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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs72732436
log Bayes Factor = 16.1169
Chromosome 1   position 99,464,107  (GRCh37) Explore rs72732436 on Ensembl!
Variant rs72732436 is part of Cluster X0095

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Chapter II Neoplasms
0.997 0.003 0.000
H04 Disorders of lachrymal system
0.995 0.005 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.994 0.006 0.000
C15-C26 Malignant neoplasms of digestive organs
0.994 0.006 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.990 0.010 0.000
K70 Alcoholic liver disease
0.988 0.012 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.988 0.012 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.988 0.012 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.986 0.014 0.000
W00-W19 Falls
0.984 0.016 0.000
K82 Other diseases of gallbladder
0.976 0.024 0.000
R50-R69 General symptoms and signs
0.976 0.024 0.000
H04.2 Epiphora
0.971 0.029 0.000
K76 Other diseases of liver
0.971 0.029 0.000
K83 Other diseases of biliary tract
0.971 0.029 0.000
W19 Unspecified fall
0.970 0.030 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.960 0.040 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.958 0.042 0.000
W19.9 Unspecified place
0.957 0.043 0.000
Chapter V Mental and behavioural disorders
0.956 0.044 0.000
M20-M25 Other joint disorders
0.947 0.053 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.946 0.054 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.946 0.054 0.000
R52 Pain, not elsewhere classified
0.942 0.058 0.000
C79 Secondary malignant neoplasm of other sites
0.940 0.060 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.940 0.060 0.000
H30-H36 Disorders of choroid and retina
0.939 0.061 0.000
H04.1 Other disorders of lachrymal gland
0.937 0.063 0.000
K82.8 Other specified diseases of gallbladder
0.937 0.063 0.000
R60 Oedema, not elsewhere classified
0.935 0.065 0.000
D80-D89 Certain disorders involving the immune mechanism
0.935 0.065 0.000
M05-M14 Inflammatory polyarthropathies
0.934 0.066 0.000
M50-M54 Other dorsopathies
0.929 0.071 0.000
K70.9 Alcoholic liver disease, unspecified
0.929 0.071 0.000
R94 Abnormal results of function studies
0.928 0.072 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.928 0.072 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.926 0.074 0.000
K83.0 Cholangitis
0.926 0.074 0.000
S90-S99 Injuries to the ankle and foot
0.923 0.077 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.921 0.079 0.000
H02 Other disorders of eyelid
0.921 0.079 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.919 0.081 0.000
S32 Fracture of lumbar spine and pelvis
0.918 0.082 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.918 0.082 0.000
R94.5 Abnormal results of liver function studies
0.916 0.084 0.000
K76.6 Portal hypertension
0.915 0.085 0.000
K74 Fibrosis and cirrhosis of liver
0.915 0.085 0.000
R60.0 Localised oedema
0.915 0.085 0.000
C25 Malignant neoplasm of pancreas
0.913 0.087 0.000
K70.3 Alcoholic cirrhosis of liver
0.908 0.092 0.000
M54 Dorsalgia
0.906 0.094 0.000
D60-D64 Aplastic and other anaemias
0.901 0.099 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.898 0.102 0.000
M25 Other joint disorders, not elsewhere classified
0.896 0.104 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.895 0.105 0.000
K02 Dental caries
0.894 0.106 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.894 0.106 0.000
S40-S49 Injuries to the shoulder and upper arm
0.892 0.108 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.890 0.110 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.890 0.110 0.000
K82.4 Cholesterolosis of gallbladder
0.889 0.111 0.000
S32.0 Fracture of lumbar vertebra
0.889 0.111 0.000
F10.2 Dependence syndrome
0.888 0.112 0.000
M80-M85 Disorders of bone density and structure
0.886 0.114 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.884 0.116 0.000
C60-C63 Malignant neoplasms of male genital organs
0.884 0.116 0.000
K90-K93 Other diseases of the digestive system
0.882 0.118 0.000
R63 Symptoms and signs concerning food and fluid intake
0.882 0.118 0.000
S00-S09 Injuries to the head
0.882 0.118 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.879 0.121 0.000
K83.1 Obstruction of bile duct
0.878 0.122 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.877 0.123 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.873 0.127 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.872 0.128 0.000
M54.5 Low back pain
0.869 0.131 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.868 0.132 0.000
C71 Malignant neoplasm of brain
0.867 0.133 0.000
R54 Senility
0.865 0.135 0.000
K76.9 Liver disease, unspecified
0.865 0.135 0.000
K12 Stomatitis and related lesions
0.864 0.136 0.000
R52.1 Chronic intractable pain
0.864 0.136 0.000
T87 Complications peculiar to reattachment and amputation
0.861 0.139 0.000
M65-M68 Disorders of synovium and tendon
0.860 0.140 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.859 0.141 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.858 0.142 0.000
C18 Malignant neoplasm of colon
0.854 0.146 0.000
Chapter XXI Factors influencing health status and contact with health services
0.852 0.148 0.000
T88.4 Failed or difficult intubation
0.851 0.149 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.844 0.156 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.841 0.159 0.000
R29.6 Tendency to fall, not elsewhere classified
0.841 0.159 0.000
R25 Abnormal involuntary movements
0.840 0.160 0.000
K74.3 Primary biliary cirrhosis
0.839 0.161 0.000
R52.2 Other chronic pain
0.839 0.161 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.834 0.166 0.000
R59 Enlarged lymph nodes
0.829 0.171 0.000
K02.9 Dental caries, unspecified
0.829 0.171 0.000
Chapter I Certain infectious and parasitic diseases
0.828 0.172 0.000
H02.4 Ptosis of eyelid
0.827 0.173 0.000
M86-M90 Other osteopathies
0.823 0.177 0.000
K72 Hepatic failure, not elsewhere classified
0.822 0.178 0.000
K08 Other disorders of teeth and supporting structures
0.821 0.179 0.000
W19.2 School, other institution and public administrative area
0.820 0.180 0.000
K01 Embedded and impacted teeth
0.820 0.180 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.819 0.181 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.819 0.181 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.818 0.182 0.000
M10 Gout
0.817 0.183 0.000
Chapter VI Diseases of the nervous system
0.815 0.185 0.000
M24 Other specific joint derangements
0.815 0.185 0.000
F10.3 Withdrawal state
0.814 0.186 0.000
H04.4 Chronic inflammation of lachrymal passages
0.814 0.186 0.000
S20-S29 Injuries to the thorax
0.812 0.188 0.000
M54.56 Low back pain (Lumbar region)
0.811 0.189 0.000
D64 Other anaemias
0.811 0.189 0.000
M35 Other systemic involvement of connective tissue
0.809 0.191 0.000
K70.1 Alcoholic hepatitis
0.808 0.192 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.805 0.195 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.805 0.195 0.000
C16 Malignant neoplasm of stomach
0.805 0.195 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.804 0.196 0.000
Chapter XXII Codes for special purposes
0.802 0.197 0.000
C25.9 Pancreas, unspecified
0.802 0.198 0.000
M25.5 Pain in joint
0.802 0.198 0.000
C64-C68 Malignant neoplasms of urinary tract
0.801 0.199 0.000
M00-M03 Infectious arthropathies
0.800 0.200 0.000
H21 Other disorders of iris and ciliary body
0.800 0.200 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.799 0.201 0.000
H33 Retinal detachments and breaks
0.799 0.201 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.798 0.202 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.798 0.202 0.000
S00 Superficial injury of head
0.796 0.204 0.000
K14 Diseases of tongue
0.795 0.205 0.000
H18 Other disorders of cornea
0.794 0.206 0.000
H35 Other retinal disorders
0.794 0.206 0.000
H04.9 Disorder of lachrymal system, unspecified
0.793 0.207 0.000
W19.1 Residential institution
0.792 0.208 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.787 0.213 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.785 0.215 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.785 0.215 0.000
H55-H59 Other disorders of eye and adnexa
0.784 0.216 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.783 0.216 0.000
D50-D53 Nutritional anaemias
0.783 0.217 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.783 0.217 0.000
M81 Osteoporosis without pathological fracture
0.781 0.219 0.000
S70-S79 Injuries to the hip and thigh
0.781 0.219 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.779 0.221 0.000
R56 Convulsions, not elsewhere classified
0.778 0.222 0.000
H02.3 Blepharochalasis
0.777 0.223 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.776 0.224 0.000
K92 Other diseases of digestive system
0.776 0.224 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.775 0.225 0.000
S91 Open wound of ankle and foot
0.775 0.225 0.000
H34 Retinal vascular occlusions
0.774 0.226 0.000
M54.59 Low back pain (Site unspecified)
0.774 0.226 0.000
Y86 Sequelae of other accidents
0.773 0.227 0.000
K86 Other diseases of pancreas
0.773 0.227 0.000
W50-W64 Exposure to animate mechanical forces
0.772 0.228 0.000
T87.6 Other and unspecified complications of amputation stump
0.770 0.230 0.000
K05 Gingivitis and periodontal diseases
0.769 0.231 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.768 0.231 0.000
K76.8 Other specified diseases of liver
0.768 0.232 0.000
X10-X19 Contact with heat and hot substances
0.766 0.233 0.000
R58 Haemorrhage, not elsewhere classified
0.766 0.234 0.000
C22.1 Intrahepatic bile duct carcinoma
0.766 0.234 0.000
S42 Fracture of shoulder and upper arm
0.765 0.234 0.000
C71.3 Parietal lobe
0.765 0.235 0.000
W08 Fall involving other furniture
0.764 0.236 0.000
M11 Other crystal arthropathies
0.764 0.236 0.000
C17 Malignant neoplasm of small intestine
0.763 0.237 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.763 0.237 0.000
R63.0 Anorexia
0.761 0.239 0.000
T85.2 Mechanical complication of intraocular lens
0.760 0.240 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.760 0.240 0.000
C15 Malignant neoplasm of oesophagus
0.760 0.240 0.000
H16 Keratitis
0.758 0.241 0.000
H02.1 Ectropion of eyelid
0.757 0.243 0.000
Q80-Q89 Other congenital malformations
0.757 0.243 0.000
M13 Other arthritis
0.757 0.243 0.000
K08.3 Retained dental root
0.756 0.244 0.000
R52.9 Pain, unspecified
0.753 0.247 0.000
M67 Other disorders of synovium and tendon
0.753 0.247 0.000
W06 Fall involving bed
0.752 0.248 0.000
K04 Diseases of pulp and periapical tissues
0.752 0.248 0.000
S80-S89 Injuries to the knee and lower leg
0.751 0.249 0.000
K70.0 Alcoholic fatty liver
0.751 0.249 0.000
F10.1 Harmful use
0.751 0.249 0.000
C18.0 Caecum
0.751 0.249 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.750 0.250 0.000
M54.6 Pain in thoracic spine
0.749 0.251 0.000
H43-H45 Disorders of vitreous body and globe
0.748 0.252 0.000
T79-T79 Certain early complications of trauma
0.748 0.252 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.748 0.252 0.000
C71.9 Brain, unspecified
0.747 0.253 0.000
D64.9 Anaemia, unspecified
0.747 0.253 0.000
K10 Other diseases of jaws
0.746 0.254 0.000
M60-M63 Disorders of muscles
0.745 0.255 0.000
K70.4 Alcoholic hepatic failure
0.745 0.255 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.745 0.255 0.000
Z60 Problems related to social environment
0.744 0.256 0.000
S32.1 Fracture of sacrum
0.743 0.257 0.000
C78.7 Secondary malignant neoplasm of liver
0.740 0.260 0.000
Y52 Agents primarily affecting the cardiovascular system
0.740 0.260 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.740 0.260 0.000
X20-X29 Contact with venomous animals and plants
0.739 0.261 0.000
R25.3 Fasciculation
0.739 0.261 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.738 0.262 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.737 0.263 0.000
K12.3 Oral mucositis (ulcerative)
0.736 0.264 0.000
K82.9 Disease of gallbladder, unspecified
0.736 0.264 0.000
C62 Malignant neoplasm of testis
0.735 0.265 0.000
M10.9 Gout, unspecified
0.733 0.267 0.000
S90 Superficial injury of ankle and foot
0.732 0.267 0.000
M54.4 Lumbago with sciatica
0.732 0.268 0.000
C25.0 Head of pancreas
0.729 0.271 0.000
F10.9 Unspecified mental and behavioural disorder
0.729 0.271 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.728 0.272 0.000
D62 Acute posthaemorrhagic anaemia
0.728 0.272 0.000
S10-S19 Injuries to the neck
0.728 0.272 0.000
H01 Other inflammation of eyelid
0.727 0.273 0.000
F60-F69 Disorders of adult personality and behaviour
0.727 0.273 0.000
C25.2 Tail of pancreas
0.726 0.274 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.726 0.274 0.000
S01 Open wound of head
0.726 0.274 0.000
C20 Malignant neoplasm of rectum
0.725 0.275 0.000
K74.6 Other and unspecified cirrhosis of liver
0.724 0.275 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.724 0.276 0.000
T66-T78 Other and unspecified effects of external causes
0.724 0.276 0.000
M07 Psoriatic and enteropathic arthropathies
0.724 0.276 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.722 0.278 0.000
M21 Other acquired deformities of limbs
0.721 0.278 0.000
C22.9 Liver, unspecified
0.721 0.279 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.720 0.280 0.000
Q23 Congenital malformations of aortic and mitral valves
0.720 0.280 0.000
V80-V89 Other land transport accidents
0.720 0.280 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.720 0.280 0.000
K07 Dentofacial anomalies [including malocclusion]
0.719 0.281 0.000
H02.0 Entropion and trichiasis of eyelid
0.718 0.282 0.000
C16.0 Cardia
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
K73 Chronic hepatitis, not elsewhere classified
0.717 0.283 0.000
K71 Toxic liver disease
0.717 0.283 0.000
Z46 Fitting and adjustment of other devices
0.717 0.283 0.000
K85 Acute pancreatitis
0.715 0.284 0.000
H05 Disorders of orbit
0.715 0.285 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
Z60.2 Living alone
0.714 0.286 0.000
M54.1 Radiculopathy
0.714 0.286 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.714 0.286 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.713 0.286 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.713 0.287 0.000
H04.8 Other disorders of lachrymal system
0.713 0.287 0.000
H04.6 Other changes in lachrymal passages
0.713 0.287 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.713 0.287 0.000
H04.0 Dacryoadenitis
0.713 0.287 0.000
M25.59 Pain in joint (Site unspecified)
0.713 0.287 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.712 0.288 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.712 0.288 0.000
C21 Malignant neoplasm of anus and anal canal
0.712 0.288 0.000
C23 Malignant neoplasm of gallbladder
0.712 0.288 0.000
M25.9 Joint disorder, unspecified
0.712 0.288 0.000
D55-D59 Haemolytic anaemias
0.712 0.288 0.000
R59.1 Generalised enlarged lymph nodes
0.712 0.288 0.000
S50-S59 Injuries to the elbow and forearm
0.711 0.289 0.000
Y84.8 Other medical procedures
0.710 0.290 0.000
H33.0 Retinal detachment with retinal break
0.710 0.290 0.000
G30-G32 Other degenerative diseases of the nervous system
0.709 0.291 0.000
M35.0 Sicca syndrome [Sjogren]
0.709 0.291 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.708 0.291 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.709 0.291 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.708 0.292 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.708 0.292 0.000
T86 Failure and rejection of transplanted organs and tissues
0.708 0.292 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.707 0.292 0.000
K03 Other diseases of hard tissues of teeth
0.707 0.293 0.000
K00 Disorders of tooth development and eruption
0.707 0.293 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.706 0.293 0.000
S42.0 Fracture of clavicle
0.706 0.293 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.706 0.294 0.000
C18.7 Sigmoid colon
0.706 0.294 0.000
K11 Diseases of salivary glands
0.706 0.294 0.000
D61 Other aplastic anaemias
0.706 0.294 0.000
R81 Glycosuria
0.706 0.294 0.000
W18 Other fall on same level
0.705 0.295 0.000
W17 Other fall from one level to another
0.705 0.295 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.705 0.295 0.000
W15 Fall from cliff
0.705 0.295 0.000
W14 Fall from tree
0.705 0.295 0.000
W12 Fall on and from scaffolding
0.705 0.295 0.000
W11 Fall on and from ladder
0.705 0.295 0.000
W10 Fall on and from stairs and steps
0.705 0.295 0.000
W09 Fall involving playground equipment
0.705 0.295 0.000
W05 Fall involving wheelchair
0.705 0.295 0.000
W04 Fall while being carried or supported by other persons
0.705 0.295 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.705 0.295 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.705 0.295 0.000
W00 Fall on same level involving ice and snow
0.705 0.295 0.000
M81.9 Osteoporosis, unspecified
0.705 0.295 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.704 0.296 0.000
D86 Sarcoidosis
0.703 0.296 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.703 0.297 0.000
Z43 Attention to artificial openings
0.703 0.297 0.000
R63.5 Abnormal weight gain
0.703 0.297 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.702 0.297 0.000
R82 Other abnormal findings in urine
0.702 0.298 0.000
R68 Other general symptoms and signs
0.701 0.299 0.000
K01.1 Impacted teeth
0.701 0.299 0.000
C60 Malignant neoplasm of penis
0.700 0.300 0.000
K82.3 Fistula of gallbladder
0.700 0.300 0.000
K82.2 Perforation of gallbladder
0.700 0.300 0.000
K82.0 Obstruction of gallbladder
0.700 0.300 0.000
W07 Fall involving chair
0.700 0.300 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.700 0.300 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.700 0.300 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.699 0.300 0.000
R62 Lack of expected normal physiological development
0.699 0.300 0.000
R64 Cachexia
0.699 0.300 0.000
R25.1 Tremor, unspecified
0.698 0.302 0.000
S40 Superficial injury of shoulder and upper arm
0.698 0.302 0.000
M31 Other necrotising vasculopathies
0.697 0.303 0.000
M91-M94 Chondropathies
0.697 0.303 0.000
C61 Malignant neoplasm of prostate
0.697 0.303 0.000
X60-X84 Intentional self-harm
0.697 0.303 0.000
M24.0 Loose body in joint
0.697 0.303 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.696 0.303 0.000
K76.7 Hepatorenal syndrome
0.696 0.304 0.000
K76.5 Hepatic veno-occlusive disease
0.696 0.304 0.000
K76.4 Peliosis hepatis
0.696 0.304 0.000
K76.3 Infarction of liver
0.696 0.304 0.000
K76.2 Central haemorrhagic necrosis of liver
0.696 0.304 0.000
K76.1 Chronic passive congestion of liver
0.696 0.304 0.000
K83.9 Disease of biliary tract, unspecified
0.696 0.304 0.000
K83.5 Biliary cyst
0.696 0.304 0.000
K83.4 Spasm of sphincter of Oddi
0.696 0.304 0.000
K83.3 Fistula of bile duct
0.696 0.304 0.000
K83.2 Perforation of bile duct
0.696 0.304 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.696 0.304 0.000
W19.8 Other specified place
0.696 0.304 0.000
W19.5 Trade and service area
0.696 0.304 0.000
W19.0 Home
0.696 0.304 0.000
W19.7 Farm
0.696 0.304 0.000
W19.6 Industrial and construction area
0.696 0.304 0.000
W19.3 Sports and athletics area
0.696 0.304 0.000
R80 Isolated proteinuria
0.695 0.304 0.000
M40-M43 Deforming dorsopathies
0.693 0.307 0.000
H36 Retinal disorders in diseases classified elsewhere
0.693 0.307 0.000
C18.4 Transverse colon
0.692 0.307 0.000
M06 Other rheumatoid arthritis
0.692 0.307 0.000
F80-F89 Disorders of psychological development
0.692 0.307 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.692 0.308 0.000
S41 Open wound of shoulder and upper arm
0.691 0.309 0.000
G90-G99 Other disorders of the nervous system
0.691 0.309 0.000
R63.4 Abnormal weight loss
0.690 0.310 0.000
V20-V29 Motorcycle rider injured in transport accident
0.689 0.311 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.689 0.311 0.000
S92 Fracture of foot, except ankle
0.689 0.311 0.000
S00.1 Contusion of eyelid and periocular area
0.689 0.311 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.688 0.312 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.688 0.312 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.688 0.312 0.000
H18.5 Hereditary corneal dystrophies
0.688 0.312 0.000
S32.5 Fracture of pubis
0.688 0.312 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.687 0.313 0.000
W13 Fall from, out of or through building or structure
0.686 0.314 0.000
Z46.6 Fitting and adjustment of urinary device
0.686 0.314 0.000
M25.54 Pain in joint (Hand)
0.685 0.315 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.685 0.315 0.000
F70-F79 Mental retardation
0.685 0.315 0.000
Chapter XIV Diseases of the genitourinary system
0.683 0.317 0.000
K83.8 Other specified diseases of biliary tract
0.683 0.317 0.000
R55 Syncope and collapse
0.683 0.317 0.000
W20-W49 Exposure to inanimate mechanical forces
0.682 0.317 0.000
H21.0 Hyphaema
0.682 0.318 0.000
R59.0 Localised enlarged lymph nodes
0.681 0.319 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.681 0.319 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.680 0.320 0.000
Y84.2 Radiological procedure and radiotherapy
0.680 0.320 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.680 0.320 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.679 0.321 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.679 0.321 0.000
M34 Systemic sclerosis
0.679 0.321 0.000
M33 Dermatopolymyositis
0.679 0.321 0.000
M32 Systemic lupus erythematosus
0.679 0.321 0.000
M30 Polyarteritis nodosa and related conditions
0.679 0.321 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.678 0.321 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.678 0.321 0.000
S37 Injury of urinary and pelvic organs
0.678 0.321 0.000
S36 Injury of intra-abdominal organs
0.678 0.321 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.678 0.321 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.678 0.321 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.678 0.321 0.000
S31 Open wound of abdomen, lower back and pelvis
0.678 0.321 0.000
M25.8 Other specified joint disorders
0.678 0.322 0.000
D75 Other diseases of blood and blood-forming organs
0.678 0.322 0.000
E20-E35 Disorders of other endocrine glands
0.678 0.322 0.000
K92.9 Disease of digestive system, unspecified
0.677 0.323 0.000
K65-K67 Diseases of peritoneum
0.677 0.323 0.000
C45 Mesothelioma
0.677 0.323 0.000
C79.6 Secondary malignant neoplasm of ovary
0.674 0.326 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.674 0.326 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.674 0.326 0.000
Q50-Q56 Congenital malformations of genital organs
0.673 0.326 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.673 0.327 0.000
N10-N16 Renal tubulo-interstitial diseases
0.673 0.327 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.673 0.327 0.000
H31 Other disorders of choroid
0.673 0.327 0.000
H30 Chorioretinal inflammation
0.673 0.327 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.673 0.327 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.672 0.328 0.000
C71.1 Frontal lobe
0.672 0.328 0.000
M67.8 Other specified disorders of synovium and tendon
0.671 0.329 0.000
S93.0 Dislocation of ankle joint
0.671 0.329 0.000
R60.1 Generalised oedema
0.670 0.329 0.000
D84 Other immunodeficiencies
0.670 0.330 0.000
D83 Common variable immunodeficiency
0.670 0.330 0.000
D82 Immunodeficiency associated with other major defects
0.670 0.330 0.000
D81 Combined immunodeficiencies
0.670 0.330 0.000
D80 Immunodeficiency with predominantly antibody defects
0.670 0.330 0.000
R27 Other lack of coordination
0.670 0.330 0.000
M54.2 Cervicalgia
0.670 0.330 0.000
M14 Arthropathies in other diseases classified elsewhere
0.670 0.330 0.000
M12 Other specific arthropathies
0.670 0.330 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.670 0.330 0.000
M08 Juvenile arthritis
0.670 0.330 0.000
M25.56 Pain in joint (Lower leg)
0.670 0.330 0.000
K12.1 Other forms of stomatitis
0.669 0.331 0.000
M80 Osteoporosis with pathological fracture
0.669 0.331 0.000
M84 Disorders of continuity of bone
0.668 0.332 0.000
H40-H42 Glaucoma
0.667 0.333 0.000
Q00-Q07 Congenital malformations of the nervous system
0.666 0.334 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.666 0.334 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.665 0.334 0.000
R94.7 Abnormal results of other endocrine function studies
0.665 0.334 0.000
R94.6 Abnormal results of thyroid function studies
0.665 0.334 0.000
R94.2 Abnormal results of pulmonary function studies
0.665 0.334 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.665 0.334 0.000
R94.0 Abnormal results of function studies of central nervous system
0.665 0.334 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.665 0.335 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.665 0.335 0.000
H17 Corneal scars and opacities
0.665 0.335 0.000
H15 Disorders of sclera
0.665 0.335 0.000
S42.00 Fracture of clavicle (closed)
0.664 0.336 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.664 0.336 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.664 0.336 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.664 0.336 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.664 0.336 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.664 0.336 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.664 0.336 0.000
F11 Mental and behavioural disorders due to use of opioids
0.664 0.336 0.000
A30-A49 Other bacterial diseases
0.664 0.336 0.000
R94.4 Abnormal results of kidney function studies
0.663 0.337 0.000
M54.3 Sciatica
0.662 0.338 0.000
S99 Other and unspecified injuries of ankle and foot
0.662 0.338 0.000
S98 Traumatic amputation of ankle and foot
0.662 0.338 0.000
S97 Crushing injury of ankle and foot
0.662 0.338 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.662 0.338 0.000
S95 Injury of blood vessels at ankle and foot level
0.662 0.338 0.000
S94 Injury of nerves at ankle and foot level
0.662 0.338 0.000
A80-A89 Viral infections of the central nervous system
0.661 0.338 0.000
F01 Vascular dementia
0.661 0.339 0.000
R57 Shock, not elsewhere classified
0.661 0.339 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.661 0.339 0.000
C70 Malignant neoplasm of meninges
0.661 0.339 0.000
C69 Malignant neoplasm of eye and adnexa
0.661 0.339 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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