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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72687020
log Bayes Factor = 14.6249
Chromosome 14   position 44,923,657  (GRCh37) Explore rs72687020 on Ensembl!
Variant rs72687020 is part of Cluster X0049

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I25.1 Atherosclerotic heart disease
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
I60-I69 Cerebrovascular diseases
0.997 0.003 0.000
M50-M54 Other dorsopathies
0.988 0.012 0.000
Chapter XXI Factors influencing health status and contact with health services
0.988 0.012 0.000
M54 Dorsalgia
0.984 0.016 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.983 0.017 0.000
M54.5 Low back pain
0.975 0.025 0.000
I25.2 Old myocardial infarction
0.972 0.028 0.000
I44 Atrioventricular and left bundle-branch block
0.962 0.038 0.000
I34 Nonrheumatic mitral valve disorders
0.962 0.038 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.958 0.042 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.957 0.043 0.000
Chapter VI Diseases of the nervous system
0.935 0.065 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.933 0.067 0.000
I34.0 Mitral (valve) insufficiency
0.928 0.072 0.000
I67 Other cerebrovascular diseases
0.921 0.078 0.000
O60-O75 Complications of labour and delivery
0.920 0.080 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.918 0.082 0.000
M54.59 Low back pain (Site unspecified)
0.917 0.083 0.000
M45-M49 Spondylopathies
0.915 0.085 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.912 0.088 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.910 0.090 0.000
H40-H42 Glaucoma
0.907 0.093 0.000
H43-H45 Disorders of vitreous body and globe
0.907 0.093 0.000
M05-M14 Inflammatory polyarthropathies
0.904 0.096 0.000
G40-G47 Episodic and paroxysmal disorders
0.904 0.096 0.000
I20 Angina pectoris
0.901 0.099 0.000
Z34 Supervision of normal pregnancy
0.900 0.100 0.000
Chapter I Certain infectious and parasitic diseases
0.899 0.101 0.000
M54.57 Low back pain (Lumbosacral region)
0.898 0.102 0.000
I21 Acute myocardial infarction
0.894 0.106 0.000
Z36 Antenatal screening
0.892 0.108 0.000
Z30 Contraceptive management
0.891 0.109 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.891 0.109 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.879 0.121 0.000
H30-H36 Disorders of choroid and retina
0.877 0.123 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.877 0.123 0.000
H55-H59 Other disorders of eye and adnexa
0.865 0.135 0.000
M54.56 Low back pain (Lumbar region)
0.863 0.137 0.000
M47 Spondylosis
0.863 0.137 0.000
Z35 Supervision of high-risk pregnancy
0.862 0.138 0.000
I33 Acute and subacute endocarditis
0.861 0.139 0.000
Chapter II Neoplasms
0.858 0.142 0.000
I67.9 Cerebrovascular disease, unspecified
0.857 0.143 0.000
I65.2 Occlusion and stenosis of carotid artery
0.851 0.149 0.000
M20-M25 Other joint disorders
0.851 0.149 0.000
I44.0 Atrioventricular block, first degree
0.850 0.150 0.000
H53-H54 Visual disturbances and blindness
0.849 0.151 0.000
I50 Heart failure
0.849 0.151 0.000
I10-I15 Hypertensive diseases
0.845 0.155 0.000
Chapter XXII Codes for special purposes
0.843 0.157 0.000
I44.7 Left bundle-branch block, unspecified
0.843 0.157 0.000
G40 Epilepsy
0.843 0.157 0.000
H40 Glaucoma
0.842 0.158 0.000
I05-I09 Chronic rheumatic heart diseases
0.841 0.159 0.000
I42 Cardiomyopathy
0.841 0.159 0.000
I20.0 Unstable angina
0.838 0.162 0.000
M13 Other arthritis
0.834 0.166 0.000
Chapter XX External causes of morbidity and mortality
0.832 0.168 0.000
H52 Disorders of refraction and accommodation
0.832 0.168 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.828 0.172 0.000
H43 Disorders of vitreous body
0.824 0.176 0.000
I47 Paroxysmal tachycardia
0.820 0.180 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.816 0.184 0.000
S00-S09 Injuries to the head
0.816 0.184 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.816 0.184 0.000
M54.3 Sciatica
0.813 0.187 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.812 0.188 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.810 0.190 0.000
B95-B98 Bacterial, viral and other infectious agents
0.807 0.193 0.000
G90-G99 Other disorders of the nervous system
0.806 0.194 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.802 0.198 0.000
I25.5 Ischaemic cardiomyopathy
0.801 0.199 0.000
I51 Complications and ill-defined descriptions of heart disease
0.799 0.201 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.798 0.202 0.000
Z60 Problems related to social environment
0.797 0.203 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.797 0.203 0.000
H10-H13 Disorders of conjunctiva
0.796 0.204 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.793 0.207 0.000
H40.2 Primary angle-closure glaucoma
0.789 0.211 0.000
M86-M90 Other osteopathies
0.784 0.216 0.000
L40-L45 Papulosquamous disorders
0.781 0.219 0.000
I22 Subsequent myocardial infarction
0.777 0.223 0.000
D10-D36 Benign neoplasms
0.776 0.224 0.000
M13.9 Arthritis, unspecified
0.775 0.225 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.771 0.229 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.770 0.230 0.000
M47.9 Spondylosis, unspecified
0.769 0.231 0.000
Z39 Postpartum care and examination
0.768 0.232 0.000
M47.8 Other spondylosis
0.768 0.232 0.000
Z31 Procreative management
0.767 0.233 0.000
Z30.2 Sterilisation
0.763 0.237 0.000
I61 Intracerebral haemorrhage
0.763 0.237 0.000
I33.0 Acute and subacute infective endocarditis
0.762 0.237 0.000
I44.3 Other and unspecified atrioventricular block
0.761 0.239 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.761 0.239 0.000
O00-O08 Pregnancy with abortive outcome
0.760 0.240 0.000
M54.1 Radiculopathy
0.757 0.243 0.000
D22 Melanocytic naevi
0.757 0.243 0.000
Z33 Pregnant state, incidental
0.757 0.243 0.000
M54.6 Pain in thoracic spine
0.756 0.244 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.756 0.244 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.755 0.245 0.000
S70-S79 Injuries to the hip and thigh
0.755 0.245 0.000
I44.2 Atrioventricular block, complete
0.755 0.245 0.000
I60 Subarachnoid haemorrhage
0.752 0.248 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.751 0.249 0.000
I67.2 Cerebral atherosclerosis
0.749 0.251 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.749 0.251 0.000
G40.9 Epilepsy, unspecified
0.744 0.256 0.000
M31 Other necrotising vasculopathies
0.744 0.256 0.000
M80-M85 Disorders of bone density and structure
0.743 0.257 0.000
I34.1 Mitral (valve) prolapse
0.742 0.258 0.000
I46 Cardiac arrest
0.742 0.258 0.000
I69 Sequelae of cerebrovascular disease
0.741 0.259 0.000
Z60.2 Living alone
0.738 0.262 0.000
I21.4 Acute subendocardial myocardial infarction
0.738 0.262 0.000
S01 Open wound of head
0.738 0.262 0.000
M65-M68 Disorders of synovium and tendon
0.738 0.262 0.000
I50.1 Left ventricular failure
0.737 0.263 0.000
H52.1 Myopia
0.736 0.264 0.000
H35 Other retinal disorders
0.736 0.264 0.000
C71 Malignant neoplasm of brain
0.735 0.265 0.000
Z34.0 Supervision of normal first pregnancy
0.735 0.265 0.000
I10 Essential (primary) hypertension
0.734 0.266 0.000
G20-G26 Extrapyramidal and movement disorders
0.734 0.266 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.733 0.267 0.000
H33 Retinal detachments and breaks
0.732 0.268 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.731 0.269 0.000
M54.2 Cervicalgia
0.731 0.269 0.000
G43 Migraine
0.730 0.270 0.000
Z35.5 Supervision of elderly primigravida
0.730 0.270 0.000
H57 Other disorders of eye and adnexa
0.728 0.272 0.000
M40-M43 Deforming dorsopathies
0.727 0.273 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.724 0.276 0.000
Z36.9 Antenatal screening, unspecified
0.723 0.277 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.721 0.278 0.000
D18 Haemangioma and lymphangioma, any site
0.721 0.279 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.719 0.281 0.000
L20-L30 Dermatitis and eczema
0.718 0.282 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.283 0.000
M91-M94 Chondropathies
0.716 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
I38 Endocarditis, valve unspecified
0.716 0.284 0.000
A00-A09 Intestinal infectious diseases
0.716 0.284 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.715 0.285 0.000
H53 Visual disturbances
0.715 0.285 0.000
A30-A49 Other bacterial diseases
0.715 0.285 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.715 0.285 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.715 0.285 0.000
I62 Other nontraumatic intracranial haemorrhage
0.715 0.285 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.713 0.287 0.000
I47.2 Ventricular tachycardia
0.713 0.287 0.000
O63 Long labour
0.712 0.288 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.712 0.288 0.000
Z36.8 Other antenatal screening
0.712 0.288 0.000
I08 Multiple valve diseases
0.711 0.289 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.709 0.291 0.000
M53 Other dorsopathies, not elsewhere classified
0.708 0.292 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.708 0.292 0.000
Chapter VIII Diseases of the ear and mastoid process
0.707 0.293 0.000
I20.8 Other forms of angina pectoris
0.707 0.293 0.000
M54.8 Other dorsalgia
0.705 0.295 0.000
M54.4 Lumbago with sciatica
0.705 0.295 0.000
M54.0 Panniculitis affecting regions of neck and back
0.705 0.295 0.000
Z38 Liveborn infants according to place of birth
0.705 0.295 0.000
Z32 Pregnancy examination and test
0.705 0.295 0.000
H44 Disorders of globe
0.703 0.297 0.000
S20-S29 Injuries to the thorax
0.703 0.297 0.000
H50 Other strabismus
0.702 0.298 0.000
M50 Cervical disk disorders
0.702 0.298 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.702 0.298 0.000
I35 Nonrheumatic aortic valve disorders
0.701 0.299 0.000
H43.3 Other vitreous opacities
0.700 0.300 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.700 0.300 0.000
M54.9 Dorsalgia, unspecified
0.700 0.300 0.000
I44.1 Atrioventricular block, second degree
0.699 0.301 0.000
M54.55 Low back pain (Thoracolumbar region)
0.699 0.301 0.000
M54.54 Low back pain-Thoracic
0.699 0.301 0.000
M54.53 Low back pain-Cervicothoracic
0.699 0.301 0.000
M54.52 Low back pain-Cervical
0.699 0.301 0.000
M54.51 Low back pain-Occipit-atl-axl
0.699 0.301 0.000
M54.50 Low back pain (Multiple sites in spine)
0.699 0.301 0.000
T66-T78 Other and unspecified effects of external causes
0.699 0.301 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.698 0.302 0.000
M07 Psoriatic and enteropathic arthropathies
0.697 0.303 0.000
Z22 Carrier of infectious disease
0.697 0.303 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.691 0.309 0.000
H43.1 Vitreous haemorrhage
0.690 0.310 0.000
I44.6 Other and unspecified fascicular block
0.690 0.310 0.000
I44.5 Left posterior fascicular block
0.690 0.310 0.000
I44.4 Left anterior fascicular block
0.690 0.310 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.689 0.311 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.689 0.311 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.689 0.311 0.000
L60-L75 Disorders of skin appendages
0.689 0.311 0.000
I42.9 Cardiomyopathy, unspecified
0.689 0.311 0.000
O62 Abnormalities of forces of labour
0.688 0.312 0.000
M54.39 Sciatica (Site unspecified)
0.687 0.313 0.000
O85-O92 Complications predominantly related to the puerperium
0.687 0.313 0.000
M05 Seropositive rheumatoid arthritis
0.687 0.313 0.000
I51.8 Other ill-defined heart diseases
0.686 0.314 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.685 0.315 0.000
I31 Other diseases of pericardium
0.684 0.316 0.000
I74 Arterial embolism and thrombosis
0.684 0.316 0.000
I63 Cerebral infarction
0.684 0.316 0.000
H52.0 Hypermetropia
0.683 0.317 0.000
H40.0 Glaucoma suspect
0.683 0.317 0.000
Chapter X Diseases of the respiratory system
0.682 0.318 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.681 0.319 0.000
D18.0 Haemangioma, any site
0.681 0.319 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.679 0.321 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.677 0.323 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.677 0.323 0.000
M70-M79 Other soft tissue disorders
0.677 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.676 0.324 0.000
I20.1 Angina pectoris with documented spasm
0.676 0.324 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.675 0.325 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.673 0.327 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.673 0.327 0.000
H36 Retinal disorders in diseases classified elsewhere
0.672 0.328 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.672 0.328 0.000
M23 Internal derangement of knee
0.671 0.329 0.000
Y00-Y09 Assault
0.671 0.329 0.000
S01.0 Open wound of scalp
0.671 0.329 0.000
G70-G73 Diseases of myoneural junction and muscle
0.670 0.330 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.670 0.330 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.670 0.330 0.000
L40 Psoriasis
0.670 0.330 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.670 0.330 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.670 0.330 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.669 0.331 0.000
G30-G32 Other degenerative diseases of the nervous system
0.668 0.332 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.666 0.334 0.000
M48 Other spondylopathies
0.664 0.336 0.000
I42.0 Dilated cardiomyopathy
0.663 0.337 0.000
S50-S59 Injuries to the elbow and forearm
0.663 0.337 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.662 0.338 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.661 0.339 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.661 0.339 0.000
I67.5 Moyamoya disease
0.661 0.339 0.000
I67.4 Hypertensive encephalopathy
0.661 0.339 0.000
I67.3 Progressive vascular leukoencephalopathy
0.661 0.339 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.661 0.339 0.000
O72 Postpartum haemorrhage
0.659 0.340 0.000
O74 Complications of anaesthesia during labour and delivery
0.659 0.341 0.000
O73 Retained placenta and membranes, without haemorrhage
0.659 0.341 0.000
O71 Other obstetric trauma
0.659 0.341 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.659 0.341 0.000
O66 Other obstructed labour
0.659 0.341 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.659 0.341 0.000
O61 Failed induction of labour
0.659 0.341 0.000
O60 Preterm delivery
0.659 0.341 0.000
H54 Blindness and low vision
0.659 0.341 0.000
H40.5 Glaucoma secondary to other eye disorders
0.658 0.341 0.000
T79-T79 Certain early complications of trauma
0.658 0.342 0.000
T33-T35 Frostbite
0.658 0.342 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.658 0.342 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.658 0.342 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.658 0.342 0.000
T00-T07 Injuries involving multiple body regions
0.658 0.342 0.000
S90-S99 Injuries to the ankle and foot
0.658 0.342 0.000
S10-S19 Injuries to the neck
0.658 0.342 0.000
O80-O84 Delivery
0.658 0.342 0.000
S60-S69 Injuries to the wrist and hand
0.658 0.342 0.000
M22 Disorders of patella
0.657 0.343 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.657 0.343 0.000
M15-M19 Arthrosis
0.656 0.344 0.000
M49 Spondylopathies in diseases classified elsewhere
0.656 0.344 0.000
H33.3 Retinal breaks without detachment
0.655 0.345 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.654 0.346 0.000
L50-L54 Urticaria and erythema
0.654 0.346 0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.654 0.346 0.000
I65.8 Occlusion and stenosis of other precerebral artery
0.654 0.346 0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.654 0.346 0.000
I65.1 Occlusion and stenosis of basilar artery
0.654 0.346 0.000
I65.0 Occlusion and stenosis of vertebral artery
0.654 0.346 0.000
H51 Other disorders of binocular movement
0.652 0.348 0.000
H49 Paralytic strabismus
0.652 0.348 0.000
M46 Other inflammatory spondylopathies
0.652 0.348 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.651 0.349 0.000
H11 Other disorders of conjunctiva
0.651 0.349 0.000
G95 Other diseases of spinal cord
0.650 0.349 0.000
H42 Glaucoma in diseases classified elsewhere
0.650 0.350 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.650 0.350 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.649 0.351 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.649 0.351 0.000
M14 Arthropathies in other diseases classified elsewhere
0.648 0.352 0.000
M12 Other specific arthropathies
0.648 0.352 0.000
M11 Other crystal arthropathies
0.648 0.352 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.648 0.352 0.000
M08 Juvenile arthritis
0.648 0.352 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.648 0.352 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.648 0.352 0.000
G41 Status epilepticus
0.648 0.352 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.648 0.352 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.648 0.352 0.000
H46 Optic neuritis
0.646 0.354 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.646 0.354 0.000
C51-C58 Malignant neoplasms of female genital organs
0.645 0.355 0.000
Z57 Occupational exposure to risk-factors
0.645 0.355 0.000
B99-B99 Other infectious diseases
0.644 0.356 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.644 0.356 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.644 0.356 0.000
B65-B83 Helminthiases
0.644 0.356 0.000
B50-B64 Protozoal diseases
0.644 0.356 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.644 0.356 0.000
B15-B19 Viral hepatitis
0.644 0.356 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.644 0.356 0.000
A80-A89 Viral infections of the central nervous system
0.644 0.356 0.000
A75-A79 Rickettsioses
0.644 0.356 0.000
A70-A74 Other diseases caused by chlamydiae
0.644 0.356 0.000
A65-A69 Other spirochaetal diseases
0.644 0.356 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.644 0.356 0.000
A20-A28 Certain zoonotic bacterial diseases
0.644 0.356 0.000
A15-A19 Tuberculosis
0.644 0.356 0.000
H18 Other disorders of cornea
0.644 0.356 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.643 0.357 0.000
C71.2 Temporal lobe
0.643 0.357 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.641 0.359 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.641 0.359 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.641 0.359 0.000
C69 Malignant neoplasm of eye and adnexa
0.641 0.359 0.000
Z36.5 Antenatal screening for isoimmunisation
0.640 0.360 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.640 0.360 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.640 0.360 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.640 0.360 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.640 0.360 0.000
M25 Other joint disorders, not elsewhere classified
0.639 0.361 0.000
Z30.9 Contraceptive management, unspecified
0.639 0.361 0.000
Z30.8 Other contraceptive management
0.639 0.361 0.000
Z30.4 Surveillance of contraceptive drugs
0.639 0.361 0.000
Z30.3 Menstrual extraction
0.639 0.361 0.000
Z30.0 General counselling and advice on contraception
0.639 0.361 0.000
L10-L14 Bullous disorders
0.639 0.361 0.000
S72 Fracture of femur
0.638 0.362 0.000
A49 Bacterial infection of unspecified site
0.638 0.362 0.000
I67.8 Other specified cerebrovascular diseases
0.638 0.362 0.000
D23 Other benign neoplasms of skin
0.637 0.363 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.636 0.363 0.000
I50.9 Heart failure, unspecified
0.636 0.364 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.636 0.364 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.636 0.364 0.000
C71.9 Brain, unspecified
0.635 0.365 0.000
I70 Atherosclerosis
0.635 0.365 0.000
G96 Other disorders of central nervous system
0.635 0.365 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.634 0.366 0.000
G45.3 Amaurosis fugax
0.634 0.366 0.000
O36 Maternal care for other known or suspected foetal problems
0.633 0.367 0.000
I05 Rheumatic mitral valve diseases
0.633 0.367 0.000
I71 Aortic aneurysm and dissection
0.633 0.367 0.000
T92 Sequelae of injuries of upper limb
0.632 0.368 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.632 0.368 0.000
M13.0 Polyarthritis, unspecified
0.632 0.368 0.000
H43.8 Other disorders of vitreous body
0.632 0.368 0.000
G44 Other headache syndromes
0.631 0.368 0.000
Z65 Problems related to other psychosocial circumstances
0.630 0.369 0.000
Z64 Problems related to certain psychosocial circumstances
0.630 0.369 0.000
Z63 Other problems related to primary support group, including family circumstances
0.630 0.369 0.000
Z62 Other problems related to upbringing
0.630 0.369 0.000
Z61 Problems related to negative life events in childhood
0.630 0.369 0.000
Z59 Problems related to housing and economic circumstances
0.630 0.369 0.000
Z58 Problems related to physical environment
0.630 0.369 0.000
Z56 Problems related to employment and unemployment
0.630 0.369 0.000
Z55 Problems related to education and literacy
0.630 0.369 0.000
V10-V19 Pedal cyclist injured in transport accident
0.630 0.370 0.000
B35-B49 Mycoses
0.630 0.370 0.000
H53.8 Other visual disturbances
0.630 0.370 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.629 0.371 0.000
H31 Other disorders of choroid
0.629 0.371 0.000
H30 Chorioretinal inflammation
0.629 0.371 0.000
Y86 Sequelae of other accidents
0.629 0.371 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.627 0.373 0.000
G45.4 Transient global amnesia
0.626 0.374 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.625 0.375 0.000
Chapter V Mental and behavioural disorders
0.625 0.375 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.625 0.375 0.000
H20 Iridocyclitis
0.625 0.375 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.625 0.375 0.000
Z29 Need for other prophylactic measures
0.624 0.376 0.000
M24 Other specific joint derangements
0.623 0.377 0.000
L43 Lichen planus
0.623 0.377 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.621 0.379 0.000
Z34.8 Supervision of other normal pregnancy
0.621 0.379 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.620 0.379 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.620 0.379 0.000
I21.9 Acute myocardial infarction, unspecified
0.620 0.380 0.000
G93 Other disorders of brain
0.619 0.381 0.000
O41 Other disorders of amniotic fluid and membranes
0.619 0.381 0.000
M47.2 Other spondylosis with radiculopathy
0.619 0.381 0.000
M47.1 Other spondylosis with myelopathy
0.619 0.381 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.619 0.381 0.000
Z35.9 Supervision of high-risk pregnancy, unspecified
0.618 0.382 0.000
Z35.8 Supervision of other high-risk pregnancies
0.618 0.382 0.000
Z35.7 Supervision of high-risk pregnancy due to social problems
0.618 0.382 0.000
Z35.6 Supervision of very young primigravida
0.618 0.382 0.000
Z35.4 Supervision of pregnancy with grand multiparity
0.618 0.382 0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care
0.618 0.382 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.618 0.382 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.618 0.382 0.000
I33.9 Acute endocarditis, unspecified
0.617 0.382 0.000
H55 Nystagmus and other irregular eye movements
0.617 0.383 0.000
M86 Osteomyelitis
0.617 0.383 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.617 0.383 0.000
I67.1 Cerebral aneurysm, nonruptured
0.617 0.383 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.617 0.383 0.000
C15-C26 Malignant neoplasms of digestive organs
0.616 0.384 0.000
H35.5 Hereditary retinal dystrophy
0.616 0.384 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.616 0.384 0.000
X60-X84 Intentional self-harm
0.616 0.384 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.615 0.384 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.615 0.384 0.000
C64-C68 Malignant neoplasms of urinary tract
0.614 0.386 0.000
Z39.0 Care and examination immediately after delivery
0.613 0.387 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.613 0.387 0.000
Z31.0 Tuboplasty or vasoplasty after previous sterilisation
0.612 0.387 0.000
I78 Diseases of capillaries
0.612 0.388 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.612 0.388 0.000
H52.2 Astigmatism
0.612 0.388 0.000
D30 Benign neoplasm of urinary organs
0.611 0.389 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.610 0.390 0.000
M34 Systemic sclerosis
0.610 0.390 0.000
M33 Dermatopolymyositis
0.610 0.390 0.000
M32 Systemic lupus erythematosus
0.610 0.390 0.000
M30 Polyarteritis nodosa and related conditions
0.610 0.390 0.000
M21 Other acquired deformities of limbs
0.610 0.390 0.000
M31.6 Other giant cell arteritis
0.610 0.390 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.609 0.391 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.609 0.391 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.608 0.391 0.000
D22.0 Melanocytic naevi of lip
0.608 0.391 0.000
M87 Osteonecrosis
0.607 0.392 0.000
G91 Hydrocephalus
0.607 0.392 0.000
R07 Pain in throat and chest
0.607 0.393 0.000
S00 Superficial injury of head
0.606 0.394 0.000
I15 Secondary hypertension
0.606 0.394 0.000
I13 Hypertensive heart and renal disease
0.606 0.394 0.000
I11 Hypertensive heart disease
0.606 0.394 0.000
A08 Viral and other specified intestinal infections
0.606 0.394 0.000
M13.98 Arthritis, unspecified (Other)
0.606 0.394 0.000
I12 Hypertensive renal disease
0.606 0.394 0.000
J09-J18 Influenza and pneumonia
0.606 0.394 0.000
G43.9 Migraine, unspecified
0.605 0.395 0.000
G20 Parkinson's disease
0.605 0.395 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.604 0.396 0.000
G40.8 Other epilepsy
0.604 0.396 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.604 0.396 0.000
G40.5 Special epileptic syndromes
0.604 0.396 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.604 0.396 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.604 0.396 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.604 0.396 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.604 0.396 0.000
H40.8 Other glaucoma
0.604 0.396 0.000
H40.6 Glaucoma secondary to drugs
0.604 0.396 0.000
H40.4 Glaucoma secondary to eye inflammation
0.604 0.396 0.000
H40.3 Glaucoma secondary to eye trauma
0.604 0.396 0.000
M45 Ankylosing spondylitis
0.603 0.397 0.000
I09 Other rheumatic heart diseases
0.603 0.397 0.000
I07 Rheumatic tricuspid valve diseases
0.603 0.397 0.000
I06 Rheumatic aortic valve diseases
0.603 0.397 0.000
I42.8 Other cardiomyopathies
0.603 0.397 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.603 0.397 0.000
I42.6 Alcoholic cardiomyopathy
0.603 0.397 0.000
I42.5 Other restrictive cardiomyopathy
0.603 0.397 0.000
I42.4 Endocardial fibroelastosis
0.603 0.397 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.603 0.397 0.000
I42.2 Other hypertrophic cardiomyopathy
0.603 0.397 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.603 0.397 0.000
D11 Benign neoplasm of major salivary glands
0.603 0.397 0.000
O02 Other abnormal products of conception
0.602 0.398 0.000
I24 Other acute ischaemic heart diseases
0.601 0.398 0.000
M06 Other rheumatoid arthritis
0.601 0.399 0.000
B25-B34 Other viral diseases
0.601 0.399 0.000
M10 Gout
0.599 0.401 0.000
M13.8 Other specified arthritis
0.598 0.402 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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