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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61829222
log Bayes Factor = 27.9255
Chromosome 10   position 4,040,185  (GRCh37) Explore rs61829222 on Ensembl!
Variant rs61829222 is part of Cluster X0040

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.998 0.002 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.995 0.005 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
I25 Chronic ischaemic heart disease
0.992 0.008 0.000
B95-B98 Bacterial, viral and other infectious agents
0.991 0.009 0.000
I25.1 Atherosclerotic heart disease
0.988 0.012 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.986 0.014 0.000
Chapter VII Diseases of the eye and adnexa
0.984 0.016 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.980 0.020 0.000
Chapter XX External causes of morbidity and mortality
0.977 0.023 0.000
Chapter XI Diseases of the digestive system
0.977 0.023 0.000
M20 Acquired deformities of fingers and toes
0.975 0.025 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.970 0.030 0.000
I10-I15 Hypertensive diseases
0.968 0.032 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.963 0.037 0.000
D60-D64 Aplastic and other anaemias
0.962 0.038 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.958 0.042 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.958 0.042 0.000
M20.1 Hallux valgus (acquired)
0.956 0.044 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.955 0.045 0.000
I10 Essential (primary) hypertension
0.951 0.049 0.000
Chapter VIII Diseases of the ear and mastoid process
0.951 0.049 0.000
I30-I52 Other forms of heart disease
0.949 0.051 0.000
K20 Oesophagitis
0.948 0.052 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.948 0.052 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.946 0.054 0.000
H30-H36 Disorders of choroid and retina
0.942 0.058 0.000
D64 Other anaemias
0.941 0.059 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.937 0.063 0.000
Z92 Personal history of medical treatment
0.935 0.065 0.000
Chapter X Diseases of the respiratory system
0.935 0.065 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.933 0.067 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.930 0.070 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.929 0.071 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.929 0.071 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.927 0.073 0.000
D64.9 Anaemia, unspecified
0.927 0.073 0.000
I60-I69 Cerebrovascular diseases
0.923 0.077 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.923 0.077 0.000
H25-H28 Disorders of lens
0.920 0.080 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.920 0.080 0.000
Z53.0 Procedure not carried out because of contraindication
0.918 0.082 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.918 0.082 0.000
M23 Internal derangement of knee
0.917 0.083 0.000
M15-M19 Arthrosis
0.917 0.083 0.000
S60-S69 Injuries to the wrist and hand
0.917 0.083 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.914 0.086 0.000
L82 Seborrhoeic keratosis
0.912 0.088 0.000
A30-A49 Other bacterial diseases
0.907 0.093 0.000
L85 Other epidermal thickening
0.906 0.094 0.000
S80-S89 Injuries to the knee and lower leg
0.905 0.095 0.000
T66-T78 Other and unspecified effects of external causes
0.900 0.100 0.000
H26 Other cataract
0.899 0.101 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.896 0.104 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.895 0.105 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.895 0.105 0.000
I21 Acute myocardial infarction
0.895 0.105 0.000
D50-D53 Nutritional anaemias
0.893 0.107 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.892 0.108 0.000
H65-H75 Diseases of middle ear and mastoid
0.891 0.109 0.000
H26.9 Cataract, unspecified
0.887 0.113 0.000
Chapter XIV Diseases of the genitourinary system
0.887 0.113 0.000
E10-E14 Diabetes mellitus
0.886 0.114 0.000
M50-M54 Other dorsopathies
0.886 0.114 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.882 0.118 0.000
I22 Subsequent myocardial infarction
0.881 0.119 0.000
N17-N19 Renal failure
0.881 0.119 0.000
Z86 Personal history of certain other diseases
0.880 0.120 0.000
I20 Angina pectoris
0.878 0.122 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.875 0.125 0.000
S00-S09 Injuries to the head
0.872 0.128 0.000
L03 Cellulitis
0.872 0.128 0.000
N18 Chronic renal failure
0.871 0.129 0.000
L40-L45 Papulosquamous disorders
0.871 0.129 0.000
Z43 Attention to artificial openings
0.870 0.130 0.000
