TreeWAS – Variant ID: rs6124878

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
O60-O75 Complications of labour and delivery	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000
# Top node	0.992	0.008
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.991	0.009
Chapter V Mental and behavioural disorders	0.991	0.009
O75 Other complications of labour and delivery, not elsewhere classified	0.987	0.013
Chapter IX Diseases of the circulatory system	0.986	0.014
F30-F39 Mood [affective] disorders	0.983	0.017
F31 Bipolar affective disorder	0.983	0.017
I10-I15 Hypertensive diseases	0.976	0.024
O72 Postpartum haemorrhage	0.976	0.024
F00-F09 Organic, including symptomatic, mental disorders	0.970	0.030
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.970	0.030
F31.9 Bipolar affective disorder, unspecified	0.967	0.033
O64 Obstructed labour due to malposition and malpresentation of foetus	0.960	0.040
O85-O92 Complications predominantly related to the puerperium	0.956	0.044
Chapter I Certain infectious and parasitic diseases	0.944	0.056
B95-B98 Bacterial, viral and other infectious agents	0.942	0.058
I05-I09 Chronic rheumatic heart diseases	0.932	0.068
I15 Secondary hypertension	0.931	0.069
S40-S49 Injuries to the shoulder and upper arm	0.931	0.069
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.930	0.070
O75.8 Other specified complications of labour and delivery	0.929	0.071
I60-I69 Cerebrovascular diseases	0.921	0.079
S20-S29 Injuries to the thorax	0.921	0.079
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.921	0.079
F03 Unspecified dementia	0.920	0.080
O48 Prolonged pregnancy	0.914	0.086
O86 Other puerperal infections	0.908	0.092
O72.0 Third-stage haemorrhage	0.906	0.094
O30 Multiple gestation	0.902	0.098
O64.1 Obstructed labour due to breech presentation	0.897	0.103
O75.7 Vaginal delivery following previous Caesarean section	0.895	0.105
T20-T25 Burns and corrosions of external body surface, specified by site	0.893	0.107
O72.2 Delayed and secondary postpartum haemorrhage	0.883	0.117
I15.1 Hypertension secondary to other renal disorders	0.873	0.127
Chapter XXII Codes for special purposes	0.873	0.127
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.872	0.128
I10 Essential (primary) hypertension	0.870	0.130
Chapter VIII Diseases of the ear and mastoid process	0.868	0.132
O41 Other disorders of amniotic fluid and membranes	0.867	0.133
I05 Rheumatic mitral valve diseases	0.867	0.133
O42 Premature rupture of membranes	0.866	0.134
S22 Fracture of rib(s), sternum and thoracic spine	0.859	0.141
Chapter XX External causes of morbidity and mortality	0.859	0.141
I11 Hypertensive heart disease	0.857	0.143
S80-S89 Injuries to the knee and lower leg	0.857	0.143
I67 Other cerebrovascular diseases	0.856	0.144
O86.0 Infection of obstetric surgical wound	0.854	0.146
O71 Other obstetric trauma	0.850	0.150
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.848	0.152
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.843	0.157
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.839	0.161
O30.0 Twin pregnancy	0.839	0.161
S42 Fracture of shoulder and upper arm	0.837	0.163
S49 Other and unspecified injuries of shoulder and upper arm	0.834	0.166
O32 Maternal care for known or suspected malpresentation of foetus	0.832	0.168
S82 Fracture of lower leg, including ankle	0.827	0.173
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.827	0.173
B97 Viral agents as the cause of diseases classified to other chapters	0.825	0.175
S00-S09 Injuries to the head	0.825	0.175
H90-H95 Other disorders of ear	0.823	0.177
O69 Labour and delivery complicated by umbilical cord complications	0.822	0.178
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.820	0.180
I05.0 Mitral stenosis	0.820	0.180
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.819	0.181
F05 Delirium, not induced by alcohol and other psychoactive substances	0.817	0.183
I69 Sequelae of cerebrovascular disease	0.816	0.184
O73 Retained placenta and membranes, without haemorrhage	0.814	0.186
F80-F89 Disorders of psychological development	0.813	0.187
T15-T19 Effects of foreign body entering through natural orifice	0.809	0.191
F02 Dementia in other diseases classified elsewhere	0.806	0.194
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.806	0.194
F31.7 Bipolar affective disorder, currently in remission	0.803	0.197
F00 Dementia in Alzheimer's disease	0.802	0.198
O63 Long labour	0.802	0.198
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.802	0.198
S22.4 Multiple fractures of ribs	0.801	0.199
I27 Other pulmonary heart diseases	0.799	0.201
I61 Intracerebral haemorrhage	0.798	0.202
A15-A19 Tuberculosis	0.798	0.202
F31.0 Bipolar affective disorder, current episode hypomanic	0.796	0.204
O75.2 Pyrexia during labour, not elsewhere classified	0.794	0.206
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.793	0.207
O75.0 Maternal distress during labour and delivery	0.792	0.208
U88 Agent resistant to multiple antibiotics	0.790	0.210
O66 Other obstructed labour	0.789	0.211
S05 Injury of eye and orbit	0.788	0.212
T20 Burn and corrosion of head and neck	0.787	0.213
S82.1 Fracture of upper end of tibia	0.787	0.213
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.787	0.213
I15.9 Seconday hypertension, unspecified	0.785	0.215
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.783	0.217
F60-F69 Disorders of adult personality and behaviour	0.783	0.217
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.783	0.217
I64 Stroke, not specified as haemorrhage or infarction	0.781	0.219
S27 Injury of other and unspecified intrathoracic organs	0.778	0.222
O41.8 Other specified disorders of amniotic fluid and membranes	0.778	0.222
I08 Multiple valve diseases	0.778	0.222
O72.1 Other immediate postpartum haemorrhage	0.774	0.226
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.773	0.227
F39 Unspecified mood [affective] disorder	0.771	0.229
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.765	0.235
S49.9 Unspecified injury of shoulder and upper arm	0.764	0.236
S22.40 Multiple fractures of ribs (closed)	0.759	0.241
V10-V19 Pedal cyclist injured in transport accident	0.759	0.241
S82.10 Fracture of upper end of tibia (closed)	0.758	0.242
I67.9 Cerebrovascular disease, unspecified	0.755	0.245
I27.0 Primary pulmonary hypertension	0.754	0.246
O64.8 Obstructed labour due to other malposition and malpresentation	0.748	0.252
I08.1 Disorders of both mitral and tricuspid valves	0.748	0.252
O35 Maternal care for known or suspected foetal abnormality and damage	0.748	0.252
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.746	0.254
O44 Placenta praevia	0.746	0.254
O34 Maternal care for known or suspected abnormality of pelvic organs	0.746	0.254
S42.1 Fracture of scapula	0.744	0.256
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.743	0.257
O71.5 Other obstetric injury to pelvic organs	0.743	0.257
T66-T78 Other and unspecified effects of external causes	0.741	0.259
I11.9 Hypertensive heart disease without (congestive) heart failure	0.740	0.260
O92 Other disorders of breast and lactation associated with childbirth	0.739	0.261
O68 Labour and delivery complicated by foetal stress [distress]	0.736	0.264
F29 Unspecified nonorganic psychosis	0.734	0.266
O67.9 Intrapartum haemorrhage, unspecified	0.731	0.269
S10-S19 Injuries to the neck	0.729	0.271
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.726	0.274
O43 Placental disorders	0.724	0.276
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.724	0.276
O45 Premature separation of placenta [abruptio placentae]	0.723	0.277
O94-O99 Other obstetric conditions, not elsewhere classified	0.723	0.277
Y43 Primarily systemic agents	0.720	0.280
S82.6 Fracture of lateral malleolus	0.719	0.281
S46 Injury of muscle and tendon at shoulder and upper arm level	0.719	0.281
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.719	0.281
F30 Manic episode	0.718	0.282
S05.1 Contusion of eyeball and orbital tissues	0.718	0.282
S40 Superficial injury of shoulder and upper arm	0.718	0.282
I05.2 Mitral stenosis with insufficiency	0.717	0.283
O90 Complications of the puerperium, not elsewhere classified	0.717	0.283
O74 Complications of anaesthesia during labour and delivery	0.717	0.283
O65 Obstructed labour due to maternal pelvic abnormality	0.717	0.283
O60 Preterm delivery	0.717	0.283
S42.4 Fracture of lower end of humerus	0.717	0.283
O16 Unspecified maternal hypertension	0.716	0.284
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.715	0.285
S21 Open wound of thorax	0.715	0.285
I67.8 Other specified cerebrovascular diseases	0.715	0.285
I12 Hypertensive renal disease	0.713	0.287
S22.0 Fracture of thoracic vertebra	0.713	0.287
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.712	0.287
B25-B34 Other viral diseases	0.712	0.288
H92 Otalgia and effusion of ear	0.712	0.288
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.712	0.288
Chapter XVI Certain conditions originating in the perinatal period	0.711	0.289
H93 Other disorders of ear, not elsewhere classified	0.711	0.289
O33 Maternal care for known or suspected disproportion	0.710	0.290
O31 Complications specific to multiple gestation	0.710	0.290
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.710	0.290
F70-F79 Mental retardation	0.710	0.290
S00 Superficial injury of head	0.709	0.291
O87 Venous complications in the puerperium	0.709	0.291
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.708	0.292
O75.9 Complication of labour and delivery, unspecified	0.708	0.292
O75.5 Delayed delivery after artificial rupture of membranes	0.708	0.292
O75.4 Other complications of obstetric surgery and procedures	0.708	0.292
O75.3 Other infection during labour	0.708	0.292
O75.1 Shock during or following labour and delivery	0.708	0.292
X58-X59 Accidental exposure to other and unspecified factors	0.708	0.292
I00-I02 Acute rheumatic fever	0.707	0.293
B99-B99 Other infectious diseases	0.707	0.293
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.707	0.293
F38 Other mood [affective] disorders	0.705	0.295
F34 Persistent mood [affective] disorders	0.705	0.295
O40 Polyhydramnios	0.705	0.295
F31.8 Other bipolar affective disorders	0.705	0.295
F31.6 Bipolar affective disorder, current episode mixed	0.705	0.295
I69.3 Sequelae of cerebral infarction	0.705	0.295
O86.1 Other infection of genital tract following delivery	0.704	0.296
X10-X19 Contact with heat and hot substances	0.704	0.296
O86.4 Pyrexia of unknown origin following delivery	0.704	0.296
V80-V89 Other land transport accidents	0.702	0.298
I13 Hypertensive heart and renal disease	0.700	0.300
O32.1 Maternal care for breech presentation	0.700	0.300
O72.3 Postpartum coagulation defects	0.700	0.300
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.699	0.301
T25 Burn and corrosion of ankle and foot	0.698	0.302
O41.1 Infection of amniotic sac and membranes	0.698	0.302
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.698	0.302
S90-S99 Injuries to the ankle and foot	0.698	0.302
O62 Abnormalities of forces of labour	0.696	0.304
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.696	0.304
F09 Unspecified organic or symptomatic mental disorder	0.696	0.304
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.696	0.304
T33-T35 Frostbite	0.696	0.304
T26-T28 Burns and corrosions confined to eye and internal organs	0.696	0.304
T00-T07 Injuries involving multiple body regions	0.696	0.304
H90 Conductive and sensorineural hearing loss	0.695	0.305
A50-A64 Infections with a predominantly sexual mode of transmission	0.695	0.305
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.690	0.310
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.690	0.310
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.689	0.311
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.688	0.312
O64.5 Obstructed labour due to compound presentation	0.688	0.312
O64.4 Obstructed labour due to shoulder presentation	0.688	0.312
O64.3 Obstructed labour due to brow presentation	0.688	0.312
O64.2 Obstructed labour due to face presentation	0.688	0.312
S42.9 Fracture of shoulder girdle, part unspecified	0.688	0.312
I09 Other rheumatic heart diseases	0.687	0.313
T18 Foreign body in alimentary tract	0.686	0.314
T23 Burn and corrosion of wrist and hand	0.686	0.314
O47 False labour	0.686	0.314
O91 Infections of breast associated with childbirth	0.685	0.314
O89 Complications of anaesthesia during the puerperium	0.685	0.314
O88 Obstetric embolism	0.685	0.314
O85 Puerperal sepsis	0.685	0.314
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.684	0.316
O63.1 Prolonged second stage (of labour)	0.682	0.318
F00.9 Dementia in Alzheimer's disease, unspecified	0.682	0.318
O73.0 Retained placenta, without haemorrhage	0.681	0.319
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.680	0.320
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.679	0.321
V18 Pedal cyclist injured in noncollision transport accident	0.679	0.321
I11.0 Hypertensive heart disease with (congestive) heart failure	0.678	0.322
B85-B89 Pediculosis, acariasis and other infestations	0.677	0.323
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.677	0.323
A75-A79 Rickettsioses	0.677	0.323
A70-A74 Other diseases caused by chlamydiae	0.677	0.323
A65-A69 Other spirochaetal diseases	0.677	0.323
A20-A28 Certain zoonotic bacterial diseases	0.677	0.323
S42.10 Fracture of scapula (closed)	0.677	0.323
W50-W64 Exposure to animate mechanical forces	0.676	0.324
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.675	0.325
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.670	0.330
S20 Superficial injury of thorax	0.669	0.331
I06 Rheumatic aortic valve diseases	0.668	0.332
I15.8 Other secondary hypertension	0.668	0.332
I15.2 Hypertension secondary to endocrine disorders	0.668	0.332
I15.0 Renovascular hypertension	0.668	0.332
S48 Traumatic amputation of shoulder and upper arm	0.667	0.332
S45 Injury of blood vessels at shoulder and upper arm level	0.667	0.332
S44 Injury of nerves at shoulder and upper arm level	0.667	0.332
S47 Crushing injury of shoulder and upper arm	0.667	0.332
S05.8 Other injuries of eye and orbit	0.667	0.333
F81 Specific developmental disorders of scholastic skills	0.667	0.333
B20-B24 Human immunodeficiency virus [HIV] disease	0.665	0.335
Y57 Other and unspecified drugs and medicaments	0.664	0.336
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.664	0.336
Y43.3 Other antineoplastic drugs	0.664	0.336
I61.5 Intracerebral haemorrhage, intraventricular	0.664	0.336
S86 Injury of muscle and tendon at lower leg level	0.663	0.337
O34.1 Maternal care for tumour of corpus uteri	0.661	0.339
B50-B64 Protozoal diseases	0.661	0.339
I68 Cerebrovascular disorders in diseases classified elsewhere	0.661	0.339
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.661	0.339
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.660	0.339
S26 Injury of heart	0.660	0.339
S25 Injury of blood vessels of thorax	0.660	0.339
S24 Injury of nerves and spinal cord at thorax level	0.660	0.339
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.660	0.339
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.659	0.340
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.659	0.341
O69.2 Labour and delivery complicated by other cord entanglement	0.658	0.342
I69.1 Sequelae of intracerebral haemorrhage	0.658	0.342
F05.9 Delirium, unspecified	0.657	0.343
T31 Burns classified according to extent of body surface involved	0.656	0.344
T20.2 Burn of second degree of head and neck	0.655	0.345
I67.1 Cerebral aneurysm, nonruptured	0.653	0.346
S82.5 Fracture of medial malleolus	0.652	0.348
S22.3 Fracture of rib	0.651	0.348
O86.8 Other specified puerperal infections	0.651	0.349
O86.3 Other genito-urinary tract infections following delivery	0.651	0.349
O86.2 Urinary tract infection following delivery	0.651	0.349
O42.9 Premature rupture of membranes, unspecified	0.651	0.349
O61 Failed induction of labour	0.650	0.350
F02.8 Dementia in other specified diseases classified elsewhere	0.650	0.350
I67.2 Cerebral atherosclerosis	0.649	0.351
T79-T79 Certain early complications of trauma	0.649	0.351
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.648	0.352
V20-V29 Motorcycle rider injured in transport accident	0.647	0.353
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.647	0.353
O30.9 Multiple gestation, unspecified	0.647	0.353
O30.8 Other multiple gestation	0.647	0.353
O30.2 Quadruplet pregnancy	0.647	0.353
O30.1 Triplet pregnancy	0.647	0.353
S00.8 Superficial injury of other parts of head	0.646	0.354
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.646	0.354
H90.5 Sensorineural hearing loss, unspecified	0.645	0.355
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.645	0.355
O69.8 Labour and delivery complicated by other cord complications	0.645	0.355
Y44 Agents primarily affecting blood constituents	0.644	0.356
I07 Rheumatic tricuspid valve diseases	0.644	0.356
S70-S79 Injuries to the hip and thigh	0.644	0.356
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.643	0.357
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.643	0.357
T21 Burn and corrosion of trunk	0.642	0.358
S42.7 Multiple fractures of clavicle, scapula and humerus	0.642	0.358
S82.60 Fracture of lateral malleolus (closed)	0.642	0.358
T20.0 Burn of unspecified degree of head and neck	0.640	0.360
F25 Schizoaffective disorders	0.640	0.360
H65-H75 Diseases of middle ear and mastoid	0.639	0.361
S82.7 Multiple fractures of lower leg	0.638	0.362
B15-B19 Viral hepatitis	0.635	0.365
S27.2 Traumatic heamopneumothorax	0.635	0.365
I95-I99 Other and unspecified disorders of the circulatory system	0.635	0.365
S50-S59 Injuries to the elbow and forearm	0.634	0.366
S41 Open wound of shoulder and upper arm	0.631	0.369
F05.1 Delirium superimposed on dementia	0.630	0.370
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.629	0.370
F60 Specific personality disorders	0.629	0.371
Y46 Antiepileptics and anti-Parkinsonism drugs	0.629	0.371
B90-B94 Sequelae of infectious and parasitic diseases	0.628	0.372
F99-F99 Unspecified mental disorder	0.628	0.372
H93.1 Tinnitus	0.628	0.372
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.626	0.374
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.625	0.375
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.625	0.375
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.625	0.375
S22.1 Multiple fractures of thoracic spine	0.625	0.375
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.621	0.378
I05.8 Other mitral valve diseases	0.621	0.378
O42.2 Premature rupture of membranes, labour delayed by therapy	0.621	0.379
Y00-Y09 Assault	0.621	0.379
F05.8 Other delirium	0.620	0.379
H92.0 Otalgia	0.620	0.380
X40-X49 Accidental poisoning by and exposure to noxious substances	0.619	0.381
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.618	0.382
S82.4 Fracture of fibula alone	0.618	0.382
V18.0 Driver injured in nontraffic accident	0.618	0.382
I05.1 Rheumatic mitral insufficiency	0.617	0.383
S22.9 Fracture of bony thorax, part unspecified	0.616	0.384
S22.8 Fracture of other parts of bony thorax	0.616	0.384
Y35-Y36 Legal intervention and operations of war	0.616	0.384
Y10-Y34 Event of undetermined intent	0.616	0.384
X85-X99 Assault	0.616	0.384
X30-X39 Exposure to forces of nature	0.616	0.384
X00-X09 Exposure to smoke, fire and flames	0.616	0.384
W75-W84 Other accidental threats to breathing	0.616	0.384
W65-W74 Accidental drowning and submersion	0.616	0.384
V98-V99 Other and unspecified transport accidents	0.616	0.384
V95-V97 Air and space transport accidents	0.616	0.384
V90-V94 Water transport accidents	0.616	0.384
V70-V79 Bus occupant injured in transport accident	0.616	0.384
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.616	0.384
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.616	0.384
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.616	0.384
V01-V09 Pedestrian injured in transport accident	0.616	0.384
S27.3 Other injuries of lung	0.615	0.384
I27.2 Other secondary pulmonary hypertension	0.615	0.385
O71.8 Other specified obstetric trauma	0.615	0.385
S88 Traumatic amputation of lower leg	0.614	0.386
S87 Crushing injury of lower leg	0.614	0.386
S85 Injury of blood vessels at lower leg level	0.614	0.386
S84 Injury of nerves at lower leg level	0.614	0.386
I67.7 Cerebral arteritis, not elsewhere classified	0.614	0.386
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.614	0.386
I67.5 Moyamoya disease	0.614	0.386
I67.4 Hypertensive encephalopathy	0.614	0.386
I67.3 Progressive vascular leukoencephalopathy	0.614	0.386
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.613	0.386
F80 Specific developmental disorders of speech and language	0.612	0.388
O66.0 Obstructed labour due to shoulder dystocia	0.612	0.388
I62 Other nontraumatic intracranial haemorrhage	0.611	0.389
O32.9 Maternal care for malpresentation of foetus, unspecified	0.611	0.389
O71.9 Obstetric trauma, unspecified	0.609	0.390
O71.7 Obstetric haematoma of pelvis	0.609	0.390
O71.6 Obstetric damage to pelvic joints and ligaments	0.609	0.390
O71.3 Obstetric laceration of cervix	0.609	0.390
O71.2 Postpartum inversion of uterus	0.609	0.390
O71.1 Rupture of uterus during labour	0.609	0.390
O71.0 Rupture of uterus before onset of labour	0.609	0.390
X59 Exposure to unspecified factor	0.609	0.391
S22.00 Fracture of thoracic vertebra (closed)	0.608	0.392
I28 Other diseases of pulmonary vessels	0.608	0.392
F02.3 Dementia in Parkinson's disease	0.608	0.392
F02.0 Dementia in Pick's disease	0.607	0.393
I30-I52 Other forms of heart disease	0.607	0.393
H60-H62 Diseases of external ear	0.605	0.395
O67.8 Other intrapartum haemorrhage	0.604	0.395
O67.0 Intrapartum haemorrhage with coagulation defect	0.604	0.395
O71.4 Obstetric high vaginal laceration alone	0.604	0.396
I51 Complications and ill-defined descriptions of heart disease	0.603	0.397
I51.7 Cardiomegaly	0.601	0.399
S42.8 Fracture of other parts of shoulder and upper arm	0.600	0.400
A80-A89 Viral infections of the central nervous system	0.599	0.401
O32.0 Maternal care for unstable lie	0.598	0.402
S49.8 Other specified injuries of shoulder and upper arm	0.598	0.402
S49.7 Multiple injuries of shoulder and upper arm	0.598	0.402
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.598	0.402
O32.6 Maternal care for compound presentation	0.597	0.403
O32.3 Maternal care for face, brow and chin presentation	0.597	0.403
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.596	0.404
B65-B83 Helminthiases	0.594	0.405
O69.1 Labour and delivery complicated by cord around neck, with compression	0.595	0.405
T20.1 Burn of first degree of head and neck	0.594	0.405
T17 Foreign body in respiratory tract	0.594	0.406
O46 Antepartum haemorrhage, not elsewhere classified	0.594	0.406
S00.5 Superficial injury of lip and oral cavity	0.594	0.406
S42.40 Fracture of lower end of humerus (closed)	0.594	0.406
S82.9 Fracture of lower leg, part unspecified	0.593	0.407
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.591	0.408
B97.5 Reovirus as the cause of diseases classified to other chapters	0.591	0.408
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.591	0.408
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.591	0.408
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.591	0.408
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.591	0.408
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.591	0.408
S08 Traumatic amputation of part of head	0.591	0.409
S07 Crushing injury of head	0.591	0.409
S04 Injury of cranial nerves	0.591	0.409
S03 Dislocation, sprain and strain of joints and ligaments of head	0.591	0.409
H91 Other hearing loss	0.591	0.409
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.590	0.410
H94 Other disorders of ear in diseases classified elsewhere	0.590	0.410
O69.5 Labour and delivery complicated by vascular lesion of cord	0.590	0.410
O69.4 Labour and delivery complicated by vasa praevia	0.590	0.410
O69.3 Labour and delivery complicated by short cord	0.590	0.410
O69.0 Labour and delivery complicated by prolapse of cord	0.590	0.410
O32.8 Maternal care for other malpresentation of foetus	0.589	0.411
I20-I25 Ischaemic heart diseases	0.589	0.411
S89 Other and unspecified injuries of lower leg	0.589	0.411
I67.0 Dissection of cerebral arteries, nonruptured	0.588	0.412
U84 Resistance to other antimicrobial drugs	0.587	0.413
U83 Resistance to other antibiotics	0.587	0.413
U82 Resistance to betalactam antibiotics	0.587	0.413
U85 Resistance to antineoplastic drugs	0.587	0.413
S22.5 Flail chest	0.587	0.413
F05.0 Delirium not superimposed on dementia, so described	0.586	0.414
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.585	0.415
O32.4 Maternal care for high head at term	0.584	0.415
X20-X29 Contact with venomous animals and plants	0.584	0.416
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.584	0.416
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.584	0.416
S27.1 Traumatic haemothorax	0.583	0.416
I27.9 Pulmonary heart disease, unspecified	0.583	0.417
F84 Pervasive developmental disorders	0.583	0.417
F89 Unspecified disorder of psychological development	0.583	0.417
F88 Other disorders of psychological development	0.583	0.417
F83 Mixed specific developmental disorders	0.583	0.417
F82 Specific developmental disorder of motor function	0.583	0.417
F01 Vascular dementia	0.582	0.418
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.581	0.419
O69.9 Labour and delivery complicated by cord complication, unspecified	0.581	0.419
S82.0 Fracture of patella	0.581	0.419
Y49 Psychotropic drugs, not elsewhere classified	0.580	0.420
Chapter VI Diseases of the nervous system	0.580	0.420
T19 Foreign body in genito-urinary tract	0.580	0.420
T15 Foreign body on external eye	0.580	0.420
T16 Foreign body in ear	0.580	0.420
I20 Angina pectoris	0.579	0.421
S46.0 Injury of tendon of the rotator cuff of shoulder	0.579	0.421
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.578	0.422
O44.0 Placenta praevia specified as without haemorrhage	0.578	0.422
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.578	0.422
F02.2 Dementia in Huntington's disease	0.578	0.422
F02.1 Dementia in Creutzfeldt-Jakob disease	0.578	0.422
F28 Other nonorganic psychotic disorders	0.578	0.422
F24 Induced delusional disorder	0.578	0.422
F21 Schizotypal disorder	0.578	0.422
O63.9 Long labour, unspecified	0.576	0.423
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.575	0.425
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.575	0.425
F00.1 Dementia in Alzheimer's disease with late onset	0.575	0.425
F00.0 Dementia in Alzheimer's disease with early onset	0.575	0.425
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.575	0.425
O63.2 Delayed delivery of second twin, triplet, etc.	0.575	0.425
S42.41 Fracture of lower end of humerus (open)	0.574	0.425
O43.8 Other placental disorders	0.574	0.426
S22.41 Multiple fractures of ribs (open)	0.574	0.426
O34.3 Maternal care for cervical incompetence	0.573	0.427
Y43.1 Antineoplastic antimetabolites	0.573	0.427
I27.1 Kyphoscoliotic heart disease	0.573	0.427
I61.8 Other intracerebral haemorrhage	0.572	0.427
I61.6 Intracerebral haemorrhage, multiple localised	0.572	0.427
I61.4 Intracerebral haemorrhage in cerebellum	0.572	0.427
I61.3 Intracerebral haemorrhage in brain stem	0.572	0.427
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.572	0.427
O34.4 Maternal care for other abnormalities of cervix	0.572	0.428
S29 Other and unspecified injuries of thorax	0.572	0.428
I27.8 Other specified pulmonary heart diseases	0.572	0.428
A19 Miliary tuberculosis	0.572	0.428
A18 Tuberculosis of other organs	0.572	0.428
A17 Tuberculosis of nervous system	0.572	0.428
T18.1 Foreign body in oesophagus	0.571	0.429
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.570	0.430
O92.1 Cracked nipple associated with childbirth	0.570	0.430
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.570	0.430
S05.9 Injury of eye and orbit, part unspecified	0.570	0.430
X10 Contact with hot drinks, food, fats and cooking oils	0.570	0.430
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.569	0.431
F64 Gender identity disorders	0.568	0.432
I20.9 Angina pectoris, unspecified	0.568	0.432
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident	0.568	0.432
D55-D59 Haemolytic anaemias	0.568	0.432
V17 Pedal cyclist injured in collision with fixed or stationary object	0.567	0.432
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.567	0.433
S21.2 Open wound of back wall of thorax	0.567	0.433
S82.8 Fractures of other parts of lower leg	0.566	0.434
O66.9 Obstructed labour, unspecified	0.565	0.434
O66.8 Other specified obstructed labour	0.565	0.434
O66.4 Failed trial of labour, unspecified	0.565	0.434

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations