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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6779678
log Bayes Factor = 12.6162
Chromosome 3   position 149,225,903  (GRCh37) Explore rs6779678 on Ensembl!
Variant rs6779678 is part of Cluster X0245

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K80 Cholelithiasis
1.000 0.000 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
1.000 0.000 0.000
K82 Other diseases of gallbladder
1.000 0.000 0.000
K82.4 Cholesterolosis of gallbladder
1.000 0.000 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
1.000 0.000 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.999 0.001 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.999 0.001 0.000
K81 Cholecystitis
0.997 0.003 0.000
K83 Other diseases of biliary tract
0.983 0.017 0.000
K81.1 Chronic cholecystitis
0.978 0.022 0.000
K83.8 Other specified diseases of biliary tract
0.966 0.034 0.000
K81.0 Acute cholecystitis
0.952 0.048 0.000
K86 Other diseases of pancreas
0.946 0.054 0.000
K86.8 Other specified diseases of pancreas
0.936 0.064 0.000
K80.8 Other cholelithiasis
0.907 0.093 0.000
K83.0 Cholangitis
0.893 0.107 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.863 0.137 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.857 0.143 0.000
M50-M54 Other dorsopathies
0.856 0.144 0.000
M45-M49 Spondylopathies
0.852 0.148 0.000
K82.2 Perforation of gallbladder
0.849 0.150 0.000
M47 Spondylosis
0.847 0.153 0.000
M54 Dorsalgia
0.843 0.157 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.840 0.160 0.000
M54.5 Low back pain
0.835 0.165 0.000
S90-S99 Injuries to the ankle and foot
0.830 0.170 0.000
S60-S69 Injuries to the wrist and hand
0.827 0.173 0.000
M47.8 Other spondylosis
0.824 0.176 0.000
M50 Cervical disk disorders
0.824 0.176 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.821 0.179 0.000
S70-S79 Injuries to the hip and thigh
0.816 0.184 0.000
M20-M25 Other joint disorders
0.813 0.187 0.000
# Top node
0.811 0.189 0.000
M47.9 Spondylosis, unspecified
0.811 0.189 0.000
M54.56 Low back pain (Lumbar region)
0.811 0.189 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.809 0.191 0.000
K82.1 Hydrops of gallbladder
0.805 0.195 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.805 0.195 0.000
K85 Acute pancreatitis
0.801 0.198 0.000
Chapter XI Diseases of the digestive system
0.796 0.204 0.000
M50.0 Cervical disk disorder with myelopathy
0.794 0.206 0.000
S40-S49 Injuries to the shoulder and upper arm
0.792 0.208 0.000
E10-E14 Diabetes mellitus
0.791 0.209 0.000
M47.82 Other spondylosis (Cervical region)
0.791 0.209 0.000
T93 Sequelae of injuries of lower limb
0.789 0.211 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.787 0.213 0.000
M24 Other specific joint derangements
0.787 0.213 0.000
E70-E90 Metabolic disorders
0.783 0.217 0.000
K81.9 Cholecystitis, unspecified
0.783 0.217 0.000
E78.0 Pure hypercholesterolaemia
0.781 0.219 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.781 0.219 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.774 0.226 0.000
E11 Non-insulin-dependent diabetes mellitus
0.772 0.228 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.771 0.228 0.000
S00-S09 Injuries to the head
0.766 0.234 0.000
E11.9 Without complications
0.766 0.234 0.000
M47.86 Other spondylosis (Lumbar region)
0.765 0.235 0.000
S92 Fracture of foot, except ankle
0.763 0.237 0.000
M40-M43 Deforming dorsopathies
0.760 0.239 0.000
Chapter XXII Codes for special purposes
0.760 0.240 0.000
K83.9 Disease of biliary tract, unspecified
0.758 0.242 0.000
M53 Other dorsopathies, not elsewhere classified
0.758 0.242 0.000
M23 Internal derangement of knee
0.754 0.246 0.000
S40 Superficial injury of shoulder and upper arm
0.751 0.249 0.000
T93.2 Sequelae of other fractures of lower limb
0.750 0.250 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.747 0.253 0.000
S90 Superficial injury of ankle and foot
0.744 0.256 0.000
K82.3 Fistula of gallbladder
0.742 0.257 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.739 0.261 0.000
K70-K77 Diseases of liver
0.739 0.261 0.000
M54.54 Low back pain-Thoracic
0.737 0.263 0.000
S02 Fracture of skull and facial bones
0.735 0.265 0.000
K82.9 Disease of gallbladder, unspecified
0.726 0.274 0.000
M43 Other deforming dorsopathies
0.723 0.277 0.000
M24.0 Loose body in joint
0.723 0.277 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.721 0.279 0.000
M23.8 Other internal derangements of knee
0.720 0.280 0.000
S70 Superficial injury of hip and thigh
0.719 0.281 0.000
M54.57 Low back pain (Lumbosacral region)
0.718 0.282 0.000
K80.3 Calculus of bile duct with cholangitis
0.717 0.283 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.717 0.283 0.000
K82.0 Obstruction of gallbladder
0.717 0.283 0.000
S72 Fracture of femur
0.717 0.283 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.716 0.284 0.000
K81.8 Other cholecystitis
0.715 0.285 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.711 0.289 0.000
K70 Alcoholic liver disease
0.709 0.291 0.000
M54.4 Lumbago with sciatica
0.709 0.291 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.708 0.292 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.708 0.292 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.708 0.292 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.706 0.294 0.000
K83.5 Biliary cyst
0.705 0.295 0.000
K83.4 Spasm of sphincter of Oddi
0.705 0.295 0.000
K83.3 Fistula of bile duct
0.705 0.295 0.000
K83.2 Perforation of bile duct
0.705 0.295 0.000
E10 Insulin-dependent diabetes mellitus
0.703 0.297 0.000
S31 Open wound of abdomen, lower back and pelvis
0.701 0.299 0.000
E87.5 Hyperkalaemia
0.700 0.300 0.000
S92.0 Fracture of calcaneus
0.699 0.301 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.696 0.304 0.000
M91-M94 Chondropathies
0.696 0.304 0.000
T90 Sequelae of injuries of head
0.695 0.305 0.000
M43.1 Spondylolisthesis
0.695 0.305 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.690 0.310 0.000
K86.9 Disease of pancreas, unspecified
0.689 0.311 0.000
K86.1 Other chronic pancreatitis
0.688 0.312 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.688 0.312 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.688 0.312 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.687 0.313 0.000
M49 Spondylopathies in diseases classified elsewhere
0.686 0.314 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.686 0.314 0.000
M48 Other spondylopathies
0.684 0.316 0.000
K80.4 Calculus of bile duct with cholecystitis
0.682 0.318 0.000
T91 Sequelae of injuries of neck and trunk
0.673 0.326 0.000
M50.2 Other cervical disk displacement
0.673 0.327 0.000
T00-T07 Injuries involving multiple body regions
0.672 0.328 0.000
E11.4 With neurological complications
0.671 0.329 0.000
K70.9 Alcoholic liver disease, unspecified
0.670 0.330 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.670 0.330 0.000
M54.6 Pain in thoracic spine
0.669 0.331 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.668 0.332 0.000
O85-O92 Complications predominantly related to the puerperium
0.667 0.333 0.000
S60 Superficial injury of wrist and hand
0.667 0.333 0.000
S79 Other and unspecified injuries of hip and thigh
0.666 0.334 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.666 0.334 0.000
M21 Other acquired deformities of limbs
0.664 0.336 0.000
S02.4 Fracture of malar and maxillary bones
0.662 0.338 0.000
M24.1 Other articular cartilage disorders
0.661 0.338 0.000
K82.8 Other specified diseases of gallbladder
0.658 0.342 0.000
M00-M03 Infectious arthropathies
0.656 0.344 0.000
S90.8 Other superficial injuries of ankle and foot
0.656 0.344 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.655 0.345 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.655 0.345 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.655 0.345 0.000
S92.00 Fracture of calcaneus (closed)
0.653 0.347 0.000
E10.2 With renal complications
0.653 0.347 0.000
K72 Hepatic failure, not elsewhere classified
0.652 0.348 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.649 0.351 0.000
S06 Intracranial injury
0.648 0.352 0.000
E11.8 With unspecified complications
0.647 0.353 0.000
U80 Agent resistant to penicillin and related antibiotics
0.647 0.353 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.647 0.353 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.644 0.356 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.644 0.356 0.000
E20-E35 Disorders of other endocrine glands
0.642 0.358 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.642 0.358 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.640 0.360 0.000
K85.9 Acute pancreatitis, unspecified
0.639 0.361 0.000
E78.6 Lipoprotein deficiency
0.638 0.362 0.000
M54.9 Dorsalgia, unspecified
0.638 0.362 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.637 0.363 0.000
M23.4 Loose body in knee
0.637 0.363 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.637 0.363 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.636 0.364 0.000
T98 Sequelae of other and unspecified effects of external causes
0.636 0.364 0.000
S67 Crushing injury of wrist and hand
0.635 0.365 0.000
M05-M14 Inflammatory polyarthropathies
0.633 0.367 0.000
S65 Injury of blood vessels at wrist and hand level
0.631 0.369 0.000
M34 Systemic sclerosis
0.630 0.370 0.000
S63.6 Sprain and strain of finger(s)
0.629 0.371 0.000
M24.02 Loose body in joint (Upper arm)
0.627 0.373 0.000
S20-S29 Injuries to the thorax
0.627 0.373 0.000
S30.0 Contusion of lower back and pelvis
0.627 0.373 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.626 0.374 0.000
E13 Other specified diabetes mellitus
0.625 0.374 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.625 0.375 0.000
M24.07 Loose body in joint (Ankle and foot)
0.625 0.375 0.000
S40.8 Other superficial injuries of shoulder and upper arm
0.623 0.377 0.000
M47.2 Other spondylosis with radiculopathy
0.623 0.377 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.623 0.377 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.622 0.378 0.000
M47.84 Other spondylosis (Thoracic region)
0.620 0.380 0.000
T33-T35 Frostbite
0.619 0.381 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.619 0.381 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.619 0.381 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.619 0.381 0.000
S05 Injury of eye and orbit
0.618 0.382 0.000
S36 Injury of intra-abdominal organs
0.613 0.386 0.000
T21 Burn and corrosion of trunk
0.611 0.388 0.000
M92 Other juvenile osteochondrosis
0.611 0.389 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.609 0.391 0.000
S72.0 Fracture of neck of femur
0.608 0.392 0.000
T66-T78 Other and unspecified effects of external causes
0.608 0.392 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.608 0.392 0.000
K70.0 Alcoholic fatty liver
0.608 0.392 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.607 0.393 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.607 0.393 0.000
S42 Fracture of shoulder and upper arm
0.605 0.394 0.000
S02.2 Fracture of nasal bones
0.605 0.395 0.000
M54.8 Other dorsalgia
0.605 0.395 0.000
M54.0 Panniculitis affecting regions of neck and back
0.605 0.395 0.000
M24.6 Ankylosis of joint
0.604 0.396 0.000
K85.1 Biliary acute pancreatitis
0.603 0.397 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.603 0.397 0.000
T95 Sequelae of burns, corrosions and frostbite
0.602 0.397 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.602 0.397 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.602 0.397 0.000
M24.5 Contracture of joint
0.602 0.398 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.602 0.398 0.000
E78.8 Other disorders of lipoprotein metabolism
0.602 0.398 0.000
S31.1 Open wound of abdominal wall
0.602 0.398 0.000
M33 Dermatopolymyositis
0.602 0.398 0.000
S02.0 Fracture of vault of skull
0.601 0.399 0.000
M46 Other inflammatory spondylopathies
0.600 0.400 0.000
M54.53 Low back pain-Cervicothoracic
0.599 0.401 0.000
M54.52 Low back pain-Cervical
0.599 0.401 0.000
M54.51 Low back pain-Occipit-atl-axl
0.599 0.401 0.000
E78.2 Mixed hyperlipidaemia
0.598 0.402 0.000
S90.3 Contusion of other and unspecified parts of foot
0.598 0.402 0.000
T25 Burn and corrosion of ankle and foot
0.598 0.402 0.000
S70.1 Contusion of thigh
0.597 0.403 0.000
M54.2 Cervicalgia
0.596 0.404 0.000
M23.9 Internal derangement of knee, unspecified
0.596 0.404 0.000
S02.1 Fracture of base of skull
0.595 0.405 0.000
S98 Traumatic amputation of ankle and foot
0.595 0.405 0.000
S97 Crushing injury of ankle and foot
0.595 0.405 0.000
S95 Injury of blood vessels at ankle and foot level
0.595 0.405 0.000
S94 Injury of nerves at ankle and foot level
0.595 0.405 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.595 0.405 0.000
E10.1 With ketoacidosis
0.595 0.405 0.000
S71 Open wound of hip and thigh
0.594 0.406 0.000
U51 Admission status on psychiatric patients
0.593 0.407 0.000
K73 Chronic hepatitis, not elsewhere classified
0.593 0.407 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.591 0.409 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.591 0.409 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.591 0.409 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.591 0.409 0.000
M50.9 Cervical disk disorder, unspecified
0.590 0.409 0.000
M50.8 Other cervical disk disorders
0.590 0.409 0.000
M21.6 Other acquired deformities of ankle and foot
0.589 0.411 0.000
M25 Other joint disorders, not elsewhere classified
0.589 0.411 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.589 0.411 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.589 0.411 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.589 0.411 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.588 0.412 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.587 0.413 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.586 0.413 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.586 0.414 0.000
M47.89 Other spondylosis (Site unspecified)
0.586 0.414 0.000
S78 Traumatic amputation of hip and thigh
0.585 0.415 0.000
S77 Crushing injury of hip and thigh
0.585 0.415 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.585 0.415 0.000
S75 Injury of blood vessels at hip and thigh level
0.585 0.415 0.000
S74 Injury of nerves at hip and thigh level
0.585 0.415 0.000
K72.0 Acute and subacute hepatic failure
0.584 0.415 0.000
T92 Sequelae of injuries of upper limb
0.583 0.417 0.000
M50.1 Cervical disk disorder with radiculopathy
0.583 0.417 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.583 0.417 0.000
M32 Systemic lupus erythematosus
0.583 0.417 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.582 0.418 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.582 0.418 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.582 0.418 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.582 0.418 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.582 0.418 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.582 0.418 0.000
S37 Injury of urinary and pelvic organs
0.581 0.419 0.000
S99 Other and unspecified injuries of ankle and foot
0.580 0.420 0.000
M86-M90 Other osteopathies
0.580 0.420 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.580 0.420 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.580 0.420 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.580 0.420 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.580 0.420 0.000
S92.5 Fracture of other toe
0.579 0.421 0.000
S72.4 Fracture of lower end of femur
0.578 0.421 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.578 0.422 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.577 0.423 0.000
S40.0 Contusion of shoulder and upper arm
0.577 0.423 0.000
M06 Other rheumatoid arthritis
0.575 0.425 0.000
K85.8 Other acute pancreatitis
0.575 0.425 0.000
K85.3 Drug-induced acute pancreatitis
0.575 0.425 0.000
K85.2 Alcohol-induced acute pancreatitis
0.575 0.425 0.000
K85.0 Idiopathic acute pancreatitis
0.575 0.425 0.000
M25.7 Osteophyte
0.573 0.427 0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot
0.572 0.428 0.000
O86 Other puerperal infections
0.572 0.428 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.572 0.428 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.572 0.428 0.000
S92.1 Fracture of talus
0.570 0.430 0.000
S48 Traumatic amputation of shoulder and upper arm
0.568 0.432 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.568 0.432 0.000
S44 Injury of nerves at shoulder and upper arm level
0.568 0.432 0.000
S47 Crushing injury of shoulder and upper arm
0.568 0.432 0.000
E12 Malnutrition-related diabetes mellitus
0.567 0.432 0.000
T79-T79 Certain early complications of trauma
0.567 0.432 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.567 0.433 0.000
