TreeWAS – Variant ID: rs55961051

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
Chapter X Diseases of the respiratory system	0.994	0.006
Chapter XX External causes of morbidity and mortality	0.989	0.011
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.984	0.016
Chapter XIV Diseases of the genitourinary system	0.983	0.017
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.980	0.020
Chapter II Neoplasms	0.976	0.024
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.971	0.029
N17-N19 Renal failure	0.970	0.030
J30-J39 Other diseases of upper respiratory tract	0.961	0.039
N18 Chronic renal failure	0.956	0.044
T81 Complications of procedures, not elsewhere classified	0.951	0.049
Chapter XII Diseases of the skin and subcutaneous tissue	0.943	0.057
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.929	0.071
S60-S69 Injuries to the wrist and hand	0.928	0.072
Chapter VIII Diseases of the ear and mastoid process	0.926	0.074
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.926	0.074
N80-N98 Noninflammatory disorders of female genital tract	0.925	0.075
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.922	0.078
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.915	0.085
N18.9 Chronic renal failure, unspecified	0.914	0.086
N92 Excessive, frequent and irregular menstruation	0.904	0.096
C51-C58 Malignant neoplasms of female genital organs	0.895	0.105
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.895	0.105
M70-M79 Other soft tissue disorders	0.881	0.119
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.877	0.123
N92.0 Excessive and frequent menstruation with regular cycle	0.872	0.128
S61 Open wound of wrist and hand	0.872	0.128
T66-T78 Other and unspecified effects of external causes	0.870	0.130
R91 Abnormal findings on diagnostic imaging of lung	0.870	0.130
Chapter IX Diseases of the circulatory system	0.867	0.133
T81.4 Infection following a procedure, not elsewhere classified	0.863	0.137
N81 Female genital prolapse	0.859	0.141
W20-W49 Exposure to inanimate mechanical forces	0.857	0.143
J32 Chronic sinusitis	0.857	0.143
H65-H75 Diseases of middle ear and mastoid	0.855	0.145
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.853	0.147
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.852	0.148
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.849	0.151
N18.3 Chronic kidney disease, stage 3	0.848	0.152
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.848	0.152
J20-J22 Other acute lower respiratory infections	0.846	0.154
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.846	0.154
T36-T50 Poisoning by drugs, medicaments and biological substances	0.844	0.156
M79 Other soft tissue disorders, not elsewhere classified	0.844	0.156
D60-D64 Aplastic and other anaemias	0.840	0.160
D10-D36 Benign neoplasms	0.839	0.161
N70-N77 Inflammatory diseases of female pelvic organs	0.838	0.162
N92.1 Excessive and frequent menstruation with irregular cycle	0.834	0.166
Chapter V Mental and behavioural disorders	0.831	0.169
J40-J47 Chronic lower respiratory diseases	0.831	0.169
M50-M54 Other dorsopathies	0.825	0.175
M45-M49 Spondylopathies	0.823	0.177
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.819	0.181
R93 Abnormal findings on diagnostic imaging of other body structures	0.812	0.188
S80-S89 Injuries to the knee and lower leg	0.811	0.189
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.808	0.192
S61.0 Open wound of finger(s) without damage to nail	0.808	0.192
M79.6 Pain in limb	0.808	0.192
N10-N16 Renal tubulo-interstitial diseases	0.802	0.198
J80-J84 Other respiratory diseases principally affecting the interstitium	0.799	0.201
Y83.1 Surgical operation with implant of artificial internal device	0.799	0.201
N18.5 Chronic kidney disease, stage 5	0.799	0.201
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.795	0.205
J33 Nasal polyp	0.787	0.213
J95-J99 Other diseases of the respiratory system	0.784	0.216
J32.9 Chronic sinusitis, unspecified	0.782	0.218
L80-L99 Other disorders of the skin and subcutaneous tissue	0.779	0.221
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.779	0.221
J90-J94 Other diseases of pleura	0.779	0.221
T78 Adverse effects, not elsewhere classified	0.778	0.222
L50-L54 Urticaria and erythema	0.777	0.223
C56 Malignant neoplasm of ovary	0.775	0.225
C54 Malignant neoplasm of corpus uteri	0.773	0.227
F30-F39 Mood [affective] disorders	0.771	0.229
S70-S79 Injuries to the hip and thigh	0.771	0.229
D25 Leiomyoma of uterus	0.766	0.234
I30-I52 Other forms of heart disease	0.764	0.236
N87 Dysplasia of cervix uteri	0.764	0.236
Y43 Primarily systemic agents	0.763	0.237
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.762	0.238
L60-L75 Disorders of skin appendages	0.762	0.238
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.760	0.240
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.760	0.240
T79-T79 Certain early complications of trauma	0.759	0.240
C15-C26 Malignant neoplasms of digestive organs	0.759	0.241
D70-D77 Other diseases of blood and blood-forming organs	0.759	0.241
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.758	0.241
N17 Acute renal failure	0.756	0.244
Chapter XXII Codes for special purposes	0.755	0.245
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.753	0.247
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.750	0.250
C43-C44 Melanoma and other malignant neoplasms of skin	0.750	0.250
Y86 Sequelae of other accidents	0.749	0.251
L40-L45 Papulosquamous disorders	0.748	0.252
J09-J18 Influenza and pneumonia	0.747	0.253
D18 Haemangioma and lymphangioma, any site	0.747	0.253
J30 Vasomotor and allergic rhinitis	0.743	0.257
W29 Contact with other powered hand tools and household machinery	0.742	0.258
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.741	0.259
D62 Acute posthaemorrhagic anaemia	0.741	0.259
S20-S29 Injuries to the thorax	0.741	0.259
S90-S99 Injuries to the ankle and foot	0.740	0.260
J22 Unspecified acute lower respiratory infection	0.739	0.261
R47-R49 Symptoms and signs involving speech and voice	0.739	0.261
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.739	0.261
S50-S59 Injuries to the elbow and forearm	0.735	0.265
H60-H62 Diseases of external ear	0.734	0.266
M80-M85 Disorders of bone density and structure	0.734	0.266
I05-I09 Chronic rheumatic heart diseases	0.733	0.267
J44 Other chronic obstructive pulmonary disease	0.733	0.267
Y60-Y69 Misadventures to patients during surgical and medical care	0.731	0.269
N60-N64 Disorders of breast	0.730	0.270
I20-I25 Ischaemic heart diseases	0.729	0.271
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.728	0.272
N81.5 Vaginal enterocele	0.726	0.274
R06 Abnormalities of breathing	0.725	0.275
F32 Depressive episode	0.724	0.276
N00-N08 Glomerular diseases	0.723	0.277
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.721	0.279
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
N19 Unspecified renal failure	0.717	0.283
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T15-T19 Effects of foreign body entering through natural orifice	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
S10-S19 Injuries to the neck	0.716	0.284
R42 Dizziness and giddiness	0.713	0.287
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.713	0.287
J60-J70 Lung diseases due to external agents	0.713	0.287
T78.4 Allergy, unspecified	0.712	0.287
T85 Complications of other internal prosthetic devices, implants and grafts	0.711	0.289
R45 Symptoms and signs involving emotional state	0.711	0.289
H65 Nonsuppurative otitis media	0.710	0.290
M79.69 Pain in limb (Site unspecified)	0.709	0.290
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.709	0.291
C90 Multiple myeloma and malignant plasma cell neoplasms	0.709	0.291
I70-I79 Diseases of arteries, arterioles and capillaries	0.709	0.291
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.709	0.291
Y35-Y36 Legal intervention and operations of war	0.709	0.291
Y10-Y34 Event of undetermined intent	0.709	0.291
Y00-Y09 Assault	0.709	0.291
X85-X99 Assault	0.709	0.291
X60-X84 Intentional self-harm	0.709	0.291
X58-X59 Accidental exposure to other and unspecified factors	0.709	0.291
X50-X57 Overexertion, travel and privation	0.709	0.291
X40-X49 Accidental poisoning by and exposure to noxious substances	0.709	0.291
X30-X39 Exposure to forces of nature	0.709	0.291
X20-X29 Contact with venomous animals and plants	0.709	0.291
X10-X19 Contact with heat and hot substances	0.709	0.291
X00-X09 Exposure to smoke, fire and flames	0.709	0.291
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.709	0.291
W75-W84 Other accidental threats to breathing	0.709	0.291
W65-W74 Accidental drowning and submersion	0.709	0.291
W50-W64 Exposure to animate mechanical forces	0.709	0.291
V98-V99 Other and unspecified transport accidents	0.709	0.291
V95-V97 Air and space transport accidents	0.709	0.291
V90-V94 Water transport accidents	0.709	0.291
V80-V89 Other land transport accidents	0.709	0.291
V70-V79 Bus occupant injured in transport accident	0.709	0.291
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.709	0.291
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.709	0.291
V40-V49 Car occupant injured in transport accident	0.709	0.291
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.709	0.291
V20-V29 Motorcycle rider injured in transport accident	0.709	0.291
V10-V19 Pedal cyclist injured in transport accident	0.709	0.291
V01-V09 Pedestrian injured in transport accident	0.709	0.291
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.708	0.292
R26 Abnormalities of gait and mobility	0.708	0.292
H72 Perforation of tympanic membrane	0.708	0.292
N81.4 Uterovaginal prolapse, unspecified	0.708	0.292
M65-M68 Disorders of synovium and tendon	0.707	0.292
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.707	0.293
R95-R99 Ill-defined and unknown causes of mortality	0.705	0.295
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.705	0.295
M79.8 Other specified soft tissue disorders	0.705	0.295
L20-L30 Dermatitis and eczema	0.704	0.296
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.704	0.296
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.703	0.297
T88 Other complications of surgical and medical care, not elsewhere classified	0.703	0.297
T87 Complications peculiar to reattachment and amputation	0.703	0.297
T86 Failure and rejection of transplanted organs and tissues	0.703	0.297
T80 Complications following infusion, transfusion and therapeutic injection	0.703	0.297
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.702	0.298
R44 Other symptoms and signs involving general sensations and perceptions	0.702	0.298
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.700	0.300
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.700	0.300
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.700	0.300
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.700	0.300
C40-C41 Malignant neoplasms of bone and articular cartilage	0.700	0.300
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.700	0.300
M15-M19 Arthrosis	0.699	0.301
M40-M43 Deforming dorsopathies	0.698	0.302
H66 Suppurative and unspecified otitis media	0.698	0.302
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.698	0.302
J38.7 Other diseases of larynx	0.697	0.303
L00-L08 Infections of the skin and subcutaneous tissue	0.697	0.303
N99-N99 Other disorders of the genitourinary system	0.697	0.303
R25 Abnormal involuntary movements	0.696	0.304
M91-M94 Chondropathies	0.696	0.304
M86-M90 Other osteopathies	0.696	0.304
M60-M63 Disorders of muscles	0.696	0.304
M00-M03 Infectious arthropathies	0.696	0.304
M20-M25 Other joint disorders	0.696	0.304
