TreeWAS – Variant ID: rs6902257

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
Chapter IX Diseases of the circulatory system	0.997	0.003
Chapter V Mental and behavioural disorders	0.989	0.011
I30-I52 Other forms of heart disease	0.986	0.014
Chapter IV Endocrine, nutritional and metabolic diseases	0.985	0.015
J40-J47 Chronic lower respiratory diseases	0.983	0.017
I50 Heart failure	0.961	0.039
J44 Other chronic obstructive pulmonary disease	0.961	0.039
Chapter VI Diseases of the nervous system	0.956	0.044
J90-J94 Other diseases of pleura	0.952	0.048
I70-I79 Diseases of arteries, arterioles and capillaries	0.952	0.048
F40-F48 Neurotic, stress-related and somatoform disorders	0.951	0.049
S40-S49 Injuries to the shoulder and upper arm	0.950	0.050
I95-I99 Other and unspecified disorders of the circulatory system	0.948	0.052
Chapter II Neoplasms	0.945	0.055
Chapter XIV Diseases of the genitourinary system	0.943	0.057
I44 Atrioventricular and left bundle-branch block	0.941	0.059
N17-N19 Renal failure	0.940	0.060
I50.0 Congestive heart failure	0.936	0.064
J43 Emphysema	0.935	0.065
J30-J39 Other diseases of upper respiratory tract	0.931	0.069
N17 Acute renal failure	0.930	0.070
F41 Other anxiety disorders	0.928	0.072
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.923	0.077
F30-F39 Mood [affective] disorders	0.921	0.079
N17.9 Acute renal failure, unspecified	0.920	0.080
T66-T78 Other and unspecified effects of external causes	0.916	0.084
Chapter I Certain infectious and parasitic diseases	0.913	0.087
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.909	0.091
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.909	0.091
E70-E90 Metabolic disorders	0.908	0.092
S90-S99 Injuries to the ankle and foot	0.907	0.093
N18 Chronic renal failure	0.906	0.094
G90-G99 Other disorders of the nervous system	0.905	0.095
J43.9 Emphysema, unspecified	0.901	0.099
N18.9 Chronic renal failure, unspecified	0.898	0.102
J33 Nasal polyp	0.891	0.109
N25-N29 Other disorders of kidney and ureter	0.890	0.110
G30-G32 Other degenerative diseases of the nervous system	0.889	0.111
F41.9 Anxiety disorder, unspecified	0.889	0.111
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.883	0.117
I95 Hypotension	0.882	0.118
I42 Cardiomyopathy	0.877	0.123
J32 Chronic sinusitis	0.875	0.125
G99 Other disorders of nervous system in diseases classified elsewhere	0.873	0.127
J00-J06 Acute upper respiratory infections	0.870	0.130
I74 Arterial embolism and thrombosis	0.870	0.130
J33.8 Other polyp of sinus	0.870	0.130
I05-I09 Chronic rheumatic heart diseases	0.868	0.132
E10-E14 Diabetes mellitus	0.861	0.139
S42 Fracture of shoulder and upper arm	0.860	0.140
J80-J84 Other respiratory diseases principally affecting the interstitium	0.860	0.140
J44.8 Other specified chronic obstructive pulmonary disease	0.858	0.142
S20-S29 Injuries to the thorax	0.857	0.143
N28 Other disorders of kidney and ureter, not elsewhere classified	0.856	0.144
T78 Adverse effects, not elsewhere classified	0.856	0.144
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.854	0.146
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.850	0.150
I77 Other disorders of arteries and arterioles	0.847	0.153
E20-E35 Disorders of other endocrine glands	0.845	0.155
E50-E64 Other nutritional deficiencies	0.845	0.155
N28.1 Cyst of kidney, acquired	0.843	0.157
J93 Pneumothorax	0.842	0.158
I38 Endocarditis, valve unspecified	0.841	0.159
F32 Depressive episode	0.839	0.161
S40 Superficial injury of shoulder and upper arm	0.837	0.163
I72 Other aneurysm	0.836	0.164
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.835	0.165
E83 Disorders of mineral metabolism	0.833	0.167
I44.0 Atrioventricular block, first degree	0.829	0.171
I31 Other diseases of pericardium	0.829	0.171
J32.9 Chronic sinusitis, unspecified	0.827	0.173
A30-A49 Other bacterial diseases	0.827	0.173
I95.1 Orthostatic hypotension	0.826	0.174
J90 Pleural effusion, not elsewhere classified	0.826	0.174
N20-N23 Urolithiasis	0.825	0.175
Chapter XXII Codes for special purposes	0.823	0.177
G99.2 Myelopathy in diseases classified elsewhere	0.822	0.178
F00-F09 Organic, including symptomatic, mental disorders	0.820	0.180
T78.2 Anaphylactic shock, unspecified	0.820	0.180
S32 Fracture of lumbar spine and pelvis	0.817	0.183
S42.2 Fracture of upper end of humerus	0.816	0.184
J09-J18 Influenza and pneumonia	0.812	0.188
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.810	0.190
I44.7 Left bundle-branch block, unspecified	0.808	0.192
G31.9 Degenerative disease of nervous system, unspecified	0.804	0.196
I98 Other disorders of circulatory system in diseases classified elsewhere	0.803	0.197
T36-T50 Poisoning by drugs, medicaments and biological substances	0.798	0.202
J47 Bronchiectasis	0.793	0.207
T92 Sequelae of injuries of upper limb	0.791	0.209
C51-C58 Malignant neoplasms of female genital organs	0.789	0.211
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.789	0.211
S42.20 Fracture of upper end of humerus (closed)	0.785	0.215
Chapter XX External causes of morbidity and mortality	0.782	0.218
J80 Adult respiratory distress syndrome	0.782	0.218
C60-C63 Malignant neoplasms of male genital organs	0.781	0.219
A00-A09 Intestinal infectious diseases	0.779	0.221
S70-S79 Injuries to the hip and thigh	0.777	0.223
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.777	0.223
N00-N08 Glomerular diseases	0.775	0.225
E83.4 Disorders of magnesium metabolism	0.775	0.225
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.775	0.225
B15-B19 Viral hepatitis	0.774	0.226
J91 Pleural effusion in conditions classified elsewhere	0.773	0.227
S10-S19 Injuries to the neck	0.772	0.228
A41 Other septicaemia	0.771	0.229
S50-S59 Injuries to the elbow and forearm	0.771	0.229
F32.2 Severe depressive episode without psychotic symptoms	0.769	0.231
S00-S09 Injuries to the head	0.768	0.232
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.767	0.233
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.767	0.233
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.766	0.234
S30 Superficial injury of abdomen, lower back and pelvis	0.764	0.235
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.764	0.236
I50.1 Left ventricular failure	0.763	0.237
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.762	0.238
E55 Vitamin D deficiency	0.762	0.238
E00-E07 Disorders of thyroid gland	0.758	0.242
J93.9 Pneumothorax, unspecified	0.758	0.242
I77.1 Stricture of artery	0.755	0.244
J02 Acute pharyngitis	0.755	0.245
I74.5 Embolism and thrombosis of iliac artery	0.755	0.245
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.753	0.247
N23 Unspecified renal colic	0.750	0.250
F33 Recurrent depressive disorder	0.747	0.253
J94 Other pleural conditions	0.746	0.254
F41.2 Mixed anxiety and depressive disorder	0.745	0.255
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.745	0.255
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.744	0.256
I42.0 Dilated cardiomyopathy	0.740	0.260
S90 Superficial injury of ankle and foot	0.739	0.261
I44.6 Other and unspecified fascicular block	0.739	0.261
S96 Injury of muscle and tendon at ankle and foot level	0.738	0.262
Q20-Q28 Congenital malformations of the circulatory system	0.738	0.262
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.737	0.263
S22 Fracture of rib(s), sternum and thoracic spine	0.737	0.263
N17.0 Acute renal failure with tubular necrosis	0.736	0.264
J30 Vasomotor and allergic rhinitis	0.733	0.267
Q60-Q64 Congenital malformations of the urinary system	0.732	0.268
A41.9 Septicaemia, unspecified	0.731	0.269
I37 Pulmonary valve disorders	0.730	0.270
J03 Acute tonsillitis	0.729	0.271
E14 Unspecified diabetes mellitus	0.729	0.271
G00-G09 Inflammatory diseases of the central nervous system	0.728	0.272
I05 Rheumatic mitral valve diseases	0.728	0.272
E40-E46 Malnutrition	0.725	0.275
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.722	0.278
S49 Other and unspecified injuries of shoulder and upper arm	0.722	0.278
E11 Non-insulin-dependent diabetes mellitus	0.722	0.278
S40.8 Other superficial injuries of shoulder and upper arm	0.721	0.279
F43 Reaction to severe stress, and adjustment disorders	0.721	0.279
S99 Other and unspecified injuries of ankle and foot	0.720	0.280
J37 Chronic laryngitis and laryngotracheitis	0.719	0.281
G91 Hydrocephalus	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.716	0.284
Q80-Q89 Other congenital malformations	0.716	0.284
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.716	0.284
I00-I02 Acute rheumatic fever	0.715	0.285
S80-S89 Injuries to the knee and lower leg	0.714	0.286
T88 Other complications of surgical and medical care, not elsewhere classified	0.714	0.286
T82.1 Mechanical complication of cardiac electronic device	0.713	0.287
B90-B94 Sequelae of infectious and parasitic diseases	0.712	0.288
B65-B83 Helminthiases	0.711	0.289
G50-G59 Nerve, nerve root and plexus disorders	0.711	0.289
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.709	0.291
F80-F89 Disorders of psychological development	0.709	0.291
F70-F79 Mental retardation	0.709	0.291
Q38-Q45 Other congenital malformations of the digestive system	0.708	0.292
J20-J22 Other acute lower respiratory infections	0.707	0.293
I52 Other heart disorders in diseases classified elsewhere	0.707	0.293
I48 Atrial fibrillation and flutter	0.707	0.293
I43 Cardiomyopathy in diseases classified elsewhere	0.707	0.293
I41 Myocarditis in diseases classified elsewhere	0.707	0.293
I40 Acute myocarditis	0.707	0.293
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.707	0.293
I36 Nonrheumatic tricuspid valve disorders	0.707	0.293
I33 Acute and subacute endocarditis	0.707	0.293
I32 Pericarditis in diseases classified elsewhere	0.707	0.293
E88 Other metabolic disorders	0.707	0.293
C01 Malignant neoplasm of base of tongue	0.707	0.293
T79-T79 Certain early complications of trauma	0.706	0.294
I30 Acute pericarditis	0.705	0.295
J41 Simple and mucopurulent chronic bronchitis	0.705	0.295
I44.1 Atrioventricular block, second degree	0.704	0.296
G70-G73 Diseases of myoneural junction and muscle	0.704	0.296
J42 Unspecified chronic bronchitis	0.704	0.296
E55.9 Vitamin D deficiency, unspecified	0.703	0.297
I44.3 Other and unspecified atrioventricular block	0.702	0.298
S01 Open wound of head	0.701	0.299
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.700	0.300
T92.1 Sequelae of fracture of arm	0.700	0.300
I98.2 Oesophageal varices in diseases classified elsewhere	0.700	0.300
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.697	0.303
E85 Amyloidosis	0.696	0.304
F60-F69 Disorders of adult personality and behaviour	0.695	0.305
I60-I69 Cerebrovascular diseases	0.694	0.306
C56 Malignant neoplasm of ovary	0.694	0.306
C02 Malignant neoplasm of other and unspecified parts of tongue	0.694	0.306
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.693	0.307
E27 Other disorders of adrenal gland	0.693	0.307
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.693	0.307
I50.9 Heart failure, unspecified	0.693	0.307
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.692	0.308
D37-D48 Neoplasms of uncertain or unknown behaviour	0.692	0.308
D00-D09 In situ neoplasms	0.690	0.310
J15 Bacterial pneumonia, not elsewhere classified	0.690	0.310
Chapter VIII Diseases of the ear and mastoid process	0.690	0.310
I08 Multiple valve diseases	0.689	0.311
S91 Open wound of ankle and foot	0.689	0.311
F31 Bipolar affective disorder	0.689	0.311
C43-C44 Melanoma and other malignant neoplasms of skin	0.688	0.312
F03 Unspecified dementia	0.688	0.312
N03 Chronic nephritic syndrome	0.688	0.312
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.687	0.313
J81 Pulmonary oedema	0.687	0.313
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.685	0.315
I44.2 Atrioventricular block, complete	0.685	0.315
E11.4 With neurological complications	0.685	0.315
I77.0 Arteriovenous fistula, acquired	0.684	0.316
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.683	0.317
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.682	0.318
I42.1 Obstructive hypertrophic cardiomyopathy	0.682	0.318
F48 Other neurotic disorders	0.682	0.318
F44 Dissociative [conversion] disorders	0.682	0.318
F42 Obsessive-compulsive disorder	0.682	0.318
E05 Thyrotoxicosis [hyperthyroidism]	0.682	0.318
S48 Traumatic amputation of shoulder and upper arm	0.681	0.319
S46 Injury of muscle and tendon at shoulder and upper arm level	0.681	0.319
S45 Injury of blood vessels at shoulder and upper arm level	0.681	0.319
S44 Injury of nerves at shoulder and upper arm level	0.681	0.319
S41 Open wound of shoulder and upper arm	0.681	0.319
S47 Crushing injury of shoulder and upper arm	0.681	0.319
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.681	0.319
S70 Superficial injury of hip and thigh	0.681	0.319
S32.3 Fracture of ilium	0.680	0.320
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.680	0.320
I99 Other and unspecified disorders of circulatory system	0.680	0.320
E23 Hypofunction and other disorders of pituitary gland	0.678	0.322
C40-C41 Malignant neoplasms of bone and articular cartilage	0.678	0.322
I31.3 Pericardial effusion (noninflammatory)	0.677	0.323
G40-G47 Episodic and paroxysmal disorders	0.677	0.323
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.677	0.323
F99-F99 Unspecified mental disorder	0.676	0.324
I42.8 Other cardiomyopathies	0.675	0.324
I46 Cardiac arrest	0.675	0.325
I44.5 Left posterior fascicular block	0.675	0.325
I44.4 Left anterior fascicular block	0.675	0.325
B99-B99 Other infectious diseases	0.674	0.326
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.674	0.326
I95.9 Hypotension, unspecified	0.674	0.326
J02.9 Acute pharyngitis, unspecified	0.673	0.327
E78.5 Hyperlipidaemia, unspecified	0.672	0.328
G80-G83 Cerebral palsy and other paralytic syndromes	0.671	0.329
J43.8 Other emphysema	0.670	0.329
J43.2 Centrilobular emphysema	0.670	0.329
J43.1 Panlobular emphysema	0.670	0.329
J43.0 MacLeod's syndrome	0.670	0.329
I72.4 Aneurysm of artery of lower extremity	0.669	0.331
I42.9 Cardiomyopathy, unspecified	0.667	0.333
N17.8 Other acute renal failure	0.667	0.333
N17.2 Acute renal failure with medullary necrosis	0.667	0.333
N17.1 Acute renal failure with acute cortical necrosis	0.667	0.333
F41.1 Generalised anxiety disorder	0.666	0.334
M05-M14 Inflammatory polyarthropathies	0.666	0.334
F41.8 Other specified anxiety disorders	0.665	0.335
F41.3 Other mixed anxiety disorders	0.665	0.335
G31.8 Other specified degenerative diseases of nervous system	0.664	0.336
I49 Other cardiac arrhythmias	0.664	0.336
G31.2 Degeneration of nervous system due to alcohol	0.664	0.336
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.663	0.337
J32.4 Chronic pansinusitis	0.662	0.337
T78.1 Other adverse food reactions, not elsewhere classified	0.661	0.339
E86 Volume depletion	0.661	0.339
S92 Fracture of foot, except ankle	0.661	0.339
Q00-Q07 Congenital malformations of the nervous system	0.661	0.339
S01.0 Open wound of scalp	0.661	0.339
F38 Other mood [affective] disorders	0.660	0.340
F34 Persistent mood [affective] disorders	0.660	0.340
F30 Manic episode	0.660	0.340
F39 Unspecified mood [affective] disorder	0.660	0.340
T98 Sequelae of other and unspecified effects of external causes	0.658	0.342
T75 Effects of other external causes	0.657	0.343
T74 Maltreatment syndromes	0.657	0.343
T73 Effects of other deprivation	0.657	0.343
T70 Effects of air pressure and water pressure	0.657	0.343
T69 Other effects of reduced temperature	0.657	0.343
T67 Effects of heat and light	0.657	0.343
T71 Asphyxiation	0.657	0.343
T68 Hypothermia	0.657	0.343
T66 Unspecified effects of radiation	0.657	0.343
C71 Malignant neoplasm of brain	0.656	0.344
T86 Failure and rejection of transplanted organs and tissues	0.656	0.344
M06 Other rheumatoid arthritis	0.656	0.344
I72.8 Aneurysm of other specified arteries	0.656	0.344
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.656	0.344
F40 Phobic anxiety disorders	0.656	0.344
C61 Malignant neoplasm of prostate	0.655	0.345
Q50-Q56 Congenital malformations of genital organs	0.655	0.345
B85-B89 Pediculosis, acariasis and other infestations	0.655	0.345
B50-B64 Protozoal diseases	0.655	0.345
B20-B24 Human immunodeficiency virus [HIV] disease	0.655	0.345
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.655	0.345
A75-A79 Rickettsioses	0.655	0.345
A70-A74 Other diseases caused by chlamydiae	0.655	0.345
A65-A69 Other spirochaetal diseases	0.655	0.345
A20-A28 Certain zoonotic bacterial diseases	0.655	0.345
A15-A19 Tuberculosis	0.655	0.345
E29 Testicular dysfunction	0.654	0.346
I31.9 Disease of pericardium, unspecified	0.654	0.346
J32.0 Chronic maxillary sinusitis	0.653	0.347
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.652	0.348
S37 Injury of urinary and pelvic organs	0.652	0.348
S36 Injury of intra-abdominal organs	0.652	0.348
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.652	0.348
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.652	0.348
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.652	0.348
S31 Open wound of abdomen, lower back and pelvis	0.652	0.348
C64-C68 Malignant neoplasms of urinary tract	0.652	0.348
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.652	0.348
M06.9 Rheumatoid arthritis, unspecified	0.652	0.348
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.651	0.348
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.651	0.348
Q35-Q37 Cleft lip and cleft palate	0.651	0.348
Q30-Q34 Congenital malformations of the respiratory system	0.651	0.348
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.651	0.348
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.651	0.348
S32.5 Fracture of pubis	0.651	0.349
E84 Cystic fibrosis	0.651	0.349
E79 Disorders of purine and pyrimidine metabolism	0.651	0.349
E77 Disorders of glycoprotein metabolism	0.651	0.349
E76 Disorders of glycosaminoglycan metabolism	0.651	0.349
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.651	0.349
E74 Other disorders of carbohydrate metabolism	0.651	0.349
E73 Lactose intolerance	0.651	0.349
E72 Other disorders of amino-acid metabolism	0.651	0.349
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.651	0.349
E70 Disorders of aromatic amino-acid metabolism	0.651	0.349
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.651	0.349
S98 Traumatic amputation of ankle and foot	0.651	0.349
S97 Crushing injury of ankle and foot	0.651	0.349
S95 Injury of blood vessels at ankle and foot level	0.651	0.349
S94 Injury of nerves at ankle and foot level	0.651	0.349
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.651	0.349
I72.3 Aneurysm of iliac artery	0.651	0.349
N18.8 Other chronic renal failure	0.650	0.350
N18.1 Chronic kidney disease, stage 1	0.650	0.350
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.649	0.351
F32.9 Depressive episode, unspecified	0.649	0.351
G96 Other disorders of central nervous system	0.649	0.351
G94 Other disorders of brain in diseases classified elsewhere	0.649	0.351
G90 Disorders of autonomic nervous system	0.649	0.351
G98 Other disorders of nervous system, not elsewhere classified	0.649	0.351
G92 Toxic encephalopathy	0.649	0.351
J14 Pneumonia due to Haemophilus influenzae	0.648	0.352
I78 Diseases of capillaries	0.648	0.352
S32.1 Fracture of sacrum	0.646	0.353
I07 Rheumatic tricuspid valve diseases	0.646	0.354
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.646	0.354
T93 Sequelae of injuries of lower limb	0.646	0.354
J46 Status asthmaticus	0.645	0.355
S20 Superficial injury of thorax	0.644	0.356
N10-N16 Renal tubulo-interstitial diseases	0.643	0.357
B18 Chronic viral hepatitis	0.642	0.358
E14.9 Without complications	0.642	0.358
C49 Malignant neoplasm of other connective and soft tissue	0.641	0.359
F32.3 Severe depressive episode with psychotic symptoms	0.641	0.359
J06 Acute upper respiratory infections of multiple and unspecified sites	0.640	0.360
C97 Malignant neoplasms of independent (primary) multiple sites	0.639	0.361
J33.1 Polypoid sinus degeneration	0.638	0.361
S22.3 Fracture of rib	0.638	0.362
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.638	0.362
N27 Small kidney of unknown cause	0.638	0.362
N25 Disorders resulting from impaired renal tubular function	0.638	0.362
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.637	0.362
I72.0 Aneurysm of carotid artery	0.637	0.363
S27 Injury of other and unspecified intrathoracic organs	0.637	0.363
X60-X84 Intentional self-harm	0.637	0.363
B35-B49 Mycoses	0.637	0.363
S42.0 Fracture of clavicle	0.637	0.363
E83.3 Disorders of phosphorus metabolism	0.636	0.364
T46 Poisoning by agents primarily affecting the cardiovascular system	0.634	0.365
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.633	0.366
E05.9 Thyrotoxicosis, unspecified	0.633	0.367
T95 Sequelae of burns, corrosions and frostbite	0.633	0.367
T94 Sequelae of injuries involving multiple and unspecified body regions	0.633	0.367
T91 Sequelae of injuries of neck and trunk	0.633	0.367
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.633	0.367
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.633	0.367
I95.8 Other hypotension	0.633	0.367
I95.0 Idiopathic hypotension	0.633	0.367
I95.2 Hypotension due to drugs	0.632	0.368
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.632	0.368
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.631	0.369
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.631	0.369
J93.8 Other pneumothorax	0.630	0.369
A80-A89 Viral infections of the central nervous system	0.630	0.370
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.630	0.370
T87 Complications peculiar to reattachment and amputation	0.630	0.370
I71 Aortic aneurysm and dissection	0.629	0.371
E22 Hyperfunction of pituitary gland	0.629	0.371
T92.9 Sequelae of unspecified injury of upper limb	0.629	0.371
I42.7 Cardiomyopathy due to drugs and other external agents	0.628	0.371
I42.6 Alcoholic cardiomyopathy	0.628	0.371
I42.5 Other restrictive cardiomyopathy	0.628	0.371
I42.4 Endocardial fibroelastosis	0.628	0.371
I42.3 Endomyocardial (eosinophilic) disease	0.628	0.371
J03.9 Acute tonsillitis, unspecified	0.628	0.372
I05.0 Mitral stenosis	0.628	0.372
S32.4 Fracture of acetabulum	0.628	0.372
J32.8 Other chronic sinusitis	0.627	0.373
J32.3 Chronic sphenoidal sinusitis	0.627	0.373
J32.1 Chronic frontal sinusitis	0.627	0.373
F45 Somatoform disorders	0.626	0.374
N18.4 Chronic kidney disease, stage 4	0.626	0.374
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.626	0.374
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.626	0.374
N03.9 Unspecified	0.626	0.374
S40.0 Contusion of shoulder and upper arm	0.626	0.374
C50-C50 Malignant neoplasm of breast	0.625	0.375
I35 Nonrheumatic aortic valve disorders	0.625	0.375
I77.8 Other specified disorders of arteries and arterioles	0.624	0.376
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.624	0.376
J01 Acute sinusitis	0.624	0.376
I74.9 Embolism and thrombosis of unspecified artery	0.624	0.376
I74.8 Embolism and thrombosis of other arteries	0.624	0.376
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.624	0.376
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.624	0.376
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.624	0.376
I74.0 Embolism and thrombosis of abdominal aorta	0.624	0.376
G93 Other disorders of brain	0.623	0.377
I09 Other rheumatic heart diseases	0.622	0.377
I06 Rheumatic aortic valve diseases	0.622	0.377
S51 Open wound of forearm	0.622	0.378
T80 Complications following infusion, transfusion and therapeutic injection	0.621	0.378
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.620	0.380
C90 Multiple myeloma and malignant plasma cell neoplasms	0.620	0.380
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.619	0.381
N26 Unspecified contracted kidney	0.619	0.381
S90.9 Superficial injury of ankle and foot, unspecified	0.619	0.381
E13 Other specified diabetes mellitus	0.618	0.382
T90 Sequelae of injuries of head	0.618	0.382
E12 Malnutrition-related diabetes mellitus	0.617	0.382
S42.9 Fracture of shoulder girdle, part unspecified	0.617	0.383
S42.8 Fracture of other parts of shoulder and upper arm	0.617	0.383
S42.7 Multiple fractures of clavicle, scapula and humerus	0.617	0.383
J82 Pulmonary eosinophilia, not elsewhere classified	0.616	0.383
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.616	0.383
I70 Atherosclerosis	0.615	0.384
C09 Malignant neoplasm of tonsil	0.615	0.385
G40 Epilepsy	0.615	0.385
N18.5 Chronic kidney disease, stage 5	0.615	0.385
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.614	0.386
S26 Injury of heart	0.614	0.386
S25 Injury of blood vessels of thorax	0.614	0.386
S24 Injury of nerves and spinal cord at thorax level	0.614	0.386
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.614	0.386
S21 Open wound of thorax	0.614	0.386
A08 Viral and other specified intestinal infections	0.614	0.386
N18.0 End-stage renal disease	0.614	0.386
N28.0 Ischaemia and infarction of kidney	0.613	0.386
T78.9 Adverse effect, unspecified	0.613	0.386
T78.8 Other adverse effects, not elsewhere classified	0.613	0.386
T78.0 Anaphylactic shock due to adverse food reaction	0.613	0.386
E83.5 Disorders of calcium metabolism	0.613	0.386
E78.9 Disorder of lipoprotein metabolism, unspecified	0.613	0.387
C13 Malignant neoplasm of hypopharynx	0.613	0.387
C11 Malignant neoplasm of nasopharynx	0.613	0.387
C10 Malignant neoplasm of oropharynx	0.613	0.387
C08 Malignant neoplasm of other and unspecified major salivary glands	0.613	0.387
C06 Malignant neoplasm of other and unspecified parts of mouth	0.613	0.387
C05 Malignant neoplasm of palate	0.613	0.387
C04 Malignant neoplasm of floor of mouth	0.613	0.387
C03 Malignant neoplasm of gum	0.613	0.387
C00 Malignant neoplasm of lip	0.613	0.387
C12 Malignant neoplasm of pyriform sinus	0.613	0.387
C07 Malignant neoplasm of parotid gland	0.613	0.387
F33.9 Recurrent depressive disorder, unspecified	0.612	0.388
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.611	0.389
G31.1 Senile degeneration of brain, not elsewhere classified	0.609	0.390
G31.0 Circumscribed brain atrophy	0.609	0.390
I42.2 Other hypertrophic cardiomyopathy	0.609	0.390
B16 Acute hepatitis B	0.609	0.390
T15-T19 Effects of foreign body entering through natural orifice	0.609	0.391
C48.2 Peritoneum, unspecified	0.608	0.392
X20-X29 Contact with venomous animals and plants	0.608	0.392
I77.5 Necrosis of artery	0.607	0.393
I77.4 Coeliac artery compression syndrome	0.607	0.393
I77.3 Arterial fibromuscular dysplasia	0.607	0.393
I77.2 Rupture of artery	0.607	0.393
A50-A64 Infections with a predominantly sexual mode of transmission	0.606	0.393
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.606	0.394
E35 Disorders of endocrine glands in diseases classified elsewhere	0.606	0.394
E34 Other endocrine disorders	0.606	0.394

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations