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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs61976746
log Bayes Factor = 16.9365
Chromosome 14   position 31,240,107  (GRCh37) Explore rs61976746 on Ensembl!
Variant rs61976746 is part of Cluster X0140

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
I73 Other peripheral vascular diseases
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.992 0.008 0.000
I50 Heart failure
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.985 0.015 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.985 0.015 0.000
I69 Sequelae of cerebrovascular disease
0.984 0.016 0.000
I65.2 Occlusion and stenosis of carotid artery
0.984 0.016 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.979 0.021 0.000
I31 Other diseases of pericardium
0.979 0.021 0.000
E65-E68 Obesity and other hyperalimentation
0.976 0.024 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.973 0.027 0.000
G90-G99 Other disorders of the nervous system
0.972 0.028 0.000
H25-H28 Disorders of lens
0.970 0.030 0.000
E66 Obesity
0.964 0.036 0.000
I73.0 Raynaud's syndrome
0.962 0.038 0.000
I31.3 Pericardial effusion (noninflammatory)
0.961 0.039 0.000
H26 Other cataract
0.960 0.040 0.000
I50.9 Heart failure, unspecified
0.959 0.041 0.000
G93 Other disorders of brain
0.958 0.042 0.000
G57 Mononeuropathies of lower limb
0.957 0.043 0.000
B35-B49 Mycoses
0.957 0.043 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.956 0.044 0.000
I73.9 Peripheral vascular disease, unspecified
0.952 0.048 0.000
S00-S09 Injuries to the head
0.950 0.050 0.000
E20-E35 Disorders of other endocrine glands
0.950 0.050 0.000
E66.9 Obesity, unspecified
0.947 0.053 0.000
H30-H36 Disorders of choroid and retina
0.944 0.056 0.000
H40-H42 Glaucoma
0.941 0.059 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.941 0.059 0.000
H33 Retinal detachments and breaks
0.939 0.061 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.936 0.064 0.000
B95-B98 Bacterial, viral and other infectious agents
0.935 0.065 0.000
G57.6 Lesion of plantar nerve
0.935 0.065 0.000
H26.4 After-cataract
0.935 0.065 0.000
I71 Aortic aneurysm and dissection
0.935 0.065 0.000
I50.1 Left ventricular failure
0.930 0.070 0.000
G81 Hemiplegia
0.929 0.071 0.000
I72 Other aneurysm
0.928 0.072 0.000
I74 Arterial embolism and thrombosis
0.927 0.073 0.000
Chapter VIII Diseases of the ear and mastoid process
0.927 0.073 0.000
I47 Paroxysmal tachycardia
0.927 0.073 0.000
M95.0 Acquired deformity of nose
0.922 0.078 0.000
B37 Candidiasis
0.920 0.080 0.000
Chapter X Diseases of the respiratory system
0.919 0.081 0.000
H33.3 Retinal breaks without detachment
0.916 0.084 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.914 0.086 0.000
G58 Other mononeuropathies
0.913 0.087 0.000
J90-J94 Other diseases of pleura
0.909 0.091 0.000
M80-M85 Disorders of bone density and structure
0.903 0.097 0.000
H40 Glaucoma
0.902 0.098 0.000
I05-I09 Chronic rheumatic heart diseases
0.901 0.099 0.000
I42 Cardiomyopathy
0.901 0.099 0.000
S00 Superficial injury of head
0.899 0.101 0.000
G81.9 Hemiplegia, unspecified
0.898 0.102 0.000
H53-H54 Visual disturbances and blindness
0.896 0.104 0.000
M45-M49 Spondylopathies
0.891 0.109 0.000
H33.0 Retinal detachment with retinal break
0.890 0.110 0.000
I63 Cerebral infarction
0.885 0.115 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.882 0.118 0.000
S02 Fracture of skull and facial bones
0.881 0.119 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.881 0.119 0.000
H26.9 Cataract, unspecified
0.881 0.119 0.000
E27 Other disorders of adrenal gland
0.881 0.119 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.877 0.123 0.000
B37.0 Candidal stomatitis
0.877 0.123 0.000
I69.3 Sequelae of cerebral infarction
0.873 0.127 0.000
I47.2 Ventricular tachycardia
0.871 0.129 0.000
G93.8 Other specified disorders of brain
0.870 0.130 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.869 0.131 0.000
I78 Diseases of capillaries
0.867 0.133 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.867 0.133 0.000
A30-A49 Other bacterial diseases
0.864 0.136 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.863 0.137 0.000
H40.0 Glaucoma suspect
0.861 0.139 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.859 0.141 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.856 0.144 0.000
S00.1 Contusion of eyelid and periocular area
0.855 0.145 0.000
J90 Pleural effusion, not elsewhere classified
0.855 0.145 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.854 0.146 0.000
S10-S19 Injuries to the neck
0.852 0.148 0.000
E10-E14 Diabetes mellitus
0.851 0.149 0.000
Chapter XXII Codes for special purposes
0.845 0.155 0.000
I77 Other disorders of arteries and arterioles
0.845 0.155 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.845 0.155 0.000
J91 Pleural effusion in conditions classified elsewhere
0.843 0.157 0.000
I51 Complications and ill-defined descriptions of heart disease
0.842 0.158 0.000
R23 Other skin changes
0.841 0.159 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.841 0.159 0.000
I08 Multiple valve diseases
0.841 0.159 0.000
J09-J18 Influenza and pneumonia
0.838 0.162 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.834 0.166 0.000
E50-E64 Other nutritional deficiencies
0.834 0.166 0.000
E66.8 Other obesity
0.833 0.167 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.831 0.169 0.000
R25 Abnormal involuntary movements
0.831 0.169 0.000
G58.9 Mononeuropathy, unspecified
0.826 0.174 0.000
I67 Other cerebrovascular diseases
0.825 0.175 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.822 0.178 0.000
S20-S29 Injuries to the thorax
0.821 0.179 0.000
Chapter XX External causes of morbidity and mortality
0.821 0.179 0.000
G93.5 Compression of brain
0.819 0.181 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.819 0.181 0.000
I72.4 Aneurysm of artery of lower extremity
0.817 0.183 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.816 0.184 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.816 0.184 0.000
E23 Hypofunction and other disorders of pituitary gland
0.815 0.185 0.000
G82 Paraplegia and tetraplegia
0.815 0.185 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.813 0.187 0.000
G93.2 Benign intracranial hypertension
0.813 0.187 0.000
G51 Facial nerve disorders
0.810 0.190 0.000
S02.2 Fracture of nasal bones
0.808 0.192 0.000
R23.8 Other and unspecified skin changes
0.808 0.192 0.000
G93.3 Postviral fatigue syndrome
0.808 0.192 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.806 0.194 0.000
H65-H75 Diseases of middle ear and mastoid
0.803 0.197 0.000
G57.5 Tarsal tunnel syndrome
0.802 0.198 0.000
M50-M54 Other dorsopathies
0.802 0.198 0.000
I42.6 Alcoholic cardiomyopathy
0.802 0.198 0.000
I61 Intracerebral haemorrhage
0.802 0.198 0.000
G40-G47 Episodic and paroxysmal disorders
0.799 0.201 0.000
H90-H95 Other disorders of ear
0.799 0.201 0.000
G95 Other diseases of spinal cord
0.797 0.203 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.795 0.205 0.000
M65-M68 Disorders of synovium and tendon
0.794 0.205 0.000
Chapter II Neoplasms
0.792 0.208 0.000
H26.8 Other specified cataract
0.790 0.210 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.790 0.210 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.790 0.210 0.000
I46 Cardiac arrest
0.790 0.210 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.790 0.210 0.000
H40.2 Primary angle-closure glaucoma
0.789 0.211 0.000
G93.0 Cerebral cysts
0.788 0.212 0.000
G70-G73 Diseases of myoneural junction and muscle
0.782 0.218 0.000
I60 Subarachnoid haemorrhage
0.782 0.218 0.000
B15-B19 Viral hepatitis
0.779 0.221 0.000
H53 Visual disturbances
0.778 0.222 0.000
M70-M79 Other soft tissue disorders
0.777 0.223 0.000
I74.5 Embolism and thrombosis of iliac artery
0.777 0.223 0.000
S01 Open wound of head
0.775 0.225 0.000
H40.5 Glaucoma secondary to other eye disorders
0.775 0.225 0.000
I10-I15 Hypertensive diseases
0.775 0.225 0.000
J94 Other pleural conditions
0.774 0.226 0.000
I31.9 Disease of pericardium, unspecified
0.773 0.227 0.000
G58.8 Other specified mononeuropathies
0.772 0.228 0.000
E27.8 Other specified disorders of adrenal gland
0.771 0.229 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.769 0.231 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.768 0.232 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.767 0.233 0.000
S50-S59 Injuries to the elbow and forearm
0.766 0.233 0.000
B44 Aspergillosis
0.766 0.234 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.765 0.235 0.000
H27 Other disorders of lens
0.765 0.235 0.000
M45 Ankylosing spondylitis
0.764 0.236 0.000
I72.9 Aneurysm of unspecified site
0.762 0.238 0.000
J30-J39 Other diseases of upper respiratory tract
0.761 0.239 0.000
E28 Ovarian dysfunction
0.761 0.239 0.000
R25.1 Tremor, unspecified
0.760 0.240 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.760 0.240 0.000
I78.1 Naevus, nonneoplastic
0.760 0.240 0.000
I51.7 Cardiomegaly
0.758 0.242 0.000
B37.2 Candidiasis of skin and nail
0.758 0.242 0.000
S60-S69 Injuries to the wrist and hand
0.758 0.242 0.000
G93.6 Cerebral oedema
0.757 0.243 0.000
S02.20 Fracture of nasal bones (closed)
0.756 0.244 0.000
H80-H83 Diseases of inner ear
0.755 0.245 0.000
E10 Insulin-dependent diabetes mellitus
0.752 0.248 0.000
G61 Inflammatory polyneuropathy
0.751 0.249 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.750 0.250 0.000
S00.0 Superficial injury of scalp
0.750 0.250 0.000
G43 Migraine
0.749 0.251 0.000
I63.9 Cerebral infarction, unspecified
0.748 0.252 0.000
H33.5 Other retinal detachments
0.747 0.253 0.000
G54 Nerve root and plexus disorders
0.747 0.253 0.000
A49 Bacterial infection of unspecified site
0.746 0.254 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.745 0.255 0.000
I08.0 Disorders of both mitral and aortic valves
0.744 0.256 0.000
I80 Phlebitis and thrombophlebitis
0.744 0.256 0.000
H54 Blindness and low vision
0.742 0.258 0.000
A80-A89 Viral infections of the central nervous system
0.742 0.258 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.742 0.258 0.000
M60-M63 Disorders of muscles
0.741 0.259 0.000
R25.2 Cramp and spasm
0.739 0.261 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.738 0.262 0.000
H33.1 Retinoschisis and retinal cysts
0.738 0.262 0.000
M81 Osteoporosis without pathological fracture
0.738 0.262 0.000
G83 Other paralytic syndromes
0.736 0.264 0.000
E34 Other endocrine disorders
0.736 0.264 0.000
E16 Other disorders of pancreatic internal secretion
0.736 0.264 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.735 0.265 0.000
M54 Dorsalgia
0.735 0.265 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.734 0.266 0.000
B37.1 Pulmonary candidiasis
0.731 0.269 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.730 0.270 0.000
M47 Spondylosis
0.730 0.270 0.000
M79.6 Pain in limb
0.728 0.272 0.000
J32 Chronic sinusitis
0.728 0.272 0.000
M86-M90 Other osteopathies
0.727 0.273 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.726 0.274 0.000
G80 Infantile cerebral palsy
0.725 0.275 0.000
S90-S99 Injuries to the ankle and foot
0.725 0.275 0.000
M80 Osteoporosis with pathological fracture
0.724 0.276 0.000
J18 Pneumonia, organism unspecified
0.723 0.277 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.723 0.277 0.000
R27 Other lack of coordination
0.723 0.277 0.000
I72.8 Aneurysm of other specified arteries
0.721 0.279 0.000
M85 Other disorders of bone density and structure
0.720 0.280 0.000
I05 Rheumatic mitral valve diseases
0.720 0.280 0.000
E23.0 Hypopituitarism
0.719 0.281 0.000
E14 Unspecified diabetes mellitus
0.719 0.281 0.000
J32.9 Chronic sinusitis, unspecified
0.719 0.281 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.718 0.282 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.717 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.717 0.283 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.717 0.283 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.717 0.283 0.000
S01.3 Open wound of ear
0.716 0.284 0.000
E29 Testicular dysfunction
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
S02.4 Fracture of malar and maxillary bones
0.716 0.284 0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.715 0.285 0.000
H33.4 Traction detachment of retina
0.715 0.285 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.715 0.285 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.714 0.286 0.000
R20 Disturbances of skin sensation
0.713 0.287 0.000
I73.8 Other specified peripheral vascular diseases
0.712 0.288 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.712 0.288 0.000
R47-R49 Symptoms and signs involving speech and voice
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.711 0.289 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.711 0.289 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.711 0.289 0.000
I65.1 Occlusion and stenosis of basilar artery
0.711 0.289 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.711 0.289 0.000
G91 Hydrocephalus
0.710 0.290 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.710 0.290 0.000
H53.9 Visual disturbance, unspecified
0.710 0.290 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.709 0.291 0.000
B37.4 Candidiasis of other urogenital sites
0.708 0.292 0.000
I42.2 Other hypertrophic cardiomyopathy
0.707 0.293 0.000
E27.1 Primary adrenocortical insufficiency
0.707 0.293 0.000
T33-T35 Frostbite
0.706 0.293 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.706 0.293 0.000
T00-T07 Injuries involving multiple body regions
0.706 0.293 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.706 0.294 0.000
M84 Disorders of continuity of bone
0.706 0.294 0.000
D10-D36 Benign neoplasms
0.704 0.296 0.000
S02.0 Fracture of vault of skull
0.703 0.297 0.000
E20 Hypoparathyroidism
0.703 0.297 0.000
I67.9 Cerebrovascular disease, unspecified
0.702 0.298 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.702 0.298 0.000
G52 Disorders of other cranial nerves
0.702 0.298 0.000
I31.8 Other specified diseases of pericardium
0.702 0.298 0.000
I31.2 Haemopericardium, not elsewhere classified
0.702 0.298 0.000
I31.1 Chronic constrictive pericarditis
0.702 0.298 0.000
I31.0 Chronic adhesive pericarditis
0.702 0.298 0.000
H53.2 Diplopia
0.701 0.299 0.000
S70-S79 Injuries to the hip and thigh
0.701 0.299 0.000
E67 Other hyperalimentation
0.700 0.300 0.000
E68 Sequelae of hyperalimentation
0.700 0.300 0.000
G82.2 Paraplegia, unspecified
0.700 0.300 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.700 0.300 0.000
T87 Complications peculiar to reattachment and amputation
0.699 0.301 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.697 0.302 0.000
M79.62 Pain in limb (Upper arm)
0.697 0.303 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.697 0.303 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.697 0.303 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.697 0.303 0.000
G92 Toxic encephalopathy
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.696 0.304 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.696 0.304 0.000
E53 Deficiency of other B group vitamins
0.695 0.305 0.000
I10 Essential (primary) hypertension
0.695 0.305 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.695 0.305 0.000
S01.9 Open wound of head, part unspecified
0.694 0.306 0.000
G93.9 Disorder of brain, unspecified
0.694 0.306 0.000
I46.9 Cardiac arrest, unspecified
0.694 0.306 0.000
B49 Unspecified mycosis
0.693 0.307 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.693 0.307 0.000
S14 Injury of nerves and spinal cord at neck level
0.693 0.307 0.000
G43.1 Migraine with aura [classical migraine]
0.693 0.307 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.692 0.308 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.691 0.308 0.000
E66.1 Drug-induced obesity
0.691 0.308 0.000
E66.0 Obesity due to excess calories
0.691 0.308 0.000
T91 Sequelae of injuries of neck and trunk
0.691 0.308 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.689 0.311 0.000
H26.3 Drug-induced cataract
0.688 0.311 0.000
S00.8 Superficial injury of other parts of head
0.688 0.312 0.000
R23.0 Cyanosis
0.688 0.312 0.000
G51.0 Bell's palsy
0.688 0.312 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.687 0.313 0.000
G93.7 Reye's syndrome
0.687 0.313 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.686 0.313 0.000
G57.4 Lesion of medial popliteal nerve
0.686 0.313 0.000
G57.3 Lesion of lateral popliteal nerve
0.686 0.313 0.000
G57.2 Lesion of femoral nerve
0.686 0.313 0.000
G57.1 Meralgia paraesthetica
0.686 0.313 0.000
G57.0 Lesion of sciatic nerve
0.686 0.313 0.000
B48 Other mycoses, not elsewhere classified
0.686 0.314 0.000
B47 Mycetoma
0.686 0.314 0.000
B46 Zygomycosis
0.686 0.314 0.000
B45 Cryptococcosis
0.686 0.314 0.000
B43 Chromomycosis and phaeomycotic abscess
0.686 0.314 0.000
B42 Sporotrichosis
0.686 0.314 0.000
B41 Paracoccidioidomycosis
0.686 0.314 0.000
B40 Blastomycosis
0.686 0.314 0.000
B39 Histoplasmosis
0.686 0.314 0.000
B38 Coccidioidomycosis
0.686 0.314 0.000
B36 Other superficial mycoses
0.686 0.314 0.000
B35 Dermatophytosis
0.686 0.314 0.000
M99 Biomechanical lesions, not elsewhere classified
0.685 0.315 0.000
H43-H45 Disorders of vitreous body and globe
0.685 0.315 0.000
R21 Rash and other nonspecific skin eruption
0.685 0.315 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.684 0.316 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.683 0.317 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.683 0.317 0.000
C45 Mesothelioma
0.683 0.317 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.682 0.317 0.000
H10-H13 Disorders of conjunctiva
0.682 0.318 0.000
S40-S49 Injuries to the shoulder and upper arm
0.682 0.318 0.000
J60-J70 Lung diseases due to external agents
0.682 0.318 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.682 0.318 0.000
I37 Pulmonary valve disorders
0.681 0.318 0.000
S08 Traumatic amputation of part of head
0.681 0.319 0.000
S07 Crushing injury of head
0.681 0.319 0.000
S05 Injury of eye and orbit
0.681 0.319 0.000
S04 Injury of cranial nerves
0.681 0.319 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.681 0.319 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.681 0.319 0.000
E32 Diseases of thymus
0.681 0.319 0.000
E31 Polyglandular dysfunction
0.681 0.319 0.000
E30 Disorders of puberty, not elsewhere classified
0.681 0.319 0.000
E25 Adrenogenital disorders
0.681 0.319 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.681 0.319 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.681 0.319 0.000
M91-M94 Chondropathies
0.681 0.319 0.000
M46 Other inflammatory spondylopathies
0.681 0.319 0.000
J18.9 Pneumonia, unspecified
0.680 0.320 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.680 0.320 0.000
R22.0 Localised swelling, mass and lump, head
0.680 0.320 0.000
I72.3 Aneurysm of iliac artery
0.680 0.320 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.679 0.321 0.000
S02.1 Fracture of base of skull
0.678 0.321 0.000
D36 Benign neoplasm of other and unspecified sites
0.678 0.322 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.677 0.323 0.000
H30 Chorioretinal inflammation
0.677 0.323 0.000
I71.0 Dissection of aorta [any part]
0.676 0.324 0.000
H71 Cholesteatoma of middle ear
0.676 0.324 0.000
M79.60 Pain in limb (Multiple sites)
0.676 0.324 0.000
D45 Polycythaemia vera
0.676 0.324 0.000
S10 Superficial injury of neck
0.675 0.325 0.000
H42 Glaucoma in diseases classified elsewhere
0.675 0.325 0.000
G12 Spinal muscular atrophy and related syndromes
0.675 0.325 0.000
E26 Hyperaldosteronism
0.674 0.326 0.000
B99-B99 Other infectious diseases
0.673 0.327 0.000
T90 Sequelae of injuries of head
0.672 0.328 0.000
M82 Osteoporosis in diseases classified elsewhere
0.672 0.328 0.000
J92 Pleural plaque
0.672 0.328 0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.671 0.329 0.000
M95.8 Other specified acquired deformities of musculoskeletal system
0.671 0.329 0.000
M95.5 Acquired deformity of pelvis
0.671 0.329 0.000
M95.4 Acquired deformity of chest and rib
0.671 0.329 0.000
M95.3 Acquired deformity of neck
0.671 0.329 0.000
M95.2 Other acquired deformity of head
0.671 0.329 0.000
M95.1 Cauliflower ear
0.671 0.329 0.000
E40-E46 Malnutrition
0.671 0.329 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.671 0.329 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.671 0.329 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.671 0.329 0.000
S01.8 Open wound of other parts of head
0.670 0.330 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.670 0.330 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.670 0.330 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.670 0.330 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.670 0.330 0.000
H90 Conductive and sensorineural hearing loss
0.670 0.330 0.000
B25-B34 Other viral diseases
0.669 0.331 0.000
E24 Cushing's syndrome
0.668 0.332 0.000
H26.0 Infantile, juvenile and presenile cataract
0.668 0.332 0.000
S00.9 Superficial injury of head, part unspecified
0.667 0.333 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.667 0.333 0.000
G81.1 Spastic hemiplegia
0.666 0.334 0.000
G81.0 Flaccid hemiplegia
0.666 0.334 0.000
I08.8 Other multiple valve diseases
0.666 0.334 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.665 0.335 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.665 0.335 0.000
I72.2 Aneurysm of renal artery
0.665 0.335 0.000
I72.1 Aneurysm of artery of upper extremity
0.665 0.335 0.000
I72.0 Aneurysm of carotid artery
0.665 0.335 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.665 0.335 0.000
I74.8 Embolism and thrombosis of other arteries
0.665 0.335 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.665 0.335 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.665 0.335 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.665 0.335 0.000
B37.8 Candidiasis of other sites
0.665 0.335 0.000
M47.8 Other spondylosis
0.665 0.335 0.000
I47.0 Reentry ventricular arrhythmia
0.664 0.335 0.000
H73 Other disorders of tympanic membrane
0.663 0.337 0.000
G20-G26 Extrapyramidal and movement disorders
0.663 0.337 0.000
H31 Other disorders of choroid
0.663 0.337 0.000
M65 Synovitis and tenosynovitis
0.662 0.338 0.000
A41 Other septicaemia
0.662 0.338 0.000
I36 Nonrheumatic tricuspid valve disorders
0.661 0.338 0.000
T66-T78 Other and unspecified effects of external causes
0.661 0.339 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.661 0.339 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.661 0.339 0.000
I45 Other conduction disorders
0.660 0.340 0.000
C51-C58 Malignant neoplasms of female genital organs
0.660 0.340 0.000
B37.7 Candidal septicaemia
0.659 0.341 0.000
B37.6 Candidal endocarditis
0.659 0.341 0.000
B37.5 Candidal meningitis
0.659 0.341 0.000
E16.2 Hypoglycaemia, unspecified
0.658 0.342 0.000
S02.8 Fractures of other skull and facial bones
0.658 0.342 0.000
G11 Hereditary ataxia
0.658 0.342 0.000
M54.4 Lumbago with sciatica
0.658 0.342 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.657 0.342 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.657 0.343 0.000
J10 Influenza due to identified influenza virus
0.657 0.343 0.000
G90 Disorders of autonomic nervous system
0.656 0.344 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.656 0.344 0.000
E61 Deficiency of other nutrient elements
0.656 0.344 0.000
I77.0 Arteriovenous fistula, acquired
0.656 0.344 0.000
T79-T79 Certain early complications of trauma
0.655 0.345 0.000
G58.7 Mononeuritis multiplex
0.655 0.345 0.000
G58.0 Intercostal neuropathy
0.655 0.345 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.654 0.346 0.000
H83 Other diseases of inner ear
0.654 0.346 0.000
H92 Otalgia and effusion of ear
0.654 0.346 0.000
I70 Atherosclerosis
0.652 0.348 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.651 0.349 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.651 0.349 0.000
R23.3 Spontaneous ecchymoses
0.650 0.350 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.650 0.350 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.649 0.351 0.000
G95.9 Disease of spinal cord, unspecified
0.649 0.351 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.649 0.351 0.000
D25 Leiomyoma of uterus
0.648 0.352 0.000
M83 Adult osteomalacia
0.648 0.352 0.000
Q80-Q89 Other congenital malformations
0.648 0.352 0.000
H26.2 Complicated cataract
0.647 0.352 0.000
I62 Other nontraumatic intracranial haemorrhage
0.647 0.353 0.000
M40-M43 Deforming dorsopathies
0.647 0.353 0.000
H40.6 Glaucoma secondary to drugs
0.647 0.353 0.000
H40.4 Glaucoma secondary to eye inflammation
0.647 0.353 0.000
H40.3 Glaucoma secondary to eye trauma
0.647 0.353 0.000
I09 Other rheumatic heart diseases
0.646 0.354 0.000
I06 Rheumatic aortic valve diseases
0.646 0.354 0.000
G95.0 Syringomyelia and syringobulbia
0.646 0.354 0.000
G43.8 Other migraine
0.646 0.354 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.646 0.354 0.000
I42.5 Other restrictive cardiomyopathy
0.646 0.354 0.000
I42.4 Endocardial fibroelastosis
0.646 0.354 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.646 0.354 0.000
I30 Acute pericarditis
0.645 0.355 0.000
E65 Localised adiposity
0.645 0.355 0.000
S00.5 Superficial injury of lip and oral cavity
0.644 0.355 0.000
S00.4 Superficial injury of ear
0.644 0.355 0.000
G71 Primary disorders of muscles
0.644 0.356 0.000
M79.64 Pain in limb (Hand)
0.644 0.356 0.000
E10.4 With neurological complications
0.643 0.357 0.000
H72 Perforation of tympanic membrane
0.643 0.357 0.000
M48 Other spondylopathies
0.643 0.357 0.000
S30.1 Contusion of abdominal wall
0.643 0.357 0.000
I50.0 Congestive heart failure
0.643 0.357 0.000
E22 Hyperfunction of pituitary gland
0.640 0.359 0.000
Q00-Q07 Congenital malformations of the nervous system
0.640 0.360 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.640 0.360 0.000
S52 Fracture of forearm
0.640 0.360 0.000
H91 Other hearing loss
0.640 0.360 0.000
V40-V49 Car occupant injured in transport accident
0.639 0.361 0.000
M49 Spondylopathies in diseases classified elsewhere
0.639 0.361 0.000
S27 Injury of other and unspecified intrathoracic organs
0.638 0.362 0.000
I42.0 Dilated cardiomyopathy
0.638 0.362 0.000
H40.1 Primary open-angle glaucoma
0.637 0.363 0.000
J34 Other disorders of nose and nasal sinuses
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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