TreeWAS – Variant ID: rs61730505

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
Chapter XIV Diseases of the genitourinary system	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
N20-N23 Urolithiasis	0.999	0.001	0.000
Chapter VI Diseases of the nervous system	0.999	0.001	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.998	0.002	0.000
N23 Unspecified renal colic	0.998	0.002	0.000
N10-N16 Renal tubulo-interstitial diseases	0.993	0.007	0.000
I60-I69 Cerebrovascular diseases	0.992	0.008	0.000
G90-G99 Other disorders of the nervous system	0.992	0.008	0.000
Chapter XI Diseases of the digestive system	0.987	0.013	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.986	0.014	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.985	0.015	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.980	0.020	0.000
N13 Obstructive and reflux uropathy	0.980	0.020	0.000
Chapter XX External causes of morbidity and mortality	0.973	0.027	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.969	0.031	0.000
G93 Other disorders of brain	0.968	0.032	0.000
N40-N51 Diseases of male genital organs	0.965	0.035	0.000
Chapter VIII Diseases of the ear and mastoid process	0.963	0.037	0.000
I77 Other disorders of arteries and arterioles	0.955	0.045	0.000
I63 Cerebral infarction	0.955	0.045	0.000
I25.2 Old myocardial infarction	0.949	0.051	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.945	0.055	0.000
K14 Diseases of tongue	0.942	0.058	0.000
I71 Aortic aneurysm and dissection	0.941	0.059	0.000
N13.3 Other and unspecified hydronephrosis	0.932	0.068	0.000
S80-S89 Injuries to the knee and lower leg	0.928	0.072	0.000
I74 Arterial embolism and thrombosis	0.927	0.073	0.000
Chapter V Mental and behavioural disorders	0.926	0.074	0.000
I24 Other acute ischaemic heart diseases	0.923	0.077	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.922	0.078	0.000
N48 Other disorders of penis	0.920	0.080	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.919	0.081	0.000
K14.8 Other diseases of tongue	0.916	0.084	0.000
M45-M49 Spondylopathies	0.915	0.085	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.912	0.088	0.000
K04 Diseases of pulp and periapical tissues	0.908	0.092	0.000
N20 Calculus of kidney and ureter	0.904	0.096	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.901	0.099	0.000
H60-H62 Diseases of external ear	0.900	0.100	0.000
K50-K52 Noninfective enteritis and colitis	0.895	0.105	0.000
S60-S69 Injuries to the wrist and hand	0.888	0.112	0.000
N48.6 Balanitis xerotica obliterans	0.885	0.115	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.881	0.119	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.879	0.121	0.000
I24.8 Other forms of acute ischaemic heart disease	0.875	0.125	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.873	0.127	0.000
T81 Complications of procedures, not elsewhere classified	0.872	0.128	0.000
I67 Other cerebrovascular diseases	0.871	0.129	0.000
G70-G73 Diseases of myoneural junction and muscle	0.868	0.132	0.000
K51 Ulcerative colitis	0.867	0.133	0.000
G93.3 Postviral fatigue syndrome	0.866	0.134	0.000
I73 Other peripheral vascular diseases	0.864	0.136	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.859	0.141	0.000
G95 Other diseases of spinal cord	0.857	0.143	0.000
M15-M19 Arthrosis	0.855	0.145	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.849	0.151	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.848	0.152	0.000
G93.4 Encephalopathy, unspecified	0.847	0.153	0.000
K70-K77 Diseases of liver	0.845	0.155	0.000
I63.9 Cerebral infarction, unspecified	0.841	0.159	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.840	0.160	0.000
E10-E14 Diabetes mellitus	0.838	0.162	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.836	0.164	0.000
G93.0 Cerebral cysts	0.835	0.165	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.835	0.165	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.834	0.166	0.000
N13.8 Other obstructive and reflux uropathy	0.833	0.167	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.833	0.167	0.000
I74.5 Embolism and thrombosis of iliac artery	0.832	0.168	0.000
M46 Other inflammatory spondylopathies	0.829	0.171	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.827	0.173	0.000
K35-K38 Diseases of appendix	0.827	0.173	0.000
G90 Disorders of autonomic nervous system	0.827	0.173	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.825	0.175	0.000
H61 Other disorders of external ear	0.825	0.175	0.000
I61 Intracerebral haemorrhage	0.823	0.177	0.000
S10-S19 Injuries to the neck	0.822	0.178	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.821	0.179	0.000
I22 Subsequent myocardial infarction	0.820	0.180	0.000
E10 Insulin-dependent diabetes mellitus	0.815	0.185	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.814	0.186	0.000
S90-S99 Injuries to the ankle and foot	0.813	0.187	0.000
H65-H75 Diseases of middle ear and mastoid	0.811	0.189	0.000
K51.9 Ulcerative colitis, unspecified	0.810	0.190	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.810	0.190	0.000
T93 Sequelae of injuries of lower limb	0.808	0.192	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.808	0.192	0.000
K02 Dental caries	0.805	0.195	0.000
S00-S09 Injuries to the head	0.803	0.197	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.802	0.198	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.801	0.199	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.799	0.201	0.000
K10 Other diseases of jaws	0.798	0.202	0.000
I67.9 Cerebrovascular disease, unspecified	0.796	0.204	0.000
M18 Arthrosis of first carpometacarpal joint	0.794	0.206	0.000
K04.6 Periapical abscess with sinus	0.794	0.206	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.793	0.207	0.000
S80 Superficial injury of lower leg	0.793	0.207	0.000
N20.1 Calculus of ureter	0.792	0.208	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.792	0.208	0.000
M05-M14 Inflammatory polyarthropathies	0.790	0.210	0.000
S40-S49 Injuries to the shoulder and upper arm	0.790	0.210	0.000
S62 Fracture at wrist and hand level	0.790	0.210	0.000
G30-G32 Other degenerative diseases of the nervous system	0.789	0.211	0.000
K65-K67 Diseases of peritoneum	0.789	0.211	0.000
W00-W19 Falls	0.788	0.212	0.000
E11 Non-insulin-dependent diabetes mellitus	0.785	0.215	0.000
I77.1 Stricture of artery	0.783	0.217	0.000
I73.9 Peripheral vascular disease, unspecified	0.782	0.218	0.000
Chapter XXII Codes for special purposes	0.782	0.218	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.780	0.220	0.000
N43 Hydrocele and spermatocele	0.779	0.221	0.000
G35 Multiple sclerosis	0.778	0.222	0.000
I69 Sequelae of cerebrovascular disease	0.777	0.223	0.000
G40-G47 Episodic and paroxysmal disorders	0.776	0.224	0.000
K04.5 Chronic apical periodontitis	0.775	0.225	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.775	0.225	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.774	0.226	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.774	0.226	0.000
E10.9 Without complications	0.771	0.229	0.000
M65-M68 Disorders of synovium and tendon	0.770	0.230	0.000
G20-G26 Extrapyramidal and movement disorders	0.770	0.230	0.000
N20.0 Calculus of kidney	0.767	0.233	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.767	0.233	0.000
N99-N99 Other disorders of the genitourinary system	0.767	0.233	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.766	0.234	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.766	0.234	0.000
K12 Stomatitis and related lesions	0.764	0.236	0.000
I72 Other aneurysm	0.763	0.237	0.000
T66-T78 Other and unspecified effects of external causes	0.762	0.238	0.000
G93.8 Other specified disorders of brain	0.761	0.239	0.000
K14.9 Disease of tongue, unspecified	0.761	0.239	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.761	0.239	0.000
S82 Fracture of lower leg, including ankle	0.760	0.240	0.000
S68 Traumatic amputation of wrist and hand	0.760	0.240	0.000
N45 Orchitis and epididymitis	0.759	0.240	0.000
T88.5 Other complications of anaesthesia	0.759	0.241	0.000
M00-M03 Infectious arthropathies	0.759	0.241	0.000
Y84.8 Other medical procedures	0.759	0.241	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.759	0.241	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.758	0.242	0.000
G96 Other disorders of central nervous system	0.758	0.242	0.000
M20-M25 Other joint disorders	0.757	0.242	0.001
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.758	0.242	0.000
K72 Hepatic failure, not elsewhere classified	0.758	0.242	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.757	0.243	0.000
S70-S79 Injuries to the hip and thigh	0.755	0.245	0.000
G70 Myasthenia gravis and other myoneural disorders	0.754	0.246	0.000
K90-K93 Other diseases of the digestive system	0.753	0.247	0.000
H72 Perforation of tympanic membrane	0.750	0.250	0.000
V80-V89 Other land transport accidents	0.749	0.251	0.000
K09 Cysts of oral region, not elsewhere classified	0.748	0.252	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.747	0.252	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.747	0.253	0.000
H60 Otitis externa	0.746	0.254	0.000
F10.0 Acute intoxication	0.746	0.254	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.746	0.254	0.000
N50 Other disorders of male genital organs	0.745	0.255	0.000
D68 Other coagulation defects	0.745	0.255	0.000
H90-H95 Other disorders of ear	0.744	0.255	0.000
N13.6 Pyonephrosis	0.744	0.256	0.000
X60-X84 Intentional self-harm	0.743	0.257	0.000
N21 Calculus of lower urinary tract	0.740	0.260	0.000
I25.3 Aneurysm of heart	0.739	0.260	0.000
T91 Sequelae of injuries of neck and trunk	0.739	0.261	0.000
N42 Other disorders of prostate	0.738	0.262	0.000
M45 Ankylosing spondylitis	0.737	0.263	0.000
K08 Other disorders of teeth and supporting structures	0.736	0.264	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.736	0.264	0.000
K04.8 Radicular cyst	0.735	0.265	0.000
T90 Sequelae of injuries of head	0.734	0.266	0.000
Y95 Nosocomial condition	0.734	0.266	0.000
K51.4 Pseudopolyposis of colon	0.733	0.267	0.000
M86-M90 Other osteopathies	0.730	0.270	0.000
N40 Hyperplasia of prostate	0.730	0.270	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.729	0.271	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.727	0.273	0.000
V40-V49 Car occupant injured in transport accident	0.726	0.273	0.000
I77.8 Other specified disorders of arteries and arterioles	0.726	0.274	0.000
M25 Other joint disorders, not elsewhere classified	0.726	0.274	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.725	0.275	0.000
M60-M63 Disorders of muscles	0.722	0.278	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.722	0.278	0.000
N11 Chronic tubulo-interstitial nephritis	0.722	0.278	0.000
I63.8 Other cerebral infarction	0.722	0.278	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.722	0.278	0.000
S64 Injury of nerves at wrist and hand level	0.722	0.278	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.721	0.279	0.000
H61.0 Perichondritis of external ear	0.720	0.280	0.000
N48.0 Leukoplakia of penis	0.720	0.280	0.000
S81 Open wound of lower leg	0.719	0.281	0.000
S89 Other and unspecified injuries of lower leg	0.719	0.281	0.000
F60-F69 Disorders of adult personality and behaviour	0.719	0.281	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.719	0.281	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.719	0.281	0.000
M48 Other spondylopathies	0.718	0.282	0.000
K35 Acute appendicitis	0.718	0.282	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
I23 Certain current complications following acute myocardial infarction	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I25.4 Coronary artery aneurysm	0.717	0.283	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.716	0.284	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.715	0.285	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.713	0.287	0.000
G93.6 Cerebral oedema	0.712	0.287	0.000
V10-V19 Pedal cyclist injured in transport accident	0.712	0.287	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.712	0.288	0.000
N15 Other renal tubulo-interstitial diseases	0.712	0.288	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.712	0.288	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.712	0.288	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.711	0.289	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.711	0.289	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.711	0.289	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.711	0.289	0.000
G92 Toxic encephalopathy	0.711	0.289	0.000
K00 Disorders of tooth development and eruption	0.711	0.289	0.000
N48.4 Impotence of organic origin	0.711	0.289	0.000
N25-N29 Other disorders of kidney and ureter	0.710	0.290	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.710	0.290	0.000
K51.8 Other ulcerative colitis	0.709	0.291	0.000
F20 Schizophrenia	0.709	0.291	0.000
T98 Sequelae of other and unspecified effects of external causes	0.707	0.293	0.000
G95.8 Other specified diseases of spinal cord	0.707	0.293	0.000
G95.9 Disease of spinal cord, unspecified	0.706	0.294	0.000
H80-H83 Diseases of inner ear	0.703	0.297	0.000
K03 Other diseases of hard tissues of teeth	0.702	0.297	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.702	0.298	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.702	0.298	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.701	0.299	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.701	0.299	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.701	0.299	0.000
I67.8 Other specified cerebrovascular diseases	0.701	0.299	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.700	0.300	0.000
E11.9 Without complications	0.700	0.300	0.000
S62.3 Fracture of other metacarpal bone	0.700	0.300	0.000
K07 Dentofacial anomalies [including malocclusion]	0.698	0.302	0.000
Y35-Y36 Legal intervention and operations of war	0.697	0.303	0.000
Y10-Y34 Event of undetermined intent	0.697	0.303	0.000
Y00-Y09 Assault	0.697	0.303	0.000
X85-X99 Assault	0.697	0.303	0.000
X50-X57 Overexertion, travel and privation	0.697	0.303	0.000
X30-X39 Exposure to forces of nature	0.697	0.303	0.000
X20-X29 Contact with venomous animals and plants	0.697	0.303	0.000
X10-X19 Contact with heat and hot substances	0.697	0.303	0.000
X00-X09 Exposure to smoke, fire and flames	0.697	0.303	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.697	0.303	0.000
W75-W84 Other accidental threats to breathing	0.697	0.303	0.000
W65-W74 Accidental drowning and submersion	0.697	0.303	0.000
W50-W64 Exposure to animate mechanical forces	0.697	0.303	0.000
V98-V99 Other and unspecified transport accidents	0.697	0.303	0.000
V95-V97 Air and space transport accidents	0.697	0.303	0.000
V90-V94 Water transport accidents	0.697	0.303	0.000
V70-V79 Bus occupant injured in transport accident	0.697	0.303	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.697	0.303	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.697	0.303	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.697	0.303	0.000
V01-V09 Pedestrian injured in transport accident	0.697	0.303	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.697	0.303	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.696	0.304	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.695	0.305	0.000
G93.7 Reye's syndrome	0.694	0.306	0.000
G93.5 Compression of brain	0.694	0.306	0.000
G93.2 Benign intracranial hypertension	0.694	0.306	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.694	0.306	0.000
S91 Open wound of ankle and foot	0.694	0.306	0.000
D60-D64 Aplastic and other anaemias	0.694	0.306	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.694	0.306	0.000
Y40 Systemic antibiotics	0.693	0.307	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.692	0.308	0.000
N46 Male infertility	0.692	0.308	0.000
N44 Torsion of testis	0.692	0.308	0.000
E10.3 With ophthalmic complications	0.692	0.308	0.000
S09 Other and unspecified injuries of head	0.692	0.308	0.000
F80-F89 Disorders of psychological development	0.691	0.309	0.000
M91-M94 Chondropathies	0.691	0.309	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.691	0.309	0.000
M47 Spondylosis	0.691	0.309	0.000
S80.9 Superficial injury of lower leg, unspecified	0.689	0.311	0.000
T79-T79 Certain early complications of trauma	0.688	0.312	0.000
N13.4 Hydroureter	0.687	0.313	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.687	0.313	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.685	0.315	0.000
I77.5 Necrosis of artery	0.685	0.315	0.000
I77.4 Coeliac artery compression syndrome	0.685	0.315	0.000
I77.3 Arterial fibromuscular dysplasia	0.685	0.315	0.000
I77.2 Rupture of artery	0.685	0.315	0.000
I77.0 Arteriovenous fistula, acquired	0.685	0.315	0.000
S60 Superficial injury of wrist and hand	0.685	0.315	0.000
T81.9 Unspecified complication of procedure	0.685	0.315	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.685	0.315	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.685	0.315	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.685	0.315	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.685	0.315	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.684	0.316	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.683	0.317	0.000
I70 Atherosclerosis	0.682	0.318	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.682	0.318	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.682	0.318	0.000
S82.0 Fracture of patella	0.679	0.321	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.679	0.321	0.000
K02.9 Dental caries, unspecified	0.679	0.321	0.000
G37 Other demyelinating diseases of central nervous system	0.678	0.322	0.000
T87 Complications peculiar to reattachment and amputation	0.678	0.322	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.678	0.322	0.000
M25.4 Effusion of joint	0.677	0.323	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.677	0.323	0.000
I25.5 Ischaemic cardiomyopathy	0.677	0.323	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.676	0.324	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.676	0.324	0.000
V20-V29 Motorcycle rider injured in transport accident	0.676	0.324	0.000
G93.9 Disorder of brain, unspecified	0.676	0.324	0.000
N48.2 Other inflammatory disorders of penis	0.676	0.324	0.000
K14.6 Glossodynia	0.675	0.324	0.000
K14.5 Plicated tongue	0.675	0.324	0.000
K14.4 Atrophy of tongue papillae	0.675	0.324	0.000
K14.3 Hypertrophy of tongue papillae	0.675	0.324	0.000
K14.2 Median rhomboid glossitis	0.675	0.324	0.000
K14.1 Geographic tongue	0.675	0.324	0.000
S50-S59 Injuries to the elbow and forearm	0.675	0.325	0.000
S42 Fracture of shoulder and upper arm	0.675	0.325	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.675	0.325	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.675	0.325	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.675	0.325	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.675	0.325	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.675	0.325	0.000
Q60-Q64 Congenital malformations of the urinary system	0.675	0.325	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.672	0.328	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.672	0.328	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.672	0.328	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.672	0.328	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.671	0.328	0.000
M19 Other arthrosis	0.671	0.329	0.000
N48.1 Balanoposthitis	0.669	0.331	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.668	0.332	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.668	0.332	0.000
G72 Other myopathies	0.667	0.333	0.000
S20-S29 Injuries to the thorax	0.666	0.333	0.000
F10.2 Dependence syndrome	0.666	0.334	0.000
S88 Traumatic amputation of lower leg	0.665	0.334	0.000
S87 Crushing injury of lower leg	0.665	0.334	0.000
S86 Injury of muscle and tendon at lower leg level	0.665	0.334	0.000
S85 Injury of blood vessels at lower leg level	0.665	0.334	0.000
S84 Injury of nerves at lower leg level	0.665	0.334	0.000
I60 Subarachnoid haemorrhage	0.665	0.334	0.000
I65.2 Occlusion and stenosis of carotid artery	0.665	0.335	0.000
I74.8 Embolism and thrombosis of other arteries	0.664	0.335	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.664	0.335	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.664	0.335	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.664	0.335	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.665	0.335	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.664	0.336	0.000
F70-F79 Mental retardation	0.664	0.336	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.664	0.336	0.000
K83 Other diseases of biliary tract	0.663	0.337	0.000
K76 Other diseases of liver	0.663	0.337	0.000
S06 Intracranial injury	0.663	0.337	0.000
T86 Failure and rejection of transplanted organs and tissues	0.663	0.337	0.000
I24.1 Dressler's syndrome	0.662	0.338	0.000
T95 Sequelae of burns, corrosions and frostbite	0.661	0.339	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.661	0.339	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.661	0.339	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.661	0.339	0.000
K05 Gingivitis and periodontal diseases	0.661	0.339	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.661	0.339	0.000
G40 Epilepsy	0.660	0.340	0.000
N48.9 Disorder of penis, unspecified	0.660	0.340	0.000
N48.5 Ulcer of penis	0.660	0.340	0.000
N48.3 Priapism	0.660	0.340	0.000
E10.1 With ketoacidosis	0.659	0.341	0.000
I22.8 Subsequent myocardial infarction of other sites	0.657	0.343	0.000
E40-E46 Malnutrition	0.657	0.343	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.657	0.343	0.000
M49 Spondylopathies in diseases classified elsewhere	0.656	0.344	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.655	0.345	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.655	0.345	0.000
M17 Gonarthrosis [arthrosis of knee]	0.655	0.345	0.000
D68.2 Hereditary deficiency of other clotting factors	0.655	0.345	0.000
I61.8 Other intracerebral haemorrhage	0.654	0.346	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.654	0.346	0.000
S30.1 Contusion of abdominal wall	0.654	0.346	0.000
K10.8 Other specified diseases of jaws	0.654	0.346	0.000
D80-D89 Certain disorders involving the immune mechanism	0.653	0.347	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.653	0.347	0.000
K51.2 Ulcerative (chronic) proctitis	0.653	0.347	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.652	0.348	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.651	0.349	0.000
K04.3 Abnormal hard tissue formation in pulp	0.651	0.349	0.000
K04.2 Pulp degeneration	0.651	0.349	0.000
K04.1 Necrosis of pulp	0.651	0.349	0.000
K04.0 Pulpitis	0.651	0.349	0.000
H61.9 Disorder of external ear, unspecified	0.650	0.350	0.000
M25.7 Osteophyte	0.649	0.351	0.000
N20.9 Urinary calculus, unspecified	0.648	0.352	0.000
K72.0 Acute and subacute hepatic failure	0.648	0.352	0.000
K13 Other diseases of lip and oral mucosa	0.646	0.354	0.000
D55-D59 Haemolytic anaemias	0.646	0.354	0.000
N43.3 Hydrocele, unspecified	0.646	0.354	0.000
G70.9 Myoneural disorder, unspecified	0.646	0.354	0.000
E11.3 With ophthalmic complications	0.646	0.354	0.000
S69 Other and unspecified injuries of wrist and hand	0.645	0.354	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.645	0.355	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.645	0.355	0.000
M05 Seropositive rheumatoid arthritis	0.645	0.355	0.000
S32 Fracture of lumbar spine and pelvis	0.644	0.356	0.000
T93.2 Sequelae of other fractures of lower limb	0.643	0.357	0.000
T93.0 Sequelae of open wound of lower limb	0.643	0.357	0.000
K11 Diseases of salivary glands	0.642	0.358	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.642	0.358	0.000
I71.0 Dissection of aorta [any part]	0.641	0.359	0.000
K92 Other diseases of digestive system	0.640	0.360	0.000
M25.46 Effusion of joint (Lower leg)	0.640	0.360	0.000
D66 Hereditary factor VIII deficiency	0.640	0.360	0.000
F17.1 Harmful use	0.639	0.361	0.000
M13 Other arthritis	0.638	0.362	0.000
K66 Other disorders of peritoneum	0.638	0.362	0.000
S65 Injury of blood vessels at wrist and hand level	0.636	0.363	0.000
H61.8 Other specified disorders of external ear	0.636	0.364	0.000
W06 Fall involving bed	0.636	0.364	0.000
K72.9 Hepatic failure, unspecified	0.636	0.364	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.635	0.365	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.635	0.365	0.000
K75 Other inflammatory liver diseases	0.634	0.366	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.634	0.366	0.000
D68.5 Primary Thrombophilia	0.634	0.366	0.000
H60.9 Otitis externa, unspecified	0.633	0.367	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.633	0.367	0.000
M07 Psoriatic and enteropathic arthropathies	0.633	0.367	0.000
G36 Other acute disseminated demyelination	0.632	0.368	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.632	0.368	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.632	0.368	0.000
H74 Other disorders of middle ear and mastoid	0.631	0.369	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.630	0.370	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.630	0.370	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.630	0.370	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.630	0.370	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.630	0.370	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.630	0.370	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.630	0.370	0.000
F11 Mental and behavioural disorders due to use of opioids	0.630	0.370	0.000
G61 Inflammatory polyneuropathy	0.630	0.370	0.000
G43 Migraine	0.630	0.370	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.628	0.372	0.000
H92 Otalgia and effusion of ear	0.627	0.373	0.000
N50.9 Disorder of male genital organs, unspecified	0.627	0.373	0.000
F10.4 Withdrawal state with delirium	0.627	0.373	0.000
I69.3 Sequelae of cerebral infarction	0.627	0.373	0.000
H61.2 Impacted cerumen	0.627	0.373	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.626	0.374	0.000
M80-M85 Disorders of bone density and structure	0.626	0.374	0.000
T88.9 Complication of surgical and medical care, unspecified	0.626	0.374	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.626	0.374	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.626	0.374	0.000
T88.2 Shock due to anaesthesia	0.626	0.374	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.626	0.374	0.000
T88.0 Infection following immunisation	0.626	0.374	0.000
K73 Chronic hepatitis, not elsewhere classified	0.625	0.374	0.000
S67 Crushing injury of wrist and hand	0.625	0.375	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.625	0.375	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.625	0.375	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.625	0.375	0.000
I62 Other nontraumatic intracranial haemorrhage	0.624	0.375	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.624	0.376	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.624	0.376	0.000
I67.5 Moyamoya disease	0.624	0.376	0.000
I67.4 Hypertensive encephalopathy	0.624	0.376	0.000
I67.3 Progressive vascular leukoencephalopathy	0.624	0.376	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.624	0.376	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.622	0.377	0.000
G71 Primary disorders of muscles	0.622	0.377	0.000
K51.5 Mucosal proctocolitis	0.622	0.378	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.622	0.378	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.622	0.378	0.000
M65 Synovitis and tenosynovitis	0.621	0.379	0.000
S82.00 Fracture of patella (closed)	0.621	0.379	0.000
M30 Polyarteritis nodosa and related conditions	0.620	0.380	0.001
G20 Parkinson's disease	0.620	0.380	0.000
T92 Sequelae of injuries of upper limb	0.620	0.380	0.000
I73.8 Other specified peripheral vascular diseases	0.619	0.380	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.619	0.380	0.000
E11.8 With unspecified complications	0.619	0.381	0.000
Y52 Agents primarily affecting the cardiovascular system	0.618	0.382	0.000
M47.8 Other spondylosis	0.618	0.382	0.000
K82 Other diseases of gallbladder	0.617	0.383	0.000
F20.9 Schizophrenia, unspecified	0.617	0.383	0.000
W18 Other fall on same level	0.616	0.384	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.616	0.384	0.000
K37 Unspecified appendicitis	0.616	0.384	0.000
N20.2 Calculus of kidney with calculus of ureter	0.616	0.384	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.615	0.385	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations