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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs6921919
log Bayes Factor = 92.1777
Chromosome 6   position 28,325,201  (GRCh37) Explore rs6921919 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
E83.1 Disorders of iron metabolism
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.998 0.002 0.000
E10.9 Without complications
0.998 0.002 0.000
C15-C26 Malignant neoplasms of digestive organs
0.998 0.002 0.000
C25 Malignant neoplasm of pancreas
0.994 0.006 0.000
R31 Unspecified haematuria
0.000 0.006 0.994
E20-E35 Disorders of other endocrine glands
0.993 0.007 0.000
Chapter II Neoplasms
0.992 0.008 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.990 0.010 0.000
C25.9 Pancreas, unspecified
0.983 0.017 0.000
E27 Other disorders of adrenal gland
0.983 0.017 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.982 0.018 0.000
D00-D09 In situ neoplasms
0.977 0.023 0.000
E27.1 Primary adrenocortical insufficiency
0.975 0.025 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.974 0.026 0.000
E14 Unspecified diabetes mellitus
0.966 0.034 0.000
C15 Malignant neoplasm of oesophagus
0.951 0.049 0.000
D03 Melanoma in situ
0.950 0.050 0.000
E14.3 With ophthalmic complications
0.942 0.058 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.935 0.065 0.000
E13 Other specified diabetes mellitus
0.934 0.066 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.069 0.931
C04 Malignant neoplasm of floor of mouth
0.925 0.075 0.000
D03.5 Melanoma in situ of trunk
0.923 0.077 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.922 0.078 0.000
E10.3 With ophthalmic complications
0.920 0.080 0.000
D04 Carcinoma in situ of skin
0.902 0.098 0.000
C03 Malignant neoplasm of gum
0.899 0.101 0.000
C25.0 Head of pancreas
0.897 0.103 0.000
E10.1 With ketoacidosis
0.895 0.105 0.000
E10.2 With renal complications
0.895 0.105 0.000
C15.9 Oesophagus, unspecified
0.891 0.109 0.000
E10.4 With neurological complications
0.891 0.109 0.000
K51 Ulcerative colitis
0.000 0.115 0.885
C02 Malignant neoplasm of other and unspecified parts of tongue
0.883 0.117 0.000
C22.1 Intrahepatic bile duct carcinoma
0.882 0.118 0.000
E13.9 Without complications
0.882 0.118 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.880 0.120 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.855 0.145 0.000
D06 Carcinoma in situ of cervix uteri
0.851 0.149 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.850 0.150 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.155 0.845
C04.9 Floor of mouth, unspecified
0.844 0.156 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.839 0.161 0.000
C16 Malignant neoplasm of stomach
0.838 0.162 0.000
C13 Malignant neoplasm of hypopharynx
0.838 0.162 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.832 0.168 0.000
E29 Testicular dysfunction
0.830 0.170 0.000
E34 Other endocrine disorders
0.830 0.170 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.828 0.172 0.000
K51.4 Pseudopolyposis of colon
0.000 0.175 0.825
C07 Malignant neoplasm of parotid gland
0.820 0.180 0.000
C02.9 Tongue, unspecified
0.816 0.184 0.000
C15.4 Middle third of oesophagus
0.812 0.188 0.000
E20 Hypoparathyroidism
0.809 0.191 0.000
C25.3 Pancreatic duct
0.809 0.191 0.000
E83 Disorders of mineral metabolism
0.002 0.192 0.806
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.806 0.194 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.800 0.200 0.000
E05.8 Other thyrotoxicosis
0.797 0.202 0.000
C45 Mesothelioma
0.797 0.203 0.000
C43 Malignant melanoma of skin
0.796 0.204 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.795 0.205 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.208 0.792
D04.2 Skin of ear and external auricular canal
0.782 0.218 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.780 0.220 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.778 0.222 0.000
E10.5 With peripheral circulatory complications
0.775 0.225 0.000
C04.0 Anterior floor of mouth
0.775 0.225 0.000
C03.1 Lower gum
0.773 0.227 0.000
D04.6 Skin of upper limb, including shoulder
0.772 0.228 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.228 0.772
E31 Polyglandular dysfunction
0.770 0.229 0.000
C22.9 Liver, unspecified
0.770 0.230 0.000
C03.9 Gum, unspecified
0.768 0.232 0.000
C05 Malignant neoplasm of palate
0.766 0.234 0.000
E14.5 With peripheral circulatory complications
0.765 0.235 0.000
D06.9 Cervix, unspecified
0.765 0.235 0.000
C16.5 Lesser curvature of stomach, unspecified
0.762 0.238 0.000
E40-E46 Malnutrition
0.761 0.239 0.000
E25 Adrenogenital disorders
0.760 0.240 0.000
E34.9 Endocrine disorder, unspecified
0.759 0.241 0.000
C49.0 Connective and soft tissue of head, face and neck
0.753 0.247 0.000
C23 Malignant neoplasm of gallbladder
0.751 0.248 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.751 0.249 0.000
E10.7 With multiple complications
0.750 0.250 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.750 0.250 0.000
C01 Malignant neoplasm of base of tongue
0.744 0.256 0.000
E14.4 With neurological complications
0.744 0.256 0.000
C11 Malignant neoplasm of nasopharynx
0.744 0.256 0.000
C32 Malignant neoplasm of larynx
0.737 0.263 0.000
D03.2 Melanoma in situ of ear and external auricular canal
0.735 0.265 0.000
C25.4 Endocrine pancreas
0.735 0.265 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.734 0.266 0.000
E10.0 With coma
0.733 0.267 0.000
E27.9 Disorder of adrenal gland, unspecified
0.733 0.267 0.000
C10 Malignant neoplasm of oropharynx
0.732 0.268 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.731 0.269 0.000
C25.7 Other parts of pancreas
0.730 0.270 0.000
E27.2 Addisonian crisis
0.730 0.270 0.000
E16.1 Other hypoglycaemia
0.728 0.272 0.000
E03.1 Congenital hypothyroidism without goitre
0.727 0.273 0.000
C09 Malignant neoplasm of tonsil
0.726 0.274 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.724 0.276 0.000
E14.6 With other specified complications
0.721 0.279 0.000
D04.7 Skin of lower limb, including hip
0.718 0.282 0.000
C49.3 Connective and soft tissue of thorax
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
C15.0 Cervical part of oesophagus
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
C25.2 Tail of pancreas
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.284 0.000
E16.3 Increased secretion of glucagon
0.716 0.284 0.000
C15.1 Thoracic part of oesophagus
0.716 0.284 0.000
C25.1 Body of pancreas
0.716 0.284 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.715 0.285 0.000
D03.1 Melanoma in situ of eyelid, including canthus
0.714 0.286 0.000
E29.1 Testicular hypofunction
0.714 0.286 0.000
E24 Cushing's syndrome
0.714 0.286 0.000
C25.8 Overlapping lesion of pancreas
0.713 0.287 0.000
D03.4 Melanoma in situ of scalp and neck
0.713 0.287 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.712 0.288 0.000
E32 Diseases of thymus
0.712 0.288 0.000
E30 Disorders of puberty, not elsewhere classified
0.712 0.288 0.000
D04.5 Skin of trunk
0.712 0.288 0.000
E23 Hypofunction and other disorders of pituitary gland
0.709 0.291 0.000
C06.0 Cheek mucosa
0.707 0.293 0.000
C18 Malignant neoplasm of colon
0.706 0.294 0.000
E27.5 Adrenomedullary hyperfunction
0.704 0.295 0.000
E27.0 Other adrenocortical overactivity
0.704 0.295 0.000
C45.9 Mesothelioma, unspecified
0.705 0.295 0.000
C12 Malignant neoplasm of pyriform sinus
0.704 0.296 0.000
E21.3 Hyperparathyroidism, unspecified
0.704 0.296 0.000
C18.9 Colon, unspecified
0.702 0.298 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.701 0.299 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.700 0.299 0.000
D03.8 Melanoma in situ of other sites
0.699 0.301 0.000
E10.6 With other specified complications
0.696 0.304 0.000
E14.1 With ketoacidosis
0.694 0.306 0.000
E13.3 With ophthalmic complications
0.693 0.306 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.693 0.307 0.000
E14.7 With multiple complications
0.692 0.308 0.000
E14.0 With coma
0.692 0.308 0.000
C13.9 Hypopharynx, unspecified
0.690 0.310 0.000
C71 Malignant neoplasm of brain
0.689 0.310 0.000
C43.4 Malignant melanoma of scalp and neck
0.688 0.312 0.000
C43.9 Malignant melanoma of skin, unspecified
0.687 0.313 0.000
E14.2 Withrenal complications
0.684 0.316 0.000
C15.8 Overlapping lesion of oesophagus
0.682 0.318 0.000
C15.2 Abdominal part of oesophagus
0.682 0.318 0.000
C71.1 Frontal lobe
0.682 0.318 0.000
D03.9 Melanoma in situ, unspecified
0.681 0.319 0.000
D03.0 Melanoma in situ of lip
0.681 0.319 0.000
C24.0 Extrahepatic bile duct
0.678 0.322 0.000
C51-C58 Malignant neoplasms of female genital organs
0.678 0.322 0.000
E20.9 Hypoparathyroidism, unspecified
0.677 0.323 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.676 0.324 0.000
C32.1 Supraglottis
0.671 0.329 0.000
C22.7 Other specified carcinomas of liver
0.670 0.330 0.000
C22.4 Other sarcomas of liver
0.670 0.330 0.000
C22.3 Angiosarcoma of liver
0.670 0.330 0.000
C22.2 Hepatoblastoma
0.670 0.330 0.000
E13.8 With unspecified complications
0.669 0.330 0.000
E13.7 With multiple complications
0.669 0.330 0.000
E13.6 With other specified complications
0.669 0.330 0.000
E13.5 With peripheral circulatory complications
0.669 0.330 0.000
E13.4 With neurological complications
0.669 0.330 0.000
E13.2 With renal complications
0.669 0.330 0.000
E13.1 With ketoacidosis
0.669 0.330 0.000
E13.0 With coma
0.669 0.330 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.668 0.331 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.667 0.333 0.000
C16.8 Overlapping lesion of stomach
0.665 0.335 0.000
C49.9 Connective and soft tissue, unspecified
0.665 0.335 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.336 0.664
C43.5 Malignant melanoma of trunk
0.664 0.336 0.000
C04.8 Overlapping lesion of floor of mouth
0.663 0.337 0.000
C04.1 Lateral floor of mouth
0.663 0.337 0.000
D04.3 Skin of other and unspecified parts of face
0.663 0.337 0.000
D09 Carcinoma in situ of other and unspecified sites
0.662 0.338 0.000
C13.0 Postcricoid region
0.661 0.339 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.661 0.339 0.000
C46 Kaposi's sarcoma
0.661 0.339 0.000
D04.9 Skin, unspecified
0.661 0.339 0.000
C00 Malignant neoplasm of lip
0.661 0.339 0.000
C15.3 Upper third of oesophagus
0.659 0.341 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.652 0.348 0.000
C05.9 Palate, unspecified
0.647 0.353 0.000
D04.8 Skin of other sites
0.647 0.353 0.000
D04.0 Skin of lip
0.647 0.353 0.000
C38.4 Pleura
0.646 0.354 0.000
C03.0 Upper gum
0.645 0.355 0.000
C16.0 Cardia
0.642 0.358 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.642 0.358 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.359 0.640
C45.0 Mesothelioma of pleura
0.638 0.362 0.000
C02.2 Ventral surface of tongue
0.637 0.362 0.000
C24.9 Biliary tract, unspecified
0.633 0.367 0.000
C02.8 Overlapping lesion of tongue
0.633 0.367 0.000
C02.3 Anterior two-thirds of tongue, part unspecified
0.633 0.367 0.000
C02.0 Dorsal surface of tongue
0.633 0.367 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.632 0.368 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.625 0.374 0.000
C02.4 Lingual tonsil
0.621 0.378 0.000
E14.9 Without complications
0.617 0.383 0.000
E07 Other disorders of thyroid
0.615 0.385 0.000
C70 Malignant neoplasm of meninges
0.614 0.386 0.000
C06.2 Retromolar area
0.613 0.387 0.000
C08.9 Major salivary gland, unspecified
0.612 0.388 0.000
E31.0 Autoimmune polyglandular failure
0.611 0.389 0.000
D06.7 Other parts of cervix
0.610 0.390 0.000
D06.1 Exocervix
0.610 0.390 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.610 0.390 0.000
C31 Malignant neoplasm of accessory sinuses
0.610 0.390 0.000
C37 Malignant neoplasm of thymus
0.610 0.390 0.000
C33 Malignant neoplasm of trachea
0.610 0.390 0.000
C49.6 Connective and soft tissue of trunk, unspecified
0.607 0.393 0.000
E83.4 Disorders of magnesium metabolism
0.001 0.393 0.606
C17 Malignant neoplasm of small intestine
0.605 0.395 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.603 0.397 0.000
E10.8 With unspecified complications
0.602 0.398 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.602 0.398 0.000
C49.8 Overlapping lesion of connective and soft tissue
0.602 0.398 0.000
C49.4 Connective and soft tissue of abdomen
0.602 0.398 0.000
C16.4 Pylorus
0.601 0.399 0.000
C13.8 Overlapping lesion of hypopharynx
0.600 0.399 0.000
C13.2 Posterior wall of hypopharynx
0.600 0.399 0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect
0.600 0.399 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.600 0.400 0.000
C02.1 Border of tongue
0.600 0.400 0.000
C15.5 Lower third of oesophagus
0.597 0.403 0.000
D06.0 Endocervix
0.597 0.403 0.000
E29.9 Testicular dysfunction, unspecified
0.595 0.405 0.000
E29.8 Other testicular dysfunction
0.595 0.405 0.000
E29.0 Testicular hyperfunction
0.595 0.405 0.000
K51.5 Mucosal proctocolitis
0.000 0.405 0.595
E34.5 Androgen resistance syndrome
0.595 0.405 0.000
E34.4 Constitutional tall stature
0.595 0.405 0.000
E34.3 Short stature, not elsewhere classified
0.595 0.405 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.595 0.405 0.000
E34.1 Other hypersecretion of intestinal hormones
0.595 0.405 0.000
C16.6 Greater curvature of stomach, unspecified
0.595 0.405 0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth
0.594 0.406 0.000
C06.1 Vestibule of mouth
0.594 0.406 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.593 0.407 0.000
E46 Unspecified protein-energy malnutrition
0.590 0.410 0.000
D04.1 Skin of eyelid, including canthus
0.588 0.412 0.000
C18.6 Descending colon
0.585 0.415 0.000
C49.1 Connective and soft tissue of upper limb, including shoulder
0.583 0.417 0.000
E28 Ovarian dysfunction
0.583 0.417 0.000
C06.9 Mouth, unspecified
0.582 0.418 0.000
E20.8 Other hypoparathyroidism
0.580 0.420 0.000
E20.1 Pseudohypoparathyroidism
0.580 0.420 0.000
E20.0 Idiopathic hypoparathyroidism
0.580 0.420 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.002 0.421 0.578
E83.8 Other disorders of mineral metabolism
0.002 0.421 0.578
E83.2 Disorders of zinc metabolism
0.002 0.421 0.578
E83.0 Disorders of copper metabolism
0.002 0.421 0.578
C20 Malignant neoplasm of rectum
0.578 0.422 0.000
C16.9 Stomach, unspecified
0.577 0.423 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.577 0.423 0.000
C08.0 Submandibular gland
0.575 0.425 0.000
C22.0 Liver cell carcinoma
0.573 0.427 0.000
E03.8 Other specified hypothyroidism
0.572 0.428 0.000
C45.2 Mesothelioma of pericardium
0.571 0.429 0.000
C45.1 Mesothelioma of peritoneum
0.571 0.429 0.000
C43.8 Overlapping malignant melanoma of skin
0.570 0.429 0.000
C43.0 Malignant melanoma of lip
0.570 0.429 0.000
C24.8 Overlapping lesion of biliary tract
0.570 0.430 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.570 0.430 0.000
E24.2 Drug-induced Cushing's syndrome
0.570 0.430 0.000
C11.9 Nasopharynx, unspecified
0.567 0.433 0.000
E14.8 With unspecified complications
0.564 0.435 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.565 0.435 0.000
E26 Hyperaldosteronism
0.563 0.436 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.560 0.440 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.559 0.441 0.000
E21.4 Other specified disorders of parathyroid gland
0.559 0.441 0.000
E21.2 Other hyperparathyroidism
0.559 0.441 0.000
C08.8 Overlapping lesion of major salivary glands
0.558 0.442 0.000
C08.1 Sublingual gland
0.558 0.442 0.000
C69 Malignant neoplasm of eye and adnexa
0.555 0.445 0.000
E24.0 Pituitary-dependent Cushing's disease
0.553 0.447 0.000
E31.9 Polyglandular dysfunction, unspecified
0.552 0.447 0.000
E31.8 Other polyglandular dysfunction
0.552 0.447 0.000
E31.1 Polyglandular hyperfunction
0.552 0.447 0.000
C32.9 Larynx, unspecified
0.552 0.448 0.000
E34.0 Carcinoid syndrome
0.550 0.450 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.550 0.450 0.000
C05.8 Overlapping lesion of palate
0.549 0.450 0.000
C05.2 Uvula
0.549 0.450 0.000
C05.0 Hard palate
0.549 0.450 0.000
C10.9 Oropharynx, unspecified
0.546 0.454 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.546 0.454 0.000
E45 Retarded development following protein-energy malnutrition
0.546 0.454 0.000
E43 Unspecified severe protein-energy malnutrition
0.546 0.454 0.000
E42 Marasmic kwashiorkor
0.546 0.454 0.000
E41 Nutritional marasmus
0.546 0.454 0.000
E40 Kwashiorkor
0.546 0.454 0.000
E25.9 Adrenogenital disorder, unspecified
0.545 0.455 0.000
E25.8 Other adrenogenital disorders
0.545 0.455 0.000
D07.1 Vulva
0.540 0.460 0.000
E23.7 Disorder of pituitary gland, unspecified
0.540 0.460 0.000
C53 Malignant neoplasm of cervix uteri
0.538 0.461 0.000
C30.0 Nasal cavity
0.538 0.462 0.000
C09.9 Tonsil, unspecified
0.537 0.463 0.000
K90 Intestinal malabsorption
0.537 0.463 0.000
C16.1 Fundus of stomach
0.533 0.466 0.000
C11.8 Overlapping lesion of nasopharynx
0.533 0.467 0.000
C11.3 Anterior wall of nasopharynx
0.533 0.467 0.000
C11.2 Lateral wall of nasopharynx
0.533 0.467 0.000
C11.1 Posterior wall of nasopharynx
0.533 0.467 0.000
C11.0 Superior wall of nasopharynx
0.533 0.467 0.000
C84.0 Mycosis fungoides
0.533 0.467 0.000
C49.5 Connective and soft tissue of pelvis
0.533 0.467 0.000
E23.6 Other disorders of pituitary gland
0.533 0.467 0.000
C16.3 Pyloric antrum
0.531 0.469 0.000
C32.8 Overlapping lesion of larynx
0.528 0.472 0.000
C32.3 Laryngeal cartilage
0.528 0.472 0.000
C32.2 Subglottis
0.528 0.472 0.000
D02.0 Larynx
0.528 0.472 0.000
C16.2 Body of stomach
0.526 0.473 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.525 0.474 0.000
C10.8 Overlapping lesion of oropharynx
0.524 0.475 0.000
C10.4 Branchial cleft
0.524 0.475 0.000
C10.3 Posterior wall of oropharynx
0.524 0.475 0.000
C10.2 Lateral wall of oropharynx
0.524 0.475 0.000
C10.1 Anterior surface of epiglottis
0.524 0.475 0.000
C10.0 Vallecula
0.524 0.475 0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura
0.524 0.475 0.000
C38.3 Mediastinum, part unspecified
0.524 0.475 0.000
C38.2 Posterior mediastinum
0.524 0.475 0.000
C38.1 Anterior mediastinum
0.524 0.475 0.000
C38.0 Heart
0.524 0.475 0.000
D04.4 Skin of scalp and neck
0.524 0.476 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.523 0.476 0.000
C09.8 Overlapping lesion of tonsil
0.521 0.479 0.000
C09.1 Tonsillar pillar (anterior) (posterior)
0.521 0.479 0.000
C09.0 Tonsillar fossa
0.521 0.479 0.000
D01.2 Rectum
0.520 0.480 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.518 0.482 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.517 0.483 0.000
E06 Thyroiditis
0.516 0.483 0.000
C17.0 Duodenum
0.516 0.484 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
C71.4 Occipital lobe
0.513 0.486 0.000
D02.4 Respiratory system, unspecified
0.513 0.487 0.000
D02.3 Other parts of respiratory system
0.513 0.487 0.000
D02.2 Bronchus and lung
0.513 0.487 0.000
D02.1 Trachea
0.513 0.487 0.000
D00.1 Oesophagus
0.512 0.488 0.000
E24.8 Other Cushing's syndrome
0.512 0.488 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.512 0.488 0.000
E24.3 Ectopic ACTH syndrome
0.512 0.488 0.000
E24.1 Nelson's syndrome
0.512 0.488 0.000
E30.9 Disorder of puberty, unspecified
0.510 0.489 0.000
E30.8 Other disorders of puberty
0.510 0.489 0.000
E30.1 Precocious puberty
0.510 0.489 0.000
E30.0 Delayed puberty
0.510 0.489 0.000
E32.9 Disease of thymus, unspecified
0.510 0.489 0.000
E32.8 Other diseases of thymus
0.510 0.489 0.000
E32.1 Abscess of thymus
0.510 0.489 0.000
E32.0 Persistent hyperplasia of thymus
0.510 0.489 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.510 0.489 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.510 0.489 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.510 0.489 0.000
C18.4 Transverse colon
0.510 0.490 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.508 0.492 0.000
E23.1 Drug-induced hypopituitarism
0.508 0.492 0.000
E34.8 Other specified endocrine disorders
0.506 0.494 0.000
C18.1 Appendix
0.505 0.495 0.000
C40 Malignant neoplasm of bone and articular cartilage of limbs
0.504 0.495 0.000
D01.0 Colon
0.504 0.496 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.503 0.497 0.000
C71.0 Cerebrum, except lobes and ventricles
0.503 0.497 0.000
D01.9 Digestive organ, unspecified
0.503 0.497 0.000
D01.7 Other specified digestive organs
0.503 0.497 0.000
D01.5 Liver, gallbladder and bile ducts
0.503 0.497 0.000
D01.4 Other and unspecified parts of intestine
0.503 0.497 0.000
D01.1 Rectosigmoid junction
0.503 0.497 0.000
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)
0.502 0.498 0.000
C85.1 B-cell lymphoma, unspecified
0.498 0.502 0.000
D00.2 Stomach
0.497 0.503 0.000
C95 Leukaemia of unspecified cell type
0.495 0.505 0.000
C71.7 Brain stem
0.494 0.505 0.000
C71.6 Cerebellum
0.494 0.505 0.000
C71.5 Cerebral ventricle
0.494 0.505 0.000
C84.5 Other and unspecified T-cell lymphomas
0.492 0.508 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.489 0.510 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.489 0.511 0.000
C58 Malignant neoplasm of placenta
0.486 0.514 0.000
C74 Malignant neoplasm of adrenal gland
0.485 0.514 0.000
C53.9 Cervix uteri, unspecified
0.485 0.515 0.000
C51 Malignant neoplasm of vulva
0.485 0.515 0.000
E23.2 Diabetes insipidus
0.485 0.515 0.000
C71.8 Overlapping lesion of brain
0.483 0.516 0.000
D07.4 Penis
0.483 0.517 0.000
D01.3 Anus and anal canal
0.483 0.517 0.000
C45.7 Mesothelioma of other sites
0.482 0.517 0.000
C30.1 Middle ear
0.479 0.521 0.000
C78.0 Secondary malignant neoplasm of lung
0.477 0.523 0.000
E50-E64 Other nutritional deficiencies
0.477 0.523 0.000
C70.0 Cerebral meninges
0.476 0.524 0.000
E07.8 Other specified disorders of thyroid
0.475 0.525 0.000
C18.8 Overlapping lesion of colon
0.475 0.525 0.000
D09.9 Carcinoma in situ, unspecified
0.474 0.525 0.000
D09.7 Carcinoma in situ of other specified sites
0.474 0.525 0.000
D09.3 Thyroid and other endocrine glands
0.474 0.525 0.000
D09.2 Eye
0.474 0.525 0.000
D09.1 Other and unspecified urinary organs
0.474 0.525 0.000
C46.9 Kaposi's sarcoma, unspecified
0.474 0.526 0.000
C46.8 Kaposi's sarcoma of multiple organs
0.474 0.526 0.000
C46.7 Kaposi's sarcoma of other sites
0.474 0.526 0.000
C46.3 Kaposi's sarcoma of lymph nodes
0.474 0.526 0.000
C46.2 Kaposi's sarcoma of palate
0.474 0.526 0.000
C46.1 Kaposi's sarcoma of soft tissue
0.474 0.526 0.000
C46.0 Kaposi's sarcoma of skin
0.474 0.526 0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified
0.474 0.526 0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system
0.474 0.526 0.000
C47.6 Peripheral nerves of trunk, unspecified
0.474 0.526 0.000
C47.5 Peripheral nerves of pelvis
0.474 0.526 0.000
C47.4 Peripheral nerves of abdomen
0.474 0.526 0.000
C47.3 Peripheral nerves of thorax
0.474 0.526 0.000
C47.2 Peripheral nerves of lower limb, including hip
0.474 0.526 0.000
C47.1 Peripheral nerves of upper limb, including shoulder
0.474 0.526 0.000
C47.0 Peripheral nerves of head, face and neck
0.474 0.526 0.000
C05.1 Soft palate
0.474 0.526 0.000
C00.9 Lip, unspecified
0.474 0.526 0.000
C00.8 Overlapping lesion of lip
0.474 0.526 0.000
C00.6 Commissure of lip
0.474 0.526 0.000
C00.5 Lip, unspecified, inner aspect
0.474 0.526 0.000
C00.4 Lower lip, inner aspect
0.474 0.526 0.000
C00.3 Upper lip, inner aspect
0.474 0.526 0.000
C00.2 External lip, unspecified
0.474 0.526 0.000
C00.1 External lower lip
0.474 0.526 0.000
C91 Lymphoid leukaemia
0.473 0.527 0.000
D00.0 Lip, oral cavity and pharynx
0.473 0.527 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.472 0.527 0.000
C21 Malignant neoplasm of anus and anal canal
0.473 0.527 0.000
C86 Other specified types of T/NK-cell lymphoma
0.472 0.528 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.468 0.532 0.000
C94 Other leukaemias of specified cell type
0.468 0.532 0.000
C84.8 Cutaneous T-cell lymphoma, unspecified
0.464 0.536 0.000
E23.0 Hypopituitarism
0.462 0.538 0.000
D07.6 Other and unspecified male genital organs
0.460 0.540 0.000
D07.3 Other and unspecified female genital organs
0.460 0.540 0.000
D07.0 Endometrium
0.460 0.540 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.460 0.540 0.000
D07.2 Vagina
0.458 0.541 0.000
C93 Monocytic leukaemia
0.456 0.544 0.000
C88 Malignant immunoproliferative diseases
0.456 0.544 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.454 0.546 0.000
E22 Hyperfunction of pituitary gland
0.453 0.547 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.452 0.548 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.449 0.551 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.447 0.553 0.000
C32.0 Glottis
0.444 0.555 0.000
E07.1 Dyshormogenetic goitre
0.441 0.559 0.000
E07.0 Hypersecretion of calcitonin
0.441 0.559 0.000
C70.9 Meninges, unspecified
0.440 0.560 0.000
C70.1 Spinal meninges
0.440 0.560 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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