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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61791114
log Bayes Factor = 15.9998
Chromosome 3   position 170,748,859  (GRCh37) Explore rs61791114 on Ensembl!
Variant rs61791114 is part of Cluster X0124

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
0.999 0.001 0.000
M06 Other rheumatoid arthritis
0.999 0.001 0.000
M06.9 Rheumatoid arthritis, unspecified
0.999 0.001 0.000
I50 Heart failure
0.997 0.003 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.994 0.006 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.993 0.007 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.993 0.007 0.000
Chapter XI Diseases of the digestive system
0.986 0.014 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.984 0.016 0.000
I50.9 Heart failure, unspecified
0.983 0.017 0.000
Chapter XXI Factors influencing health status and contact with health services
0.982 0.018 0.000
Chapter X Diseases of the respiratory system
0.977 0.023 0.000
M70-M79 Other soft tissue disorders
0.975 0.025 0.000
Chapter XX External causes of morbidity and mortality
0.973 0.027 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.972 0.028 0.000
Chapter VI Diseases of the nervous system
0.961 0.039 0.000
I50.0 Congestive heart failure
0.960 0.040 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.958 0.042 0.000
J40-J47 Chronic lower respiratory diseases
0.957 0.043 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.956 0.044 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.956 0.044 0.000
J44 Other chronic obstructive pulmonary disease
0.953 0.047 0.000
K70-K77 Diseases of liver
0.938 0.062 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.938 0.062 0.000
L20-L30 Dermatitis and eczema
0.937 0.063 0.000
K35-K38 Diseases of appendix
0.937 0.063 0.000
R15 Faecal incontinence
0.936 0.064 0.000
Chapter V Mental and behavioural disorders
0.934 0.066 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.933 0.067 0.000
Chapter XIV Diseases of the genitourinary system
0.930 0.070 0.000
I35 Nonrheumatic aortic valve disorders
0.928 0.072 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.927 0.073 0.000
R10 Abdominal and pelvic pain
0.927 0.073 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.925 0.075 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.920 0.080 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.917 0.083 0.000
I31 Other diseases of pericardium
0.917 0.083 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.915 0.085 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.908 0.092 0.000
Chapter I Certain infectious and parasitic diseases
0.902 0.098 0.000
K22 Other diseases of oesophagus
0.899 0.101 0.000
R10.1 Pain localised to upper abdomen
0.895 0.105 0.000
I85 Oesophageal varices
0.894 0.106 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.892 0.108 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.892 0.108 0.000
I73 Other peripheral vascular diseases
0.886 0.114 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.885 0.115 0.000
K35 Acute appendicitis
0.884 0.116 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.883 0.117 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.878 0.122 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.876 0.124 0.000
K82 Other diseases of gallbladder
0.875 0.125 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.875 0.125 0.000
R47-R49 Symptoms and signs involving speech and voice
0.874 0.126 0.000
I31.3 Pericardial effusion (noninflammatory)
0.872 0.128 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.869 0.131 0.000
K22.1 Ulcer of oesophagus
0.866 0.134 0.000
M75 Shoulder lesions
0.865 0.135 0.000
F10.1 Harmful use
0.864 0.136 0.000
I46 Cardiac arrest
0.863 0.137 0.000
Z50 Care involving use of rehabilitation procedures
0.862 0.138 0.000
M79.0 Rheumatism, unspecified
0.859 0.141 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.858 0.142 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.852 0.148 0.000
Chapter VIII Diseases of the ear and mastoid process
0.849 0.151 0.000
M07 Psoriatic and enteropathic arthropathies
0.849 0.151 0.000
N25-N29 Other disorders of kidney and ureter
0.847 0.153 0.000
L30 Other dermatitis
0.846 0.154 0.000
I78 Diseases of capillaries
0.846 0.154 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.845 0.155 0.000
I77 Other disorders of arteries and arterioles
0.841 0.159 0.000
G90-G99 Other disorders of the nervous system
0.839 0.161 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.838 0.162 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.837 0.163 0.000
R42 Dizziness and giddiness
0.835 0.165 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.833 0.167 0.000
I95 Hypotension
0.833 0.167 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.828 0.172 0.000
Z50.1 Other physical therapy
0.828 0.172 0.000
I60-I69 Cerebrovascular diseases
0.827 0.173 0.000
R11 Nausea and vomiting
0.826 0.174 0.000
I73.0 Raynaud's syndrome
0.826 0.174 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.826 0.174 0.000
I85.9 Oesophageal varices without bleeding
0.823 0.177 0.000
J95-J99 Other diseases of the respiratory system
0.822 0.178 0.000
A00-A09 Intestinal infectious diseases
0.819 0.181 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.818 0.182 0.000
K82.8 Other specified diseases of gallbladder
0.817 0.183 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.817 0.183 0.000
Z92 Personal history of medical treatment
0.816 0.184 0.000
Y40 Systemic antibiotics
0.815 0.185 0.000
I42 Cardiomyopathy
0.815 0.185 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.812 0.188 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.812 0.188 0.000
K83 Other diseases of biliary tract
0.812 0.188 0.000
I80 Phlebitis and thrombophlebitis
0.811 0.189 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.811 0.189 0.000
K76 Other diseases of liver
0.809 0.191 0.000
J20-J22 Other acute lower respiratory infections
0.808 0.192 0.000
R17 Unspecified jaundice
0.808 0.192 0.000
Y52 Agents primarily affecting the cardiovascular system
0.807 0.193 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.805 0.195 0.000
I74 Arterial embolism and thrombosis
0.803 0.197 0.000
I35.1 Aortic (valve) insufficiency
0.803 0.197 0.000
M79.7 Fibromyalgia
0.802 0.198 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.801 0.199 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.801 0.199 0.000
F30-F39 Mood [affective] disorders
0.800 0.200 0.000
M06.0 Seronegative rheumatoid arthritis
0.800 0.200 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.799 0.201 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.799 0.201 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.798 0.202 0.000
I83 Varicose veins of lower extremities
0.796 0.204 0.000
Y44 Agents primarily affecting blood constituents
0.795 0.205 0.000
R10.4 Other and unspecified abdominal pain
0.795 0.205 0.000
R41.0 Disorientation, unspecified
0.794 0.206 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.794 0.206 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.793 0.207 0.000
L05 Pilonidal cyst
0.793 0.207 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.792 0.208 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.790 0.210 0.000
L27 Dermatitis due to substances taken internally
0.790 0.210 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.790 0.210 0.000
N17-N19 Renal failure
0.788 0.212 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.787 0.213 0.000
R50-R69 General symptoms and signs
0.786 0.214 0.000
N20-N23 Urolithiasis
0.786 0.214 0.000
R45 Symptoms and signs involving emotional state
0.782 0.218 0.000
K31 Other diseases of stomach and duodenum
0.782 0.218 0.000
L30.9 Dermatitis, unspecified
0.781 0.219 0.000
M05 Seropositive rheumatoid arthritis
0.781 0.219 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.775 0.225 0.000
K22.5 Diverticulum of oesophagus, acquired
0.773 0.227 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.773 0.227 0.000
Z00.0 General medical examination
0.770 0.230 0.000
K74 Fibrosis and cirrhosis of liver
0.768 0.232 0.000
H65-H75 Diseases of middle ear and mastoid
0.766 0.234 0.000
L40-L45 Papulosquamous disorders
0.766 0.234 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.765 0.235 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.764 0.235 0.000
I71 Aortic aneurysm and dissection
0.764 0.236 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.764 0.236 0.000
K70 Alcoholic liver disease
0.763 0.236 0.000
M86-M90 Other osteopathies
0.762 0.238 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.761 0.239 0.000
I95.9 Hypotension, unspecified
0.760 0.240 0.000
K37 Unspecified appendicitis
0.760 0.240 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.760 0.240 0.000
Z45 Adjustment and management of implanted device
0.758 0.242 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.757 0.242 0.000
M13 Other arthritis
0.755 0.245 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.755 0.245 0.000
J45 Asthma
0.755 0.245 0.000
I86 Varicose veins of other sites
0.755 0.245 0.000
I10-I15 Hypertensive diseases
0.754 0.246 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.754 0.246 0.000
I33 Acute and subacute endocarditis
0.753 0.247 0.000
Z95.1 Presence of aortocoronary bypass graft
0.753 0.247 0.000
V20-V29 Motorcycle rider injured in transport accident
0.752 0.248 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.752 0.248 0.000
M77 Other enthesopathies
0.751 0.249 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.750 0.250 0.000
N99-N99 Other disorders of the genitourinary system
0.750 0.250 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.749 0.251 0.000
W20-W49 Exposure to inanimate mechanical forces
0.748 0.252 0.000
I72 Other aneurysm
0.748 0.252 0.000
I78.1 Naevus, nonneoplastic
0.747 0.253 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.747 0.253 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.746 0.254 0.000
J09-J18 Influenza and pneumonia
0.746 0.254 0.000
I51 Complications and ill-defined descriptions of heart disease
0.746 0.254 0.000
N23 Unspecified renal colic
0.746 0.254 0.000
N28.1 Cyst of kidney, acquired
0.745 0.255 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.744 0.256 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.743 0.257 0.000
G93 Other disorders of brain
0.742 0.258 0.000
Z83 Family history of other specific disorders
0.741 0.259 0.000
M07.3 Other psoriatic arthropathies
0.741 0.259 0.000
Z72 Problems related to lifestyle
0.738 0.262 0.000
I46.0 Cardiac arrest with successful resuscitation
0.738 0.262 0.000
I49 Other cardiac arrhythmias
0.738 0.262 0.000
K76.8 Other specified diseases of liver
0.737 0.263 0.000
I82 Other venous embolism and thrombosis
0.737 0.263 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.737 0.263 0.000
M79.1 Myalgia
0.737 0.263 0.000
I05-I09 Chronic rheumatic heart diseases
0.736 0.263 0.000
Z01.4 Gynaecological examination (general)(routine)
0.736 0.264 0.000
I20-I25 Ischaemic heart diseases
0.736 0.264 0.000
N17 Acute renal failure
0.735 0.265 0.000
Chapter VII Diseases of the eye and adnexa
0.733 0.267 0.000
I35.8 Other aortic valve disorders
0.732 0.268 0.000
W00-W19 Falls
0.731 0.269 0.000
K72 Hepatic failure, not elsewhere classified
0.731 0.269 0.000
R51 Headache
0.731 0.269 0.000
I85.0 Oesophageal varices with bleeding
0.729 0.270 0.000
I81 Portal vein thrombosis
0.729 0.271 0.000
M71 Other bursopathies
0.728 0.271 0.000
J60-J70 Lung diseases due to external agents
0.728 0.272 0.000
R49 Voice disturbances
0.728 0.272 0.000
I63 Cerebral infarction
0.728 0.272 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.727 0.273 0.000
R47 Speech disturbances, not elsewhere classified
0.727 0.273 0.000
L29 Pruritus
0.726 0.274 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.725 0.275 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.725 0.275 0.000
B99-B99 Other infectious diseases
0.725 0.275 0.000
F10.3 Withdrawal state
0.724 0.276 0.000
R16.1 Splenomegaly, not elsewhere classified
0.723 0.277 0.000
L60-L75 Disorders of skin appendages
0.721 0.279 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.721 0.279 0.000
K75 Other inflammatory liver diseases
0.721 0.279 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.719 0.281 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.718 0.282 0.000
M75.3 Calcific tendinitis of shoulder
0.718 0.282 0.000
Z72.0 Tobacco use
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N10-N16 Renal tubulo-interstitial diseases
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
I99 Other and unspecified disorders of circulatory system
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.716 0.284 0.000
M06.4 Inflammatory polyarthropathy
0.716 0.284 0.000
M06.3 Rheumatoid nodule
0.716 0.284 0.000
M06.2 Rheumatoid bursitis
0.716 0.284 0.000
M06.1 Adult-onset Still's disease
0.716 0.284 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.716 0.284 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.716 0.284 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.716 0.284 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.716 0.284 0.000
Z50.2 Alcohol rehabilitation
0.716 0.284 0.000
Y40.0 Penicillins
0.715 0.285 0.000
L50-L54 Urticaria and erythema
0.714 0.286 0.000
I60 Subarachnoid haemorrhage
0.713 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.713 0.287 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.713 0.287 0.000
L10-L14 Bullous disorders
0.712 0.288 0.000
K14 Diseases of tongue
0.710 0.290 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.710 0.290 0.000
F32 Depressive episode
0.710 0.290 0.000
G70-G73 Diseases of myoneural junction and muscle
0.709 0.290 0.000
Z42 Follow-up care involving plastic surgery
0.709 0.291 0.000
K83.0 Cholangitis
0.709 0.291 0.000
M79.79 Fibromyalgia (Site unspecified)
0.708 0.292 0.000
M65-M68 Disorders of synovium and tendon
0.707 0.293 0.000
Z95.0 Presence of cardiac pacemaker
0.706 0.294 0.000
M79.5 Residual foreign body in soft tissue
0.705 0.295 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.705 0.295 0.000
B15-B19 Viral hepatitis
0.703 0.296 0.000
A04 Other bacterial intestinal infections
0.703 0.296 0.000
L05.9 Pilonidal cyst without abscess
0.703 0.297 0.000
K35.8 Acute appendicitis, other and unspecified
0.703 0.297 0.000
Z95.2 Presence of prosthetic heart valve
0.702 0.298 0.000
Y45.2 Propionic acid derivatives
0.701 0.298 0.000
K82.4 Cholesterolosis of gallbladder
0.701 0.299 0.000
K22.0 Achalasia of cardia
0.700 0.300 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.700 0.300 0.000
M76 Enthesopathies of lower limb, excluding foot
0.699 0.301 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.699 0.301 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.699 0.301 0.000
K22.4 Dyskinesia of oesophagus
0.698 0.302 0.000
M11 Other crystal arthropathies
0.697 0.302 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.697 0.302 0.000
Y35-Y36 Legal intervention and operations of war
0.697 0.302 0.000
Y10-Y34 Event of undetermined intent
0.697 0.302 0.000
Y00-Y09 Assault
0.697 0.302 0.000
X85-X99 Assault
0.697 0.302 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.697 0.302 0.000
X50-X57 Overexertion, travel and privation
0.697 0.302 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.697 0.302 0.000
X30-X39 Exposure to forces of nature
0.697 0.302 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.302 0.000
X10-X19 Contact with heat and hot substances
0.697 0.302 0.000
X00-X09 Exposure to smoke, fire and flames
0.697 0.302 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.697 0.302 0.000
W75-W84 Other accidental threats to breathing
0.697 0.302 0.000
W65-W74 Accidental drowning and submersion
0.697 0.302 0.000
W50-W64 Exposure to animate mechanical forces
0.697 0.302 0.000
V98-V99 Other and unspecified transport accidents
0.697 0.302 0.000
V95-V97 Air and space transport accidents
0.697 0.302 0.000
V90-V94 Water transport accidents
0.697 0.302 0.000
V80-V89 Other land transport accidents
0.697 0.302 0.000
V70-V79 Bus occupant injured in transport accident
0.697 0.302 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.697 0.302 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.697 0.302 0.000
V40-V49 Car occupant injured in transport accident
0.697 0.302 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.697 0.302 0.000
V01-V09 Pedestrian injured in transport accident
0.697 0.302 0.000
L57.0 Actinic keratosis
0.697 0.303 0.000
M50-M54 Other dorsopathies
0.697 0.303 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.697 0.303 0.000
N17.9 Acute renal failure, unspecified
0.697 0.303 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.697 0.303 0.000
M75.4 Impingement syndrome of shoulder
0.697 0.303 0.000
Chapter XXII Codes for special purposes
0.695 0.304 0.000
Y95 Nosocomial condition
0.695 0.305 0.000
I50.1 Left ventricular failure
0.695 0.305 0.000
J46 Status asthmaticus
0.695 0.305 0.000
J00-J06 Acute upper respiratory infections
0.695 0.305 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.694 0.305 0.000
R41.3 Other amnesia
0.695 0.305 0.000
J98 Other respiratory disorders
0.694 0.306 0.000
Z95.4 Presence of other heart-valve replacement
0.694 0.306 0.000
I35.0 Aortic (valve) stenosis
0.693 0.307 0.000
F80-F89 Disorders of psychological development
0.692 0.308 0.000
G95 Other diseases of spinal cord
0.691 0.309 0.000
I45 Other conduction disorders
0.690 0.310 0.000
Z43 Attention to artificial openings
0.690 0.310 0.000
Z01.8 Other specified special examinations
0.688 0.312 0.000
I88 Nonspecific lymphadenitis
0.687 0.313 0.000
B95-B98 Bacterial, viral and other infectious agents
0.687 0.313 0.000
M79.6 Pain in limb
0.687 0.313 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.686 0.313 0.000
J41 Simple and mucopurulent chronic bronchitis
0.686 0.314 0.000
R46 Symptoms and signs involving appearance and behaviour
0.686 0.314 0.000
R43 Disturbances of smell and taste
0.686 0.314 0.000
Y59 Other and unspecified vaccines and biological substances
0.685 0.315 0.000
Y58 Bacterial vaccines
0.685 0.315 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.685 0.315 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.685 0.315 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.685 0.315 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.685 0.315 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.685 0.315 0.000
Y48 Anaesthetics and therapeutic gases
0.685 0.315 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.685 0.315 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.685 0.315 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.685 0.315 0.000
Y43 Primarily systemic agents
0.685 0.315 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.685 0.315 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.684 0.316 0.000
Z97 Presence of other devices
0.683 0.317 0.000
K82.9 Disease of gallbladder, unspecified
0.682 0.318 0.000
I35.9 Aortic valve disorder, unspecified
0.682 0.318 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.682 0.318 0.000
Y44.2 Anticoagulants
0.680 0.320 0.000
Q50-Q56 Congenital malformations of genital organs
0.679 0.320 0.000
G20-G26 Extrapyramidal and movement disorders
0.679 0.321 0.000
M75.5 Bursitis of shoulder
0.679 0.321 0.000
J43 Emphysema
0.679 0.321 0.000
M10 Gout
0.678 0.322 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.678 0.322 0.000
I70 Atherosclerosis
0.678 0.322 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.677 0.322 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.677 0.323 0.000
I87 Other disorders of veins
0.677 0.323 0.000
N00-N08 Glomerular diseases
0.676 0.324 0.000
Y57 Other and unspecified drugs and medicaments
0.676 0.324 0.000
Z48 Other surgical follow-up care
0.674 0.326 0.000
K22.2 Oesophageal obstruction
0.674 0.326 0.000
N40-N51 Diseases of male genital organs
0.674 0.326 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.673 0.326 0.000
Q60-Q64 Congenital malformations of the urinary system
0.673 0.327 0.000
I46.9 Cardiac arrest, unspecified
0.673 0.327 0.000
K77 Liver disorders in diseases classified elsewhere
0.673 0.327 0.000
K73 Chronic hepatitis, not elsewhere classified
0.673 0.327 0.000
K71 Toxic liver disease
0.673 0.327 0.000
S80-S89 Injuries to the knee and lower leg
0.673 0.327 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.672 0.328 0.000
L28 Lichen simplex chronicus and prurigo
0.672 0.328 0.000
L25 Unspecified contact dermatitis
0.672 0.328 0.000
L24 Irritant contact dermatitis
0.672 0.328 0.000
L23 Allergic contact dermatitis
0.672 0.328 0.000
L21 Seborrhoeic dermatitis
0.672 0.328 0.000
L20 Atopic dermatitis
0.672 0.328 0.000
L26 Exfoliative dermatitis
0.672 0.328 0.000
L22 Diaper [napkin] dermatitis
0.672 0.328 0.000
A80-A89 Viral infections of the central nervous system
0.672 0.328 0.000
K38 Other diseases of appendix
0.672 0.328 0.000
K36 Other appendicitis
0.672 0.328 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.671 0.329 0.000
K86 Other diseases of pancreas
0.671 0.329 0.000
K35.9 Acute appendicitis, unspecified
0.671 0.329 0.000
I42.9 Cardiomyopathy, unspecified
0.671 0.329 0.000
X60-X84 Intentional self-harm
0.671 0.329 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.670 0.330 0.000
F99-F99 Unspecified mental disorder
0.670 0.330 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.670 0.330 0.000
F70-F79 Mental retardation
0.670 0.330 0.000
F60-F69 Disorders of adult personality and behaviour
0.670 0.330 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.670 0.330 0.000
J42 Unspecified chronic bronchitis
0.670 0.330 0.000
R45.1 Restlessness and agitation
0.669 0.331 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.669 0.331 0.000
R60 Oedema, not elsewhere classified
0.669 0.331 0.000
M79.9 Soft tissue disorder, unspecified
0.669 0.331 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.669 0.331 0.000
M79.3 Panniculitis, unspecified
0.669 0.331 0.000
M79.2 Neuralgia and neuritis, unspecified
0.669 0.331 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.668 0.332 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.668 0.332 0.000
K08 Other disorders of teeth and supporting structures
0.668 0.332 0.000
M75.1 Rotator cuff syndrome
0.667 0.333 0.000
K83.8 Other specified diseases of biliary tract
0.667 0.333 0.000
Z93 Artificial opening status
0.665 0.335 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.665 0.335 0.000
H73 Other disorders of tympanic membrane
0.665 0.335 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.664 0.335 0.000
J90-J94 Other diseases of pleura
0.664 0.336 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.664 0.336 0.000
I49.8 Other specified cardiac arrhythmias
0.663 0.337 0.000
R13 Dysphagia
0.662 0.338 0.000
I38 Endocarditis, valve unspecified
0.662 0.338 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.661 0.339 0.000
D80-D89 Certain disorders involving the immune mechanism
0.660 0.340 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.659 0.340 0.000
M40-M43 Deforming dorsopathies
0.659 0.341 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.659 0.341 0.000
S90-S99 Injuries to the ankle and foot
0.659 0.341 0.000
L04 Acute lymphadenitis
0.657 0.342 0.000
L01 Impetigo
0.657 0.342 0.000
L00 Staphylococcal scalded skin syndrome
0.657 0.342 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.657 0.343 0.000
I31.8 Other specified diseases of pericardium
0.657 0.343 0.000
I31.2 Haemopericardium, not elsewhere classified
0.657 0.343 0.000
I31.1 Chronic constrictive pericarditis
0.657 0.343 0.000
I31.0 Chronic adhesive pericarditis
0.657 0.343 0.000
Z10 Routine general health check-up of defined subpopulation
0.656 0.344 0.000
Z94 Transplanted organ and tissue status
0.655 0.345 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.654 0.346 0.000
J22 Unspecified acute lower respiratory infection
0.653 0.347 0.000
K22.9 Disease of oesophagus, unspecified
0.653 0.347 0.000
Z45.8 Adjustment and management of other implanted devices
0.653 0.347 0.000
B35-B49 Mycoses
0.653 0.347 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.653 0.347 0.000
H71 Cholesteatoma of middle ear
0.652 0.348 0.000
K28 Gastrojejunal ulcer
0.651 0.349 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.651 0.349 0.000
V10-V19 Pedal cyclist injured in transport accident
0.651 0.349 0.000
N60-N64 Disorders of breast
0.650 0.350 0.000
K31.8 Other specified diseases of stomach and duodenum
0.650 0.350 0.000
M75.2 Bicipital tendinitis
0.650 0.350 0.000
G40-G47 Episodic and paroxysmal disorders
0.650 0.350 0.000
Z98 Other postsurgical states
0.649 0.351 0.000
I25 Chronic ischaemic heart disease
0.648 0.352 0.000
K76.6 Portal hypertension
0.648 0.352 0.000
R56 Convulsions, not elsewhere classified
0.648 0.352 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.647 0.353 0.000
Z92.3 Personal history of irradiation
0.647 0.353 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.646 0.353 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.646 0.354 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.646 0.354 0.000
B65-B83 Helminthiases
0.646 0.354 0.000
B50-B64 Protozoal diseases
0.646 0.354 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.646 0.354 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.646 0.354 0.000
A75-A79 Rickettsioses
0.646 0.354 0.000
A70-A74 Other diseases caused by chlamydiae
0.646 0.354 0.000
A65-A69 Other spirochaetal diseases
0.646 0.354 0.000
A20-A28 Certain zoonotic bacterial diseases
0.646 0.354 0.000
A15-A19 Tuberculosis
0.646 0.354 0.000
J45.9 Asthma, unspecified
0.646 0.354 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.646 0.354 0.000
K74.6 Other and unspecified cirrhosis of liver
0.646 0.354 0.000
Z83.7 Family history of diseases of the digestive system
0.645 0.354 0.000
K22.3 Perforation of oesophagus
0.644 0.356 0.000
Z00.6 Examination for normal comparison and control in clinical research programme
0.644 0.356 0.000
I63.9 Cerebral infarction, unspecified
0.643 0.357 0.000
R10.3 Pain localised to other parts of lower abdomen
0.642 0.358 0.000
L40 Psoriasis
0.642 0.358 0.000
Z50.0 Cardiac rehabilitation
0.642 0.358 0.000
I47 Paroxysmal tachycardia
0.641 0.359 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.640 0.359 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.640 0.360 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.640 0.360 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.640 0.360 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.640 0.360 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.640 0.360 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.640 0.360 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.640 0.360 0.000
F11 Mental and behavioural disorders due to use of opioids
0.640 0.360 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.640 0.360 0.000
Z49 Care involving dialysis
0.638 0.361 0.000
Z22 Carrier of infectious disease
0.637 0.362 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.636 0.364 0.000
I95.1 Orthostatic hypotension
0.636 0.364 0.000
I73.8 Other specified peripheral vascular diseases
0.635 0.365 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.635 0.365 0.000
G30-G32 Other degenerative diseases of the nervous system
0.635 0.365 0.000
Z54 Convalescence
0.634 0.366 0.000
Z52 Donors of organs and tissues
0.634 0.366 0.000
Z44 Fitting and adjustment of external prosthetic device
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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