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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6757751
log Bayes Factor = 15.3429
Chromosome 2   position 228,925,597  (GRCh37) Explore rs6757751 on Ensembl!
Variant rs6757751 is part of Cluster X0227

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
I50.0 Congestive heart failure
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
I20-I25 Ischaemic heart diseases
0.993 0.007 0.000
S60-S69 Injuries to the wrist and hand
0.992 0.008 0.000
R94 Abnormal results of function studies
0.991 0.009 0.000
Chapter I Certain infectious and parasitic diseases
0.990 0.010 0.000
I25 Chronic ischaemic heart disease
0.987 0.013 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.984 0.016 0.000
R94.5 Abnormal results of liver function studies
0.981 0.019 0.000
S20-S29 Injuries to the thorax
0.980 0.020 0.000
G90-G99 Other disorders of the nervous system
0.976 0.024 0.000
J09-J18 Influenza and pneumonia
0.976 0.024 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.970 0.030 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.968 0.032 0.000
E10-E14 Diabetes mellitus
0.967 0.033 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.967 0.033 0.000
E10 Insulin-dependent diabetes mellitus
0.964 0.036 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.963 0.037 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.963 0.037 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.962 0.038 0.000
A30-A49 Other bacterial diseases
0.957 0.043 0.000
E10.9 Without complications
0.951 0.049 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.949 0.051 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.948 0.052 0.000
B95-B98 Bacterial, viral and other infectious agents
0.947 0.053 0.000
J18 Pneumonia, organism unspecified
0.944 0.056 0.000
S90-S99 Injuries to the ankle and foot
0.939 0.061 0.000
I50.9 Heart failure, unspecified
0.938 0.062 0.000
Chapter XX External causes of morbidity and mortality
0.935 0.065 0.000
J18.1 Lobar pneumonia, unspecified
0.935 0.065 0.000
I60-I69 Cerebrovascular diseases
0.935 0.065 0.000
S27 Injury of other and unspecified intrathoracic organs
0.923 0.077 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.922 0.078 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.922 0.078 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.915 0.085 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.914 0.086 0.000
G82 Paraplegia and tetraplegia
0.909 0.091 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.908 0.092 0.000
G20-G26 Extrapyramidal and movement disorders
0.908 0.092 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.907 0.093 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.903 0.097 0.000
M50-M54 Other dorsopathies
0.902 0.098 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.901 0.099 0.000
M54 Dorsalgia
0.901 0.099 0.000
S40-S49 Injuries to the shoulder and upper arm
0.900 0.100 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.896 0.104 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.889 0.111 0.000
I50.1 Left ventricular failure
0.887 0.113 0.000
M54.9 Dorsalgia, unspecified
0.886 0.114 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.883 0.117 0.000
G93 Other disorders of brain
0.882 0.118 0.000
I51 Complications and ill-defined descriptions of heart disease
0.875 0.125 0.000
S32 Fracture of lumbar spine and pelvis
0.874 0.126 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.873 0.127 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.870 0.130 0.000
R22.2 Localised swelling, mass and lump, trunk
0.869 0.131 0.000
I34 Nonrheumatic mitral valve disorders
0.869 0.131 0.000
A41 Other septicaemia
0.868 0.132 0.000
I25.5 Ischaemic cardiomyopathy
0.864 0.136 0.000
R21 Rash and other nonspecific skin eruption
0.864 0.136 0.000
I22 Subsequent myocardial infarction
0.862 0.138 0.000
M40-M43 Deforming dorsopathies
0.861 0.139 0.000
I69 Sequelae of cerebrovascular disease
0.861 0.139 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.859 0.140 0.000
S70-S79 Injuries to the hip and thigh
0.857 0.143 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.856 0.144 0.000
I61 Intracerebral haemorrhage
0.855 0.145 0.000
G90 Disorders of autonomic nervous system
0.854 0.146 0.000
D80-D89 Certain disorders involving the immune mechanism
0.853 0.147 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.851 0.149 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.851 0.149 0.000
S62 Fracture at wrist and hand level
0.851 0.149 0.000
I47 Paroxysmal tachycardia
0.850 0.150 0.000
S64 Injury of nerves at wrist and hand level
