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Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61913987
log Bayes Factor = 14.099
Chromosome 11   position 130,522,894  (GRCh37) Explore rs61913987 on Ensembl!
Variant rs61913987 is part of Cluster X0146

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.989 0.011 0.000
D10-D36 Benign neoplasms
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.988 0.012 0.000
F30-F39 Mood [affective] disorders
0.980 0.020 0.000
N10-N16 Renal tubulo-interstitial diseases
0.979 0.021 0.000
H30-H36 Disorders of choroid and retina
0.978 0.022 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.976 0.024 0.000
I44 Atrioventricular and left bundle-branch block
0.975 0.025 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.974 0.026 0.000
H35 Other retinal disorders
0.970 0.030 0.000
N13 Obstructive and reflux uropathy
0.969 0.031 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.969 0.031 0.000
F41 Other anxiety disorders
0.957 0.043 0.000
Chapter VIII Diseases of the ear and mastoid process
0.954 0.046 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.954 0.046 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.953 0.047 0.000
Chapter VI Diseases of the nervous system
0.953 0.047 0.000
N40-N51 Diseases of male genital organs
0.947 0.053 0.000
F32 Depressive episode
0.944 0.056 0.000
D12.3 Transverse colon
0.941 0.059 0.000
F41.9 Anxiety disorder, unspecified
0.941 0.059 0.000
H53-H54 Visual disturbances and blindness
0.937 0.063 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.935 0.065 0.000
S60-S69 Injuries to the wrist and hand
0.935 0.065 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.934 0.066 0.000
D12.6 Colon, unspecified
0.933 0.067 0.000
H35.3 Degeneration of macula and posterior pole
0.932 0.068 0.000
C64-C68 Malignant neoplasms of urinary tract
0.931 0.069 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.930 0.070 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.927 0.073 0.000
I50 Heart failure
0.925 0.075 0.000
N00-N08 Glomerular diseases
0.918 0.082 0.000
G90-G99 Other disorders of the nervous system
0.914 0.086 0.000
I77 Other disorders of arteries and arterioles
0.913 0.087 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.912 0.088 0.000
H35.8 Other specified retinal disorders
0.907 0.093 0.000
I35 Nonrheumatic aortic valve disorders
0.902 0.098 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.901 0.099 0.000
I50.0 Congestive heart failure
0.900 0.100 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.900 0.100 0.000
F43 Reaction to severe stress, and adjustment disorders
0.897 0.103 0.000
I73 Other peripheral vascular diseases
0.891 0.109 0.000
H65-H75 Diseases of middle ear and mastoid
0.891 0.109 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.889 0.111 0.000
I77.1 Stricture of artery
0.886 0.114 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.882 0.118 0.000
I51 Complications and ill-defined descriptions of heart disease
0.882 0.118 0.000
F32.9 Depressive episode, unspecified
0.881 0.119 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.880 0.120 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.880 0.120 0.000
N60-N64 Disorders of breast
0.880 0.120 0.000
R20 Disturbances of skin sensation
0.879 0.121 0.000
I60-I69 Cerebrovascular diseases
0.878 0.122 0.000
H90-H95 Other disorders of ear
0.876 0.124 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.876 0.124 0.000
S20-S29 Injuries to the thorax
0.872 0.128 0.000
I27 Other pulmonary heart diseases
0.871 0.129 0.000
D50-D53 Nutritional anaemias
0.870 0.130 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.870 0.130 0.000
D12.5 Sigmoid colon
0.867 0.133 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.865 0.135 0.000
I05-I09 Chronic rheumatic heart diseases
0.865 0.135 0.000
G70-G73 Diseases of myoneural junction and muscle
0.863 0.137 0.000
H53 Visual disturbances
0.861 0.139 0.000
D23 Other benign neoplasms of skin
0.860 0.140 0.000
I44.1 Atrioventricular block, second degree
0.859 0.141 0.000
N41 Inflammatory diseases of prostate
0.859 0.141 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.858 0.142 0.000
H55-H59 Other disorders of eye and adnexa
0.857 0.143 0.000
D32 Benign neoplasm of meninges
0.857 0.143 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.856 0.144 0.000
I44.2 Atrioventricular block, complete
0.855 0.145 0.000
N17-N19 Renal failure
0.853 0.147 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.851 0.149 0.000
H91 Other hearing loss
0.847 0.153 0.000
I69 Sequelae of cerebrovascular disease
0.844 0.156 0.000
I73.9 Peripheral vascular disease, unspecified
0.843 0.157 0.000
I26 Pulmonary embolism
0.843 0.157 0.000
N13.3 Other and unspecified hydronephrosis
0.841 0.159 0.000
D34 Benign neoplasm of thyroid gland
0.840 0.160 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.836 0.164 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.835 0.165 0.000
I44.0 Atrioventricular block, first degree
0.834 0.166 0.000
H02 Other disorders of eyelid
0.833 0.167 0.000
I51.7 Cardiomegaly
0.833 0.167 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.831 0.169 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.831 0.169 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.831 0.169 0.000
I33 Acute and subacute endocarditis
0.830 0.170 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.828 0.172 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.827 0.173 0.000
D23.1 Skin of eyelid, including canthus
0.826 0.174 0.000
H91.9 Hearing loss, unspecified
0.826 0.174 0.000
Chapter XXII Codes for special purposes
0.824 0.176 0.000
H02.4 Ptosis of eyelid
0.822 0.178 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.822 0.178 0.000
I49 Other cardiac arrhythmias
0.819 0.181 0.000
T90 Sequelae of injuries of head
0.819 0.181 0.000
R23 Other skin changes
0.819 0.181 0.000
N48 Other disorders of penis
0.819 0.181 0.000
C67 Malignant neoplasm of bladder
0.818 0.182 0.000
D50 Iron deficiency anaemia
0.818 0.182 0.000
R47-R49 Symptoms and signs involving speech and voice
0.816 0.184 0.000
R45 Symptoms and signs involving emotional state
0.816 0.184 0.000
G93 Other disorders of brain
0.815 0.185 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.815 0.185 0.000
G30-G32 Other degenerative diseases of the nervous system
0.815 0.185 0.000
F22 Persistent delusional disorders
0.813 0.187 0.000
F31 Bipolar affective disorder
0.813 0.187 0.000
N18 Chronic renal failure
0.812 0.188 0.000
C66 Malignant neoplasm of ureter
0.812 0.188 0.000
I30 Acute pericarditis
0.812 0.188 0.000
N13.8 Other obstructive and reflux uropathy
0.808 0.192 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.807 0.193 0.000
R87 Abnormal findings in specimens from female genital organs
0.807 0.193 0.000
H65 Nonsuppurative otitis media
0.806 0.194 0.000
F33 Recurrent depressive disorder
0.805 0.195 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.805 0.195 0.000
N02 Recurrent and persistent haematuria
0.805 0.195 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.804 0.196 0.000
N30-N39 Other diseases of urinary system
0.804 0.196 0.000
N45 Orchitis and epididymitis
0.801 0.199 0.000
C43 Malignant melanoma of skin
0.801 0.199 0.000
M45-M49 Spondylopathies
0.799 0.201 0.000
N60 Benign mammary dysplasia
0.798 0.202 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.798 0.202 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.797 0.203 0.000
N20-N23 Urolithiasis
0.795 0.205 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.795 0.205 0.000
T98 Sequelae of other and unspecified effects of external causes
0.793 0.207 0.000
H31 Other disorders of choroid
0.793 0.207 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.791 0.209 0.000
H35.6 Retinal haemorrhage
0.789 0.211 0.000
I35.0 Aortic (valve) stenosis
0.789 0.211 0.000
N46 Male infertility
0.789 0.211 0.000
S67 Crushing injury of wrist and hand
0.786 0.214 0.000
F45 Somatoform disorders
0.783 0.217 0.000
H54 Blindness and low vision
0.783 0.217 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.782 0.218 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.781 0.219 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.779 0.221 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.777 0.223 0.000
S69 Other and unspecified injuries of wrist and hand
0.776 0.224 0.000
I44.7 Left bundle-branch block, unspecified
0.776 0.224 0.000
R26 Abnormalities of gait and mobility
0.775 0.225 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.774 0.226 0.000
D26 Other benign neoplasms of uterus
0.774 0.226 0.000
N41.1 Chronic prostatitis
0.770 0.230 0.000
D16 Benign neoplasm of bone and articular cartilage
0.769 0.231 0.000
I42 Cardiomyopathy
0.768 0.232 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.768 0.232 0.000
R45.8 Other symptoms and signs involving emotional state
0.767 0.233 0.000
N03 Chronic nephritic syndrome
0.766 0.234 0.000
T79-T79 Certain early complications of trauma
0.765 0.235 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.764 0.235 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.764 0.236 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.764 0.236 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.762 0.238 0.000
H53.8 Other visual disturbances
0.762 0.238 0.000
F23 Acute and transient psychotic disorders
0.761 0.239 0.000
D48.5 Skin
0.760 0.240 0.000
T92 Sequelae of injuries of upper limb
0.759 0.241 0.000
I34 Nonrheumatic mitral valve disorders
0.758 0.242 0.000
S68 Traumatic amputation of wrist and hand
0.758 0.242 0.000
F20 Schizophrenia
0.758 0.242 0.000
N35 Urethral stricture
0.758 0.242 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.758 0.242 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.757 0.243 0.000
G72 Other myopathies
0.755 0.245 0.000
H21 Other disorders of iris and ciliary body
0.755 0.245 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.755 0.245 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.755 0.245 0.000
F80-F89 Disorders of psychological development
0.753 0.246 0.000
R27 Other lack of coordination
0.753 0.247 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.751 0.249 0.000
S10-S19 Injuries to the neck
0.751 0.249 0.000
F43.2 Adjustment disorders
0.750 0.249 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.750 0.250 0.000
T00-T07 Injuries involving multiple body regions
0.748 0.252 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.747 0.253 0.000
H57 Other disorders of eye and adnexa
0.746 0.253 0.000
I36 Nonrheumatic tricuspid valve disorders
0.746 0.254 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.746 0.254 0.000
D32.9 Meninges, unspecified
0.746 0.254 0.000
R47 Speech disturbances, not elsewhere classified
0.745 0.255 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.745 0.255 0.000
I47 Paroxysmal tachycardia
0.745 0.255 0.000
F60-F69 Disorders of adult personality and behaviour
0.745 0.255 0.000
D48.1 Connective and other soft tissue
0.745 0.255 0.000
S27 Injury of other and unspecified intrathoracic organs
0.744 0.256 0.000
I27.0 Primary pulmonary hypertension
0.744 0.256 0.000
G95 Other diseases of spinal cord
0.744 0.256 0.000
M47 Spondylosis
0.743 0.257 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.741 0.259 0.000
I69.3 Sequelae of cerebral infarction
0.741 0.259 0.000
I27.9 Pulmonary heart disease, unspecified
0.740 0.259 0.000
F43.0 Acute stress reaction
0.740 0.260 0.000
H35.7 Separation of retinal layers
0.740 0.260 0.000
I05 Rheumatic mitral valve diseases
0.738 0.262 0.000
D48.7 Other specified sites
0.737 0.263 0.000
H35.5 Hereditary retinal dystrophy
0.735 0.265 0.000
G91 Hydrocephalus
0.734 0.266 0.000
I07 Rheumatic tricuspid valve diseases
0.734 0.266 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.733 0.267 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.733 0.267 0.000
N60.1 Diffuse cystic mastopathy
0.733 0.267 0.000
H35.9 Retinal disorder, unspecified
0.732 0.268 0.000
F22.0 Delusional disorder
0.731 0.269 0.000
H72 Perforation of tympanic membrane
0.731 0.269 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.730 0.269 0.000
D13.1 Stomach
0.730 0.270 0.000
S90-S99 Injuries to the ankle and foot
0.728 0.272 0.000
F40 Phobic anxiety disorders
0.728 0.272 0.000
N10 Acute tubulo-interstitial nephritis
0.728 0.272 0.000
H18 Other disorders of cornea
0.728 0.272 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.728 0.272 0.000
M80-M85 Disorders of bone density and structure
0.727 0.273 0.000
I44.6 Other and unspecified fascicular block
0.726 0.273 0.000
R87.6 Abnormal cytological findings
0.726 0.274 0.000
N35.9 Urethral stricture, unspecified
0.725 0.275 0.000
M47.9 Spondylosis, unspecified
0.724 0.276 0.000
I35.8 Other aortic valve disorders
0.723 0.277 0.000
N13.6 Pyonephrosis
0.723 0.277 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.723 0.277 0.000
O60-O75 Complications of labour and delivery
0.722 0.278 0.000
S20 Superficial injury of thorax
0.721 0.278 0.000
N18.9 Chronic renal failure, unspecified
0.721 0.279 0.000
D48.0 Bone and articular cartilage
0.721 0.279 0.000
R41.0 Disorientation, unspecified
0.720 0.280 0.000
I78 Diseases of capillaries
0.720 0.280 0.000
G70 Myasthenia gravis and other myoneural disorders
0.718 0.282 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.717 0.283 0.000
M48 Other spondylopathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
H65.3 Chronic mucoid otitis media
0.717 0.283 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.716 0.284 0.000
F32.0 Mild depressive episode
0.716 0.284 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.716 0.284 0.000
H66 Suppurative and unspecified otitis media
0.715 0.285 0.000
S64 Injury of nerves at wrist and hand level
0.712 0.288 0.000
F43.1 Posttraumatic stress disorder
0.712 0.288 0.000
N64 Other disorders of breast
0.711 0.289 0.000
F48 Other neurotic disorders
0.709 0.291 0.000
F44 Dissociative [conversion] disorders
0.709 0.291 0.000
F42 Obsessive-compulsive disorder
0.709 0.291 0.000
I33.0 Acute and subacute infective endocarditis
0.709 0.291 0.000
D31 Benign neoplasm of eye and adnexa
0.708 0.291 0.000
D30 Benign neoplasm of urinary organs
0.708 0.291 0.000
D29 Benign neoplasm of male genital organs
0.708 0.291 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.708 0.291 0.000
D19 Benign neoplasm of mesothelial tissue
0.708 0.291 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.708 0.291 0.000
T33-T35 Frostbite
0.708 0.292 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.708 0.292 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.708 0.292 0.000
I49.4 Other and unspecified premature depolarisation
0.706 0.294 0.000
D13.2 Duodenum
0.706 0.294 0.000
D60-D64 Aplastic and other anaemias
0.705 0.295 0.000
N25-N29 Other disorders of kidney and ureter
0.705 0.295 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.705 0.295 0.000
H53.4 Visual field defects
0.704 0.296 0.000
Chapter I Certain infectious and parasitic diseases
0.704 0.296 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.704 0.296 0.000
F38 Other mood [affective] disorders
0.703 0.297 0.000
F34 Persistent mood [affective] disorders
0.703 0.297 0.000
F30 Manic episode
0.703 0.297 0.000
F39 Unspecified mood [affective] disorder
0.703 0.297 0.000
C71 Malignant neoplasm of brain
0.703 0.297 0.000
N02.9 Unspecified
0.703 0.297 0.000
D12.9 Anus and anal canal
0.702 0.298 0.000
H10-H13 Disorders of conjunctiva
0.702 0.298 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.702 0.298 0.000
N15 Other renal tubulo-interstitial diseases
0.702 0.298 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.702 0.298 0.000
N11 Chronic tubulo-interstitial nephritis
0.702 0.298 0.000
I51.9 Heart disease, unspecified
0.701 0.298 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.701 0.299 0.000
H30 Chorioretinal inflammation
0.701 0.299 0.000
I45 Other conduction disorders
0.701 0.299 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.700 0.300 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.700 0.300 0.000
I44.5 Left posterior fascicular block
0.699 0.301 0.000
I44.4 Left anterior fascicular block
0.699 0.301 0.000
I44.3 Other and unspecified atrioventricular block
0.699 0.301 0.000
D27 Benign neoplasm of ovary
0.699 0.301 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.699 0.301 0.000
D46 Myelodysplastic syndromes
0.699 0.301 0.000
H20 Iridocyclitis
0.698 0.302 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.698 0.302 0.000
F41.2 Mixed anxiety and depressive disorder
0.697 0.303 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.697 0.303 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.697 0.303 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.696 0.304 0.000
I72 Other aneurysm
0.696 0.304 0.000
H35.2 Other proliferative retinopathy
0.696 0.304 0.000
H35.1 Retinopathy of prematurity
0.696 0.304 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.695 0.305 0.000
D12.1 Appendix
0.694 0.305 0.000
H05 Disorders of orbit
0.694 0.305 0.000
H34 Retinal vascular occlusions
0.694 0.306 0.000
G93.6 Cerebral oedema
0.694 0.306 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.693 0.307 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.693 0.307 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.692 0.308 0.000
D36 Benign neoplasm of other and unspecified sites
0.690 0.309 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.691 0.309 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.689 0.311 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.688 0.312 0.000
C09 Malignant neoplasm of tonsil
0.688 0.312 0.000
C34 Malignant neoplasm of bronchus and lung
0.687 0.313 0.000
R25 Abnormal involuntary movements
0.687 0.313 0.000
N23 Unspecified renal colic
0.687 0.313 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.687 0.313 0.000
F41.8 Other specified anxiety disorders
0.686 0.314 0.000
F41.3 Other mixed anxiety disorders
0.686 0.314 0.000
R20.2 Paraesthesia of skin
0.685 0.315 0.000
D10 Benign neoplasm of mouth and pharynx
0.685 0.315 0.000
R94 Abnormal results of function studies
0.685 0.315 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.684 0.316 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.684 0.316 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.684 0.316 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.684 0.316 0.000
I71 Aortic aneurysm and dissection
0.684 0.316 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.684 0.316 0.000
I28 Other diseases of pulmonary vessels
0.683 0.317 0.000
N48.6 Balanitis xerotica obliterans
0.683 0.317 0.000
T90.4 Sequelae of injury of eye and orbit
0.682 0.318 0.000
G90 Disorders of autonomic nervous system
0.682 0.318 0.000
C67.4 Posterior wall of bladder
0.682 0.318 0.000
H02.5 Other disorders affecting eyelid function
0.681 0.319 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.681 0.319 0.000
D23.5 Skin of trunk
0.681 0.319 0.000
T93 Sequelae of injuries of lower limb
0.681 0.319 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.680 0.320 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.680 0.320 0.000
S31 Open wound of abdomen, lower back and pelvis
0.679 0.320 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.679 0.321 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.679 0.321 0.000
F03 Unspecified dementia
0.679 0.321 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.679 0.321 0.000
N44 Torsion of testis
0.679 0.321 0.000
S32 Fracture of lumbar spine and pelvis
0.679 0.321 0.000
R23.8 Other and unspecified skin changes
0.679 0.321 0.000
S60 Superficial injury of wrist and hand
0.678 0.322 0.000
G72.9 Myopathy, unspecified
0.678 0.322 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.678 0.322 0.000
I30.9 Acute pericarditis, unspecified
0.678 0.322 0.000
F32.8 Other depressive episodes
0.677 0.323 0.000
H16 Keratitis
0.676 0.324 0.000
N41.0 Acute prostatitis
0.676 0.324 0.000
N18.5 Chronic kidney disease, stage 5
0.676 0.324 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.676 0.324 0.000
G93.9 Disorder of brain, unspecified
0.676 0.324 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.675 0.325 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.674 0.326 0.000
D45 Polycythaemia vera
0.674 0.326 0.000
N63 Unspecified lump in breast
0.674 0.326 0.000
N04 Nephrotic syndrome
0.673 0.327 0.000
D50.9 Iron deficiency anaemia, unspecified
0.673 0.327 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.672 0.328 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.671 0.329 0.000
N42 Other disorders of prostate
0.671 0.329 0.000
S65 Injury of blood vessels at wrist and hand level
0.670 0.330 0.000
D51 Vitamin B12 deficiency anaemia
0.670 0.330 0.000
T95 Sequelae of burns, corrosions and frostbite
0.669 0.330 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.669 0.330 0.000
T91 Sequelae of injuries of neck and trunk
0.669 0.330 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.669 0.330 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.669 0.330 0.000
I42.9 Cardiomyopathy, unspecified
0.669 0.331 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.669 0.331 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.668 0.332 0.000
I49.8 Other specified cardiac arrhythmias
0.668 0.332 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.668 0.332 0.000
C65 Malignant neoplasm of renal pelvis
0.668 0.332 0.000
C43.4 Malignant melanoma of scalp and neck
0.667 0.333 0.000
D55-D59 Haemolytic anaemias
0.667 0.333 0.000
D21.2 Connective and other soft tissue of lower limb, including hip
0.667 0.333 0.000
I49.9 Cardiac arrhythmia, unspecified
0.667 0.333 0.000
H35.0 Background retinopathy and retinal vascular changes
0.666 0.334 0.000
T90.9 Sequelae of unspecified injury of head
0.666 0.334 0.000
C67.3 Anterior wall of bladder
0.665 0.335 0.000
H53.9 Visual disturbance, unspecified
0.665 0.335 0.000
F25 Schizoaffective disorders
0.665 0.335 0.000
F28 Other nonorganic psychotic disorders
0.665 0.335 0.000
F24 Induced delusional disorder
0.665 0.335 0.000
F21 Schizotypal disorder
0.665 0.335 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.665 0.335 0.000
N48.4 Impotence of organic origin
0.663 0.336 0.000
H80-H83 Diseases of inner ear
0.663 0.337 0.000
S69.9 Unspecified injury of wrist and hand
0.662 0.338 0.000
H54.0 Blindness, both eyes
0.662 0.338 0.000
R23.2 Flushing
0.662 0.338 0.000
D23.0 Skin of lip
0.661 0.339 0.000
S00-S09 Injuries to the head
0.661 0.339 0.000
H31.8 Other specified disorders of choroid
0.661 0.339 0.000
D37.5 Rectum
0.660 0.340 0.000
I70 Atherosclerosis
0.660 0.340 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.660 0.340 0.000
H53.2 Diplopia
0.659 0.340 0.000
I77.8 Other specified disorders of arteries and arterioles
0.659 0.340 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.659 0.341 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.659 0.341 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.658 0.342 0.000
N06 Isolated proteinuria with specified morphological lesion
0.658 0.342 0.000
N05 Unspecified nephritic syndrome
0.658 0.342 0.000
N01 Rapidly progressive nephritic syndrome
0.658 0.342 0.000
N00 Acute nephritic syndrome
0.658 0.342 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.657 0.342 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.657 0.343 0.000
H43-H45 Disorders of vitreous body and globe
0.657 0.343 0.000
N03.9 Unspecified
0.657 0.343 0.000
T98.1 Sequelae of other and unspecified effects of external causes
0.657 0.343 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.656 0.343 0.000
D33.3 Cranial nerves
0.656 0.344 0.000
G96 Other disorders of central nervous system
0.655 0.345 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.655 0.345 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.655 0.345 0.000
G92 Toxic encephalopathy
0.655 0.345 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.655 0.345 0.000
M48.0 Spinal stenosis
0.655 0.345 0.000
I27.2 Other secondary pulmonary hypertension
0.655 0.345 0.000
I77.5 Necrosis of artery
0.654 0.346 0.000
I77.4 Coeliac artery compression syndrome
0.654 0.346 0.000
I77.3 Arterial fibromuscular dysplasia
0.654 0.346 0.000
I77.2 Rupture of artery
0.654 0.346 0.000
I77.0 Arteriovenous fistula, acquired
0.654 0.346 0.000
H53.0 Amblyopia ex anopsia
0.654 0.346 0.000
N13.4 Hydroureter
0.653 0.347 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.653 0.347 0.000
D32.0 Cerebral meninges
0.652 0.348 0.000
S29 Other and unspecified injuries of thorax
0.652 0.348 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.651 0.349 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.650 0.350 0.000
H02.3 Blepharochalasis
0.649 0.350 0.000
H71 Cholesteatoma of middle ear
0.649 0.351 0.000
S70-S79 Injuries to the hip and thigh
0.648 0.352 0.000
H69 Other disorders of Eustachian tube
0.648 0.352 0.000
R90.0 Intracranial space-occupying lesion
0.648 0.352 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.647 0.353 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.647 0.353 0.000
H54.4 Blindness, one eye
0.647 0.353 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.646 0.354 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.646 0.354 0.000
H17 Corneal scars and opacities
0.646 0.354 0.000
H15 Disorders of sclera
0.646 0.354 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.646 0.354 0.000
S62 Fracture at wrist and hand level
0.646 0.354 0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.645 0.355 0.000
D48.6 Breast
0.645 0.355 0.000
D48.4 Peritoneum
0.645 0.355 0.000
D48.3 Retroperitoneum
0.645 0.355 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.645 0.355 0.000
S61 Open wound of wrist and hand
0.643 0.357 0.000
F43.9 Reaction to severe stress, unspecified
0.643 0.357 0.000
F43.8 Other reactions to severe stress
0.643 0.357 0.000
S63.6 Sprain and strain of finger(s)
0.643 0.357 0.000
F23.9 Acute and transient psychotic disorder, unspecified
0.642 0.358 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.642 0.358 0.000
N99-N99 Other disorders of the genitourinary system
0.640 0.360 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.640 0.360 0.000
I07.1 Tricuspid insufficiency
0.640 0.360 0.000
R87.7 Abnormal histological findings
0.640 0.360 0.000
R27.0 Ataxia, unspecified
0.639 0.360 0.000
N60.4 Mammary duct ectasia
0.639 0.361 0.000
I73.8 Other specified peripheral vascular diseases
0.639 0.361 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.639 0.361 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.639 0.361 0.000
H74 Other disorders of middle ear and mastoid
0.639 0.361 0.000
H70 Mastoiditis and related conditions
0.639 0.361 0.000
H68 Eustachian salpingitis and obstruction
0.639 0.361 0.000
H67 Otitis media in diseases classified elsewhere
0.639 0.361 0.000
N36 Other disorders of urethra
0.638 0.362 0.000
N18.3 Chronic kidney disease, stage 3
0.638 0.362 0.000
G81 Hemiplegia
0.638 0.362 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.638 0.362 0.000
R86 Abnormal findings in specimens from male genital organs
0.638 0.362 0.000
R83 Abnormal findings in cerebrospinal fluid
0.638 0.362 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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