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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs59735097
log Bayes Factor = 7.95782
Chromosome 2   position 70,398,587  (GRCh37) Explore rs59735097 on Ensembl!
Variant rs59735097 is part of Cluster X0160

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
M13 Other arthritis
0.994 0.006 0.000
M13.9 Arthritis, unspecified
0.992 0.008 0.000
M23 Internal derangement of knee
0.982 0.018 0.000
M65-M68 Disorders of synovium and tendon
0.981 0.019 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.979 0.021 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.977 0.023 0.000
M67 Other disorders of synovium and tendon
0.975 0.025 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.972 0.028 0.000
M25 Other joint disorders, not elsewhere classified
0.972 0.028 0.000
M91-M94 Chondropathies
0.967 0.033 0.000
M86-M90 Other osteopathies
0.967 0.033 0.000
M70-M79 Other soft tissue disorders
0.965 0.035 0.000
M50-M54 Other dorsopathies
0.964 0.036 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.964 0.036 0.000
M67.8 Other specified disorders of synovium and tendon
0.962 0.038 0.000
# Top node
0.962 0.038 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.961 0.039 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.960 0.040 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.960 0.040 0.000
O26.8 Other specified pregnancy-related conditions
0.959 0.041 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.955 0.045 0.000
M22 Disorders of patella
0.954 0.046 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.951 0.049 0.000
M51 Other intervertebral disk disorders
0.949 0.051 0.000
M45-M49 Spondylopathies
0.947 0.053 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.942 0.058 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.935 0.065 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.932 0.068 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.928 0.072 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.923 0.077 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.922 0.078 0.000
L60-L75 Disorders of skin appendages
0.918 0.082 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.917 0.083 0.000
G57 Mononeuropathies of lower limb
0.915 0.085 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.914 0.086 0.000
M89 Other disorders of bone
0.908 0.092 0.000
M79.8 Other specified soft tissue disorders
0.903 0.097 0.000
M25.7 Osteophyte
0.900 0.100 0.000
M13.98 Arthritis, unspecified (Other)
0.898 0.102 0.000
M71 Other bursopathies
0.896 0.104 0.000
O85-O92 Complications predominantly related to the puerperium
0.896 0.104 0.000
M23.8 Other internal derangements of knee
0.896 0.104 0.000
M51.2 Other specified intervertebral disk displacement
0.894 0.106 0.000
G82 Paraplegia and tetraplegia
0.893 0.107 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.887 0.113 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.882 0.118 0.000
M25.4 Effusion of joint
0.882 0.118 0.000
M79.7 Fibromyalgia
0.882 0.118 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.881 0.119 0.000
M93 Other osteochondropathies
0.879 0.121 0.000
Q50-Q56 Congenital malformations of genital organs
0.879 0.121 0.000
G57.6 Lesion of plantar nerve
0.877 0.123 0.000
M94 Other disorders of cartilage
0.876 0.124 0.000
G54 Nerve root and plexus disorders
0.875 0.125 0.000
M46 Other inflammatory spondylopathies
0.872 0.128 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.871 0.129 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.869 0.131 0.000
L71 Rosacea
0.869 0.131 0.000
M60-M63 Disorders of muscles
0.868 0.132 0.000
M79.79 Fibromyalgia (Site unspecified)
0.864 0.136 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.861 0.139 0.000
M25.0 Haemarthrosis
0.859 0.141 0.000
Chapter XX External causes of morbidity and mortality
0.857 0.143 0.000
M10 Gout
0.851 0.149 0.000
M89.9 Disorder of bone, unspecified
0.851 0.149 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.851 0.149 0.000
M22.8 Other disorders of patella
0.849 0.151 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.844 0.156 0.000
M13.93 Arthritis, unspecified (Forearm)
0.843 0.157 0.000
L71.9 Rosacea, unspecified
0.839 0.161 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.839 0.161 0.000
Q60-Q64 Congenital malformations of the urinary system
0.837 0.163 0.000
M30 Polyarteritis nodosa and related conditions
0.836 0.164 0.000
M51.4 Schmorl's nodes
0.835 0.165 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.833 0.167 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.832 0.168 0.000
M77 Other enthesopathies
0.826 0.174 0.000
M86 Osteomyelitis
0.826 0.174 0.000
L72.0 Epidermal cyst
0.825 0.175 0.000
M45 Ankylosing spondylitis
0.824 0.176 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.822 0.178 0.000
O21 Excessive vomiting in pregnancy
0.821 0.179 0.000
M93.9 Osteochondropathy, unspecified
0.817 0.183 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.817 0.183 0.000
M22.3 Other derangements of patella
0.816 0.184 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.815 0.185 0.000
G52 Disorders of other cranial nerves
0.811 0.189 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.809 0.191 0.000
O32.2 Maternal care for transverse and oblique lie
0.808 0.192 0.000
G54.9 Nerve root and plexus disorder, unspecified
0.806 0.194 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.806 0.194 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.806 0.194 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.805 0.195 0.000
M94.8 Other specified disorders of cartilage
0.803 0.197 0.000
V80-V89 Other land transport accidents
0.802 0.198 0.000
M23.4 Loose body in knee
0.801 0.199 0.000
G82.5 Tetraplegia, unspecified
0.799 0.201 0.000
G03 Meningitis due to other and unspecified causes
0.798 0.202 0.000
M25.74 Osteophyte (Hand)
0.798 0.202 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.797 0.203 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.792 0.208 0.000
M15-M19 Arthrosis
0.792 0.208 0.000
M00-M03 Infectious arthropathies
0.792 0.208 0.000
M25.76 Osteophyte (Lower leg)
0.792 0.208 0.000
G80 Infantile cerebral palsy
0.791 0.209 0.000
M25.46 Effusion of joint (Lower leg)
0.789 0.211 0.000
O24 Diabetes mellitus in pregnancy
0.789 0.211 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.787 0.213 0.000
M25.9 Joint disorder, unspecified
0.786 0.214 0.000
M71.3 Other bursal cyst
0.784 0.216 0.000
M62 Other disorders of muscle
0.783 0.216 0.000
M14 Arthropathies in other diseases classified elsewhere
0.782 0.218 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.782 0.218 0.000
Q00-Q07 Congenital malformations of the nervous system
0.781 0.219 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.779 0.221 0.000
M87 Osteonecrosis
0.778 0.222 0.000
M25.06 Haemarthrosis (Lower leg)
0.778 0.222 0.000
M22.2 Patellofemoral disorders
0.776 0.224 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.775 0.225 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.775 0.225 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.774 0.226 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.773 0.227 0.000
M13.0 Polyarthritis, unspecified
0.772 0.228 0.000
M12 Other specific arthropathies
0.772 0.228 0.000
O32.1 Maternal care for breech presentation
0.771 0.229 0.000
M67.0 Short Achilles tendon (acquired)
0.770 0.230 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.768 0.232 0.000
O41 Other disorders of amniotic fluid and membranes
0.767 0.233 0.000
M25.71 Osteophyte (Shoulder region)
0.766 0.234 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.765 0.235 0.000
G82.4 Spastic tetraplegia
0.765 0.235 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.764 0.236 0.000
M25.78 Osteophyte (Other)
0.762 0.238 0.000
W00-W19 Falls
0.762 0.238 0.000
V40-V49 Car occupant injured in transport accident
0.761 0.239 0.000
M19 Other arthrosis
0.758 0.242 0.000
Q61 Cystic kidney disease
0.753 0.247 0.000
M13.8 Other specified arthritis
0.751 0.249 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.749 0.251 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.749 0.251 0.000
