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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6420398
log Bayes Factor = 18.8598
Chromosome 16   position 76,991,593  (GRCh37) Explore rs6420398 on Ensembl!
Variant rs6420398 is part of Cluster X0073

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
D10-D36 Benign neoplasms
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.992 0.008 0.000
N17-N19 Renal failure
0.991 0.009 0.000
B95-B98 Bacterial, viral and other infectious agents
0.986 0.014 0.000
M70-M79 Other soft tissue disorders
0.985 0.015 0.000
C60-C63 Malignant neoplasms of male genital organs
0.979 0.021 0.000
Chapter VII Diseases of the eye and adnexa
0.978 0.022 0.000
F10.2 Dependence syndrome
0.977 0.023 0.000
F30-F39 Mood [affective] disorders
0.975 0.025 0.000
T81 Complications of procedures, not elsewhere classified
0.971 0.029 0.000
C61 Malignant neoplasm of prostate
0.966 0.034 0.000
M05-M14 Inflammatory polyarthropathies
0.956 0.044 0.000
N19 Unspecified renal failure
0.951 0.049 0.000
F32 Depressive episode
0.949 0.051 0.000
N18 Chronic renal failure
0.948 0.052 0.000
F10.3 Withdrawal state
0.947 0.053 0.000
I30-I52 Other forms of heart disease
0.942 0.058 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.941 0.059 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.941 0.059 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.938 0.062 0.000
S80-S89 Injuries to the knee and lower leg
0.936 0.064 0.000
N25-N29 Other disorders of kidney and ureter
0.936 0.064 0.000
I60-I69 Cerebrovascular diseases
0.936 0.064 0.000
Chapter XXI Factors influencing health status and contact with health services
0.934 0.066 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.928 0.072 0.000
F32.9 Depressive episode, unspecified
0.927 0.073 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.922 0.078 0.000
D22 Melanocytic naevi
0.921 0.079 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.921 0.079 0.000
F10.1 Harmful use
0.921 0.079 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.913 0.087 0.000
Chapter X Diseases of the respiratory system
0.908 0.092 0.000
D23 Other benign neoplasms of skin
0.907 0.093 0.000
D27 Benign neoplasm of ovary
0.906 0.094 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.906 0.094 0.000
M80-M85 Disorders of bone density and structure
0.904 0.096 0.000
I20-I25 Ischaemic heart diseases
0.902 0.098 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.896 0.104 0.000
D24 Benign neoplasm of breast
0.895 0.105 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.893 0.107 0.000
Chapter XX External causes of morbidity and mortality
0.884 0.116 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.882 0.118 0.000
Z60 Problems related to social environment
0.881 0.119 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.879 0.121 0.000
H30-H36 Disorders of choroid and retina
0.877 0.123 0.000
I25 Chronic ischaemic heart disease
0.875 0.125 0.000
C64-C68 Malignant neoplasms of urinary tract
0.870 0.130 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.867 0.133 0.000
M79.6 Pain in limb
0.867 0.133 0.000
I67 Other cerebrovascular diseases
0.864 0.136 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.858 0.142 0.000
S82 Fracture of lower leg, including ankle
0.858 0.142 0.000
Z60.2 Living alone
0.858 0.142 0.000
I05-I09 Chronic rheumatic heart diseases
0.854 0.146 0.000
I35 Nonrheumatic aortic valve disorders
0.852 0.148 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.852 0.148 0.000
I25.2 Old myocardial infarction
0.852 0.148 0.000
F17.1 Harmful use
0.850 0.150 0.000
A30-A49 Other bacterial diseases
0.849 0.151 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.848 0.152 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.847 0.153 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.847 0.153 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.846 0.154 0.000
H25-H28 Disorders of lens
0.844 0.156 0.000
N17 Acute renal failure
0.844 0.156 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.844 0.156 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.842 0.158 0.000
F10.0 Acute intoxication
0.841 0.159 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.839 0.161 0.000
I34 Nonrheumatic mitral valve disorders
0.839 0.161 0.000
J30-J39 Other diseases of upper respiratory tract
0.838 0.162 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.837 0.162 0.000
S81 Open wound of lower leg
0.833 0.167 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.831 0.169 0.000
M50-M54 Other dorsopathies
0.831 0.169 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.831 0.169 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.830 0.170 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.828 0.172 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.827 0.172 0.000
H33 Retinal detachments and breaks
0.827 0.173 0.000
M72 Fibroblastic disorders
0.826 0.173 0.000
M11 Other crystal arthropathies
0.825 0.175 0.000
N18.3 Chronic kidney disease, stage 3
0.824 0.176 0.000
J33 Nasal polyp
0.823 0.177 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.822 0.178 0.000
T43.2 Other and unspecified antidepressants
0.822 0.178 0.000
D60-D64 Aplastic and other anaemias
0.822 0.178 0.000
S20-S29 Injuries to the thorax
0.821 0.179 0.000
N00-N08 Glomerular diseases
0.820 0.180 0.000
S90-S99 Injuries to the ankle and foot
0.818 0.182 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.818 0.182 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.817 0.183 0.000
I50 Heart failure
0.817 0.183 0.000
T39.1 4-Aminophenol derivatives
0.816 0.184 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.816 0.184 0.000
Chapter XXII Codes for special purposes
0.815 0.185 0.000
M86-M90 Other osteopathies
0.809 0.191 0.000
S10-S19 Injuries to the neck
0.809 0.191 0.000
M80 Osteoporosis with pathological fracture
0.809 0.191 0.000
D23.1 Skin of eyelid, including canthus
0.808 0.192 0.000
N10-N16 Renal tubulo-interstitial diseases
0.808 0.192 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.808 0.192 0.000
H55-H59 Other disorders of eye and adnexa
0.808 0.192 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.808 0.192 0.000
B15-B19 Viral hepatitis
0.808 0.192 0.000
W00-W19 Falls
0.804 0.196 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.803 0.197 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.802 0.198 0.000
F33 Recurrent depressive disorder
0.800 0.200 0.000
C51-C58 Malignant neoplasms of female genital organs
0.800 0.200 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.796 0.204 0.000
M79.1 Myalgia
0.796 0.204 0.000
D30 Benign neoplasm of urinary organs
0.795 0.205 0.000
D36 Benign neoplasm of other and unspecified sites
0.793 0.207 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.793 0.207 0.000
N18.9 Chronic renal failure, unspecified
0.793 0.207 0.000
M07 Psoriatic and enteropathic arthropathies
0.791 0.209 0.000
S00-S09 Injuries to the head
0.791 0.209 0.000
J00-J06 Acute upper respiratory infections
0.790 0.210 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.788 0.212 0.000
M75 Shoulder lesions
0.787 0.213 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.785 0.215 0.000
M77 Other enthesopathies
0.784 0.216 0.000
N18.4 Chronic kidney disease, stage 4
0.783 0.217 0.000
I63 Cerebral infarction
0.783 0.217 0.000
D62 Acute posthaemorrhagic anaemia
0.781 0.219 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.779 0.221 0.000
I62 Other nontraumatic intracranial haemorrhage
0.778 0.222 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.778 0.222 0.000
S82.1 Fracture of upper end of tibia
0.777 0.223 0.000
C15-C26 Malignant neoplasms of digestive organs
0.774 0.226 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.774 0.226 0.000
J33.8 Other polyp of sinus
0.773 0.227 0.000
N20-N23 Urolithiasis
0.771 0.229 0.000
B02 Zoster [herpes zoster]
0.771 0.229 0.000
T39.0 Salicylates
0.769 0.231 0.000
H25 Senile cataract
0.767 0.233 0.000
I67.9 Cerebrovascular disease, unspecified
0.765 0.235 0.000
M06 Other rheumatoid arthritis
0.765 0.235 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.764 0.235 0.000
N18.5 Chronic kidney disease, stage 5
0.764 0.236 0.000
M20-M25 Other joint disorders
0.764 0.236 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.762 0.238 0.000
M79.62 Pain in limb (Upper arm)
0.762 0.238 0.000
M13 Other arthritis
0.760 0.240 0.000
H53-H54 Visual disturbances and blindness
0.759 0.241 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.759 0.241 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.758 0.242 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.758 0.242 0.000
C45 Mesothelioma
0.757 0.243 0.000
I35.0 Aortic (valve) stenosis
0.753 0.247 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.753 0.247 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.753 0.247 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.751 0.249 0.000
Z57 Occupational exposure to risk-factors
0.750 0.250 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.750 0.250 0.000
I36 Nonrheumatic tricuspid valve disorders
0.750 0.250 0.000
I45 Other conduction disorders
0.750 0.250 0.000
H10-H13 Disorders of conjunctiva
0.748 0.252 0.000
I34.0 Mitral (valve) insufficiency
0.746 0.254 0.000
Z45 Adjustment and management of implanted device
0.744 0.256 0.000
W19 Unspecified fall
0.744 0.256 0.000
M05 Seropositive rheumatoid arthritis
0.743 0.257 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.742 0.258 0.000
J90-J94 Other diseases of pleura
0.742 0.258 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.741 0.259 0.000
D23.4 Skin of scalp and neck
0.740 0.260 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.740 0.260 0.000
N17.9 Acute renal failure, unspecified
0.739 0.261 0.000
H18 Other disorders of cornea
0.739 0.261 0.000
H33.0 Retinal detachment with retinal break
0.739 0.261 0.000
M75.1 Rotator cuff syndrome
0.738 0.262 0.000
Z50 Care involving use of rehabilitation procedures
0.738 0.262 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.735 0.265 0.000
I69 Sequelae of cerebrovascular disease
0.735 0.265 0.000
A41 Other septicaemia
0.734 0.266 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.732 0.268 0.000
M11.2 Other chondrocalcinosis
0.731 0.269 0.000
F99-F99 Unspecified mental disorder
0.731 0.269 0.000
I35.1 Aortic (valve) insufficiency
0.729 0.271 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.729 0.271 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.728 0.272 0.000
I50.0 Congestive heart failure
0.728 0.272 0.000
J33.9 Nasal polyp, unspecified
0.728 0.272 0.000
M79.63 Pain in limb (Forearm)
0.726 0.274 0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.724 0.276 0.000
Z75 Problems related to medical facilities and other health care
0.724 0.276 0.000
D23.9 Skin, unspecified
0.724 0.276 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.722 0.277 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.721 0.279 0.000
D34 Benign neoplasm of thyroid gland
0.721 0.279 0.000
S82.4 Fracture of fibula alone
0.721 0.279 0.000
D18 Haemangioma and lymphangioma, any site
0.719 0.280 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.719 0.281 0.000
S82.10 Fracture of upper end of tibia (closed)
0.719 0.281 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.718 0.282 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F80-F89 Disorders of psychological development
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.717 0.283 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.717 0.283 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.717 0.283 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.717 0.283 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.717 0.283 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.717 0.283 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.717 0.283 0.000
F11 Mental and behavioural disorders due to use of opioids
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Z63 Other problems related to primary support group, including family circumstances
0.716 0.284 0.000
M79.0 Rheumatism, unspecified
0.716 0.284 0.000
F10.9 Unspecified mental and behavioural disorder
0.716 0.284 0.000
F10.8 Other mental and behavioural disorders
0.716 0.284 0.000
F10.7 Residual and late-onset psychotic disorder
0.716 0.284 0.000
F10.6 Amnesic syndrome
0.716 0.284 0.000
F10.5 Psychotic disorder
0.716 0.284 0.000
F10.4 Withdrawal state with delirium
0.716 0.284 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.716 0.284 0.000
M79.7 Fibromyalgia
0.715 0.285 0.000
B99-B99 Other infectious diseases
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.715 0.285 0.000
B65-B83 Helminthiases
0.715 0.285 0.000
B50-B64 Protozoal diseases
0.715 0.285 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.715 0.285 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.715 0.285 0.000
A80-A89 Viral infections of the central nervous system
0.715 0.285 0.000
A75-A79 Rickettsioses
0.715 0.285 0.000
A70-A74 Other diseases caused by chlamydiae
0.715 0.285 0.000
A65-A69 Other spirochaetal diseases
0.715 0.285 0.000
A20-A28 Certain zoonotic bacterial diseases
0.715 0.285 0.000
A15-A19 Tuberculosis
0.715 0.285 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.715 0.285 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.715 0.285 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.714 0.286 0.000
H25.0 Senile incipient cataract
0.714 0.286 0.000
D31 Benign neoplasm of eye and adnexa
0.714 0.286 0.000
D29 Benign neoplasm of male genital organs
0.714 0.286 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.714 0.286 0.000
D26 Other benign neoplasms of uterus
0.714 0.286 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.714 0.286 0.000
D19 Benign neoplasm of mesothelial tissue
0.714 0.286 0.000
D16 Benign neoplasm of bone and articular cartilage
0.714 0.286 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.714 0.286 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.714 0.286 0.000
D11 Benign neoplasm of major salivary glands
0.714 0.286 0.000
C65 Malignant neoplasm of renal pelvis
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.713 0.287 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.713 0.287 0.000
S60-S69 Injuries to the wrist and hand
0.712 0.288 0.000
M25 Other joint disorders, not elsewhere classified
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.288 0.000
T86 Failure and rejection of transplanted organs and tissues
0.712 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
Z41 Procedures for purposes other than remedying health state
0.712 0.288 0.000
D68 Other coagulation defects
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.711 0.289 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.711 0.289 0.000
C73 Malignant neoplasm of thyroid gland
0.710 0.290 0.000
I38 Endocarditis, valve unspecified
0.710 0.290 0.000
M79.69 Pain in limb (Site unspecified)
0.709 0.291 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.709 0.291 0.000
D00-D09 In situ neoplasms
0.708 0.292 0.000
N99-N99 Other disorders of the genitourinary system
0.708 0.292 0.000
S89 Other and unspecified injuries of lower leg
0.708 0.292 0.000
T51 Toxic effect of alcohol
0.708 0.292 0.000
D10 Benign neoplasm of mouth and pharynx
0.708 0.292 0.000
I22 Subsequent myocardial infarction
0.707 0.293 0.000
H17 Corneal scars and opacities
0.707 0.293 0.000
M76 Enthesopathies of lower limb, excluding foot
0.706 0.294 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.706 0.294 0.000
M71 Other bursopathies
0.706 0.294 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.706 0.294 0.000
D50-D53 Nutritional anaemias
0.706 0.294 0.000
H34 Retinal vascular occlusions
0.704 0.296 0.000
M81 Osteoporosis without pathological fracture
0.704 0.296 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.704 0.296 0.000
N28.8 Other specified disorders of kidney and ureter
0.703 0.297 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.703 0.297 0.000
J33.0 Polyp of nasal cavity
0.702 0.298 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.702 0.298 0.000
C60 Malignant neoplasm of penis
0.702 0.298 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.701 0.299 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.701 0.299 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.700 0.300 0.000
I61 Intracerebral haemorrhage
0.699 0.301 0.000
F38 Other mood [affective] disorders
0.699 0.301 0.000
F34 Persistent mood [affective] disorders
0.699 0.301 0.000
F30 Manic episode
0.699 0.301 0.000
F39 Unspecified mood [affective] disorder
0.699 0.301 0.000
H33.3 Retinal breaks without detachment
0.698 0.301 0.000
H33.5 Other retinal detachments
0.698 0.302 0.000
M54 Dorsalgia
0.698 0.302 0.000
B07 Viral warts
0.697 0.303 0.000
T81.9 Unspecified complication of procedure
0.696 0.303 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.696 0.303 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.696 0.303 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.696 0.303 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.696 0.303 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.696 0.303 0.000
Z73 Problems related to life-management difficulty
0.694 0.306 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.693 0.307 0.000
M45-M49 Spondylopathies
0.693 0.307 0.000
B35-B49 Mycoses
0.692 0.308 0.000
H43-H45 Disorders of vitreous body and globe
0.691 0.309 0.000
B02.9 Zoster without complication
0.691 0.309 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.690 0.309 0.000
S70-S79 Injuries to the hip and thigh
0.690 0.310 0.000
M10 Gout
0.689 0.311 0.000
D23.3 Skin of other and unspecified parts of face
0.689 0.311 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.689 0.311 0.000
F20 Schizophrenia
0.688 0.312 0.000
Z49 Care involving dialysis
0.687 0.313 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.687 0.313 0.000
W20-W49 Exposure to inanimate mechanical forces
0.686 0.314 0.000
M14 Arthropathies in other diseases classified elsewhere
0.685 0.315 0.000
M12 Other specific arthropathies
0.685 0.315 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.685 0.315 0.000
M08 Juvenile arthritis
0.685 0.315 0.000
A00-A09 Intestinal infectious diseases
0.685 0.315 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.685 0.315 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.684 0.315 0.000
I47 Paroxysmal tachycardia
0.684 0.316 0.000
J92 Pleural plaque
0.684 0.316 0.000
I05 Rheumatic mitral valve diseases
0.684 0.316 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.684 0.316 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.683 0.317 0.000
I44 Atrioventricular and left bundle-branch block
0.682 0.318 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.682 0.318 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.681 0.319 0.000
I07 Rheumatic tricuspid valve diseases
0.681 0.319 0.000
Z50.1 Other physical therapy
0.681 0.319 0.000
F32.8 Other depressive episodes
0.680 0.319 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.680 0.319 0.000
F32.1 Moderate depressive episode
0.680 0.319 0.000
F32.0 Mild depressive episode
0.680 0.319 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.680 0.320 0.000
S50-S59 Injuries to the elbow and forearm
0.680 0.320 0.000
N18.8 Other chronic renal failure
0.679 0.320 0.000
N18.2 Chronic kidney disease, stage 2
0.679 0.320 0.000
N18.1 Chronic kidney disease, stage 1
0.679 0.320 0.000
S81.9 Open wound of lower leg, part unspecified
0.679 0.321 0.000
D35.1 Parathyroid gland
0.679 0.321 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.679 0.321 0.000
F31 Bipolar affective disorder
0.675 0.325 0.000
I52 Other heart disorders in diseases classified elsewhere
0.675 0.325 0.000
I48 Atrial fibrillation and flutter
0.675 0.325 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.675 0.325 0.000
I41 Myocarditis in diseases classified elsewhere
0.675 0.325 0.000
I40 Acute myocarditis
0.675 0.325 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.675 0.325 0.000
I37 Pulmonary valve disorders
0.675 0.325 0.000
I33 Acute and subacute endocarditis
0.675 0.325 0.000
I32 Pericarditis in diseases classified elsewhere
0.675 0.325 0.000
I30 Acute pericarditis
0.675 0.325 0.000
M79.9 Soft tissue disorder, unspecified
0.675 0.325 0.000
M79.5 Residual foreign body in soft tissue
0.675 0.325 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.675 0.325 0.000
M79.3 Panniculitis, unspecified
0.675 0.325 0.000
M79.2 Neuralgia and neuritis, unspecified
0.675 0.325 0.000
Z40 Prophylactic surgery
0.675 0.325 0.000
I67.8 Other specified cerebrovascular diseases
0.675 0.325 0.000
D22.0 Melanocytic naevi of lip
0.674 0.326 0.000
S81.8 Open wound of other parts of lower leg
0.673 0.327 0.000
M07.3 Other psoriatic arthropathies
0.673 0.327 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.673 0.327 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.673 0.327 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.673 0.327 0.000
J06.9 Acute upper respiratory infection, unspecified
0.672 0.328 0.000
B18 Chronic viral hepatitis
0.672 0.328 0.000
S88 Traumatic amputation of lower leg
0.671 0.329 0.000
S87 Crushing injury of lower leg
0.671 0.329 0.000
S86 Injury of muscle and tendon at lower leg level
0.671 0.329 0.000
S85 Injury of blood vessels at lower leg level
0.671 0.329 0.000
S84 Injury of nerves at lower leg level
0.671 0.329 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.671 0.329 0.000
N27 Small kidney of unknown cause
0.671 0.329 0.000
N25 Disorders resulting from impaired renal tubular function
0.671 0.329 0.000
N26 Unspecified contracted kidney
0.671 0.329 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.671 0.329 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.671 0.329 0.000
W19.9 Unspecified place
0.671 0.329 0.000
M84 Disorders of continuity of bone
0.670 0.330 0.000
S82.5 Fracture of medial malleolus
0.670 0.330 0.000
S06 Intracranial injury
0.670 0.330 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.669 0.330 0.000
N28.1 Cyst of kidney, acquired
0.669 0.331 0.000
Z46 Fitting and adjustment of other devices
0.669 0.331 0.000
N60-N64 Disorders of breast
0.669 0.331 0.000
D32 Benign neoplasm of meninges
0.668 0.332 0.000
N18.0 End-stage renal disease
0.667 0.332 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.667 0.333 0.000
J84 Other interstitial pulmonary diseases
0.667 0.333 0.000
S81.0 Open wound of knee
0.666 0.334 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.665 0.335 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.665 0.335 0.000
T39.4 Antirheumatics, not elsewhere classified
0.665 0.335 0.000
T39.2 Pyrazolone derivatives
0.665 0.335 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.665 0.335 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.664 0.336 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.664 0.336 0.000
X60-X84 Intentional self-harm
0.663 0.337 0.000
B91 Sequelae of poliomyelitis
0.663 0.337 0.000
I67.1 Cerebral aneurysm, nonruptured
0.662 0.337 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.662 0.338 0.000
M89 Other disorders of bone
0.661 0.338 0.000
D55-D59 Haemolytic anaemias
0.661 0.339 0.000
I67.2 Cerebral atherosclerosis
0.661 0.339 0.000
D22.9 Melanocytic naevi, unspecified
0.660 0.339 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.660 0.339 0.000
T43.9 Psychotropic drug, unspecified
0.660 0.340 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.660 0.340 0.000
T43.6 Psychostimulants with abuse potential
0.660 0.340 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.660 0.340 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.660 0.340 0.000
V80-V89 Other land transport accidents
0.659 0.341 0.000
H54 Blindness and low vision
0.659 0.341 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.659 0.341 0.000
Chapter VIII Diseases of the ear and mastoid process
0.658 0.342 0.000
M65-M68 Disorders of synovium and tendon
0.658 0.342 0.000
Z45.8 Adjustment and management of other implanted devices
0.657 0.343 0.000
T45.0 Antiallergic and antiemetic drugs
0.656 0.344 0.000
C62 Malignant neoplasm of testis
0.656 0.344 0.000
N03 Chronic nephritic syndrome
0.656 0.344 0.000
M51 Other intervertebral disk disorders
0.656 0.344 0.000
S99 Other and unspecified injuries of ankle and foot
0.655 0.345 0.000
Z65 Problems related to other psychosocial circumstances
0.654 0.345 0.000
Z64 Problems related to certain psychosocial circumstances
0.654 0.345 0.000
Z62 Other problems related to upbringing
0.654 0.345 0.000
Z61 Problems related to negative life events in childhood
0.654 0.345 0.000
Z59 Problems related to housing and economic circumstances
0.654 0.345 0.000
Z58 Problems related to physical environment
0.654 0.345 0.000
Z56 Problems related to employment and unemployment
0.654 0.345 0.000
Z55 Problems related to education and literacy
0.654 0.345 0.000
I08 Multiple valve diseases
0.654 0.346 0.000
C53 Malignant neoplasm of cervix uteri
0.653 0.347 0.000
I34.1 Mitral (valve) prolapse
0.652 0.348 0.000
M79.8 Other specified soft tissue disorders
0.651 0.349 0.000
H16 Keratitis
0.651 0.349 0.000
D30.3 Bladder
0.651 0.349 0.000
F29 Unspecified nonorganic psychosis
0.651 0.349 0.000
D23.2 Skin of ear and external auricular canal
0.650 0.350 0.000
D23.0 Skin of lip
0.650 0.350 0.000
F17.9 Unspecified mental and behavioural disorder
0.650 0.350 0.000
F17.8 Other mental and behavioural disorders
0.650 0.350 0.000
F17.7 Residual and late-onset psychotic disorder
0.650 0.350 0.000
F17.6 Amnesic syndrome
0.650 0.350 0.000
F17.5 Psychotic disorder
0.650 0.350 0.000
F17.4 Withdrawal state with delirium
0.650 0.350 0.000
F17.3 Withdrawal state
0.650 0.350 0.000
F17.0 Acute intoxication
0.650 0.350 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.649 0.350 0.000
J60-J70 Lung diseases due to external agents
0.649 0.351 0.000
M85 Other disorders of bone density and structure
0.648 0.352 0.000
M83 Adult osteomalacia
0.648 0.352 0.000
M82 Osteoporosis in diseases classified elsewhere
0.648 0.352 0.000
S91 Open wound of ankle and foot
0.648 0.352 0.000
D69 Purpura and other haemorrhagic conditions
0.648 0.352 0.000
M79.10 Myalgia (Multiple sites)
0.647 0.353 0.000
I23 Certain current complications following acute myocardial infarction
0.647 0.353 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.647 0.353 0.000
S40-S49 Injuries to the shoulder and upper arm
0.646 0.354 0.000
T42.4 Benzodiazepines
0.645 0.355 0.000
C56 Malignant neoplasm of ovary
0.645 0.355 0.000
J09-J18 Influenza and pneumonia
0.645 0.355 0.000
D22.4 Melanocytic naevi of scalp and neck
0.644 0.355 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.644 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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