.739 0.261 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.738 0.262 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.737 0.263 0.000
I25.3 Aneurysm of heart
0.000 0.263 0.737
V40-V49 Car occupant injured in transport accident
0.737 0.263 0.000
D86 Sarcoidosis
0.736 0.264 0.000
W00-W19 Falls
0.736 0.264 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.735 0.265 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.735 0.265 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.265 0.735
S52.00 Fracture of upper end of ulna (closed)
0.735 0.265 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.734 0.266 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.733 0.267 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.733 0.267 0.000
I24 Other acute ischaemic heart diseases
0.000 0.268 0.732
J10 Influenza due to identified influenza virus
0.732 0.268 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.727 0.273 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.275 0.725
X60-X84 Intentional self-harm
0.725 0.275 0.000
Q51.3 Bicornate uterus
0.723 0.277 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.721 0.279 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.719 0.281 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.719 0.281 0.000
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I25.4 Coronary artery aneurysm
0.000 0.283 0.717
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.283 0.717
L20-L30 Dermatitis and eczema
0.714 0.286 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.714 0.286 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.714 0.286 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.712 0.288 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.712 0.288 0.000
S72.2 Subtrochanteric fracture
0.711 0.289 0.000
Q60-Q64 Congenital malformations of the urinary system
0.711 0.289 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.706 0.294 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
S00.8 Superficial injury of other parts of head
0.705 0.295 0.000
D60-D64 Aplastic and other anaemias
0.704 0.296 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.298 0.702
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.298 0.702
Y00-Y09 Assault
0.702 0.298 0.000
I10-I15 Hypertensive diseases
0.000 0.299 0.701
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.699 0.301 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.301 0.699
Y57.5 X-ray contrast media
0.698 0.302 0.000
J38.5 Laryngeal spasm
0.698 0.302 0.000
S72.10 Pertrochanteric fracture (closed)
0.698 0.302 0.000
Q00-Q07 Congenital malformations of the nervous system
0.696 0.304 0.000
S79 Other and unspecified injuries of hip and thigh
0.694 0.305 0.000
J95-J99 Other diseases of the respiratory system
0.694 0.306 0.000
T33-T35 Frostbite
0.694 0.306 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.694 0.306 0.000
T00-T07 Injuries involving multiple body regions
0.694 0.306 0.000
D86.0 Sarcoidosis of lung
0.691 0.309 0.000
Y44.2 Anticoagulants
0.690 0.310 0.000
L40-L45 Papulosquamous disorders
0.689 0.311 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.312 0.688
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.687 0.313 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.313 0.687
S81 Open wound of lower leg
0.687 0.313 0.000
I00-I02 Acute rheumatic fever
0.000 0.314 0.686
S78 Traumatic amputation of hip and thigh
0.682 0.318 0.000
S77 Crushing injury of hip and thigh
0.682 0.318 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.682 0.318 0.000
S75 Injury of blood vessels at hip and thigh level
0.682 0.318 0.000
S74 Injury of nerves at hip and thigh level
0.682 0.318 0.000
T70 Effects of air pressure and water pressure
0.682 0.318 0.000
Y86 Sequelae of other accidents
0.681 0.319 0.000
S90-S99 Injuries to the ankle and foot
0.680 0.320 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.679 0.321 0.000
S58 Traumatic amputation of forearm
0.679 0.321 0.000
S57 Crushing injury of forearm
0.679 0.321 0.000
S56 Injury of muscle and tendon at forearm level
0.679 0.321 0.000
S55 Injury of blood vessels at forearm level
0.679 0.321 0.000
S54 Injury of nerves at forearm level
0.679 0.321 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.679 0.321 0.000
L29 Pruritus
0.674 0.326 0.000
S50 Superficial injury of forearm
0.672 0.328 0.000
S80 Superficial injury of lower leg
0.671 0.329 0.000
S52.61 Fracture of lower end of both ulna and radius (open)
0.671 0.329 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.671 0.329 0.000
Y43 Primarily systemic agents
0.669 0.331 0.000
S52.9 Fracture of forearm, part unspecified
0.668 0.332 0.000
S52.7 Multiple fractures of forearm
0.668 0.332 0.000
S52.4 Fracture of shafts of both ulna and radius
0.668 0.332 0.000
S52.3 Fracture of shaft of radius
0.668 0.332 0.000
S52.2 Fracture of shaft of ulna
0.668 0.332 0.000
I72 Other aneurysm
0.000 0.335 0.665
S60-S69 Injuries to the wrist and hand
0.663 0.337 0.000
H72 Perforation of tympanic membrane
0.663 0.337 0.000
D61 Other aplastic anaemias
0.663 0.337 0.000
I77.5 Necrosis of artery
0.000 0.338 0.662
I77.4 Coeliac artery compression syndrome
0.000 0.338 0.662
I77.3 Arterial fibromuscular dysplasia
0.000 0.338 0.662
I77.2 Rupture of artery
0.000 0.338 0.662
H40-H42 Glaucoma
0.662 0.338 0.000
V80-V89 Other land transport accidents
0.660 0.339 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.658 0.342 0.000
W19 Unspecified fall
0.657 0.343 0.000
I73.8 Other specified peripheral vascular diseases
0.000 0.344 0.656
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.344 0.656
S72.9 Fracture of femur, part unspecified
0.656 0.344 0.000
S72.8 Fractures of other parts of femur
0.656 0.344 0.000
S72.7 Multiple fractures of femur
0.656 0.344 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.656 0.344 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.344 0.655
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.652 0.347 0.000
Y35-Y36 Legal intervention and operations of war
0.652 0.347 0.000
Y10-Y34 Event of undetermined intent
0.652 0.347 0.000
X85-X99 Assault
0.652 0.347 0.000
X30-X39 Exposure to forces of nature
0.652 0.347 0.000
X10-X19 Contact with heat and hot substances
0.652 0.347 0.000
X00-X09 Exposure to smoke, fire and flames
0.652 0.347 0.000
W75-W84 Other accidental threats to breathing
0.652 0.347 0.000
W65-W74 Accidental drowning and submersion
0.652 0.347 0.000
V98-V99 Other and unspecified transport accidents
0.652 0.347 0.000
V95-V97 Air and space transport accidents
0.652 0.347 0.000
V90-V94 Water transport accidents
0.652 0.347 0.000
V70-V79 Bus occupant injured in transport accident
0.652 0.347 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.652 0.347 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.652 0.347 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.652 0.347 0.000
V01-V09 Pedestrian injured in transport accident
0.652 0.347 0.000
L40 Psoriasis
0.652 0.348 0.000
I77.8 Other specified disorders of arteries and arterioles
0.000 0.348 0.652
Chapter XVI Certain conditions originating in the perinatal period
0.652 0.348 0.000
S06 Intracranial injury
0.650 0.350 0.000
S71 Open wound of hip and thigh
0.648 0.351 0.000
Y59 Other and unspecified vaccines and biological substances
0.648 0.352 0.000
Y58 Bacterial vaccines
0.648 0.352 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.648 0.352 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.648 0.352 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.648 0.352 0.000
Y48 Anaesthetics and therapeutic gases
0.648 0.352 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.648 0.352 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.648 0.352 0.000
J11 Influenza, virus not identified
0.648 0.352 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.648 0.352 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.647 0.353 0.000
Chapter XXII Codes for special purposes
0.647 0.353 0.000
Q35-Q37 Cleft lip and cleft palate
0.646 0.354 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.646 0.354 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.646 0.354 0.000
I12 Hypertensive renal disease
0.000 0.355 0.645
T95 Sequelae of burns, corrosions and frostbite
0.644 0.356 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.644 0.356 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.644 0.356 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.644 0.356 0.000
Q80-Q89 Other congenital malformations
0.644 0.356 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.356 0.644
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.356 0.644
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.356 0.644
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.356 0.644
I07 Rheumatic tricuspid valve diseases
0.000 0.356 0.644
X20-X29 Contact with venomous animals and plants
0.642 0.357 0.000
S70.1 Contusion of thigh
0.640 0.360 0.000
I78 Diseases of capillaries
0.000 0.361 0.639
S40-S49 Injuries to the shoulder and upper arm
0.639 0.361 0.000
S52.01 Fracture of upper end of ulna (open)
0.638 0.362 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.636 0.364 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.635 0.365 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.634 0.366 0.000
S51 Open wound of forearm
0.633 0.366 0.000
T93 Sequelae of injuries of lower limb
0.633 0.367 0.000
D61.9 Aplastic anaemia, unspecified
0.633 0.367 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.632 0.368 0.000
Q53 Undescended testicle
0.632 0.368 0.000
T98 Sequelae of other and unspecified effects of external causes
0.632 0.368 0.000
I77.0 Arteriovenous fistula, acquired
0.000 0.369 0.631
J33.1 Polypoid sinus degeneration
0.631 0.369 0.000
I27 Other pulmonary heart diseases
0.000 0.369 0.631
H55-H59 Other disorders of eye and adnexa
0.631 0.369 0.000
J38.0 Paralysis of vocal cords and larynx
0.630 0.370 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.371 0.629
Q38 Other congenital malformations of tongue, mouth and pharynx
0.629 0.371 0.000
J38.3 Other diseases of vocal cords
0.628 0.372 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.627 0.373 0.000
H66.3 Other chronic suppurative otitis media
0.627 0.373 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.626 0.374 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.625 0.375 0.000
S52.50 Fracture of lower end of radius (closed)
0.625 0.375 0.000
J37 Chronic laryngitis and laryngotracheitis
0.623 0.376 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.376 0.623
H60-H62 Diseases of external ear
0.622 0.378 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.622 0.378 0.000
J38.4 Oedema of larynx
0.622 0.378 0.000
S52.8 Fracture of other parts of forearm
0.621 0.378 0.000
Y52.1 Calcium-channel blockers
0.622 0.378 0.000
Q54 Hypospadias
0.621 0.378 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.621 0.379 0.000
J33.0 Polyp of nasal cavity
0.619 0.381 0.000
V10-V19 Pedal cyclist injured in transport accident
0.618 0.382 0.000
S72.30 Fracture of shaft of femur (closed)
0.618 0.382 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.618 0.382 0.000
J35 Chronic diseases of tonsils and adenoids
0.617 0.383 0.000
I09 Other rheumatic heart diseases
0.000 0.383 0.616
I06 Rheumatic aortic valve diseases
0.000 0.383 0.616
S52.10 Fracture of upper end of radius (closed)
0.616 0.384 0.000
V20-V29 Motorcycle rider injured in transport accident
0.616 0.384 0.000
I25.5 Ischaemic cardiomyopathy
0.000 0.385 0.615
S22 Fracture of rib(s), sternum and thoracic spine
0.615 0.385 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.614 0.386 0.000
J38.1 Polyp of vocal cord and larynx
0.614 0.386 0.000
Y40.3 Macrolides
0.614 0.386 0.000
T91.8 Sequelae of other specified injuries of neck and trunk
0.613 0.387 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.612 0.387 0.000
J36 Peritonsillar abscess
0.612 0.388 0.000
T20 Burn and corrosion of head and neck
0.612 0.388 0.000
D55-D59 Haemolytic anaemias
0.610 0.390 0.000
D86.8 Sarcoidosis of other and combined sites
0.610 0.390 0.000
Y42.7 Androgens and anabolic congeners
0.610 0.390 0.000
S31 Open wound of abdomen, lower back and pelvis
0.609 0.391 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.609 0.391 0.000
H74 Other disorders of middle ear and mastoid
0.609 0.391 0.000
T40.4 Other synthetic narcotics
0.609 0.391 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.608 0.391 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.608 0.391 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.608 0.391 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.608 0.391 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.608 0.391 0.000
T36 Poisoning by systemic antibiotics
0.608 0.391 0.000
S70.8 Other superficial injuries of hip and thigh
0.608 0.392 0.000
S70.7 Multiple superficial injuries of hip and thigh
0.608 0.392 0.000
Y57.9 Drug or medicament, unspecified
0.608 0.392 0.000
L29.0 Pruritus ani
0.607 0.393 0.000
T39.1 4-Aminophenol derivatives
0.607 0.393 0.000
W94 Exposure to high and low air pressure and changes in air pressure
0.607 0.393 0.000
T78 Adverse effects, not elsewhere classified
0.606 0.394 0.000
H43-H45 Disorders of vitreous body and globe
0.606 0.394 0.000
S81.9 Open wound of lower leg, part unspecified
0.604 0.396 0.000
S89 Other and unspecified injuries of lower leg
0.604 0.396 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.603 0.397 0.000
Q23 Congenital malformations of aortic and mitral valves
0.602 0.398 0.000
S83.2 Tear of meniscus, current
0.602 0.398 0.000
S88 Traumatic amputation of lower leg
0.602 0.398 0.000
S87 Crushing injury of lower leg
0.602 0.398 0.000
S85 Injury of blood vessels at lower leg level
0.602 0.398 0.000
S84 Injury of nerves at lower leg level
0.602 0.398 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.399 0.601
S00.3 Superficial injury of nose
0.601 0.399 0.000
S70.0 Contusion of hip
0.601 0.399 0.000
L40.9 Psoriasis, unspecified
0.601 0.399 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.601 0.399 0.000
Q55 Other congenital malformations of male genital organs
0.601 0.399 0.000
Q52 Other congenital malformations of female genitalia
0.601 0.399 0.000
S72.4 Fracture of lower end of femur
0.600 0.399 0.000
T90 Sequelae of injuries of head
0.600 0.400 0.000
I71.0 Dissection of aorta [any part]
0.000 0.402 0.598
J60-J70 Lung diseases due to external agents
0.598 0.402 0.000
L30 Other dermatitis
0.597 0.403 0.000
S72.01 Fracture of neck of femur (open)
0.597 0.403 0.000
Q61 Cystic kidney disease
0.597 0.403 0.000
V48 Car occupant injured in noncollision transport accident
0.596 0.404 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.596 0.404 0.000
H69 Other disorders of Eustachian tube
0.596 0.404 0.000
T91.1 Sequelae of fracture of spine
0.596 0.404 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.594 0.406 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.594 0.406 0.000
T92.4 Sequelae of injury of nerve of upper limb
0.594 0.406 0.000
T92.0 Sequelae of open wound of upper limb
0.594 0.406 0.000
Y54.5 Other diuretics
0.594 0.406 0.000
S00.5 Superficial injury of lip and oral cavity
0.593 0.407 0.000
T70.3 Caisson disease [decompression sickness]
0.591 0.409 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.590 0.410 0.000
D84 Other immunodeficiencies
0.590 0.410 0.000
I70.9 Generalised and unspecified atherosclerosis
0.000 0.410 0.590
I70.8 Atherosclerosis of other arteries
0.000 0.410 0.590
I70.1 Atherosclerosis of renal artery
0.000 0.410 0.590
I70.0 Atherosclerosis of aorta
0.000 0.410 0.590
S59.9 Unspecified injury of forearm
0.589 0.411 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.589 0.411 0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified
0.588 0.412 0.000
T39.0 Salicylates
0.588 0.412 0.000
W19.9 Unspecified place
0.588 0.412 0.000
H33.4 Traction detachment of retina
0.588 0.412 0.000
T51 Toxic effect of alcohol
0.587 0.413 0.000
H33.2 Serous retinal detachment
0.587 0.413 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.586 0.414 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.414 0.586
I12.0 Hypertensive renal disease with renal failure
0.000 0.415 0.585
Y40.9 Systemic antibiotic, unspecified
0.585 0.415 0.000
S64 Injury of nerves at wrist and hand level
0.585 0.415 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.584 0.415 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.584 0.416 0.000
Q18 Other congenital malformations of face and neck
0.582 0.418 0.000
S08 Traumatic amputation of part of head
0.581 0.418 0.000
S07 Crushing injury of head
0.581 0.418 0.000
S04 Injury of cranial nerves
0.581 0.418 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.581 0.418 0.000
T75 Effects of other external causes
0.580 0.420 0.000
T74 Maltreatment syndromes
0.580 0.420 0.000
T73 Effects of other deprivation
0.580 0.420 0.000
T69 Other effects of reduced temperature
0.580 0.420 0.000
T67 Effects of heat and light
0.580 0.420 0.000
T71 Asphyxiation
0.580 0.420 0.000
T66 Unspecified effects of radiation
0.580 0.420 0.000
S86 Injury of muscle and tendon at lower leg level
0.579 0.420 0.000
Q43 Other congenital malformations of intestine
0.579 0.421 0.000
I74.5 Embolism and thrombosis of iliac artery
0.000 0.422 0.578
S73.0 Dislocation of hip
0.578 0.422 0.000
Y40.7 Antifungal antibiotics, systemically used
0.577 0.423 0.000
Y40.6 Rifamycins
0.577 0.423 0.000
Y40.5 Aminoglycosides
0.577 0.423 0.000
Y40.4 Tetracyclines
0.577 0.423 0.000
Y40.2 Chloramphenicol group
0.577 0.423 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.577 0.423 0.000
T68 Hypothermia
0.577 0.423 0.000
T09 Other injuries of spine and trunk, level unspecified
0.576 0.423 0.000
H73 Other disorders of tympanic membrane
0.576 0.424 0.000
J21 Acute bronchiolitis
0.576 0.424 0.000
J20 Acute bronchitis
0.576 0.424 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.575 0.424 0.000
H70 Mastoiditis and related conditions
0.575 0.424 0.000
H68 Eustachian salpingitis and obstruction
0.575 0.424 0.000
H67 Otitis media in diseases classified elsewhere
0.575 0.424 0.000
J17 Pneumonia in diseases classified elsewhere
0.575 0.424 0.000
T40.2 Other opioids
0.575 0.425 0.000
X45 Accidental poisoning by and exposure to alcohol
0.575 0.425 0.000
I08.9 Multiple valve disease, unspecified
0.000 0.426 0.574
I08.8 Other multiple valve diseases
0.000 0.426 0.574
L42 Pityriasis rosea
0.574 0.426 0.000
T25 Burn and corrosion of ankle and foot
0.573 0.426 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.573 0.426 0.000
T21 Burn and corrosion of trunk
0.573 0.426 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.574 0.426 0.000
Q28 Other congenital malformations of circulatory system
0.573 0.426 0.000
T23 Burn and corrosion of wrist and hand
0.573 0.427 0.000
S11 Open wound of neck
0.571 0.429 0.000
H40 Glaucoma
0.570 0.430 0.000
H33.1 Retinoschisis and retinal cysts
0.569 0.431 0.000
Y57.8 Other drugs and medicaments
0.569 0.431 0.000
Y57.7 Vitamins, not elsewhere classified
0.569 0.431 0.000
Y57.6 Other diagnostic agents
0.569 0.431 0.000
Y57.4 Pharmaceutical excipients
0.569 0.431 0.000
Y57.3 Alcohol deterrents
0.569 0.431 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.569 0.431 0.000
Y57.1 Lipotropic drugs
0.569 0.431 0.000
Y57.0 Appetite depressants [anorectics]
0.569 0.431 0.000
J31.0 Chronic rhinitis
0.569 0.431 0.000
S05 Injury of eye and orbit
0.569 0.431 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.431 0.568
L29.8 Other pruritus
0.568 0.432 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.568 0.432 0.000
S72.11 Pertrochanteric fracture (open)
0.565 0.435 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.565 0.435 0.000
S60 Superficial injury of wrist and hand
0.565 0.435 0.000
S72.20 Subtrochanteric fracture (closed)
0.565 0.435 0.000
Y49.2 Other and unspecified antidepressants
0.564 0.435 0.000
T91.3 Sequelae of injury of spinal cord
0.564 0.436 0.000
S27 Injury of other and unspecified intrathoracic organs
0.563 0.437 0.000
S00.4 Superficial injury of ear
0.563 0.437 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.563 0.437 0.000
X50 Overexertion and strenuous or repetitive movements
0.563 0.437 0.000
S62 Fracture at wrist and hand level
0.561 0.439 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.561 0.439 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.560 0.439 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.560 0.439 0.000
Y52.7 Peripheral vasodilators
0.560 0.439 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.560 0.439 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.560 0.439 0.000
J38.6 Stenosis of larynx
0.560 0.440 0.000
S02 Fracture of skull and facial bones
0.560 0.440 0.000
W20-W49 Exposure to inanimate mechanical forces
0.560 0.440 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.559 0.440 0.000
W55 Bitten or struck by other mammals
0.559 0.441 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.559 0.441 0.000
Y44.7 Plasma substitutes
0.559 0.441 0.000
Y44.6 Natural blood and blood products
0.559 0.441 0.000
Y44.5 Thrombolytic drugs
0.559 0.441 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.559 0.441 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.559 0.441 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.559 0.441 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.559 0.441 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.558 0.442 0.000
Y54.3 Benzothiadiazine derivatives
0.557 0.443 0.000
H66.4 Suppurative otitis media, unspecified
0.557 0.443 0.000
H66.2 Chronic atticoantral suppurative otitis media
0.557 0.443 0.000
H66.1 Chronic tubotympanic suppurative otitis media
0.557 0.443 0.000
H66.0 Acute suppurative otitis media
0.557 0.443 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.557 0.443 0.000
J12 Viral pneumonia, not elsewhere classified
0.557 0.443 0.000
J14 Pneumonia due to Haemophilus influenzae
0.557 0.443 0.000
J09 Influenza due to certain identified influenza virus
0.557 0.443 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.557 0.443 0.000
H31 Other disorders of choroid
0.556 0.444 0.000
H80-H83 Diseases of inner ear
0.556 0.444 0.000
L40.5 Arthropathic psoriasis
0.556 0.444 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.556 0.444 0.000
W13 Fall from, out of or through building or structure
0.555 0.445 0.000
L27 Dermatitis due to substances taken internally
0.555 0.445 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.446 0.554
I74.8 Embolism and thrombosis of other arteries
0.000 0.446 0.554
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.446 0.554
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.446 0.554
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.446 0.554
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.446 0.554
Q45 Other congenital malformations of digestive system
0.554 0.446 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.554 0.446 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.554 0.446 0.000
Q40 Other congenital malformations of upper alimentary tract
0.554 0.446 0.000
Q39 Congenital malformations of oesophagus
0.554 0.446 0.000
D62 Acute posthaemorrhagic anaemia
0.553 0.447 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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