TreeWAS – Variant ID: rs707936

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E10 Insulin-dependent diabetes mellitus	1.000	0.000
E10.9 Without complications	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002
L40.9 Psoriasis, unspecified	0.997	0.003
M70-M79 Other soft tissue disorders	0.996	0.004
L40 Psoriasis	0.996	0.004
L40-L45 Papulosquamous disorders	0.995	0.005
Chapter XII Diseases of the skin and subcutaneous tissue	0.993	0.007
M79 Other soft tissue disorders, not elsewhere classified	0.992	0.008
Chapter IX Diseases of the circulatory system	0.987	0.013
M79.7 Fibromyalgia	0.985	0.015
I20-I25 Ischaemic heart diseases	0.973	0.027
M79.79 Fibromyalgia (Site unspecified)	0.971	0.029
T66-T78 Other and unspecified effects of external causes	0.969	0.031
S90-S99 Injuries to the ankle and foot	0.952	0.048
I21 Acute myocardial infarction	0.947	0.053
E10.3 With ophthalmic complications	0.946	0.054
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.939	0.061
Chapter XX External causes of morbidity and mortality	0.936	0.064
E65-E68 Obesity and other hyperalimentation	0.934	0.066
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.928	0.072
T78 Adverse effects, not elsewhere classified	0.925	0.075
M86-M90 Other osteopathies	0.924	0.076
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.919	0.081
E10.4 With neurological complications	0.913	0.087
I21.9 Acute myocardial infarction, unspecified	0.910	0.090
I26 Pulmonary embolism	0.906	0.094
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.899	0.101
I10-I15 Hypertensive diseases	0.897	0.103
M50-M54 Other dorsopathies	0.896	0.104
M79.70 Fibromyalgia (Multiple sites)	0.896	0.104
E66 Obesity	0.893	0.107
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.891	0.109
E14 Unspecified diabetes mellitus	0.890	0.110
M72 Fibroblastic disorders	0.888	0.112
T20-T25 Burns and corrosions of external body surface, specified by site	0.888	0.112
T78.4 Allergy, unspecified	0.887	0.113
T88 Other complications of surgical and medical care, not elsewhere classified	0.885	0.115
T93 Sequelae of injuries of lower limb	0.883	0.117
I70-I79 Diseases of arteries, arterioles and capillaries	0.882	0.118
M79.2 Neuralgia and neuritis, unspecified	0.881	0.119
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.878	0.122
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.877	0.123
M54 Dorsalgia	0.876	0.124
M80-M85 Disorders of bone density and structure	0.875	0.125
Chapter XIV Diseases of the genitourinary system	0.875	0.125
T79-T79 Certain early complications of trauma	0.871	0.128
E10.1 With ketoacidosis	0.861	0.139
I12 Hypertensive renal disease	0.859	0.141
L40.5 Arthropathic psoriasis	0.859	0.141
M71 Other bursopathies	0.858	0.142
M89 Other disorders of bone	0.858	0.142
I20 Angina pectoris	0.849	0.151
T88.7 Unspecified adverse effect of drug or medicament	0.849	0.151
M79.6 Pain in limb	0.848	0.152
I21.1 Acute transmural myocardial infarction of inferior wall	0.847	0.153
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.846	0.154
N20-N23 Urolithiasis	0.845	0.155
N10-N16 Renal tubulo-interstitial diseases	0.844	0.156
T36-T50 Poisoning by drugs, medicaments and biological substances	0.840	0.160
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.839	0.161
I05-I09 Chronic rheumatic heart diseases	0.839	0.161
N21 Calculus of lower urinary tract	0.839	0.161
N25-N29 Other disorders of kidney and ureter	0.838	0.162
L43 Lichen planus	0.836	0.164
N21.0 Calculus in bladder	0.834	0.166
E40-E46 Malnutrition	0.830	0.170
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.830	0.170
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.827	0.173
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.826	0.174
S91 Open wound of ankle and foot	0.823	0.177
E14.9 Without complications	0.822	0.178
S90 Superficial injury of ankle and foot	0.821	0.179
M54.4 Lumbago with sciatica	0.820	0.180
T92 Sequelae of injuries of upper limb	0.819	0.181
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.817	0.183
T83.0 Mechanical complication of urinary (indwelling) catheter	0.815	0.185
E10.5 With peripheral circulatory complications	0.815	0.185
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.815	0.185
S20-S29 Injuries to the thorax	0.812	0.188
S32 Fracture of lumbar spine and pelvis	0.810	0.190
E66.9 Obesity, unspecified	0.809	0.191
M76 Enthesopathies of lower limb, excluding foot	0.808	0.192
M77 Other enthesopathies	0.807	0.193
N28 Other disorders of kidney and ureter, not elsewhere classified	0.805	0.195
I20.9 Angina pectoris, unspecified	0.805	0.195
I12.0 Hypertensive renal disease with renal failure	0.801	0.199
E66.8 Other obesity	0.799	0.201
Y84.6 Urinary catheterisation	0.797	0.203
M54.9 Dorsalgia, unspecified	0.797	0.203
L50-L54 Urticaria and erythema	0.795	0.205
N17-N19 Renal failure	0.794	0.206
T93.2 Sequelae of other fractures of lower limb	0.793	0.207
E16 Other disorders of pancreatic internal secretion	0.790	0.210
I77 Other disorders of arteries and arterioles	0.790	0.210
M65-M68 Disorders of synovium and tendon	0.787	0.213
E10.0 With coma	0.786	0.214
S50-S59 Injuries to the elbow and forearm	0.785	0.215
N28.1 Cyst of kidney, acquired	0.785	0.215
T68 Hypothermia	0.783	0.217
E13 Other specified diabetes mellitus	0.783	0.217
T00-T07 Injuries involving multiple body regions	0.781	0.219
Y60-Y69 Misadventures to patients during surgical and medical care	0.781	0.219
N18 Chronic renal failure	0.780	0.220
T79 Certain early complications of trauma, not elsewhere classified	0.780	0.220
M54.5 Low back pain	0.778	0.222
I24 Other acute ischaemic heart diseases	0.778	0.222
S92 Fracture of foot, except ankle	0.777	0.223
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.771	0.229
I71 Aortic aneurysm and dissection	0.770	0.230
T21 Burn and corrosion of trunk	0.769	0.231
T66 Unspecified effects of radiation	0.767	0.233
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.765	0.235
M89.0 Algoneurodystrophy	0.765	0.235
M79.67 Pain in limb (Ankle and foot)	0.763	0.237
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.761	0.239
L40.0 Psoriasis vulgaris	0.760	0.240
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.756	0.244
M71.2 Synovial cyst of popliteal space [Baker]	0.753	0.247
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.752	0.248
T78.3 Angioneurotic oedema	0.750	0.250
M54.96 Dorsalgia, unspecified (Lumbar region)	0.749	0.251
I12.9 Hypertensive renal disease without renal failure	0.747	0.253
M54.46 Lumbago with sciatica (Lumbar region)	0.746	0.254
M80 Osteoporosis with pathological fracture	0.745	0.255
M54.56 Low back pain (Lumbar region)	0.735	0.265
E10.2 With renal complications	0.734	0.266
I21.3 Acute transmural myocardial infarction of unspecified site	0.733	0.267
I07 Rheumatic tricuspid valve diseases	0.733	0.267
M91-M94 Chondropathies	0.732	0.268
M72.2 Plantar fascial fibromatosis	0.731	0.269
I72 Other aneurysm	0.730	0.270
M86 Osteomyelitis	0.730	0.270
S91.3 Open wound of other parts of foot	0.729	0.271
I21.0 Acute transmural myocardial infarction of anterior wall	0.728	0.272
S99 Other and unspecified injuries of ankle and foot	0.727	0.273
I23 Certain current complications following acute myocardial infarction	0.727	0.273
T92.2 Sequelae of fracture at wrist and hand level	0.727	0.273
N18.2 Chronic kidney disease, stage 2	0.723	0.277
X60-X84 Intentional self-harm	0.723	0.277
M45-M49 Spondylopathies	0.723	0.277
Y86 Sequelae of other accidents	0.722	0.278
M89.9 Disorder of bone, unspecified	0.721	0.279
M65 Synovitis and tenosynovitis	0.720	0.280
I11 Hypertensive heart disease	0.719	0.281
N18.9 Chronic renal failure, unspecified	0.718	0.282
Chapter XXII Codes for special purposes	0.718	0.282
E10.8 With unspecified complications	0.717	0.283
E10.7 With multiple complications	0.717	0.283
E10.6 With other specified complications	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
Y84.2 Radiological procedure and radiotherapy	0.716	0.283
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.716	0.284
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.716	0.284
M73 Soft tissue disorders in diseases classified elsewhere	0.714	0.286
I22 Subsequent myocardial infarction	0.714	0.286
L40.8 Other psoriasis	0.714	0.286
L40.4 Guttate psoriasis	0.714	0.286
L40.3 Pustulosis palmaris et plantaris	0.714	0.286
L40.2 Acrodermatitis continua	0.714	0.286
L40.1 Generalised pustular psoriasis	0.714	0.286
I77.1 Stricture of artery	0.713	0.287
L44 Other papulosquamous disorders	0.713	0.287
L41 Parapsoriasis	0.713	0.287
L45 Papulosquamous disorders in diseases classified elsewhere	0.713	0.287
L42 Pityriasis rosea	0.713	0.287
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.712	0.288
T79.3 Post-traumatic wound infection, not elsewhere classified	0.712	0.288
L10-L14 Bullous disorders	0.712	0.288
M79.9 Soft tissue disorder, unspecified	0.711	0.289
M79.4 Hypertrophy of (infrapatellar) fat pad	0.711	0.289
M79.3 Panniculitis, unspecified	0.711	0.289
T93.1 Sequelae of fracture of femur	0.711	0.289
S32.0 Fracture of lumbar vertebra	0.710	0.290
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.709	0.291
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.709	0.291
E46 Unspecified protein-energy malnutrition	0.709	0.291
I00-I02 Acute rheumatic fever	0.707	0.293
X10-X19 Contact with heat and hot substances	0.707	0.293
M79.78 Fibromyalgia (Other)	0.706	0.294
M79.77 Fibromyalgia (Ankle and foot)	0.706	0.294
M79.76 Fibromyalgia (Lower leg)	0.706	0.294
M79.75 Fibromyalgia (Pelvic region and thigh)	0.706	0.294
M79.74 Fibromyalgia (Hand)	0.706	0.294
M79.73 Fibromyalgia (Forearm)	0.706	0.294
M79.72 Fibromyalgia (Upper arm)	0.706	0.294
M79.71 Fibromyalgia (Shoulder region)	0.706	0.294
S70-S79 Injuries to the hip and thigh	0.706	0.294
W50-W64 Exposure to animate mechanical forces	0.704	0.296
L43.9 Lichen planus, unspecified	0.702	0.298
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.702	0.298
S36 Injury of intra-abdominal organs	0.701	0.299
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.701	0.299
M79.65 Pain in limb (Pelvic region and thigh)	0.700	0.300
M79.0 Rheumatism, unspecified	0.699	0.301
M54.47 Lumbago with sciatica (Lumbosacral region)	0.698	0.302
M79.61 Pain in limb (Shoulder region)	0.698	0.302
M89.04 Algoneurodystrophy (Hand)	0.698	0.302
T98 Sequelae of other and unspecified effects of external causes	0.697	0.303
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.697	0.303
X20-X29 Contact with venomous animals and plants	0.696	0.303
T75 Effects of other external causes	0.695	0.305
T74 Maltreatment syndromes	0.695	0.305
T73 Effects of other deprivation	0.695	0.305
T70 Effects of air pressure and water pressure	0.695	0.305
T69 Other effects of reduced temperature	0.695	0.305
T67 Effects of heat and light	0.695	0.305
T71 Asphyxiation	0.695	0.305
Y84.0 Cardiac catheterisation	0.695	0.305
T78.0 Anaphylactic shock due to adverse food reaction	0.694	0.306
T58 Toxic effect of carbon monoxide	0.693	0.307
M79.1 Myalgia	0.693	0.307
X58-X59 Accidental exposure to other and unspecified factors	0.693	0.307
X50-X57 Overexertion, travel and privation	0.692	0.308
I21.4 Acute subendocardial myocardial infarction	0.691	0.309
T88.5 Other complications of anaesthesia	0.691	0.309
M87 Osteonecrosis	0.690	0.310
W20-W49 Exposure to inanimate mechanical forces	0.690	0.310
Chapter I Certain infectious and parasitic diseases	0.689	0.311
E11 Non-insulin-dependent diabetes mellitus	0.687	0.313
I15 Secondary hypertension	0.687	0.313
I77.9 Disorder of arteries and arterioles, unspecified	0.686	0.314
M54.94 Dorsalgia, unspecified (Thoracic region)	0.686	0.314
M79.64 Pain in limb (Hand)	0.686	0.314
L53 Other erythematous conditions	0.686	0.314
M70 Soft tissue disorders related to use, overuse and pressure	0.685	0.315
I24.9 Acute ischaemic heart disease, unspecified	0.685	0.315
T21.2 Burn of second degree of trunk	0.685	0.315
E16.2 Hypoglycaemia, unspecified	0.684	0.316
T88.4 Failed or difficult intubation	0.682	0.318
S22 Fracture of rib(s), sternum and thoracic spine	0.682	0.318
S98 Traumatic amputation of ankle and foot	0.682	0.318
S97 Crushing injury of ankle and foot	0.682	0.318
S96 Injury of muscle and tendon at ankle and foot level	0.682	0.318
S95 Injury of blood vessels at ankle and foot level	0.682	0.318
S94 Injury of nerves at ankle and foot level	0.682	0.318
T59 Toxic effect of other gases, fumes and vapours	0.682	0.318
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.682	0.318
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.680	0.320
M84 Disorders of continuity of bone	0.680	0.320
I21.X Presumed acute myicardial infaction (unconfirmed)	0.679	0.321
N18.3 Chronic kidney disease, stage 3	0.679	0.321
Y89 Sequelae of other external causes	0.679	0.321
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.678	0.322
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.677	0.322
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.677	0.323
S90.8 Other superficial injuries of ankle and foot	0.676	0.324
N13 Obstructive and reflux uropathy	0.675	0.325
A00-A09 Intestinal infectious diseases	0.673	0.327
T95 Sequelae of burns, corrosions and frostbite	0.673	0.327
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.673	0.327
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.673	0.327
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.672	0.327
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.671	0.329
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.671	0.329
S40-S49 Injuries to the shoulder and upper arm	0.671	0.329
Y35-Y36 Legal intervention and operations of war	0.671	0.329
Y10-Y34 Event of undetermined intent	0.671	0.329
Y00-Y09 Assault	0.671	0.329
X85-X99 Assault	0.671	0.329
X30-X39 Exposure to forces of nature	0.671	0.329
X00-X09 Exposure to smoke, fire and flames	0.671	0.329
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.671	0.329
W75-W84 Other accidental threats to breathing	0.671	0.329
W65-W74 Accidental drowning and submersion	0.671	0.329
V98-V99 Other and unspecified transport accidents	0.671	0.329
V95-V97 Air and space transport accidents	0.671	0.329
V90-V94 Water transport accidents	0.671	0.329
V70-V79 Bus occupant injured in transport accident	0.671	0.329
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.671	0.329
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.671	0.329
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.671	0.329
V01-V09 Pedestrian injured in transport accident	0.671	0.329
T94 Sequelae of injuries involving multiple and unspecified body regions	0.670	0.330
S90.3 Contusion of other and unspecified parts of foot	0.670	0.330
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.670	0.330
E67 Other hyperalimentation	0.670	0.330
E68 Sequelae of hyperalimentation	0.670	0.330
T20 Burn and corrosion of head and neck	0.669	0.331
E50-E64 Other nutritional deficiencies	0.669	0.331
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.667	0.333
M81 Osteoporosis without pathological fracture	0.666	0.334
M77.9 Enthesopathy, unspecified	0.666	0.334
V80-V89 Other land transport accidents	0.665	0.335
I28 Other diseases of pulmonary vessels	0.665	0.335
T78.9 Adverse effect, unspecified	0.663	0.336
T78.8 Other adverse effects, not elsewhere classified	0.663	0.336
T86 Failure and rejection of transplanted organs and tissues	0.662	0.337
L20-L30 Dermatitis and eczema	0.661	0.339
A04 Other bacterial intestinal infections	0.661	0.339
M00-M03 Infectious arthropathies	0.657	0.343
I07.1 Tricuspid insufficiency	0.657	0.343
Q20-Q28 Congenital malformations of the circulatory system	0.656	0.344
M79.28 Neuralgia and neuritis, unspecified (Other)	0.654	0.346
Q80-Q89 Other congenital malformations	0.654	0.346
M40-M43 Deforming dorsopathies	0.653	0.347
E66.2 Extreme obesity with alveolar hypoventilation	0.652	0.347
T87 Complications peculiar to reattachment and amputation	0.651	0.348
M82 Osteoporosis in diseases classified elsewhere	0.651	0.348
M88 Paget's disease of bone [osteitis deformans]	0.651	0.349
T78.1 Other adverse food reactions, not elsewhere classified	0.650	0.350
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.650	0.350
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.649	0.351
N26 Unspecified contracted kidney	0.647	0.353
T63 Toxic effect of contact with venomous animals	0.646	0.354
M65.3 Trigger finger	0.646	0.354
T93.0 Sequelae of open wound of lower limb	0.646	0.354
N13.3 Other and unspecified hydronephrosis	0.646	0.354
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.644	0.356
S37 Injury of urinary and pelvic organs	0.644	0.356
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.644	0.356
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.644	0.356
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.644	0.356
S31 Open wound of abdomen, lower back and pelvis	0.644	0.356
T15-T19 Effects of foreign body entering through natural orifice	0.644	0.356
I13 Hypertensive heart and renal disease	0.643	0.357
S54 Injury of nerves at forearm level	0.643	0.357
M89.8 Other specified disorders of bone	0.642	0.357
S32.7 Multiple fractures of lumbar spine and pelvis	0.642	0.358
A04.8 Other specified bacterial intestinal infections	0.642	0.358
N21.1 Calculus in urethra	0.641	0.359
E66.1 Drug-induced obesity	0.640	0.360
E66.0 Obesity due to excess calories	0.640	0.360
S29 Other and unspecified injuries of thorax	0.639	0.361
S32.00 Fracture of lumbar vertebra (closed)	0.639	0.361
V10-V19 Pedal cyclist injured in transport accident	0.638	0.362
E14.8 With unspecified complications	0.638	0.362
E14.7 With multiple complications	0.638	0.362
E14.6 With other specified complications	0.638	0.362
E14.5 With peripheral circulatory complications	0.638	0.362
E14.4 With neurological complications	0.638	0.362
E14.2 Withrenal complications	0.638	0.362
E14.1 With ketoacidosis	0.638	0.362
E14.0 With coma	0.638	0.362
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.638	0.362
T83.1 Mechanical complication of other urinary devices and implants	0.638	0.362
S30 Superficial injury of abdomen, lower back and pelvis	0.637	0.363
M72.9 Fibroblastic disorder, unspecified	0.637	0.363
M72.8 Other fibroblastic disorders	0.637	0.363
M72.6 Necrotizing fasciitis	0.637	0.363
M72.5 Fasciitis, not elsewhere classified	0.637	0.363
M72.4 Pseudosarcomatous fibromatosis	0.637	0.363
M72.3 Nodular fasciitis	0.637	0.363
M72.1 Knuckle pads	0.637	0.363
T25 Burn and corrosion of ankle and foot	0.637	0.363
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.637	0.363
I05 Rheumatic mitral valve diseases	0.635	0.365
T88.9 Complication of surgical and medical care, unspecified	0.635	0.365
T88.3 Malignant hyperthermia due to anaesthesis	0.635	0.365
T88.2 Shock due to anaesthesia	0.635	0.365
T88.1 Other complications following immunisation, not elsewhere classified	0.635	0.365
T88.0 Infection following immunisation	0.635	0.365
M76.6 Achilles tendinitis	0.635	0.365
Y88 Sequelae of surgical and medical care as external cause	0.634	0.366
T11 Other injuries of upper limb, level unspecified	0.634	0.366
L43.8 Other lichen planus	0.634	0.366
E65 Localised adiposity	0.633	0.367
T93.8 Sequelae of other specified injuries of lower limb	0.633	0.367
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.633	0.367
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.633	0.367
T93.4 Sequelae of injury of nerve of lower limb	0.633	0.367
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.632	0.368
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.632	0.368
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.632	0.368
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.632	0.368
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.632	0.368
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.632	0.368
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.632	0.368
T82.1 Mechanical complication of cardiac electronic device	0.632	0.368
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.631	0.369
S92.0 Fracture of calcaneus	0.631	0.369
M71.3 Other bursal cyst	0.631	0.369
T93.9 Sequelae of unspecified injury of lower limb	0.631	0.369
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.630	0.370
E16.0 Drug-induced hypoglycaemia without coma	0.630	0.370
M76.8 Other enthesopathies of lower limb, excluding foot	0.630	0.370
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.630	0.370
M77.5 Other enthesopathy of foot	0.630	0.370
M79.5 Residual foreign body in soft tissue	0.629	0.370
E15 Nondiabetic hypoglycaemic coma	0.629	0.371
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.629	0.371
T83.2 Mechanical complication of graft of urinary organ	0.629	0.371
S10-S19 Injuries to the neck	0.629	0.371
M53 Other dorsopathies, not elsewhere classified	0.629	0.371
S32.3 Fracture of ilium	0.628	0.372
M54.8 Other dorsalgia	0.628	0.372
M54.0 Panniculitis affecting regions of neck and back	0.628	0.372
E13.9 Without complications	0.628	0.372
T50.9 Other and unspecified drugs, medicaments and biological substances	0.628	0.372
M83 Adult osteomalacia	0.628	0.372
I09 Other rheumatic heart diseases	0.627	0.372
Y52 Agents primarily affecting the cardiovascular system	0.626	0.374
T02 Fractures involving multiple body regions	0.624	0.376
N18.5 Chronic kidney disease, stage 5	0.624	0.376
M80.0 Postmenopausal osteoporosis with pathological fracture	0.624	0.376
T13 Other injuries of lower limb, level unspecified	0.623	0.377
T79.7 Traumatic subcutaneous emphysema	0.623	0.377
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.623	0.377
S32.5 Fracture of pubis	0.620	0.380
M90 Osteopathies in diseases classified elsewhere	0.619	0.381
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.618	0.381
I72.9 Aneurysm of unspecified site	0.617	0.383
T36 Poisoning by systemic antibiotics	0.616	0.384
S59 Other and unspecified injuries of forearm	0.616	0.384
M71.9 Bursopathy, unspecified	0.615	0.384
M71.8 Other specified bursopathies	0.615	0.384
M71.5 Other bursitis, not elsewhere classified	0.615	0.384
M71.4 Calcium deposit in bursa	0.615	0.384
M71.1 Other infective bursitis	0.615	0.384
M71.0 Abscess of bursa	0.615	0.384
M89.6 Osteopathy after poliomyelitis	0.615	0.385
M89.5 Osteolysis	0.615	0.385
M89.4 Other hypertrophic osteo-arthropathy	0.615	0.385
M89.3 Hypertrophy of bone	0.615	0.385
M89.2 Other disorders of bone development and growth	0.615	0.385
M89.1 Epiphyseal arrest	0.615	0.385
I74 Arterial embolism and thrombosis	0.615	0.385
S50 Superficial injury of forearm	0.615	0.385
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.614	0.386
V40-V49 Car occupant injured in transport accident	0.613	0.387
T23 Burn and corrosion of wrist and hand	0.613	0.387
T14 Injury of unspecified body region	0.612	0.388
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.609	0.390
M79.69 Pain in limb (Site unspecified)	0.609	0.391
M79.68 Pain in limb (Other)	0.608	0.392
T31 Burns classified according to extent of body surface involved	0.607	0.393
I70 Atherosclerosis	0.606	0.393
S92.2 Fracture of other tarsal bone(s)	0.606	0.394
T81 Complications of procedures, not elsewhere classified	0.606	0.394
Q60-Q64 Congenital malformations of the urinary system	0.606	0.394
E16.1 Other hypoglycaemia	0.606	0.394
N22 Calculus of urinary tract in diseases classified elsewhere	0.606	0.394
E11.6 With other specified complications	0.605	0.395
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.605	0.395
N15 Other renal tubulo-interstitial diseases	0.605	0.395
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.605	0.395
Q38-Q45 Other congenital malformations of the digestive system	0.605	0.395
M65.1 Other infective (teno)synovitis	0.604	0.395
M65.4 Radial styloid tenosynovitis [de Quervain]	0.604	0.396
S27 Injury of other and unspecified intrathoracic organs	0.603	0.396
M54.3 Sciatica	0.602	0.398
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.602	0.398
T41 Poisoning by anaesthetics and therapeutic gases	0.602	0.398
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.602	0.398
T65 Toxic effect of other and unspecified substances	0.602	0.398
T62 Toxic effect of other noxious substances eaten as food	0.602	0.398
T61 Toxic effect of noxious substances eaten as seafood	0.602	0.398
T60 Toxic effect of pesticides	0.602	0.398
T57 Toxic effect of other inorganic substances	0.602	0.398
T56 Toxic effect of metals	0.602	0.398
T54 Toxic effect of corrosive substances	0.602	0.398
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.602	0.398
T52 Toxic effect of organic solvents	0.602	0.398
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.602	0.398
T55 Toxic effect of soaps and detergents	0.602	0.398
I06 Rheumatic aortic valve diseases	0.602	0.398
N21.9 Calculus of lower urinary tract, unspecified	0.601	0.398
N21.8 Other lower urinary tract calculus	0.601	0.398
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.601	0.399
N27 Small kidney of unknown cause	0.601	0.399
N25 Disorders resulting from impaired renal tubular function	0.601	0.399
E14.3 With ophthalmic complications	0.601	0.399
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.600	0.400
M85 Other disorders of bone density and structure	0.600	0.400
V20-V29 Motorcycle rider injured in transport accident	0.599	0.400
L43.3 Subacute (active) lichen planus	0.599	0.401
L43.2 Lichenoid drug reaction	0.599	0.401
L43.1 Bullous lichen planus	0.599	0.401
L43.0 Hypertrophic lichen planus	0.599	0.401
S92.1 Fracture of talus	0.598	0.402
M54.1 Radiculopathy	0.597	0.402
S91.1 Open wound of toe(s) without damage to nail	0.596	0.404
M47 Spondylosis	0.596	0.404
E44 Protein-energy malnutrition of moderate and mild degree	0.595	0.405
E45 Retarded development following protein-energy malnutrition	0.595	0.405
E43 Unspecified severe protein-energy malnutrition	0.595	0.405
E42 Marasmic kwashiorkor	0.595	0.405
E41 Nutritional marasmus	0.595	0.405
E40 Kwashiorkor	0.595	0.405
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.595	0.405
M79.62 Pain in limb (Upper arm)	0.595	0.405
A08 Viral and other specified intestinal infections	0.594	0.406
N00-N08 Glomerular diseases	0.593	0.407
M65.34 Trigger finger-Hand	0.593	0.407
Y84.9 Medical procedure, unspecified	0.592	0.408
Y84.7 Blood-sampling	0.592	0.408
Y84.5 Insertion of gastric or duodenal sound	0.592	0.408
Y84.3 Shock therapy	0.592	0.408
I11.9 Hypertensive heart disease without (congestive) heart failure	0.592	0.408
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.591	0.409
L53.9 Erythematous condition, unspecified	0.591	0.409
N28.8 Other specified disorders of kidney and ureter	0.591	0.409

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations