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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs59659806
log Bayes Factor = 5.44831
Chromosome 15   position 38,919,964  (GRCh37) Explore rs59659806 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E03 Other hypothyroidism
0.999 0.001 0.000
E10.9 Without complications
0.999 0.001 0.000
E03.9 Hypothyroidism, unspecified
0.997 0.003 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.985 0.015 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.972 0.028 0.000
M65-M68 Disorders of synovium and tendon
0.965 0.035 0.000
M20-M25 Other joint disorders
0.964 0.036 0.000
M65 Synovitis and tenosynovitis
0.961 0.039 0.000
E50-E64 Other nutritional deficiencies
0.960 0.040 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.956 0.044 0.000
M05-M14 Inflammatory polyarthropathies
0.955 0.045 0.000
E05.9 Thyrotoxicosis, unspecified
0.949 0.051 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.944 0.056 0.000
E20-E35 Disorders of other endocrine glands
0.937 0.063 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.936 0.064 0.000
E10.1 With ketoacidosis
0.935 0.065 0.000
M31 Other necrotising vasculopathies
0.929 0.071 0.000
E53 Deficiency of other B group vitamins
0.913 0.087 0.000
M24 Other specific joint derangements
0.910 0.090 0.000
M15-M19 Arthrosis
0.901 0.099 0.000
E10.0 With coma
0.891 0.109 0.000
M07 Psoriatic and enteropathic arthropathies
0.890 0.110 0.000
E10.3 With ophthalmic complications
0.888 0.112 0.000
E53.8 Deficiency of other specified B group vitamins
0.882 0.118 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.880 0.120 0.000
Chapter XX External causes of morbidity and mortality
0.878 0.122 0.000
E29 Testicular dysfunction
0.877 0.123 0.000
# Top node
0.877 0.123 0.000
E22 Hyperfunction of pituitary gland
0.870 0.130 0.000
M06 Other rheumatoid arthritis
0.870 0.130 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.867 0.133 0.000
E07 Other disorders of thyroid
0.862 0.138 0.000
M24.2 Disorder of ligament
0.860 0.140 0.000
Y86 Sequelae of other accidents
0.859 0.141 0.000
M19 Other arthrosis
0.857 0.143 0.000
M22 Disorders of patella
0.854 0.146 0.000
M31.3 Wegener's granulomatosis
0.854 0.146 0.000
E03.8 Other specified hypothyroidism
0.854 0.146 0.000
M30 Polyarteritis nodosa and related conditions
0.852 0.148 0.000
M05 Seropositive rheumatoid arthritis
0.851 0.149 0.000
Y85 Sequelae of transport accidents
0.846 0.154 0.000
M07.3 Other psoriatic arthropathies
0.844 0.156 0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.834 0.166 0.000
E29.1 Testicular hypofunction
0.834 0.166 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.833 0.167 0.000
E61 Deficiency of other nutrient elements
0.826 0.174 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.824 0.176 0.000
M19.0 Primary arthrosis of other joints
0.818 0.182 0.000
M70-M79 Other soft tissue disorders
0.813 0.187 0.000
M21 Other acquired deformities of limbs
0.811 0.189 0.000
Y88 Sequelae of surgical and medical care as external cause
0.805 0.195 0.000
E11 Non-insulin-dependent diabetes mellitus
0.803 0.197 0.000
M06.4 Inflammatory polyarthropathy
0.795 0.205 0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.793 0.207 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.790 0.210 0.000
Y85.0 Sequelae of motor-vehicle accident
0.790 0.210 0.000
M12 Other specific arthropathies
0.788 0.212 0.000
E10.8 With unspecified complications
0.780 0.220 0.000
M60-M63 Disorders of muscles
0.776 0.223 0.000
M35 Other systemic involvement of connective tissue
0.773 0.227 0.000
M31.1 Thrombotic microangiopathy
0.771 0.229 0.000
J93 Pneumothorax
0.768 0.232 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.767 0.233 0.000
J90-J94 Other diseases of pleura
0.763 0.237 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.762 0.238 0.000
E14 Unspecified diabetes mellitus
0.761 0.239 0.000
Chapter X Diseases of the respiratory system
0.760 0.240 0.000
E05.8 Other thyrotoxicosis
0.759 0.241 0.000
J93.9 Pneumothorax, unspecified
0.758 0.242 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.758 0.242 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.756 0.244 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.755 0.245 0.000
E27 Other disorders of adrenal gland
0.753 0.247 0.000
E07.8 Other specified disorders of thyroid
0.751 0.249 0.000
J93.1 Other spontaneous pneumothorax
0.750 0.250 0.000
M22.4 Chondromalacia patellae
0.749 0.251 0.000
W50-W64 Exposure to animate mechanical forces
0.746 0.254 0.000
M18 Arthrosis of first carpometacarpal joint
0.745 0.255 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.741 0.259 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.740 0.260 0.000
M77 Other enthesopathies
0.739 0.261 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.737 0.263 0.000
E58 Dietary calcium deficiency
0.735 0.265 0.000
E03.1 Congenital hypothyroidism without goitre
0.732 0.268 0.000
M00-M03 Infectious arthropathies
0.732 0.268 0.000
V20-V29 Motorcycle rider injured in transport accident
0.732 0.268 0.000
M31.7 Microscopic polyangiitis
0.729 0.271 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.727 0.273 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.726 0.274 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.726 0.274 0.000
E11.1 With ketoacidosis
0.725 0.275 0.000
E10.6 With other specified complications
0.725 0.275 0.000
M86-M90 Other osteopathies
0.723 0.277 0.000
W20-W49 Exposure to inanimate mechanical forces
0.723 0.277 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.722 0.278 0.000
M19.2 Other secondary arthrosis
0.721 0.279 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.721 0.279 0.000
M24.28 Disorder of ligament (Other)
0.720 0.280 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.720 0.280 0.000
Y00-Y09 Assault
0.719 0.281 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E03.5 Myxoedema coma
0.716 0.284 0.000
E03.4 Atrophy of thyroid (acquired)
0.716 0.284 0.000
E03.3 Postinfectious hypothyroidism
0.716 0.284 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.716 0.284 0.000
M31.9 Necrotising vasculopathy, unspecified
0.716 0.284 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.715 0.285 0.000
M67 Other disorders of synovium and tendon
0.712 0.288 0.000
M14 Arthropathies in other diseases classified elsewhere
0.709 0.291 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.708 0.292 0.000
E05.5 Thyroid crisis or storm
0.706 0.293 0.000
E05.4 Thyrotoxicosis factitia
0.706 0.293 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.706 0.293 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.706 0.293 0.000
E11.9 Without complications
0.706 0.294 0.000
M24.5 Contracture of joint
0.705 0.295 0.000
M35.0 Sicca syndrome [Sjogren]
0.704 0.296 0.000
M65.8 Other synovitis and tenosynovitis
0.703 0.297 0.000
E13 Other specified diabetes mellitus
0.701 0.299 0.000
M06.0 Seronegative rheumatoid arthritis
0.698 0.302 0.000
E51 Thiamine deficiency
0.695 0.304 0.000
M24.7 Protrusio acetabuli
0.693 0.306 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.692 0.308 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.692 0.308 0.000
E22.0 Acromegaly and pituitary gigantism
0.691 0.309 0.000
E61.1 Iron deficiency
0.691 0.309 0.000
M22.3 Other derangements of patella
0.691 0.309 0.000
M24.6 Ankylosis of joint
0.691 0.309 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.690 0.310 0.000
M06.3 Rheumatoid nodule
0.690 0.310 0.000
M24.24 Disorder of ligament (Hand)
0.689 0.311 0.000
M65.2 Calcific tendinitis
0.689 0.311 0.000
M65.0 Abscess of tendon sheath
0.689 0.311 0.000
V95-V97 Air and space transport accidents
0.689 0.311 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.688 0.312 0.000
E63 Other nutritional deficiencies
0.688 0.312 0.000
E56 Other vitamin deficiencies
0.688 0.312 0.000
E50 Vitamin A deficiency
0.688 0.312 0.000
E60 Dietary zinc deficiency
0.688 0.312 0.000
E59 Dietary selenium deficiency
0.688 0.312 0.000
E54 Ascorbic acid deficiency
0.688 0.312 0.000
E52 Niacin deficiency [pellagra]
0.688 0.312 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.688 0.312 0.000
M19.8 Other specified arthrosis
0.688 0.312 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.688 0.312 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.686 0.314 0.000
M25 Other joint disorders, not elsewhere classified
0.685 0.315 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.685 0.315 0.000
M08 Juvenile arthritis
0.685 0.315 0.000
V10-V19 Pedal cyclist injured in transport accident
0.683 0.317 0.000
M77.9 Enthesopathy, unspecified
0.683 0.317 0.000
M40-M43 Deforming dorsopathies
0.683 0.317 0.000
Y10-Y34 Event of undetermined intent
0.682 0.318 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.679 0.321 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.679 0.321 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.679 0.321 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.679 0.321 0.000
M30.0 Polyarteritis nodosa
0.677 0.323 0.000
X20-X29 Contact with venomous animals and plants
0.676 0.324 0.000
E11.6 With other specified complications
0.676 0.324 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.676 0.324 0.000
J60-J70 Lung diseases due to external agents
0.676 0.324 0.000
M12.3 Palindromic rheumatism
0.676 0.324 0.000
X00-X09 Exposure to smoke, fire and flames
0.674 0.326 0.000
M21.1 Varus deformity, not elsewhere classified
0.673 0.327 0.000
V98-V99 Other and unspecified transport accidents
0.673 0.327 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.672 0.328 0.000
E32 Diseases of thymus
0.672 0.328 0.000
E31 Polyglandular dysfunction
0.672 0.328 0.000
E30 Disorders of puberty, not elsewhere classified
0.672 0.328 0.000
E25 Adrenogenital disorders
0.672 0.328 0.000
X10-X19 Contact with heat and hot substances
0.671 0.329 0.000
M13 Other arthritis
0.669 0.331 0.000
M17 Gonarthrosis [arthrosis of knee]
0.668 0.332 0.000
M22.2 Patellofemoral disorders
0.667 0.333 0.000
E20 Hypoparathyroidism
0.667 0.333 0.000
M31.8 Other specified necrotising vasculopathies
0.666 0.334 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.666 0.334 0.000
M31.2 Lethal midline granuloma
0.666 0.334 0.000
M31.0 Hypersensitivity angiitis
0.666 0.334 0.000
E26 Hyperaldosteronism
0.665 0.335 0.000
E04 Other non-toxic goitre
0.665 0.335 0.000
M24.26 Disorder of ligament (Lower leg)
0.664 0.336 0.000
E14.3 With ophthalmic complications
0.664 0.336 0.000
S20-S29 Injuries to the thorax
0.664 0.336 0.000
M91-M94 Chondropathies
0.663 0.337 0.000
J91 Pleural effusion in conditions classified elsewhere
0.663 0.337 0.000
M24.1 Other articular cartilage disorders
0.662 0.338 0.000
T92 Sequelae of injuries of upper limb
0.661 0.339 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.661 0.339 0.000
E34 Other endocrine disorders
0.660 0.339 0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.660 0.339 0.000
S20 Superficial injury of thorax
0.659 0.341 0.000
E10.5 With peripheral circulatory complications
0.659 0.341 0.000
E61.2 Magnesium deficiency
0.658 0.342 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.656 0.344 0.000
M33 Dermatopolymyositis
0.656 0.344 0.000
J94 Other pleural conditions
0.656 0.344 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.656 0.344 0.000
M34 Systemic sclerosis
0.656 0.344 0.000
M72 Fibroblastic disorders
0.656 0.344 0.000
E53.1 Pyridoxine deficiency
0.654 0.345 0.000
E53.0 Riboflavin deficiency
0.654 0.345 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.653 0.347 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.652 0.348 0.000
M24.9 Joint derangement, unspecified
0.652 0.348 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.649 0.351 0.000
M05.8 Other seropositive rheumatoid arthritis
0.649 0.351 0.000
V90-V94 Water transport accidents
0.648 0.351 0.000
M15 Polyarthrosis
0.648 0.352 0.000
Chapter VIII Diseases of the ear and mastoid process
0.645 0.355 0.000
W55 Bitten or struck by other mammals
0.645 0.355 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.645 0.355 0.000
E28 Ovarian dysfunction
0.645 0.355 0.000
E07.9 Disorder of thyroid, unspecified
0.644 0.356 0.000
M66 Spontaneous rupture of synovium and tendon
0.643 0.357 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.643 0.357 0.000
M07.6 Other enteropathic arthropathies
0.638 0.361 0.000
M07.5 Arthropathy in ulcerative colitis
0.638 0.361 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.638 0.361 0.000
M07.2 Psoriatic spondylitis
0.638 0.361 0.000
M07.1 Arthritis mutilans
0.638 0.361 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.638 0.361 0.000
W75-W84 Other accidental threats to breathing
0.638 0.362 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.636 0.364 0.000
M21.3 Wrist or foot drop (acquired)
0.633 0.367 0.000
M13.0 Polyarthritis, unspecified
0.633 0.367 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.632 0.368 0.000
M35.3 Polymyalgia rheumatica
0.632 0.368 0.000
Q00-Q07 Congenital malformations of the nervous system
0.632 0.368 0.000
E53.9 Vitamin B deficiency, unspecified
0.631 0.369 0.000
M86 Osteomyelitis
0.630 0.370 0.000
M21.7 Unequal limb length (acquired)
0.630 0.370 0.000
Y35-Y36 Legal intervention and operations of war
0.630 0.370 0.000
X85-X99 Assault
0.630 0.370 0.000
X30-X39 Exposure to forces of nature
0.630 0.370 0.000
W65-W74 Accidental drowning and submersion
0.630 0.370 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.630 0.370 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.630 0.370 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.630 0.370 0.000
E29.9 Testicular dysfunction, unspecified
0.629 0.371 0.000
E29.8 Other testicular dysfunction
0.629 0.371 0.000
E29.0 Testicular hyperfunction
0.629 0.371 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.628 0.371 0.000
J94.8 Other specified pleural conditions
0.626 0.374 0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures
0.626 0.374 0.000
E10.2 With renal complications
0.625 0.374 0.000
M24.23 Disorder of ligament (Forearm)
0.625 0.374 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.624 0.376 0.000
M19.27 Other secondary arthrosis (Ankle and foot)
0.624 0.376 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.624 0.376 0.000
E22.8 Other hyperfunction of pituitary gland
0.624 0.376 0.000
E11.3 With ophthalmic complications
0.624 0.376 0.000
M06.8 Other specified rheumatoid arthritis
0.623 0.376 0.000
M06.2 Rheumatoid bursitis
0.623 0.376 0.000
M06.1 Adult-onset Still's disease
0.623 0.376 0.000
E27.1 Primary adrenocortical insufficiency
0.623 0.377 0.000
V40-V49 Car occupant injured in transport accident
0.622 0.378 0.000
W22 Striking against or struck by other objects
0.622 0.378 0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec
0.622 0.378 0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other
0.622 0.378 0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot
0.622 0.378 0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg
0.622 0.378 0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh
0.622 0.378 0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm
0.622 0.378 0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region
0.622 0.378 0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)
0.622 0.378 0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.620 0.380 0.000
E23 Hypofunction and other disorders of pituitary gland
0.620 0.380 0.000
M71 Other bursopathies
0.619 0.381 0.000
E07.1 Dyshormogenetic goitre
0.618 0.382 0.000
E07.0 Hypersecretion of calcitonin
0.618 0.382 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.618 0.382 0.000
M65.1 Other infective (teno)synovitis
0.617 0.382 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.617 0.383 0.000
Q24 Other congenital malformations of heart
0.617 0.383 0.000
M76 Enthesopathies of lower limb, excluding foot
0.617 0.383 0.000
M24.29 Disorder of ligament (Site unspecified)
0.616 0.383 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.616 0.383 0.000
M24.22 Disorder of ligament (Upper arm)
0.616 0.383 0.000
M24.20 Disorder of ligament (Multiple sites)
0.616 0.383 0.000
M21.9 Acquired deformity of limb, unspecified
0.616 0.384 0.000
M77.91 Enthesopathy, unspecified (Shoulder region)
0.615 0.385 0.000
M62 Other disorders of muscle
0.613 0.387 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.613 0.387 0.000
M22.1 Recurrent subluxation of patella
0.613 0.387 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.611 0.389 0.000
M02 Reactive arthropathies
0.611 0.389 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.611 0.389 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.611 0.389 0.000
M30.2 Juvenile polyarteritis
0.611 0.389 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.610 0.390 0.000
M05.2 Rheumatoid vasculitis
0.610 0.390 0.000
M05.1 Rheumatoid lung disease
0.610 0.390 0.000
M05.0 Felty's syndrome
0.610 0.390 0.000
S40-S49 Injuries to the shoulder and upper arm
0.609 0.391 0.000
E14.6 With other specified complications
0.608 0.391 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.608 0.392 0.000
T92.1 Sequelae of fracture of arm
0.608 0.392 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.607 0.393 0.000
M24.0 Loose body in joint
0.607 0.393 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.607 0.393 0.000
V70-V79 Bus occupant injured in transport accident
0.606 0.394 0.000
M17.0 Primary gonarthrosis, bilateral
0.606 0.394 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.606 0.394 0.000
M07.38 Other psoriatic arthropathies (Other)
0.605 0.395 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.605 0.395 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.605 0.395 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.605 0.395 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.605 0.395 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.605 0.395 0.000
M22.9 Disorder of patella, unspecified
0.605 0.395 0.000
M77.5 Other enthesopathy of foot
0.604 0.396 0.000
Y89 Sequelae of other external causes
0.604 0.396 0.000
E06 Thyroiditis
0.604 0.396 0.000
M22.0 Recurrent dislocation of patella
0.603 0.396 0.000
M19.1 Posttraumatic arthrosis of other joints
0.601 0.399 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.600 0.400 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.599 0.401 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.598 0.402 0.000
M25.9 Joint disorder, unspecified
0.597 0.403 0.000
M45-M49 Spondylopathies
0.595 0.405 0.000
E10.4 With neurological complications
0.595 0.405 0.000
E14.1 With ketoacidosis
0.593 0.407 0.000
E61.9 Deficiency of nutrient element, unspecified
0.592 0.408 0.000
E61.8 Deficiency of other specified nutrient elements
0.592 0.408 0.000
E61.7 Deficiency of multiple nutrient elements
0.592 0.408 0.000
E61.6 Vanadium deficiency
0.592 0.408 0.000
E61.5 Molybdenum deficiency
0.592 0.408 0.000
E61.4 Chromium deficiency
0.592 0.408 0.000
E61.3 Manganese deficiency
0.592 0.408 0.000
E61.0 Copper deficiency
0.592 0.408 0.000
T00-T07 Injuries involving multiple body regions
0.592 0.408 0.000
W55.0 Home
0.591 0.409 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.589 0.411 0.000
M25.7 Osteophyte
0.589 0.411 0.000
S90-S99 Injuries to the ankle and foot
0.588 0.412 0.000
M60 Myositis
0.588 0.412 0.000
T90 Sequelae of injuries of head
0.587 0.413 0.000
M19.08 Primary arthrosis of other joints (Other)
0.587 0.413 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.587 0.413 0.000
M24.21 Disorder of ligament (Shoulder region)
0.587 0.413 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.587 0.413 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.583 0.417 0.000
S50-S59 Injuries to the elbow and forearm
0.583 0.417 0.000
Q60-Q64 Congenital malformations of the urinary system
0.583 0.417 0.000
M21.8 Other specified acquired deformities of limbs
0.582 0.418 0.000
X50-X57 Overexertion, travel and privation
0.581 0.419 0.000
V23.4 Driver injured in traffic accident
0.580 0.420 0.000
M31.6 Other giant cell arteritis
0.579 0.421 0.000
V01-V09 Pedestrian injured in transport accident
0.579 0.421 0.000
M12.30 Palindromic rheumatism (Multiple sites)
0.579 0.421 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.578 0.422 0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use
0.577 0.423 0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use
0.577 0.423 0.000
X58 Exposure to other specified factors
0.577 0.423 0.000
Q23 Congenital malformations of aortic and mitral valves
0.577 0.423 0.000
Y04 Assault by bodily force
0.577 0.423 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.576 0.424 0.000
E13.3 With ophthalmic complications
0.576 0.424 0.000
T92.0 Sequelae of open wound of upper limb
0.576 0.424 0.000
J69 Pneumonitis due to solids and liquids
0.576 0.424 0.000
M32 Systemic lupus erythematosus
0.576 0.424 0.000
E11.7 With multiple complications
0.576 0.424 0.000
V80-V89 Other land transport accidents
0.574 0.426 0.000
X59 Exposure to unspecified factor
0.574 0.426 0.000
E34.9 Endocrine disorder, unspecified
0.573 0.427 0.000
S70-S79 Injuries to the hip and thigh
0.572 0.428 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.571 0.429 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.570 0.430 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.570 0.430 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.570 0.430 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.570 0.430 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.570 0.430 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.570 0.430 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.570 0.430 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.570 0.430 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.570 0.430 0.000
M21.2 Flexion deformity
0.570 0.430 0.000
E04.9 Non-toxic goitre, unspecified
0.569 0.431 0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb
0.568 0.432 0.000
J93.0 Spontaneous tension pneumothorax
0.567 0.432 0.000
Q25 Congenital malformations of great arteries
0.567 0.433 0.000
M21.4 Flat foot [pes planus] (acquired)
0.567 0.433 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.566 0.434 0.000
M17.1 Other primary gonarthrosis
0.566 0.434 0.000
E14.5 With peripheral circulatory complications
0.566 0.434 0.000
E40-E46 Malnutrition
0.565 0.435 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.565 0.435 0.000
M12.5 Traumatic arthropathy
0.565 0.435 0.000
M12.4 Intermittent hydrarthrosis
0.565 0.435 0.000
M12.1 Kaschin-Beck disease
0.565 0.435 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.565 0.435 0.000
M11 Other crystal arthropathies
0.565 0.435 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.564 0.436 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.564 0.436 0.000
M48 Other spondylopathies
0.564 0.436 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.563 0.437 0.000
M77.93 Enthesopathy, unspecified (Forearm)
0.563 0.437 0.000
Q24.5 Malformation of coronary vessels
0.562 0.438 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.562 0.438 0.000
E14.4 With neurological complications
0.562 0.438 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.561 0.438 0.000
W60 Contact with plant thorns and spines and sharp leaves
0.561 0.439 0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.561 0.439 0.000
M24.51 Contracture of joint (Shoulder region)
0.560 0.440 0.000
X60-X84 Intentional self-harm
0.560 0.440 0.000
J00-J06 Acute upper respiratory infections
0.560 0.440 0.000
M24.57 Contracture of joint (Ankle and foot)
0.560 0.440 0.000
W44 Foreign body entering into or through eye or natural orifice
0.560 0.440 0.000
M72.2 Plantar fascial fibromatosis
0.559 0.441 0.000
Chapter V Mental and behavioural disorders
0.559 0.441 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.558 0.441 0.000
W22.9 Unspecified place
0.558 0.442 0.000
Y09 Assault by unspecified means
0.557 0.443 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.557 0.443 0.000
M61 Calcification and ossification of muscle
0.557 0.443 0.000
W34 Discharge from other and unspecified firearms
0.555 0.445 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.555 0.445 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.554 0.446 0.000
M35.8 Other specified systemic involvement of connective tissue
0.554 0.446 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.554 0.446 0.000
M35.5 Multifocal fibrosclerosis
0.554 0.446 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.554 0.446 0.000
T91 Sequelae of injuries of neck and trunk
0.554 0.446 0.000
V19 Pedal cyclist injured in other and unspecified transport accidents
0.554 0.446 0.000
M67.0 Short Achilles tendon (acquired)
0.553 0.447 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.553 0.447 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.552 0.448 0.000
M86.6 Other chronic osteomyelitis
0.552 0.448 0.000
M70.6 Trochanteric bursitis
0.552 0.448 0.000
M12.2 Villonodular synovitis (pigmented)
0.552 0.448 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.552 0.448 0.000
W45 Foreign body or object entering through skin
0.552 0.448 0.000
Q07 Other congenital malformations of nervous system
0.551 0.449 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.550 0.450 0.000
S50 Superficial injury of forearm
0.550 0.450 0.000
V11 Pedal cyclist injured in collision with other pedal cycle
0.547 0.453 0.000
M77.1 Lateral epicondylitis
0.547 0.453 0.000
E55 Vitamin D deficiency
0.546 0.453 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.547 0.453 0.000
M19.89 Other specified arthrosis (Site unspecified)
0.546 0.454 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.546 0.454 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.546 0.454 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.546 0.454 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.546 0.454 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.546 0.454 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.546 0.454 0.000
E14.7 With multiple complications
0.546 0.454 0.000
E14.2 Withrenal complications
0.546 0.454 0.000
E14.0 With coma
0.546 0.454 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.545 0.455 0.000
E11.4 With neurological complications
0.544 0.456 0.000
W27 Contact with nonpowered hand tool
0.543 0.457 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.542 0.458 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.542 0.458 0.000
M36.3 Arthropathy in other blood disorders
0.542 0.458 0.000
M36.2 Haemophilic arthropathy
0.542 0.458 0.000
M36.1 Arthropathy in neoplastic disease
0.542 0.458 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.542 0.458 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.542 0.458 0.000
V96 Accident to nonpowered aircraft causing injury to occupant
0.542 0.458 0.000
Y28 Contact with sharp object, undetermined intent
0.542 0.458 0.000
M67.1 Other contracture of tendon (sheath)
0.542 0.458 0.000
M70.5 Other bursitis of knee
0.541 0.459 0.000
M70.2 Olecranon bursitis
0.541 0.459 0.000
T98 Sequelae of other and unspecified effects of external causes
0.541 0.459 0.000
M94 Other disorders of cartilage
0.540 0.460 0.000
M19.06 Primary arthrosis of other joints-Lower leg
0.540 0.460 0.000
E27.5 Adrenomedullary hyperfunction
0.540 0.460 0.000
E27.0 Other adrenocortical overactivity
0.540 0.460 0.000
W25 Contact with sharp glass
0.539 0.461 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.539 0.461 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.539 0.461 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.539 0.461 0.000
M65.3 Trigger finger
0.538 0.461 0.000
X19 Contact with other and unspecified heat and hot substances
0.538 0.462 0.000
J64 Unspecified pneumoconiosis
0.537 0.463 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.537 0.463 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.536 0.463 0.000
M67.4 Ganglion
0.535 0.464 0.000
M40 Kyphosis and lordosis
0.535 0.465 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.535 0.465 0.000
W64 Exposure to other and unspecified animate mechanical forces
0.535 0.465 0.000
W59 Bitten or crushed by other reptiles
0.535 0.465 0.000
W58 Bitten or struck by crocodile or alligator
0.535 0.465 0.000
W56 Contact with marine animal
0.535 0.465 0.000
W54 Bitten or struck by dog
0.535 0.465 0.000
W53 Bitten by rat
0.535 0.465 0.000
W52 Crushed, pushed and stepped on by crowd or human stampede
0.535 0.465 0.000
M22.8 Other disorders of patella
0.535 0.465 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.534 0.465 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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