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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs7221360
log Bayes Factor = 16.9886
Chromosome 17   position 52,448,143  (GRCh37) Explore rs7221360 on Ensembl!
Variant rs7221360 is part of Cluster X0290

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.998 0.002 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
M20-M25 Other joint disorders
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.995 0.005 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.994 0.006 0.000
I21 Acute myocardial infarction
0.991 0.009 0.000
I50 Heart failure
0.991 0.009 0.000
I25 Chronic ischaemic heart disease
0.989 0.011 0.000
Z92 Personal history of medical treatment
0.986 0.014 0.000
K70-K77 Diseases of liver
0.984 0.016 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.983 0.017 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.981 0.019 0.000
Z95.4 Presence of other heart-valve replacement
0.976 0.024 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.973 0.027 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.973 0.027 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.973 0.027 0.000
M20 Acquired deformities of fingers and toes
0.971 0.029 0.000
I44 Atrioventricular and left bundle-branch block
0.970 0.030 0.000
M23 Internal derangement of knee
0.969 0.031 0.000
I73 Other peripheral vascular diseases
0.966 0.034 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.964 0.036 0.000
Z88.6 Personal history of allergy to analgesic agent
0.961 0.039 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.960 0.040 0.000
I73.9 Peripheral vascular disease, unspecified
0.958 0.042 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.953 0.047 0.000
M25 Other joint disorders, not elsewhere classified
0.953 0.047 0.000
Chapter I Certain infectious and parasitic diseases
0.952 0.048 0.000
K65-K67 Diseases of peritoneum
0.952 0.048 0.000
I49 Other cardiac arrhythmias
0.946 0.054 0.000
K76 Other diseases of liver
0.940 0.060 0.000
I25.1 Atherosclerotic heart disease
0.937 0.063 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.937 0.063 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.932 0.068 0.000
I50.1 Left ventricular failure
0.931 0.069 0.000
I21.9 Acute myocardial infarction, unspecified
0.931 0.069 0.000
I50.9 Heart failure, unspecified
0.930 0.070 0.000
M20.1 Hallux valgus (acquired)
0.930 0.070 0.000
E10-E14 Diabetes mellitus
0.928 0.072 0.000
Chapter VII Diseases of the eye and adnexa
0.928 0.072 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.925 0.075 0.000
Z95.0 Presence of cardiac pacemaker
0.925 0.075 0.000
S60-S69 Injuries to the wrist and hand
0.919 0.081 0.000
K35-K38 Diseases of appendix
0.918 0.082 0.000
M25.5 Pain in joint
0.916 0.084 0.000
I20 Angina pectoris
0.916 0.084 0.000
K81 Cholecystitis
0.911 0.089 0.000
B95-B98 Bacterial, viral and other infectious agents
0.905 0.095 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.904 0.096 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.902 0.098 0.000
E10 Insulin-dependent diabetes mellitus
0.901 0.099 0.000
I44.2 Atrioventricular block, complete
0.896 0.104 0.000
K65 Peritonitis
0.895 0.105 0.000
I44.0 Atrioventricular block, first degree
0.892 0.108 0.000
I51 Complications and ill-defined descriptions of heart disease
0.891 0.109 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.891 0.109 0.000
M23.3 Other meniscus derangements
0.890 0.110 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.887 0.113 0.000
Z88.2 Personal history of allergy to sulphonamides
0.887 0.113 0.000
Z95.2 Presence of prosthetic heart valve
0.885 0.115 0.000
K75 Other inflammatory liver diseases
0.884 0.116 0.000
K81.0 Acute cholecystitis
0.883 0.117 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.880 0.120 0.000
M05-M14 Inflammatory polyarthropathies
0.872 0.128 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.869 0.131 0.000
Chapter VIII Diseases of the ear and mastoid process
0.865 0.135 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.863 0.137 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.858 0.142 0.000
H40-H42 Glaucoma
0.854 0.146 0.000
Z93 Artificial opening status
0.852 0.148 0.000
I50.0 Congestive heart failure
0.850 0.150 0.000
I49.3 Ventricular premature depolarisation
0.848 0.152 0.000
S00-S09 Injuries to the head
0.847 0.153 0.000
Z89 Acquired absence of limb
0.847 0.153 0.000
S61 Open wound of wrist and hand
0.845 0.155 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.841 0.159 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.840 0.160 0.000
K35 Acute appendicitis
0.837 0.163 0.000
I49.9 Cardiac arrhythmia, unspecified
0.834 0.166 0.000
I34 Nonrheumatic mitral valve disorders
0.834 0.166 0.000
I20.8 Other forms of angina pectoris
0.833 0.167 0.000
Z83 Family history of other specific disorders
0.831 0.169 0.000
T86 Failure and rejection of transplanted organs and tissues
0.829 0.171 0.000
Z94 Transplanted organ and tissue status
0.829 0.171 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.826 0.174 0.000
Chapter XX External causes of morbidity and mortality
0.825 0.175 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.825 0.175 0.000
H25-H28 Disorders of lens
0.824 0.176 0.000
I44.1 Atrioventricular block, second degree
0.823 0.177 0.000
E10.5 With peripheral circulatory complications
0.821 0.179 0.000
S50-S59 Injuries to the elbow and forearm
0.818 0.182 0.000
S90-S99 Injuries to the ankle and foot
0.815 0.185 0.000
I25.2 Old myocardial infarction
0.815 0.185 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.812 0.188 0.000
I74 Arterial embolism and thrombosis
0.811 0.189 0.000
M00-M03 Infectious arthropathies
0.810 0.190 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.809 0.191 0.000
K65.9 Peritonitis, unspecified
0.809 0.191 0.000
K66 Other disorders of peritoneum
0.808 0.192 0.000
I20.0 Unstable angina
0.807 0.193 0.000
I33 Acute and subacute endocarditis
0.806 0.194 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.805 0.195 0.000
S40-S49 Injuries to the shoulder and upper arm
0.802 0.198 0.000
T43.2 Other and unspecified antidepressants
0.801 0.199 0.000
H40 Glaucoma
0.801 0.199 0.000
M86-M90 Other osteopathies
0.801 0.199 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.799 0.201 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.798 0.202 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.797 0.203 0.000
M20.5 Other deformities of toe(s) (acquired)
0.797 0.203 0.000
K72 Hepatic failure, not elsewhere classified
0.796 0.203 0.000
Z80 Family history of malignant neoplasm
0.796 0.204 0.000
I25.5 Ischaemic cardiomyopathy
0.794 0.206 0.000
M24 Other specific joint derangements
0.792 0.208 0.000
I49.8 Other specified cardiac arrhythmias
0.791 0.209 0.000
I35 Nonrheumatic aortic valve disorders
0.790 0.210 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.789 0.211 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.789 0.211 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.787 0.213 0.000
M20.3 Other deformity of hallux (acquired)
0.784 0.216 0.000
M31 Other necrotising vasculopathies
0.783 0.216 0.000
I21.4 Acute subendocardial myocardial infarction
0.783 0.217 0.000
K81.9 Cholecystitis, unspecified
0.782 0.218 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.782 0.218 0.000
I05-I09 Chronic rheumatic heart diseases
0.782 0.218 0.000
Z92.0 Personal history of contraception
0.781 0.218 0.000
I30 Acute pericarditis
0.780 0.220 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.780 0.220 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.779 0.220 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.779 0.221 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.778 0.222 0.000
I45 Other conduction disorders
0.777 0.223 0.000
K65.0 Acute peritonitis
0.776 0.224 0.000
B25-B34 Other viral diseases
0.776 0.224 0.000
M23.4 Loose body in knee
0.775 0.225 0.000
M06 Other rheumatoid arthritis
0.774 0.226 0.000
Z95.3 Presence of xenogenic heart valve
0.773 0.227 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.773 0.227 0.000
Z95.1 Presence of aortocoronary bypass graft
0.771 0.229 0.000
S61.0 Open wound of finger(s) without damage to nail
0.769 0.231 0.000
M25.0 Haemarthrosis
0.768 0.232 0.000
I51.7 Cardiomegaly
0.768 0.232 0.000
K82 Other diseases of gallbladder
0.767 0.232 0.000
H26 Other cataract
0.766 0.234 0.000
E50-E64 Other nutritional deficiencies
0.765 0.235 0.000
H80-H83 Diseases of inner ear
0.765 0.235 0.000
K74 Fibrosis and cirrhosis of liver
0.764 0.236 0.000
M65-M68 Disorders of synovium and tendon
0.763 0.237 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.761 0.239 0.000
H30-H36 Disorders of choroid and retina
0.760 0.240 0.000
K76.9 Liver disease, unspecified
0.758 0.242 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.758 0.242 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.757 0.243 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.754 0.246 0.000
S80-S89 Injuries to the knee and lower leg
0.754 0.246 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.752 0.248 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.752 0.248 0.000
S70-S79 Injuries to the hip and thigh
0.749 0.251 0.000
K75.8 Other specified inflammatory liver diseases
0.748 0.252 0.000
E10.1 With ketoacidosis
0.747 0.253 0.000
E10.3 With ophthalmic complications
0.747 0.253 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.746 0.254 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.746 0.254 0.000
E16 Other disorders of pancreatic internal secretion
0.746 0.254 0.000
Z97 Presence of other devices
0.745 0.255 0.000
K37 Unspecified appendicitis
0.744 0.256 0.000
B35-B49 Mycoses
0.742 0.258 0.000
Z93.1 Gastrostomy status
0.741 0.259 0.000
Z83.5 Family history of eye and ear disorders
0.740 0.260 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.738 0.262 0.000
I22 Subsequent myocardial infarction
0.738 0.262 0.000
I42 Cardiomyopathy
0.738 0.262 0.000
A30-A49 Other bacterial diseases
0.738 0.262 0.000
I26 Pulmonary embolism
0.737 0.263 0.000
T66-T78 Other and unspecified effects of external causes
0.735 0.265 0.000
S01 Open wound of head
0.733 0.267 0.000
K81.1 Chronic cholecystitis
0.732 0.268 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.732 0.268 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.731 0.268 0.000
I51.9 Heart disease, unspecified
0.729 0.270 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.729 0.271 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.729 0.271 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.729 0.271 0.000
I34.1 Mitral (valve) prolapse
0.725 0.275 0.000
M35 Other systemic involvement of connective tissue
0.724 0.276 0.000
M25.8 Other specified joint disorders
0.723 0.277 0.000
M20.4 Other hammer toe(s) (acquired)
0.723 0.277 0.000
Chapter V Mental and behavioural disorders
0.722 0.278 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.721 0.279 0.000
Z82.3 Family history of stroke
0.721 0.279 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.720 0.280 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.720 0.280 0.000
K70 Alcoholic liver disease
0.720 0.280 0.000
E70-E90 Metabolic disorders
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M34 Systemic sclerosis
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.715 0.285 0.000
E10.4 With neurological complications
0.714 0.286 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.714 0.286 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.714 0.286 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.712 0.287 0.000
K50-K52 Noninfective enteritis and colitis
0.713 0.287 0.000
I24 Other acute ischaemic heart diseases
0.712 0.288 0.000
I20.1 Angina pectoris with documented spasm
0.711 0.289 0.000
M25.56 Pain in joint (Lower leg)
0.711 0.289 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.711 0.289 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.711 0.289 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.710 0.289 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.710 0.289 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.710 0.290 0.000
H40.9 Glaucoma, unspecified
0.709 0.291 0.000
I25.6 Silent myocardial ischaemia
0.709 0.291 0.000
I25.4 Coronary artery aneurysm
0.709 0.291 0.000
I25.3 Aneurysm of heart
0.709 0.291 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.709 0.291 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.709 0.291 0.000
S20-S29 Injuries to the thorax
0.708 0.292 0.000
Z92.9 Personal history of medical treatment, unspecified
0.707 0.293 0.000
Z92.8 Personal history of other medical treatment
0.707 0.293 0.000
Z92.5 Personal history of rehabilitation measures
0.707 0.293 0.000
Z93.2 Ileostomy status
0.706 0.294 0.000
S68 Traumatic amputation of wrist and hand
0.706 0.294 0.000
K77 Liver disorders in diseases classified elsewhere
0.705 0.295 0.000
K73 Chronic hepatitis, not elsewhere classified
0.705 0.295 0.000
K71 Toxic liver disease
0.705 0.295 0.000
H43-H45 Disorders of vitreous body and globe
0.705 0.295 0.000
K75.9 Inflammatory liver disease, unspecified
0.705 0.295 0.000
S00 Superficial injury of head
0.704 0.296 0.000
M05 Seropositive rheumatoid arthritis
0.704 0.296 0.000
Z91.5 Personal history of self-harm
0.703 0.297 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.703 0.297 0.000
I72 Other aneurysm
0.703 0.297 0.000
I70 Atherosclerosis
0.703 0.297 0.000
T79-T79 Certain early complications of trauma
0.702 0.298 0.000
Chapter XXII Codes for special purposes
0.701 0.298 0.000
H40.0 Glaucoma suspect
0.701 0.299 0.000
H81 Disorders of vestibular function
0.701 0.299 0.000
E00-E07 Disorders of thyroid gland
0.700 0.300 0.000
M21 Other acquired deformities of limbs
0.700 0.300 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.700 0.300 0.000
M25.50 Pain in joint (Multiple sites)
0.699 0.301 0.000
K75.4 Autoimmune hepatitis
0.698 0.302 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.698 0.302 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.698 0.302 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.698 0.302 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.698 0.302 0.000
Z82.2 Family history of deafness and hearing loss
0.698 0.302 0.000
Z82.1 Family history of blindness and visual loss
0.698 0.302 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.698 0.302 0.000
T87 Complications peculiar to reattachment and amputation
0.698 0.302 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.698 0.302 0.000
E40-E46 Malnutrition
0.697 0.302 0.000
Z80.3 Family history of malignant neoplasm of breast
0.697 0.303 0.000
M20.0 Deformity of finger(s)
0.696 0.304 0.000
E11 Non-insulin-dependent diabetes mellitus
0.696 0.304 0.000
I44.6 Other and unspecified fascicular block
0.696 0.304 0.000
I44.5 Left posterior fascicular block
0.696 0.304 0.000
I44.4 Left anterior fascicular block
0.696 0.304 0.000
I44.3 Other and unspecified atrioventricular block
0.696 0.304 0.000
K35.8 Acute appendicitis, other and unspecified
0.696 0.304 0.000
M23.9 Internal derangement of knee, unspecified
0.695 0.305 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.695 0.305 0.000
M23.5 Chronic instability of knee
0.695 0.305 0.000
M23.1 Discoid meniscus (congenital)
0.695 0.305 0.000
M23.0 Cystic meniscus
0.695 0.305 0.000
I31 Other diseases of pericardium
0.694 0.306 0.000
T82.1 Mechanical complication of cardiac electronic device
0.693 0.307 0.000
I73.8 Other specified peripheral vascular diseases
0.692 0.308 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.692 0.308 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.691 0.309 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.691 0.309 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.691 0.309 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.691 0.309 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.691 0.309 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.691 0.309 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.691 0.309 0.000
T36 Poisoning by systemic antibiotics
0.691 0.309 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.689 0.311 0.000
S64 Injury of nerves at wrist and hand level
0.689 0.311 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.688 0.312 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.688 0.312 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.688 0.312 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.688 0.312 0.000
T82.3 Mechanical complication of other vascular grafts
0.688 0.312 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.688 0.312 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.688 0.312 0.000
K82.8 Other specified diseases of gallbladder
0.688 0.312 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.687 0.313 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.687 0.313 0.000
H40.1 Primary open-angle glaucoma
0.686 0.314 0.000
Z89.6 Acquired absence of leg above knee
0.685 0.315 0.000
M23.8 Other internal derangements of knee
0.684 0.316 0.000
S92 Fracture of foot, except ankle
0.683 0.317 0.000
M25.9 Joint disorder, unspecified
0.683 0.317 0.000
M25.3 Other instability of joint
0.683 0.317 0.000
M25.2 Flail joint
0.683 0.317 0.000
M25.1 Fistula of joint
0.683 0.317 0.000
B99-B99 Other infectious diseases
0.683 0.317 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.683 0.317 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.683 0.317 0.000
B65-B83 Helminthiases
0.683 0.317 0.000
B50-B64 Protozoal diseases
0.683 0.317 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.683 0.317 0.000
B15-B19 Viral hepatitis
0.683 0.317 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.683 0.317 0.000
A80-A89 Viral infections of the central nervous system
0.683 0.317 0.000
A75-A79 Rickettsioses
0.683 0.317 0.000
A70-A74 Other diseases caused by chlamydiae
0.683 0.317 0.000
A65-A69 Other spirochaetal diseases
0.683 0.317 0.000
A20-A28 Certain zoonotic bacterial diseases
0.683 0.317 0.000
A15-A19 Tuberculosis
0.683 0.317 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.683 0.317 0.000
H65-H75 Diseases of middle ear and mastoid
0.682 0.318 0.000
K90-K93 Other diseases of the digestive system
0.681 0.319 0.000
H26.9 Cataract, unspecified
0.680 0.320 0.000
K76.6 Portal hypertension
0.680 0.320 0.000
E20-E35 Disorders of other endocrine glands
0.679 0.320 0.000
M25.53 Pain in joint (Forearm)
0.679 0.321 0.000
I49.2 Junctional premature depolarisation
0.678 0.322 0.000
I49.1 Atrial premature depolarisation
0.678 0.322 0.000
T86.1 Kidney transplant failure and rejection
0.678 0.322 0.000
E16.2 Hypoglycaemia, unspecified
0.678 0.322 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.677 0.323 0.000
H10-H13 Disorders of conjunctiva
0.676 0.324 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.676 0.324 0.000
M00 Pyogenic arthritis
0.675 0.324 0.000
K76.7 Hepatorenal syndrome
0.674 0.326 0.000
K76.5 Hepatic veno-occlusive disease
0.674 0.326 0.000
K76.4 Peliosis hepatis
0.674 0.326 0.000
K76.3 Infarction of liver
0.674 0.326 0.000
K76.2 Central haemorrhagic necrosis of liver
0.674 0.326 0.000
K76.1 Chronic passive congestion of liver
0.674 0.326 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.674 0.326 0.000
I27 Other pulmonary heart diseases
0.674 0.326 0.000
S67 Crushing injury of wrist and hand
0.673 0.327 0.000
Z89.5 Acquired absence of leg at or below knee
0.673 0.327 0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.672 0.327 0.000
K83 Other diseases of biliary tract
0.672 0.328 0.000
T86.0 Bone-marrow transplant rejection
0.670 0.330 0.000
I78 Diseases of capillaries
0.670 0.330 0.000
E10.9 Without complications
0.669 0.330 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.669 0.331 0.000
I71 Aortic aneurysm and dissection
0.668 0.331 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.668 0.332 0.000
I47 Paroxysmal tachycardia
0.667 0.332 0.000
I33.0 Acute and subacute infective endocarditis
0.666 0.334 0.000
E13 Other specified diabetes mellitus
0.665 0.334 0.000
E12 Malnutrition-related diabetes mellitus
0.665 0.334 0.000
M80-M85 Disorders of bone density and structure
0.665 0.334 0.000
H55-H59 Other disorders of eye and adnexa
0.665 0.335 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.665 0.335 0.000
K66.0 Peritoneal adhesions
0.665 0.335 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.663 0.337 0.000
K72.9 Hepatic failure, unspecified
0.662 0.338 0.000
M06.9 Rheumatoid arthritis, unspecified
0.660 0.340 0.000
Z94.0 Kidney transplant status
0.660 0.340 0.000
M25.4 Effusion of joint
0.659 0.340 0.000
S69 Other and unspecified injuries of wrist and hand
0.659 0.341 0.000
S65 Injury of blood vessels at wrist and hand level
0.659 0.341 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.659 0.341 0.000
S60 Superficial injury of wrist and hand
0.659 0.341 0.000
K38 Other diseases of appendix
0.658 0.341 0.000
K36 Other appendicitis
0.658 0.341 0.000
Z94.8 Other transplanted organ and tissue status
0.658 0.342 0.000
S56 Injury of muscle and tendon at forearm level
0.658 0.342 0.000
Chapter X Diseases of the respiratory system
0.658 0.342 0.000
M25.59 Pain in joint (Site unspecified)
0.657 0.343 0.000
M25.58 Pain in joint (Other)
0.657 0.343 0.000
M25.54 Pain in joint (Hand)
0.657 0.343 0.000
M25.52 Pain in joint (Upper arm)
0.657 0.343 0.000
T39.1 4-Aminophenol derivatives
0.657 0.343 0.000
M07 Psoriatic and enteropathic arthropathies
0.655 0.345 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.655 0.345 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.654 0.346 0.000
K81.8 Other cholecystitis
0.653 0.346 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.653 0.347 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.653 0.347 0.000
S01.0 Open wound of scalp
0.653 0.347 0.000
S61.8 Open wound of other parts of wrist and hand
0.653 0.347 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.652 0.348 0.000
M10 Gout
0.652 0.348 0.000
T40.2 Other opioids
0.651 0.349 0.000
W00-W19 Falls
0.650 0.350 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.649 0.351 0.000
B27 Infectious mononucleosis
0.649 0.351 0.000
T43.9 Psychotropic drug, unspecified
0.648 0.352 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.648 0.352 0.000
T43.6 Psychostimulants with abuse potential
0.648 0.352 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.648 0.352 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.648 0.352 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.648 0.352 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.648 0.352 0.000
M25.57 Pain in joint (Ankle and foot)
0.648 0.352 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.646 0.354 0.000
E10.8 With unspecified complications
0.646 0.354 0.000
E10.7 With multiple complications
0.646 0.354 0.000
E10.6 With other specified complications
0.646 0.354 0.000
E10.2 With renal complications
0.646 0.354 0.000
E10.0 With coma
0.646 0.354 0.000
I77 Other disorders of arteries and arterioles
0.646 0.354 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.646 0.354 0.000
I49.4 Other and unspecified premature depolarisation
0.645 0.354 0.000
B44 Aspergillosis
0.644 0.356 0.000
M24.1 Other articular cartilage disorders
0.644 0.356 0.000
I51.8 Other ill-defined heart diseases
0.644 0.356 0.000
I49.5 Sick sinus syndrome
0.644 0.356 0.000
K66.8 Other specified disorders of peritoneum
0.642 0.358 0.000
S80 Superficial injury of lower leg
0.642 0.358 0.000
K65.8 Other peritonitis
0.642 0.358 0.000
M40-M43 Deforming dorsopathies
0.640 0.360 0.000
I51.6 Cardiovascular disease, unspecified
0.639 0.361 0.000
I51.5 Myocardial degeneration
0.639 0.361 0.000
I51.4 Myocarditis, unspecified
0.639 0.361 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.639 0.361 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.639 0.361 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.639 0.361 0.000
I51.0 Cardiac septal defect, acquired
0.639 0.361 0.000
M06.0 Seronegative rheumatoid arthritis
0.639 0.361 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.639 0.361 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.638 0.362 0.000
M23.37 Other meniscus derangements-Capsular lig
0.638 0.362 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.638 0.362 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.638 0.362 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.638 0.362 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.638 0.362 0.000
H26.2 Complicated cataract
0.636 0.364 0.000
M25.06 Haemarthrosis (Lower leg)
0.636 0.364 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.636 0.364 0.000
M23.49 Loose body in knee-Unspec lig/men
0.635 0.365 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.635 0.365 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.635 0.365 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.634 0.366 0.000
S62 Fracture at wrist and hand level
0.634 0.366 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.634 0.366 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.633 0.366 0.000
K75.2 Nonspecific reactive hepatitis
0.633 0.366 0.000
K75.1 Phlebitis of portal vein
0.633 0.366 0.000
K75.0 Abscess of liver
0.633 0.366 0.000
Y40 Systemic antibiotics
0.633 0.367 0.000
E65-E68 Obesity and other hyperalimentation
0.633 0.367 0.000
M22 Disorders of patella
0.632 0.367 0.000
S61.1 Open wound of finger(s) with damage to nail
0.632 0.368 0.000
V80-V89 Other land transport accidents
0.631 0.369 0.000
K35.3 Acute appendicitis with localized peritonitis
0.630 0.369 0.000
M31.6 Other giant cell arteritis
0.630 0.370 0.000
M11 Other crystal arthropathies
0.627 0.372 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.627 0.373 0.000
K74.6 Other and unspecified cirrhosis of liver
0.626 0.374 0.000
I08 Multiple valve diseases
0.626 0.374 0.000
M14 Arthropathies in other diseases classified elsewhere
0.625 0.375 0.000
M12 Other specific arthropathies
0.625 0.375 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.625 0.375 0.000
M08 Juvenile arthritis
0.625 0.375 0.000
S51 Open wound of forearm
0.625 0.375 0.000
M50-M54 Other dorsopathies
0.624 0.376 0.000
I46 Cardiac arrest
0.624 0.376 0.000
H26.8 Other specified cataract
0.624 0.376 0.000
I95 Hypotension
0.624 0.376 0.000
X60-X84 Intentional self-harm
0.624 0.376 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.623 0.377 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.623 0.377 0.000
I35.0 Aortic (valve) stenosis
0.623 0.377 0.000
I30.9 Acute pericarditis, unspecified
0.623 0.377 0.000
Z89.4 Acquired absence of foot and ankle
0.623 0.377 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.622 0.378 0.000
M86 Osteomyelitis
0.620 0.380 0.000
I28 Other diseases of pulmonary vessels
0.619 0.381 0.000
Z93.3 Colostomy status
0.619 0.381 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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