M76 Enthesopathies of lower limb, excluding foot
0.748 0.252 0.000
O46.9 Antepartum haemorrhage, unspecified
0.747 0.253 0.000
G90-G99 Other disorders of the nervous system
0.747 0.253 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.746 0.254 0.000
O26.0 Excessive weight gain in pregnancy
0.744 0.255 0.000
M53 Other dorsopathies, not elsewhere classified
0.742 0.258 0.000
M92 Other juvenile osteochondrosis
0.741 0.259 0.000
Q55 Other congenital malformations of male genital organs
0.741 0.259 0.000
M67.4 Ganglion
0.740 0.260 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.740 0.260 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.739 0.261 0.000
G50 Disorders of trigeminal nerve
0.738 0.262 0.000
O00-O08 Pregnancy with abortive outcome
0.738 0.262 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.737 0.263 0.000
O26.2 Pregnancy care of habitual aborter
0.737 0.263 0.000
O21.9 Vomiting of pregnancy, unspecified
0.736 0.264 0.000
G82.2 Paraplegia, unspecified
0.735 0.264 0.000
O32.3 Maternal care for face, brow and chin presentation
0.734 0.266 0.000
M51.8 Other specified intervertebral disk disorders
0.733 0.267 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.732 0.268 0.000
M25.8 Other specified joint disorders
0.731 0.269 0.000
M94.86 Other specified disorders of cartilage (Lower leg)
0.731 0.269 0.000
M77.9 Enthesopathy, unspecified
0.730 0.270 0.000
M66 Spontaneous rupture of synovium and tendon
0.729 0.271 0.000
M19.0 Primary arthrosis of other joints
0.728 0.272 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.728 0.272 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.728 0.272 0.000
O87 Venous complications in the puerperium
0.727 0.273 0.000
M49 Spondylopathies in diseases classified elsewhere
0.727 0.273 0.000
G58 Other mononeuropathies
0.727 0.273 0.000
M50 Cervical disk disorders
0.726 0.274 0.000
M10.0 Idiopathic gout
0.725 0.275 0.000
M89.8 Other specified disorders of bone
0.725 0.275 0.000
V89.9 Person injured in unspecified vehicle accident
0.725 0.275 0.000
M67.1 Other contracture of tendon (sheath)
0.724 0.276 0.000
M89.98 Disorder of bone, unspecified (Other)
0.722 0.278 0.000
L63 Alopecia areata
0.719 0.281 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.719 0.281 0.000
M89.3 Hypertrophy of bone
0.717 0.283 0.000
M05 Seropositive rheumatoid arthritis
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
M13.1 Monoarthritis, not elsewhere classified
0.712 0.287 0.000
M22.4 Chondromalacia patellae
0.712 0.288 0.000
G62 Other polyneuropathies
0.712 0.288 0.000
G53.0 Postzoster neuralgia
0.712 0.288 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.711 0.289 0.000
M62.8 Other specified disorders of muscle
0.710 0.290 0.000
O85 Puerperal sepsis
0.709 0.290 0.000
L50-L54 Urticaria and erythema
0.707 0.293 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.706 0.293 0.000
M86.9 Osteomyelitis, unspecified
0.706 0.294 0.000
O45 Premature separation of placenta [abruptio placentae]
0.706 0.294 0.000
Q51 Congenital malformations of uterus and cervix
0.705 0.295 0.000
Q66 Congenital deformities of feet
0.705 0.295 0.000
G83 Other paralytic syndromes
0.705 0.295 0.000
M71.1 Other infective bursitis
0.705 0.295 0.000
M40-M43 Deforming dorsopathies
0.705 0.295 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.704 0.296 0.000
M34 Systemic sclerosis
0.703 0.297 0.000
M30.0 Polyarteritis nodosa
0.703 0.297 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.702 0.298 0.000
X50-X57 Overexertion, travel and privation
0.702 0.298 0.000
M32 Systemic lupus erythematosus
0.700 0.300 0.000
Q54 Hypospadias
0.700 0.300 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.700 0.300 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.699 0.301 0.000
M67.3 Transient synovitis
0.699 0.301 0.000
G57.5 Tarsal tunnel syndrome
0.699 0.301 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.697 0.303 0.000
O90 Complications of the puerperium, not elsewhere classified
0.697 0.303 0.000
M25.2 Flail joint
0.697 0.303 0.000
M25.1 Fistula of joint
