TreeWAS – Variant ID: rs7223467

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H25 Senile cataract	0.000	0.000	1.000
H25.0 Senile incipient cataract	0.000	0.000	1.000
H25.1 Senile nuclear cataract	0.000	0.001	0.999
H25-H28 Disorders of lens	0.000	0.004	0.996
H26.9 Cataract, unspecified	0.000	0.005	0.995
H26 Other cataract	0.000	0.005	0.995
C18.7 Sigmoid colon	0.000	0.066	0.934
C18 Malignant neoplasm of colon	0.000	0.072	0.928
H25.9 Senile cataract, unspecified	0.000	0.073	0.927
C18.6 Descending colon	0.000	0.107	0.893
C18.5 Splenic flexure	0.000	0.136	0.864
H26.8 Other specified cataract	0.000	0.143	0.857
C18.9 Colon, unspecified	0.000	0.158	0.842
H26.0 Infantile, juvenile and presenile cataract	0.000	0.185	0.815
H26.3 Drug-induced cataract	0.000	0.217	0.783
C18.4 Transverse colon	0.000	0.231	0.769
C15-C26 Malignant neoplasms of digestive organs	0.000	0.231	0.769
C15 Malignant neoplasm of oesophagus	0.000	0.251	0.749
C18.0 Caecum	0.000	0.255	0.745
C20 Malignant neoplasm of rectum	0.000	0.262	0.738
H27 Other disorders of lens	0.000	0.265	0.735
C15.5 Lower third of oesophagus	0.000	0.270	0.730
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.000	0.275	0.725
C15.9 Oesophagus, unspecified	0.000	0.292	0.708
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.308	0.692
H26.1 Traumatic cataract	0.000	0.337	0.663
H25.2 Senile cataract, morgagnian type	0.000	0.346	0.654
C18.8 Overlapping lesion of colon	0.000	0.351	0.649
H27.0 Aphakia	0.000	0.357	0.643
H25.8 Other senile cataract	0.000	0.427	0.573
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.451	0.549
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.459	0.541
C15.8 Overlapping lesion of oesophagus	0.000	0.463	0.537
C15.2 Abdominal part of oesophagus	0.000	0.463	0.537
H28.0 Diabetic cataract	0.000	0.470	0.530
H27.9 Disorder of lens, unspecified	0.000	0.473	0.527
C18.3 Hepatic flexure	0.000	0.477	0.522
H28.8 Other disorders of lens in diseases classified elsewhere	0.000	0.480	0.519
H28.2 Cataract in other diseases classified elsewhere	0.000	0.480	0.519
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.000	0.480	0.519
H27.8 Other specified disorders of lens	0.000	0.487	0.513
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.488	0.512
C23 Malignant neoplasm of gallbladder	0.000	0.492	0.508
C15.0 Cervical part of oesophagus	0.000	0.518	0.482
C15.4 Middle third of oesophagus	0.000	0.528	0.472
C24.1 Ampulla of Vater	0.000	0.531	0.469
C15.1 Thoracic part of oesophagus	0.000	0.533	0.467
H26.4 After-cataract	0.000	0.557	0.443
C18.2 Ascending colon	0.000	0.563	0.437
C21 Malignant neoplasm of anus and anal canal	0.000	0.572	0.428
C22.0 Liver cell carcinoma	0.000	0.578	0.422
C17 Malignant neoplasm of small intestine	0.000	0.589	0.411
C18.1 Appendix	0.000	0.592	0.408
C24.8 Overlapping lesion of biliary tract	0.000	0.606	0.393
C22.7 Other specified carcinomas of liver	0.000	0.612	0.388
C22.4 Other sarcomas of liver	0.000	0.612	0.388
C22.3 Angiosarcoma of liver	0.000	0.612	0.388
C22.2 Hepatoblastoma	0.000	0.612	0.388
C22.1 Intrahepatic bile duct carcinoma	0.000	0.616	0.384
C15.3 Upper third of oesophagus	0.000	0.620	0.379
C26.8 Overlapping lesion of digestive system	0.000	0.633	0.367
C26.1 Spleen	0.000	0.633	0.367
C26.9 Ill-defined sites within the digestive system	0.000	0.646	0.354
C26.0 Intestinal tract, part unspecified	0.000	0.657	0.343
C22.9 Liver, unspecified	0.000	0.663	0.337
H27.1 Dislocation of lens	0.001	0.663	0.336
C24.9 Biliary tract, unspecified	0.000	0.666	0.334
C24.0 Extrahepatic bile duct	0.000	0.674	0.325
C17.1 Jejunum	0.000	0.685	0.315
C21.0 Anus, unspecified	0.000	0.688	0.312
C21.2 Cloacogenic zone	0.000	0.693	0.307
C17.8 Overlapping lesion of small intestine	0.000	0.705	0.295
C17.3 Meckel's diverticulum	0.000	0.705	0.295
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.705	0.295
H26.2 Complicated cataract	0.001	0.715	0.283
C17.0 Duodenum	0.000	0.743	0.257
C17.2 Ileum	0.000	0.744	0.256
C17.9 Small intestine, unspecified	0.000	0.764	0.236
C21.1 Anal canal	0.000	0.805	0.195
C16 Malignant neoplasm of stomach	0.000	0.807	0.193
C16.0 Cardia	0.000	0.846	0.154
C16.8 Overlapping lesion of stomach	0.000	0.861	0.138
C16.3 Pyloric antrum	0.000	0.865	0.134
C16.6 Greater curvature of stomach, unspecified	0.000	0.868	0.132
C16.5 Lesser curvature of stomach, unspecified	0.000	0.874	0.126
C16.4 Pylorus	0.000	0.874	0.126
C25 Malignant neoplasm of pancreas	0.000	0.885	0.115
C16.1 Fundus of stomach	0.000	0.890	0.110
S62.60 Fracture of other finger (closed)	0.107	0.893	0.000
C16.2 Body of stomach	0.000	0.896	0.104
S62.6 Fracture of other finger	0.091	0.909	0.000
C25.2 Tail of pancreas	0.000	0.915	0.085
S62.61 Fracture of other finger (open)	0.084	0.916	0.000
C25.4 Endocrine pancreas	0.000	0.918	0.082
C25.8 Overlapping lesion of pancreas	0.000	0.919	0.081
C25.7 Other parts of pancreas	0.000	0.919	0.081
C25.3 Pancreatic duct	0.000	0.930	0.070
C16.9 Stomach, unspecified	0.000	0.938	0.062
S62 Fracture at wrist and hand level	0.054	0.946	0.000
C25.9 Pancreas, unspecified	0.000	0.948	0.052
S62.2 Fracture of first metacarpal bone	0.046	0.954	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.955	0.045
S62.4 Multiple fractures of metacarpal bones	0.044	0.955	0.000
S62.7 Multiple fractures of fingers	0.044	0.956	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.957	0.043
S62.1 Fracture of other carpal bone(s)	0.043	0.957	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.957	0.043
S02.1 Fracture of base of skull	0.000	0.958	0.042
S62.0 Fracture of navicular [scaphoid] bone of hand	0.042	0.958	0.000
S02 Fracture of skull and facial bones	0.000	0.958	0.042
S62.20 Fracture of first metacarpal bone (closed)	0.041	0.959	0.000
C25.1 Body of pancreas	0.001	0.959	0.040
C25.0 Head of pancreas	0.000	0.960	0.039
S62.40 Multiple fractures of metacarpal bones (closed)	0.038	0.962	0.000
S62.71 Multiple fractures of fingers (open)	0.036	0.964	0.000
D12.3 Transverse colon	0.000	0.964	0.036
S62.10 Fracture of other carpal bone(s) (closed)	0.035	0.964	0.000
S02.3 Fracture of orbital floor	0.000	0.965	0.035
S02.7 Multiple fractures involving skull and facial bones	0.000	0.965	0.035
S02.5 Fracture of tooth	0.000	0.966	0.034
S62.70 Multiple fractures of fingers (closed)	0.034	0.966	0.000
S02.6 Fracture of mandible	0.000	0.966	0.034
S62.21 Fracture of first metacarpal bone (open)	0.033	0.967	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.033	0.967	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.033	0.967	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.032	0.968	0.000
Z90.4 Acquired absence of other parts of digestive tract	0.000	0.968	0.032
S02.0 Fracture of vault of skull	0.000	0.968	0.032
S62.11 Fracture of other carpal bone(s) (open)	0.031	0.969	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.969	0.031
S02.11 Fracture of base of skull (open)	0.000	0.970	0.030
S02.30 Fracture of orbital floor (closed)	0.000	0.970	0.030
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.970	0.030
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.030	0.970	0.000
S02.50 Fracture of tooth (closed)	0.000	0.971	0.029
S62.5 Fracture of thumb	0.029	0.971	0.000
S02.60 Fracture of mandible (closed)	0.000	0.972	0.028
S02.8 Fractures of other skull and facial bones	0.000	0.973	0.027
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.973	0.027
S62.3 Fracture of other metacarpal bone	0.026	0.974	0.000
S02.31 Fracture of orbital floor (open)	0.000	0.975	0.025
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.975	0.025
S02.51 Fracture of tooth (open)	0.000	0.975	0.025
S02.61 Fracture of mandible (open)	0.000	0.976	0.024
S02.00 Fracture of vault of skull (closed)	0.000	0.976	0.024
K50.9 Crohn's disease, unspecified	0.000	0.976	0.024
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.023	0.976	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.977	0.023
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.977	0.023
D12.8 Rectum	0.000	0.979	0.021
S62.51 Fracture of thumb (open)	0.021	0.979	0.000
Z93.2 Ileostomy status	0.000	0.979	0.021
D12.2 Ascending colon	0.000	0.979	0.021
D12.4 Descending colon	0.000	0.980	0.020
S62.31 Fracture of other metacarpal bone (open)	0.020	0.980	0.000
S02.81 Fractures of other skull and facial bones (open)	0.000	0.980	0.020
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.980	0.019
M54.39 Sciatica (Site unspecified)	0.000	0.981	0.019
D12.5 Sigmoid colon	0.000	0.981	0.019
S02.2 Fracture of nasal bones	0.000	0.982	0.018
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.017	0.983	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.983	0.017
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.983	0.016
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.983	0.017
D12.9 Anus and anal canal	0.000	0.985	0.015
K50.1 Crohn's disease of large intestine	0.000	0.985	0.015
K50.0 Crohn's disease of small intestine	0.000	0.985	0.015
S02.21 Fracture of nasal bones (open)	0.000	0.987	0.013
D12.1 Appendix	0.000	0.988	0.012
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.988	0.012
S62.50 Fracture of thumb (closed)	0.012	0.988	0.000
D12.0 Caecum	0.000	0.988	0.012
N81.4 Uterovaginal prolapse, unspecified	0.010	0.990	0.000
D12.6 Colon, unspecified	0.000	0.990	0.010
K50.8 Other Crohn's disease	0.000	0.991	0.009
D12.7 Rectosigmoid junction	0.000	0.992	0.008
M43.19 Spondylolisthesis (Site unspecified)	0.000	0.992	0.008
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.992	0.008
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.993	0.007
M43.1 Spondylolisthesis	0.000	0.993	0.007
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.993	0.007
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.994	0.006
M43.12 Spondylolisthesis (Cervical region)	0.000	0.994	0.006
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.994	0.006
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.000	0.994	0.005
M43.15 Spondylolisthesis (Thoracolumbar region)	0.000	0.994	0.005
M43.14 Spondylolisthesis (Thoracic region)	0.000	0.994	0.005
M43.13 Spondylolisthesis (Cervicothoracic region)	0.000	0.994	0.005
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.000	0.994	0.005
M43.10 Spondylolisthesis (Multiple sites in spine)	0.000	0.994	0.005
Z43.2 Attention to ileostomy	0.000	0.994	0.006
S06.8 Other intracranial injuries	0.000	0.995	0.005
H34.1 Central retinal artery occlusion	0.000	0.995	0.005
H34 Retinal vascular occlusions	0.000	0.995	0.005
H34.2 Other retinal artery occlusions	0.000	0.995	0.005
I35.2 Aortic (valve) stenosis with insufficiency	0.005	0.995	0.000
D04.7 Skin of lower limb, including hip	0.005	0.995	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
S00-S09 Injuries to the head	0.000	0.995	0.005
F40.2 Specific (isolated) phobias	0.000	0.995	0.005
S06 Intracranial injury	0.000	0.995	0.005
K51.8 Other ulcerative colitis	0.000	0.995	0.005
M54.3 Sciatica	0.000	0.995	0.005
S06.4 Epidural haemorrhage	0.000	0.995	0.005
H34.9 Retinal vascular occlusion, unspecified	0.000	0.995	0.005
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.995	0.005
H30-H36 Disorders of choroid and retina	0.000	0.995	0.005
H31 Other disorders of choroid	0.000	0.995	0.005
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.995	0.005
Chapter VII Diseases of the eye and adnexa	0.000	0.995	0.005
H36.0 Diabetic retinopathy	0.000	0.996	0.004
H31.8 Other specified disorders of choroid	0.000	0.996	0.004
H36 Retinal disorders in diseases classified elsewhere	0.000	0.996	0.004
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.004	0.996	0.000
S06.3 Focal brain injury	0.000	0.996	0.004
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.996	0.004
S62.30 Fracture of other metacarpal bone (closed)	0.004	0.996	0.001
H34.0 Transient retinal artery occlusion	0.000	0.996	0.004
M24.8 Other specific joint derangements, not elsewhere classified	0.004	0.996	0.000
M54.37 Sciatica (Lumbosacral region)	0.000	0.996	0.004
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.004	0.996	0.000
S00 Superficial injury of head	0.000	0.996	0.004
L93.0 Discoid lupus erythematosus	0.004	0.996	0.000
H31.1 Choroidal degeneration	0.000	0.996	0.004
Z98.0 Intestinal bypass and anastomosis status	0.000	0.996	0.004
S08 Traumatic amputation of part of head	0.000	0.996	0.004
S07 Crushing injury of head	0.000	0.996	0.004
S04 Injury of cranial nerves	0.000	0.996	0.004
S06.2 Diffuse brain injury	0.000	0.996	0.004
S00.8 Superficial injury of other parts of head	0.000	0.996	0.004
S06.7 Intracranial injury with prolonged coma	0.000	0.996	0.004
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.996	0.004
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.996	0.004
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.996	0.004
H31.0 Chorioretinal scars	0.000	0.996	0.004
S06.1 Traumatic cerebral oedema	0.000	0.996	0.004
M54.35 Sciatica (Thoracolumbar region)	0.000	0.996	0.004
M54.34 Sciatica-Thoracic	0.000	0.996	0.004
M54.33 Sciatica-Cervicothoracic	0.000	0.996	0.004
M54.32 Sciatica-Cervical	0.000	0.996	0.004
M54.31 Sciatica-Occipit-atl-axl	0.000	0.996	0.004
H30 Chorioretinal inflammation	0.000	0.996	0.004
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M79.60 Pain in limb (Multiple sites)	0.004	0.996	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.996	0.004
T85 Complications of other internal prosthetic devices, implants and grafts	0.004	0.996	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.996	0.003
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.000	0.996	0.003
S00.3 Superficial injury of nose	0.000	0.996	0.004
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.004	0.996	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.996	0.003
H34.8 Other retinal vascular occlusions	0.000	0.996	0.004
H31.4 Choroidal detachment	0.000	0.996	0.003
H31.2 Hereditary choroidal dystrophy	0.000	0.996	0.003
S06.9 Intracranial injury, unspecified	0.000	0.996	0.003
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.997	0.003
K29.8 Duodenitis	0.003	0.997	0.000
M54.30 Sciatica (Multiple sites in spine)	0.000	0.997	0.003
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.003	0.997	0.000
H31.3 Choroidal haemorrhage and rupture	0.000	0.997	0.003
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.003	0.997	0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.000	0.997	0.003
K63.5 Polyp of colon	0.000	0.997	0.003
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.997	0.003
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.003	0.997	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.003	0.997	0.000
K50-K52 Noninfective enteritis and colitis	0.000	0.997	0.003
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.000	0.997	0.003
H31.9 Disorder of choroid, unspecified	0.000	0.997	0.003
H55-H59 Other disorders of eye and adnexa	0.000	0.997	0.003
M43 Other deforming dorsopathies	0.000	0.997	0.003
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.003	0.997	0.000
Y41.5 Antiviral drugs	0.000	0.997	0.003
S06.5 Traumatic subdural haemorrhage	0.000	0.997	0.003
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.003	0.997	0.000
D04 Carcinoma in situ of skin	0.003	0.997	0.000
S04.9 Injury of unspecified cranial nerve	0.000	0.997	0.003
S04.8 Injury of other cranial nerves	0.000	0.997	0.003
S04.7 Injury of accessory nerve	0.000	0.997	0.003
S04.6 Injury of acoustic nerve	0.000	0.997	0.003
S04.5 Injury of facial nerve	0.000	0.997	0.003
S04.4 Injury of abducent nerve	0.000	0.997	0.003
S04.3 Injury of trigeminal nerve	0.000	0.997	0.003
S04.2 Injury of trochlear nerve	0.000	0.997	0.003
S04.1 Injury of oculomotor nerve	0.000	0.997	0.003
S04.0 Injury of optic nerve and pathways	0.000	0.997	0.003
S07.9 Crushing injury of head, part unspecified	0.000	0.997	0.003
S07.8 Crushing injury of other parts of head	0.000	0.997	0.003
S07.1 Crushing injury of skull	0.000	0.997	0.003
S07.0 Crushing injury of face	0.000	0.997	0.003
S08.9 Traumatic amputation of unspecified part of head	0.000	0.997	0.003
S08.8 Traumatic amputation of other parts of head	0.000	0.997	0.003
S08.1 Traumatic amputation of ear	0.000	0.997	0.003
S08.0 Avulsion of scalp	0.000	0.997	0.003
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.003	0.997	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.997	0.003
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.997	0.003
H30.9 Chorioretinal inflammation, unspecified	0.000	0.997	0.003
H10-H13 Disorders of conjunctiva	0.000	0.997	0.003
D04.9 Skin, unspecified	0.003	0.997	0.000
Z35 Supervision of high-risk pregnancy	0.000	0.997	0.003
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.997	0.003
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.997	0.003
S00.4 Superficial injury of ear	0.000	0.997	0.003
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.003
Y41.4 Anthelminthics	0.000	0.997	0.003
Y41.3 Other antiprotozoal drugs	0.000	0.997	0.003
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.997	0.003
Y41.0 Sulphonamides	0.000	0.997	0.003
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.997	0.003
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.997	0.003
D04.5 Skin of trunk	0.003	0.997	0.000
H30.8 Other chorioretinal inflammations	0.000	0.997	0.003
H30.2 Posterior cyclitis	0.000	0.997	0.003
H30.1 Disseminated chorioretinal inflammation	0.000	0.997	0.003
H30.0 Focal chorioretinal inflammation	0.000	0.997	0.003
S05 Injury of eye and orbit	0.000	0.997	0.003
H40-H42 Glaucoma	0.000	0.997	0.003
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.000	0.997	0.003
S00.5 Superficial injury of lip and oral cavity	0.000	0.997	0.003
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.000	0.997	0.003
S03.4 Sprain and strain of jaw	0.000	0.997	0.003
S03.3 Dislocation of other and unspecified parts of head	0.000	0.997	0.003
S03.1 Dislocation of septal cartilage of nose	0.000	0.997	0.003
S03.0 Dislocation of jaw	0.000	0.997	0.003
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.997	0.003
I05.0 Mitral stenosis	0.003	0.997	0.000
S06.0 Concussion	0.000	0.997	0.003
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.000	0.997	0.003
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
S05.8 Other injuries of eye and orbit	0.000	0.997	0.003
D04.1 Skin of eyelid, including canthus	0.003	0.997	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.997	0.003
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.997	0.003
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.997	0.003
I15.1 Hypertension secondary to other renal disorders	0.003	0.997	0.000
S00.0 Superficial injury of scalp	0.000	0.997	0.003
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.000	0.997	0.003
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
S02.20 Fracture of nasal bones (closed)	0.000	0.997	0.002
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.997	0.003
I05.9 Mitral valve disease, unspecified	0.003	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.997	0.003
S00.9 Superficial injury of head, part unspecified	0.000	0.997	0.003
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.003	0.997	0.000
I05.2 Mitral stenosis with insufficiency	0.003	0.997	0.000
Z35.8 Supervision of other high-risk pregnancies	0.000	0.997	0.003
D04.2 Skin of ear and external auricular canal	0.003	0.997	0.000
I05 Rheumatic mitral valve diseases	0.003	0.997	0.000
S00.1 Contusion of eyelid and periocular area	0.000	0.997	0.003
M24 Other specific joint derangements	0.003	0.997	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.003	0.997	0.000
S00.7 Multiple superficial injuries of head	0.000	0.997	0.003
S03.2 Dislocation of tooth	0.000	0.997	0.002
M24.2 Disorder of ligament	0.003	0.997	0.000
M43.6 Torticollis	0.000	0.997	0.002
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.997	0.003
M43.9 Deforming dorsopathy, unspecified	0.000	0.997	0.002
M43.8 Other specified deforming dorsopathies	0.000	0.997	0.002
M43.5 Other recurrent vertebral subluxation	0.000	0.997	0.002
M43.4 Other recurrent atlantoaxial subluxation	0.000	0.997	0.002
M43.3 Recurrent atlantoaxial subluxation with myelopathy	0.000	0.997	0.002
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.997	0.002
H10 Conjunctivitis	0.000	0.997	0.002
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.000	0.997	0.002
M24.6 Ankylosis of joint	0.003	0.997	0.000
M43.2 Other fusion of spine	0.000	0.997	0.002
O00.9 Ectopic pregnancy, unspecified	0.000	0.997	0.003
Q61.3 Polycystic kidney, unspecified	0.003	0.997	0.000
S05.1 Contusion of eyeball and orbital tissues	0.000	0.997	0.002
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.997	0.002
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.003	0.997	0.000
H43-H45 Disorders of vitreous body and globe	0.000	0.997	0.003
D04.8 Skin of other sites	0.002	0.997	0.000
D04.0 Skin of lip	0.002	0.997	0.000
H40.1 Primary open-angle glaucoma	0.000	0.997	0.003
K51 Ulcerative colitis	0.000	0.997	0.003
R25.2 Cramp and spasm	0.002	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
I15.9 Seconday hypertension, unspecified	0.002	0.998	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.000	0.998	0.002
M24.24 Disorder of ligament (Hand)	0.002	0.998	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.998	0.002
H10.9 Conjunctivitis, unspecified	0.000	0.998	0.002
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.002
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.998	0.002
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.998	0.002
Z35.6 Supervision of very young primigravida	0.000	0.998	0.002
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.998	0.002
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.002
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.998	0.002
M24.52 Contracture of joint (Upper arm)	0.002	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.002	0.998	0.000
M24.0 Loose body in joint	0.002	0.998	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.002	0.998	0.000
S05.7 Avulsion of eye	0.000	0.998	0.002
S05.4 Penetrating wound of orbit with or without foreign body	0.000	0.998	0.002
H42 Glaucoma in diseases classified elsewhere	0.000	0.998	0.002
M24.23 Disorder of ligament (Forearm)	0.002	0.998	0.000
M24.7 Protrusio acetabuli	0.002	0.998	0.000
I99 Other and unspecified disorders of circulatory system	0.002	0.998	0.000
S06.01 Concussion (with open intracranial wound)	0.000	0.998	0.002
M24.5 Contracture of joint	0.002	0.998	0.000
S60.2 Contusion of other parts of wrist and hand	0.002	0.998	0.000
M24.01 Loose body in joint (Shoulder region)	0.002	0.998	0.000
H10.4 Chronic conjunctivitis	0.000	0.998	0.002
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.998	0.002
S05.5 Penetrating wound of eyeball with foreign body	0.000	0.998	0.002
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.002	0.998	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.998	0.002
H35.9 Retinal disorder, unspecified	0.002	0.998	0.000
S05.9 Injury of eye and orbit, part unspecified	0.000	0.998	0.002
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.000	0.998	0.002
H58.1 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.002
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.000	0.998	0.002
J05.1 Acute epiglottitis	0.002	0.998	0.000
T85.2 Mechanical complication of intraocular lens	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.000	0.998	0.002
S60-S69 Injuries to the wrist and hand	0.002	0.998	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.998	0.002
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.998	0.002
J30.4 Allergic rhinitis, unspecified	0.000	0.998	0.002
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.998	0.002
M24.28 Disorder of ligament (Other)	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.002	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.998	0.002
I05.8 Other mitral valve diseases	0.002	0.998	0.000
K51.4 Pseudopolyposis of colon	0.000	0.998	0.002
T14.0 Superficial injury of unspecified body region	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.998	0.002
M24.64 Ankylosis of joint (Hand)	0.002	0.998	0.000
M43.62 Torticollis-Cervical	0.000	0.998	0.002
M24.9 Joint derangement, unspecified	0.002	0.998	0.000
Y43.3 Other antineoplastic drugs	0.000	0.998	0.002
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.002	0.998	0.000
S60 Superficial injury of wrist and hand	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.998	0.002
M24.29 Disorder of ligament (Site unspecified)	0.002	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.002	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.002	0.998	0.000
M43.69 Torticollis-Site unspe	0.000	0.998	0.002
M43.68 Torticollis-Sacral/sacrococ	0.000	0.998	0.002
M43.67 Torticollis-Lumbosacral	0.000	0.998	0.002
M43.66 Torticollis-Lumbar	0.000	0.998	0.002
M43.65 Torticollis-Thoracolumbar	0.000	0.998	0.002
M43.64 Torticollis-Thoracic	0.000	0.998	0.002
M43.63 Torticollis-Cervicothoracic	0.000	0.998	0.002
M43.61 Torticollis-Occipit-atl-axl	0.000	0.998	0.002
M43.60 Torticollis-Mult site	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.002	0.998	0.000
M43.39 Recurrent atlantoaxial subluxation with myelopathy (Site unspecified)	0.000	0.998	0.002
M43.38 Recurrent atlantoaxial subluxation with myelopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.37 Recurrent atlantoaxial subluxation with myelopathy (Lumbosacral region)	0.000	0.998	0.002
M43.36 Recurrent atlantoaxial subluxation with myelopathy (Lumbar region)	0.000	0.998	0.002
M43.35 Recurrent atlantoaxial subluxation with myelopathy (Thoracolumbar region)	0.000	0.998	0.002
M43.34 Recurrent atlantoaxial subluxation with myelopathy (Thoracic region)	0.000	0.998	0.002
M43.33 Recurrent atlantoaxial subluxation with myelopathy (Cervicothoracic region)	0.000	0.998	0.002
M43.32 Recurrent atlantoaxial subluxation with myelopathy (Cervical region)	0.000	0.998	0.002
M43.31 Recurrent atlantoaxial subluxation with myelopathy (Occipito-atlanto-axial region)	0.000	0.998	0.002
M43.30 Recurrent atlantoaxial subluxation with myelopathy (Multiple sites in spine)	0.000	0.998	0.002
M43.49 Other recurrent atlantoaxial subluxation-Site unspe	0.000	0.998	0.002
M43.48 Other recurrent atlantoaxial subluxation-Sacral/sacrococ	0.000	0.998	0.002
M43.47 Other recurrent atlantoaxial subluxation-Lumbosacral	0.000	0.998	0.002
M43.46 Other recurrent atlantoaxial subluxation-Lumbar	0.000	0.998	0.002
M43.45 Other recurrent atlantoaxial subluxation-Thoracolumbar	0.000	0.998	0.002
M43.44 Other recurrent atlantoaxial subluxation-Thoracic	0.000	0.998	0.002
M43.43 Other recurrent atlantoaxial subluxation-Cervicothoracic	0.000	0.998	0.002
M43.42 Other recurrent atlantoaxial subluxation-Cervical	0.000	0.998	0.002
M43.41 Other recurrent atlantoaxial subluxation-Occipit-atl-axl	0.000	0.998	0.002
M43.40 Other recurrent atlantoaxial subluxation-Mult site	0.000	0.998	0.002
M43.59 Other recurrent vertebral subluxation (Site unspecified)	0.000	0.998	0.002
M43.58 Other recurrent vertebral subluxation (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.57 Other recurrent vertebral subluxation (Lumbosacral region)	0.000	0.998	0.002
M43.56 Other recurrent vertebral subluxation (Lumbar region)	0.000	0.998	0.002
M43.55 Other recurrent vertebral subluxation (Thoracolumbar region)	0.000	0.998	0.002
M43.54 Other recurrent vertebral subluxation (Thoracic region)	0.000	0.998	0.002
M43.53 Other recurrent vertebral subluxation (Cervicothoracic region)	0.000	0.998	0.002
M43.52 Other recurrent vertebral subluxation (Cervical region)	0.000	0.998	0.002
M43.51 Other recurrent vertebral subluxation-Occipit-atl-axl	0.000	0.998	0.002
M43.50 Other recurrent vertebral subluxation (Multiple sites in spine)	0.000	0.998	0.002
M43.89 Other specified deforming dorsopathies (Site unspecified)	0.000	0.998	0.002
M43.88 Other specified deforming dorsopathies (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M43.87 Other specified deforming dorsopathies (Lumbosacral region)	0.000	0.998	0.002
M43.86 Other specified deforming dorsopathies (Lumbar region)	0.000	0.998	0.002
M43.85 Other specified deforming dorsopathies (Thoracolumbar region)	0.000	0.998	0.002
M43.84 Other specified deforming dorsopathies (Thoracic region)	0.000	0.998	0.002
M43.83 Other specified deforming dorsopathies (Cervicothoracic region)	0.000	0.998	0.002
M43.82 Other specified deforming dorsopathies (Cervical region)	0.000	0.998	0.002
M43.81 Other specified deforming dorsopathies (Occipito-atlanto-axial region)	0.000	0.998	0.002
M43.80 Other specified deforming dorsopathies (Multiple sites in spine)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations