TreeWAS – Variant ID: rs6893858

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K29.5 Chronic gastritis, unspecified	0.016	0.984	0.000
Z12.1 Special screening examination for neoplasm of intestinal tract	0.009	0.991	0.000
C18.0 Caecum	0.006	0.994	0.000
C18 Malignant neoplasm of colon	0.006	0.994	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.994	0.006
C18.2 Ascending colon	0.006	0.994	0.000
C18.7 Sigmoid colon	0.006	0.994	0.000
K29.7 Gastritis, unspecified	0.006	0.994	0.000
Z12 Special screening examination for neoplasms	0.006	0.994	0.000
C18.3 Hepatic flexure	0.005	0.995	0.000
K29 Gastritis and duodenitis	0.005	0.995	0.000
Z12.0 Special screening examination for neoplasm of stomach	0.005	0.995	0.000
C18.9 Colon, unspecified	0.005	0.995	0.000
C18.8 Overlapping lesion of colon	0.005	0.995	0.000
C18.5 Splenic flexure	0.005	0.995	0.000
C18.1 Appendix	0.005	0.995	0.000
Z12.5 Special screening examination for neoplasm of prostate	0.005	0.995	0.000
C25 Malignant neoplasm of pancreas	0.005	0.995	0.000
C15-C26 Malignant neoplasms of digestive organs	0.005	0.995	0.000
C18.4 Transverse colon	0.005	0.995	0.000
C18.6 Descending colon	0.004	0.995	0.000
C25.9 Pancreas, unspecified	0.004	0.996	0.000
C25.0 Head of pancreas	0.004	0.996	0.000
Z12.9 Special screening examination for neoplasm, unspecified	0.004	0.996	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.004	0.996	0.000
Z12.6 Special screening examination for neoplasm of bladder	0.004	0.996	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.004	0.996	0.000
Z12.3 Special screening examination for neoplasm of breast	0.004	0.996	0.000
Z12.2 Special screening examination for neoplasm of respiratory organs	0.004	0.996	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.004	0.996	0.000
Y43 Primarily systemic agents	0.004	0.996	0.000
Y43.3 Other antineoplastic drugs	0.004	0.996	0.000
K29.4 Chronic atrophic gastritis	0.004	0.996	0.000
K29.0 Acute haemorrhagic gastritis	0.004	0.996	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.004	0.996	0.000
K29.9 Gastroduodenitis, unspecified	0.004	0.996	0.000
K29.2 Alcoholic gastritis	0.004	0.996	0.000
K29.3 Chronic superficial gastritis	0.004	0.996	0.000
C20 Malignant neoplasm of rectum	0.004	0.996	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.004	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.004	0.996	0.000
Y45.8 Other analgesics and antipyretics	0.004	0.996	0.000
C25.8 Overlapping lesion of pancreas	0.004	0.996	0.000
C25.7 Other parts of pancreas	0.004	0.996	0.000
C25.4 Endocrine pancreas	0.004	0.996	0.000
C25.3 Pancreatic duct	0.004	0.996	0.000
C25.2 Tail of pancreas	0.004	0.996	0.000
C25.1 Body of pancreas	0.004	0.996	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.004	0.996	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.004	0.996	0.000
C21 Malignant neoplasm of anus and anal canal	0.004	0.996	0.000
C17 Malignant neoplasm of small intestine	0.004	0.996	0.000
C23 Malignant neoplasm of gallbladder	0.004	0.996	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
C16 Malignant neoplasm of stomach	0.003	0.996	0.000
C77.2 Intra-abdominal lymph nodes	0.004	0.996	0.000
Y45.2 Propionic acid derivatives	0.003	0.996	0.000
C15 Malignant neoplasm of oesophagus	0.003	0.996	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.003	0.997	0.000
Y43.4 Immunosuppressive agents	0.003	0.997	0.000
Y45.1 Salicylates	0.003	0.997	0.000
Y45.0 Opioids and related analgesics	0.003	0.997	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
C22.1 Intrahepatic bile duct carcinoma	0.003	0.997	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.003	0.997	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.003	0.997	0.000
Y45.5 4-Aminophenol derivatives	0.003	0.997	0.000
Y45.4 Antirheumatics	0.003	0.997	0.000
N13 Obstructive and reflux uropathy	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.003	0.997	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.003	0.997	0.000
Y43.6 Enzymes, not elsewhere classified	0.003	0.997	0.000
Y43.5 Acidifying and alkalising agents	0.003	0.997	0.000
Y43.2 Antineoplastic natural products	0.003	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.003	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
S82.8 Fractures of other parts of lower leg	0.000	0.997	0.003
Y59 Other and unspecified vaccines and biological substances	0.003	0.997	0.000
Y58 Bacterial vaccines	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.997	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.003	0.997	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.003	0.997	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Y48 Anaesthetics and therapeutic gases	0.003	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.003	0.997	0.000
K29.1 Other acute gastritis	0.003	0.997	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.997	0.003
C16.9 Stomach, unspecified	0.003	0.997	0.000
C22.9 Liver, unspecified	0.003	0.997	0.000
C22.7 Other specified carcinomas of liver	0.003	0.997	0.000
C22.4 Other sarcomas of liver	0.003	0.997	0.000
C22.3 Angiosarcoma of liver	0.003	0.997	0.000
C22.2 Hepatoblastoma	0.003	0.997	0.000
C22.0 Liver cell carcinoma	0.003	0.997	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
Y52.7 Peripheral vasodilators	0.003	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
N10-N16 Renal tubulo-interstitial diseases	0.003	0.997	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.003	0.997	0.000
C15.9 Oesophagus, unspecified	0.003	0.997	0.000
M20.1 Hallux valgus (acquired)	0.003	0.997	0.000
N13.3 Other and unspecified hydronephrosis	0.003	0.997	0.000
Y57.5 X-ray contrast media	0.003	0.997	0.000
C17.9 Small intestine, unspecified	0.003	0.997	0.000
C17.8 Overlapping lesion of small intestine	0.003	0.997	0.000
C17.3 Meckel's diverticulum	0.003	0.997	0.000
C17.2 Ileum	0.003	0.997	0.000
C17.1 Jejunum	0.003	0.997	0.000
C17.0 Duodenum	0.003	0.997	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.003	0.997	0.000
C21.2 Cloacogenic zone	0.003	0.997	0.000
C21.1 Anal canal	0.003	0.997	0.000
C21.0 Anus, unspecified	0.003	0.997	0.000
C24.9 Biliary tract, unspecified	0.003	0.997	0.000
C24.8 Overlapping lesion of biliary tract	0.003	0.997	0.000
C24.1 Ampulla of Vater	0.003	0.997	0.000
C24.0 Extrahepatic bile duct	0.003	0.997	0.000
C26.9 Ill-defined sites within the digestive system	0.003	0.997	0.000
C26.8 Overlapping lesion of digestive system	0.003	0.997	0.000
C26.1 Spleen	0.003	0.997	0.000
C26.0 Intestinal tract, part unspecified	0.003	0.997	0.000
N13.8 Other obstructive and reflux uropathy	0.003	0.997	0.000
C16.8 Overlapping lesion of stomach	0.003	0.997	0.000
C16.6 Greater curvature of stomach, unspecified	0.003	0.997	0.000
C16.5 Lesser curvature of stomach, unspecified	0.003	0.997	0.000
C16.4 Pylorus	0.003	0.997	0.000
C16.3 Pyloric antrum	0.003	0.997	0.000
C16.2 Body of stomach	0.003	0.997	0.000
C16.1 Fundus of stomach	0.003	0.997	0.000
N10 Acute tubulo-interstitial nephritis	0.003	0.997	0.000
Y40 Systemic antibiotics	0.003	0.997	0.000
C15.8 Overlapping lesion of oesophagus	0.003	0.997	0.000
C15.4 Middle third of oesophagus	0.003	0.997	0.000
C15.3 Upper third of oesophagus	0.003	0.997	0.000
C15.2 Abdominal part of oesophagus	0.003	0.997	0.000
C15.1 Thoracic part of oesophagus	0.003	0.997	0.000
C15.0 Cervical part of oesophagus	0.003	0.997	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.003	0.997	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.003	0.997	0.000
K29.6 Other gastritis	0.003	0.997	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.003	0.997	0.000
D37.3 Appendix	0.003	0.997	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.997	0.000
Y57.8 Other drugs and medicaments	0.002	0.997	0.000
Y57.7 Vitamins, not elsewhere classified	0.002	0.997	0.000
Y57.6 Other diagnostic agents	0.002	0.997	0.000
Y57.4 Pharmaceutical excipients	0.002	0.997	0.000
Y57.3 Alcohol deterrents	0.002	0.997	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.997	0.000
Y57.1 Lipotropic drugs	0.002	0.997	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.997	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.002	0.997	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.002	0.997	0.000
N13.6 Pyonephrosis	0.002	0.997	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.002	0.997	0.000
N13.4 Hydroureter	0.002	0.997	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.003	0.997	0.000
S82.86 Maisonneuve's fracture	0.000	0.997	0.002
S82.81 Fractures of other parts of lower leg (open)	0.000	0.997	0.002
N11 Chronic tubulo-interstitial nephritis	0.002	0.997	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.002	0.997	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.997	0.000
Y41.5 Antiviral drugs	0.002	0.997	0.000
Y41.4 Anthelminthics	0.002	0.997	0.000
Y41.3 Other antiprotozoal drugs	0.002	0.997	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.997	0.000
Y41.1 Antimycobacterial drugs	0.002	0.997	0.000
Y41.0 Sulphonamides	0.002	0.997	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.997	0.000
Y44.7 Plasma substitutes	0.002	0.997	0.000
Y44.6 Natural blood and blood products	0.002	0.997	0.000
Y44.5 Thrombolytic drugs	0.002	0.997	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.997	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.997	0.000
Y44.2 Anticoagulants	0.002	0.997	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.997	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.997	0.000
Y46.8 Antispasticity drugs	0.002	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.002	0.997	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.997	0.000
Y46.5 Valproic acid	0.002	0.997	0.000
Y46.4 Iminostilbenes	0.002	0.997	0.000
Y46.3 Deoxybarbiturates	0.002	0.997	0.000
Y46.2 Hydantoin derivatives	0.002	0.997	0.000
Y46.1 Oxazolidinediones	0.002	0.997	0.000
Y46.0 Succinimides	0.002	0.997	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.997	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.997	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.997	0.000
Y47.4 Bromine compounds	0.002	0.997	0.000
Y47.3 Paraldehyde	0.002	0.997	0.000
Y47.2 Chloral derivatives	0.002	0.997	0.000
Y47.1 Benzodiazepines	0.002	0.997	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.997	0.000
Y48.5 Therapeutic gases	0.002	0.997	0.000
Y48.4 Anaesthetic, unspecified	0.002	0.997	0.000
Y48.3 Local anaesthetics	0.002	0.997	0.000
Y48.2 Other and unspecified general anaesthetics	0.002	0.997	0.000
Y48.1 Parenteral anaesthetics	0.002	0.997	0.000
Y48.0 Inhaled anaesthetics	0.002	0.997	0.000
Y49.9 Psychotropic drug, unspecified	0.002	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.997	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.997	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.997	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.997	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.997	0.000
Y49.2 Other and unspecified antidepressants	0.002	0.997	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.997	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.997	0.000
Y50.9 Central nervous system stimulant, unspecified	0.002	0.997	0.000
Y50.8 Other central nervous system stimulants	0.002	0.997	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.997	0.000
Y50.1 Opioid receptor antagonists	0.002	0.997	0.000
Y50.0 Analeptics	0.002	0.997	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
Y53.7 Emetics	0.002	0.997	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.997	0.000
Y53.5 Digestants	0.002	0.997	0.000
Y53.4 Other laxatives	0.002	0.997	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.997	0.000
Y53.2 Stimulant laxatives	0.002	0.997	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.997	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.997	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.997	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.997	0.000
Y54.7 Agents affecting calcification	0.002	0.997	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.997	0.000
Y54.5 Other diuretics	0.002	0.997	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.997	0.000
Y54.3 Benzothiadiazine derivatives	0.002	0.997	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.997	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.997	0.000
Y54.0 Mineralocorticoids	0.002	0.997	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.002	0.997	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.002	0.997	0.000
Y55.5 Anticommon cold drugs	0.002	0.997	0.000
Y55.4 Expectorants	0.002	0.997	0.000
Y55.3 Antitussives	0.002	0.997	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.002	0.997	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.002	0.997	0.000
Y55.0 Oxytocic drugs	0.002	0.997	0.000
Y56.9 Topical agent, unspecified	0.002	0.997	0.000
Y56.8 Other topical agents	0.002	0.997	0.000
Y56.7 Dental drugs, topically applied	0.002	0.997	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.997	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.997	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.997	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.997	0.000
Y56.2 Local astringents and local detergents	0.002	0.997	0.000
Y56.1 Antipruritics	0.002	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.997	0.000
Y58.9 Other and unspecified bacterial vaccines	0.002	0.997	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.997	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.997	0.000
Y58.5 Diphtheria vaccine	0.002	0.997	0.000
Y58.4 Tetanus vaccine	0.002	0.997	0.000
Y58.3 Plague vaccine	0.002	0.997	0.000
Y58.2 Cholera vaccine	0.002	0.997	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.997	0.000
Y58.0 BCG vaccine	0.002	0.997	0.000
Y59.9 Vaccine or biological substance, unspecified	0.002	0.997	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.997	0.000
Y59.3 Immunoglobulin	0.002	0.997	0.000
Y59.2 Protozoal vaccines	0.002	0.997	0.000
Y59.1 Rickettsial vaccines	0.002	0.997	0.000
Y59.0 Viral vaccines	0.002	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.002	0.997	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.997	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.997	0.000
Y42.4 Oral contraceptives	0.002	0.997	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.997	0.000
Y42.2 Antithyroid drugs	0.002	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.997	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.002	0.997	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.002	0.998	0.000
D37.4 Colon	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.002	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
Y51.0 Anticholinesterase agents	0.002	0.998	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.002	0.998	0.000
N15 Other renal tubulo-interstitial diseases	0.002	0.998	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.002	0.998	0.000
C15.5 Lower third of oesophagus	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
C16.0 Cardia	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.002	0.998	0.000
D45 Polycythaemia vera	0.002	0.998	0.000
C77.8 Lymph nodes of multiple regions	0.002	0.998	0.000
C77.4 Inguinal and lower limb lymph nodes	0.002	0.998	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.002	0.998	0.000
D48.1 Connective and other soft tissue	0.002	0.998	0.000
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Y40.8 Other systemic antibiotics	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
Y40.5 Aminoglycosides	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.3 Macrolides	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
C71 Malignant neoplasm of brain	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.002	0.998	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.002	0.998	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.002	0.998	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.002	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.002	0.998	0.000
C71.9 Brain, unspecified	0.002	0.998	0.000
D37.9 Digestive organ, unspecified	0.002	0.998	0.000
D37.7 Other digestive organs	0.002	0.998	0.000
D37.6 Liver, gallbladder and bile ducts	0.002	0.998	0.000
D37.2 Small intestine	0.002	0.998	0.000
D37.1 Stomach	0.002	0.998	0.000
D37.0 Lip, oral cavity and pharynx	0.002	0.998	0.000
C45 Mesothelioma	0.002	0.998	0.000
C77.9 Lymph node, unspecified	0.002	0.998	0.000
C77.3 Axillary and upper limb lymph nodes	0.002	0.998	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.002	0.998	0.000
D37.5 Rectum	0.002	0.998	0.000
D48.5 Skin	0.002	0.998	0.000
N18.9 Chronic renal failure, unspecified	0.002	0.998	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.002	0.998	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.002	0.998	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.002	0.998	0.000
I44.6 Other and unspecified fascicular block	0.002	0.998	0.000
G81.9 Hemiplegia, unspecified	0.002	0.998	0.000
O36.5 Maternal care for poor foetal growth	0.002	0.998	0.000
C71.2 Temporal lobe	0.002	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.002	0.998	0.000
D48.7 Other specified sites	0.002	0.998	0.000
D48.6 Breast	0.002	0.998	0.000
D48.4 Peritoneum	0.002	0.998	0.000
D48.3 Retroperitoneum	0.002	0.998	0.000
D48.2 Peripheral nerves and autonomic nervous system	0.002	0.998	0.000
D48.0 Bone and articular cartilage	0.002	0.998	0.000
Chapter II Neoplasms	0.002	0.998	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.002	0.998	0.000
N11.1 Chronic obstructive pyelonephritis	0.002	0.998	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.002	0.998	0.000
C80 Malignant neoplasm without specification of site	0.002	0.998	0.000
O36 Maternal care for other known or suspected foetal problems	0.002	0.998	0.000
I44 Atrioventricular and left bundle-branch block	0.002	0.998	0.000
C77.0 Lymph nodes of head, face and neck	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.002	0.998	0.000
D03 Melanoma in situ	0.002	0.998	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.002	0.998	0.000
C77.5 Intrapelvic lymph nodes	0.002	0.998	0.000
I44.2 Atrioventricular block, complete	0.002	0.998	0.000
C77.1 Intrathoracic lymph nodes	0.002	0.998	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.002	0.998	0.000
N14.3 Nephropathy induced by heavy metals	0.002	0.998	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.002	0.998	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.002	0.998	0.000
N14.0 Analgesic nephropathy	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.002	0.998	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.002	0.998	0.000
N15.1 Renal and perinephric abscess	0.002	0.998	0.000
N15.0 Balkan nephropathy	0.002	0.998	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.002	0.998	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.002	0.998	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.002	0.998	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.002	0.998	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.002	0.998	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.002	0.998	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
D39.1 Ovary	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
K01.1 Impacted teeth	0.000	0.998	0.002
C32 Malignant neoplasm of larynx	0.002	0.998	0.000
I44.0 Atrioventricular block, first degree	0.002	0.998	0.000
O36.8 Maternal care for other specified foetal problems	0.002	0.998	0.000
C71.1 Frontal lobe	0.002	0.998	0.000
M20.2 Hallux rigidus	0.002	0.998	0.000
Y40.0 Penicillins	0.002	0.998	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.002	0.998	0.000
D41.0 Kidney	0.002	0.998	0.000
M20 Acquired deformities of fingers and toes	0.002	0.998	0.000
D39.9 Female genital organ, unspecified	0.002	0.998	0.000
D39.7 Other female genital organs	0.002	0.998	0.000
D39.2 Placenta	0.002	0.998	0.000
D39.0 Uterus	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
C71.7 Brain stem	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
Z95.0 Presence of cardiac pacemaker	0.002	0.998	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
C32.9 Larynx, unspecified	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.002	0.998	0.000
D38.5 Other respiratory organs	0.002	0.998	0.000
D38.4 Thymus	0.002	0.998	0.000
D38.3 Mediastinum	0.002	0.998	0.000
D38.2 Pleura	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
D38.0 Larynx	0.002	0.998	0.000
D40.9 Male genital organ, unspecified	0.002	0.998	0.000
D40.7 Other male genital organs	0.002	0.998	0.000
D40.1 Testis	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
D42.9 Meninges, unspecified	0.002	0.998	0.000
D42.1 Spinal meninges	0.002	0.998	0.000
D42.0 Cerebral meninges	0.002	0.998	0.000
D43.9 Central nervous system, unspecified	0.002	0.998	0.000
D43.7 Other parts of central nervous system	0.002	0.998	0.000
D43.4 Spinal cord	0.002	0.998	0.000
D43.3 Cranial nerves	0.002	0.998	0.000
D43.2 Brain, unspecified	0.002	0.998	0.000
D43.1 Brain, infratentorial	0.002	0.998	0.000
D43.0 Brain, supratentorial	0.002	0.998	0.000
D44.9 Endocrine gland, unspecified	0.002	0.998	0.000
D44.8 Pluriglandular involvement	0.002	0.998	0.000
D44.7 Aortic body and other paraganglia	0.002	0.998	0.000
D44.6 Carotid body	0.002	0.998	0.000
D44.5 Pineal gland	0.002	0.998	0.000
D44.4 Craniopharyngeal duct	0.002	0.998	0.000
D44.3 Pituitary gland	0.002	0.998	0.000
D44.2 Parathyroid gland	0.002	0.998	0.000
D44.1 Adrenal gland	0.002	0.998	0.000
D44.0 Thyroid gland	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.002	0.998	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.002	0.998	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.002	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
D46.1 Refractory anaemia with sideroblasts	0.002	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.002	0.998	0.000
O36.9 Maternal care for foetal problem, unspecified	0.002	0.998	0.000
K51 Ulcerative colitis	0.000	0.998	0.002
Y95 Nosocomial condition	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.002	0.998	0.000
C45.2 Mesothelioma of pericardium	0.002	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.002	0.998	0.000
O36.6 Maternal care for excessive foetal growth	0.002	0.998	0.000
C32.0 Glottis	0.002	0.998	0.000
D00-D09 In situ neoplasms	0.002	0.998	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.002	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.002	0.998	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.002	0.998	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.002	0.998	0.000
C46 Kaposi's sarcoma	0.002	0.998	0.000
D41.9 Urinary organ, unspecified	0.002	0.998	0.000
D41.7 Other urinary organs	0.002	0.998	0.000
D41.3 Urethra	0.002	0.998	0.000
D41.2 Ureter	0.002	0.998	0.000
D41.1 Renal pelvis	0.002	0.998	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.002	0.998	0.000
C70 Malignant neoplasm of meninges	0.002	0.998	0.000
C69 Malignant neoplasm of eye and adnexa	0.002	0.998	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.002	0.998	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M20.0 Deformity of finger(s)	0.002	0.998	0.000
Chapter XX External causes of morbidity and mortality	0.002	0.998	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.002	0.998	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.002	0.998	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.002	0.998	0.000
O36.4 Maternal care for intra-uterine death	0.002	0.998	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations