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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs68108873
log Bayes Factor = 8.01808
Chromosome 2   position 170,121,734  (GRCh37) Explore rs68108873 on Ensembl!
Variant rs68108873 is part of Cluster X0230

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
G90-G99 Other disorders of the nervous system
0.982 0.018 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.977 0.023 0.000
W00-W19 Falls
0.975 0.025 0.000
M50-M54 Other dorsopathies
0.974 0.026 0.000
M40-M43 Deforming dorsopathies
0.965 0.035 0.000
M45-M49 Spondylopathies
0.962 0.038 0.000
Chapter II Neoplasms
0.958 0.042 0.000
M54 Dorsalgia
0.956 0.044 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.954 0.046 0.000
G93 Other disorders of brain
0.951 0.049 0.000
A30-A49 Other bacterial diseases
0.950 0.050 0.000
W19 Unspecified fall
0.950 0.050 0.000
M43 Other deforming dorsopathies
0.940 0.060 0.000
Y43 Primarily systemic agents
0.936 0.064 0.000
A00-A09 Intestinal infectious diseases
0.935 0.065 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.925 0.074 0.000
B95-B98 Bacterial, viral and other infectious agents
0.925 0.075 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.925 0.075 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.922 0.078 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.921 0.079 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.920 0.080 0.000
M43.1 Spondylolisthesis
0.919 0.081 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.918 0.082 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.917 0.083 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.914 0.086 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.910 0.090 0.000
C71 Malignant neoplasm of brain
0.908 0.092 0.000
Y52 Agents primarily affecting the cardiovascular system
0.907 0.093 0.000
W19.4 Street and highway
0.906 0.094 0.000
M47 Spondylosis
0.903 0.097 0.000
E10-E14 Diabetes mellitus
0.898 0.102 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.898 0.102 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.898 0.102 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.895 0.105 0.000
M46 Other inflammatory spondylopathies
0.891 0.109 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.888 0.112 0.000
M54.5 Low back pain
0.887 0.113 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.882 0.118 0.000
A49 Bacterial infection of unspecified site
0.879 0.121 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.877 0.123 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.876 0.124 0.000
E14 Unspecified diabetes mellitus
0.876 0.124 0.000
D00-D09 In situ neoplasms
0.875 0.125 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.873 0.127 0.000
Y43.3 Other antineoplastic drugs
0.872 0.128 0.000
W19.2 School, other institution and public administrative area
0.870 0.130 0.000
E20-E35 Disorders of other endocrine glands
0.868 0.132 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.867 0.133 0.000
T51 Toxic effect of alcohol
0.864 0.136 0.000
M80-M85 Disorders of bone density and structure
0.862 0.138 0.000
X60-X84 Intentional self-harm
0.858 0.142 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.856 0.144 0.000
M54.59 Low back pain (Site unspecified)
0.856 0.144 0.000
V10-V19 Pedal cyclist injured in transport accident
0.856 0.144 0.000
C78.7 Secondary malignant neoplasm of liver
0.854 0.146 0.000
M51 Other intervertebral disk disorders
0.854 0.146 0.000
A04 Other bacterial intestinal infections
0.853 0.147 0.000
E16 Other disorders of pancreatic internal secretion
0.853 0.147 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.853 0.147 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.853 0.147 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.850 0.150 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.850 0.150 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.849 0.151 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.849 0.151 0.000
A08 Viral and other specified intestinal infections
0.846 0.154 0.000
M54.9 Dorsalgia, unspecified
0.845 0.155 0.000
E14.9 Without complications
0.843 0.157 0.000
M86-M90 Other osteopathies
0.842 0.158 0.000
G93.8 Other specified disorders of brain
0.842 0.158 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.840 0.160 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.839 0.161 0.000
C71.9 Brain, unspecified
0.839 0.161 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.838 0.162 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.835 0.165 0.000
Chapter XXII Codes for special purposes
0.834 0.166 0.000
G93.6 Cerebral oedema
0.829 0.171 0.000
T43.2 Other and unspecified antidepressants
0.828 0.172 0.000
T51.0 Ethanol
0.825 0.175 0.000
C51-C58 Malignant neoplasms of female genital organs
0.824 0.176 0.000
A41 Other septicaemia
0.824 0.176 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.822 0.178 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.820 0.180 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.819 0.181 0.000
M54.1 Radiculopathy
0.818 0.182 0.000
Chapter V Mental and behavioural disorders
0.818 0.182 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.809 0.191 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.808 0.192 0.000
E16.2 Hypoglycaemia, unspecified
0.806 0.194 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.806 0.194 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.806 0.194 0.000
G90 Disorders of autonomic nervous system
0.805 0.195 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.804 0.196 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.802 0.198 0.000
E27 Other disorders of adrenal gland
0.800 0.200 0.000
M54.4 Lumbago with sciatica
0.800 0.200 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.799 0.201 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.799 0.201 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.797 0.203 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.797 0.203 0.000
T39.1 4-Aminophenol derivatives
0.795 0.205 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.794 0.206 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.794 0.206 0.000
A49.0 Staphylococcal infection, unspecified
0.793 0.207 0.000
S90-S99 Injuries to the ankle and foot
0.792 0.208 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.792 0.208 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.792 0.208 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.790 0.210 0.000
V90-V94 Water transport accidents
0.789 0.211 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.788 0.212 0.000
A80-A89 Viral infections of the central nervous system
0.786 0.214 0.000
B99-B99 Other infectious diseases
0.786 0.214 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.785 0.215 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.784 0.216 0.000
G93.4 Encephalopathy, unspecified
0.783 0.217 0.000
C71.2 Temporal lobe
0.781 0.219 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.781 0.219 0.000
V40-V49 Car occupant injured in transport accident
0.781 0.219 0.000
Y00-Y09 Assault
0.781 0.219 0.000
A08.4 Viral intestinal infection, unspecified
0.780 0.220 0.000
M47.9 Spondylosis, unspecified
0.779 0.221 0.000
B35-B49 Mycoses
0.778 0.222 0.000
W19.3 Sports and athletics area
0.777 0.223 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.775 0.225 0.000
G95 Other diseases of spinal cord
0.774 0.226 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.773 0.227 0.000
M47.2 Other spondylosis with radiculopathy
0.773 0.227 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.772 0.228 0.000
S10-S19 Injuries to the neck
0.772 0.228 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.770 0.229 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.770 0.230 0.000
G61 Inflammatory polyneuropathy
0.769 0.231 0.000
X10-X19 Contact with heat and hot substances
0.767 0.233 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.766 0.234 0.000
G93.5 Compression of brain
0.765 0.235 0.000
Q60-Q64 Congenital malformations of the urinary system
0.764 0.236 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.763 0.236 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.763 0.237 0.000
S40-S49 Injuries to the shoulder and upper arm
0.762 0.238 0.000
T79-T79 Certain early complications of trauma
0.762 0.238 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.762 0.238 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.761 0.239 0.000
M60-M63 Disorders of muscles
0.760 0.240 0.000
M47.8 Other spondylosis
0.760 0.240 0.000
X20-X29 Contact with venomous animals and plants
0.759 0.241 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.759 0.241 0.000
M91-M94 Chondropathies
0.758 0.242 0.000
T86 Failure and rejection of transplanted organs and tissues
0.757 0.243 0.000
D04 Carcinoma in situ of skin
0.757 0.243 0.000
C71.1 Frontal lobe
0.757 0.243 0.000
E14.3 With ophthalmic complications
0.757 0.243 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.756 0.244 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.755 0.245 0.000
W13 Fall from, out of or through building or structure
0.754 0.246 0.000
M05-M14 Inflammatory polyarthropathies
0.753 0.247 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.752 0.248 0.000
T36 Poisoning by systemic antibiotics
0.751 0.249 0.000
Y43.4 Immunosuppressive agents
0.750 0.250 0.000
Y49.2 Other and unspecified antidepressants
0.748 0.252 0.000
G63.2 Diabetic polyneuropathy
0.747 0.253 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.746 0.254 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.746 0.254 0.000
C78.2 Secondary malignant neoplasm of pleura
0.745 0.255 0.000
W15 Fall from cliff
0.745 0.255 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.743 0.257 0.000
C56 Malignant neoplasm of ovary
0.743 0.257 0.000
E10 Insulin-dependent diabetes mellitus
0.743 0.257 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.742 0.258 0.000
C15-C26 Malignant neoplasms of digestive organs
0.740 0.260 0.000
M00-M03 Infectious arthropathies
0.740 0.260 0.000
G50 Disorders of trigeminal nerve
0.738 0.262 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.737 0.262 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.736 0.264 0.000
M49 Spondylopathies in diseases classified elsewhere
0.736 0.264 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.735 0.265 0.000
Y57 Other and unspecified drugs and medicaments
0.733 0.266 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.733 0.267 0.000
Y52.1 Calcium-channel blockers
0.733 0.267 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.732 0.268 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.731 0.269 0.000
M54.16 Radiculopathy (Lumbar region)
0.730 0.270 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.728 0.272 0.000
G96 Other disorders of central nervous system
0.728 0.272 0.000
A48 Other bacterial diseases, not elsewhere classified
0.727 0.272 0.000
X50-X57 Overexertion, travel and privation
0.727 0.273 0.000
A49.1 Streptococcal infection, unspecified
0.725 0.275 0.000
T42.4 Benzodiazepines
0.724 0.276 0.000
G93.9 Disorder of brain, unspecified
0.724 0.276 0.000
C71.3 Parietal lobe
0.724 0.276 0.000
M43.0 Spondylolysis
0.722 0.278 0.000
G93.2 Benign intracranial hypertension
0.722 0.278 0.000
B65-B83 Helminthiases
0.721 0.279 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.719 0.281 0.000
M80 Osteoporosis with pathological fracture
0.719 0.281 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.719 0.281 0.000
Y48 Anaesthetics and therapeutic gases
0.719 0.281 0.000
G62 Other polyneuropathies
0.719 0.281 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.719 0.281 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
A49.9 Bacterial infection, unspecified
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
Y59 Other and unspecified vaccines and biological substances
0.715 0.284 0.000
Y58 Bacterial vaccines
0.715 0.284 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.715 0.284 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.284 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.715 0.284 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.715 0.284 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.714 0.286 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.713 0.287 0.000
E23 Hypofunction and other disorders of pituitary gland
0.713 0.287 0.000
W17 Other fall from one level to another
0.712 0.288 0.000
M89 Other disorders of bone
0.711 0.289 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.711 0.289 0.000
S70-S79 Injuries to the hip and thigh
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
M82 Osteoporosis in diseases classified elsewhere
0.709 0.291 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.709 0.291 0.000
M43.19 Spondylolisthesis (Site unspecified)
0.708 0.292 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.707 0.293 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.707 0.293 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.707 0.293 0.000
G58 Other mononeuropathies
0.706 0.294 0.000
F60-F69 Disorders of adult personality and behaviour
0.706 0.294 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.704 0.296 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.704 0.296 0.000
G92 Toxic encephalopathy
0.704 0.296 0.000
M54.57 Low back pain (Lumbosacral region)
0.704 0.296 0.000
S92 Fracture of foot, except ankle
0.703 0.297 0.000
G30-G32 Other degenerative diseases of the nervous system
0.701 0.299 0.000
T43.9 Psychotropic drug, unspecified
0.700 0.300 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.700 0.300 0.000
T43.6 Psychostimulants with abuse potential
0.700 0.300 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.700 0.300 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.700 0.300 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.700 0.300 0.000
W18 Other fall on same level
0.699 0.301 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.699 0.301 0.000
W14 Fall from tree
0.699 0.301 0.000
W12 Fall on and from scaffolding
0.699 0.301 0.000
W11 Fall on and from ladder
0.699 0.301 0.000
W09 Fall involving playground equipment
0.699 0.301 0.000
W08 Fall involving other furniture
0.699 0.301 0.000
W05 Fall involving wheelchair
0.699 0.301 0.000
W04 Fall while being carried or supported by other persons
0.699 0.301 0.000
W00 Fall on same level involving ice and snow
0.699 0.301 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.699 0.301 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.698 0.302 0.000
Y42.5 Other oestrogens and progestogens
0.697 0.303 0.000
B07 Viral warts
0.697 0.303 0.000
S50-S59 Injuries to the elbow and forearm
0.696 0.304 0.000
E27.2 Addisonian crisis
0.694 0.305 0.000
Y44 Agents primarily affecting blood constituents
0.693 0.306 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.694 0.306 0.000
M42 Spinal osteochondrosis
0.691 0.308 0.000
M40 Kyphosis and lordosis
0.691 0.308 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.691 0.308 0.000
A04.5 Campylobacter enteritis
0.691 0.309 0.000
T40.2 Other opioids
0.690 0.310 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.689 0.311 0.000
V80-V89 Other land transport accidents
0.689 0.311 0.000
Q61 Cystic kidney disease
0.689 0.311 0.000
G57 Mononeuropathies of lower limb
0.689 0.311 0.000
W06 Fall involving bed
0.688 0.312 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.688 0.312 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.687 0.313 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.687 0.313 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.686 0.314 0.000
M54.8 Other dorsalgia
0.685 0.315 0.000
M54.0 Panniculitis affecting regions of neck and back
0.685 0.315 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.685 0.315 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.685 0.315 0.000
C71.0 Cerebrum, except lobes and ventricles
0.684 0.316 0.000
T23 Burn and corrosion of wrist and hand
0.684 0.316 0.000
C45 Mesothelioma
0.683 0.317 0.000
M41 Scoliosis
0.682 0.318 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.682 0.318 0.000
G93.7 Reye's syndrome
0.682 0.318 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.682 0.318 0.000
A44 Bartonellosis
0.681 0.319 0.000
A43 Nocardiosis
0.681 0.319 0.000
A42 Actinomycosis
0.681 0.319 0.000
A40 Streptococcal septicaemia
0.681 0.319 0.000
A39 Meningococcal infection
0.681 0.319 0.000
A37 Whooping cough
0.681 0.319 0.000
A36 Diphtheria
0.681 0.319 0.000
A32 Listeriosis
0.681 0.319 0.000
A31 Infection due to other mycobacteria
0.681 0.319 0.000
A30 Leprosy [Hansen's disease]
0.681 0.319 0.000
A38 Scarlet fever
0.681 0.319 0.000
A35 Other tetanus
0.681 0.319 0.000
A34 Obstetrical tetanus
0.681 0.319 0.000
A33 Tetanus neonatorum
0.681 0.319 0.000
W19.8 Other specified place
0.681 0.319 0.000
W19.5 Trade and service area
0.681 0.319 0.000
W19.0 Home
0.681 0.319 0.000
W19.7 Farm
0.681 0.319 0.000
W19.6 Industrial and construction area
0.681 0.319 0.000
W19.1 Residential institution
0.681 0.319 0.000
M54.6 Pain in thoracic spine
0.680 0.320 0.000
M85 Other disorders of bone density and structure
0.679 0.321 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.678 0.322 0.000
D04.7 Skin of lower limb, including hip
0.678 0.322 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.678 0.322 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.677 0.323 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.677 0.323 0.000
C80 Malignant neoplasm without specification of site
0.676 0.324 0.000
D03 Melanoma in situ
0.676 0.324 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.674 0.325 0.000
M43.9 Deforming dorsopathy, unspecified
0.674 0.326 0.000
M43.8 Other specified deforming dorsopathies
0.674 0.326 0.000
M43.6 Torticollis
0.674 0.326 0.000
M43.5 Other recurrent vertebral subluxation
0.674 0.326 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.674 0.326 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.674 0.326 0.000
M43.2 Other fusion of spine
0.674 0.326 0.000
M53 Other dorsopathies, not elsewhere classified
0.673 0.327 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.673 0.327 0.000
E50-E64 Other nutritional deficiencies
0.672 0.328 0.000
C49.0 Connective and soft tissue of head, face and neck
0.672 0.328 0.000
M47.82 Other spondylosis (Cervical region)
0.671 0.329 0.000
Y43.9 Primarily systemic agent, unspecified
0.671 0.329 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.671 0.329 0.000
Y43.6 Enzymes, not elsewhere classified
0.671 0.329 0.000
Y43.5 Acidifying and alkalising agents
0.671 0.329 0.000
Y43.2 Antineoplastic natural products
0.671 0.329 0.000
Y43.1 Antineoplastic antimetabolites
0.671 0.329 0.000
Y43.0 Antiallergic and antiemetic drugs
0.671 0.329 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.671 0.329 0.000
A07 Other protozoal intestinal diseases
0.670 0.329 0.000
A06 Amoebiasis
0.670 0.329 0.000
A05 Other bacterial foodborne intoxications
0.670 0.329 0.000
A03 Shigellosis
0.670 0.329 0.000
A02 Other Salmonella infections
0.670 0.329 0.000
A01 Typhoid and paratyphoid fevers
0.670 0.329 0.000
A00 Cholera
0.670 0.329 0.000
C20 Malignant neoplasm of rectum
0.670 0.330 0.000
G95.2 Cord compression, unspecified
0.670 0.330 0.000
M20-M25 Other joint disorders
0.670 0.330 0.000
S80-S89 Injuries to the knee and lower leg
0.669 0.331 0.000
M65-M68 Disorders of synovium and tendon
0.669 0.331 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.667 0.333 0.000
G61.0 Guillain-Barre syndrome
0.667 0.333 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.666 0.334 0.000
C52 Malignant neoplasm of vagina
0.666 0.334 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.665 0.335 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.664 0.336 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.664 0.336 0.000
C70 Malignant neoplasm of meninges
0.664 0.336 0.000
Q80-Q89 Other congenital malformations
0.663 0.337 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.663 0.337 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.663 0.337 0.000
T46.7 Peripheral vasodilators
0.663 0.337 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.663 0.337 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.663 0.337 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.663 0.337 0.000
T46.1 Calcium-channel blockers
0.663 0.337 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.663 0.337 0.000
T66-T78 Other and unspecified effects of external causes
0.662 0.338 0.000
E26 Hyperaldosteronism
0.661 0.339 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.661 0.339 0.000
X63.0 Home
0.661 0.339 0.000
Y42.9 Other and unspecified hormone antagonists
0.661 0.339 0.000
Y42.4 Oral contraceptives
0.661 0.339 0.000
Y42.2 Antithyroid drugs
0.661 0.339 0.000
Y42.1 Thyroid hormones and substitutes
0.661 0.339 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.661 0.339 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.660 0.340 0.000
G64 Other disorders of peripheral nervous system
0.660 0.340 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.659 0.340 0.000
E28 Ovarian dysfunction
0.659 0.340 0.000
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)
0.659 0.341 0.000
M43.15 Spondylolisthesis (Thoracolumbar region)
0.659 0.341 0.000
M43.14 Spondylolisthesis (Thoracic region)
0.659 0.341 0.000
M43.13 Spondylolisthesis (Cervicothoracic region)
0.659 0.341 0.000
M43.12 Spondylolisthesis (Cervical region)
0.659 0.341 0.000
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)
0.659 0.341 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.659 0.341 0.000
W07 Fall involving chair
0.659 0.341 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.658 0.342 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.658 0.342 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.658 0.342 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.658 0.342 0.000
T42.3 Barbiturates
0.658 0.342 0.000
T42.2 Succinimides and oxazolidinediones
0.658 0.342 0.000
T42.1 Iminostilbenes
0.658 0.342 0.000
T42.0 Hydantoin derivatives
0.658 0.342 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.658 0.342 0.000
M86 Osteomyelitis
0.657 0.343 0.000
A86 Unspecified viral encephalitis
0.657 0.343 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.657 0.343 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.656 0.344 0.000
T51.9 Alcohol, unspecified
0.656 0.344 0.000
T50.8 Diagnostic agents
0.655 0.344 0.000
T50.7 Analeptics and opioid receptor antagonists
0.655 0.344 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.655 0.344 0.000
T50.5 Appetite depressants
0.655 0.344 0.000
T50.4 Drugs affecting uric acid metabolism
0.655 0.344 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.655 0.344 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.655 0.344 0.000
T50.1 Loop [high-ceiling] diuretics
0.655 0.344 0.000
T50.0 Mineralocorticoids and their antagonists
0.655 0.344 0.000
G51 Facial nerve disorders
0.655 0.345 0.000
M51.8 Other specified intervertebral disk disorders
0.655 0.345 0.000
G91 Hydrocephalus
0.654 0.346 0.000
V20-V29 Motorcycle rider injured in transport accident
0.653 0.347 0.000
G81 Hemiplegia
0.653 0.347 0.000
T65 Toxic effect of other and unspecified substances
0.652 0.348 0.000
T62 Toxic effect of other noxious substances eaten as food
0.652 0.348 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.652 0.348 0.000
T60 Toxic effect of pesticides
0.652 0.348 0.000
T57 Toxic effect of other inorganic substances
0.652 0.348 0.000
T56 Toxic effect of metals
0.652 0.348 0.000
T54 Toxic effect of corrosive substances
0.652 0.348 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.652 0.348 0.000
T52 Toxic effect of organic solvents
0.652 0.348 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.652 0.348 0.000
T58 Toxic effect of carbon monoxide
0.652 0.348 0.000
T55 Toxic effect of soaps and detergents
0.652 0.348 0.000
G93.3 Postviral fatigue syndrome
0.652 0.348 0.000
F22 Persistent delusional disorders
0.652 0.348 0.000
Y40 Systemic antibiotics
0.652 0.348 0.000
W20-W49 Exposure to inanimate mechanical forces
0.651 0.349 0.000
C71.8 Overlapping lesion of brain
0.651 0.349 0.000
C71.7 Brain stem
0.651 0.349 0.000
C71.6 Cerebellum
0.651 0.349 0.000
C71.5 Cerebral ventricle
0.651 0.349 0.000
C71.4 Occipital lobe
0.651 0.349 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.650 0.349 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.650 0.349 0.000
Y52.7 Peripheral vasodilators
0.650 0.349 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.650 0.349 0.000
M25 Other joint disorders, not elsewhere classified
0.651 0.349 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.650 0.350 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.649 0.351 0.000
M15-M19 Arthrosis
0.649 0.351 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.647 0.353 0.000
Y54.3 Benzothiadiazine derivatives
0.647 0.353 0.000
E29 Testicular dysfunction
0.647 0.353 0.000
A41.8 Other specified septicaemia
0.647 0.353 0.000
Y45.8 Other analgesics and antipyretics
0.645 0.355 0.000
T87 Complications peculiar to reattachment and amputation
0.645 0.355 0.000
Y47.1 Benzodiazepines
0.644 0.356 0.000
M54.2 Cervicalgia
0.644 0.356 0.000
E12 Malnutrition-related diabetes mellitus
0.644 0.356 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.644 0.356 0.000
C46 Kaposi's sarcoma
0.644 0.356 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.643 0.357 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.642 0.358 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.642 0.358 0.000
E15 Nondiabetic hypoglycaemic coma
0.642 0.358 0.000
G20-G26 Extrapyramidal and movement disorders
0.641 0.359 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.640 0.360 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.640 0.360 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.640 0.360 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.639 0.361 0.000
S12 Fracture of neck
0.639 0.361 0.000
M46.8 Other specified inflammatory spondylopathies
0.638 0.361 0.000
M46.5 Other infective spondylopathies
0.638 0.361 0.000
M46.4 Discitis, unspecified
0.638 0.361 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.638 0.361 0.000
M46.2 Osteomyelitis of vertebra
0.638 0.361 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.638 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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