L97 Ulcer of lower limb, not elsewhere classified	0.695	0.305
N92.4 Excessive bleeding in the premenopausal period	0.694	0.306
S66 Injury of muscle and tendon at wrist and hand level	0.693	0.307
Chapter I Certain infectious and parasitic diseases	0.691	0.309
F32.9 Depressive episode, unspecified	0.690	0.310
N81.8 Other female genital prolapse	0.690	0.310
J39 Other diseases of upper respiratory tract	0.689	0.311
J37 Chronic laryngitis and laryngotracheitis	0.689	0.311
J36 Peritonsillar abscess	0.689	0.311
I95-I99 Other and unspecified disorders of the circulatory system	0.688	0.312
S64 Injury of nerves at wrist and hand level	0.687	0.313
C54.1 Endometrium	0.686	0.314
N18.8 Other chronic renal failure	0.685	0.314
N18.4 Chronic kidney disease, stage 4	0.685	0.314
N18.2 Chronic kidney disease, stage 2	0.685	0.314
N18.1 Chronic kidney disease, stage 1	0.685	0.314
N18.0 End-stage renal disease	0.685	0.314
D25.9 Leiomyoma of uterus, unspecified	0.685	0.315
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.685	0.315
I50 Heart failure	0.684	0.316
C50-C50 Malignant neoplasm of breast	0.684	0.316
J43 Emphysema	0.684	0.316
J38.1 Polyp of vocal cord and larynx	0.684	0.316
M47 Spondylosis	0.684	0.316
C80 Malignant neoplasm without specification of site	0.683	0.316
D22 Melanocytic naevi	0.682	0.318
T81.9 Unspecified complication of procedure	0.682	0.318
T81.7 Vascular complications following a procedure, not elsewhere classified	0.682	0.318
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.682	0.318
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.682	0.318
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.682	0.318
D18.0 Haemangioma, any site	0.682	0.318
J38.3 Other diseases of vocal cords	0.681	0.319
M79.67 Pain in limb (Ankle and foot)	0.681	0.319
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.680	0.320
D80-D89 Certain disorders involving the immune mechanism	0.678	0.322
R40 Somnolence, stupor and coma	0.678	0.322
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.678	0.322
Y51 Drugs primarily affecting the autonomic nervous system	0.677	0.323
F00-F09 Organic, including symptomatic, mental disorders	0.676	0.324
S61.8 Open wound of other parts of wrist and hand	0.676	0.324
S82 Fracture of lower leg, including ankle	0.676	0.324
L10-L14 Bullous disorders	0.676	0.324
J00-J06 Acute upper respiratory infections	0.676	0.324
S68 Traumatic amputation of wrist and hand	0.674	0.326
D00-D09 In situ neoplasms	0.674	0.326
N73 Other female pelvic inflammatory diseases	0.673	0.327
J35 Chronic diseases of tonsils and adenoids	0.672	0.327
S61.1 Open wound of finger(s) with damage to nail	0.672	0.328
W00-W19 Falls	0.671	0.329
N75 Diseases of Bartholin's gland	0.671	0.329
H90-H95 Other disorders of ear	0.671	0.329
M50 Cervical disk disorders	0.670	0.330
D36 Benign neoplasm of other and unspecified sites	0.670	0.330
N81.3 Complete uterovaginal prolapse	0.670	0.330
N85 Other noninflammatory disorders of uterus, except cervix	0.670	0.330
Y43.3 Other antineoplastic drugs	0.669	0.331
C79 Secondary malignant neoplasm of other sites	0.668	0.332
S40-S49 Injuries to the shoulder and upper arm	0.667	0.333
M54 Dorsalgia	0.666	0.334
D55-D59 Haemolytic anaemias	0.666	0.334
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.666	0.334
S69 Other and unspecified injuries of wrist and hand	0.666	0.334
S67 Crushing injury of wrist and hand	0.666	0.334
S65 Injury of blood vessels at wrist and hand level	0.666	0.334
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.666	0.334
S60 Superficial injury of wrist and hand	0.666	0.334
D37-D48 Neoplasms of uncertain or unknown behaviour	0.665	0.334
C83 Diffuse non-Hodgkin's lymphoma	0.665	0.335
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.664	0.336
R90 Abnormal findings on diagnostic imaging of central nervous system	0.664	0.336
R92 Abnormal findings on diagnostic imaging of breast	0.664	0.336
N98 Complications associated with artificial fertilisation	0.663	0.337
N91 Absent, scanty and rare menstruation	0.663	0.337
N82 Fistulae involving female genital tract	0.663	0.337
N96 Habitual aborter	0.663	0.337
W29.9 Unspecified place	0.660	0.340
J84 Other interstitial pulmonary diseases	0.660	0.340
R18 Ascites	0.659	0.341
W25 Contact with sharp glass	0.659	0.341
D35 Benign neoplasm of other and unspecified endocrine glands	0.659	0.341
N25-N29 Other disorders of kidney and ureter	0.658	0.342
M79.62 Pain in limb (Upper arm)	0.657	0.343
D61 Other aplastic anaemias	0.657	0.343
C16 Malignant neoplasm of stomach	0.656	0.344
Y83.6 Removal of other organ (partial) (total)	0.655	0.345
H80-H83 Diseases of inner ear	0.652	0.348
R04 Haemorrhage from respiratory passages	0.652	0.348
C43 Malignant melanoma of skin	0.652	0.348
N81.6 Rectocele	0.650	0.350
N92.5 Other specified irregular menstruation	0.648	0.351
N92.2 Excessive menstruation at puberty	0.648	0.351
R13 Dysphagia	0.647	0.353
R06.0 Dyspnoea	0.647	0.353
T84.0 Mechanical complication of internal joint prosthesis	0.645	0.355
D64 Other anaemias	0.644	0.356
M46 Other inflammatory spondylopathies	0.643	0.357
N90 Other noninflammatory disorders of vulva and perineum	0.643	0.357
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.643	0.357
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.642	0.358
C57 Malignant neoplasm of other and unspecified female genital organs	0.642	0.358
C53 Malignant neoplasm of cervix uteri	0.642	0.358
C51 Malignant neoplasm of vulva	0.642	0.358
C58 Malignant neoplasm of placenta	0.642	0.358
C55 Malignant neoplasm of uterus, part unspecified	0.642	0.358
C52 Malignant neoplasm of vagina	0.642	0.358
Y59 Other and unspecified vaccines and biological substances	0.642	0.358
Y58 Bacterial vaccines	0.642	0.358
Y57 Other and unspecified drugs and medicaments	0.642	0.358
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.642	0.358
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.642	0.358
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.642	0.358
Y53 Agents primarily affecting the gastro-intestinal system	0.642	0.358
Y52 Agents primarily affecting the cardiovascular system	0.642	0.358
Y50 Central nervous system stimulants, not elsewhere classified	0.642	0.358
Y49 Psychotropic drugs, not elsewhere classified	0.642	0.358
Y48 Anaesthetics and therapeutic gases	0.642	0.358
Y47 Sedatives, hypnotics and antianxiety drugs	0.642	0.358
Y46 Antiepileptics and anti-Parkinsonism drugs	0.642	0.358
Y44 Agents primarily affecting blood constituents	0.642	0.358
Y41 Other systemic anti-infectives and antiparasitics	0.642	0.358
Y40 Systemic antibiotics	0.642	0.358
H71 Cholesteatoma of middle ear	0.641	0.359
R02 Gangrene, not elsewhere classified	0.640	0.360
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.640	0.360
I08 Multiple valve diseases	0.638	0.362
J90 Pleural effusion, not elsewhere classified	0.637	0.363
L50 Urticaria	0.636	0.364
T83.0 Mechanical complication of urinary (indwelling) catheter	0.635	0.365
D33 Benign neoplasm of brain and other parts of central nervous system	0.634	0.366
S62 Fracture at wrist and hand level	0.633	0.367
M77 Other enthesopathies	0.631	0.369
M76 Enthesopathies of lower limb, excluding foot	0.631	0.369
M73 Soft tissue disorders in diseases classified elsewhere	0.631	0.369
M71 Other bursopathies	0.631	0.369
M70 Soft tissue disorders related to use, overuse and pressure	0.631	0.369
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.631	0.369
D17 Benign lipomatous neoplasm	0.630	0.370
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.630	0.370
J33.9 Nasal polyp, unspecified	0.629	0.371
R46 Symptoms and signs involving appearance and behaviour	0.628	0.371
R43 Disturbances of smell and taste	0.628	0.371
I38 Endocarditis, valve unspecified	0.628	0.372
S61.9 Open wound of wrist and hand, part unspecified	0.628	0.372
N72 Inflammatory disease of cervix uteri	0.627	0.373
N88 Other noninflammatory disorders of cervix uteri	0.626	0.374
S61.7 Multiple open wounds of wrist and hand	0.625	0.375
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.625	0.375
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.625	0.375
L91 Hypertrophic disorders of skin	0.625	0.375
N81.1 Cystocele	0.625	0.375
T75 Effects of other external causes	0.624	0.376
T74 Maltreatment syndromes	0.624	0.376
T73 Effects of other deprivation	0.624	0.376
T70 Effects of air pressure and water pressure	0.624	0.376
T69 Other effects of reduced temperature	0.624	0.376
T67 Effects of heat and light	0.624	0.376
T71 Asphyxiation	0.624	0.376
T68 Hypothermia	0.624	0.376
T66 Unspecified effects of radiation	0.624	0.376
I20 Angina pectoris	0.623	0.377
J47 Bronchiectasis	0.623	0.377
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.622	0.378
C64-C68 Malignant neoplasms of urinary tract	0.622	0.378
I35 Nonrheumatic aortic valve disorders	0.622	0.378
I00-I02 Acute rheumatic fever	0.622	0.378
Y83.8 Other surgical procedures	0.622	0.378
M79.60 Pain in limb (Multiple sites)	0.621	0.379
D50-D53 Nutritional anaemias	0.621	0.379
N87.0 Mild cervical dysplasia	0.618	0.382
R06.8 Other and unspecified abnormalities of breathing	0.618	0.382
Y83.3 Surgical operation with formation of external stoma	0.616	0.384
N81.9 Female genital prolapse, unspecified	0.616	0.384
N81.0 Female urethrocele	0.616	0.384
N84 Polyp of female genital tract	0.615	0.385
M05-M14 Inflammatory polyarthropathies	0.615	0.385
Y84.6 Urinary catheterisation	0.615	0.385
W49 Exposure to other and unspecified inanimate mechanical forces	0.615	0.385
W46 Contact with hypodermic needle	0.615	0.385
W45 Foreign body or object entering through skin	0.615	0.385
W44 Foreign body entering into or through eye or natural orifice	0.615	0.385
W43 Exposure to vibration	0.615	0.385
W42 Exposure to noise	0.615	0.385
W41 Exposure to high-pressure jet	0.615	0.385
W40 Explosion of other materials	0.615	0.385
W39 Discharge of firework	0.615	0.385
W38 Explosion and rupture of other specified pressurised devices	0.615	0.385
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.615	0.385
W36 Explosion and rupture of gas cylinder	0.615	0.385
W35 Explosion and rupture of boiler	0.615	0.385
W34 Discharge from other and unspecified firearms	0.615	0.385
W33 Rifle, shotgun and larger firearm discharge	0.615	0.385
W32 Handgun discharge	0.615	0.385
W31 Contact with other and unspecified machinery	0.615	0.385
W30 Contact with agricultural machinery	0.615	0.385
W28 Contact with powered lawn mower	0.615	0.385
W27 Contact with nonpowered hand tool	0.615	0.385
W26 Contact with knife, sword or dagger	0.615	0.385
W24 Contact with lifting and transmission devices, not elsewhere classified	0.615	0.385
W23 Caught, crushed, jammed or pinched in or between objects	0.615	0.385
W22 Striking against or struck by other objects	0.615	0.385
W21 Striking against or struck by sports equipment	0.615	0.385
W20 Struck by thrown, projected or falling object	0.615	0.385
D25.1 Intramural leiomyoma of uterus	0.614	0.385
L40 Psoriasis	0.614	0.386
J32.8 Other chronic sinusitis	0.614	0.386
J32.4 Chronic pansinusitis	0.614	0.386
J32.3 Chronic sphenoidal sinusitis	0.614	0.386
J32.2 Chronic ethmoidal sinusitis	0.614	0.386
J32.1 Chronic frontal sinusitis	0.614	0.386
J32.0 Chronic maxillary sinusitis	0.614	0.386
J31.0 Chronic rhinitis	0.613	0.387
I50.1 Left ventricular failure	0.613	0.387
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.613	0.387
H74 Other disorders of middle ear and mastoid	0.613	0.387
H73 Other disorders of tympanic membrane	0.613	0.387
H70 Mastoiditis and related conditions	0.613	0.387
H69 Other disorders of Eustachian tube	0.613	0.387
H68 Eustachian salpingitis and obstruction	0.613	0.387
H67 Otitis media in diseases classified elsewhere	0.613	0.387
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.613	0.387
J38.6 Stenosis of larynx	0.611	0.388
J38.5 Laryngeal spasm	0.611	0.388
J38.4 Oedema of larynx	0.611	0.388
J38.2 Nodules of vocal cords	0.611	0.388
J38.0 Paralysis of vocal cords and larynx	0.611	0.388
J33.0 Polyp of nasal cavity	0.611	0.388
C90.0 Multiple myeloma	0.611	0.389
R27 Other lack of coordination	0.611	0.389
L85 Other epidermal thickening	0.611	0.389
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.610	0.390
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.610	0.390
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.609	0.390
L81 Other disorders of pigmentation	0.609	0.391
Y89 Sequelae of other external causes	0.609	0.391
Y88 Sequelae of surgical and medical care as external cause	0.609	0.391
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.609	0.391
Y85 Sequelae of transport accidents	0.609	0.391
Y83.9 Surgical procedure, unspecified	0.608	0.392
Y83.5 Amputation of limb(s)	0.608	0.392
Y83.0 Surgical operation with transplant of whole organ	0.608	0.392
C18 Malignant neoplasm of colon	0.608	0.392
R50-R69 General symptoms and signs	0.607	0.393
S72 Fracture of femur	0.607	0.393
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.607	0.393
J21 Acute bronchiolitis	0.606	0.393
J20 Acute bronchitis	0.606	0.393
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.606	0.394
C95 Leukaemia of unspecified cell type	0.606	0.394
C94 Other leukaemias of specified cell type	0.606	0.394
C93 Monocytic leukaemia	0.606	0.394
C92 Myeloid leukaemia	0.606	0.394
C91 Lymphoid leukaemia	0.606	0.394
C88 Malignant immunoproliferative diseases	0.606	0.394
C86 Other specified types of T/NK-cell lymphoma	0.606	0.394
C84 Peripheral and cutaneous T-cell lymphomas	0.606	0.394
C81 Hodgkin's disease	0.606	0.394
M16 Coxarthrosis [arthrosis of hip]	0.606	0.394
R20 Disturbances of skin sensation	0.606	0.394
H65.3 Chronic mucoid otitis media	0.606	0.394
M79.65 Pain in limb (Pelvic region and thigh)	0.606	0.394
R72 Abnormality of white blood cells, not elsewhere classified	0.606	0.394
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.605	0.395
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.605	0.395
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.605	0.395
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.605	0.395
T46 Poisoning by agents primarily affecting the cardiovascular system	0.605	0.395
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.605	0.395
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.605	0.395
T41 Poisoning by anaesthetics and therapeutic gases	0.605	0.395
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.605	0.395
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.605	0.395
T36 Poisoning by systemic antibiotics	0.605	0.395
M79.9 Soft tissue disorder, unspecified	0.605	0.395
M79.7 Fibromyalgia	0.605	0.395
M79.5 Residual foreign body in soft tissue	0.605	0.395
M79.4 Hypertrophy of (infrapatellar) fat pad	0.605	0.395
M79.3 Panniculitis, unspecified	0.605	0.395
M79.2 Neuralgia and neuritis, unspecified	0.605	0.395
M79.1 Myalgia	0.605	0.395
R05 Cough	0.605	0.395
C34 Malignant neoplasm of bronchus and lung	0.605	0.395
M79.86 Other specified soft tissue disorders (Lower leg)	0.605	0.395
R26.8 Other and unspecified abnormalities of gait and mobility	0.604	0.396
D75 Other diseases of blood and blood-forming organs	0.604	0.396
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.603	0.396
J98 Other respiratory disorders	0.603	0.397
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.602	0.397
L60 Nail disorders	0.602	0.398
H72.9 Perforation of tympanic membrane, unspecified	0.602	0.398
N17.9 Acute renal failure, unspecified	0.602	0.398

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations