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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs58280396
log Bayes Factor = 16.5379
Chromosome 18   position 55,720,852  (GRCh37) Explore rs58280396 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.996 0.004 0.000
K55-K64 Other diseases of intestines
0.996 0.004 0.000
M15-M19 Arthrosis
0.992 0.008 0.000
Chapter IX Diseases of the circulatory system
0.990 0.010 0.000
Chapter XIV Diseases of the genitourinary system
0.983 0.017 0.000
N17-N19 Renal failure
0.979 0.021 0.000
N18 Chronic renal failure
0.978 0.022 0.000
A00-A09 Intestinal infectious diseases
0.977 0.023 0.000
I30-I52 Other forms of heart disease
0.975 0.025 0.000
G20-G26 Extrapyramidal and movement disorders
0.973 0.027 0.000
M45-M49 Spondylopathies
0.972 0.028 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.967 0.033 0.000
D50-D53 Nutritional anaemias
0.966 0.034 0.000
Chapter X Diseases of the respiratory system
0.965 0.035 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.961 0.039 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.959 0.041 0.000
N18.9 Chronic renal failure, unspecified
0.959 0.041 0.000
D60-D64 Aplastic and other anaemias
0.957 0.043 0.000
G20 Parkinson's disease
0.953 0.047 0.000
M19 Other arthrosis
0.952 0.048 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.949 0.051 0.000
K57 Diverticular disease of intestine
0.946 0.054 0.000
K70-K77 Diseases of liver
0.941 0.059 0.000
I60-I69 Cerebrovascular diseases
0.939 0.061 0.000
G40-G47 Episodic and paroxysmal disorders
0.936 0.064 0.000
K63 Other diseases of intestine
0.933 0.067 0.000
N18.3 Chronic kidney disease, stage 3
0.933 0.067 0.000
D50 Iron deficiency anaemia
0.931 0.069 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.931 0.069 0.000
D64 Other anaemias
0.927 0.073 0.000
Chapter XX External causes of morbidity and mortality
0.927 0.073 0.000
M19.9 Arthrosis, unspecified
0.923 0.077 0.000
M20-M25 Other joint disorders
0.921 0.079 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.920 0.080 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.918 0.082 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.909 0.091 0.000
M47 Spondylosis
0.908 0.092 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.907 0.093 0.000
K58 Irritable bowel syndrome
0.906 0.094 0.000
D64.9 Anaemia, unspecified
0.906 0.094 0.000
J30-J39 Other diseases of upper respiratory tract
0.905 0.095 0.000
D50.9 Iron deficiency anaemia, unspecified
0.904 0.096 0.000
K59 Other functional intestinal disorders
0.896 0.104 0.000
K76 Other diseases of liver
0.890 0.110 0.000
O60-O75 Complications of labour and delivery
0.888 0.112 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.886 0.114 0.000
Chapter VII Diseases of the eye and adnexa
0.881 0.119 0.000
M48 Other spondylopathies
0.880 0.120 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.876 0.124 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.873 0.127 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.872 0.128 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.867 0.133 0.000
A30-A49 Other bacterial diseases
0.862 0.138 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.861 0.139 0.000
S70-S79 Injuries to the hip and thigh
0.860 0.140 0.000
M16 Coxarthrosis [arthrosis of hip]
0.858 0.142 0.000
J95-J99 Other diseases of the respiratory system
0.857 0.142 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.856 0.144 0.000
I60 Subarachnoid haemorrhage
0.855 0.145 0.000
G40 Epilepsy
0.851 0.149 0.000
B95-B98 Bacterial, viral and other infectious agents
0.851 0.149 0.000
M17 Gonarthrosis [arthrosis of knee]
0.847 0.153 0.000
M18 Arthrosis of first carpometacarpal joint
0.840 0.160 0.000
I50 Heart failure
0.838 0.162 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.837 0.163 0.000
K63.8 Other specified diseases of intestine
0.837 0.163 0.000
R00 Abnormalities of heart beat
0.835 0.165 0.000
J60-J70 Lung diseases due to external agents
0.833 0.167 0.000
I35 Nonrheumatic aortic valve disorders
0.832 0.168 0.000
K35-K38 Diseases of appendix
0.832 0.168 0.000
I31 Other diseases of pericardium
0.829 0.171 0.000
N60-N64 Disorders of breast
0.827 0.173 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.825 0.175 0.000
M47.9 Spondylosis, unspecified
0.824 0.176 0.000
M05-M14 Inflammatory polyarthropathies
0.822 0.178 0.000
D70 Agranulocytosis
0.822 0.178 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.821 0.179 0.000
M80-M85 Disorders of bone density and structure
0.820 0.180 0.000
K76.8 Other specified diseases of liver
0.819 0.181 0.000
M25 Other joint disorders, not elsewhere classified
0.819 0.181 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.818 0.182 0.000
G90-G99 Other disorders of the nervous system
0.815 0.185 0.000
M48.0 Spinal stenosis
0.814 0.186 0.000
K59.0 Constipation
0.814 0.186 0.000
I69 Sequelae of cerebrovascular disease
0.814 0.186 0.000
I51 Complications and ill-defined descriptions of heart disease
0.814 0.186 0.000
J34 Other disorders of nose and nasal sinuses
0.814 0.186 0.000
I05-I09 Chronic rheumatic heart diseases
0.813 0.187 0.000
I67 Other cerebrovascular diseases
0.813 0.187 0.000
K90-K93 Other diseases of the digestive system
0.813 0.187 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.812 0.188 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.811 0.189 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.810 0.190 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.810 0.190 0.000
K55 Vascular disorders of intestine
0.809 0.191 0.000
K63.5 Polyp of colon
0.809 0.191 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.806 0.194 0.000
J32 Chronic sinusitis
0.805 0.195 0.000
I49 Other cardiac arrhythmias
0.804 0.196 0.000
N18.0 End-stage renal disease
0.803 0.197 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.800 0.200 0.000
I45 Other conduction disorders
0.799 0.201 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.797 0.203 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.796 0.204 0.000
S60-S69 Injuries to the wrist and hand
0.795 0.205 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.795 0.205 0.000
K65-K67 Diseases of peritoneum
0.793 0.207 0.000
I47 Paroxysmal tachycardia
0.793 0.207 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.789 0.211 0.000
M23 Internal derangement of knee
0.789 0.211 0.000
O16 Unspecified maternal hypertension
0.789 0.211 0.000
I42 Cardiomyopathy
0.788 0.212 0.000
D75 Other diseases of blood and blood-forming organs
0.784 0.216 0.000
M17.9 Gonarthrosis, unspecified
0.782 0.218 0.000
D51 Vitamin B12 deficiency anaemia
0.782 0.218 0.000
Chapter VIII Diseases of the ear and mastoid process
0.782 0.218 0.000
N99-N99 Other disorders of the genitourinary system
0.780 0.220 0.000
N10-N16 Renal tubulo-interstitial diseases
0.780 0.220 0.000
S90-S99 Injuries to the ankle and foot
0.779 0.221 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.776 0.224 0.000
M50-M54 Other dorsopathies
0.776 0.224 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.772 0.228 0.000
G50 Disorders of trigeminal nerve
0.770 0.230 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.767 0.233 0.000
M16.9 Coxarthrosis, unspecified
0.763 0.237 0.000
N18.2 Chronic kidney disease, stage 2
0.763 0.237 0.000
S72 Fracture of femur
0.763 0.237 0.000
B07 Viral warts
0.763 0.237 0.000
W00-W19 Falls
0.762 0.238 0.000
J98 Other respiratory disorders
0.759 0.241 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.759 0.241 0.000
D80-D89 Certain disorders involving the immune mechanism
0.759 0.241 0.000
M19.94 Arthrosis, unspecified (Hand)
0.759 0.241 0.000
M40-M43 Deforming dorsopathies
0.758 0.242 0.000
N00-N08 Glomerular diseases
0.758 0.242 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.757 0.243 0.000
R00.2 Palpitations
0.757 0.243 0.000
I99 Other and unspecified disorders of circulatory system
0.756 0.244 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.755 0.245 0.000
G47 Sleep disorders
0.755 0.245 0.000
R26 Abnormalities of gait and mobility
0.754 0.246 0.000
N64 Other disorders of breast
0.754 0.246 0.000
I35.0 Aortic (valve) stenosis
0.754 0.246 0.000
J40-J47 Chronic lower respiratory diseases
0.751 0.249 0.000
K60 Fissure and fistula of anal and rectal regions
0.750 0.250 0.000
G30-G32 Other degenerative diseases of the nervous system
0.749 0.251 0.000
I46 Cardiac arrest
0.749 0.251 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.746 0.254 0.000
S20-S29 Injuries to the thorax
0.745 0.255 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.745 0.255 0.000
I50.0 Congestive heart failure
0.745 0.255 0.000
W20-W49 Exposure to inanimate mechanical forces
0.745 0.255 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.744 0.256 0.000
M86-M90 Other osteopathies
0.743 0.257 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.742 0.258 0.000
I95 Hypotension
0.741 0.259 0.000
M48.06 Spinal stenosis (Lumbar region)
0.741 0.259 0.000
R06 Abnormalities of breathing
0.740 0.260 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.740 0.260 0.000
J69 Pneumonitis due to solids and liquids
0.739 0.261 0.000
A49 Bacterial infection of unspecified site
0.738 0.262 0.000
K92 Other diseases of digestive system
0.736 0.264 0.000
L60-L75 Disorders of skin appendages
0.736 0.264 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.735 0.265 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.735 0.265 0.000
G25 Other extrapyramidal and movement disorders
0.735 0.265 0.000
I31.3 Pericardial effusion (noninflammatory)
0.734 0.266 0.000
I51.8 Other ill-defined heart diseases
0.734 0.266 0.000
J90-J94 Other diseases of pleura
0.733 0.267 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.733 0.267 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.730 0.269 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.730 0.270 0.000
H53-H54 Visual disturbances and blindness
0.729 0.271 0.000
M47.8 Other spondylosis
0.728 0.272 0.000
H43-H45 Disorders of vitreous body and globe
0.727 0.273 0.000
O62 Abnormalities of forces of labour
0.727 0.273 0.000
J39 Other diseases of upper respiratory tract
0.726 0.274 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.725 0.275 0.000
Chapter XXII Codes for special purposes
0.725 0.275 0.000
K75 Other inflammatory liver diseases
0.724 0.276 0.000
G54 Nerve root and plexus disorders
0.724 0.276 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.724 0.276 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.723 0.276 0.000
O63 Long labour
0.722 0.278 0.000
M25.5 Pain in joint
0.722 0.278 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.721 0.279 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.721 0.279 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.719 0.281 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.718 0.282 0.000
G40.9 Epilepsy, unspecified
0.717 0.282 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.717 0.283 0.000
R00.0 Tachycardia, unspecified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
G70-G73 Diseases of myoneural junction and muscle
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
G51 Facial nerve disorders
0.716 0.284 0.000
N25-N29 Other disorders of kidney and ureter
0.716 0.284 0.000
D55-D59 Haemolytic anaemias
0.716 0.284 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.716 0.284 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.715 0.285 0.000
M34 Systemic sclerosis
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
B15-B19 Viral hepatitis
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.714 0.286 0.000
B35-B49 Mycoses
0.713 0.287 0.000
M47.2 Other spondylosis with radiculopathy
0.712 0.288 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.712 0.288 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.712 0.288 0.000
M15 Polyarthrosis
0.711 0.288 0.000
L40-L45 Papulosquamous disorders
0.711 0.289 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.711 0.289 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.711 0.289 0.000
I67.9 Cerebrovascular disease, unspecified
0.710 0.290 0.000
I00-I02 Acute rheumatic fever
0.710 0.290 0.000
O72 Postpartum haemorrhage
0.709 0.291 0.000
T66-T78 Other and unspecified effects of external causes
0.709 0.291 0.000
N18.5 Chronic kidney disease, stage 5
0.708 0.292 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.708 0.292 0.000
M46 Other inflammatory spondylopathies
0.707 0.293 0.000
H00 Hordeolum and chalazion
0.706 0.294 0.000
K63.9 Disease of intestine, unspecified
0.706 0.294 0.000
Q60-Q64 Congenital malformations of the urinary system
0.706 0.294 0.000
K12 Stomatitis and related lesions
0.706 0.294 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.704 0.295 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.704 0.296 0.000
M06 Other rheumatoid arthritis
0.704 0.296 0.000
J34.3 Hypertrophy of nasal turbinates
0.704 0.296 0.000
K02 Dental caries
0.702 0.298 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.701 0.299 0.000
N18.8 Other chronic renal failure
0.701 0.299 0.000
N18.4 Chronic kidney disease, stage 4
0.701 0.299 0.000
N18.1 Chronic kidney disease, stage 1
0.701 0.299 0.000
A07 Other protozoal intestinal diseases
0.701 0.299 0.000
A06 Amoebiasis
0.701 0.299 0.000
A05 Other bacterial foodborne intoxications
0.701 0.299 0.000
A03 Shigellosis
0.701 0.299 0.000
A02 Other Salmonella infections
0.701 0.299 0.000
A01 Typhoid and paratyphoid fevers
0.701 0.299 0.000
A00 Cholera
0.701 0.299 0.000
K72 Hepatic failure, not elsewhere classified
0.700 0.300 0.000
S00-S09 Injuries to the head
0.699 0.301 0.000
I52 Other heart disorders in diseases classified elsewhere
0.699 0.301 0.000
I48 Atrial fibrillation and flutter
0.699 0.301 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.699 0.301 0.000
I41 Myocarditis in diseases classified elsewhere
0.699 0.301 0.000
I40 Acute myocarditis
0.699 0.301 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.699 0.301 0.000
I37 Pulmonary valve disorders
0.699 0.301 0.000
I36 Nonrheumatic tricuspid valve disorders
0.699 0.301 0.000
I33 Acute and subacute endocarditis
0.699 0.301 0.000
I32 Pericarditis in diseases classified elsewhere
0.699 0.301 0.000
I30 Acute pericarditis
0.699 0.301 0.000
V10-V19 Pedal cyclist injured in transport accident
0.699 0.301 0.000
J36 Peritonsillar abscess
0.699 0.301 0.000
G24 Dystonia
0.698 0.302 0.000
G23 Other degenerative diseases of basal ganglia
0.698 0.302 0.000
G21 Secondary Parkinsonism
0.698 0.302 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.698 0.302 0.000
G22 Parkinsonism in diseases classified elsewhere
0.698 0.302 0.000
K70 Alcoholic liver disease
0.697 0.303 0.000
M49 Spondylopathies in diseases classified elsewhere
0.697 0.303 0.000
M45 Ankylosing spondylitis
0.697 0.303 0.000
A08 Viral and other specified intestinal infections
0.696 0.304 0.000
K14 Diseases of tongue
0.696 0.304 0.000
J32.0 Chronic maxillary sinusitis
0.696 0.304 0.000
S62 Fracture at wrist and hand level
0.695 0.305 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.694 0.306 0.000
D50.8 Other iron deficiency anaemias
0.694 0.306 0.000
T88.4 Failed or difficult intubation
0.693 0.307 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.693 0.307 0.000
G44 Other headache syndromes
0.693 0.307 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.693 0.307 0.000
D53 Other nutritional anaemias
0.692 0.308 0.000
D52 Folate deficiency anaemia
0.692 0.308 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.692 0.308 0.000
T42.4 Benzodiazepines
0.692 0.308 0.000
D61 Other aplastic anaemias
0.691 0.309 0.000
H02 Other disorders of eyelid
0.691 0.309 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.691 0.309 0.000
M19.98 Arthrosis, unspecified (Other)
0.690 0.310 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.690 0.310 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.689 0.311 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.689 0.311 0.000
O85-O92 Complications predominantly related to the puerperium
0.689 0.311 0.000
H10-H13 Disorders of conjunctiva
0.689 0.311 0.000
D75.1 Secondary polycythaemia
0.688 0.312 0.000
N17 Acute renal failure
0.688 0.312 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.687 0.313 0.000
I61 Intracerebral haemorrhage
0.687 0.313 0.000
M19.0 Primary arthrosis of other joints
0.687 0.313 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.687 0.313 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.686 0.313 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.686 0.314 0.000
D62 Acute posthaemorrhagic anaemia
0.686 0.314 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.685 0.315 0.000
O00-O08 Pregnancy with abortive outcome
0.685 0.315 0.000
M21 Other acquired deformities of limbs
0.684 0.315 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.683 0.317 0.000
M19.8 Other specified arthrosis
0.683 0.317 0.000
M19.2 Other secondary arthrosis
0.683 0.317 0.000
M19.1 Posttraumatic arthrosis of other joints
0.683 0.317 0.000
K04 Diseases of pulp and periapical tissues
0.682 0.318 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.682 0.318 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.682 0.318 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.682 0.318 0.000
R06.5 Mouth breathing
0.682 0.318 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.681 0.319 0.000
T87 Complications peculiar to reattachment and amputation
0.680 0.320 0.000
T86 Failure and rejection of transplanted organs and tissues
0.680 0.320 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.680 0.320 0.000
K83 Other diseases of biliary tract
0.680 0.320 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.679 0.321 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.679 0.321 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.679 0.321 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.679 0.321 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.679 0.321 0.000
J98.4 Other disorders of lung
0.678 0.322 0.000
R41.0 Disorientation, unspecified
0.678 0.322 0.000
K08 Other disorders of teeth and supporting structures
0.678 0.322 0.000
L20-L30 Dermatitis and eczema
0.678 0.322 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.678 0.322 0.000
J30 Vasomotor and allergic rhinitis
0.676 0.324 0.000
T81 Complications of procedures, not elsewhere classified
0.676 0.324 0.000
K55.2 Angiodysplasia of colon
0.676 0.324 0.000
M25.4 Effusion of joint
0.676 0.324 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.675 0.325 0.000
K77 Liver disorders in diseases classified elsewhere
0.675 0.325 0.000
K73 Chronic hepatitis, not elsewhere classified
0.675 0.325 0.000
K71 Toxic liver disease
0.675 0.325 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.673 0.326 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.673 0.326 0.000
I62 Other nontraumatic intracranial haemorrhage
0.673 0.326 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.673 0.327 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.673 0.327 0.000
K07 Dentofacial anomalies [including malocclusion]
0.673 0.327 0.000
A41 Other septicaemia
0.672 0.328 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.672 0.328 0.000
K59.8 Other specified functional intestinal disorders
0.672 0.328 0.000
G50.0 Trigeminal neuralgia
0.672 0.328 0.000
X60-X84 Intentional self-harm
0.671 0.329 0.000
J69.0 Pneumonitis due to food and vomit
0.671 0.329 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.671 0.329 0.000
G41 Status epilepticus
0.671 0.329 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.671 0.329 0.000
K63.1 Perforation of intestine (nontraumatic)
0.670 0.329 0.000
K92.0 Haematemesis
0.670 0.330 0.000
I49.9 Cardiac arrhythmia, unspecified
0.669 0.331 0.000
I10-I15 Hypertensive diseases
0.669 0.331 0.000
K63.4 Enteroptosis
0.669 0.331 0.000
K63.2 Fistula of intestine
0.669 0.331 0.000
K63.0 Abscess of intestine
0.669 0.331 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.668 0.332 0.000
K80 Cholelithiasis
0.668 0.332 0.000
D50.1 Sideropenic dysphagia
0.668 0.332 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.667 0.333 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.333 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.667 0.333 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.667 0.333 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.667 0.333 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.667 0.333 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.667 0.333 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.667 0.333 0.000
T36 Poisoning by systemic antibiotics
0.667 0.333 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.667 0.333 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.667 0.333 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.667 0.333 0.000
N40-N51 Diseases of male genital organs
0.667 0.333 0.000
S72.0 Fracture of neck of femur
0.667 0.333 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.667 0.333 0.000
R02 Gangrene, not elsewhere classified
0.667 0.333 0.000
K76.6 Portal hypertension
0.666 0.334 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.666 0.334 0.000
R03.1 Nonspecific low blood-pressure reading
0.665 0.335 0.000
D64.8 Other specified anaemias
0.665 0.335 0.000
D64.4 Congenital dyserythropoietic anaemia
0.665 0.335 0.000
D64.3 Other sideroblastic anaemias
0.665 0.335 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.665 0.335 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.665 0.335 0.000
D64.0 Hereditary sideroblastic anaemia
0.665 0.335 0.000
N30-N39 Other diseases of urinary system
0.665 0.335 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.665 0.335 0.000
Y35-Y36 Legal intervention and operations of war
0.665 0.335 0.000
Y10-Y34 Event of undetermined intent
0.665 0.335 0.000
Y00-Y09 Assault
0.665 0.335 0.000
X85-X99 Assault
0.665 0.335 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.665 0.335 0.000
X50-X57 Overexertion, travel and privation
0.665 0.335 0.000
X30-X39 Exposure to forces of nature
0.665 0.335 0.000
X20-X29 Contact with venomous animals and plants
0.665 0.335 0.000
X10-X19 Contact with heat and hot substances
0.665 0.335 0.000
X00-X09 Exposure to smoke, fire and flames
0.665 0.335 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.665 0.335 0.000
W75-W84 Other accidental threats to breathing
0.665 0.335 0.000
W65-W74 Accidental drowning and submersion
0.665 0.335 0.000
W50-W64 Exposure to animate mechanical forces
0.665 0.335 0.000
V98-V99 Other and unspecified transport accidents
0.665 0.335 0.000
V95-V97 Air and space transport accidents
0.665 0.335 0.000
V90-V94 Water transport accidents
0.665 0.335 0.000
V80-V89 Other land transport accidents
0.665 0.335 0.000
V70-V79 Bus occupant injured in transport accident
0.665 0.335 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.665 0.335 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.665 0.335 0.000
V40-V49 Car occupant injured in transport accident
0.665 0.335 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.665 0.335 0.000
V20-V29 Motorcycle rider injured in transport accident
0.665 0.335 0.000
V01-V09 Pedestrian injured in transport accident
0.665 0.335 0.000
M35 Other systemic involvement of connective tissue
0.663 0.337 0.000
G43 Migraine
0.663 0.337 0.000
I08 Multiple valve diseases
0.663 0.337 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.662 0.338 0.000
M22 Disorders of patella
0.662 0.338 0.000
G56 Mononeuropathies of upper limb
0.662 0.338 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.661 0.339 0.000
M33 Dermatopolymyositis
0.661 0.339 0.000
M32 Systemic lupus erythematosus
0.661 0.339 0.000
M30 Polyarteritis nodosa and related conditions
0.661 0.339 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.660 0.340 0.000
I47.2 Ventricular tachycardia
0.660 0.340 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.660 0.340 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.660 0.340 0.000
K01 Embedded and impacted teeth
0.659 0.340 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.658 0.342 0.000
D74 Methaemoglobinaemia
0.658 0.342 0.000
D72 Other disorders of white blood cells
0.658 0.342 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.658 0.342 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.658 0.342 0.000
S80-S89 Injuries to the knee and lower leg
0.657 0.343 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.657 0.343 0.000
R00.1 Bradycardia, unspecified
0.656 0.344 0.000
M17.1 Other primary gonarthrosis
0.655 0.345 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.655 0.345 0.000
R40 Somnolence, stupor and coma
0.654 0.346 0.000
S50-S59 Injuries to the elbow and forearm
0.654 0.346 0.000
Chapter XXI Factors influencing health status and contact with health services
0.652 0.348 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.652 0.348 0.000
M47.1 Other spondylosis with myelopathy
0.651 0.349 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.651 0.349 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.650 0.350 0.000
G58 Other mononeuropathies
0.650 0.350 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.650 0.350 0.000
G52 Disorders of other cranial nerves
0.650 0.350 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.650 0.350 0.000
A49.0 Staphylococcal infection, unspecified
0.650 0.350 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.650 0.350 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.649 0.351 0.000
K37 Unspecified appendicitis
0.649 0.351 0.000
J37 Chronic laryngitis and laryngotracheitis
0.649 0.351 0.000
J32.4 Chronic pansinusitis
0.648 0.352 0.000
I38 Endocarditis, valve unspecified
0.648 0.352 0.000
M47.82 Other spondylosis (Cervical region)
0.646 0.354 0.000
I42.0 Dilated cardiomyopathy
0.645 0.355 0.000
H80-H83 Diseases of inner ear
0.644 0.355 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.644 0.355 0.000
R30-R39 Symptoms and signs involving the urinary system
0.644 0.356 0.000
A04 Other bacterial intestinal infections
0.643 0.356 0.000
N64.5 Other signs and symptoms in breast
0.643 0.357 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.642 0.358 0.000
K59.9 Functional intestinal disorder, unspecified
0.642 0.358 0.000
K59.4 Anal spasm
0.642 0.358 0.000
K59.3 Megacolon, not elsewhere classified
0.642 0.358 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.642 0.358 0.000
K59.1 Functional diarrhoea
0.642 0.358 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.642 0.358 0.000
K35 Acute appendicitis
0.642 0.358 0.000
J35 Chronic diseases of tonsils and adenoids
0.642 0.358 0.000
M48.09 Spinal stenosis (Site unspecified)
0.640 0.360 0.000
K38 Other diseases of appendix
0.640 0.360 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.640 0.360 0.000
K76.7 Hepatorenal syndrome
0.638 0.362 0.000
K76.5 Hepatic veno-occlusive disease
0.638 0.362 0.000
K76.4 Peliosis hepatis
0.638 0.362 0.000
K76.3 Infarction of liver
0.638 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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