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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61854888
log Bayes Factor = 5.50877
Chromosome 10   position 90,928,961  (GRCh37) Explore rs61854888 on Ensembl!
Variant rs61854888 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
M20 Acquired deformities of fingers and toes
0.997 0.003 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.992 0.008 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.989 0.011 0.000
Chapter V Mental and behavioural disorders
0.982 0.018 0.000
M25 Other joint disorders, not elsewhere classified
0.978 0.022 0.000
M20.1 Hallux valgus (acquired)
0.969 0.031 0.000
J90-J94 Other diseases of pleura
0.967 0.033 0.000
M05-M14 Inflammatory polyarthropathies
0.941 0.059 0.000
M25.5 Pain in joint
0.938 0.062 0.000
J90 Pleural effusion, not elsewhere classified
0.934 0.066 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.933 0.067 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.932 0.068 0.000
Chapter II Neoplasms
0.925 0.075 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.922 0.078 0.000
R13 Dysphagia
0.915 0.085 0.000
Chapter IX Diseases of the circulatory system
0.899 0.101 0.000
J95-J99 Other diseases of the respiratory system
0.894 0.106 0.000
M06 Other rheumatoid arthritis
0.888 0.112 0.000
M25.57 Pain in joint (Ankle and foot)
0.884 0.116 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.883 0.117 0.000
M80-M85 Disorders of bone density and structure
0.880 0.120 0.000
R79 Other abnormal findings of blood chemistry
0.879 0.121 0.000
J20-J22 Other acute lower respiratory infections
0.879 0.121 0.000
C15-C26 Malignant neoplasms of digestive organs
0.874 0.126 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.872 0.128 0.000
M25.56 Pain in joint (Lower leg)
0.867 0.133 0.000
J93 Pneumothorax
0.862 0.138 0.000
F41 Other anxiety disorders
0.859 0.141 0.000
Chapter XX External causes of morbidity and mortality
0.859 0.141 0.000
M25.4 Effusion of joint
0.853 0.147 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.850 0.150 0.000
M06.9 Rheumatoid arthritis, unspecified
0.850 0.150 0.000
M20.3 Other deformity of hallux (acquired)
0.849 0.151 0.000
I30-I52 Other forms of heart disease
0.845 0.155 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.841 0.159 0.000
M23 Internal derangement of knee
0.839 0.161 0.000
C15 Malignant neoplasm of oesophagus
0.838 0.162 0.000
R18 Ascites
0.837 0.163 0.000
J09-J18 Influenza and pneumonia
0.835 0.165 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.829 0.171 0.000
J98 Other respiratory disorders
0.827 0.173 0.000
M20.4 Other hammer toe(s) (acquired)
0.823 0.177 0.000
M24 Other specific joint derangements
0.821 0.179 0.000
F41.9 Anxiety disorder, unspecified
0.820 0.180 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.819 0.181 0.000
M20.2 Hallux rigidus
0.811 0.189 0.000
M45-M49 Spondylopathies
0.806 0.194 0.000
M20.5 Other deformities of toe(s) (acquired)
0.806 0.194 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.804 0.196 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.803 0.197 0.000
C64-C68 Malignant neoplasms of urinary tract
0.801 0.199 0.000
J22 Unspecified acute lower respiratory infection
0.794 0.206 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.792 0.208 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.789 0.211 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.786 0.214 0.000
M21 Other acquired deformities of limbs
0.780 0.220 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.779 0.221 0.000
M40-M43 Deforming dorsopathies
0.778 0.222 0.000
J60-J70 Lung diseases due to external agents
0.777 0.223 0.000
I50 Heart failure
0.776 0.224 0.000
C15.5 Lower third of oesophagus
0.775 0.225 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.774 0.226 0.000
J84 Other interstitial pulmonary diseases
0.767 0.233 0.000
M81 Osteoporosis without pathological fracture
0.767 0.233 0.000
F80-F89 Disorders of psychological development
0.762 0.238 0.000
J40-J47 Chronic lower respiratory diseases
0.762 0.238 0.000
F45 Somatoform disorders
0.759 0.241 0.000
J93.1 Other spontaneous pneumothorax
0.758 0.242 0.000
M07 Psoriatic and enteropathic arthropathies
0.757 0.243 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.757 0.243 0.000
M23.3 Other meniscus derangements
0.756 0.244 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.756 0.244 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.756 0.244 0.000
Chapter VIII Diseases of the ear and mastoid process
0.755 0.245 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.752 0.248 0.000
Chapter VII Diseases of the eye and adnexa
0.752 0.248 0.000
R19.4 Change in bowel habit
0.749 0.251 0.000
J98.4 Other disorders of lung
0.747 0.253 0.000
I10-I15 Hypertensive diseases
0.743 0.257 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.741 0.259 0.000
M25.7 Osteophyte
0.740 0.260 0.000
C15.9 Oesophagus, unspecified
0.738 0.262 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.738 0.262 0.000
I80 Phlebitis and thrombophlebitis
0.737 0.263 0.000
Chapter XI Diseases of the digestive system
0.736 0.264 0.000
I60-I69 Cerebrovascular diseases
0.736 0.264 0.000
R47-R49 Symptoms and signs involving speech and voice
0.735 0.265 0.000
Y95 Nosocomial condition
0.734 0.266 0.000
M86-M90 Other osteopathies
0.732 0.268 0.000
R19.5 Other fecal abnormalities
0.732 0.268 0.000
C51-C58 Malignant neoplasms of female genital organs
0.727 0.273 0.000
C67 Malignant neoplasm of bladder
0.727 0.273 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.724 0.276 0.000
K30 Dyspepsia
0.722 0.278 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.721 0.279 0.000
F03 Unspecified dementia
0.720 0.280 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.720 0.280 0.000
J18 Pneumonia, organism unspecified
0.719 0.281 0.000
M25.46 Effusion of joint (Lower leg)
0.718 0.282 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.718 0.282 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M31 Other necrotising vasculopathies
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R04 Haemorrhage from respiratory passages
0.715 0.285 0.000
M20.0 Deformity of finger(s)
0.714 0.285 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.713 0.287 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.712 0.288 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.712 0.288 0.000
I51 Complications and ill-defined descriptions of heart disease
0.712 0.288 0.000
I34 Nonrheumatic mitral valve disorders
0.711 0.289 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.711 0.289 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.711 0.289 0.000
S20-S29 Injuries to the thorax
0.710 0.290 0.000
M05 Seropositive rheumatoid arthritis
0.708 0.292 0.000
M13 Other arthritis
0.707 0.293 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.705 0.295 0.000
F99-F99 Unspecified mental disorder
0.704 0.296 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.704 0.296 0.000
F70-F79 Mental retardation
0.704 0.296 0.000
F60-F69 Disorders of adult personality and behaviour
0.704 0.296 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.704 0.296 0.000
Chapter XXII Codes for special purposes
0.703 0.297 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.703 0.297 0.000
M23.8 Other internal derangements of knee
0.702 0.298 0.000
M25.9 Joint disorder, unspecified
0.701 0.299 0.000
M25.8 Other specified joint disorders
0.701 0.299 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.701 0.299 0.000
M25.3 Other instability of joint
0.701 0.299 0.000
M25.2 Flail joint
0.701 0.299 0.000
M25.1 Fistula of joint
0.701 0.299 0.000
M25.0 Haemarthrosis
0.701 0.299 0.000
F43 Reaction to severe stress, and adjustment disorders
0.701 0.299 0.000
M22 Disorders of patella
0.700 0.300 0.000
R73 Elevated blood glucose level
0.699 0.301 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.698 0.302 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.697 0.303 0.000
J98.1 Pulmonary collapse
0.696 0.304 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.696 0.304 0.000
I50.0 Congestive heart failure
0.696 0.304 0.000
J94 Other pleural conditions
0.693 0.307 0.000
M24.1 Other articular cartilage disorders
0.692 0.307 0.000
M25.47 Effusion of joint (Ankle and foot)
0.692 0.308 0.000
M65-M68 Disorders of synovium and tendon
0.690 0.310 0.000
F00 Dementia in Alzheimer's disease
0.687 0.313 0.000
I38 Endocarditis, valve unspecified
0.687 0.313 0.000
J93.9 Pneumothorax, unspecified
0.686 0.313 0.000
M81.9 Osteoporosis, unspecified
0.686 0.314 0.000
C16 Malignant neoplasm of stomach
0.685 0.315 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.681 0.319 0.000
M25.54 Pain in joint (Hand)
0.679 0.321 0.000
D00-D09 In situ neoplasms
0.678 0.322 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.678 0.322 0.000
J81 Pulmonary oedema
0.675 0.325 0.000
M14 Arthropathies in other diseases classified elsewhere
0.674 0.325 0.000
M12 Other specific arthropathies
0.674 0.325 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.674 0.325 0.000
M08 Juvenile arthritis
0.674 0.325 0.000
I50.9 Heart failure, unspecified
0.674 0.326 0.000
M85 Other disorders of bone density and structure
0.674 0.326 0.000
M25.59 Pain in joint (Site unspecified)
0.672 0.327 0.000
M25.58 Pain in joint (Other)
0.672 0.327 0.000
M25.52 Pain in joint (Upper arm)
0.672 0.327 0.000
M25.50 Pain in joint (Multiple sites)
0.672 0.327 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.671 0.328 0.000
W00-W19 Falls
0.671 0.329 0.000
I42 Cardiomyopathy
0.670 0.329 0.000
J80 Adult respiratory distress syndrome
0.669 0.330 0.000
M35 Other systemic involvement of connective tissue
0.669 0.331 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.669 0.331 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.669 0.331 0.000
R77 Other abnormalities of plasma proteins
0.669 0.331 0.000
R76 Other abnormal immunological findings in serum
0.669 0.331 0.000
R74 Abnormal serum enzyme levels
0.669 0.331 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.669 0.331 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.669 0.331 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.669 0.331 0.000
R71 Abnormality of red blood cells
0.669 0.331 0.000
J40 Bronchitis, not specified as acute or chronic
0.668 0.332 0.000
C25 Malignant neoplasm of pancreas
0.667 0.333 0.000
F30-F39 Mood [affective] disorders
0.664 0.336 0.000
R04.2 Haemoptysis
0.664 0.336 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.663 0.337 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.663 0.337 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.663 0.337 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.663 0.337 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.663 0.337 0.000
V10-V19 Pedal cyclist injured in transport accident
0.661 0.338 0.000
F48 Other neurotic disorders
0.661 0.339 0.000
F44 Dissociative [conversion] disorders
0.661 0.339 0.000
F42 Obsessive-compulsive disorder
0.661 0.339 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.659 0.341 0.000
J91 Pleural effusion in conditions classified elsewhere
0.657 0.342 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.656 0.344 0.000
K25 Gastric ulcer
0.656 0.344 0.000
M11 Other crystal arthropathies
0.654 0.346 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.652 0.348 0.000
M47 Spondylosis
0.652 0.348 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.652 0.348 0.000
R06 Abnormalities of breathing
0.651 0.349 0.000
M80 Osteoporosis with pathological fracture
0.651 0.349 0.000
W20-W49 Exposure to inanimate mechanical forces
0.650 0.350 0.000
M25.53 Pain in joint (Forearm)
0.647 0.353 0.000
V80-V89 Other land transport accidents
0.646 0.353 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.644 0.356 0.000
I00-I02 Acute rheumatic fever
0.644 0.356 0.000
J00-J06 Acute upper respiratory infections
0.644 0.356 0.000
X60-X84 Intentional self-harm
0.644 0.356 0.000
F45.8 Other somatoform disorders
0.643 0.357 0.000
I49 Other cardiac arrhythmias
0.643 0.357 0.000
S70-S79 Injuries to the hip and thigh
0.643 0.357 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.641 0.359 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.641 0.359 0.000
J96 Respiratory failure, not elsewhere classified
0.641 0.359 0.000
M06.8 Other specified rheumatoid arthritis
0.636 0.363 0.000
M06.4 Inflammatory polyarthropathy
0.636 0.363 0.000
M06.3 Rheumatoid nodule
0.636 0.363 0.000
M06.2 Rheumatoid bursitis
0.636 0.363 0.000
M06.1 Adult-onset Still's disease
0.636 0.363 0.000
M06.0 Seronegative rheumatoid arthritis
0.636 0.363 0.000
S60-S69 Injuries to the wrist and hand
0.635 0.365 0.000
I12 Hypertensive renal disease
0.634 0.366 0.000
I30 Acute pericarditis
0.633 0.367 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.633 0.367 0.000
M84 Disorders of continuity of bone
0.631 0.369 0.000
M83 Adult osteomalacia
0.631 0.369 0.000
M82 Osteoporosis in diseases classified elsewhere
0.631 0.369 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.630 0.369 0.000
R79.0 Abnormal level of blood mineral
0.630 0.369 0.000
J21 Acute bronchiolitis
0.630 0.370 0.000
J20 Acute bronchitis
0.630 0.370 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.628 0.372 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.627 0.373 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.627 0.373 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.627 0.373 0.000
C21 Malignant neoplasm of anus and anal canal
0.627 0.373 0.000
C17 Malignant neoplasm of small intestine
0.627 0.373 0.000
C23 Malignant neoplasm of gallbladder
0.627 0.373 0.000
M07.3 Other psoriatic arthropathies
0.626 0.374 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.625 0.375 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.625 0.375 0.000
F02 Dementia in other diseases classified elsewhere
0.625 0.375 0.000
F01 Vascular dementia
0.625 0.375 0.000
F09 Unspecified organic or symptomatic mental disorder
0.625 0.375 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.625 0.375 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.625 0.375 0.000
R06.0 Dyspnoea
0.624 0.376 0.000
R25 Abnormal involuntary movements
0.623 0.377 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.623 0.377 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.623 0.377 0.000
I51.8 Other ill-defined heart diseases
0.623 0.377 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.622 0.377 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.622 0.378 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.622 0.378 0.000
F10.1 Harmful use
0.621 0.379 0.000
D10-D36 Benign neoplasms
0.619 0.381 0.000
M25.51 Pain in joint (Shoulder region)
0.619 0.381 0.000
J69 Pneumonitis due to solids and liquids
0.619 0.381 0.000
J93.8 Other pneumothorax
0.618 0.382 0.000
J93.0 Spontaneous tension pneumothorax
0.618 0.382 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.618 0.382 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.618 0.382 0.000
R29.6 Tendency to fall, not elsewhere classified
0.617 0.383 0.000
I46 Cardiac arrest
0.617 0.383 0.000
J47 Bronchiectasis
0.617 0.383 0.000
M46 Other inflammatory spondylopathies
0.616 0.384 0.000
F41.8 Other specified anxiety disorders
0.616 0.384 0.000
F41.3 Other mixed anxiety disorders
0.616 0.384 0.000
F41.1 Generalised anxiety disorder
0.616 0.384 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.616 0.384 0.000
Y35-Y36 Legal intervention and operations of war
0.616 0.384 0.000
Y10-Y34 Event of undetermined intent
0.616 0.384 0.000
Y00-Y09 Assault
0.616 0.384 0.000
X85-X99 Assault
0.616 0.384 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.616 0.384 0.000
X50-X57 Overexertion, travel and privation
0.616 0.384 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.616 0.384 0.000
X30-X39 Exposure to forces of nature
0.616 0.384 0.000
X20-X29 Contact with venomous animals and plants
0.616 0.384 0.000
X10-X19 Contact with heat and hot substances
0.616 0.384 0.000
X00-X09 Exposure to smoke, fire and flames
0.616 0.384 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.616 0.384 0.000
W75-W84 Other accidental threats to breathing
0.616 0.384 0.000
W65-W74 Accidental drowning and submersion
0.616 0.384 0.000
W50-W64 Exposure to animate mechanical forces
0.616 0.384 0.000
V98-V99 Other and unspecified transport accidents
0.616 0.384 0.000
V95-V97 Air and space transport accidents
0.616 0.384 0.000
V90-V94 Water transport accidents
0.616 0.384 0.000
V70-V79 Bus occupant injured in transport accident
0.616 0.384 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.616 0.384 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.616 0.384 0.000
V40-V49 Car occupant injured in transport accident
0.616 0.384 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.616 0.384 0.000
V20-V29 Motorcycle rider injured in transport accident
0.616 0.384 0.000
V01-V09 Pedestrian injured in transport accident
0.616 0.384 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.616 0.384 0.000
H02 Other disorders of eyelid
0.616 0.384 0.000
M23.4 Loose body in knee
0.615 0.385 0.000
D45 Polycythaemia vera
0.613 0.387 0.000
M25.77 Osteophyte (Ankle and foot)
0.612 0.388 0.000
M25.49 Effusion of joint (Site unspecified)
0.611 0.388 0.000
M25.48 Effusion of joint (Other)
0.611 0.388 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.611 0.388 0.000
M25.44 Effusion of joint (Hand)
0.611 0.388 0.000
M25.43 Effusion of joint (Forearm)
0.611 0.388 0.000
M25.42 Effusion of joint (Upper arm)
0.611 0.388 0.000
M25.41 Effusion of joint (Shoulder region)
0.611 0.388 0.000
M25.40 Effusion of joint (Multiple sites)
0.611 0.388 0.000
H90-H95 Other disorders of ear
0.610 0.390 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.609 0.390 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.609 0.390 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.609 0.390 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.609 0.390 0.000
R27 Other lack of coordination
0.609 0.390 0.000
C56 Malignant neoplasm of ovary
0.609 0.391 0.000
H53-H54 Visual disturbances and blindness
0.606 0.394 0.000
I63 Cerebral infarction
0.606 0.394 0.000
I52 Other heart disorders in diseases classified elsewhere
0.606 0.394 0.000
I48 Atrial fibrillation and flutter
0.606 0.394 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.606 0.394 0.000
I41 Myocarditis in diseases classified elsewhere
0.606 0.394 0.000
I40 Acute myocarditis
0.606 0.394 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.606 0.394 0.000
I37 Pulmonary valve disorders
0.606 0.394 0.000
I36 Nonrheumatic tricuspid valve disorders
0.606 0.394 0.000
I33 Acute and subacute endocarditis
0.606 0.394 0.000
I32 Pericarditis in diseases classified elsewhere
0.606 0.394 0.000
F80 Specific developmental disorders of speech and language
0.605 0.395 0.000
M23.9 Internal derangement of knee, unspecified
0.601 0.398 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.601 0.398 0.000
M23.5 Chronic instability of knee
0.601 0.398 0.000
M23.1 Discoid meniscus (congenital)
0.601 0.398 0.000
M23.0 Cystic meniscus
0.601 0.398 0.000
J18.9 Pneumonia, unspecified
0.601 0.398 0.000
S00-S09 Injuries to the head
0.601 0.399 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.601 0.399 0.000
C15.8 Overlapping lesion of oesophagus
0.600 0.399 0.000
C15.4 Middle third of oesophagus
0.600 0.399 0.000
C15.3 Upper third of oesophagus
0.600 0.399 0.000
C15.2 Abdominal part of oesophagus
0.600 0.399 0.000
C15.1 Thoracic part of oesophagus
0.600 0.399 0.000
C15.0 Cervical part of oesophagus
0.600 0.399 0.000
K85 Acute pancreatitis
0.601 0.399 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.599 0.401 0.000
J17 Pneumonia in diseases classified elsewhere
0.599 0.401 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.599 0.401 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.599 0.401 0.000
J12 Viral pneumonia, not elsewhere classified
0.599 0.401 0.000
J11 Influenza, virus not identified
0.599 0.401 0.000
J10 Influenza due to identified influenza virus
0.599 0.401 0.000
J14 Pneumonia due to Haemophilus influenzae
0.599 0.401 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.599 0.401 0.000
J09 Influenza due to certain identified influenza virus
0.599 0.401 0.000
R04.0 Epistaxis
0.598 0.402 0.000
R50-R69 General symptoms and signs
0.597 0.403 0.000
K82 Other diseases of gallbladder
0.596 0.404 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.596 0.404 0.000
C67.9 Bladder, unspecified
0.595 0.405 0.000
L60-L75 Disorders of skin appendages
0.595 0.405 0.000
C50-C50 Malignant neoplasm of breast
0.594 0.406 0.000
K26 Duodenal ulcer
0.594 0.406 0.000
I34.0 Mitral (valve) insufficiency
0.594 0.406 0.000
H55-H59 Other disorders of eye and adnexa
0.593 0.407 0.000
J18.1 Lobar pneumonia, unspecified
0.593 0.407 0.000
J98.9 Respiratory disorder, unspecified
0.593 0.407 0.000
J98.8 Other specified respiratory disorders
0.593 0.407 0.000
J98.6 Disorders of diaphragm
0.593 0.407 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.593 0.407 0.000
J98.3 Compensatory emphysema
0.593 0.407 0.000
J98.2 Interstitial emphysema
0.593 0.407 0.000
M41 Scoliosis
0.592 0.408 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.592 0.408 0.000
M43 Other deforming dorsopathies
0.590 0.410 0.000
C67.4 Posterior wall of bladder
0.590 0.410 0.000
M24.9 Joint derangement, unspecified
0.588 0.411 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.588 0.411 0.000
M24.7 Protrusio acetabuli
0.588 0.411 0.000
M24.6 Ankylosis of joint
0.588 0.411 0.000
M24.5 Contracture of joint
0.588 0.411 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.588 0.411 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.588 0.411 0.000
M24.2 Disorder of ligament
0.588 0.411 0.000
M24.0 Loose body in joint
0.588 0.411 0.000
K25.7 Chronic without haemorrhage or perforation
0.588 0.412 0.000
R19.6 Halitosis
0.587 0.412 0.000
R19.3 Abdominal rigidity
0.587 0.412 0.000
R19.2 Visible peristalsis
0.587 0.412 0.000
R19.1 Abnormal bowel sounds
0.587 0.412 0.000
C67.5 Bladder neck
0.587 0.413 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.587 0.413 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.586 0.414 0.000
I86 Varicose veins of other sites
0.585 0.415 0.000
C22.1 Intrahepatic bile duct carcinoma
0.583 0.417 0.000
M15-M19 Arthrosis
0.583 0.417 0.000
F40 Phobic anxiety disorders
0.579 0.421 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.579 0.421 0.000
M49 Spondylopathies in diseases classified elsewhere
0.578 0.422 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.577 0.423 0.000
M48 Other spondylopathies
0.577 0.423 0.000
S90-S99 Injuries to the ankle and foot
0.576 0.424 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.576 0.424 0.000
M99 Biomechanical lesions, not elsewhere classified
0.575 0.424 0.000
C43 Malignant melanoma of skin
0.575 0.425 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.575 0.425 0.000
C66 Malignant neoplasm of ureter
0.575 0.425 0.000
C65 Malignant neoplasm of renal pelvis
0.575 0.425 0.000
D46 Myelodysplastic syndromes
0.574 0.426 0.000
F05.9 Delirium, unspecified
0.574 0.426 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.574 0.426 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.574 0.426 0.000
R47 Speech disturbances, not elsewhere classified
0.572 0.428 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.571 0.429 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.570 0.430 0.000
I61 Intracerebral haemorrhage
0.570 0.430 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.570 0.430 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.568 0.432 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.568 0.432 0.000
Q80-Q89 Other congenital malformations
0.568 0.432 0.000
Q60-Q64 Congenital malformations of the urinary system
0.568 0.432 0.000
Q50-Q56 Congenital malformations of genital organs
0.568 0.432 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.568 0.432 0.000
Q35-Q37 Cleft lip and cleft palate
0.568 0.432 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.568 0.432 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.568 0.432 0.000
Q00-Q07 Congenital malformations of the nervous system
0.568 0.432 0.000
R63 Symptoms and signs concerning food and fluid intake
0.568 0.432 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.567 0.432 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.566 0.434 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.566 0.434 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.566 0.434 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.566 0.434 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.566 0.434 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.566 0.434 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.566 0.434 0.000
F11 Mental and behavioural disorders due to use of opioids
0.566 0.434 0.000
H80-H83 Diseases of inner ear
0.565 0.435 0.000
I31 Other diseases of pericardium
0.565 0.435 0.000
M10 Gout
0.564 0.435 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.564 0.436 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.564 0.436 0.000
Y98 Lifestyle-related condition
0.564 0.436 0.000
Y97 Environmental-pollution-related condition
0.564 0.436 0.000
Y96 Work-related condition
0.564 0.436 0.000
L84 Corns and callosities
0.563 0.437 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.562 0.438 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.562 0.438 0.000
R26 Abnormalities of gait and mobility
0.561 0.439 0.000
I67 Other cerebrovascular diseases
0.561 0.439 0.000
K82.8 Other specified diseases of gallbladder
0.561 0.439 0.000
C34 Malignant neoplasm of bronchus and lung
0.560 0.440 0.000
M45 Ankylosing spondylitis
0.560 0.440 0.000
M88 Paget's disease of bone [osteitis deformans]
0.560 0.440 0.000
R15 Faecal incontinence
0.560 0.440 0.000
M21.9 Acquired deformity of limb, unspecified
0.559 0.441 0.000
M21.8 Other specified acquired deformities of limbs
0.559 0.441 0.000
M21.7 Unequal limb length (acquired)
0.559 0.441 0.000
M21.6 Other acquired deformities of ankle and foot
0.559 0.441 0.000
M21.4 Flat foot [pes planus] (acquired)
0.559 0.441 0.000
M21.3 Wrist or foot drop (acquired)
0.559 0.441 0.000
M21.2 Flexion deformity
0.559 0.441 0.000
M21.1 Varus deformity, not elsewhere classified
0.559 0.441 0.000
M21.0 Valgus deformity, not elsewhere classified
0.559 0.441 0.000
I69 Sequelae of cerebrovascular disease
0.559 0.441 0.000
T79-T79 Certain early complications of trauma
0.558 0.441 0.000
T33-T35 Frostbite
0.558 0.441 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.558 0.441 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.558 0.441 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.558 0.441 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.558 0.441 0.000
T00-T07 Injuries involving multiple body regions
0.558 0.441 0.000
S10-S19 Injuries to the neck
0.558 0.441 0.000
M42 Spinal osteochondrosis
0.558 0.442 0.000
M40 Kyphosis and lordosis
0.558 0.442 0.000
R63.4 Abnormal weight loss
0.558 0.442 0.000
J70 Respiratory conditions due to other external agents
0.557 0.443 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.557 0.443 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.557 0.443 0.000
J66 Airway disease due to specific organic dust
0.557 0.443 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.557 0.443 0.000
J62 Pneumoconiosis due to dust containing silica
0.557 0.443 0.000
J65 Pneumoconiosis associated with tuberculosis
0.557 0.443 0.000
J64 Unspecified pneumoconiosis
0.557 0.443 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.557 0.443 0.000
J60 Coalworker's pneumoconiosis
0.557 0.443 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.557 0.443 0.000
C18 Malignant neoplasm of colon
0.557 0.443 0.000
R87 Abnormal findings in specimens from female genital organs
0.556 0.444 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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