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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72687965
log Bayes Factor = 17.5275
Chromosome 1   position 114,073,152  (GRCh37) Explore rs72687965 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
E03 Other hypothyroidism
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.999 0.001 0.000
E10.9 Without complications
0.998 0.002 0.000
E11 Non-insulin-dependent diabetes mellitus
0.996 0.004 0.000
M70-M79 Other soft tissue disorders
0.989 0.011 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.989 0.011 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.987 0.013 0.000
O60-O75 Complications of labour and delivery
0.984 0.016 0.000
I73 Other peripheral vascular diseases
0.984 0.016 0.000
Chapter XXI Factors influencing health status and contact with health services
0.980 0.020 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.978 0.022 0.000
M75 Shoulder lesions
0.976 0.024 0.000
E11.9 Without complications
0.976 0.024 0.000
I20-I25 Ischaemic heart diseases
0.970 0.030 0.000
I73.9 Peripheral vascular disease, unspecified
0.967 0.033 0.000
Z36 Antenatal screening
0.964 0.036 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.951 0.049 0.000
I74 Arterial embolism and thrombosis
0.950 0.050 0.000
I25 Chronic ischaemic heart disease
0.950 0.050 0.000
M75.1 Rotator cuff syndrome
0.940 0.060 0.000
O72 Postpartum haemorrhage
0.938 0.062 0.000
I25.2 Old myocardial infarction
0.935 0.065 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.931 0.069 0.000
O85-O92 Complications predominantly related to the puerperium
0.930 0.070 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.930 0.070 0.000
O48 Prolonged pregnancy
0.927 0.073 0.000
I71 Aortic aneurysm and dissection
0.927 0.073 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.925 0.075 0.000
I30-I52 Other forms of heart disease
0.923 0.077 0.000
E11.5 With peripheral circulatory complications
0.914 0.086 0.000
O72.1 Other immediate postpartum haemorrhage
0.909 0.091 0.000
Z34 Supervision of normal pregnancy
0.907 0.093 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.906 0.094 0.000
Z60 Problems related to social environment
0.906 0.094 0.000
I51 Complications and ill-defined descriptions of heart disease
0.905 0.095 0.000
Z35 Supervision of high-risk pregnancy
0.905 0.095 0.000
Z60.2 Living alone
0.892 0.108 0.000
I21 Acute myocardial infarction
0.892 0.108 0.000
M72 Fibroblastic disorders
0.891 0.109 0.000
E10.2 With renal complications
0.891 0.109 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.888 0.112 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.879 0.121 0.000
E11.4 With neurological complications
0.877 0.123 0.000
M40-M43 Deforming dorsopathies
0.874 0.126 0.000
M75.4 Impingement syndrome of shoulder
0.874 0.126 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.872 0.128 0.000
E10.5 With peripheral circulatory complications
0.871 0.129 0.000
I51.9 Heart disease, unspecified
0.866 0.134 0.000
M75.5 Bursitis of shoulder
0.866 0.134 0.000
M05 Seropositive rheumatoid arthritis
0.862 0.138 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.861 0.139 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.852 0.148 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.849 0.151 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.848 0.152 0.000
E10.4 With neurological complications
0.847 0.153 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.847 0.153 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.845 0.155 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.845 0.155 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.844 0.156 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.843 0.157 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.842 0.157 0.000
O42 Premature rupture of membranes
0.837 0.163 0.000
O40 Polyhydramnios
0.835 0.165 0.000
Z32 Pregnancy examination and test
0.833 0.167 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.831 0.169 0.000
Z34.8 Supervision of other normal pregnancy
0.829 0.171 0.000
I74.5 Embolism and thrombosis of iliac artery
0.827 0.173 0.000
O74 Complications of anaesthesia during labour and delivery
0.822 0.178 0.000
Z36.8 Other antenatal screening
0.821 0.179 0.000
O71 Other obstetric trauma
0.821 0.179 0.000
I77 Other disorders of arteries and arterioles
0.820 0.180 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.817 0.182 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.817 0.183 0.000
E10.1 With ketoacidosis
0.815 0.185 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.814 0.186 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.814 0.186 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.813 0.187 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.813 0.187 0.000
M65-M68 Disorders of synovium and tendon
0.811 0.189 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.811 0.189 0.000
I73.0 Raynaud's syndrome
0.809 0.191 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.808 0.192 0.000
L20-L30 Dermatitis and eczema
0.806 0.194 0.000
M06.3 Rheumatoid nodule
0.804 0.196 0.000
E13 Other specified diabetes mellitus
0.804 0.196 0.000
I25.5 Ischaemic cardiomyopathy
0.802 0.198 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.802 0.198 0.000
D73 Diseases of spleen
0.800 0.200 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.800 0.200 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.799 0.201 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.799 0.201 0.000
O86 Other puerperal infections
0.797 0.203 0.000
E65-E68 Obesity and other hyperalimentation
0.795 0.205 0.000
I46 Cardiac arrest
0.795 0.205 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.794 0.206 0.000
I23 Certain current complications following acute myocardial infarction
0.793 0.207 0.000
O62 Abnormalities of forces of labour
0.793 0.207 0.000
Q80-Q89 Other congenital malformations
0.792 0.208 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.791 0.209 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.789 0.211 0.000
O24 Diabetes mellitus in pregnancy
0.789 0.211 0.000
Z33 Pregnant state, incidental
0.787 0.213 0.000
E10.8 With unspecified complications
0.787 0.213 0.000
O87 Venous complications in the puerperium
0.786 0.214 0.000
E07 Other disorders of thyroid
0.785 0.215 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.785 0.215 0.000
M76 Enthesopathies of lower limb, excluding foot
0.784 0.216 0.000
M60-M63 Disorders of muscles
0.784 0.216 0.000
I42 Cardiomyopathy
0.784 0.216 0.000
M86-M90 Other osteopathies
0.783 0.217 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.783 0.217 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.779 0.221 0.000
I49 Other cardiac arrhythmias
0.776 0.224 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.772 0.228 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.772 0.228 0.000
Q50-Q56 Congenital malformations of genital organs
0.772 0.228 0.000
I21.9 Acute myocardial infarction, unspecified
0.768 0.232 0.000
M91-M94 Chondropathies
0.768 0.232 0.000
I31 Other diseases of pericardium
0.768 0.232 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.766 0.234 0.000
E11.2 With renal complications
0.766 0.234 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.766 0.234 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.764 0.236 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.763 0.237 0.000
Z29 Need for other prophylactic measures
0.761 0.239 0.000
Chapter XXII Codes for special purposes
0.760 0.240 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.759 0.241 0.000
I51.7 Cardiomegaly
0.758 0.242 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.757 0.243 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.756 0.244 0.000
M71 Other bursopathies
0.756 0.244 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.756 0.244 0.000
O26.9 Pregnancy-related condition, unspecified
0.755 0.245 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.755 0.245 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.754 0.246 0.000
D73.0 Hyposplenism
0.754 0.246 0.000
E10.3 With ophthalmic complications
0.750 0.250 0.000
O85 Puerperal sepsis
0.748 0.252 0.000
O44 Placenta praevia
0.747 0.253 0.000
I77.1 Stricture of artery
0.746 0.254 0.000
E11.1 With ketoacidosis
0.745 0.255 0.000
O26.8 Other specified pregnancy-related conditions
0.745 0.255 0.000
M41 Scoliosis
0.743 0.257 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.741 0.259 0.000
D50-D53 Nutritional anaemias
0.741 0.259 0.000
O46.9 Antepartum haemorrhage, unspecified
0.741 0.259 0.000
M14 Arthropathies in other diseases classified elsewhere
0.740 0.260 0.000
D55-D59 Haemolytic anaemias
0.739 0.261 0.000
I42.0 Dilated cardiomyopathy
0.738 0.262 0.000
O72.0 Third-stage haemorrhage
0.737 0.263 0.000
O43 Placental disorders
0.736 0.264 0.000
Z39 Postpartum care and examination
0.735 0.265 0.000
I72 Other aneurysm
0.735 0.265 0.000
L27 Dermatitis due to substances taken internally
0.733 0.267 0.000
O23 Infections of genito-urinary tract in pregnancy
0.732 0.268 0.000
M75.9 Shoulder lesion, unspecified
0.731 0.269 0.000
M06.0 Seronegative rheumatoid arthritis
0.731 0.269 0.000
Z32.0 Pregnancy, not (yet) confirmed
0.730 0.270 0.000
Z34.0 Supervision of normal first pregnancy
0.729 0.271 0.000
I25.1 Atherosclerotic heart disease
0.727 0.273 0.000
E11.6 With other specified complications
0.723 0.277 0.000
Chapter XX External causes of morbidity and mortality
0.720 0.280 0.000
M00-M03 Infectious arthropathies
0.719 0.281 0.000
I51.4 Myocarditis, unspecified
0.719 0.281 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E10.0 With coma
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.4 Inflammatory polyarthropathy
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
E03.8 Other specified hypothyroidism
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.716 0.284 0.000
E00 Congenital iodine-deficiency syndrome
0.716 0.284 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.716 0.284 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.715 0.285 0.000
E11.8 With unspecified complications
0.714 0.286 0.000
E11.7 With multiple complications
0.714 0.286 0.000
E11.0 With coma
0.714 0.286 0.000
O30 Multiple gestation
0.713 0.287 0.000
D68 Other coagulation defects
0.710 0.290 0.000
O28 Abnormal findings on antenatal screening of mother
0.710 0.290 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.709 0.291 0.000
T66-T78 Other and unspecified effects of external causes
0.708 0.292 0.000
O45 Premature separation of placenta [abruptio placentae]
0.707 0.292 0.000
O33 Maternal care for known or suspected disproportion
0.707 0.292 0.000
O31 Complications specific to multiple gestation
0.707 0.292 0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery
0.707 0.293 0.000
E06 Thyroiditis
0.706 0.294 0.000
M07 Psoriatic and enteropathic arthropathies
0.706 0.294 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.705 0.294 0.000
O60 Preterm delivery
0.705 0.294 0.000
I73.8 Other specified peripheral vascular diseases
0.705 0.295 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.705 0.295 0.000
M43 Other deforming dorsopathies
0.705 0.295 0.000
O61 Failed induction of labour
0.704 0.296 0.000
O34.1 Maternal care for tumour of corpus uteri
0.703 0.297 0.000
Q23 Congenital malformations of aortic and mitral valves
0.701 0.299 0.000
Z38 Liveborn infants according to place of birth
0.701 0.299 0.000
I37 Pulmonary valve disorders
0.701 0.299 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.701 0.299 0.000
M75.8 Other shoulder lesions
0.700 0.300 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.699 0.301 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.698 0.302 0.000
I51.8 Other ill-defined heart diseases
0.697 0.303 0.000
M77 Other enthesopathies
0.694 0.306 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.692 0.308 0.000
Z36.5 Antenatal screening for isoimmunisation
0.691 0.309 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.691 0.309 0.000
M75.3 Calcific tendinitis of shoulder
0.689 0.311 0.000
I38 Endocarditis, valve unspecified
0.689 0.311 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.688 0.312 0.000
I70 Atherosclerosis
0.688 0.312 0.000
I10-I15 Hypertensive diseases
0.688 0.312 0.000
D80-D89 Certain disorders involving the immune mechanism
0.687 0.313 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.685 0.315 0.000
O63 Long labour
0.685 0.315 0.000
O36 Maternal care for other known or suspected foetal problems
0.683 0.317 0.000
O87.2 Haemorrhoids in the puerperium
0.683 0.317 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.682 0.318 0.000
Q35-Q37 Cleft lip and cleft palate
0.682 0.318 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.682 0.318 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.681 0.319 0.000
I74.8 Embolism and thrombosis of other arteries
0.681 0.319 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.681 0.319 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.681 0.319 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.681 0.319 0.000
I25.6 Silent myocardial ischaemia
0.681 0.319 0.000
I25.4 Coronary artery aneurysm
0.681 0.319 0.000
M65 Synovitis and tenosynovitis
0.681 0.319 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.680 0.320 0.000
I71.0 Dissection of aorta [any part]
0.680 0.320 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.678 0.322 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.678 0.322 0.000
Z29.8 Other specified prophylactic measures
0.677 0.323 0.000
L30 Other dermatitis
0.676 0.324 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.675 0.325 0.000
I24 Other acute ischaemic heart diseases
0.673 0.327 0.000
O72.3 Postpartum coagulation defects
0.672 0.327 0.000
D51 Vitamin B12 deficiency anaemia
0.669 0.331 0.000
O86.0 Infection of obstetric surgical wound
0.669 0.331 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.668 0.332 0.000
O29 Complications of anaesthesia during pregnancy
0.667 0.333 0.000
O22 Venous complications in pregnancy
0.667 0.333 0.000
O25 Malnutrition in pregnancy
0.667 0.333 0.000
O90 Complications of the puerperium, not elsewhere classified
0.667 0.333 0.000
L80 Vitiligo
0.667 0.333 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.667 0.333 0.000
O91 Infections of breast associated with childbirth
0.667 0.333 0.000
O89 Complications of anaesthesia during the puerperium
0.667 0.333 0.000
O88 Obstetric embolism
0.667 0.333 0.000
I23.8 Other current complications following acute myocardial infarction
0.666 0.334 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.666 0.334 0.000
Z35.5 Supervision of elderly primigravida
0.666 0.334 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.664 0.335 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.664 0.335 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.664 0.335 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.664 0.335 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.664 0.335 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.664 0.336 0.000
M06.34 Rheumatoid nodule (Hand)
0.663 0.336 0.000
E13.9 Without complications
0.663 0.337 0.000
Z65 Problems related to other psychosocial circumstances
0.663 0.337 0.000
Z64 Problems related to certain psychosocial circumstances
0.663 0.337 0.000
Z62 Other problems related to upbringing
0.663 0.337 0.000
Z61 Problems related to negative life events in childhood
0.663 0.337 0.000
Z59 Problems related to housing and economic circumstances
0.663 0.337 0.000
Z58 Problems related to physical environment
0.663 0.337 0.000
Z56 Problems related to employment and unemployment
0.663 0.337 0.000
Z55 Problems related to education and literacy
0.663 0.337 0.000
I33 Acute and subacute endocarditis
0.662 0.338 0.000
I95 Hypotension
0.662 0.338 0.000
I52 Other heart disorders in diseases classified elsewhere
0.662 0.338 0.000
I48 Atrial fibrillation and flutter
0.662 0.338 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.662 0.338 0.000
I41 Myocarditis in diseases classified elsewhere
0.662 0.338 0.000
I40 Acute myocarditis
0.662 0.338 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.662 0.338 0.000
I32 Pericarditis in diseases classified elsewhere
0.662 0.338 0.000
I51.0 Cardiac septal defect, acquired
0.661 0.339 0.000
Q24 Other congenital malformations of heart
0.661 0.339 0.000
E16 Other disorders of pancreatic internal secretion
0.659 0.341 0.000
I46.9 Cardiac arrest, unspecified
0.659 0.341 0.000
M11 Other crystal arthropathies
0.658 0.342 0.000
O71.8 Other specified obstetric trauma
0.658 0.342 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.657 0.343 0.000
I49.8 Other specified cardiac arrhythmias
0.656 0.344 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.656 0.344 0.000
O71.4 Obstetric high vaginal laceration alone
0.655 0.345 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.655 0.345 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.654 0.346 0.000
Q21 Congenital malformations of cardiac septa
0.652 0.347 0.000
L29 Pruritus
0.652 0.348 0.000
Z60.9 Problem related to social environment, unspecified
0.649 0.350 0.000
Z60.8 Other problems related to social environment
0.649 0.350 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.649 0.350 0.000
Z60.4 Social exclusion and rejection
0.649 0.350 0.000
Z60.3 Acculturation difficulty
0.649 0.350 0.000
Z60.1 Atypical parenting situation
0.649 0.350 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.649 0.350 0.000
M41.9 Scoliosis, unspecified
0.649 0.351 0.000
I51.6 Cardiovascular disease, unspecified
0.649 0.351 0.000
I51.5 Myocardial degeneration
0.649 0.351 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.649 0.351 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.649 0.351 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.649 0.351 0.000
Z35.9 Supervision of high-risk pregnancy, unspecified
0.649 0.351 0.000
Z35.8 Supervision of other high-risk pregnancies
0.649 0.351 0.000
Z35.7 Supervision of high-risk pregnancy due to social problems
0.649 0.351 0.000
Z35.6 Supervision of very young primigravida
0.649 0.351 0.000
Z35.4 Supervision of pregnancy with grand multiparity
0.649 0.351 0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care
0.649 0.351 0.000
E66 Obesity
0.649 0.351 0.000
O73 Retained placenta and membranes, without haemorrhage
0.648 0.352 0.000
Z31 Procreative management
0.648 0.352 0.000
M96.8 Other postprocedural musculoskeletal disorders
0.647 0.353 0.000
L50-L54 Urticaria and erythema
0.647 0.353 0.000
Q66 Congenital deformities of feet
0.644 0.356 0.000
E40-E46 Malnutrition
0.643 0.357 0.000
I46.0 Cardiac arrest with successful resuscitation
0.643 0.357 0.000
Q76 Congenital malformations of spine and bony thorax
0.643 0.357 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.643 0.357 0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.642 0.358 0.000
Chapter VIII Diseases of the ear and mastoid process
0.642 0.358 0.000
D73.8 Other diseases of spleen
0.641 0.359 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.640 0.360 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.640 0.360 0.000
I49.5 Sick sinus syndrome
0.639 0.360 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.639 0.361 0.000
I35 Nonrheumatic aortic valve disorders
0.639 0.361 0.000
M72.9 Fibroblastic disorder, unspecified
0.639 0.361 0.000
M72.8 Other fibroblastic disorders
0.639 0.361 0.000
M72.6 Necrotizing fasciitis
0.639 0.361 0.000
M72.5 Fasciitis, not elsewhere classified
0.639 0.361 0.000
M72.4 Pseudosarcomatous fibromatosis
0.639 0.361 0.000
M72.3 Nodular fasciitis
0.639 0.361 0.000
M72.1 Knuckle pads
0.639 0.361 0.000
M76.6 Achilles tendinitis
0.637 0.362 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.637 0.363 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.637 0.363 0.000
O34.6 Maternal care for abnormality of vagina
0.637 0.363 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.637 0.363 0.000
O34.4 Maternal care for other abnormalities of cervix
0.637 0.363 0.000
O34.3 Maternal care for cervical incompetence
0.637 0.363 0.000
O34.0 Maternal care for congenital malformation of uterus
0.637 0.363 0.000
Q54 Hypospadias
0.635 0.365 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.634 0.365 0.000
I49.3 Ventricular premature depolarisation
0.634 0.366 0.000
M75.2 Bicipital tendinitis
0.633 0.367 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.633 0.367 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.633 0.367 0.000
E07.9 Disorder of thyroid, unspecified
0.632 0.368 0.000
O62.0 Primary inadequate contractions
0.631 0.369 0.000
O21 Excessive vomiting in pregnancy
0.631 0.369 0.000
I31.9 Disease of pericardium, unspecified
0.631 0.369 0.000
O86.4 Pyrexia of unknown origin following delivery
0.629 0.371 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.629 0.371 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.629 0.371 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.629 0.371 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.628 0.371 0.000
O66 Other obstructed labour
0.628 0.372 0.000
Q89 Other congenital malformations, not elsewhere classified
0.628 0.372 0.000
S10-S19 Injuries to the neck
0.627 0.373 0.000
M42 Spinal osteochondrosis
0.627 0.373 0.000
M40 Kyphosis and lordosis
0.627 0.373 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.627 0.373 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.627 0.373 0.000
Q28 Other congenital malformations of circulatory system
0.626 0.374 0.000
M89 Other disorders of bone
0.625 0.374 0.000
T78 Adverse effects, not elsewhere classified
0.626 0.374 0.000
M13 Other arthritis
0.625 0.375 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.625 0.375 0.000
Q00-Q07 Congenital malformations of the nervous system
0.625 0.375 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.623 0.377 0.000
Y52 Agents primarily affecting the cardiovascular system
0.623 0.377 0.000
S90-S99 Injuries to the ankle and foot
0.623 0.377 0.000
Q82 Other congenital malformations of skin
0.622 0.378 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.619 0.381 0.000
T92 Sequelae of injuries of upper limb
0.618 0.382 0.000
M05.8 Other seropositive rheumatoid arthritis
0.618 0.382 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.618 0.382 0.000
M05.2 Rheumatoid vasculitis
0.618 0.382 0.000
M05.1 Rheumatoid lung disease
0.618 0.382 0.000
M05.0 Felty's syndrome
0.618 0.382 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.617 0.383 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.617 0.383 0.000
O26.5 Maternal hypotension syndrome
0.617 0.383 0.000
O26.4 Herpes gestationis
0.617 0.383 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.617 0.383 0.000
O26.2 Pregnancy care of habitual aborter
0.617 0.383 0.000
O26.1 Low weight gain in pregnancy
0.617 0.383 0.000
O26.0 Excessive weight gain in pregnancy
0.617 0.383 0.000
L85 Other epidermal thickening
0.616 0.384 0.000
M20-M25 Other joint disorders
0.615 0.385 0.000
O00-O08 Pregnancy with abortive outcome
0.613 0.387 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.612 0.388 0.000
I36 Nonrheumatic tricuspid valve disorders
0.611 0.389 0.000
Z28 Immunisation not carried out
0.611 0.389 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.611 0.389 0.000
Z26 Need for immunisation against other single infectious diseases
0.611 0.389 0.000
Z25 Need for immunisation against other single viral diseases
0.611 0.389 0.000
Z24 Need for immunisation against certain single viral diseases
0.611 0.389 0.000
Z23 Need for immunisation against single bacterial diseases
0.611 0.389 0.000
Z20 Contact with and exposure to communicable diseases
0.611 0.389 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.611 0.389 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.611 0.389 0.000
M45-M49 Spondylopathies
0.610 0.390 0.000
D68.0 Von Willebrand's disease
0.609 0.391 0.000
O41 Other disorders of amniotic fluid and membranes
0.609 0.391 0.000
L10-L14 Bullous disorders
0.608 0.392 0.000
O80-O84 Delivery
0.607 0.392 0.000
D68.8 Other specified coagulation defects
0.607 0.393 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.606 0.394 0.000
D74 Methaemoglobinaemia
0.606 0.394 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.606 0.394 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.606 0.394 0.000
M10 Gout
0.606 0.394 0.000
Z22 Carrier of infectious disease
0.606 0.394 0.000
I49.0 Ventricular fibrillation and flutter
0.606 0.394 0.000
M99 Biomechanical lesions, not elsewhere classified
0.605 0.395 0.000
O46.8 Other antepartum haemorrhage
0.605 0.395 0.000
O46.0 Antepartum haemorrhage with coagulation defect
0.605 0.395 0.000
Q27 Other congenital malformations of peripheral vascular system
0.604 0.396 0.000
Q26 Congenital malformations of great veins
0.604 0.396 0.000
Q25 Congenital malformations of great arteries
0.604 0.396 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.604 0.396 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.604 0.396 0.000
D72 Other disorders of white blood cells
0.603 0.397 0.000
D59 Acquired haemolytic anaemia
0.603 0.397 0.000
M60 Myositis
0.601 0.399 0.000
Q23.1 Congenital insufficiency of aortic valve
0.600 0.400 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.600 0.400 0.000
D66 Hereditary factor VIII deficiency
0.600 0.400 0.000
E66.8 Other obesity
0.598 0.402 0.000
Z32.9 Pregnancy confirmed (erroneous code. See Z321)
0.598 0.402 0.000
Z32.1 Pregnancy confirmed
0.598 0.402 0.000
M62 Other disorders of muscle
0.597 0.403 0.000
I72.3 Aneurysm of iliac artery
0.596 0.404 0.000
M86 Osteomyelitis
0.596 0.404 0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec
0.596 0.404 0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other
0.596 0.404 0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot
0.596 0.404 0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg
0.596 0.404 0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh
0.596 0.404 0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm
0.596 0.404 0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm
0.596 0.404 0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region
0.596 0.404 0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites
0.596 0.404 0.000
L30.9 Dermatitis, unspecified
0.595 0.405 0.000
I72.9 Aneurysm of unspecified site
0.592 0.408 0.000
M72.2 Plantar fascial fibromatosis
0.592 0.408 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.592 0.408 0.000
I31.3 Pericardial effusion (noninflammatory)
0.591 0.409 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.590 0.410 0.000
O62.2 Other uterine inertia
0.590 0.410 0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified
0.590 0.410 0.000
O74.8 Other complications of anaesthesia during labour and delivery
0.590 0.410 0.000
O74.7 Failed or difficult intubation during labour and delivery
0.590 0.410 0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery
0.590 0.410 0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery
0.590 0.410 0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery
0.590 0.410 0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery
0.590 0.410 0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery
0.590 0.410 0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery
0.590 0.410 0.000
M94 Other disorders of cartilage
0.589 0.411 0.000
O71.9 Obstetric trauma, unspecified
0.589 0.411 0.000
O71.7 Obstetric haematoma of pelvis
0.589 0.411 0.000
O71.6 Obstetric damage to pelvic joints and ligaments
0.589 0.411 0.000
O71.5 Other obstetric injury to pelvic organs
0.589 0.411 0.000
O71.3 Obstetric laceration of cervix
0.589 0.411 0.000
O71.2 Postpartum inversion of uterus
0.589 0.411 0.000
O71.1 Rupture of uterus during labour
0.589 0.411 0.000
O71.0 Rupture of uterus before onset of labour
0.589 0.411 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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