M80-M85 Disorders of bone density and structure
0.870 0.130 0.000
M23.3 Other meniscus derangements
0.865 0.134 0.000
O60-O75 Complications of labour and delivery
0.865 0.135 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.864 0.136 0.000
K22 Other diseases of oesophagus
0.861 0.139 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.860 0.140 0.000
Z86.4 Personal history of psychoactive substance abuse
0.858 0.142 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.858 0.142 0.000
H33 Retinal detachments and breaks
0.858 0.142 0.000
M25 Other joint disorders, not elsewhere classified
0.857 0.143 0.000
S40-S49 Injuries to the shoulder and upper arm
0.857 0.143 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.856 0.144 0.000
K26 Duodenal ulcer
0.854 0.146 0.000
Y83.6 Removal of other organ (partial) (total)
0.853 0.147 0.000
M05-M14 Inflammatory polyarthropathies
0.851 0.149 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.849 0.151 0.000
N18.3 Chronic kidney disease, stage 3
0.847 0.153 0.000
I42 Cardiomyopathy
0.847 0.153 0.000
D50 Iron deficiency anaemia
0.846 0.154 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.845 0.155 0.000
M45-M49 Spondylopathies
0.844 0.156 0.000
E70-E90 Metabolic disorders
0.844 0.156 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.844 0.156 0.000
M20.4 Other hammer toe(s) (acquired)
0.843 0.157 0.000
K35-K38 Diseases of appendix
0.843 0.157 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.838 0.162 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.837 0.163 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.837 0.163 0.000
Chapter II Neoplasms
0.835 0.165 0.000
M54 Dorsalgia
0.834 0.166 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.833 0.167 0.000
K31 Other diseases of stomach and duodenum
0.829 0.171 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.829 0.171 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.829 0.171 0.000
T78 Adverse effects, not elsewhere classified
0.828 0.172 0.000
J90-J94 Other diseases of pleura
0.828 0.172 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.827 0.173 0.000
M35 Other systemic involvement of connective tissue
0.827 0.173 0.000
J09-J18 Influenza and pneumonia
0.827 0.173 0.000
L89 Decubitus ulcer
0.825 0.175 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.825 0.175 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.824 0.176 0.000
I61 Intracerebral haemorrhage
0.824 0.176 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.821 0.179 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.820 0.180 0.000
Z60 Problems related to social environment
0.819 0.181 0.000
Z91.5 Personal history of self-harm
0.819 0.181 0.000
Z40 Prophylactic surgery
0.819 0.181 0.000
E10 Insulin-dependent diabetes mellitus
0.818 0.182 0.000
S20-S29 Injuries to the thorax
0.817 0.183 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.816 0.184 0.000
D50.8 Other iron deficiency anaemias
0.814 0.186 0.000
L85.8 Other specified epidermal thickening
0.813 0.187 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.813 0.187 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.811 0.189 0.000
M86-M90 Other osteopathies
0.810 0.189 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.810 0.190 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.810 0.190 0.000
I34 Nonrheumatic mitral valve disorders
0.809 0.191 0.000
K70-K77 Diseases of liver
0.808 0.192 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.808 0.192 0.000
K22.1 Ulcer of oesophagus
0.806 0.194 0.000
L40 Psoriasis
0.805 0.195 0.000
M16 Coxarthrosis [arthrosis of hip]
0.805 0.195 0.000
H90-H95 Other disorders of ear
0.804 0.196 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.804 0.196 0.000
H43-H45 Disorders of vitreous body and globe
0.803 0.197 0.000
Y83.4 Other reconstructive surgery
0.802 0.198 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.802 0.198 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.802 0.198 0.000
M34 Systemic sclerosis
0.801 0.198 0.000
I45 Other conduction disorders
0.801 0.199 0.000
H35 Other retinal disorders
0.800 0.200 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.799 0.201 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.798 0.202 0.000
B25-B34 Other viral diseases
0.797 0.203 0.000
K22.7 Barrett's oesophagus
0.797 0.203 0.000
Z47 Other orthopaedic follow-up care
0.797 0.203 0.000
L84 Corns and callosities
0.796 0.204 0.000
Z93 Artificial opening status
0.793 0.207 0.000
T42.4 Benzodiazepines
0.792 0.208 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.792 0.208 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.792 0.208 0.000
I60 Subarachnoid haemorrhage
0.790 0.210 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.788 0.212 0.000
L81 Other disorders of pigmentation
0.788 0.212 0.000
I35 Nonrheumatic aortic valve disorders
0.788 0.212 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.787 0.213 0.000
C15-C26 Malignant neoplasms of digestive organs
0.787 0.213 0.000
M54.5 Low back pain
0.784 0.216 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.782 0.218 0.000
Z91.6 Personal history of other physical trauma
0.781 0.219 0.000
Y83.9 Surgical procedure, unspecified
0.780 0.220 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.780 0.220 0.000
M20.5 Other deformities of toe(s) (acquired)
0.779 0.221 0.000
A49 Bacterial infection of unspecified site
0.778 0.222 0.000
A41 Other septicaemia
0.777 0.223 0.000
L03.1 Cellulitis of other parts of limb
0.776 0.224 0.000
Z50 Care involving use of rehabilitation procedures
0.776 0.224 0.000
I77 Other disorders of arteries and arterioles
0.775 0.225 0.000
I69 Sequelae of cerebrovascular disease
0.775 0.225 0.000
I25.3 Aneurysm of heart
0.774 0.226 0.000
I21.4 Acute subendocardial myocardial infarction
0.774 0.226 0.000
Z95.2 Presence of prosthetic heart valve
0.774 0.226 0.000
I42.0 Dilated cardiomyopathy
0.774 0.226 0.000
L05 Pilonidal cyst
0.773 0.227 0.000
L40.5 Arthropathic psoriasis
0.771 0.229 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.771 0.229 0.000
J60-J70 Lung diseases due to external agents
0.769 0.231 0.000
O80-O84 Delivery
0.769 0.231 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.768 0.231 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.767 0.233 0.000
A00-A09 Intestinal infectious diseases
0.765 0.235 0.000
Z60.2 Living alone
0.765 0.235 0.000
Z04 Examination and observation for other reasons
0.765 0.235 0.000
M25.5 Pain in joint
0.765 0.235 0.000
E00-E07 Disorders of thyroid gland
0.761 0.239 0.000
L90 Atrophic disorders of skin
0.761 0.239 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.761 0.239 0.000
J00-J06 Acute upper respiratory infections
0.760 0.240 0.000
I46 Cardiac arrest
0.759 0.241 0.000
H36 Retinal disorders in diseases classified elsewhere
0.758 0.241 0.000
I05-I09 Chronic rheumatic heart diseases
0.758 0.242 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.757 0.243 0.000
I73 Other peripheral vascular diseases
0.757 0.243 0.000
H71 Cholesteatoma of middle ear
0.756 0.244 0.000
T79-T79 Certain early complications of trauma
0.756 0.244 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.756 0.244 0.000
M21 Other acquired deformities of limbs
0.754 0.246 0.000
Z92.3 Personal history of irradiation
0.754 0.246 0.000
E11 Non-insulin-dependent diabetes mellitus
0.752 0.248 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.752 0.248 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.751 0.249 0.000
S42 Fracture of shoulder and upper arm
0.751 0.249 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.751 0.249 0.000
D61 Other aplastic anaemias
0.751 0.249 0.000
M47 Spondylosis
0.751 0.249 0.000
Z45 Adjustment and management of implanted device
0.750 0.250 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.748 0.252 0.000
S80 Superficial injury of lower leg
0.748 0.252 0.000
T43.2 Other and unspecified antidepressants
0.748 0.252 0.000
M54.56 Low back pain (Lumbar region)
0.748 0.252 0.000
H74 Other disorders of middle ear and mastoid
0.747 0.253 0.000
T81 Complications of procedures, not elsewhere classified
0.747 0.253 0.000
Z03.8 Observation for other suspected diseases and conditions
0.747 0.253 0.000
S61 Open wound of wrist and hand
0.747 0.253 0.000
T86 Failure and rejection of transplanted organs and tissues
0.747 0.253 0.000
K85 Acute pancreatitis
0.747 0.253 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.746 0.254 0.000
M24 Other specific joint derangements
0.746 0.254 0.000
H33.0 Retinal detachment with retinal break
0.745 0.255 0.000
I20.8 Other forms of angina pectoris
0.744 0.256 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.743 0.257 0.000
K81 Cholecystitis
0.743 0.257 0.000
Chapter XXII Codes for special purposes
0.743 0.257 0.000
N19 Unspecified renal failure
0.742 0.258 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.742 0.258 0.000
Z47.8 Other specified orthopaedic follow-up care
0.742 0.258 0.000
L03.2 Cellulitis of face
0.742 0.258 0.000
T78.4 Allergy, unspecified
0.742 0.258 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.742 0.258 0.000
J90 Pleural effusion, not elsewhere classified
0.740 0.260 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.740 0.260 0.000
W20-W49 Exposure to inanimate mechanical forces
0.738 0.262 0.000
M31 Other necrotising vasculopathies
0.738 0.262 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.738 0.262 0.000
S62 Fracture at wrist and hand level
0.737 0.263 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.737 0.263 0.000
I71 Aortic aneurysm and dissection
0.736 0.264 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.736 0.264 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.736 0.264 0.000
K09 Cysts of oral region, not elsewhere classified
0.736 0.264 0.000
H72 Perforation of tympanic membrane
0.735 0.265 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.735 0.265 0.000
K12 Stomatitis and related lesions
0.734 0.266 0.000
E50-E64 Other nutritional deficiencies
0.733 0.267 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.732 0.268 0.000
M84 Disorders of continuity of bone
0.732 0.268 0.000
I25.5 Ischaemic cardiomyopathy
0.730 0.270 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.730 0.270 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.730 0.270 0.000
I20.9 Angina pectoris, unspecified
0.729 0.271 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.729 0.271 0.000
Z42 Follow-up care involving plastic surgery
0.729 0.271 0.000
Z43.2 Attention to ileostomy
0.729 0.271 0.000
L85.9 Epidermal thickening, unspecified
0.728 0.272 0.000
Z94 Transplanted organ and tissue status
0.728 0.272 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.728 0.272 0.000
S82 Fracture of lower leg, including ankle
0.728 0.272 0.000
S70-S79 Injuries to the hip and thigh
0.728 0.272 0.000
Z36 Antenatal screening
0.727 0.273 0.000
E83 Disorders of mineral metabolism
0.727 0.273 0.000
I30 Acute pericarditis
0.727 0.273 0.000
D80-D89 Certain disorders involving the immune mechanism
0.726 0.274 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.725 0.275 0.000
M23.5 Chronic instability of knee
0.725 0.275 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.725 0.275 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.724 0.275 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.724 0.276 0.000
M18 Arthrosis of first carpometacarpal joint
0.723 0.277 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.723 0.277 0.000
M17 Gonarthrosis [arthrosis of knee]
0.723 0.277 0.000
H10-H13 Disorders of conjunctiva
0.721 0.279 0.000
Z52 Donors of organs and tissues
0.720 0.280 0.000
E10.9 Without complications
0.720 0.280 0.000
S64 Injury of nerves at wrist and hand level
0.720 0.280 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.719 0.281 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.719 0.281 0.000
M07 Psoriatic and enteropathic arthropathies
0.718 0.282 0.000
K04 Diseases of pulp and periapical tissues
0.718 0.282 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.718 0.282 0.000
N18.0 End-stage renal disease
0.718 0.282 0.000
Z89 Acquired absence of limb
0.718 0.282 0.000
M54.9 Dorsalgia, unspecified
0.717 0.283 0.000
H70 Mastoiditis and related conditions
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I22.8 Subsequent myocardial infarction of other sites
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
L10-L14 Bullous disorders
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
B99-B99 Other infectious diseases
0.715 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.715 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.284 0.000
B65-B83 Helminthiases
0.715 0.284 0.000
B50-B64 Protozoal diseases
0.715 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.284 0.000
B15-B19 Viral hepatitis
0.715 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.715 0.284 0.000
A75-A79 Rickettsioses
0.715 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.284 0.000
A65-A69 Other spirochaetal diseases
0.715 0.284 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.715 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.284 0.000
A15-A19 Tuberculosis
0.715 0.284 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.714 0.286 0.000
X60-X84 Intentional self-harm
0.714 0.286 0.000
S90-S99 Injuries to the ankle and foot
0.714 0.286 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.714 0.286 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.714 0.286 0.000
L94 Other localised connective tissue disorders
0.714 0.286 0.000
L93 Lupus erythematosus
0.714 0.286 0.000
L87 Transepidermal elimination disorders
0.714 0.286 0.000
L88 Pyoderma gangrenosum
0.714 0.286 0.000
L86 Keratoderma in diseases classified elsewhere
0.714 0.286 0.000
L83 Acanthosis nigricans
0.714 0.286 0.000
L80 Vitiligo
0.714 0.286 0.000
D55-D59 Haemolytic anaemias
0.713 0.287 0.000
K35 Acute appendicitis
0.712 0.288 0.000
L03.3 Cellulitis of trunk
0.712 0.288 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.712 0.288 0.000
S00 Superficial injury of head
0.711 0.289 0.000
I25.6 Silent myocardial ischaemia
0.711 0.289 0.000
I25.4 Coronary artery aneurysm
0.711 0.289 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.711 0.289 0.000
N00-N08 Glomerular diseases
0.711 0.289 0.000
B35-B49 Mycoses
0.710 0.290 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.710 0.290 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.708 0.292 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.708 0.292 0.000
Z41 Procedures for purposes other than remedying health state
0.708 0.292 0.000
H90 Conductive and sensorineural hearing loss
0.708 0.292 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.707 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.707 0.293 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.707 0.293 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.707 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.707 0.293 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.707 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
T36 Poisoning by systemic antibiotics
0.707 0.293 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.707 0.293 0.000
M81 Osteoporosis without pathological fracture
0.707 0.293 0.000
Z49 Care involving dialysis
0.707 0.293 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.706 0.294 0.000
T39.1 4-Aminophenol derivatives
0.706 0.294 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.706 0.294 0.000
H55-H59 Other disorders of eye and adnexa
0.706 0.294 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.706 0.294 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.705 0.295 0.000
Z92.0 Personal history of contraception
0.705 0.295 0.000
K76 Other diseases of liver
0.705 0.295 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.704 0.296 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.703 0.297 0.000
Z54 Convalescence
0.703 0.297 0.000
Z44 Fitting and adjustment of external prosthetic device
0.703 0.297 0.000
E89.0 Postprocedural hypothyroidism
0.701 0.299 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.701 0.299 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.700 0.300 0.000
Y35-Y36 Legal intervention and operations of war
0.700 0.300 0.000
Y10-Y34 Event of undetermined intent
0.700 0.300 0.000
Y00-Y09 Assault
0.700 0.300 0.000
X85-X99 Assault
0.700 0.300 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.700 0.300 0.000
X50-X57 Overexertion, travel and privation
0.700 0.300 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.700 0.300 0.000
X30-X39 Exposure to forces of nature
0.700 0.300 0.000
X20-X29 Contact with venomous animals and plants
0.700 0.300 0.000
X10-X19 Contact with heat and hot substances
0.700 0.300 0.000
X00-X09 Exposure to smoke, fire and flames
0.700 0.300 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.700 0.300 0.000
W75-W84 Other accidental threats to breathing
0.700 0.300 0.000
W65-W74 Accidental drowning and submersion
0.700 0.300 0.000
W50-W64 Exposure to animate mechanical forces
0.700 0.300 0.000
V98-V99 Other and unspecified transport accidents
0.700 0.300 0.000
V95-V97 Air and space transport accidents
0.700 0.300 0.000
V90-V94 Water transport accidents
0.700 0.300 0.000
V80-V89 Other land transport accidents
0.700 0.300 0.000
V70-V79 Bus occupant injured in transport accident
0.700 0.300 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.700 0.300 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.700 0.300 0.000
V40-V49 Car occupant injured in transport accident
0.700 0.300 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.700 0.300 0.000
V20-V29 Motorcycle rider injured in transport accident
0.700 0.300 0.000
V01-V09 Pedestrian injured in transport accident
0.700 0.300 0.000
M25.4 Effusion of joint
0.700 0.300 0.000
Z86.0 Personal history of other neoplasms
0.699 0.301 0.000
M20.3 Other deformity of hallux (acquired)
0.699 0.301 0.000
M20.0 Deformity of finger(s)
0.699 0.301 0.000
S06 Intracranial injury
0.699 0.301 0.000
T51 Toxic effect of alcohol
0.698 0.302 0.000
O70 Perineal laceration during delivery
0.698 0.302 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.698 0.302 0.000
J14 Pneumonia due to Haemophilus influenzae
0.697 0.303 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.697 0.303 0.000
M35.3 Polymyalgia rheumatica
0.697 0.303 0.000
I21.9 Acute myocardial infarction, unspecified
0.697 0.303 0.000
S81 Open wound of lower leg
0.696 0.304 0.000
I95 Hypotension
0.696 0.304 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.696 0.304 0.000
Z84 Family history of other conditions
0.695 0.305 0.000
Z81 Family history of mental and behavioural disorders
0.695 0.305 0.000
E20-E35 Disorders of other endocrine glands
0.695 0.305 0.000
I45.1 Other and unspecified right bundle-branch block
0.695 0.305 0.000
L08 Other local infections of skin and subcutaneous tissue
0.695 0.305 0.000
I15 Secondary hypertension
0.694 0.306 0.000
I13 Hypertensive heart and renal disease
0.694 0.306 0.000
I11 Hypertensive heart disease
0.694 0.306 0.000
L90.0 Lichen sclerosus et atrophicus
0.694 0.306 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.694 0.306 0.000
H80-H83 Diseases of inner ear
0.693 0.306 0.000
O36 Maternal care for other known or suspected foetal problems
0.693 0.307 0.000
M13 Other arthritis
0.692 0.308 0.000
C20 Malignant neoplasm of rectum
0.692 0.308 0.000
N18.4 Chronic kidney disease, stage 4
0.691 0.309 0.000
E40-E46 Malnutrition
0.691 0.309 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.690 0.310 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.689 0.310 0.000
M47.8 Other spondylosis
0.689 0.311 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.688 0.312 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.688 0.312 0.000
I67 Other cerebrovascular diseases
0.688 0.312 0.000
K22.0 Achalasia of cardia
0.687 0.313 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.687 0.313 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.687 0.313 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.687 0.313 0.000
K28 Gastrojejunal ulcer
0.687 0.313 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.687 0.313 0.000
O62 Abnormalities of forces of labour
0.686 0.313 0.000
E78.0 Pure hypercholesterolaemia
0.686 0.314 0.000
A49.0 Staphylococcal infection, unspecified
0.686 0.314 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.685 0.315 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.685 0.315 0.000
T85.2 Mechanical complication of intraocular lens
0.685 0.315 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.685 0.315 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.685 0.315 0.000
K50-K52 Noninfective enteritis and colitis
0.684 0.316 0.000
K27 Peptic ulcer, site unspecified
0.684 0.316 0.000
L91 Hypertrophic disorders of skin
0.684 0.316 0.000
C50-C50 Malignant neoplasm of breast
0.683 0.317 0.000
Chapter V Mental and behavioural disorders
0.683 0.317 0.000
M16.1 Other primary coxarthrosis
0.683 0.317 0.000
Z83 Family history of other specific disorders
0.682 0.317 0.000
Y44 Agents primarily affecting blood constituents
0.682 0.318 0.000
I38 Endocarditis, valve unspecified
0.681 0.319 0.000
I52 Other heart disorders in diseases classified elsewhere
0.681 0.319 0.000
I48 Atrial fibrillation and flutter
0.681 0.319 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.681 0.319 0.000
I41 Myocarditis in diseases classified elsewhere
0.681 0.319 0.000
I40 Acute myocarditis
0.681 0.319 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.681 0.319 0.000
I37 Pulmonary valve disorders
0.681 0.319 0.000
I36 Nonrheumatic tricuspid valve disorders
0.681 0.319 0.000
I33 Acute and subacute endocarditis
0.681 0.319 0.000
I32 Pericarditis in diseases classified elsewhere
0.681 0.319 0.000
H34 Retinal vascular occlusions
0.680 0.320 0.000
H44 Disorders of globe
0.680 0.320 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.680 0.320 0.000
M22 Disorders of patella
0.679 0.321 0.000
O85-O92 Complications predominantly related to the puerperium
0.679 0.321 0.000
N18.2 Chronic kidney disease, stage 2
0.678 0.322 0.000
S01 Open wound of head
0.678 0.322 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.677 0.323 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.677 0.323 0.000
J18 Pneumonia, organism unspecified
0.677 0.323 0.000
I77.1 Stricture of artery
0.677 0.323 0.000
N99-N99 Other disorders of the genitourinary system
0.677 0.323 0.000
K85.9 Acute pancreatitis, unspecified
0.676 0.324 0.000
D75 Other diseases of blood and blood-forming organs
0.676 0.324 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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