0.850 0.150 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.848 0.152 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.847 0.153 0.000
G82.2 Paraplegia, unspecified
0.847 0.153 0.000
I05-I09 Chronic rheumatic heart diseases
0.845 0.155 0.000
I24 Other acute ischaemic heart diseases
0.841 0.159 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.840 0.160 0.000
E14 Unspecified diabetes mellitus
0.839 0.161 0.000
S92 Fracture of foot, except ankle
0.838 0.162 0.000
A49 Bacterial infection of unspecified site
0.838 0.162 0.000
G54 Nerve root and plexus disorders
0.838 0.162 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.838 0.162 0.000
R23 Other skin changes
0.836 0.164 0.000
G20 Parkinson's disease
0.832 0.168 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.832 0.168 0.000
E10.1 With ketoacidosis
0.831 0.169 0.000
R82 Other abnormal findings in urine
0.830 0.170 0.000
B15-B19 Viral hepatitis
0.829 0.171 0.000
J14 Pneumonia due to Haemophilus influenzae
0.829 0.171 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.828 0.171 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.828 0.172 0.000
G59.0 Diabetic mononeuropathy
0.827 0.173 0.000
E11 Non-insulin-dependent diabetes mellitus
0.826 0.174 0.000
J81 Pulmonary oedema
0.825 0.175 0.000
G62 Other polyneuropathies
0.823 0.177 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.820 0.180 0.000
I31 Other diseases of pericardium
0.819 0.181 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.819 0.181 0.000
G83 Other paralytic syndromes
0.818 0.182 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.818 0.182 0.000
G30-G32 Other degenerative diseases of the nervous system
0.817 0.182 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.817 0.183 0.000
G93.0 Cerebral cysts
0.816 0.184 0.000
I37 Pulmonary valve disorders
0.814 0.186 0.000
R22.1 Localised swelling, mass and lump, neck
0.813 0.187 0.000
E10.4 With neurological complications
0.811 0.189 0.000
T79-T79 Certain early complications of trauma
0.810 0.190 0.000
D86 Sarcoidosis
0.808 0.192 0.000
S27.2 Traumatic heamopneumothorax
0.806 0.194 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.804 0.196 0.000
A80-A89 Viral infections of the central nervous system
0.804 0.196 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.802 0.198 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.801 0.199 0.000
J60-J70 Lung diseases due to external agents
0.799 0.201 0.000
B35-B49 Mycoses
0.799 0.201 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.797 0.203 0.000
M54.4 Lumbago with sciatica
0.794 0.206 0.000
R94.2 Abnormal results of pulmonary function studies
0.792 0.208 0.000
R20 Disturbances of skin sensation
0.791 0.209 0.000
T23 Burn and corrosion of wrist and hand
0.791 0.209 0.000
J40-J47 Chronic lower respiratory diseases
0.787 0.213 0.000
J00-J06 Acute upper respiratory infections
0.786 0.214 0.000
S63.3 Traumatic rupture of ligament of wrist and carpus
0.786 0.214 0.000
S20 Superficial injury of thorax
0.786 0.214 0.000
G57 Mononeuropathies of lower limb
0.784 0.216 0.000
Y84.8 Other medical procedures
0.784 0.216 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.784 0.216 0.000
M41 Scoliosis
0.783 0.217 0.000
M54.6 Pain in thoracic spine
0.780 0.220 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.778 0.222 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.778 0.222 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.778 0.222 0.000
I49 Other cardiac arrhythmias
0.776 0.224 0.000
G96 Other disorders of central nervous system
0.775 0.225 0.000
S22.4 Multiple fractures of ribs
0.774 0.226 0.000
E11.3 With ophthalmic complications
0.773 0.227 0.000
R94.3 Abnormal results of cardiovascular function studies
0.773 0.227 0.000
R50-R69 General symptoms and signs
0.773 0.227 0.000
W20-W49 Exposure to inanimate mechanical forces
0.771 0.229 0.000
T00-T07 Injuries involving multiple body regions
0.770 0.230 0.000
G62.9 Polyneuropathy, unspecified
0.768 0.232 0.000
W00-W19 Falls
0.768 0.232 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.766 0.234 0.000
S27.3 Other injuries of lung
0.764 0.236 0.000
S42 Fracture of shoulder and upper arm
0.763 0.237 0.000
G82.5 Tetraplegia, unspecified
0.763 0.237 0.000
E14.3 With ophthalmic complications
0.762 0.238 0.000
S22.1 Multiple fractures of thoracic spine
0.762 0.238 0.000
M54.3 Sciatica
0.761 0.239 0.000
S22.5 Flail chest
0.757 0.243 0.000
I47.1 Supraventricular tachycardia
0.756 0.244 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.756 0.244 0.000
S72 Fracture of femur
0.755 0.245 0.000
I45 Other conduction disorders
0.755 0.245 0.000
G80 Infantile cerebral palsy
0.755 0.245 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.753 0.247 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.752 0.248 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.751 0.249 0.000
R52 Pain, not elsewhere classified
0.751 0.249 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.750 0.250 0.000
R59 Enlarged lymph nodes
0.750 0.250 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.749 0.251 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.749 0.251 0.000
A39 Meningococcal infection
0.745 0.254 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.745 0.255 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.744 0.256 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.744 0.256 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.742 0.258 0.000
S27.0 Traumatic pneumothorax
0.741 0.259 0.000
R22.0 Localised swelling, mass and lump, head
0.740 0.260 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.740 0.260 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.739 0.261 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.739 0.261 0.000
E10.8 With unspecified complications
0.738 0.262 0.000
S32.5 Fracture of pubis
0.737 0.263 0.000
S36 Injury of intra-abdominal organs
0.737 0.263 0.000
I05 Rheumatic mitral valve diseases
0.736 0.264 0.000
I51.8 Other ill-defined heart diseases
0.734 0.266 0.000
D86.0 Sarcoidosis of lung
0.734 0.266 0.000
I34.1 Mitral (valve) prolapse
0.734 0.266 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.734 0.266 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.732 0.268 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.732 0.268 0.000
Q80-Q89 Other congenital malformations
0.732 0.268 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.731 0.269 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.731 0.269 0.000
I25.3 Aneurysm of heart
0.729 0.270 0.000
R82.8 Abnormal findings on cytological and histological examination of urine
0.729 0.271 0.000
I36 Nonrheumatic tricuspid valve disorders
0.729 0.271 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.728 0.272 0.000
Chapter XXII Codes for special purposes
0.727 0.273 0.000
J15.2 Pneumonia due to staphylococcus
0.727 0.273 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.726 0.274 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.726 0.274 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.725 0.275 0.000
A40 Streptococcal septicaemia
0.724 0.276 0.000
S65 Injury of blood vessels at wrist and hand level
0.724 0.276 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.724 0.276 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.723 0.277 0.000
S68 Traumatic amputation of wrist and hand
0.722 0.278 0.000
J95-J99 Other diseases of the respiratory system
0.722 0.278 0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)
0.722 0.278 0.000
A49.0 Staphylococcal infection, unspecified
0.721 0.279 0.000
S90 Superficial injury of ankle and foot
0.721 0.279 0.000
S50-S59 Injuries to the elbow and forearm
0.720 0.280 0.000
T20 Burn and corrosion of head and neck
0.719 0.281 0.000
I51.7 Cardiomegaly
0.719 0.281 0.000
A46 Erysipelas
0.718 0.282 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.718 0.282 0.000
M41.9 Scoliosis, unspecified
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
G95 Other diseases of spinal cord
0.716 0.284 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.716 0.284 0.000
S64.4 Injury of digital nerve of other finger
0.716 0.284 0.000
S72.0 Fracture of neck of femur
0.715 0.285 0.000
J86 Pyothorax
0.715 0.285 0.000
R60 Oedema, not elsewhere classified
0.714 0.286 0.000
G50 Disorders of trigeminal nerve
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
M43 Other deforming dorsopathies
0.714 0.286 0.000
S22.2 Fracture of sternum
0.713 0.287 0.000
I23 Certain current complications following acute myocardial infarction
0.712 0.288 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.711 0.289 0.000
R94.7 Abnormal results of other endocrine function studies
0.711 0.289 0.000
R94.6 Abnormal results of thyroid function studies
0.711 0.289 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.711 0.289 0.000
R94.0 Abnormal results of function studies of central nervous system
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.709 0.290 0.000
B50-B64 Protozoal diseases
0.709 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.709 0.290 0.000
A75-A79 Rickettsioses
0.709 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.709 0.290 0.000
A65-A69 Other spirochaetal diseases
0.709 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.709 0.290 0.000
A15-A19 Tuberculosis
0.709 0.290 0.000
M91-M94 Chondropathies
0.709 0.290 0.000
R52.0 Acute pain
0.709 0.291 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.709 0.291 0.000
S27.1 Traumatic haemothorax
0.709 0.291 0.000
M86-M90 Other osteopathies
0.709 0.291 0.000
E10.5 With peripheral circulatory complications
0.709 0.291 0.000
G58 Other mononeuropathies
0.708 0.292 0.000
M54.2 Cervicalgia
0.708 0.292 0.000
J30-J39 Other diseases of upper respiratory tract
0.708 0.292 0.000
R23.2 Flushing
0.708 0.292 0.000
I25.6 Silent myocardial ischaemia
0.708 0.292 0.000
I25.4 Coronary artery aneurysm
0.708 0.292 0.000
D55-D59 Haemolytic anaemias
0.708 0.292 0.000
I31.9 Disease of pericardium, unspecified
0.706 0.294 0.000
S69 Other and unspecified injuries of wrist and hand
0.706 0.294 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.706 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.705 0.295 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.705 0.295 0.000
B17 Other acute viral hepatitis
0.705 0.295 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.704 0.296 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.704 0.296 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.703 0.297 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.702 0.298 0.000
S26 Injury of heart
0.702 0.298 0.000
S25 Injury of blood vessels of thorax
0.702 0.298 0.000
S24 Injury of nerves and spinal cord at thorax level
0.702 0.298 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.702 0.298 0.000
S21 Open wound of thorax
0.702 0.298 0.000
R23.8 Other and unspecified skin changes
0.702 0.298 0.000
I24.1 Dressler's syndrome
0.701 0.299 0.000
S30.2 Contusion of external genital organs
0.701 0.299 0.000
E11.4 With neurological complications
0.701 0.299 0.000
G54.6 Phantom limb syndrome with pain
0.701 0.299 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.700 0.300 0.000
R54 Senility
0.700 0.300 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.700 0.300 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.700 0.300 0.000
G92 Toxic encephalopathy
0.700 0.300 0.000
J17 Pneumonia in diseases classified elsewhere
0.700 0.300 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.700 0.300 0.000
J12 Viral pneumonia, not elsewhere classified
0.700 0.300 0.000
J09 Influenza due to certain identified influenza virus
0.700 0.300 0.000
R59.0 Localised enlarged lymph nodes
0.699 0.301 0.000
M54.1 Radiculopathy
0.699 0.301 0.000
A41.8 Other specified septicaemia
0.698 0.302 0.000
Chapter II Neoplasms
0.698 0.302 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.698 0.302 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.698 0.302 0.000
E10.3 With ophthalmic complications
0.698 0.302 0.000
B99-B99 Other infectious diseases
0.697 0.303 0.000
I46 Cardiac arrest
0.696 0.304 0.000
S67 Crushing injury of wrist and hand
0.696 0.304 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.695 0.304 0.000
S37 Injury of urinary and pelvic organs
0.695 0.304 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.695 0.304 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.695 0.304 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.695 0.304 0.000
S31 Open wound of abdomen, lower back and pelvis
0.695 0.304 0.000
J15.1 Pneumonia due to Pseudomonas
0.695 0.305 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.694 0.306 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.693 0.306 0.000
E12 Malnutrition-related diabetes mellitus
0.693 0.307 0.000
S62.5 Fracture of thumb
0.693 0.307 0.000
X20-X29 Contact with venomous animals and plants
0.693 0.307 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.692 0.308 0.000
E14.5 With peripheral circulatory complications
0.692 0.308 0.000
S93.0 Dislocation of ankle joint
0.691 0.309 0.000
E10.7 With multiple complications
0.691 0.309 0.000
E10.6 With other specified complications
0.691 0.309 0.000
E10.2 With renal complications
0.691 0.309 0.000
E10.0 With coma
0.691 0.309 0.000
M60-M63 Disorders of muscles
0.691 0.309 0.000
J84 Other interstitial pulmonary diseases
0.690 0.310 0.000
S30.0 Contusion of lower back and pelvis
0.690 0.310 0.000
G52 Disorders of other cranial nerves
0.690 0.310 0.000
G70-G73 Diseases of myoneural junction and muscle
0.689 0.310 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.689 0.311 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.689 0.311 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.689 0.311 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.689 0.311 0.000
J02 Acute pharyngitis
0.689 0.311 0.000
S61 Open wound of wrist and hand
0.689 0.311 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.689 0.311 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.688 0.311 0.000
G40-G47 Episodic and paroxysmal disorders
0.688 0.312 0.000
S72.00 Fracture of neck of femur (closed)
0.687 0.313 0.000
A48 Other bacterial diseases, not elsewhere classified
0.686 0.314 0.000
A44 Bartonellosis
0.686 0.314 0.000
A43 Nocardiosis
0.686 0.314 0.000
A42 Actinomycosis
0.686 0.314 0.000
A37 Whooping cough
0.686 0.314 0.000
A36 Diphtheria
0.686 0.314 0.000
A32 Listeriosis
0.686 0.314 0.000
A31 Infection due to other mycobacteria
0.686 0.314 0.000
A30 Leprosy [Hansen's disease]
0.686 0.314 0.000
A38 Scarlet fever
0.686 0.314 0.000
A35 Other tetanus
0.686 0.314 0.000
A34 Obstetrical tetanus
0.686 0.314 0.000
A33 Tetanus neonatorum
0.686 0.314 0.000
E50-E64 Other nutritional deficiencies
0.686 0.314 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.686 0.314 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.685 0.315 0.000
X10-X19 Contact with heat and hot substances
0.685 0.315 0.000
G57.6 Lesion of plantar nerve
0.685 0.315 0.000
I24.8 Other forms of acute ischaemic heart disease
0.685 0.315 0.000
W50-W64 Exposure to animate mechanical forces
0.684 0.316 0.000
R90.0 Intracranial space-occupying lesion
0.684 0.316 0.000
R81 Glycosuria
0.683 0.317 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.683 0.317 0.000
I60 Subarachnoid haemorrhage
0.683 0.317 0.000
E16 Other disorders of pancreatic internal secretion
0.682 0.318 0.000
D86.9 Sarcoidosis, unspecified
0.682 0.318 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.681 0.318 0.000
G25 Other extrapyramidal and movement disorders
0.681 0.319 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.681 0.319 0.000
T66-T78 Other and unspecified effects of external causes
0.681 0.319 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.680 0.320 0.000
I37.1 Pulmonary valve insufficiency
0.680 0.320 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.680 0.320 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.680 0.320 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.680 0.320 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.680 0.320 0.000
S32.1 Fracture of sacrum
0.680 0.320 0.000
S92.0 Fracture of calcaneus
0.680 0.320 0.000
S22.40 Multiple fractures of ribs (closed)
0.678 0.322 0.000
I08 Multiple valve diseases
0.678 0.322 0.000
S62.3 Fracture of other metacarpal bone
0.677 0.323 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.677 0.323 0.000
Y84.6 Urinary catheterisation
0.677 0.323 0.000
J18.8 Other pneumonia, organism unspecified
0.677 0.323 0.000
J18.2 Hypostatic pneumonia, unspecified
0.677 0.323 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.676 0.324 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.676 0.324 0.000
S91 Open wound of ankle and foot
0.676 0.324 0.000
I21 Acute myocardial infarction
0.676 0.324 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.675 0.325 0.000
S32.0 Fracture of lumbar vertebra
0.675 0.325 0.000
R82.7 Abnormal findings on microbiological examination of urine
0.675 0.325 0.000
E40-E46 Malnutrition
0.675 0.325 0.000
G54.0 Brachial plexus disorders
0.675 0.325 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.674 0.326 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.674 0.326 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.674 0.326 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.674 0.326 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.674 0.326 0.000
S98 Traumatic amputation of ankle and foot
0.673 0.326 0.000
S97 Crushing injury of ankle and foot
0.673 0.326 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.673 0.326 0.000
S95 Injury of blood vessels at ankle and foot level
0.673 0.326 0.000
S94 Injury of nerves at ankle and foot level
0.673 0.326 0.000
W06 Fall involving bed
0.673 0.327 0.000
G83.4 Cauda equina syndrome
0.672 0.328 0.000
G93.9 Disorder of brain, unspecified
0.672 0.328 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.672 0.328 0.000
Y00-Y09 Assault
0.671 0.329 0.000
I47.0 Reentry ventricular arrhythmia
0.671 0.329 0.000
Y35-Y36 Legal intervention and operations of war
0.671 0.329 0.000
Y10-Y34 Event of undetermined intent
0.671 0.329 0.000
X85-X99 Assault
0.671 0.329 0.000
X30-X39 Exposure to forces of nature
0.671 0.329 0.000
X00-X09 Exposure to smoke, fire and flames
0.671 0.329 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.671 0.329 0.000
W75-W84 Other accidental threats to breathing
0.671 0.329 0.000
W65-W74 Accidental drowning and submersion
0.671 0.329 0.000
V98-V99 Other and unspecified transport accidents
0.671 0.329 0.000
V95-V97 Air and space transport accidents
0.671 0.329 0.000
V90-V94 Water transport accidents
0.671 0.329 0.000
V70-V79 Bus occupant injured in transport accident
0.671 0.329 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.671 0.329 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.671 0.329 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.671 0.329 0.000
V01-V09 Pedestrian injured in transport accident
0.671 0.329 0.000
A86 Unspecified viral encephalitis
0.670 0.330 0.000
J80 Adult respiratory distress syndrome
0.670 0.330 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.670 0.330 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.670 0.330 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.669 0.331 0.000
J44 Other chronic obstructive pulmonary disease
0.668 0.332 0.000
I33 Acute and subacute endocarditis
0.667 0.333 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.667 0.333 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.667 0.333 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.666 0.334 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.664 0.336 0.000
S92.5 Fracture of other toe
0.664 0.336 0.000
G93.6 Cerebral oedema
0.664 0.336 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.664 0.336 0.000
S99 Other and unspecified injuries of ankle and foot
0.663 0.336 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.663 0.337 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.663 0.337 0.000
T23.2 Burn of second degree of wrist and hand
0.663 0.337 0.000
R82.9 Other and unspecified abnormal finding in urine
0.663 0.337 0.000
J90-J94 Other diseases of pleura
0.662 0.338 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.662 0.338 0.000
S27.9 Injury of unspecified intrathoracic organ
0.662 0.338 0.000
S27.8 Injury of other specified intrathoracic organs
0.662 0.338 0.000
S27.7 Multiple injuries of intrathoracic organs
0.662 0.338 0.000
S27.6 Injury of pleura
0.662 0.338 0.000
S27.5 Injury of thoracic trachea
0.662 0.338 0.000
S27.4 Injury of bronchus
0.662 0.338 0.000
M80-M85 Disorders of bone density and structure
0.662 0.338 0.000
S63.1 Dislocation finger
0.661 0.339 0.000
S63.7 Sprain and strain of other and unspecified parts of hand
0.661 0.339 0.000
S63.5 Sprain and strain of wrist
0.661 0.339 0.000
S63.2 Multiple dislocations of fingers
0.661 0.339 0.000
S63.0 Dislocation of wrist
0.661 0.339 0.000
V40-V49 Car occupant injured in transport accident
0.661 0.339 0.000
T25 Burn and corrosion of ankle and foot
0.661 0.339 0.000
T21 Burn and corrosion of trunk
0.661 0.339 0.000
M40 Kyphosis and lordosis
0.661 0.339 0.000
Y84.2 Radiological procedure and radiotherapy
0.659 0.341 0.000
C34 Malignant neoplasm of bronchus and lung
0.658 0.342 0.000
R40 Somnolence, stupor and coma
0.657 0.342 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.657 0.343 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.657 0.343 0.000
S22.10 Multiple fractures of thoracic spine (closed)
0.657 0.343 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.656 0.344 0.000
I49.9 Cardiac arrhythmia, unspecified
0.656 0.344 0.000
I49.8 Other specified cardiac arrhythmias
0.656 0.344 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.655 0.344 0.000
M53 Other dorsopathies, not elsewhere classified
0.655 0.345 0.000
B35 Dermatophytosis
0.655 0.345 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.655 0.345 0.000
V10-V19 Pedal cyclist injured in transport accident
0.654 0.346 0.000
R59.9 Enlarged lymph nodes, unspecified
0.654 0.346 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.654 0.346 0.000
S30.1 Contusion of abdominal wall
0.653 0.347 0.000
G24 Dystonia
0.653 0.347 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.653 0.347 0.000
X50-X57 Overexertion, travel and privation
0.653 0.347 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.653 0.347 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.652 0.348 0.000
S92.4 Fracture of great toe
0.652 0.348 0.000
G91 Hydrocephalus
0.652 0.348 0.000
G82.4 Spastic tetraplegia
0.652 0.348 0.000
G82.3 Flaccid tetraplegia
0.652 0.348 0.000
G82.0 Flaccid paraplegia
0.652 0.348 0.000
I67 Other cerebrovascular diseases
0.651 0.349 0.000
S22.9 Fracture of bony thorax, part unspecified
0.651 0.349 0.000
S22.8 Fracture of other parts of bony thorax
0.651 0.349 0.000
G23 Other degenerative diseases of basal ganglia
0.651 0.349 0.000
G21 Secondary Parkinsonism
0.651 0.349 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.651 0.349 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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