S92.2 Fracture of other tarsal bone(s)
0.566 0.434 0.000
S41 Open wound of shoulder and upper arm
0.566 0.434 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.566 0.434 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.566 0.434 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.566 0.434 0.000
T93.0 Sequelae of open wound of lower limb
0.566 0.434 0.000
E87.7 Fluid overload
0.565 0.434 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.565 0.435 0.000
E24 Cushing's syndrome
0.565 0.435 0.000
M24.9 Joint derangement, unspecified
0.564 0.436 0.000
M24.7 Protrusio acetabuli
0.564 0.436 0.000
S60.0 Contusion of finger(s) without damage to nail
0.563 0.436 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.563 0.437 0.000
M23.5 Chronic instability of knee
0.563 0.437 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.563 0.437 0.000
E84 Cystic fibrosis
0.562 0.438 0.000
E79 Disorders of purine and pyrimidine metabolism
0.562 0.438 0.000
E77 Disorders of glycoprotein metabolism
0.562 0.438 0.000
E76 Disorders of glycosaminoglycan metabolism
0.562 0.438 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.562 0.438 0.000
E72 Other disorders of amino-acid metabolism
0.562 0.438 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.562 0.438 0.000
E70 Disorders of aromatic amino-acid metabolism
0.562 0.438 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.562 0.438 0.000
S30.2 Contusion of external genital organs
0.561 0.439 0.000
E78.3 Hyperchylomicronaemia
0.560 0.440 0.000
T90.5 Sequelae of intracranial injury
0.559 0.441 0.000
S79.9 Unspecified injury of hip and thigh
0.559 0.441 0.000
E73 Lactose intolerance
0.557 0.443 0.000
M25.78 Osteophyte (Other)
0.556 0.444 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.556 0.444 0.000
E11.7 With multiple complications
0.554 0.446 0.000
M23.0 Cystic meniscus
0.553 0.447 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.552 0.448 0.000
S70.0 Contusion of hip
0.552 0.448 0.000
M45 Ankylosing spondylitis
0.552 0.448 0.000
M60-M63 Disorders of muscles
0.551 0.449 0.000
M48.0 Spinal stenosis
0.550 0.450 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.550 0.450 0.000
T90.9 Sequelae of unspecified injury of head
0.550 0.450 0.000
S68 Traumatic amputation of wrist and hand
0.550 0.450 0.000
S08 Traumatic amputation of part of head
0.549 0.450 0.000
S07 Crushing injury of head
0.549 0.450 0.000
S04 Injury of cranial nerves
0.549 0.450 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.549 0.450 0.000
M24.2 Disorder of ligament
0.549 0.450 0.000
M50.3 Other cervical disk degeneration
0.549 0.451 0.000
E50-E64 Other nutritional deficiencies
0.549 0.451 0.000
O90 Complications of the puerperium, not elsewhere classified
0.548 0.452 0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level
0.548 0.452 0.000
S92.9 Fracture of foot, unspecified
0.547 0.453 0.000
S92.7 Multiple fractures of foot
0.547 0.453 0.000
S92.4 Fracture of great toe
0.547 0.453 0.000
S31.8 Open wound of other and unspecified parts of abdomen
0.547 0.453 0.000
T01 Open wounds involving multiple body regions
0.547 0.453 0.000
M54.55 Low back pain (Thoracolumbar region)
0.546 0.454 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.545 0.454 0.000
M42 Spinal osteochondrosis
0.545 0.455 0.000
S72.1 Pertrochanteric fracture
0.545 0.455 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.544 0.456 0.000
M53.9 Dorsopathy, unspecified
0.543 0.457 0.000
M53.8 Other specified dorsopathies
0.543 0.457 0.000
M53.2 Spinal instabilities
0.543 0.457 0.000
M53.1 Cervicobrachial syndrome
0.543 0.457 0.000
M53.0 Cervicocranial syndrome
0.543 0.457 0.000
S42.4 Fracture of lower end of humerus
0.543 0.457 0.000
M30 Polyarteritis nodosa and related conditions
0.543 0.457 0.000
M31 Other necrotising vasculopathies
0.542 0.458 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.542 0.458 0.000
E11.3 With ophthalmic complications
0.541 0.459 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.540 0.459 0.000
M23.1 Discoid meniscus (congenital)
0.539 0.461 0.000
E87.2 Acidosis
0.539 0.461 0.000
K86.3 Pseudocyst of pancreas
0.539 0.461 0.000
S40.7 Multiple superficial injuries of shoulder and upper arm
0.538 0.462 0.000
S06.2 Diffuse brain injury
0.538 0.462 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.537 0.463 0.000
S02.6 Fracture of mandible
0.537 0.463 0.000
E11.1 With ketoacidosis
0.537 0.463 0.000
E87.3 Alkalosis
0.537 0.463 0.000
E88 Other metabolic disorders
0.536 0.463 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.536 0.464 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.536 0.464 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.536 0.464 0.000
E87.4 Mixed disorder of acid-base balance
0.535 0.465 0.000
O16 Unspecified maternal hypertension
0.535 0.465 0.000
T09 Other injuries of spine and trunk, level unspecified
0.535 0.465 0.000
M23.49 Loose body in knee-Unspec lig/men
0.535 0.465 0.000
E22 Hyperfunction of pituitary gland
0.534 0.466 0.000
S90.7 Multiple superficial injuries of ankle and foot
0.534 0.466 0.000
S90.2 Contusion of toe(s) with damage to nail
0.534 0.466 0.000
S90.1 Contusion of toe(s) without damage to nail
0.534 0.466 0.000
S90.0 Contusion of ankle
0.534 0.466 0.000
M47.1 Other spondylosis with myelopathy
0.533 0.466 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.533 0.466 0.000
M06.9 Rheumatoid arthritis, unspecified
0.533 0.467 0.000
T90.8 Sequelae of other specified injuries of head
0.532 0.467 0.000
O85 Puerperal sepsis
0.532 0.468 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.532 0.468 0.000
S72.00 Fracture of neck of femur (closed)
0.530 0.469 0.000
K77 Liver disorders in diseases classified elsewhere
0.530 0.470 0.000
K71 Toxic liver disease
0.530 0.470 0.000
M43.0 Spondylolysis
0.530 0.470 0.000
M40 Kyphosis and lordosis
0.530 0.470 0.000
U80.1 Methicillin resistant agent
0.530 0.470 0.000
S92.3 Fracture of metatarsal bone
0.530 0.470 0.000
S02.3 Fracture of orbital floor
0.529 0.471 0.000
S02.7 Multiple fractures involving skull and facial bones
0.527 0.473 0.000
S42.0 Fracture of clavicle
0.527 0.473 0.000
S72.2 Subtrochanteric fracture
0.527 0.473 0.000
S02.8 Fractures of other skull and facial bones
0.526 0.474 0.000
E11.6 With other specified complications
0.526 0.474 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.526 0.474 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.526 0.474 0.000
M34.1 CR(E)ST syndrome
0.524 0.476 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.522 0.478 0.000
S91 Open wound of ankle and foot
0.522 0.478 0.000
T90.1 Sequelae of open wound of head
0.522 0.478 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.522 0.478 0.000
E74 Other disorders of carbohydrate metabolism
0.522 0.478 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.520 0.480 0.000
S20 Superficial injury of thorax
0.520 0.480 0.000
M92.7 Juvenile osteochondrosis of metatarsus
0.520 0.480 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.519 0.481 0.000
T19 Foreign body in genito-urinary tract
0.519 0.481 0.000
M43.9 Deforming dorsopathy, unspecified
0.518 0.481 0.000
M43.8 Other specified deforming dorsopathies
0.518 0.481 0.000
M43.6 Torticollis
0.518 0.481 0.000
M43.5 Other recurrent vertebral subluxation
0.518 0.481 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.518 0.481 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.518 0.481 0.000
M43.2 Other fusion of spine
0.518 0.481 0.000
E10.4 With neurological complications
0.518 0.482 0.000
M24.09 Loose body in joint (Site unspecified)
0.518 0.482 0.000
M24.08 Loose body in joint (Other)
0.518 0.482 0.000
M24.06 Loose body in joint-Lower leg
0.518 0.482 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.518 0.482 0.000
M24.04 Loose body in joint (Hand)
0.518 0.482 0.000
M24.03 Loose body in joint (Forearm)
0.518 0.482 0.000
M24.01 Loose body in joint (Shoulder region)
0.518 0.482 0.000
M24.00 Loose body in joint (Multiple sites)
0.518 0.482 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.518 0.482 0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis
0.517 0.483 0.000
T20 Burn and corrosion of head and neck
0.517 0.483 0.000
E40-E46 Malnutrition
0.517 0.483 0.000
E27 Other disorders of adrenal gland
0.516 0.483 0.000
U80.0 Penicillin resistant agent
0.516 0.483 0.000
K75 Other inflammatory liver diseases
0.516 0.484 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.516 0.484 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.516 0.484 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.516 0.484 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.516 0.484 0.000
O87 Venous complications in the puerperium
0.516 0.484 0.000
S70.8 Other superficial injuries of hip and thigh
0.516 0.484 0.000
S70.7 Multiple superficial injuries of hip and thigh
0.516 0.484 0.000
T11 Other injuries of upper limb, level unspecified
0.515 0.485 0.000
T91.1 Sequelae of fracture of spine
0.515 0.485 0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.514 0.486 0.000
K87.1 Disorders of pancreas in diseases classified elsewhere
0.514 0.486 0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.514 0.486 0.000
S72.9 Fracture of femur, part unspecified
0.514 0.486 0.000
S72.8 Fractures of other parts of femur
0.514 0.486 0.000
S72.7 Multiple fractures of femur
0.514 0.486 0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand
0.514 0.486 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.513 0.486 0.000
U51.0 Not Previously admitted to a psyciatric hospital
0.513 0.487 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.512 0.487 0.000
S02.20 Fracture of nasal bones (closed)
0.512 0.488 0.000
T68 Hypothermia
0.511 0.489 0.000
S27 Injury of other and unspecified intrathoracic organs
0.511 0.489 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.510 0.490 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.509 0.491 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.509 0.491 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.508 0.492 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.508 0.492 0.000
M54.44 Lumbago with sciatica-Thoracic
0.508 0.492 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.508 0.492 0.000
M54.42 Lumbago with sciatica-Cervical
0.508 0.492 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.508 0.492 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.508 0.492 0.000
U50 Level of care administered to neonates
0.508 0.492 0.000
U07 Emergency use of U07
0.508 0.492 0.000
U06 Emergency use of U06
0.508 0.492 0.000
U04 Severe acute respiratory syndrome [SARS]
0.508 0.492 0.000
U52 First in a series of a regular day/night admissions
0.508 0.492 0.000
E78.1 Pure hyperglyceridaemia
0.507 0.493 0.000
T17 Foreign body in respiratory tract
0.507 0.493 0.000
T14 Injury of unspecified body region
0.507 0.493 0.000
E13.9 Without complications
0.507 0.493 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.507 0.493 0.000
S63.1 Dislocation finger
0.506 0.493 0.000
S63.7 Sprain and strain of other and unspecified parts of hand
0.506 0.493 0.000
S63.5 Sprain and strain of wrist
0.506 0.493 0.000
S63.3 Traumatic rupture of ligament of wrist and carpus
0.506 0.493 0.000
S63.2 Multiple dislocations of fingers
0.506 0.493 0.000
S63.0 Dislocation of wrist
0.506 0.493 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.506 0.494 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.506 0.494 0.000
O86.0 Infection of obstetric surgical wound
0.506 0.494 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.505 0.495 0.000
S02.00 Fracture of vault of skull (closed)
0.505 0.495 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.504 0.496 0.000
E10.7 With multiple complications
0.504 0.496 0.000
E10.6 With other specified complications
0.504 0.496 0.000
E10.0 With coma
0.504 0.496 0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.504 0.496 0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis
0.503 0.496 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.503 0.497 0.000
T94.1 Sequelae of injuries, not specified by body region
0.503 0.497 0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis
0.503 0.497 0.000
S31.5 Open wound of other and unspecified external genital organs
0.503 0.497 0.000
S31.4 Open wound of vagina and vulva
0.503 0.497 0.000
S31.3 Open wound of scrotum and testes
0.503 0.497 0.000
S31.2 Open wound of penis
0.503 0.497 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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