0.697 0.303 0.000
M79.88 Other specified soft tissue disorders (Other)
0.696 0.303 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.696 0.304 0.000
M24 Other specific joint derangements
0.696 0.304 0.000
G03.9 Meningitis, unspecified
0.695 0.305 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.694 0.306 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.694 0.306 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.694 0.306 0.000
M23.1 Discoid meniscus (congenital)
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.693 0.307 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.693 0.307 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.692 0.308 0.000
G06.0 Intracranial abscess and granuloma
0.692 0.308 0.000
O22 Venous complications in pregnancy
0.692 0.308 0.000
Q53 Undescended testicle
0.690 0.310 0.000
O89 Complications of anaesthesia during the puerperium
0.690 0.310 0.000
M25.47 Effusion of joint (Ankle and foot)
0.689 0.310 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.689 0.311 0.000
O29 Complications of anaesthesia during pregnancy
0.689 0.311 0.000
O28 Abnormal findings on antenatal screening of mother
0.689 0.311 0.000
O25 Malnutrition in pregnancy
0.689 0.311 0.000
W18 Other fall on same level
0.689 0.311 0.000
O26.5 Maternal hypotension syndrome
0.688 0.311 0.000
O26.4 Herpes gestationis
0.688 0.311 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.688 0.311 0.000
O26.1 Low weight gain in pregnancy
0.688 0.311 0.000
M48 Other spondylopathies
0.688 0.312 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.687 0.313 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.687 0.313 0.000
Q78 Other osteochondrodysplasias
0.686 0.314 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.686 0.314 0.000
M51.9 Intervertebral disk disorder, unspecified
0.686 0.314 0.000
G51 Facial nerve disorders
0.686 0.314 0.000
Q05 Spina bifida
0.685 0.315 0.000
Q24 Other congenital malformations of heart
0.684 0.316 0.000
M22.1 Recurrent subluxation of patella
0.684 0.316 0.000
M22.9 Disorder of patella, unspecified
0.684 0.316 0.000
M22.0 Recurrent dislocation of patella
0.684 0.316 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.683 0.317 0.000
M90 Osteopathies in diseases classified elsewhere
0.683 0.317 0.000
Q35-Q37 Cleft lip and cleft palate
0.682 0.318 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.682 0.318 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.681 0.319 0.000
M51.3 Other specified intervertebral disk degeneration
0.680 0.320 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.680 0.320 0.000
G61 Inflammatory polyneuropathy
0.680 0.320 0.000
M25.43 Effusion of joint (Forearm)
0.678 0.322 0.000
G56 Mononeuropathies of upper limb
0.677 0.323 0.000
G52.9 Cranial nerve disorder, unspecified
0.677 0.323 0.000
M50.0 Cervical disk disorder with myelopathy
0.677 0.323 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.676 0.324 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.676 0.324 0.000
M79.9 Soft tissue disorder, unspecified
0.675 0.324 0.000
M20 Acquired deformities of fingers and toes
0.675 0.325 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.674 0.326 0.000
M87.9 Osteonecrosis, unspecified
0.674 0.326 0.000
G54.4 Lumbosacral root disorders, not elsewhere classified
0.674 0.326 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.674 0.326 0.000
G80.9 Infantile cerebral palsy, unspecified
0.673 0.327 0.000
L10-L14 Bullous disorders
0.673 0.327 0.000
M46.4 Discitis, unspecified
0.672 0.328 0.000
G82.1 Spastic paraplegia
0.671 0.329 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.669 0.331 0.000
O30 Multiple gestation
0.669 0.331 0.000
M71.34 Other bursal cyst (Hand)
0.669 0.331 0.000
M94.2 Chondromalacia
0.667 0.333 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.665 0.335 0.000
M88 Paget's disease of bone [osteitis deformans]
0.663 0.337 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.663 0.337 0.000
Y00-Y09 Assault
0.662 0.337 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.662 0.337 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.662 0.337 0.000
M23.9 Internal derangement of knee, unspecified
0.662 0.338 0.000
M77.4 Metatarsalgia
0.661 0.339 0.000
M79.3 Panniculitis, unspecified
0.661 0.339 0.000
O86 Other puerperal infections
0.661 0.339 0.000
L75 Apocrine sweat disorders
0.658 0.342 0.000
L74 Eccrine sweat disorders
0.658 0.342 0.000
L68 Hypertrichosis
0.658 0.342 0.000
L67 Hair colour and hair shaft abnormalities
0.658 0.342 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.658 0.342 0.000
L64 Androgenic alopecia
0.658 0.342 0.000
L62 Nail disorders in diseases classified elsewhere
0.658 0.342 0.000
L65 Other nonscarring hair loss
0.657 0.343 0.000
M25.3 Other instability of joint
0.656 0.344 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.656 0.344 0.000
G57.4 Lesion of medial popliteal nerve
0.656 0.344 0.000
G57.2 Lesion of femoral nerve
0.656 0.344 0.000
G57.0 Lesion of sciatic nerve
0.656 0.344 0.000
O40 Polyhydramnios
0.656 0.344 0.000
L72.2 Steatocystoma multiplex
0.655 0.345 0.000
V95-V97 Air and space transport accidents
0.654 0.346 0.000
W06 Fall involving bed
0.653 0.347 0.000
M10.9 Gout, unspecified
0.653 0.347 0.000
G57.8 Other mononeuropathies of lower limb
0.652 0.348 0.000
Q61.3 Polycystic kidney, unspecified
0.651 0.349 0.000
Q61.2 Polycystic kidney, adult type
0.651 0.349 0.000
M89.6 Osteopathy after poliomyelitis
0.651 0.349 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.651 0.349 0.000
M89.2 Other disorders of bone development and growth
0.651 0.349 0.000
M89.1 Epiphyseal arrest
0.651 0.349 0.000
Q63 Other congenital malformations of kidney
0.650 0.350 0.000
O33 Maternal care for known or suspected disproportion
0.649 0.351 0.000
M33 Dermatopolymyositis
0.649 0.351 0.000
M19.1 Posttraumatic arthrosis of other joints
0.649 0.351 0.000
O34.1 Maternal care for tumour of corpus uteri
0.648 0.352 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.647 0.353 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.647 0.353 0.000
M25.79 Osteophyte (Site unspecified)
0.645 0.355 0.000
M25.73 Osteophyte (Forearm)
0.645 0.355 0.000
M25.70 Osteophyte (Multiple sites)
0.645 0.355 0.000
W18.3 Sports and athletics area
0.645 0.355 0.000
G00 Bacterial meningitis, not elsewhere classified
0.645 0.355 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.643 0.356 0.000
M79.0 Rheumatism, unspecified
0.643 0.357 0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg
0.643 0.357 0.000
M71.9 Bursopathy, unspecified
0.643 0.357 0.000
M71.8 Other specified bursopathies
0.643 0.357 0.000
M71.5 Other bursitis, not elsewhere classified
0.643 0.357 0.000
M71.4 Calcium deposit in bursa
0.643 0.357 0.000
M71.0 Abscess of bursa
0.643 0.357 0.000
O91 Infections of breast associated with childbirth
0.643 0.357 0.000
O88 Obstetric embolism
0.643 0.357 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.643 0.357 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.643 0.357 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.643 0.357 0.000
M00 Pyogenic arthritis
0.642 0.358 0.000
Q55.2 Other congenital malformations of testis and scrotum
0.642 0.358 0.000
M79.2 Neuralgia and neuritis, unspecified
0.642 0.358 0.000
M25.97 Joint disorder, unspecified (Ankle and foot)
0.642 0.358 0.000
G62.9 Polyneuropathy, unspecified
0.641 0.359 0.000
G95 Other diseases of spinal cord
0.641 0.359 0.000
G82.3 Flaccid tetraplegia
0.640 0.360 0.000
G82.0 Flaccid paraplegia
0.640 0.360 0.000
O32.4 Maternal care for high head at term
0.639 0.361 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.639 0.361 0.000
L73 Other follicular disorders
0.639 0.361 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.638 0.362 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.638 0.362 0.000
M20.5 Other deformities of toe(s) (acquired)
0.638 0.362 0.000
M94.88 Other specified disorders of cartilage (Other)
0.637 0.363 0.000
W75-W84 Other accidental threats to breathing
0.637 0.363 0.000
M80-M85 Disorders of bone density and structure
0.636 0.364 0.000
M23.41 Loose body in knee-Ant lig/hrn men
0.636 0.364 0.000
O31 Complications specific to multiple gestation
0.636 0.364 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.634 0.366 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.634 0.366 0.000
Y10-Y34 Event of undetermined intent
0.633 0.367 0.000
M25.49 Effusion of joint (Site unspecified)
0.632 0.367 0.000
M25.48 Effusion of joint (Other)
0.632 0.367 0.000
M25.44 Effusion of joint (Hand)
0.632 0.367 0.000
M25.42 Effusion of joint (Upper arm)
0.632 0.367 0.000
M25.41 Effusion of joint (Shoulder region)
0.632 0.367 0.000
M79.78 Fibromyalgia (Other)
0.632 0.368 0.000
M79.77 Fibromyalgia (Ankle and foot)
0.632 0.368 0.000
M79.76 Fibromyalgia (Lower leg)
0.632 0.368 0.000
M79.75 Fibromyalgia (Pelvic region and thigh)
0.632 0.368 0.000
M79.74 Fibromyalgia (Hand)
0.632 0.368 0.000
M79.73 Fibromyalgia (Forearm)
0.632 0.368 0.000
M79.72 Fibromyalgia (Upper arm)
0.632 0.368 0.000
M79.71 Fibromyalgia (Shoulder region)
0.632 0.368 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.632 0.368 0.000
X60-X84 Intentional self-harm
0.631 0.369 0.000
M93.8 Other specified osteochondropathies
0.631 0.369 0.000
M93.2 Osteochondritis dissecans
0.631 0.369 0.000
M93.1 Kienbock's disease of adults
0.631 0.369 0.000
M93.0 Slipped upper femoral epiphysis (nontraumatic)
0.631 0.369 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.631 0.369 0.000
Q56 Indeterminate sex and pseudohermaphroditism
0.630 0.369 0.000
Q52 Other congenital malformations of female genitalia
0.630 0.369 0.000
G60 Hereditary and idiopathic neuropathy
0.630 0.370 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.630 0.370 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.629 0.371 0.000
M86.8 Other osteomyelitis
0.629 0.371 0.000
M71.38 Other bursal cyst (Other)
0.629 0.371 0.000
M14.6 Neuropathic arthropathy
0.629 0.371 0.000
M10.09 Idiopathic gout (Site unspecified)
0.629 0.371 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.629 0.371 0.000
M94.3 Chondrolysis
0.628 0.372 0.000
M94.1 Relapsing polychondritis
0.628 0.372 0.000
M94.0 Chondrocostal junction syndrome [Tietze]
0.628 0.372 0.000
O20 Haemorrhage in early pregnancy
0.627 0.373 0.000
G54.8 Other nerve root and plexus disorders
0.627 0.373 0.000
G54.7 Phantom limb syndrome without pain
0.627 0.373 0.000
G54.6 Phantom limb syndrome with pain
0.627 0.373 0.000
G54.5 Neuralgic amyotrophy
0.627 0.373 0.000
G54.3 Thoracic root disorders, not elsewhere classified
0.627 0.373 0.000
G54.2 Cervical root disorders, not elsewhere classified
0.627 0.373 0.000
G54.1 Lumbosacral plexus disorders
0.627 0.373 0.000
M11 Other crystal arthropathies
0.627 0.373 0.000
Q76 Congenital malformations of spine and bony thorax
0.626 0.374 0.000
O92.2 Other and unspecified disorders of breast associated with childbirth
0.626 0.374 0.000
M23.0 Cystic meniscus
0.626 0.374 0.000
M46.8 Other specified inflammatory spondylopathies
0.625 0.375 0.000
M46.5 Other infective spondylopathies
0.625 0.375 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.625 0.375 0.000
M46.2 Osteomyelitis of vertebra
0.625 0.375 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.625 0.375 0.000
M46.0 Spinal enthesopathy
0.625 0.375 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.625 0.375 0.000
L70 Acne
0.625 0.375 0.000
M25.40 Effusion of joint (Multiple sites)
0.624 0.376 0.000
O32.6 Maternal care for compound presentation
0.624 0.376 0.000
M77.91 Enthesopathy, unspecified (Shoulder region)
0.624 0.376 0.000
L71.8 Other rosacea
0.623 0.377 0.000
L71.0 Perioral dermatitis
0.623 0.377 0.000
M07 Psoriatic and enteropathic arthropathies
0.622 0.377 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.622 0.378 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.622 0.378 0.000
M61 Calcification and ossification of muscle
0.622 0.378 0.000
M23.5 Chronic instability of knee
0.621 0.378 0.000
W05 Fall involving wheelchair
0.621 0.379 0.000
M77.5 Other enthesopathy of foot
0.619 0.381 0.000
Q66.8 Other congenital deformities of feet
0.619 0.381 0.000
G06.1 Intraspinal abscess and granuloma
0.618 0.382 0.000
M24.0 Loose body in joint
0.617 0.382 0.000
M76.8 Other enthesopathies of lower limb, excluding foot
0.617 0.383 0.000
Q25 Congenital malformations of great arteries
0.617 0.383 0.000
Q74 Other congenital malformations of limb(s)
0.617 0.383 0.000
Q05.9 Spina bifida, unspecified
0.617 0.383 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.617 0.383 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.616 0.384 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.616 0.384 0.000
G06.2 Extradural and subdural abscess, unspecified
0.616 0.384 0.000
O21.2 Late vomiting of pregnancy
0.616 0.384 0.000
M25.09 Haemarthrosis (Site unspecified)
0.616 0.384 0.000
M25.08 Haemarthrosis (Other)
0.616 0.384 0.000
M25.07 Haemarthrosis (Ankle and foot)
0.616 0.384 0.000
M25.05 Haemarthrosis (Pelvic region and thigh)
0.616 0.384 0.000
M25.04 Haemarthrosis (Hand)
0.616 0.384 0.000
M25.03 Haemarthrosis (Forearm)
0.616 0.384 0.000
M25.02 Haemarthrosis (Upper arm)
0.616 0.384 0.000
M25.01 Haemarthrosis (Shoulder region)
0.616 0.384 0.000
M25.00 Haemarthrosis (Multiple sites)
0.616 0.384 0.000
M94.9 Disorder of cartilage, unspecified
0.615 0.385 0.000
Y35-Y36 Legal intervention and operations of war
0.615 0.385 0.000
X85-X99 Assault
0.615 0.385 0.000
X30-X39 Exposure to forces of nature
0.615 0.385 0.000
X00-X09 Exposure to smoke, fire and flames
0.615 0.385 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.615 0.385 0.000
W65-W74 Accidental drowning and submersion
0.615 0.385 0.000
V98-V99 Other and unspecified transport accidents
0.615 0.385 0.000
V90-V94 Water transport accidents
0.615 0.385 0.000
V70-V79 Bus occupant injured in transport accident
0.615 0.385 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.615 0.385 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.615 0.385 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.615 0.385 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.614 0.386 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.614 0.386 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.613 0.387 0.000
W50-W64 Exposure to animate mechanical forces
0.613 0.387 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.613 0.387 0.000
M89.5 Osteolysis
0.612 0.388 0.000
G57.1 Meralgia paraesthetica
0.612 0.388 0.000
M41 Scoliosis
0.611 0.389 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.611 0.389 0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic
0.611 0.389 0.000
M10.4 Other secondary gout
0.610 0.390 0.000
M10.3 Gout due to impairment of renal function
0.610 0.390 0.000
M10.2 Drug-induced gout
0.610 0.390 0.000
M10.1 Lead-induced gout
0.610 0.390 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.610 0.390 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.610 0.390 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.610 0.390 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.610 0.390 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.610 0.390 0.000
G64 Other disorders of peripheral nervous system
0.610 0.390 0.000
G50.9 Disorder of trigeminal nerve, unspecified
0.609 0.391 0.000
G56.0 Carpal tunnel syndrome
0.609 0.391 0.000
M50.1 Cervical disk disorder with radiculopathy
0.609 0.391 0.000
G12 Spinal muscular atrophy and related syndromes
0.609 0.391 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.609 0.391 0.000
M23.49 Loose body in knee-Unspec lig/men
0.609 0.391 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.609 0.391 0.000
Q24.8 Other specified congenital malformations of heart
0.607 0.392 0.000
G57.3 Lesion of lateral popliteal nerve
0.607 0.393 0.000
G52.8 Disorders of other specified cranial nerves
0.607 0.393 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.606 0.394 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.605 0.395 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.604 0.396 0.000
G80.2 Infantile hemiplegia
0.603 0.397 0.000
M20.2 Hallux rigidus
0.603 0.397 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.602 0.398 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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