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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs71595688
log Bayes Factor = 19.2287
Chromosome 4   position 53,217,472  (GRCh37) Explore rs71595688 on Ensembl!
Variant rs71595688 is part of Cluster X0055

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
C79 Secondary malignant neoplasm of other sites
0.998 0.002 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.998 0.002 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.997 0.003 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.997 0.003 0.000
I30-I52 Other forms of heart disease
0.995 0.005 0.000
R50-R69 General symptoms and signs
0.993 0.007 0.000
R55 Syncope and collapse
0.989 0.011 0.000
Chapter XXI Factors influencing health status and contact with health services
0.989 0.011 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.984 0.016 0.000
R10 Abdominal and pelvic pain
0.981 0.019 0.000
S80-S89 Injuries to the knee and lower leg
0.979 0.021 0.000
R10.4 Other and unspecified abdominal pain
0.979 0.021 0.000
Chapter XX External causes of morbidity and mortality
0.978 0.022 0.000
Chapter VII Diseases of the eye and adnexa
0.977 0.023 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.975 0.025 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.971 0.029 0.000
C15-C26 Malignant neoplasms of digestive organs
0.968 0.032 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.960 0.040 0.000
Chapter V Mental and behavioural disorders
0.959 0.041 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.952 0.048 0.000
I73 Other peripheral vascular diseases
0.950 0.050 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.947 0.053 0.000
I35 Nonrheumatic aortic valve disorders
0.946 0.054 0.000
C77.2 Intra-abdominal lymph nodes
0.944 0.056 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.941 0.059 0.000
I73.9 Peripheral vascular disease, unspecified
0.934 0.066 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.934 0.066 0.000
Chapter X Diseases of the respiratory system
0.929 0.071 0.000
Z47 Other orthopaedic follow-up care
0.926 0.074 0.000
R51 Headache
0.926 0.074 0.000
I31 Other diseases of pericardium
0.918 0.082 0.000
C78.7 Secondary malignant neoplasm of liver
0.913 0.087 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.912 0.088 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.911 0.089 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.910 0.090 0.000
I35.0 Aortic (valve) stenosis
0.910 0.090 0.000
C78.0 Secondary malignant neoplasm of lung
0.908 0.092 0.000
J30-J39 Other diseases of upper respiratory tract
0.908 0.092 0.000
S00-S09 Injuries to the head
0.904 0.096 0.000
R26 Abnormalities of gait and mobility
0.897 0.103 0.000
R18 Ascites
0.896 0.104 0.000
C77.5 Intrapelvic lymph nodes
0.895 0.105 0.000
H40-H42 Glaucoma
0.892 0.108 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.892 0.108 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.891 0.109 0.000
R12 Heartburn
0.891 0.109 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.889 0.111 0.000
S83.2 Tear of meniscus, current
0.886 0.114 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.886 0.114 0.000
C18 Malignant neoplasm of colon
0.882 0.118 0.000
I42 Cardiomyopathy
0.880 0.120 0.000
C77.1 Intrathoracic lymph nodes
0.880 0.120 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.878 0.122 0.000
R13 Dysphagia
0.875 0.125 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.875 0.125 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.873 0.127 0.000
C50-C50 Malignant neoplasm of breast
0.872 0.128 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.870 0.130 0.000
I34 Nonrheumatic mitral valve disorders
0.868 0.132 0.000
S82 Fracture of lower leg, including ankle
0.861 0.139 0.000
S20-S29 Injuries to the thorax
0.860 0.140 0.000
C80 Malignant neoplasm without specification of site
0.853 0.147 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.853 0.147 0.000
C79.2 Secondary malignant neoplasm of skin
0.853 0.147 0.000
H53-H54 Visual disturbances and blindness
0.851 0.149 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.851 0.149 0.000
C78.2 Secondary malignant neoplasm of pleura
0.851 0.149 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.851 0.149 0.000
S40-S49 Injuries to the shoulder and upper arm
0.849 0.151 0.000
Z51 Other medical care
0.849 0.151 0.000
S60-S69 Injuries to the wrist and hand
0.849 0.151 0.000
E70-E90 Metabolic disorders
0.847 0.153 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.843 0.157 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.842 0.158 0.000
R25 Abnormal involuntary movements
0.839 0.161 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.837 0.163 0.000
J32 Chronic sinusitis
0.837 0.163 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.837 0.163 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.837 0.163 0.000
T39.1 4-Aminophenol derivatives
0.836 0.164 0.000
I20-I25 Ischaemic heart diseases
0.834 0.166 0.000
J33 Nasal polyp
0.833 0.167 0.000
D10-D36 Benign neoplasms
0.832 0.168 0.000
Chapter VIII Diseases of the ear and mastoid process
0.831 0.169 0.000
H40 Glaucoma
0.831 0.169 0.000
I31.3 Pericardial effusion (noninflammatory)
0.829 0.171 0.000
H00 Hordeolum and chalazion
0.827 0.173 0.000
Z40 Prophylactic surgery
0.826 0.174 0.000
C18.7 Sigmoid colon
0.825 0.175 0.000
I46 Cardiac arrest
0.824 0.176 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.824 0.176 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.822 0.178 0.000
R14 Flatulence and related conditions
0.819 0.181 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.817 0.183 0.000
Z53.8 Procedure not carried out for other reasons
0.817 0.183 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.815 0.184 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.815 0.185 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.815 0.185 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.815 0.185 0.000
Z53.0 Procedure not carried out because of contraindication
0.814 0.186 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.814 0.186 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.809 0.191 0.000
Z48 Other surgical follow-up care
0.808 0.192 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.808 0.192 0.000
C77.8 Lymph nodes of multiple regions
0.808 0.192 0.000
R52 Pain, not elsewhere classified
0.805 0.195 0.000
R17 Unspecified jaundice
0.805 0.195 0.000
I71 Aortic aneurysm and dissection
0.805 0.195 0.000
C77.0 Lymph nodes of head, face and neck
0.805 0.195 0.000
S70-S79 Injuries to the hip and thigh
0.804 0.196 0.000
Y43 Primarily systemic agents
0.803 0.197 0.000
I50 Heart failure
0.802 0.198 0.000
T66-T78 Other and unspecified effects of external causes
0.800 0.200 0.000
C15 Malignant neoplasm of oesophagus
0.799 0.201 0.000
C77.9 Lymph node, unspecified
0.799 0.201 0.000
Z95.1 Presence of aortocoronary bypass graft
0.797 0.203 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.793 0.207 0.000
Z45 Adjustment and management of implanted device
0.793 0.207 0.000
H00.1 Chalazion
0.790 0.210 0.000
Z52 Donors of organs and tissues
0.790 0.210 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.790 0.210 0.000
V10-V19 Pedal cyclist injured in transport accident
0.789 0.211 0.000
Z51.5 Palliative care
0.788 0.212 0.000
I42.9 Cardiomyopathy, unspecified
0.787 0.213 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.781 0.219 0.000
C50 Malignant neoplasm of breast
0.780 0.220 0.000
Y57 Other and unspecified drugs and medicaments
0.780 0.220 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.779 0.220 0.000
Z83 Family history of other specific disorders
0.779 0.221 0.000
C77.4 Inguinal and lower limb lymph nodes
0.778 0.222 0.000
H40.2 Primary angle-closure glaucoma
0.777 0.223 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.775 0.225 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.775 0.225 0.000
R60 Oedema, not elsewhere classified
0.775 0.225 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.774 0.226 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.772 0.228 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.772 0.228 0.000
Z95.0 Presence of cardiac pacemaker
0.772 0.228 0.000
I70 Atherosclerosis
0.771 0.228 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.771 0.229 0.000
R20 Disturbances of skin sensation
0.769 0.231 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.768 0.232 0.000
C16 Malignant neoplasm of stomach
0.768 0.232 0.000
C51-C58 Malignant neoplasms of female genital organs
0.766 0.233 0.000
S81 Open wound of lower leg
0.764 0.236 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.763 0.237 0.000
Z51.1 Chemotherapy session for neoplasm
0.763 0.237 0.000
R10.2 Pelvic and perineal pain
0.763 0.237 0.000
T79-T79 Certain early complications of trauma
0.761 0.239 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.760 0.240 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.759 0.241 0.000
I31.9 Disease of pericardium, unspecified
0.759 0.241 0.000
T39.0 Salicylates
0.758 0.241 0.000
F30-F39 Mood [affective] disorders
0.758 0.242 0.000
S82.1 Fracture of upper end of tibia
0.757 0.243 0.000
J33.9 Nasal polyp, unspecified
0.756 0.244 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.756 0.244 0.000
I45 Other conduction disorders
0.754 0.246 0.000
H10-H13 Disorders of conjunctiva
0.754 0.246 0.000
I33 Acute and subacute endocarditis
0.753 0.247 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.753 0.247 0.000
W00-W19 Falls
0.753 0.247 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.753 0.247 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.753 0.247 0.000
S50-S59 Injuries to the elbow and forearm
0.752 0.248 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.752 0.248 0.000
I51 Complications and ill-defined descriptions of heart disease
0.750 0.250 0.000
Chapter XIV Diseases of the genitourinary system
0.750 0.250 0.000
Z73 Problems related to life-management difficulty
0.748 0.252 0.000
S00 Superficial injury of head
0.746 0.254 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.745 0.255 0.000
S42 Fracture of shoulder and upper arm
0.745 0.255 0.000
I34.0 Mitral (valve) insufficiency
0.744 0.256 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.741 0.259 0.000
R54 Senility
0.741 0.259 0.000
R61 Hyperhidrosis
0.741 0.259 0.000
I78 Diseases of capillaries
0.740 0.260 0.000
I20 Angina pectoris
0.740 0.260 0.000
J32.0 Chronic maxillary sinusitis
0.737 0.263 0.000
L20-L30 Dermatitis and eczema
0.737 0.263 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.737 0.263 0.000
H55-H59 Other disorders of eye and adnexa
0.736 0.264 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.736 0.264 0.000
J00-J06 Acute upper respiratory infections
0.736 0.264 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.734 0.266 0.000
F99-F99 Unspecified mental disorder
0.734 0.266 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.734 0.266 0.000
J09-J18 Influenza and pneumonia
0.733 0.267 0.000
D22 Melanocytic naevi
0.731 0.269 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.729 0.271 0.000
J35 Chronic diseases of tonsils and adenoids
0.728 0.272 0.000
C80.9 Malignant neoplasm, unspecified
0.726 0.274 0.000
Z41 Procedures for purposes other than remedying health state
0.724 0.276 0.000
R25.3 Fasciculation
0.724 0.276 0.000
R68 Other general symptoms and signs
0.723 0.277 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.723 0.277 0.000
N30-N39 Other diseases of urinary system
0.723 0.277 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.723 0.277 0.000
I20.0 Unstable angina
0.723 0.277 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.722 0.278 0.000
J34 Other disorders of nose and nasal sinuses
0.722 0.278 0.000
Z98 Other postsurgical states
0.722 0.278 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.722 0.278 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.721 0.279 0.000
C20 Malignant neoplasm of rectum
0.720 0.280 0.000
E78.5 Hyperlipidaemia, unspecified
0.720 0.280 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.719 0.281 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.718 0.282 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.716 0.284 0.000
C79.6 Secondary malignant neoplasm of ovary
0.716 0.284 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.716 0.284 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.716 0.284 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.716 0.284 0.000
S90-S99 Injuries to the ankle and foot
0.716 0.284 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.716 0.284 0.000
J32.9 Chronic sinusitis, unspecified
0.715 0.285 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.715 0.285 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.715 0.285 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.715 0.285 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I37 Pulmonary valve disorders
0.713 0.287 0.000
I36 Nonrheumatic tricuspid valve disorders
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
I30 Acute pericarditis
0.713 0.287 0.000
Z93 Artificial opening status
0.713 0.287 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.713 0.287 0.000
H54 Blindness and low vision
0.713 0.287 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.712 0.288 0.000
R62 Lack of expected normal physiological development
0.712 0.288 0.000
R57 Shock, not elsewhere classified
0.712 0.288 0.000
R64 Cachexia
0.712 0.288 0.000
R58 Haemorrhage, not elsewhere classified
0.712 0.288 0.000
H90-H95 Other disorders of ear
0.709 0.291 0.000
I50.1 Left ventricular failure
0.709 0.291 0.000
R47-R49 Symptoms and signs involving speech and voice
0.709 0.291 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.709 0.291 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.708 0.292 0.000
S02 Fracture of skull and facial bones
0.707 0.293 0.000
S06 Intracranial injury
0.707 0.293 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.707 0.293 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.706 0.293 0.000
Z42 Follow-up care involving plastic surgery
0.706 0.294 0.000
J30 Vasomotor and allergic rhinitis
0.706 0.294 0.000
Z54 Convalescence
0.705 0.294 0.000
Z49 Care involving dialysis
0.705 0.294 0.000
Z44 Fitting and adjustment of external prosthetic device
0.705 0.294 0.000
Z43 Attention to artificial openings
0.705 0.295 0.000
Y43.3 Other antineoplastic drugs
0.704 0.296 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.704 0.296 0.000
R10.0 Acute abdomen
0.703 0.296 0.000
E16 Other disorders of pancreatic internal secretion
0.703 0.296 0.000
R06 Abnormalities of breathing
0.702 0.297 0.000
S09 Other and unspecified injuries of head
0.702 0.298 0.000
S89 Other and unspecified injuries of lower leg
0.702 0.298 0.000
S88 Traumatic amputation of lower leg
0.702 0.298 0.000
S87 Crushing injury of lower leg
0.702 0.298 0.000
S86 Injury of muscle and tendon at lower leg level
0.702 0.298 0.000
S85 Injury of blood vessels at lower leg level
0.702 0.298 0.000
S84 Injury of nerves at lower leg level
0.702 0.298 0.000
S80 Superficial injury of lower leg
0.702 0.298 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.701 0.299 0.000
Y35-Y36 Legal intervention and operations of war
0.701 0.299 0.000
Y10-Y34 Event of undetermined intent
0.701 0.299 0.000
Y00-Y09 Assault
0.701 0.299 0.000
X85-X99 Assault
0.701 0.299 0.000
X60-X84 Intentional self-harm
0.701 0.299 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.701 0.299 0.000
X50-X57 Overexertion, travel and privation
0.701 0.299 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.701 0.299 0.000
X30-X39 Exposure to forces of nature
0.701 0.299 0.000
X20-X29 Contact with venomous animals and plants
0.701 0.299 0.000
X10-X19 Contact with heat and hot substances
0.701 0.299 0.000
X00-X09 Exposure to smoke, fire and flames
0.701 0.299 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.701 0.299 0.000
W75-W84 Other accidental threats to breathing
0.701 0.299 0.000
W65-W74 Accidental drowning and submersion
0.701 0.299 0.000
W50-W64 Exposure to animate mechanical forces
0.701 0.299 0.000
V98-V99 Other and unspecified transport accidents
0.701 0.299 0.000
V95-V97 Air and space transport accidents
0.701 0.299 0.000
V90-V94 Water transport accidents
0.701 0.299 0.000
V80-V89 Other land transport accidents
0.701 0.299 0.000
V70-V79 Bus occupant injured in transport accident
0.701 0.299 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.701 0.299 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.701 0.299 0.000
V40-V49 Car occupant injured in transport accident
0.701 0.299 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.701 0.299 0.000
V20-V29 Motorcycle rider injured in transport accident
0.701 0.299 0.000
V01-V09 Pedestrian injured in transport accident
0.701 0.299 0.000
I47 Paroxysmal tachycardia
0.701 0.299 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.699 0.301 0.000
I72 Other aneurysm
0.699 0.301 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.699 0.301 0.000
Chapter XXII Codes for special purposes
0.698 0.302 0.000
R27 Other lack of coordination
0.696 0.303 0.000
H53 Visual disturbances
0.695 0.305 0.000
T51 Toxic effect of alcohol
0.694 0.305 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.694 0.306 0.000
N39 Other disorders of urinary system
0.694 0.306 0.000
I05-I09 Chronic rheumatic heart diseases
0.694 0.306 0.000
H01 Other inflammation of eyelid
0.694 0.306 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.694 0.306 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.694 0.306 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.694 0.306 0.000
C21 Malignant neoplasm of anus and anal canal
0.694 0.306 0.000
C17 Malignant neoplasm of small intestine
0.694 0.306 0.000
C23 Malignant neoplasm of gallbladder
0.694 0.306 0.000
D24 Benign neoplasm of breast
0.693 0.306 0.000
W20-W49 Exposure to inanimate mechanical forces
0.693 0.307 0.000
J60-J70 Lung diseases due to external agents
0.693 0.307 0.000
Z97 Presence of other devices
0.692 0.308 0.000
F10.0 Acute intoxication
0.691 0.309 0.000
L60-L75 Disorders of skin appendages
0.690 0.310 0.000
S64 Injury of nerves at wrist and hand level
0.690 0.310 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.688 0.312 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.688 0.312 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.688 0.312 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.688 0.312 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.688 0.312 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.688 0.312 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.688 0.312 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.688 0.312 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.688 0.312 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.688 0.312 0.000
T36 Poisoning by systemic antibiotics
0.688 0.312 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.688 0.312 0.000
F80-F89 Disorders of psychological development
0.688 0.312 0.000
F70-F79 Mental retardation
0.688 0.312 0.000
F60-F69 Disorders of adult personality and behaviour
0.688 0.312 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.688 0.312 0.000
I34.1 Mitral (valve) prolapse
0.687 0.313 0.000
D25 Leiomyoma of uterus
0.686 0.314 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.684 0.316 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.684 0.316 0.000
R20.2 Paraesthesia of skin
0.684 0.316 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.683 0.317 0.000
Z83.3 Family history of diabetes mellitus
0.683 0.317 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.683 0.317 0.000
S82.10 Fracture of upper end of tibia (closed)
0.683 0.317 0.000
Z75 Problems related to medical facilities and other health care
0.682 0.318 0.000
C18.2 Ascending colon
0.681 0.319 0.000
I42.2 Other hypertrophic cardiomyopathy
0.681 0.319 0.000
I73.8 Other specified peripheral vascular diseases
0.681 0.319 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.681 0.319 0.000
C18.9 Colon, unspecified
0.681 0.319 0.000
C50.4 Upper-outer quadrant of breast
0.681 0.319 0.000
I35.9 Aortic valve disorder, unspecified
0.678 0.321 0.000
I35.8 Other aortic valve disorders
0.678 0.321 0.000
E73 Lactose intolerance
0.678 0.322 0.000
I46.9 Cardiac arrest, unspecified
0.677 0.323 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.676 0.324 0.000
Y59 Other and unspecified vaccines and biological substances
0.674 0.326 0.000
Y58 Bacterial vaccines
0.674 0.326 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.674 0.326 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.674 0.326 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.674 0.326 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.674 0.326 0.000
Y52 Agents primarily affecting the cardiovascular system
0.674 0.326 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.674 0.326 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.674 0.326 0.000
Y48 Anaesthetics and therapeutic gases
0.674 0.326 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.674 0.326 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.674 0.326 0.000
Y44 Agents primarily affecting blood constituents
0.674 0.326 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.674 0.326 0.000
I24 Other acute ischaemic heart diseases
0.672 0.328 0.000
R56 Convulsions, not elsewhere classified
0.671 0.328 0.000
D00-D09 In situ neoplasms
0.671 0.328 0.000
Z48.8 Other specified surgical follow-up care
0.670 0.330 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.670 0.330 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.670 0.330 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.669 0.330 0.000
S83.7 Injury to multiple structures of knee
0.669 0.331 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.669 0.331 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.669 0.331 0.000
S83.3 Tear of articular cartilage of knee, current
0.669 0.331 0.000
S83.1 Dislocation of knee
0.669 0.331 0.000
S83.0 Dislocation of patella
0.669 0.331 0.000
S01 Open wound of head
0.669 0.331 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.668 0.332 0.000
J33.8 Other polyp of sinus
0.666 0.334 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.666 0.334 0.000
Y57.9 Drug or medicament, unspecified
0.665 0.334 0.000
C50.9 Breast, unspecified
0.665 0.335 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.664 0.336 0.000
D36 Benign neoplasm of other and unspecified sites
0.664 0.336 0.000
R52.1 Chronic intractable pain
0.662 0.338 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.661 0.339 0.000
R02 Gangrene, not elsewhere classified
0.661 0.339 0.000
F03 Unspecified dementia
0.660 0.340 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.660 0.340 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.660 0.340 0.000
C56 Malignant neoplasm of ovary
0.660 0.340 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.660 0.340 0.000
S82.3 Fracture of lower end of tibia
0.659 0.341 0.000
I35.1 Aortic (valve) insufficiency
0.659 0.341 0.000
I21 Acute myocardial infarction
0.659 0.341 0.000
I31.8 Other specified diseases of pericardium
0.658 0.341 0.000
I31.2 Haemopericardium, not elsewhere classified
0.658 0.341 0.000
I31.1 Chronic constrictive pericarditis
0.658 0.341 0.000
I31.0 Chronic adhesive pericarditis
0.658 0.341 0.000
D23 Other benign neoplasms of skin
0.658 0.342 0.000
R04 Haemorrhage from respiratory passages
0.658 0.342 0.000
H60-H62 Diseases of external ear
0.658 0.342 0.000
S82.6 Fracture of lateral malleolus
0.657 0.343 0.000
N39.4 Other specified urinary incontinence
0.657 0.343 0.000
F17.1 Harmful use
0.656 0.344 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.656 0.344 0.000
T93 Sequelae of injuries of lower limb
0.655 0.345 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.654 0.345 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.654 0.346 0.000
I73.0 Raynaud's syndrome
0.654 0.346 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.654 0.346 0.000
E20-E35 Disorders of other endocrine glands
0.654 0.346 0.000
L40-L45 Papulosquamous disorders
0.654 0.346 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.654 0.346 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.653 0.347 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.653 0.347 0.000
T39.4 Antirheumatics, not elsewhere classified
0.653 0.347 0.000
T39.2 Pyrazolone derivatives
0.653 0.347 0.000
T87 Complications peculiar to reattachment and amputation
0.652 0.347 0.000
T86 Failure and rejection of transplanted organs and tissues
0.652 0.347 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.652 0.347 0.000
T68 Hypothermia
0.653 0.347 0.000
Y40 Systemic antibiotics
0.652 0.348 0.000
J37 Chronic laryngitis and laryngotracheitis
0.651 0.349 0.000
J36 Peritonsillar abscess
0.651 0.349 0.000
Z52.4 Kidney donor
0.651 0.349 0.000
Z45.8 Adjustment and management of other implanted devices
0.650 0.350 0.000
E16.2 Hypoglycaemia, unspecified
0.649 0.351 0.000
C25 Malignant neoplasm of pancreas
0.649 0.351 0.000
S08 Traumatic amputation of part of head
0.648 0.351 0.000
S07 Crushing injury of head
0.648 0.351 0.000
S05 Injury of eye and orbit
0.648 0.351 0.000
S04 Injury of cranial nerves
0.648 0.351 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.648 0.351 0.000
S22.4 Multiple fractures of ribs
0.648 0.352 0.000
Z91.5 Personal history of self-harm
0.648 0.352 0.000
S68 Traumatic amputation of wrist and hand
0.647 0.352 0.000
C77.3 Axillary and upper limb lymph nodes
0.647 0.353 0.000
E88 Other metabolic disorders
0.647 0.353 0.000
S82.4 Fracture of fibula alone
0.646 0.354 0.000
E87.5 Hyperkalaemia
0.645 0.355 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.645 0.355 0.000
C60-C63 Malignant neoplasms of male genital organs
0.645 0.355 0.000
Z95.2 Presence of prosthetic heart valve
0.644 0.356 0.000
H40.9 Glaucoma, unspecified
0.644 0.356 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.643 0.357 0.000
R26.3 Immobility
0.643 0.357 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.643 0.357 0.000
R26.1 Paralytic gait
0.643 0.357 0.000
R26.0 Ataxic gait
0.643 0.357 0.000
N75 Diseases of Bartholin's gland
0.642 0.358 0.000
S62 Fracture at wrist and hand level
0.642 0.358 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.641 0.359 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.641 0.359 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.641 0.359 0.000
S72 Fracture of femur
0.641 0.359 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.640 0.360 0.000
H42 Glaucoma in diseases classified elsewhere
0.640 0.360 0.000
C71 Malignant neoplasm of brain
0.639 0.361 0.000
R21 Rash and other nonspecific skin eruption
0.638 0.362 0.000
Y42.5 Other oestrogens and progestogens
0.638 0.362 0.000
C18.4 Transverse colon
0.637 0.362 0.000
L10-L14 Bullous disorders
0.637 0.363 0.000
C15.5 Lower third of oesophagus
0.636 0.364 0.000
Z83.5 Family history of eye and ear disorders
0.636 0.364 0.000
H43-H45 Disorders of vitreous body and globe
0.636 0.364 0.000
Z48.9 Surgical follow-up care, unspecified
0.636 0.364 0.000
F32 Depressive episode
0.636 0.364 0.000
E50-E64 Other nutritional deficiencies
0.636 0.364 0.000
E40-E46 Malnutrition
0.635 0.365 0.000
S27 Injury of other and unspecified intrathoracic organs
0.634 0.366 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.634 0.366 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.633 0.367 0.000
H40.1 Primary open-angle glaucoma
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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